Abortifacient Health Dictionary

Ruta chalepensis

Rutaceae

San: Gucchapatra;

Hin: Pismaram, Sadab, Satari;

Ben: Ermul;

Mal: Aruta, Nagatali;

Tam: Aruvadam, Arvada;

Kan: Sadabu, Nagadali; soppu, Simesdanu;

Tel: Sadapa, Aruda

Importance: Common rue or Garden rue also known as Herb of Grace due to its service in the Roman Catholic Church for sprinkling the holy water among the congregation, is an aromatic perennial herb. The plant is useful in vitiated conditions of kapha and vata, strangury, fever, flatulence, colic, amenorrhoea, epilepsy and hysteria. The oil acts as a stimulant for uterine and nervous systems. The fresh leaves are used for rheumatalgia. The juice obtained from the leaves is given to children for helminthic infections and is good for odontalgia and otalgia (Warrier et al, 1996). The dried leaves, powdered and combined with aromatics, are given as a remedy for dyspepsia and with the fresh leaves a tincture is made which is used as an external remedy in the first stages of paralysis (Nadkarni, 1998).

Distribution: The plant is a native of South Europe and it is found in subtropical countries. It is commonly cultivated in Indian gardens.

Botany: Ruta chalepensis Linn.syn. R. graveolens Linn. var. angustifolia Sensu Hook. f. belongs to the family Rutaceae. It is an aromatic perennial herb growing upto 75cm height. Leaves are compound, shortly petiolate with ultimate segments oblong or obovate-oblong. Flowers are yellow. Fruits are capsules and shortly pedicelled (Warrier et al, 1996).

Agrotechnology: The plant is suited to areas which are about 1000m above mean sea level and with moderate rainfall and sunlight. The plant can be propagated either by seeds or stem cuttings. Seeds are to be sown in seedbeds. Stem cuttings of length 20-25cm are to be planted in polybags for rooting. About 3-4 months old seedlings can be transplanted to pots and harvested when plants attain 6-8 months age. In highlands land is to be ploughed to a fine tilth, mixed with organic manure and seedlings are to be transplanted at a spacing of 45cm between plants. Irrigation is essential during summer months. Regular weeding is to be done. The plant is not attacked by any serious pests and diseases. Harvesting commences from sixth month onwards. The economic part is the whole plant and the oil extracted from it (Prasad et al, 1997).

Properties and activity: Roots contain coumarins-xanthyletin and (-)-byakangelicin. The alkaloids are rutacridone-epoxide, gravacridonol and its monomethyl ether, gravacridonchlorine, furacridone, 1-hydroxy-3-methoxy-N-methylacridone, iso-gravacridonechlorine, dictamine, r-fragarine and skimmianine. Skimmianine is also present in leaves and stem. Leaves and stem also contain graveolinine (1-methyl-2(3’,4’-methylenedioxyphenol)-4-methoxy- quinoline). Aerial parts give coumarins bergapten, xanthotoxin and psoralen. Coumarin- imperatin has also been reported from the plant. Herb contains alkaloids such as kokusagenine, rutamine(methylgraveoline) and graveoline(1-methyl-2(3’,4’- methylenedioxyphenyl)-4-quinoline). Tissue culture of the plant gives furacridone alkaloids-1-hydroxyrutacridone-epoxide, rutagravin and gravacridonol. Gravacridondiol and its glucoside have been obtained from the root tissue culture. The essential oil from leaves, stem and root yielded aliphatic ketones including 2-nonanone (10-35%), undecyl-2-acetate (0.5-15%), 2-nonyl acetate (trace-10%), nonylacetate, nonanol, 2-nonylpropionate, 2- nonylpropionate, 2-undecanol and its esters. The oil from roots gave pregeijerene also.

The plant is spasmolytic which is due to the presence of bergapten, xanthotoxin, the essential oil and a coumarin. It is also antispasmodic, emmenagogue, irritant, abortifacient and anti-bacterial. Leaf is analgesic, antirheumatic, antihysteric and anthelmintic (Husain et al, 1992).... garden rue

Jacq.

Synonym: Ambroma augusta Linn. f.

Family: Sterculiaceae.

Habitat: Throughout the hotter and moister parts of India, from Punjab and Uttar Pradesh, eastwards to Arunachal Pradesh, Assam, Meghalaya and Tripura, ascending to 1,200 m, southwards in Peninsular India.

English: Perennial Indian Hemp, Devil's Cotton.

Ayurvedic: Pishaacha Kaarpaasa, Pivari.

Unani: Ulat-kambal.

Siddha/Tamil: Sivapputtuti.

Folk: Kumal, Sanukapaasi.

Action: Rootbark—emmena- gogue (used for dysmenorrhoea, amenorrhoea), abortifacient, galac- totrophic.

The root contains abromine (betaine), friedelin, abromasterol, abro- masterol A, choline, beta-sitosterol, stigmasterol and octacosanol. Leaves, reported to be useful in treating uterine disorders, contain taraxerol, its acetate and lupeol.

Dosage: Leaf juice—10-20 ml. Rootbarkpowder—3-6 g. (CCRAS.)... abroma augusta

Linn.

Family: Amaranthaceae.

Habitat: Throughout the tropical and subtropical regions, up to an altitude of 2,100 m, in the southern Andaman Islands.

English: Prickly Chaff Flower.

Ayurvedic: Apaamaarga, Chirchitaa, Shikhari, Shaikharika, Adahshalya, Mayura, Mayuraka, Kharamanjari, Kharapushpaa, Pratyakpushpaa, Aaghaat, Vashira, Kanihi.

Unani: Chirchitaa.

Siddha/Tamil: Naayuruvi.

Folk: Chirchitta, Chichidaa, Latjeeraa.

Action: Astringent, pectoral (ashes of the plant used in asthma and cough), diuretic, hepatoprotective, emmenagogue. Benzene extract of the plant exhibited abortifacient activity. The flowers, ground and mixed with sugar, are given for menorrhagia. Roots—astringent, haemostatic. Seeds—emetic; used for biliousness. Essential oil— antifungal.

Key application: As astringent, emetic. (Indian Herbal Pharmacopoeia.)

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of the whole plant in lipid disorders and obesity, the root for its blood-purifying property.

The plant juice and ash are used for treating bleeding piles. An alkaline powder of the plant is used in preparing Kshaarasutra of Ayurvedic medicine, which is recommended for treating fistula-in-ano.

The whole plant contains the alkaloids achyranthine and betaine. Achy- ranthine, a water-soluble alkaloid, is reported to dilate blood vessels, lower blood pressure, decrease heart rate and increase the rate and amplitude of respiration. It also shows spasmodic effects on the rectus muscle of frog, diuretic and purgative action in albino rats.

The presence of ecdysterone and oleanolic acid is also reported in the root.

The ashes of the plant yield large quantities of potash. The seeds yield saponins and oleanolic acid and its ester.

The presence of tannins and glyco- sides is also reported in the plant.

Dosage: Whole plant—20-30 g for decoction. Root—5-10 g. (API Vols. II, III.) Ash—500 mg to 2 g. (CCRAS.)... achyranthes aspera

Linn.

Synonym: A. emarginatum Bedd.

Family: Adiantaceae.

Habitat: North Kanara and the Nilgiri and Palni hills at higher elevations.

Ayurvedic: Hansapadi (related sp.).

Action: Rhizomes—decoction abortifacient. Astringent and emetic. Emollient in coughs and diseases of the chest; sudorific.... adiantum aethiopicum

Cucurbitaceae

The family Cucurbitaceae includes a large group of plants which are medicinally valuable. The important genera belonging to the family are Trichosanthes, Lagenaria, Luffa, Benincasa, Momordica, Cucumis, Citrullus, Cucurbita, Bryonopsis and Corallocarpus. The medicinally valuable species of these genera are discussed below.

1. Trichosanthes dioica Roxb.

Eng: Wild Snake-gourd; San: Meki,Pargavi, Parvara, Patola;

Hin: Palval, Parvar

Ben: Potol;

Mal: Kattupatavalam, Patolam;

Tam: Kombuppudalai;

Tel: Kommupotta

Wild snake-gourd is a slender-stemmed, extensively climbing, more or less scabrous and woolly herb found throughout the plains of N. India, extending to Assam and W. Bengal. Tendrils are 2-4 fid. Leaves are 7.5x5cm in size, ovate-oblong, cordate, acute, sinuate- dentate, not lobed, rigid, rough on both surface and with a petiole of 2cm. Flowers are unisexual. Male flowers are not racemed but woolly outside. Calyx tube is 4.5cm long, narrow, teeth linear and erect. Anthers are free. Fruit is 5.9cm long, oblong or nearly spherical, acute, smooth and orange-red when ripe. Seeds are half-ellipsoid, compressed and corrugated on the margin (Kirtikar and Basu, 1988). The unripe fruit of this is generally used as a culinary vegetable and is considered very wholesome and specially suited for the convalescent. The tender shoots are given in decoction with sugar to assist digestion. The seeds are useful for disorders of the stomach. The leaf juice is rubbed over the chest in liver congestion and over the whole body in intermittent fevers (Nadkarni, 1998). The fruit is used as a remedy for spermatorrhoea. The fresh juice of the unripe fruit is often used as a cooling and laxative adjunct to some alterative medicines. In bilious fever, a decoction of patola leaves and coriander in equal parts is given. The fruit in combination with other drugs is prescribed in snakebite and scorpion sting (Kirtikar and Basu, 1988).

Fruits contain free amino acids and 5-hydroxy tryptamine. Fatty acids from seeds comprise elaeostearic, linoelic, oleic and saturated acids. The aerial part is hypoglycaemic. Leaf and root is febrifuge. Root is hydragogue, cathartic and tonic. Unripe leaf and fruit is laxative (Husain et al, 1992). The plant is alterative and tonic. Leaves are anthelmintic. Flower is tonic and aphrodisiac. The ripe fruit is sour to sweet, tonic, aphrodisiac, expectorant and removes blood impurities.

The other important species belonging to the genus Trichosanthes are as follows.

T. palmata Roxb. T. cordata Roxb. T. nervifolia Linn.

T. cucumerina Linn.

T. anguina Linn.

T. wallichiana Wight. syn. T. multiloba Clarke

2. Lagenaria vulgaris Ser. syn. Cucurbita Lagenaria Linn. ; Roxb.

Eng: Bottle gourd San: Alabu Hin: Lauki, Jangli-khaddu

Ben: Lau, Kodu

Mal: Katuchuram, Churakka

Tam: Soriai-kay

Tel: Surakkaya

Bottle gourd is a large softly pubescent climbing or trailing herb which is said to be indigenous in India, the Molucas and in Abyssinia. It has stout 5-angled stems with bifid tendrils. Leaves are ovate or orbiculate, cordate, dentate, 5-angular or 5-lobed, hairy on both surfaces. Flowers are large, white, solitary, unisexual or bisexual, the males long and females short peduncled. Ovary is oblong, softly pubescent with short style and many ovules. Fruits are large, usually bottle or dumb-bell-shaped, indehiscent and polymorphous. Seeds are many, white, horizontal, compressed, with a marginal groove and smooth. There are sweet fruited and bitter-fruited varieties (Kirtikar and Basu, 1988). The fruit contains a thick white pulp which, in the cultivated variety (kodu) is sweet and edible, while in the smaller wild variety (tamri) it is bitter and a powerful purgative. The seeds yield clear limpid oil which is cooling and is applied to relieve headache. The pulp of the cultivated forms is employed as and adjunct to purgatives and considered cool, diuretic and antibilious, useful in cough, and as an antidote to certain poisons. Externally it is applied as a poultice. The leaves are purgative and recommended to be taken in the form of decoction for jaundice (Nadkarni, 1998). In the case of sweet-fruited variety, the stem is laxative and sweet. The fruit is sweet oleagenous, cardiotonic, general tonic, aphrodisiac, laxative and cooling. In the case of bitter-fruited variety, the leaves are diuretic, antibilious; useful in leucorrhoea, vaginal and uterine complaints and earache. The fruit is bitter, hot, pungent, emetic, cooling, cardiotonic, antibilious; cures asthma, vata, bronchitis, inflammations ulcers and pains.

3. Luffa acutangula (Linn.) Roxb.

Eng: Ridged gourd; San: Dharmargavah, Svadukosataki;

Hin: Tori, Katitori;

Ben: Ghosha

Mal: Peechil, Peechinga;

Tam: Pikangai, Prikkangai;

Tel: Birakaya;

Kan: Kadupadagila

Ridged gourd or ribbed gourd is a large monoecious climber cultivated throughout India. It is with 5-angled glabrous stems and trifid tendrils. Leaves are orbicular-cordate, palmately 5-7 lobed, scabrous on both sides with prominent veins and veinlets. Flowers are yellow, males arranged in 12-20 flowered axillary racemes. Female flowers are solitary, arranged in the axils of the males. Ovary is strongly ribbed. Fruits are oblong-clavate with 10-sharp angles 15-30cm long, tapering towards the base. Seeds are black, ovoid-oblong, much compressed and not winged (Warrier et al, 1995). The leaves are used in haemorrhoids, leprosy, granular-conjunctivitis and ringworm. The seeds are useful in dermatopathy. The juice of the fresh leaves is dropped into the eyes of children in granular conjunctivitis, also to prevent the lids from adhering at night on account of excessive meihomian secretion (Nadkarni, 1998). Fruits are demulcent, diuretic, tonic, expectorant, laxative and nutritive. The seeds are bitter, emetic, cathartic, expectorant and purgative.

The other important species of the genus Luffa are:

L. aegyptiaca Mill.

L. acutangula var. amara Clarke

L. echinata Roxb.

4. Benincasa hispida (Thumb.) Cogn. syn. B. cerifera Savi.

Eng: Ash gourd, White gourd melon; San: Kusmandah;

Hin: Petha, Raksa;

Ben: Kumra

Mal: Kumpalam;

Tam: Pusanikkai;

Kan: Bile Kumbala;

Tel: Bodigummadi

Ash gourd or White gourd melon is a large trailing gourd climbing by means of tendrils which is widely cultivated in tropical Asia. Leaves are large and hispid beneath. Flowers are yellow, unisexual with male peduncle 7.5-10cm long and female peduncle shorter. Fruits are broadly cylindric, 30-45cm long, hairy throughout and ultimately covered with a waxy bloom. The fruits are useful in asthma, cough, diabetes, haemoptysis, hemorrhages from internal organs, epilepsy, fever and vitiated conditions of pitta. The seeds are useful in dry cough, fever, urethrorrhea, syphilis, hyperdipsia and vitiated conditions of pitta (Warrier et al,1993). It is a rejuvenative drug capable of improving intellect and physical strength. In Ayurveda, the fresh juice of the fruit is administered as a specific in haemoptysis and other haemorrhages from internal organs. The fruit is useful in insanity, epilepsy and other nervous diseases, burning sensation, diabetes, piles and dyspepsia. It is a good antidote for many kinds of vegetable, mercurial and alcoholic poisoning. It is also administered in cough, asthma or respiratory diseases, heart diseases and catarrah. Seeds are useful in expelling tapeworms and curing difficult urination and bladder stones. The important formulations using the drug are Kusmandarasayana, Himasagarataila, Dhatryadighrita, Vastyamantakaghrita, Mahaukusmandakaghrita, etc. (Sivarajan et al, 1994).

Fruits contain lupeol, -sitosterol, n-triacontanol, vitamin B, mannitol and amino acids. The fruit is alterative, laxative, diuretic, tonic, aphrodisiac and antiperiodic. Seed and oil from seed is anthelmintic (Husain et al, 1992).

5. Momordica charantia Linn.

Eng: Bitter gourd, Carilla fruit San: Karavellam

Hin: Karela, Kareli

Mal: Kaypa, Paval

Tam: Pavakkai, Paval, Pakar

Tel: Kakara

Bitter gourd or Carilla fruit is a branched climbing annual which is cultivated throughout India. It is a monoecious plant with angled and grooved stems and hairy or villous young parts. Tendrils are simple, slender and elongate. Leaves are simple, orbicular, cordate and deeply divided into 5-7 lobes. Flowers are unisexual, yellow and arranged on 5-10cm long peduncles. Fruits are 5-15cm long with 3-valved capsules, pendulous, fusiform, ribbed and beaked bearing numerous triangular tubercles. Seeds are many or few with shining sculptured surface. The roots are useful in coloptosis and ophthalmopathy. The leaves are useful in vitiated conditions of pita, helminthiasis, constipation, intermittent fever, burning sensation of the sole and nyctalopia. The fruits are useful in skin diseases, leprosy, ulcers, wounds, burning sensation, constipation, anorexia, flatulence, colic, helminthiasis, rheumatalgia, gout, diabetes, asthma, cough, dysmenorrhoea, impurity of breast milk, fever and debility. Seeds are useful in the treatment of ulcers, pharyngodynia, and obstructions of the liver and spleen. The leaves and fruits are used for external application in lumbago, ulceration and bone fractures and internally in leprosy, haemorrhoids and jaundice (Warrier et al, 1995). The drug improves digestion, calms down sexual urge, quells diseases due to pitta and kapha and cures anaemia, anorexia, leprosy, ulcers, jaundice, flatulence and piles. Fruit is useful in gout, rheumatism and complaints of liver and spleen (Nadkarni, 1954; Aiyer and Kolammal, 1966; Mooss, 1976; Kurup et al, 1979). Kaccoradi taila is an important preparation using the drug (Sivarajan et al, 1994).

The seeds give triterpene glycosides, named momordicosides A, B, C, D and E, which are glycosides of cucurbit-5-en-triol, tetraol or pentaol. Leaves and vines give tetracyclic triterpenes-momordicines I, II and III (bitter principles). Immature fruits give several non-bitter and 2 bitter cucurbitacin glycosides. Four of the non-bitter glycosides, momordicosides F1, F2, G and I and the bitter momordicosides; K and L have also been characterized. Fruits, seeds and tissue culture give a polypeptide which contained 17 types of amino acids and showed hypoglycaemic activity. Fruits also give 5-hydroxy tryptamine and a neutral compound charantin (a steroidal glucoside), diosgenin, cholesterol, lanosterol and -sitosterol. Leaf is emetic, purgative and antibilious. Fruit is stomachic, tonic, carminative, febrifuge, antirheumatic and hypoglycaemic. Root is astringent. Fruit and leaf is anti-leprotic. Fruit, leaf and root are abortifacient and anti-diabetic. Leaf and seed is anthelmintic. Seed oil possesses antifeeding and insecticidal properties. Unsaponifiable matter from seed oil exhibited pronounced inhibitory activity against gram negative bacteria. Seed and fruit are hypoglycaemic, cytotoxic and anti-feedant (Husain et al, 1992).

Other important species belonging to the genus Momordica are as follows.

M. dioica Roxb.

M. cochinchinensis Spreng.

M. tuberosa Cogn.

M. balsamina Linn.

6. Cucumis melo Linn. syn. C. melo Linn. var. cultis Kurz., C. pubescens

Willd., C. callosus (Rottl.) Cogn.

Eng: Sweet melon San,

Hin: Kharbuja

Ben: Kharmul

Mal: Mulam

Tam: Chukkari-kai, Thumatti-kai, Mulampazham

Tel: Kharbuja-doshavSweet melon is a creeping annual extensively cultivated throughout India, found wild in India, Baluchistan and tropical Africa. The stem is creeping, angular and scabrous. Leaves are orbicular-reniform in outline, 5-angled or lobed, scabrous on both surfaces and often with soft hairs. Lobes of leaves are not very deep nor acute and with 5cm long petiole. Female peduncle is 5cm. Fruit is spherical, ovoid, elongate or contorted, glabrous or somewhat hairy, not spinous nor tuberculate.

Cucumis melo includes two varieties, namely,

C. melo var. momordica syn. C. momordica Roxb.

C. melo var. utilissimus Duthie & Fuller. syn. C. utilissimus Roxb.

The fruit is eaten raw and cooked. Its pulp forms a nutritive, demulcent, diuretic and cooling drink. It is beneficial as a lotion in chronic and acute eczema as well as tan and freckles and internally in cases of dyspepsia. Pulp mixed with cumin seeds and sugar candy is a cool diet in hot season. Seeds yield sweet edible oil which is nutritive and diuretic, useful in painful discharge and suppression of urine. The whole fruit is useful in chronic eczema (Kirtikar & Basu, 1988).

Seeds contain fatty acids-myristic, palmitic, oleic, linoleic; asparagine, glutamine, citrulline, lysine, histidine, arginine, phenylalanine, valine, tyrosine, leucine, iso-leucine, methionine, proline, threonine, tryptophan and crystine. Seed is tonic, lachrymatory, diuretic and urease inhibitor. Fruit pulp is eczemic. Fruit is tonic, laxative, galactagogue, diuretic and diaphoretic. The rind is vulnerary (Husain et al, 1992).

7. Cucumic sativus Linn.

Eng: Cucumber, Common cucumber; San: Trapusah;

Hin,

Ben: Khira;

Mal: Vellari

Tam: Vellarikkai, Pippinkai;

Kan: Mullusavte;

Tel: Dosekaya

Cucumber is a climbing annual which is cultivated throughout India, found wild in the Himalayas from Kumaon to Sikkim. It is a hispidly hairy trailing or climbing annual. Leaves are simple, alternate, deeply cordate, 3-5 lobed with both surfaces hairy and denticulate margins. Flowers are yellow, males clustered, bearing cohering anthers, connective crusted or elevated above the cells. Females are solitary and thickly covered with very bulbous based hairs. Fruits are cylindrical pepo of varying sizes and forms. Seeds are cream or white with hard and smooth testa. The fruits are useful in vitiated conditions of pitta, hyperdipsia, burning sensation, thermoplegia, fever, insomnia, cephalgia, bronchitis, jaundice, haemorrhages, strangury and general debility. The seeds are useful in burning sensation, pitta, constipation, intermittent fevers, strangury, renal calculus, urodynia and general debility (Warrier et al, 1994). The leaves boiled and mixed with cumin seeds, roasted, powdered and administered in throat affections. Powdered and mixed with sugar, they are powerful diuretic (Nadkarni, 1998). The fruits and seeds are sweet, refrigerant, haemostatic, diuretic and tonic. Other important species belonging to the genus are:

C. trigonus Roxb. syn. C. pseudo-colocynthis

C. prophetarum Linn.

8. Citrullus colocynthis (Linn.) Schrader. syn. Cucumis colocynthis Linn.

Eng: Colocynth, Bitter apple; San: Visala, Mahendravaruni;

Hin: Badi indrayan, Makkal

Ben: Makhal;

Mal: Kattuvellari (Valutu), Valiya pekkummatti;

Tel: Etti-puchcha

Tam: Paitummatti, Petummatti;

Colocynth or Bitter apple is found, cultivated and wild, throughout India in warmer areas. It is an extensively trailing annual herb with bifid tendrils angular branching stems and wooly tender shoots. Leaves are deeply divided, lobes narrow thick, glabrous or somewhat hairy. Flowers are unisexual, yellow, both males and females solitary and with pale-yellow corolla. Fruit is a globose or oblong fleshy indehiscent berry, 5-7.5cm in diameter and variegated with green and white. Seeds are pale brown. The fruits are useful in tumours, ascites, leucoderma, ulcers, asthma, bronchitis, urethrorrhea, jaundice, dyspepsia, constipations, elephantiasis, tubercular glands of the neck and splenomegaly (Warrier et al, 1994). It is useful in abnormal presentations of the foetus and in atrophy of the foetus. In addition to the above properties, the root has a beneficial action in inflammation of the breasts, pain in the joints; externally it is used in ophthalmia and in uterine pains. The fruit and root, with or without is rubbed into a paste with water and applied to boils and pimples. In rheumatism, equal parts of the root and long pepper are given in pill. A paste of the root is applied to the enlarged abdomen of children (Kirtikar and Basu, 1988). The fruit is useful in ascites, biliousness, jaundice, cerebral congestion, colic, constipation dropsy, fever, worms and sciatica. Root is given in cases of abdominal enlargement, cough, asthma, inflammation of the breast, ulcers, urinary diseases and rheumatism. Oil from seeds is used for poisonous bites, bowel complaints, epilepsy and also for blackening the hair (Nadkarni, 1954; Dey, 1980). The important formulations using the root and fruit are Abhayarista, Mahatiktakam kasaya, Manasamitravatakam, Cavikasava, Madhuyastyadi taila, etc. (Sivarajan et al, 1994). The powder is often used as an insecticide. The extract should never be given without some aromatic to correct its griping tendency (Nadkarni, 1998).

Fruit contains a glycoside- colocynthin, its aglycone- -elaterin, citrulluin, citrullene and citrullic acid. Unripe fruit contains p-hydroxy benzyl methyl ester. Roots contain - elaterin and hentriacontane (Husain et al, 1992). Colocynth is, in moderate doses, drastic, hydrogogue, cathartic and diuretic. In large doses, it is emetic and gastro-intestinal irritant and in small doses, it is expectorant and alterative. Colocynthin is a cathartic and intensely bitter principle. It has a purgative action. All parts of the plant are very bitter. The fruit has been described as cathartic (Nadkarni, 1982).

9. Citrullus vulgaris Schrad. syn. C. lanatus (Thunb.) Mats. & Nakai.

Eng: Water melon; San: Tarambuja;

Hin: Tarbuj;

Ben: Tarbuz

Mal: Thannimathan;

Tam: Pitcha, Dharbusini

Watermelon is an extensively climbing annual which is largely cultivated throughout India and in all warm countries. It has thick angular branching stems. Tendrils are bifid, stout and pubescent. Leaves are long, deeply divided or moderately lobed, glabrous or somewhat hairy and hardly scabrous. Petiole is a little shorter than the limb and villous. Calyx-lobes are narrowly lanceolate, equalling the tube. Corolla is yellow within, greenish outside and villous. Lobes are ovate-oblong, obtuse and prominently 5-nerved. Fruit is sub-globose or ellipsoid, smooth, greenish or clouded, often with a glaucous waxy coating. Flesh is juicy, red or yellowish white. Seeds are usually margined. C. vulgaris var. fistulosus Duthie & Fuller. syn. C. fistulosus has its fruit about the size of small turnip, the seeds of which are used medicinally. The fruit is tasteless when unripe and sweet when ripe. The unripe fruit is used to cure jaundice. Ripe fruit cures kapha and vata and causes biliousness. It is good for sore eyes, scabies and itching. The seeds are tonic to the brain and used as a cooling medicine. An emulsion of the seeds is made into a poultice with the pounded leaves and applied hot in cases of intestinal inflammations (Kirtikar and Basu, 1988). Fruit juice is good in quenching thirst and it is used as an antiseptic in typhus fever with cumin and sugar. It is used as a cooling drink in strangury and affections of urinary organs such as gonorrhoea; in hepatic congestion and intestinal catarrh. The bitter watermelon of Sind is known as “Kirbut” and is used as a purgative.

Seeds yield a fixed oil and proteids; citrullin. Seeds are cooling, demulcent, diuretic, vermifuge and nutritive. Pulp is cooling and diuretic. Fruit-juice is cooling and refreshing (Nadkarni, 1982).

10. Curcurbita pepo Linn. syn. Pepo vulgaris et P. verrucosus Moench

Meth.

Eng: Pompion, Pumpkin, Vegetable Marrow; San: Karkaru, Kurkaru, Kushmandi

Hin,

Ben: Kadimah, Konda, Kumra, Safedkkadu;

Mal: Mathan, Matha

Tel: Budadegummadi, Pottigummadi

Pompion or Pumpkin is a climbing herb which is considered to be a native of America and cultivated in many parts of India. The stem and leaves are with a harsh prickly armature. Foliage is stiff, more or less rigid and erect. Leaves are with a broad triangular pointed outline and often with deep lobes. Corolla is mostly with erect or spreading (not drooping) pointed lobes, the tube narrowing towards the base. Peduncle is strongly 5-angled and little or much expanding near the fruit. The fruit is cooling and astringent to the bowels, increases appetite, cures leprosy, ‘kapha and vata’, thirst, fatigue and purifies the blood. The leaves are used to remove biliousness. Fruit is good for teeth, throat and eyes and allays thirst. Seeds cure sore chests, haemoptysis, bronchitis and fever. It is good for the kidney and brain. The leaves are used as an external application for burns. The seeds are considered anthelmintic. The seeds are largely used for flavouring certain preparations of Indian hemp, and the root for a nefarious purpose, viz., to make the preparation more potent. The seeds are taeniacide, diuretic and demulcent. The fruit is cooling, laxative and astringent. The leaves are digestible, haematinic and analgesic.

The other important species belonging to the genus Cucurbita is C. maxima Duchena, the seeds of which are a popular remedy for tape-worm and oil as a nervine tonic (Kirtikar & Basu, 1988).

11. Corallocarpus epigaeus Benth. ex Hook. f. syn. Bryonia epigaea Wight.

San: Katunahi;

Hin: Akasgaddah;

Mal: Kadamba, Kollankova

Tam: Akashagarudan, Gollankovai;

Tel: Murudonda, Nagadonda

Corallocarpus is a prostrate or climbing herb distributed in Punjab, Sind, Gujarat, Deccan, Karnataka and Sri Lanka. It is monoecious with large root which is turnip-shaped and slender stem which is grooved, zigzag and glabrous. Tendrils are simple, slender and glabrous. Leaves are sub-orbicular in outline, light green above and pale beneath, deeply cordate at the base, angled or more or less deeply 3-5 lobed. Petiole is long and glabrous. Male flowers are small and arranged at the tip of a straight stiff glabrous peduncle. Calyx is slightly hairy, long and rounded at the base. Corolla is long and greenish yellow. Female flowers are usually solitary with short, stout and glabrous peduncles. Fruit is stalked, long, ellipsoid or ovoid. Seeds are pyriform, turgid, brown and with a whitish corded margin. It is prescribed in later stages of dysentery and old veneral complaints. For external use in chronic rheumatism, it is made into a liniment with cumin seed, onion and castor oil. It is used in case of snakebite where it is administered internally and applied to the bitten part. The root is given in syphilitic rheumatism and later stages of dysentery. The plant is bitter, sweet, alexipharmic and emetic. The root is said to possess alterative and laxative properties (Kirtikar and Basu, 1988). Root contains a bitter principle like Breyonin (Chopra et al, 1980).

Agrotechnology: Cucurbits can be successfully grown during January-March and September- December. For the rainfed crop, sowing can also be started after the receipt of the first few showers.

Pits of 60cm diameter and 30-45cm depth are to be taken at the desired spacing. Well rotten FYM or vegetable mixture is to be mixed with topsoil in the pit and seeds are to be sown at 4-5/pit. Unhealthy plants are to be removed after 2 weeks and retained 2-3 plants/pit. FYM is to be applied at 20-25t/ha as basal dose along with half dose of N (35kg/ha) and full dose of P (25kg) and K (25kg). The remaining dose of N (35kg) can be applied in 2 equal split doses at fortnightly intervals. During the initial stages of growth, irrigation is to be given at an interval of 3-4 days and at alternate days during flowering and fruiting periods. For trailing cucumber, pumpkin and melon, dried twigs are to be spread on the ground. Bitter gourd, bottle gourd, snake gourd and ash gourd are to be trailed on Pandals. Weeding and raking of the soil are to be conducted at the time of fertilizer application. Earthing up may be done during rainy season. The most dreaded pest of cucurbits is fruit flies which can be controlled by using fruit traps, covering the fruits with polythene, cloth or paper bags, removal and destruction of affected fruits and lastly spraying with Carbaryl or Malathion 0. 2% suspension containing sugar or jaggery at 10g/l at fortnightly intervals after fruit set initiation. During rainy season, downy mildew and mosaic diseases are severe in cucurbits. The former can be checked by spraying Mancozeb 0.2%. The spread of mosaic can be checked by controlling the vectors using Dimethoate or Phosphamidon 0.05% and destruction of affected plants and collateral hosts. Harvesting to be done at least 10 days after insecticide or fungicide application (KAU,1996).... cucurbits

Piper longum

Piperaceae: San: Pippali;

Hin, Ben, Pun: Piplamul; Kan, Mal:Thippali ;

Tam: Thippili; Mar: Pimpli;

Tel: Pipppaloo; Ass: Piplu.

Introduction: Long pepper is a slender aromatic climber whose spike is widely used in ayurvedic and unani systems of medicine particularly for diseases of respiratory tract. Pipalarishta, Pippalyasava, Panchakola, Pippalayadilauha, and Lavana bhaskar churan are common ayurvedic preparations made out of the dry spikes of female types. Ittrifal fauladi, Angaruya-i-kabir and Majun khadar are well known unani preparations of long pepper. Its roots also have several medicinal uses. The root is useful in bronchitis, stomach ache, diseases of spleen and tumours. Fruit is useful in vata and kapha, asthma, bronchitis, abdominal complaints, fever, leucoderma, urinary discharges, tumours, piles, insomnia and tuberculosis. Root and fruit are used in gout and lumbago. The infusion of root is prescribed after parturition to induce the expulsion of placenta. The root and fruit decoction are used in acute and chronic bronchitis and cough. It contains the alkaloid piperine which has diverse pharmacological activities, including nerve depressant and antagonistic effect on electro- shock and chemo -shock seizures as well as muscular incoordination.

Distribution: The plant is a native of Indo-Malaya region. It was very early introduced to Europe and was highly regarded as a flavour ingredient by the Romans. The Greek name “Peperi”, the Latin “Piper” and the English “Pepper” were derived from the Sanskrit name “Pippali”. It grows wild in the tropical rain forests of India, Nepal, Indonesia, Malaysia, Sri lanka, Rhio, Timor and the Philippines. In India, it is seen in Assam, West Bengal, Uttar Pradesh, Madhya Pradesh, Maharashtra, Kerala, Karnataka.and Tamil Nadu. It is also cultivated in Bengal, Chirapunchi area of Assam, Akola-Amravati region of Maharashtra, Anamalai hills of Tamil Nadu, Orissa, Uduppi and Mangalore regions of Karnataka. Bulk of Indian long pepper comes from its wild growth in Assam, Shillong and West Bengal, supplemented by imports from Sri Lanka and Indonesia (Viswanathan,1995)

Botany: Piper longum Linn. is a member of Piperaceae family. The plant is a glabrous perennial under-shrub with erect or sub-scandent nodose stem and slender branches, the latter are often creeping or trailing and rooting below or rarely scandent reaching a few metres height. Leaves are simple, alternate, stipulate, and petiolate or nearly sessile; lower ones broadly ovate, cordate; upper ones oblong, oval, all entire, smooth, thin with reticulate venation; veins raised beneath. It flowers nearly throughout the year. Inflorescence is spike with unisexual small achlamydeous densely packed flowers and form very close clusters of small greyish green or darker grey berries. Female spikes with short thick stalk varying from 1.5 to2.5 cm in length and 0.5 to 0.7 cm in thickness.

A number of geographical races are available in different agroclimatic regions of India; the most popular being Assam, West Bengal and Nepal races. Piper officinarum DC; syn. Chavica officinarum Miquel, Piper pepuloides and Piper chaba Hunter are the other related species of importance.

Agrotechnology: Long pepper is a tropical plant adapted to high rainfall areas with high humidity. An elevation of 100-1000 m is ideal. It needs partial shade to the tune of 20-30% for best growth. The natural habitat of the plant is on the borders of streams. It is successfully cultivated in well drained forest soils rich in organic matter. Laterite soils with high organic matter content and moisture holding capacity are also suitable for cultivation.

Long pepper is propagated by suckers or rooted vine cuttings.15-20 cm long 3-5 nodded rooted vine cuttings establishes very well in polybags. The best time for raising nursery is March-April. Normal irrigation is given on alternate days. The rooted cuttings will be ready for transplanting in 2 months time. With the onset of monsoon in June the field is ploughed well and brought to good tilth. 15-20 cm raised beds of convenient length and breadth are taken. On these beds, pits are dug at 60 x 60 cm spacing and well decomposed organic manure at 100 g/pit is applied and mixed with the soil. Rooted vine cuttings from polybags are transplanted to these pits. Gap filling can be done after one month of planting.The crop needs heavy manuring at the rate of 20 t FYM/ha every year. Application of heavy dose organic matter and mulching increase water retention in the soil and control weeds. Small doses of chemical fertilisers can also be used. The crop needs irrigation once a week. Sprinkler irrigation is ideal. With irrigation the crop continues to produce spikes and off-season produce will be available. However, it is reported that unirrigated crop after the onset of monsoon grows vigorously and shows much hardiness than the irrigated crop.

Crop losses can be heavy due to pests and diseases. Mealy bugs and root grubs, attack the plant particularly during summer. Infested plants show yellowing and stunted growth. Application of systemic insecticides like nuvacron or dimecron will control the pests. Adults and nymphs of Helopeltis theivora severely feeds on the foliage which can be controlled by 0.25% neem kernel suspension. Rotting of leaves and vines during monsoon season is caused by Colletotrichum glorosporiodes and necrotic lesions and blights on the leaves during summer is caused by Colletotrichum and Cercospora spp. These diseases can be controlled by spraying of 1% Bordeaux mixture repeatedly. A virus like disease characterised by yellowing and crinkling of leaves, stunted growth and production of spikes of smaller size and inferior quality was also recently reported.

The vines start flowering six months after planting and flowers are produced almost throughout the year. The spikes mature in 2 months time. The optimum stage of harvest is when the spikes are blackish green. The pungency is highest at this stage. Spikes are hand picked when they become mature and then dried. The yield of dry spike is 400 kg /ha during first year, increases to 1000kg during third year and thereafter it decreases. Therefore, after 3 years the whole plant is harvested. The stem is cut close to the ground and roots are dug up. Average yield is 500 kg dry roots/ha (Viswanathan,1995).

Piper longum can also be cultivated as an intercrop in plantations of coconut, subabul and eucalyptus.

Post harvest technology: The harvested spikes are dried in sun for 4-5 days until they are perfectly dry. The green to dry spike ratio is 10:1.5 by weight. The dried spikes have to be stored in moisture proof containers. Stem and roots are cleaned, cut into pieces of 2.5-5 cm length, dried in shade and marketed as piplamool. There are three grades of piplamool, based on the thickness. The commercial drug consists 0.5-2.5 cm long ,0.5-2.5 mm thick, cylindrical pieces dirty light brown in colour and peculiar odour with a pungent bitter taste, producing numbness to the tongue.

Properties and activity: The spike of long pepper contains 4-5% piperine, piplartin, piperolactam, N-isobutyl deca trans-2-trans-4-dienamide and piporadione alkaloides, besides 0.7 % essential oil. Roots gave the alkaloids piperine, piperlongumine (piplartine) and piperlonguminine; sesamine, methyl 3, 4, 5-trimethoxy cinnamate. Stem gave triacoutane 22, 23 - dihydrostigmasterol. Fruit essential oil contains piperidine, caryophyllene and sesquiterpene alcohol (Atal et al, 1975).

The root is plungent, hot, stomachic, laxative, anthelmintic and carminative. The fruit is sweetish, pungent, hot, stomachic, aphrodisiac, alterative, laxative, antidysenteric, emmenagogue, abortifacient, diuretic and tonic. The essential oil is antimicrobial and anthelmintic.

N-isobutyl-deca-trans-2-trans-4-dienamide is antitubercular.

Piperine is hypotensive, antipyretic, analeptic, and nerve stimulant (Warrier et al, 1995).... long pepper

Indian bean (Catalpa longissima).

Plant Part Used: Bark.

Dominican Medicinal Uses: Bark: infusion, orally, for common cold, flu symptoms, menstrual disorders, uterine fibroids, dysmenorrhea and as an abortifacient.

Safety: Low toxicity shown in animal studies.

Laboratory & Preclinical Data: In vitro: anti-inflammatory, antinociceptive(plant extracts and constituents); oxytocic, uterine relaxant (leaf decoction).

In vivo: antiulcer (plant extracts).

* See entry for Roble in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.... roble

Terminalia spp.

Combretaceae

The genus Terminalia includes a large group of medicinally valuable trees. They belong to the family Combretaceae.

The most important medicinal species of the genus Terminalia are the following.

1) T. arjuna (Roxb.ex DC) Wight & Arn.

San: Arjunah, Kakubhah;

Hin: Arjun, Kahu, Kahua;

Mal: Marutu, Nirmarutu, Venmarutu, Attumarutu, Pulamatti;

Tam: Attumarutu, Nirmarutu, Vellaimarutu, Marutu;

Kan: Maddi.

It is a large evergreen tree commonly found in Madhya Pradesh, Bihar and Peninsular and India. It has buttressed trunk and spreading crown with drooping branches. Bark is smooth, grey outside and flesh coloured inside, flaking off in large flat pieces. Leaves are simple, sub-opposite, oblong or elliptic, coriaceous, crenulate, pale dull green above, pale brown beneath, often unequal sided, nerves 10-15 pairs and reticulate. Flowers are white, arranged in panicles of spikes with linear bracteoles. Fruits are ovoid or oblong with 5-7 short, hard angles or wings, the lines on the wings oblique and curving upward (Warrier et al 1996).

The bark is useful in fractures, ulcers, urethrorrhoea, leucorrhoea, diabetes, vitiated conditions of pitta, anaemia, cardiopathy, fatigue, asthma, bronchitis, tumours, internal and external haemorrhages, cirrhosis of the lever and hypertension. It is used in fractures and the powdered bark is taken with milk. The bark powder is diuretic and has a general tonic effect in cases of cirrhosis of liver. The bark has been considered by the ayurvedic physicians as well as by modern practitioners as a cardiac tonic. It is given as a decoction with milk (NRF, 1998). In Ayurveda, “Arjunaghrita” and “Arjunarishta” are two important cardiotonic preparations of this drug.

Fruits contain flavanones - arjunone and 5,7,2’, 4’ - tetramethoxy flavone and a chalcone - cerasidin. Other constituents are -sitosterol, friedelin, methyloleanolate, gallic acid, ellagic acid and arjunic acid. Bark gave a triterpene arjungenin, triterpene glucosides I, II and III. Stem bark gave flavones - baicalein and arjunolone characterised as 6,4’ - dihydraxy - 7-methoxy flavone. Stem bark yields oxalic acid and tannins besides complex glycosides (Bhatra et al, 1980). Bark is alexertic, styptic, antidysenteric, astringent, antiasthmatic, febrifuge, expectorant, cardiotonic aphrodisiac and diuretic. Fruit is deobstruent. Stem-bark is CVS and CNS active, diuretic and abortifacient. Aerial part is CNS depressant and semen coagulant.

2) T. alata Heyne ex Roth. Syn. T. tomentosa (Roxb. Ex. Dc.) W & A.

San: Dharaphala, Saradru, Sajada;

Hin. Ain;

Ben: Asan, Paishal;

Mal: Tehmbara;

Tam: Karramarda, Karu Murutha, Marudam, Pudavam.

This tree is distributed in Himalaya from Kangra eastwords to Goalpara in Assam and southwards throughout the Peninsular India, upto 1200 m. The bark of the tree is widely used in ulcers, fractures, bronchitis and diarrhoea. Hydrolysis of the gum gives oligosaccharides, disaccharides and monosaccharides. Leaves and fruits give -sitosterol. Bark is diuretic, antihaemorrhagic, styptic, cardiotonic and semen coagulant.

3) T. bellirica (Craertn.) Roxb.

San: Aksha, Anilaghanaka, Baheduka, Harya, Kalinda;

Hin: Bulla, Sagona;

Ben: Bahera, Baheri;

Tam: Akkam, Kalanduri, Tani;

Tel: Bhutavasamu Tadi, Tandra, Vibhutakamu.

Belliric Myrobalan is distributed throughout India, upto 900 m. Its bark is used in anaemia and leucoderma. The fruit is used in bronchitis, strangury, sore throat, diseases of eye, nose, heart and bladder, hoarseness and piles. It forms an important constituent of the ayurvedic drug ‘triphala’. Furits contain -sitosterol, gallic and ellagic acids, ethyl gallate, galloyl glucose, chebulagic acid and a cardiac glucoside bellaricanin. Alcoholic extract of the fruit possesses bile-stimulating activity. Alcoholic extract, 30 mg/kg does not affect blood pressure and respiration, but a higher dose of 60 mg/kg produces a fall in blood pressure. Furit has anticancerous and flower has spermicidal activity. Bark is mild diuretic. Fruit is astringent, antidropsical, antileprotic, antiinflammatory, antidiarrhoeal, antibilious, stomachic, antiasthmatic, tonic, anticephalgic, bechic, anthelmintic and attenuant. Kernel is narcotic. Semi -ripe fruit is purgative. Gum is demulcent (Husain et al, 1992)

4) T. bialata steud.

White Chugalam or silver grey wood is a common tree of Andaman Islands. Its bark is used as a cardiac stimulant.

5) T. Catappa Linn.

San: Grahadruma;

Hin: Badam;

Ben: Bangla Badam:

Tam: Natuvdom, Vadhamkottai;

Tel: Vedam, Voda Movettilla; Mar: Jangli Badama, Nat Badam.

Indian Almond or Tropical Almond is a popular tree cultivated throughout the warmer parts of India including Andaman Islands and other adjacent island. Oil from the kernel is a substitute for almond oil. The leaf is used in scabies and colic. Husk and endocarp contain tannins and pentosans. Oil from kernel contains oleic, linoleic, palmitic and stearic acids. Heart wood and stem bark contains -sitosterol and its palmitate. Heartwood in addition contains terminolic acid and triterpenic methyl esters. The aerial part of the plant is diuretic. The bark is astringent, mild diuretic, cardiotonic and antidysenteric. Leaf is sudorific, antirheumatic, antileprotic and anticephalalgic.

6) T. Coriacea (Roxb.) syn. T. tomentosa (Roxb. ex. DC.) W. & A. var. coriacea (Roxb.) C. B. Clarke

Tam: Anaimikkuvam, Sadagam;

Kan: Banapu;

Tel: Tani.

Leathery Murdah is a tree commonly used as a cardiac stimulant. It is widely distributed in the drier and warmer parts of Andhra Pradesh and Tamil Nadu upto 1350 m and in Central India. Its bark is mainly used as a cardiac stimulant and in atonic diarrhoea and callous ulcer. It is also CVS active.

7) T. myriocarpa Heurck. & Muell. Arg.

Ben: Panisaj; Ass: Hollock, Jhalna.

Hollock is a tree of the Himalayas widely distributed from Nepal to Arunachal Pradesh and in Assam at 1000 m. The bark is cardiac stimulant and mild diuretic. Bark give -sitosterol, fructose and 4,4’,5,5’,6,6’ - hexadydroxy diphenic acid dilactone. Bark also contains tannis - ellagic, gallic, chebulinic and chebulagic acids.

8) T. Pallida Brandis.

Tam: Vellai Kadukkay;

Tel: Tella Karaka, Velama Karka.

The plant is distributed throughout south India, upto 600m. Its bark is a mild diuretic.

9) T. Paniculata Roth.

Mal: Marutu, Pe Marutu, Ven Marutu;

Tam: Pei Kadukai, Ven Maruthu, Ilai Kadukkay, Marudu, Pullatti;

Tel: Nimiri, Pulamaddi, Putamanu, Pulanallamanu;

Kan: Maruva, Matti.

Flowering Murdah is a tree which is widely used in opium poisoning. It is distributed in the Western and Eastern Ghats, upto 1200m. The bark is used in parotitis and flowers in opium poisioning. Heart wood give 3, 3’-0-di-methylellagic acid and 3,4,3’0-trimethyl flavellagic acid, -sitosterol, an uncharacterized triterpene carboxylic acid; a glycoside -3,3’ di-0 - methyl ellagic acid - 4 - monoglucoside and 0 - penta methyl flavellogic acid. The stem bark is anticancerous, diuretic, cardiotonic CVS active and shows antagonism of amphetamine hyperactivity. Flower is anticholerin (Husain et al, 1992)

10) Terminalia chebula Retz. Syn. Myrobalanus chebula (Retz.) Gaertner

Eng: Chebulic myrobalan;

San,

Ben: Haritaki;

Hindi:Harara, Harir,

Har; Mal:Kadukka; Ass:Hilikha; Kan:Alale;

Mar:Habra,

Hirada;

Ori:Harida;

Guj: Hirdo;

Pun:Helela;

Tam:Amagola;

Tel: Karaka

Chebulic myrobalan is a medium deciduous tree, the fruit of which is a common constituent of “Triphala” capable of imparting youthful vitality and receptivity of mind and sense. It is a major constituent in the ayurvedic preparations like Abhayarishta, Abhaya modak, Haritaki khand, Triphaladi churnam and Agastya rasayanam. In allopathy it is used in astringent ointments. In unani system, it is used as a blood purifier. The pulp of the fruit is given in piles, chronic diarrhoea, dysentery, costiveness, flatulence, asthma, urinary disorders, vomiting, hiccup, intestinal worms, ascites and enlarged spleen and liver. Powder of the fruit is used in chronic ulcers and wounds, carious teeth and bleeding ulceration of the gums. The bark is a good cardiac tonic. The fruit is valuable for its tannins and dyes. The wood is used for building purposes, agricultural implements, plywood and match box industries. It is also grown as a shade tree.

The plant is found throughout India chiefly in deciduous forests, on dry slopes upto 900m especially in Bengal, Tamil Nadu, West coast and Western Ghats. The plant is also reported in Sri Lanka, Nepal and Burma.

Terminalia chebula Retz. syn. Myrobalanus chebula (Retz.) Gaertner comes under family Combretaceae. It is a medium sized deciduous tree with a cylindrical bole, rounded crown, spreading branches with dark brown bark and brownish gray heartwood. Leaves are simple, alternate or subopposite, ovate or elliptic ovate with short petioles bearing 2 glands below the blades. Flowers pale yellow or white in 4-10cm long axillary spikes. Calyx tube hairy pale yellow and 5 lobed; no petals. Stamens consist of 10 filaments subulate, anthers small; ovary inferior, 1-celled with 2-3 pendulous ovule. Fruit is a drupe, ovoid glossy, glabrous, faintly angled and yellow to orange brown in colour. Seeds are hard and pale yellow.

Kernel oil of Chebulic myrobalan contains 6 fatty acids viz. Palmitic, stearic, oleic, linoleic, arachidic and behenic acid. The fruits contain chebulinic acid, tannic acid, gallic acid, chebulin and tannin. Leaves contain terpenes and saponins and -sitosterol is present in the bark (Beri, 1970; Khalique and Nizamuddin, 1972; Miglani and Chawla, 1974). Fruits are astringent, purgative, tonic, carminative, alternative and antispasmodic. Flowers and fruits are antiviral and hypoglycaemic. Wood is oxytocic and hypothermic (Husain et al, 1992).

Agrotechnology: Terminalia species are, in general, subtropical trees. Young plants prefer shade while the matured plants tolerate light frost and drought. It grows well in hilly areas. This is propagated by seeds. Natural multiplication happens rarely due to the poor seeds germination. Seeds soaked in water for 48 hours before sowing in seedbeds which should be covered with straw after sowing. It is watered immediately. Usually it takes 3-5 months to germinate. It can be transferred to polybags at two-leaf stage. One-year-old seedlings are ready for transplanting. For transplanting, pits are made of 50cm cube at a spacing of 4m. Organic manure, added regularly, promotes growth. Irrigation is required during first year. Weeds should be removed regularly. This plant grows slowly. It fruits within 6-7 years. This is continued for many years. It is coppiced well. Fruits are collected immediately after falling down or covered with soil to protect it from pests. Fruits dried well in sun and used or stored. The hard seed coat is removed before sowing.... terminalia

ERGOT of rye. Secale. Claviceps purpurea, Tulasne.

Constituents: indole alkaloids, tyramine, acetylcholine.

Action: abortifacient, parturient, haemostatic, hypertensive, uterine stimulant, oxytocic. Uses. Obstetrics.

Difficult childbirth. Applied to excite uterine contractions in the third stage of labour. Preparations. Liquid Extract. BPC 1954, dose, 0.6 to 1.2ml.

Registered medical practitioner only. ... ergot

suffix denoting causing or making. Example: abortifacient (causing abortion).... facient

Linn.

Family: Annonaceae.

Habitat: A native to South America and the West Indies; now cultivated throughout India.

English: Custard Apple, Sugar Apple, Sweet-sop.

Ayurvedic: Gandagaatra, Sitaa phala (also equated with Curcurbita maxima).

Unani: Sharifaa.

Siddha/Tamil: Sitaaphalam, Atta.

Action: Leaves—insecticide (seed powder, mixed with leaf juice is used for removing lice from scalp). Seeds—abortifacient. Root— purgative, used in blood dysentery.

Fruit—invigorating, sedative to heart, antibilious, antiemetic, expectorant. Dried, powdered unripe fruits—used for treating ulcers. Ripe fruit made into paste with betel leaves is applied to tumour to hasten suppuration. Leaves, bark, unripe fruit—strongly astringent; used for diarrhoea and dysentery.

A fraction of total alkaloid from roots exhibits antihypertensive, antispasmodic, antihistaminic and bron- chodilatory properties. Leaves contain a cardiotonic alkaloid, quinoline. Squamone and bullatacinone were selectively cytotoxic to human breast carcinoma.

In Cuban medicine, leaves are taken to reduce uric acid levels.... annona squamosa

Linn.

Synonym: Chamaemelum nobile (L.) Allioni.

Family: Asteraceae.

Habitat: The temperate regions of the Himalayas. Wild at several places.

English: Roman Chamomile, Double Chamomile.

Unani: Gul-e-Baabuuna.

Siddha/Tamil: Shimai chamantipu.

Action: Mild sedative, anticon- vulsant, antispasmodic, anti- inflammatory, mild analgesic; used externally for skin disorders, poultice of flowers in sprains and rheumatism.

Key application: Used mainly in France for mild spasmodic gastrointestinal disturbances and sluggishness of bowels, also for nervousness. (PDR.) (German Chamomile has been included by German Commission E among approved herbs, whereas Roman chamomile remains unapproved due to lack of clinical evidence.) The British Herbal Pharmacopoeia recognizes antispasmodic activity of Anthemis nobilis.

The flower heads contain volatile oil (including azulenes and bisabolol); sesquiterpene lactone (nobilin); flavo- noids, cyanogenic glycoside, bitter glu- coside (anthemic acid); acetylenic salicylic derivatives, coumarins (including scopolin), valerianic acid; tannins.

Azulenes and bisabolol are anti- inflammatory and antispasmodic, reducing histamine-induced reactions, including hay fever and asthma. Flavo- noids, especially anthemidin, are also antispasmodic. Valerianic acid and cyanogenic glycosides are sedative.

Flowers and root—abortifacient. Leaves—astringent. A decoction is used for gargling in stomatitis and aphthae.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of dried stembark in disorders of female genital tract and bleeding disorders.

The dried bark contains alkaloids, steroids, reducing sugars and also tannins (4.61%). The ether-soluble alkaloid of the bark shows antibacterial activity.

Dosage: Stembark—0.5-1.5 g powder. (API Vol. II.)... anthemis nobilis

Wormseed (Chenopodium ambrosioides). Plant Part Used: Leaf, aerial parts.Dominican Medicinal Uses: The leaf and aerial parts are traditionally prepared as an infusion or crushed to extract their juice which is administered orally for colic, diarrhea, stomach ache, intestinal parasites and gas.Safety: The leaves are widely consumed as a culinary seasoning in small amounts. Cases of contact dermatitis due to handling the plant have been reported. The leaves have shown relatively low toxicity in animal studies, and the seed oil and isolated constituents can be highly toxic.Contraindications: Avoid use of the oil in pregnancy (due to abortifacient effects) and young children (< 4 y). Internal use is contraindicated in the following conditions: gastro-intestinal inflammation (mucosal irritant), heart disease (cardiac depressive), liver disease (hepatotoxic) and kidney disease (renotoxic).Drug Interactions: Insufficient information identified in the available literature.Clinical Data: The leaf and plant extract have been investigated in human clinical trials for the following effects: antiparasitic and antiascariasis.Laboratory & Preclinical Data: The following biological activities of this plant have been demonstrated in laboratory and preclinical studies using in vitro or animal models: in vivo: analgesic, antimalarial, antimicrobial, antiulcerogenic, sedative (plant extracts or constituents); anthelmintic, antifungal (essential oil).In vitro: analgesic, antibacterial, antimalarial, insecticidal, sedative (plant extracts or constituents); antifungal (essential oil).* See entry for Apasote in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.... apasote

Celery (Apium graveolens variety dulce).

Plant Part Used: Stalk, leaves, roots, seeds.

Dominican Medicinal Uses: The stalks and leaves are traditionally eaten raw or taken as a juice for treating obesity, high blood pressure, high cholesterol, diabetes and menopausal hot flashes.

Safety: The stalks, leaf and root are widely consumed and generally considered safe. Cases of allergic reaction to the root have been reported. Plants infected with pink rot fungus can cause phototoxicoses.

Contraindications: Internal use of the seeds and essential oil are contraindicated during pregnancy (emmenagoge, abortifacient, uterine stimulating effects) and patients with renal disorders (potential kidney-irritating effect of oil).

Drug Interactions: Celery seeds and seed extract: anticoagulants, warfarin (risk of bleeding, drug potentiation); thyroxine (lowered T4 levels).

Laboratory & Preclinical Data: In vivo: anti-hyperlipidemic, anti-inflammatory, antinociceptive (plant extract); hepatoprotective (seeds).

In vitro: antimicrobial, antioxidant (plant extract); cercaricidal (essential oil); vasodilation (chemical constituent).

* See entry for Apio in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.... apio

Lam.

Synonym: A. bracteata Retz.

Family: Aristolochiaceae.

Habitat: Uttar Pradesh, Bengal, Madhya Pradesh and western peninsular India.

English: Bracteated Birthwort.

Ayurvedic: Kitamaari, Dhumrapa- traa, Naakuli.

Unani: Kiraamaar.

Siddha/Tamil: Aadutheendaappaalai, Kattusuragam.

Action: Oxytocic, abortifacient, emmenagogue.

Leaves and fruit contain ceryl alcohol, aristolochic acid and beta-sitos- terol. Aristolochic acid is insecticidal, poisonous, nephrotoxic. Leaf juice— vermifuge. Seeds—strong purgative. Products containing aristolochic acid are banned in the U.S., Canada, Great Britain, European countries and Japan.

The seed compounds, aristolochic acid and magnoflorine, induce contractions in the isolated uterus of pregnant rat and stimulate the isolated ileum of guinea pig. They also activate the muscarinic and serotoner- gic receptors in a variety of organs. Magnoflorine decreases arterial blood pressure in rabbits, and induces hypothermia in mice.

See also A. longa.... aristolochia bracteolata

Linn.

Family: Aristolochiaceae.

Habitat: Throughout the country, mainly in the plains and lower hilly regions.

English: The Indian Birthwort.

Ayurvedic: Ishvari, Gandhnaakuli, Naagadamani, Arkamuula.

Unani: Zaraavand-Hindi.

Siddha/Tamil: Adagam.

Folk: Isarmuula, Isrola.

Action: Oxytocic, abortifacient, emmenagogue.

Aristolochia sp. contain aristolochic acids and aristolactams.... aristolochia indica

Linn.

Family: Aristolochiaceae. English: European Birthwort. Unani: Zaraawand Taweel.

Action: Oxytocic, abortifacient, emmenagogue.

Aristolochic acid and its Me es- ter—strongly abortifacient, showed damage to liver and kidney. Roots— anti-oestrogenic. A cytotoxic lignan, savinin, has been isolated from the roots.

Aristolochic acid also has an effect against adenosarcoma and HeLa cells in culture; however, it is suspected to be carcinogenic.

Aristolochia extracts show a pronounced enhancement of phagocytosis by leucocytes, granulocytes and peritoneal macrophages, due to the presence of aristolochic acids.

Tardolyt-coated tablets, which contain 0.3 mg of aristolochic acid, increase phagocytosis in healthy men.

Aristolochic acid also exhibits reduction of some of the toxic effects of prednisolone, chloramphenicol and tetracycline in experiments in vitro, and a reduction in the rate of recurrent herpes lesions in vivo.... aristolochia longa

Linn.

Synonym: B. repens Linn. B. procumbens Roxb.

Family: Nyctaginaceae.

Habitat: Throughout India as a weed.

English: Horse-purslane, Hogweed.

Ayurvedic: Rakta-punarnavaa, Punarnavaa, Katthilla, Shophaghni, Shothaghni. Varshaabhu (also equated with Trianthema portu- lacastrum Linn., which exhibits anti-inflammatory, antipyretic and analgesic activity).

Unani: Itsit, Bishkhaparaa.

Siddha/Tamil: Mookkirattai.

Folk: Gadaha-purnaa.

Action: Diuretic, anti-inflammatory, antiarthritic, spasmolytic, antibacterial (used for inflammatory renal diseases, nephrotic syndrome, in cases of ascites resulting from early cirrhosis of liver and chronic peritonitis, dropsy associated with chronic Bright's diseases, for serum uric acid levels). Root—anticon- vulsant, analgesic, expectorant, CNS depressant, laxative, diuretic, abortifacient.

Key application: As diuretic, hepatoprotective. (Indian Herbal Pharmacopoeia.)

B. repanda, synonym B. chinensis Linn., roots exhibited antihepatotox- ic activity against carbon tetrachloride galactosamine-and paracetamol- induced intoxication in rats. Powdered root gave encouraging results in spermatorrhoea and leucorrhoea.

The chloroform and methanolic extracts of the roots and aerial parts of B. diffusa also exhibited antihepatotox- ic activity against carbon tetrachloride- induced intoxication in rats.

Punarnavaa is official in IP as a diuretic. The diuretic action of the drug is attributed to the presence of xanthone, beta-ecdysone. Flavonoid, arbinofura- noside, present in the drug, was found to lower serum uric acid in experimental animals, as also in humans.

Punarnavaa has been reported to increase serum protein level and reduce urinary protein extraction in clinical trials in patients suffering with nephrotic syndrome. The activity is attributed to the presence of rotenoids in various parts of the plant.

An antifibrinolytic agent, punar- navoside, has been found to stop IUCD-induced bleeding in monkeys. The drug contains quinolizidine alkaloids.

Dosage: Whole plant—20-30 g for decoction (API Vol. I); root—1-3 g powder; 10-20 ml fresh juice. (API Vol. III.)... boerhavia diffusa

Sw.

Family: Caesalpiniaceae.

Habitat: Cultivated in gardens throughout India.

English: Barbados Pride, Peacock Flower.

Ayurvedic: Padangam, Ratnagandhi, Krishnachuudaa.

Siddha/Tamil: Mayirkonrai, Nalal.

Folk: Guleturaa, Sankeshwara.

Action: Leaves—laxative, antipyretic. Used in Eastern India as a substitute for senna. Dried and powdered leaves are used in erysipelas. Flowers—anthelmintic. Also used for cough and catarrh. Root—a decoction is prescribed in intermittent fevers. Bark— emmenagogue, abortifacient.

The plant contains a flavonoid, my- ricitroside. The leaves, flowers and fruits contain tannins, gums, resin, benzoic acid. Presence of cyanidin- 3,5-diglucoside is also reported from the flowers, hydrocyanic acid from the leaves. The root contains caesalpin type diterpenoids along with sitosterol.

The leaves have displayed anticancer activity in laboratory animals. A diter- penoid, isolated from the root, also showed anticancer activity.

In Pakistan, the leaf and flower extract exhibited activity against Grampositive bacteria.... caesalpinia pulcherrima

Linn.

Family: Caricaceae.

Habitat: Native to West Indies and Central America; now cultivated in Uttar Pradesh, Punjab, Rajasthan, Gujarat, Maharashtra and South India.

English: Papaya, Papaw.

Ayurvedic: Erand-karkati, Papitaa.

Unani: Papitaa Desi.

Siddha/Tamil: Pappaali, Pappayi.

Action: Ripe fruit—stomachic, digestive, carminative, diuretic, galactagogue. Useful in bleeding piles, haemoptysis, dysentery and chronic diarrhoea. Seeds— emmengagogue, abortifacient, vermifuge. Juice of seeds is administered in enlarged liver and spleen, and in bleeding piles.

Key application: Papain, the enzyme mixture extracted from raw papain (latex of Carica papaya), has been included among unapproved herbs by German Commission E. Experiment-based as well as clinical research indicate that papain may be effective (in the treatment of inflammations) in high doses (daily dose 1500 mg corresponding to 2520 FIP units).

Unripe fruit—emmengagogue and abortifacient. Latex—applied topically on eczema, ringworm, psoriasis, corns, warts, sloughing wounds, carbuncles and eschar of burns.

Green parts of the plant and seed contain an alkaloid carpaine. Seeds also contain carpasemine.

Latex contain enzymes—papain and chymopapain and alkaloids carpaine and pseudocarpaine. A proteinaceous material from latex showed anticoagulant activity; in higher doses it is heart depressant and as a spasmogen on smooth muscle of guinea pig ileum. An alkaloid solution showed depressant action on heart, blood pressure and intestine.

The anthelmintic action of seeds against Ascaris lumbricoides is due to carpasemine.

Papain, an enzyme mixture prepared from the fruit, seeds and leaf, hydrolyses polypeptides, amides and esters, particularly when used in an alkaline environment, and is used in digestive disorders.

Papain inhibits platelet aggregation, which may further increase the risk of bleeding in patients also taking anticoagulants. Concurrent administration of cyclophosphamide with papain caused sever damage to lung tissues in rats. (Sharon M. Herr.)

Chymopapin C is an immunosup- pressive enzyme from plant extract. Carpaine, extracted from the plant, exhibited anti-tubercular activity, also antitumour in vitro, and hypotensive.

Dosage: Leaf—40-80 ml infusion; latex—3-6 g (CCRAS.)... carica papaya

(Linn.) Nutt.

Family: Ranunculaceae.

Habitat: Temperate Himalayas from Kashmir to Bhutan up to at 3,000-4,000 m.

English: Black Cohosh Root, Black Snake Root.

Folk: Cohosh, Jiuenti (Punjab).

Action: Sedative, anti-inflammatory, antitussive, diuretic, emmenagogue. Used in homoeopathy for rheumatic diseases of nervous, hysterical women, suffering from uterine affections; also for locomotor ataxia.

Key application: In climacteric (menopausal), neurovegetative ailments, premenstrual discomfort and dysmenorrhoea. (German Commission E, ESCOP.)

The rhizome contains triterpene gly- cosides (including actein, cimigoside, cimifugine and racemoside; isofla- ones (including formononetin; isofer- ulic acid; volatile oil, tannin.

Pharmacological studies have shown that the menthol extract binds to oestrogen receptors in vitro and in rat uteri; this activity is thought to be due to the presence of formononetin. Racemoside exhibited antiulcer activity in mice. Isoferulic acid lowered body temperature in rats.

The rhizome is hypotensive in animals; a central nervous system depressant and antispasmodic in mice; causes peripheral vasodilation in human. Also exhibits anti-inflammatory (The British Herbal Pharmacopoeia) and hy- poglycaemic activity.

Actein has been studied for use in treating peripheral arterial disease. (Expanded Commission E Monographs.)

Clinically, the rhizome and root constituents of Black Cohosh does not seem to affect hormonal levels, such as estradiol, LH, FSH and pro- lactin. (Natural Medicines Comprehensive Database, 2007.)

Cimicifuga foetida L. root is used in bronchial and rheumatic diseases. Aqueous EtOH extract is used in cosmetic preparations for protecting skin; also used for preventing oral diseases and bad breath.

White Cohosh, used for urinogen- ital disorders, is equated with Actea pachypoda, synonym A. alba, A. rubra. Blue Cohosh has been identified as Caulophyllum thalictroides. It is toxic and abortifacient.... cimicifuga racemosa

(Fr.) Tul.

Family: Hypocreaceae.

Habitat: A fungous parasite on a number of grasses particularly in rye, cultivated in the Nilgiris and at Chakrohi farm in Jammu.

English: Ergot of Rye. Fungus of Rye.

Ayurvedic: Annamaya, Sraavikaa.

Unani: Argot.

Siddha/Tamil: Ergot.

Action: Uterine stimulant. Oxy- tocic, abortifacient, parturient, vasoconstrictor, haemostatic. Used in obstetrics (difficult childbirth, for exciting uterine contractions in the final stages of parturition). Also used after abortion for removal of the placenta. It is no more employed in internal haemorrhages, as it has been found to raise blood pressure in pulmonary and cerebral haemorrhage. Included among unapproved herbs by German Commission E.

The fungus gave indole alkaloids. The ergometrine or ergonovine group includes ergometrine and ergometri- nine. The ergotamine group includes ergotamine and ergotaminine. The er- gotoxine group includes ergocristine, ergocristinine, ergocryptine, ergo- cryptinine, ergocornine and ergo- corninine. The fungus also contains histamine, tyramine and other amines, sterols and acetylcholine.

The alkaloids of ergot are being used independently (not as a herbal medicine). Ergotamine is used to relieve migrainous headaches as it is a vasoconstrictor and has antisero- tonin activity. Ergometrine is used after childbirth in the third stage of labour and for post-partum haemorrhage, as it is a powerful uterine stimulant, particularly of the puerperal uterus. (Both the constituents are used under medical supervision). Er- gocornine significantly inhibited the development of induced mammary tumours in rats. The derivatives of ergot alkaloids are known to have suppressing effect on human breast cancer in initial stages. This activity is linked to prolactin inhibitory action.

The extract is toxic at 1.0-3.9 g, ergot alkaloids at 1 g in adults, 12 mg in infants. (Francis Brinker).

Dosage: Whole plant—10-30 ml infusion. (CCRAS.)... claviceps purpurea

Linn.

Family: Iridaceae.

Habitat: Cultivated in Kashmir up to 2,000 m and in Chaubattia in Uttar Pradesh.

English: Saffron, Crocus.

Ayurvedic: Kumkuma, Rudhira, Vadrika, Kaashmira, Kaashmiraka, Vaalhika, Agnishikhaa, Ghrusrrn, Rakta, Kshataja. Keshara (usually Keshara indicates Naagakeshara, Mesuaferrea Linn.)

Unani: Zaafraan.

Siddha/Tamil: Kumgumappoo (dried stigma).

Action: Stigma and style—nervine tonic, sedative, antispasmodic expectorant (in dry cough, whooping cough, bronchitis), stomachic, diaphoretic, emmenagogue.

The Ayurvedic Pharmacopoeia of India indicated the use of the stigma and style in migraine, chronic sinusitis, and in urinary obstruction, inflammation of the urinary tract.

The saffron is used in Chinese medicine for melancholia, depression, shock and menstrual disorders.

Saffron contains a volatile oil composed of terpenes, terpene alcohols and esters. The herb also contains crocin, picrocrocin, crocetin, carotenoids and riboflavin and thiamine.

Preliminary evidence suggests that crocetin may improved atherosclerosis by increasing plasma oxygen diffusion and decreasing cholesterol and triglyceride levels. In addition, cro- cetin binds to albumin, potentially increasing oxygen diffusion and improving atherosclerosis. (Natural Medicines Comprehensive Database, 2007.)

The stigma showed remarkable inhibitory effect on blood coagulation due to the presence of platelet aggregation inhibitor containing adenosine. It accelerated in vitro fibrinolytic activity of urokinase and plasmin.

Small amounts of Saffron stimulate gastric secretion; larger amounts stimulate uterine smooth muscle and exhibit emmenagogue and abortifacient effects.

Saffron extract showed cytotoxic and antimutagenic activity and antitu- mour activity against ascites tumours in mice. Chemical analysis indicated that the naturally occurring crocin may be the active principle responsible for the observed anticancer activity.

A xanthone, carotenoid glycosidic conjugate, mangi-crocin, isolated from saffron, showed significant adapto- genic activity. A natural antioxidant, isolated from saffron stem callus, showed better antioxidant activity than vitamin E. Saffron bulbs are toxic, stigmas in overdoses narcotic.

The dose of stigma and styles at 1.55.0 g is toxic. (Recommended dose : 0.5-1.5 g per day).

Dosage: Dried style and stigma—20-50 mg (API Vol. IV.)... crocus sativus

Seem.

Family: Bignoniaceae.

Habitat: Moist forests of central and southern India.

Ayurvedic: Mesha-shringi (also equated with Gymnena sylvestre R. Br.), Vishaanikaa.

Siddha/Tamil: Kattu Varsana, Kaddalatti, Kaliyacca.

Action: Fruits—bitter, carminative, used in diabetes, urinary disorders, bronchitis and skin diseases. Leaves—applied externally to swollen glands. Abortifacient.

The leaves yield luteolin, chrysin and its 7-rutinoside and glucoside.

Fruits are also known as Rshabhaka in the South.... dolichandrone falcate

Linn.

Family: Liliaceae.

Habitat: Native to East Africa and Saudi Arabia.

English: Dragon's Blood.

Ayurvedic: Khoonkharaabaa, Heeraadokhi.

Unani: Dammul-Akhwain.

Family: Araceae.

Habitat: Maharashtra and Karnata- ka; cultivated in the South.

Siddha/Tamil: Kattu Karunayikki- langu.

Folk: Jangali Suuran.

Action: Root—antidiarrhoeal, anti-inflammatory (prescribed for haemorrhoids), antispasmodic (used in asthma), emmenagogue, abortifacient.... dracontium polyphyllum

Vatke.

Family: Umbelliferae; Apiaceae.

Habitat: Jammu and Kashmir and Himachal Pradesh from 2,000 to 4,000 m.

Ayurvedic: Hingupatri.

Action: Abortifacient, antiimplantation. Being investigated as a potential contraceptive. A related species, F. silphion, was used in ancient Rome as a contraceptive.

The oil extracted from the leaves possesses mycotoxic property against dermatophytes, Trichophyton sp.

The ethanolic extract of the aerial parts produced dilation and congestion and hypertrophy in liver in rats.

The roots contain sesquiterpenoids. A coumarin, ferujol, isolated from the rhizome, showed abortifacient and anti-implantation activity at a single dose of 0.6 mg/kg in rats by oral administration in a suspension of gum acacia. The essential oil shows antimy- cotic activity.

Action: Resin—less strong than asafoetida; used in the same way as asafoetida and galbanum. Used in Middle East for rheumatic affections and backache.... ferula jaeschkeana

Mill.

Family: Umbelliferae; Apiaceae.

Habitat: Native to the Mediterranean region; now cultivated mainly in Punjab, Assam, Maharashtra and Vadodara (Gujarat).

English: Fennel. (Poison hemlock has been misidentified as fennel.)

Ayurvedic: Mishreyaa, Mishi, Mad- hurikaa, Madhuraa, Shatapushpaa, Shataahvaa. (Shatpushpaa is equated with Saunf and Shataahvaa with Soyaa. Some authors treat these as vice-versa.)

Unani: Baadiyaan, Saunf.

Siddha/Tamil: Sombu.

Action: Carminative, stomachic, antispasmodic, emmenagogue, galactagogue, anti-inflammatory, diuretic. Relieves bloating, nausea, settles stomach and stimulates appetite. Also used in amenorrhoea and enuresis.

Key application: In dyspepsias such as mild, spastic, gastrointestinal afflictions, fullness, flatulence. Fennel syrup or honey can be used for the catarrh of the upper respiratory tract in children. Fennel oil preparations not recommended during pregnancy. (German Commission E, ESCOP, WHO.)

German Commission E reported that fennel seed promotes gastrointestinal motility and in higher concentrations acts as antispasmodic. In experiments anethole and fenchone have been shown to have a secre- tolytic action in respiratory tract. The British Herbal Pharmacopoeia and Indian Herbal Pharmacopoeia report its carminative and spasmolytic property.

Fennel seed contain about 8% volatile oil (about 50-60% anethole, among others 10-15% fenchone and methyl- chavicol), flavonoids, coumarins (including bergapten) and sterols.

The extract of seeds inhibits the growth of micro-organism, especially Streptococcus mutans, that are responsible for dental caries and periodontal diseases.

The essential oil from the seed is reported to be antibacterial, antifungal, antioxidant, emmenagogue, oxytocic and abortifacient.

The fatty acid, petroselenic acid, obtained from the oil, exhibited antimicrobial activity.

Anethole, a major constituent of fennel seed/oil has been found to be an active estrogenic agent with minimal hepatotoxicity and no teratogenic effect.

The oil also exhibits anticarcino- genic activity and can be used as a che- moprotective agent.

It possesses antioxidant activity close to BHT.

Anethole and limonene are used in pharmaceutical compositions for decreasing the side effects of chemotherapy and increasing the immune function.

Limonene showed the capacity to inhibit mammary tumours in rats.

The boiling water extract of leaves shows hypotensive effect in rats.

The methanolic extract of seed showed antispasmodic activity, while aqueous extract accelerated the spontaneous movement of rabbit stomach.

Dosage: Dried fruit—3-6 g powder. (API Vol. I.)... foeniculum vulgare

Linn.

Family: Malvaceae.

Habitat: Cultivated mainly in Maharashtra, Tamil Nadu, Andhra Pradesh and Karnataka.

English: Asiatic Cotton, Levant Cotton, Uppam Cotton.

Ayurvedic: Kaarpaasa, Kaarpaasi, Kaarpaasaka, Rakta-Kaarpaasa, Shona-Kaarpaasa, Samudraantaa, Tuula, Pichu, Bhaaradwaaji, Tundikeri.

Unani: Pambahdaanaa. (Seed.)

Siddha/Tamil: Paruttikkootam

Action: Root bark—diuretic, oxytocic. Bark—emmenagogue, haemostatic. Seed—demulcent, laxative, expectorant, abortifacient, galactagogue, nervine, anticepha- lalgic.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the seed oil for toning up the breast.

The seed contains 21.3-25.2% protein, free gossypol 0.82-1.96%.

Dosage: Seeds, devoid of lint—3- 6 g powder. (API Vol. I.)... gossypium herbaceum

(Linn.) Hary.

Habitat: Native to South America, particularly its north-western parts. Also cultivated in India.

English: Egyptian Cotton, Sea- Island Cotton.

Ayurvedic: Kaarpaasa.

Siddha/Tamil: Semparutthi.

Folk: Kapaasa.

Action: Root—emmenagogue, oxytocic, abortifacient, parturient, lactagogue. Seed and leaf— antidysenteric. Seed—galacto- gogue, pectoral, febrifuge. Seed oil—used externally for clearing spots and freckles from the skin. Leaf—hypotensive, an- tirheumatic. Flower—used in hypochondriasis and bronchial inflammations.

The seed contains 26.2-27.9% protein; 1.22-2.42 free gossypol.... gracilaria lichenoides

Gloriosa superba

Liliaceae

San: Langali, Visalya, Agnishika,Shakrapushpi, Garbhaghatini

Hin: Kalihari

Mal: Menthonni

Tam: Akkinichilam

Pan: Kariari

Guj: Dudhiya vachnag

Kan: Nangulika Mar: Nagakaria

Ben: Bishalanguli Ori: Dangogahana

Tel: Adavinabhi

Importance: Glory lily is a glabrous herbaceous climber which yields different types of troplone alkaloids of medicinal importance. The major alkaloids are colchicine , 3-demethyl colchicine and colchicoside. There is another alkaloid gloriosine which promises to be even more effective than colchicine in plant breeding for inducing polyploidy. The genus has importance in the ornamental horticulture due to its bright flowers and wiry climbing stem.

The roots and rhizomes are used in traditional system of medicine. Its abortifacient and antipyretic properties have been mentioned in ancient classics “Charaka”. The name Garbhaghatini is due to this abortifacient activity. They are useful in the treatment of inflammations, ulcers, scrofula, hemorrhoids, pruritus, dyspepsia, helminthiasis, flatulence, intermittent fevers and debility. The root is given internally as an effective antidote against cobra poison. A paste of the root is also used as an anodyne; applications in bites of poisonous insects, snake bites, scorpion sting, parasitic skin diseases and leprosy (Nadkarni,1954; Chaudhuri and Thakur; 1994).

Distribution: The plant is distributed throughout tropical India upto an altitude of 2500m and in Andaman islands. It is also cultivated in tropical and South Africa, Madagaskar, Indonesia and Malasia. It is reported to be cultivated in some parts of Europe. In India it was cultivated in RRL, Jammu in 1960s. Recently it was taken up by Indian Council of Agricultural Research(ICAR). Cultivation of the plant is mostly confined to the Southern states of India besides its collection from wild sources.

Botany: Gloriosa superba Linn. belongs to Liliaceae family. It is a glabrous climbing herb with tuberous root stock grows over hedges and small trees. Stem is 6m long which grows to a height of 1.2-1.5m before the stem branches. Leaves are simple, alternate or whorled, sessile, ovate-lanceolate, 17x4.5cm, tip elongating into a spirally coiled tendril, base cordate and margin entire. Flowers are large in terminal racemes; perianth segments 6, linear, flexuosus and deflexed, basal half bright yellow, upper half red; stamens 6; ovary glabrous, 3-celled. Fruits are capsules, linear-oblong, upto 6.8cm long, 3 equal lobes, one or two lobes shorter in malformed fruits; green dried to pale and then black colour, dehisced into three sections. Seeds are oval in shape, testa spongy, embryo cylindric, 30-150 seeds per capsule, pale orange attached to the sutures. Tubers are cylindric, large, simple, ‘V’ shaped with the two limps equal or unequal in lenth pointed towards end brownish externally and yellowish internally. (Narain, 1977)

Agrotechnology: This is a rainy season plant and sprouts well in warm, humid and tropical conditions. It should be grown in sun as the plants in shade become weedy and thin and move towards light. G. superba is a shallow rooted plant and grows well in a variety of soils either clay or sand through out India. It grows well in a light porous soil with good drainage. For vigorous growth, greater blooms and strong tuber, a mixture of soil, sand and compost manure is recommended. The propagation is mainly by tubers, by division of rhizomes. Seeds remain dormant for 6-9 months and due to hard seed coat, about 20-30 days are required for germination and seeds may take 3-4 years before it matures to flower. Treatment of seeds by gibberellin(1-3 ppm) resulted in higher yield of colchicine in the plant and higher production of tubers. In tissue culture, young sprouts are cultured on Murashige and Skoog’s medium (Msb) supplemented with kinetin (1-4 mg/l). Direct regeneration of the explants are obtained.

The seeds and rhizomes are sown usually in the last week of June to mid July. The rhizomes are planted by splitting carefully into two from their ‘V’ shaped joints (two buds being at the extreme end of each rhizome) in lines 20cm apart at a distance of 20cm (while seeds are sown in lines at a distance of 4-6cm apart). They are watered regularly when the plants are growing. After green shoots appear 2-3 showers are weekly. The irradiation of the plant at 42% natural sunlight intensity increased the production of tuber and colchicine. They usually takes 6-10 weeks to flower after sprouting and then set on fruits. The fruits ripen at the end of October and after that aerial shoot eventually dies, leaving the fleshy tubers underground. The tubers are dug out with great care. An individual plant produces 50g tubers on an average. The average yield is approximately 4000-5000kg of rhizomes and 1000 kg of seed per hectare. The content of colchicine is usually 0.358% and 1.013% in tubers and seeds, respectively.

Post harvest technology: Lixivation of the material is done with 70% ethyl alcohol. Concentrated under vacuum to one third of its volume and extracted with chloroform for colchicine and related substances-concentration of the aqueous phase to syrup which is extracted 6-8 times with a mixture of CHCl3 - alcohol (4:1) to yield colchicoside.

Properties and activity: The flowers, leaves and tubers contain colchicine, superbin, N-formyl deacetyl colchicine, demethyl colochicine and lumicolchicine. Tubers also contain gloriosine. Leaves in addition, contain chelidonic acid, 2-hydroxy 6-methoxy benzoic acid and -sitosterol glucoside. Colchicine, demethyl colchicine and colchicoside have been reported from seeds. Rhizome is oxytocic, anticancerous, antimalarial, stomachic, purgative, cholagogue, anthelmintic, alterative, febrifuge and antileprotic. Leaf is antiasthmatic and antiinflammatory. Root shows antigonorrhoeic and antibiotic activity. This plant has poisonous effect to enviroment and livestock. The toxic properties are due to presence of alkaloids chiefly colchicine (Clewer et al, 1915).... glory lily

Linn.

Family: Boraginaceae.

Habitat: Throughout India.

English: Scorpion Tail.

Ayurvedic: Hastishundi Shrihastini, Vrischikaali.

Siddha/Tamil: Thaelkodukku.

Action: Plant—diuretic, astringent, emollient, vulnerary. Used as a local application for ulcers, wounds, sores, gum boils and skin affections. Decoction of leaves is used in urticaria and fevers; that of root in coughs. Flowers—emmenagogue in small doses, abortifacient in large doses. Masticated seeds— stomachic.

Aerial parts of the plant contain alkaloids—indicine (principal base), echinatine, supinine, heleurine, he- liotrine, lasiocarpine and lasiocarpine- N-oxide. Aerial parts and root gave an anticancer principle—indicine-N- oxide.

The aqueous and alcohol extracts of the plant possess oxytocic activity. The roots contain significant amounts of estradiol, a sex hormone.

The inflorescences are used by trib- als for scorpion bite.... heliotropium indicum

Linn.

Family: Ranunculaceae.

Habitat: Native to sub-alpine woods in Southern and Eastern Europe. Grown in Indian gardens.

English: Black Hellebore, Christmas Rose.

Ayurvedic: Khuraasaani Kutaki.

Unani: Kharbaq Siyah, Kutaki.

Action: Digitalis-like action in cardiac disorders, drastic purgative, abortifacient, diuretic, local anaesthetic, narcotic.

The rhizome contains cardiac glycosides; helleborin, helleborein, hellebrin and others based on helleborigenin.

Helleborin has a burning, acrid taste and is narcotic. Helleborein has a sweetish taste and is a highly active cardiac poison. Helleborin and veratrin (steroidal saponins), helle- brin or helleborein (steroid glycoside) are main constituents of the root and leaves. The plant irritates mucous membranes.

A related species, Helleborus virdis Linn. (Bear's Foot, Green Hellebore) is known as Kaali Kutaki and Krishna- bhedi. The plant contains magno- florine and corytuberine. The roots and rhizomes gave hellebrin, desgluco- hellebrin, hellebrigenin, bufatetraeno- lide, beta-ecdysterone and 5beta-hy- droxyecdysterone.... helleborus niger

Linn. var. saxatillis Palias.

Synonym: J. communis auct. non L.

Family: Pinaceae; Cupressaceae.

Habitat: Native to Europe and North America. Distributed in Western Himalayas from Kumaon westwards at 1,700-4,200 m.

English: Common Juniper.

Ayurvedic: Hapushaa, Havushaa, Haauber, Matsyagandha.

Unani: Abahal, Haauber, Hubb-ul- arar, Aarar.

Action: Berries—diuretic, urinary antiseptic, carminative, digestive, sudorific, anti-inflammatory, emmenagogue. Used for acute and chronic cystitis, renal suppression (scanty micturition), catarrh of the bladder, albuminuria, amenorrhoea, leucorrhoea. Aerial parts—abortifacient.

Key application: In dyspepsia. (German Commission E.) Juniper berry may increase glucose levels in diabetics. (ESCOP.) As a diuretic.

(The British Herbal Pharmacopoeia.)

The Ayurvedic Pharmacopoeia of India recommends the dried fruit in malabsorption syndrome.

Animal studies have shown an increase in urine excretion as well as a direct effect on sooth muscle contraction. (German Commission E, ESCOP.)Con- traindicated in kidney disease. (Sharon M. Herr.)

(In Kerala, Hapushaa and Mundi are considered to be synonyms; Syphaer- anthus indicus,Asteraceae, is used as Hapushaa.)

The major constituents of the volatile oil are alpha-pinene, sabinene and alpha-terpinene. Methanolic extract of the plant gave several labdane diter- penoids and diterpenes. The leaves contain the biflavones, cupressufla- vone, amentoflavone, hinokiflavone, isocryptomerin and sciadopitysin. The berries also contain condensed tannins. Seeds gave haemagglutinin.

Juniperus recurva Buch-Ham ex D. Don, syn. J. excelsa auct. non-Bieb. (temperate Himalaya from Kashmir to Bhutan) is known as Weeping Blue Juniper. J. macropoda Boiss. (the Himalaya from Nepal onwards) is known as Himalayan Indian Juniper. Both the species are used like J. communis var. saxatillis.

The berries gave a diterpene ketone, sugrol, beta-sitosterol glucoside and 10-nonacosanol.

Plant extract can be used in toothpastes and mouth-rinses to reduce dental plaque and bleeding.

Dosage: Dried fruit—2-6 g powder. (API, Vol. III.)... juniperus communis

Plumbago spp.

Plumbaginaceae

The genus Plumbago belonging to the family Plumbaginaceae is a popular and medicinally very important group of medicinal plants. Three species, namely P. rosea, P. zeylanica and P. auriculata have been identified. Among these P. rosea and P. zeylanica are important ones.

Plumbago, in general is an esteemed remedy for leucoderma and other skin diseases. The synonyms of fire like agnih, vahnih, etc. are attributed to this drug to indicate the very burning action of the root, causing blisters on the skin (daranah). The drug is used only after adequate curing and purification. Root is the officinal part and it enters into the composition of preparations like Citrakasavam, Dasamularista, Gulgulutiktaka kasaya, Yogarajachurna, etc.

1. P. rosea Linn. syn. P. indica Linn.

Eng: Rosy-flowered Leadwort; San: Citrakah, Dhahanah;

Hin: Lalcitra, Raktacitra;

Ben: Lalchita;

Mal: Kotuveli, Chettikkoduveli, Chuvannakotuveli;

Tam: Chenkotuveli, Cittiramulam;

Kan: Kempacitramula;

Tel: Yerracitramulam

Rosy-flowered leadwort or Fire plant is a native of Coromandel Coast. It is found throughout India, in moist situations as well as cultivated. The roots are useful in dyspepsia, colic, inflammations, cough, bronchitis, helmenthiasis, haemorrhoids, elephantiasis, chronic and intermittent fever, leprosy, leucoderma, ringworm, scabies, hepatosplenomegaly, amenorrhoea, odontalgia, vitiated conditions of vata, kapha and anaemia. It is a pretty subscandent perennial shrub with semi -woody striate stems and flexible branches. Leaves are simple, alternate oblong, short cuneate at the base passing into a very short amplexicaul, exauriculate, and reddish petiole. Flowers are bright red, arranged in long terminal spikes. The calyx ribs are covered with stipitate, bifarious and subsessile gland. Corolla tube is slender and four times as long as the calyx. The stout roots are cylindrical, irregularly bent, light yellowish brown with smooth surface having short transverse shallow fissures at the regions of the bents. A light yellowish juice excudes from the cut surface. A healthy plant may produce 18-20 stout roots (Warrier et al, 1995).

The chemical constituents include plumbagin and sitosterol glucoside. Clinical trials have demonstrated that plumbagin oil from P. indica is useful in common wart (Satyavati et al, 1987). The roots are acrid, astringent, thermogenic, anthelmintic, constipating, expectorant, antiinflammmatory, abortifacient, alterant, anti-periodic, carminative, digestive, sudorific, narcotic, gastric, nervous stimulant and rejuvenating. Root is a powerful sialogogue and vesicant.

2. P. zeylanica Linn.

Eng:White flowered Leadwort; San:Chitraka;

Hin, Ben:Chitarak, Chitra; Mal:Vellakotuveli

Tam: Sittragam, Chittiramoolam;

Kan: Vahini; Mar: Chitraka;

Tel: Chitramulam

White flowered Leadwort or Chitarak is found wild in peninsular India and mostly in West Bengal. Root is used externally in leprosy and other skin diseases or obstinate character, aphthae, abscesses, influenza, piles and anasarca. Juice is used externally in scabies and ulcers. One of the important preparations of Chitrak is “Yograjguggal”, prescribed for arthritis, rheumatism, etc. The other well known preparations are “Chitrak Adivati” and “ Chitraka Haritaki”. In Unani system it is an ingredient of “Aqaruva-i- Kabir”, “Hab Ashkhar”, “Ma’jun Baladur”, “Ma’jun Raig Mahi”, etc. It is a branched undershrub. Roots are long and tuberous. Stem is striate. Leaves are simple, alternate, short petioled, ovate or ovate-oblong, acute with entire or wavy margin, 7x3.8cm and glabrous. Flowers are white, arranged in terminal spikes. Calyx is tubular, glandular-hairy. Corolla tube is slender; limb rotate and 5 lobbed. Stamens are 5 on a disc. Style is slender with 5 stigmatic branches. Fruit is membranous capsule enclosed within the persistent calyx.

The roots of P. zeylanica have been exhaustively studied and naphthaquinones have been isolated, namely, plumbagin, 3-chlroplumbagin, droserone (Sidhu et al, 1971; Padhye et al, 1973), 3,3’-biplumbagin(Chitranone), zeylanone and iso-zeylanone and a coumarin, elliptinone (Sankaram et al, 1976, 1979). It also contains 1,2(3)-tetrahydro-3,3’-biplumbagin and plumbazeylanone. The leaf is antirheumatic. Root is appetiser, sudorific, relieves pain, vasicant, diuretic, caustic, antidiarrhoeal and expellent of phlegmatic tumours. Root is uterine stimulant. Root and fruits have antiimplantation activity. Plumbagin induces antiimplantation, has abortifacient and antiovulatory activity and causes selective testicular lesions in dogs. It is also a mitotic inhibitor. In lower concentration it behaves like a spindle, poison but in higher concentration it exhibits radiomimetic, nucleotoxic and cyclotoxic effects. It also has antibacterial, antifungal and anticoagulant activities and shows antagonism to amphetamine hyperactivity in mice.

3. P. auriculata Lam. syn. P. capensis

Eng: Blue flowered Leadwort;

Mal: Neelakotuveli

The blue flowered Leadwort is often grown in gardens throughout India (Moos, 1976; Chunekar, 1982; Sharma, 1983). It is a native of Cape Province in South Africa. It is a constituent of many Ayurvedic drugs (KAU, 1991). The plant is a subshrub growing to a height of 1-1.5m. Leaves are elliptic to obovate, 3-4 x 1.5-2cm. Inflorescence is a raceme of length 3-4cm. Corolla is blue to violet. Stamens are 5 in number. Flowers and fruits may be upto 12 in number (Matthew, 1995).

Agrotechnology: The plant is grown in tropical to subtropical ecosystems. Warm humid tropical climate is most suited. They come up well in almost all types of deep and well drained soils. It is propagated vegetatively by stem cuttings. Three stem cuttings of size 15cm long are planted in polybags of size 14x10cm. IAA and IBA treatments will improve rooting of cuttings. The land is to be ploughed well. About 4 tonnes of FYM are to be applied, mixed thoroughly and seed bed of size 50cm breadth, 1.5cm height and convenient length are to be prepared. On these beds pits are taken at a distance of 25cm and the rooted plants are transplanted from the polybags. Regular irrigation and weeding are to be carried out. In the second year with the onset of monsoon, seedbeds are again refreshed after adding about 4 tonnes of FYM. At the end of second year tubers are collected. Care should be taken to wear gloves, else the chemical plumbagin present in the roots will cause burning sensation. The collected tubers are washed, tied into bundles and marketed. Plumbago yields about 7-10t tubers/ha with good management (Prasad et al, 1997).... leadwort

Papaya (Carica papaya).

Plant Part Used: Fruit (ripe and unripe), papain enzymes.

Dominican Medicinal Uses: Fruit: eaten for digestive ailments, flatulence, stomachache, intestinal pain, heartburn, heart disease, hypertension, menopausal hot flashes, urinary tract infection, skin infection.

Safety: Ripe fruit is widely consumed and generally considered safe; topical application of the unripe fruit did not show toxicity in rabbits; other plant preparations have shown mixed results in animal toxicity studies.

Contraindications: Pregnancy and lactation (unripe fruit and papain); children under 12 years (due to lack of clinical data); history of hypersensitivity to fruit.

Drug Interactions: Warfarin (w/papain may cause excessive bleeding).

Clinical Data: Human clinical trials: guinea worm infection (leaves), immunomodulation (papain enzymes), burn wound-healing (fruit).

Laboratory & Preclinical Data: In vivo: abortifacient (unripe fruit constituents), anthelmintic (latex), antifertility—inhibits sperm motility (seed extract), antihypertensive (unripe fruit ethanolic extract); anti-ulcer (unripe fruit latex); diuretic (root); reversible azoospermia (seed extract).

In vitro: antiamoebic (seed extract), antihypertensive (unripe fruit ethanolic extract), antimicrobial, antioxidant (unripe fruit and seed), anti-salmonella (leaf and root extracts), immunomodulatory, immunostimulatory (seed extract), uterine stimulatory (fruit latex extract).

* See entry for Lechosa in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.... lechosa

Adhatoda beddomei

Acanthaceae

San:Vasaka, Vasa;

Hin:Adusa; Mal:Chittadalotakam;

Tam:Adutota; Tel:Addasaramu

Importance: Malabar nut or Adhatoda is a large evergreen glabrous perennial shrub, 1.2m in height. It is cultivated for medicinal uses, fencing, manure and as an ornamental plant in pots also. The shrub is the source of the drug vasaka well known in the indigenous systems of medicines for bronchitis. Vasaka leaves, flowers, fruits and roots are extensively used for treating common cold, cough, whooping cough, chronic bronchitis and asthma. It has sedative, expectorant, antispasmodic and anthelmintic actions. The juice of the leaves cures vomiting, thirst, fever, dermatosis, jaundice, phthisis, haematenesis and diseases due to the morbidity of kapha and pitta. The leaf juice is especially used in anaemia and haemorrhage, in traditional medicine. Flowers and leaves are considered efficacious against rheumatic painful swellings and form a good application to scabies and other skin complaints. Many ayurvedic medicines are traditionally prepared out of vasaka like vasarishtam, vasakasavam and vasahareethaki which are effective in various ailments of respiratory system. The drug VASA prepared from this plant forms an ingredient of preparations like Valiya rasnadi kasayam, Chyavanaprasam, Gulgulutiktakam ghrtam, etc. The alkaloid vasicinone isolated from the plant is an ingredient in certain allopathic cough syrups also.

Distribution: Vasaka is distributed all over India upto an altitude of 2000m. This plant grows on wasteland and sometimes it is cultivated also.

Botany: Adhatoda beddomei C.B.Clarke Syn. Justicia beddomei (Clark) Bennet belongs to the family Acanthaceae. This is a large glabrous shrub. Leaves are opposite, ovate, lanceolate and short petioled upto 15cm long, 3.75cm broad, main nerves about 8 pairs. Flowers are white with large bracts, flower heads short, dense or condensed spikes. Fruits are capsules with a long solid base.

Another plant Adhatoda zeylanica Medicus, syn. Adhatoda vasica Nees, Justicia adhatoda Linn. of the same genus is a very closely related plant which is most commonly equated with the drug VASA. This is seen growing wild almost throughout India while A. beddomei is seen more under cultivation. The latter is called Chittadalodakam because of its smaller stature, smaller leaves and flowers.

Agrotechnology: Vasaka is seen almost in all types of climate. It prefers loamy soils with good drainage and high organic content. It can be grown well both in hilly and plain lands. Commercial propagation is by using 15-20cm long terminal cuttings. This is either grown in polybags first, then in the field or planted directly. The plant is cultivated as a pure crop or mixed with plantation crops. The land is ploughed repeatedly to a good tilth and the surface soil is broken upto a depth of 15cm and mixed with fertilizers. The beds are prepared with 1m breadth and 3-4m length. The cuttings are planted during April-May into the beds at a spacing of 30x30cm. FYM is given at 5-10t/ha in the first year. Regular irrigation and weeding are necessary. Harvesting is at the end of second or third year. Roots are collected by digging the seedbeds. Stems are cut 15cm above the root. Stems and roots are usually dried and stored.

Properties and activity: Leaves yield essential oil and an alkaloid vasicine. Roots contain vasicinol and vasicinone. Roots also contain vasicoline, adhatodine, anisotine and vasicolinone. Several alkaloids like quinazoline and valicine are present in this plant.

The plant is bitter, astringent, refrigerant, expectorant, diuretic, antispasmodic, febrifuge, depurative, styptic and tonic. Vasicine is bronchodilator, respiratory stimulant and hypotensive in action, uterine stimulant, uterotonic, abortifacient comparable with oxytocin and methyligin. Uterotonic action of vasicine is mediated through the release of prostaglandins.... malabar nut

Linn. var. piperascens Holmes.

Family: Labiatae; Lamiaceae.

Habitat: Cultivated in Jammu and Kashmir.

English: Japanese Mint.

Unani: Naanaa.

Action: Carminative, chola- gogue, expectorant, antibacterial, antifungal.

Key application: Mint oil— internally for flatulence, functional gastrointestinal and gallbladder disorders; catarrhs of the upper respiratory tract. Externally, for myalgia and neuralgia. (German Commission E.)

Major components of the essential oil are menthol (up to 95%) and men- thone. Others are alpha-and beta- pinene, alpha-thujene, l-limonene, beta-phellandrene, furfural, methyl- cyclohexanone and camphene. The essential oil possesses both antibacterial and antifungal properties.

The leaves show anti-implantation effect. Seeds showed abortifacient activity (29%) in albino rats with marked malformations in neonates where pregnancy was not terminated.... mentha arvensis

Linn.

Family: Nyctaginaceae.

Habitat: North-West Himalayas, Bengal and Manipur.

English: Four-O'Clock Plant, Marvel of Peru.

Ayurvedic: Trisandhi.

Unani: Gul-abbaas.

Siddha/Tamil: Andhimalligai.

Action: Leaf—used for treating uterine discharge; as poultice for abscesses and boils; fresh juice is applied to body in urticaria, also for inflammations and bruises. Tuber— used as a poultice on carbuncles. Root—mild purgative, spasmolytic.

The tuberous roots were erroneously thought to be the source of jalap.

The plant is used for its antitumour and virus-inhibitory activity.

The plant contains triterpenes, al- pha-amyrin and its acetate. Mirabilis Antiviral Protein (MAP) was isolated from the tuberous roots. MAP also showed antiproliferative effect on tumour cells. (MAP is abortifacient.)

Two Mirabilis jalapa antimicrobial proteins, Mj-AMP-1 and Mj-AMP-2, isolated from seeds, showed broad spectrum antifungal actvity involving a number of pathogenic fungi.

Miraxanthins I, II, III and IV, indi- caxanthin and vulgaxanthin have been isolated from flowers.... mirabilis jalapa

(Roxb.) Cogn.

Synonym: M. cymbalaria Fenzl ex Naud.

Family: Cucurbitaceae.

Habitat: Maharashtra and Tamil Nadu, in bushes along the banks of water courses. (It is not cultivated.)

Ayurvedic: Kaarali-Kanda, Kudu- hunchi.

Siddha/Tamil: Athalaikai

Folk: Kakrol (Maharashtra).

Action: Tuberous root—emmena- gogue, abortifacient; acrid; contains a bitter glycoside.... momordica tuberosa

Linn.

Family: Myrsinaceae.

Habitat: Outer Himalayas from Kashmir to Nepal and in Khasi Hills at 300-2,700 m.

Ayurvedic: Vaayavidanga (substitute). (Embelia ribes is the authentic source of Vidanga.)

Folk: Bebrang (Punjab), Kakhum, Shamshaad (according to Unani reference books, Shamshaad is obtained from a Pinaceae tree).

Action: Fruit—anthelmintic (used for the expulsion of tape worms; also as a substitute for Emblia ribes); antispasmodic, purgative; used externally against ringworm and other skin affections. Aerial parts—antifertility, abortifacient. (According to Unani medicine, the fruits of Shamshaad show antifertility activity in females.)

Berries and seeds contain embelic acid and quercitol (1%). Embelin (3%) is present in the dried fruit. Seeds also contain embelin.

Seeds of M. semiserrata Wall. contain embelin (0.4%) and quercitol (0.8%).

Seeds of M. capitellata Wall. contain 1.6% embelin.

These related species are found in Nepal, Bhutan, Assam and North Bengal.... myrsine africana

Linn.

Family: Cucurbitaceae.

Habitat: Cultivated all over India for its fruits.

English: Bitter Gourd, Blsam Pear, Carilla.

Ayurvedic: Kaaravellaka, Kaaravella, Kaathilla, Sushaavi.

Unani: Karelaa.

Siddha/Tamil: Paakal, Paharkai.

Action: Seed/fruit—improves diabetic condition. Fruit—stomachic, laxative, antibilious, emetic, anthelmintic. Used in cough, respiratory diseases, intestinal worms, skin diseases, also for gout and rheumatism. Powdered fruit—applied to wounds and ulcers. Leaf— emetic, antibilious, purgative. Fruit, leaf and root—abortifacient. Leaf and seed—anthelmintic. Root— astringent; appled to haemorrhoids.

Immature fruits gave several nonbitter and bitter momordicosides. Fruits, seeds and tissue culture gave a polypeptide containing amino acids. Fruits also gave 5-hydroxytryptamine, charantin (a steroidal glucoside), dios- genin, cholesterol, lanosterol and beta- sitosterol. Bitter principles are cucur- bitacin glycosides.

Hypoglycaemic effects of the fruit have been demonstrated by blood tests in both humans and animal studies.

Researchers have warned that the fruit extract leads to a false negative test for sugar in the urine (due to its ability to maintain the indicator dye in the glucose oxidase strips and the alkaline copper salts in a reduced state).

Chronic administration of the fruit extract (1.75 g/day for 60 days) to dogs led to testicular lesions with mass atrophy of the spermatogenic elements. The extract reduced the testicular content of RNA, protein and sialic acid as also the acid-phosphatase activity. (Medicinal Plants of India, Vol. 2,1987, Indian Council of Medical Research, New Delhi.)

The fruits and seeds yielded a poly- peptide, p-insulin, which was considered similar to bovine insulin. (Fitoter- apia, 60,1989; Chem Abstr 112,1990.)

The seed and fruit contain an inhibitor of HIV, MAP-30 (Momordi- ca anti-HIV-protein) which exhibited antiviral and antitumour activity in vitro. (Chem Abstr, 113, 1990; ibid, 117, 1992.) Another protein, MRK-29, found in the seed and fruit of a smaller var. of Bitter Gourd found in Thailand, was found to inhibit HIV reverse transcriptase and to increase tumour necrosis factor (TNF). (Planta Med, 67, 2001; Natural Medicines Comprehensive Database, 2007.)

The seeds yield alpha-and beta- momorcharins (glycoproteins). When these glycoproteins were co-cultured with isolated hepatocytes, morphological changes in hepatocytes were observed, indicating hepatotoxicity. Another principle with antilipolytic and lipogenic activities, found along with the alpha-and beta-momorcharin in the seed extract, did not show toxic effect.

Vicine is the hypoglycaemic constituent in the seed. Pure vicine has been found to possess 32.6% hypogly- caemic activity as against 22.2% shown by fresh juice, when tested on albino rats. The vicine is non-haemolytic.

Dosage: Fresh fruit—10-15 ml juice (API, Vol. II); 10-20 ml juice (CCRAS.)... momordica charantia

Linn.

Family: Zygophyllaceae.

Habitat: Throughout Northern and Northwestern India, and in drier regions of Deccan.

English: Wild Rue; Foreign Henna, Syrian Rue.

Ayurvedic: Haramal, Isband.

Siddha/Tamil: Simaiyaravandi, Simaiyalavinai.

Action: Plant—emmenagogue, abortifacient. Seeds—narcotic, hypnotic, antispasmodic, anodyne and emetic; used in asthma, hiccough, colic, neuralgia, hysteria, dysmenorrhoea; used as abortifa- cient (properties similar to ergot, savine and rue). (Dried seeds constitute the drug Harmal of Indian medicine.)

The plant gave flavonoids—kaem- pferol, quercetin and acacetin. Aerial parts and seeds contain alkaloids— harmine, harmaline and harmalol (called harman alkaloids). Harman alkaloids from the seeds have been suggested for use in nervous diseases, and as coronary dilators and embolic. Harmol exhibits hypertensive activity. Harmine, vasicinone, deoxyvasici- none and 8-hydroxy glucosylharmine exhibit antitumour activity.

The alkaloids, harmine, harmaline and harmol exhibit antibacterial and antifungal activity.

The aqueous extract of seeds exhibited significant antiviral activity in vitro against herpes virus hominis type 1, slight activity was also observed against influenza viruses A and B. The plant extract exhibits significant analgesic activity.... peganum harmala

Pineapple (Ananas comosus).

Plant Part Used: Fruit, fruit rind.

Dominican Medicinal Uses: Fruit: juice, taken orally as a diuretic for urinary tract or kidney disorders, cleansing the body internally, for treating bacterial infection, cancer, high blood pressure, high cholesterol, menopausal hot flashes; fruit rind: fermented in sugar and water for internally cleansing and refreshing the body.

Safety: Commonly consumed as food; relatively nontoxic; repeated exposure can cause hypersensitivity.

Contraindications: Caution advised during pregnancy due to possible abortifacient effects of plant steroids.

Drug Interactions: For bromelain (protease enzymes from stem): antibiotics, tetracyclines (elevated drug serum levels), anticoagulants and thrombocyte aggregation inhibitors (increased bleeding).

Laboratory & Preclinical Data: In vivo: antidiabetic, antioxidant, antidyslipidemic (ethanolic leaf extract); antifertility (unripe fruit juice); burn debridement (bromelain—stem enzymes); diuretic (root extract).

In vitro: antitumor (bromelain—stem enzymes).

* See entry for Piña in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.... piña

Linn.

Family: Plumbaginaceae.

Habitat: Cultivated in gardens throughout India; also found wild in Peninsular India.

English: Ceylon Leadwort, Leadwort.

Ayurvedic: Chitraka, Agni, Vahni, Jvalanaakhya, Krshaanu, Hutaasha, Dahana, Sikhi.

Unani: Sheetraj Hindi. Siddha/Tamil: Chittramoolam.

Action: Root—intestinal flora normalizer, stimulates digestive processes; used for dyspepsia. Root paste is applied in order to open abscesses; a paste prepared with milk, vinegar or salt and water, is used externally in leprosy and other obstinate skin diseases. A cold infusion is used for influenza and black-water fever.

Key application: In sprue, malabsorption syndrome, piles and inflammatory diseases of ano-rectum. (The Ayurvedic Pharmacopoeia of India.)

The root yielded naphthoquinone derivatives, plumbagin being the most important active principle.

The root extract, after processing for plumbagin enhancement, has been used in a number of drug formulations for liver ailments. Experimentally, plumbagin prevented the accumulation of triglycerides in liver and aorta and regressed atheromatous plaques and abdominal aorta. The chloroform extract of the root showed significant activity against pencillin-resistant (also non-pencillin resistant) strains of Neisseria gonorrhoea. (The root is used for treating sexually transmitted diseases in traditional Indian medicine.)

In Siddha medicine, in Tamil Nadu, the plant is an ingredient in a number of drug formulations for treating cancers of the uterus, breast, lungs and oral cavity, in addition to haemorrhoids.

Plumbagin is abortifacient, antiovu- latory; causes selective testicular lesions in dogs; in lower doses it behaves like a spindle poison, in higher concentration exhibits radiomimetic nu- cleotoxic and cytotoxic effects.

Dosage: Detoxified root—1-2 g powder. (API, Vol. I.)... plumbago zeylanica

Poir.

Synonym: R. spinosa Poir. R. brandisii Gamble. R. longispina W. & A. R. tomentosa W. & A. non Blume. Xeromphis spinosa Keay.

Habitat: Assam, Naga and Khasi Hills, Travancore and the Andamans.

English: Common Emetic Nut.

Ayurvedic: Madana, Chhardana, Pindi, Shalayaka, Vishapushpaka.

Unani: Mainphal, Jauz-ul-Qai.

Siddha/Tamil: Marukkaaraikai, Madkarai.

Folk: Mainphal.

Action: Fruit—nervine, calmative, antispasmodic, emetic, anthelmintic, abortifacient. Used as a substitute for ipecacuanha.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the dried fruit in chlorosis, common cold, rhinitis and obstinate skin diseases.

The activity of the drug is attributed to the presence of saponins which occur to the extent of 2-3% in fresh fruits and about 10% in dried whole fruit. The saponins are concentrated mostly in the pulp. A mixture of two saponins, viz. randialic or neutral saponin and randialic acid or acid saponin has been isolated from the pulp. On complete hydrolysis both the saponins yield oleanolic acid as sapogenin. Ursosaponin, isolated from the ethanolic extract of the dried whole fruit, gave ursolic acid and glucose. Randianin, isolated from the fruit, gave a haemolytic triterpe- noid saponin.

In experimental animals, the drug caused haemolysis both in vitro and in vivo. Crude saponin fraction showed haemolytic, molluscidal and immuno- stimulating activities.

Oleanolic acid 3-glucoside, isolated from the seed, exhibited anti-arthritic activity in exudative and proliferative phases of inflammation in rats.

Dosage: Fruit—0.5-1.0 g powder for decoction, 3-6 g for induction vomiting. (API, Vol. I.)... randia dumetorum

Benth. ex Kurz.

Family: Apocynaceae.

Habitat: The sub-Himalayas tract from Punjab to Nepal, Sikkim, Bhutan, Assam, Western Ghats and the Andamans.

English: Rauvolfia root, Serpentina Root, Indian Snakeroot.

Ayurvedic: Sarpagandhaa of Ayurvedic texts was not the Sarpagandhaa of modern medicine. (Sarpagandhaa was equated with Naakuli, Sarpach- hatrikaa and Varshaasu Chha- trikaaraa. Sarpagandhaa and Sarpasugandhaa were synonyms of Naakuli.)

Folk: Chhotaa Chaand.

Action: Root—decoction is employed to increase uterine contractions and for expulsion of foetus in difficult cases. The total alkaloidal extract of the root induces bradycardia, hypotension, sedation. It finds application in hypochondria, neuropsychi- atric disorders, psychosis and schizophrenia.

Key application: In mild, essential hypertension (borderline hypertension, especially with elevated tension of the sympathetic nervous system, for example, sinus tachycardia, anxiety, tension and psychomotor irritation, when dietetic measures alone are not sufficient. (German Commission E.)

(Average daily dose: 600 mg drug corresponding to 6 mg total alkaloid.) Treatment is usually administered with a diuretic to prevent fluid retention which may develop if Rauvolfia root is given alone. (WHO.) Contraindicated in depression, bleeding disorders, gastric and duodenal ulcers. (Sharon M. Herr.) Also contraindicated in pregnancy, since it has both teratogenic and abortifacient potential. (Francis Brinker.)

The root and root bark are rich in alkaloids, the most important being reserpine, others, around 30, which include ajmaline, ajmalicine (raubasine), ajmalicine, yohimbine, coryanthine, iso-ajmaline, neo-ajmaline, papaver- ine, raubasine, rauwolscine, rescin- namine, reserpine, sarpagine, serpentine, serpentinine, serpinine and de- serpidine.

Reserpine is hypotensive and tranquilizer, used for certain forms of mental disorders. Ajmalicine (raubasine) and rescinnamine are also hypoten- sive and tranquilizer. Deserpidine is sedative, as well as hypotensive. Aj- maline exhibits antiarrhythmic activity.

A number of Rauvolfia species are found in India: R. beddomei Hook. f.; R. densiflora Benth ex Hook. f. (Himalayas, Khasi and Aka Hills; Western and Eastern Ghats); R. micrantha Hook. f; known as Malabar Rauvolfia, (Kerala, up to an altitude of 300 m)

The roots of R. beddomei contain ajmalicine, sarpagine and serpentine, but no reserpine. R. densiflora yielded 0.51% of total alkaloids (reserpine 0.01%). R. micrantha gave ajmalicine, raunamine, reserpiline, sarpagine, neosarpagine, in addition to reserpine.

(In classical Ayurvedic texts, Nakuli and Gandha-naakuli were included in compound formulations for mental diseases.)... rauvolfia serpentina

(L.) DC.

Family: Papilionaceae.

Habitat: All over plains and in the Himalayas up to 1,200 m.

Folk: Raan-ghevaraa (smaller var.) (Maharashtra); Jhinki, Kammervel (Gujarat); Chittavarai (Tamil Nadu).

Action: Leaves—abortifacient. Seeds—bitter, toxic.

The leaves afforded isovitexin and apigenin derivatives.

Aerial parts gave steroidal glyco- sides, along with ergosterol peroxide, stigmasterol and lupeol; bergapten, isopimpinellin, umbelliferone and beta-sitosterol have also been isolated.

The seed coat and pericarp contained gallic and protocatechuic acid, prodelphinmidine and hydroquinone diacetate and C-glycosyl flavones.

The extract of seeds shows agglutinating activity with certain type of human red blood cells.

R. bracteata Benth. ex Baker (upper Gangetic plains) and R. jacobii Chandra & Shetty (Tirunelveli, Tamil Nadu) contain vitexin, isovitexin, orientin, iso-orientin and apigenin derivatives.... rhynchosia minima

Linn. (European BlackBerry, European Bramble, known as Vilaayati Anchhu) is cultivated in the valley of Kashmir and in Assam and Tamil Nadu up to 2,000 m. A decoction of the root is used for dysentery and whooping cough. The plant gave a triterpenic acid, rubitic acid, characterized as 7 alpha-hydroxyursolic acid.

Key application: Rubus fruticosus leaf—in nonspecific, acute diarrhoea, mild inflammation of the mucosa of oral cavity and throat. (German Commission E.)

Rubus rugosus Sm. synonym R. moluccanus auct non Linn., (known as Kalsol in Kumaon) is found in Central and Eastern tropical and temperate Himalaya from Nepal to Sikkim and in Assam. The plant contains triter- penes, also afforded rubusic acid and beta-sitosterol; leaves gave tormentic acid. Leaves exhibit astringent, emme- nagogue and abortifacient properties.

Rubus niveus Thunb. (Mysore Raspberry, Mahabaleshwar Raspberry) is common in evergreen forests of Ma- habaleshwar.

European Raspberry is equated with Rubus idaeus Linn. The leaves contain flavonoids, mainly glycosides of kaem- pferol, quercetin and tannins. Raspberry leaf tea has been used in Europe to facilitate child birth. Its uterine relaxant effects have been demonstrated in animals (the extract appears to effect only the pregnant uterus, no activity has been observed on the non- pregnant uterus).

The leaves of European Raspberry (Rubus idaeus) and other species exhibit astringent, carminative and spasmolytic activity. Leaves are used for painful and profuse menstruation and, as mentioned earlier, for making parturition easier. An infusion is used for bowel complains, also as a blood purifier. Leaves contain ascorbic acid (about 80 mg/100 g). Polyphenol content of the fruit (methanolic extract) exhibited scavenging and antilipo-peroxidant activities.

Rubus idaeus has been introduced into India and is cultivated on a small scale in South Indian hill stations.

The leaf of Rubus idaeus has been included among unapproved herbs by German Commission E, as its efficacy has not been documented.... rubus fruticosus

Linn.

Family: Rutaceae.

Habitat: Native to Mediterranean region; cultivated all over India.

English: Garden Rue.

Unani: Sudaab, Suddaab.

Siddha/Tamil: Aruvada.

Action: Herb—stimulating, antispasmodic, stomachic; irritant, abortifacient. Used as an emme- nagogue, in hysterical conditions, cough and croupy affections, colic and flatulence. Leaf—used in atonic amenorrhoea, menorrhoea and colic. Externally, used for sciatica, headache, muscular chest pain, bronchitis and arthritic conditions. (Fresh juice of leaves, internally, can lead to painful irritations of the stomach and intestines). Oil— antispasmodic, antiepileptic, em- menagogue, rubefacient. (Toxic in large doses.)

Ruta graveolens has been included among unapproved herbs by German Commission E.

The herb contains a volatile oil, with 2-undecanone (30.73) 2-nona- none (18.06), 2-nonyl acetate (11.03), psoralen (1.28) and bergapten and xan- thotoxin (7.24%); rutin (about 2%). The flavonoids include quercetin; cou- marins include bergapten, daphnore- tin, isoimperatorin, naphthoherniarin, psoralen, pangelin, rutamarin, rutarin, scopoletin and umbelliferone. Tissue culture of the plant gave furacridone alkaloids. Tissue culture of the root gave gravacridondiol and its glucoside.

The spasmolytic activity of the herb is attributed to the presence of bergapten, xanthotoxin and the essential oil. Anti-inflammatory and antitumour activity is due to rutin. The furo- coumarins are responsible for the herb's phototoxicity.

The herb is hepatotoxic, and is con- traindicated in kidney diseases and bleeding disorders. (Sharon M. Herr.) Maximum safe level is 0.001% for Rue and 0.0002% for the oil. (Natural Medicines Comprehensive Database, 2007.)... ruta graveolens

Abortion is a medical procedure of ending a pregnancy during its first 24 weeks. There are several reasons why this medical process is carried out: a fetus’ or woman’s health issue or, most frequent, there are personal considerations which impede the woman to keep the baby. No matter the reasons of an abortion, it should be made by a physician. Also, the woman’s post-abortion state requires medical observation, because there have been acknowledged physical and psychological effects after this medical condition. Like any other medical procedure, abortion implies risks, like losing a large amount of blood (haemorrhage) or inflammation of the pelvis. Studies revealed that further miscarriages can be associated with earlier abortions, as the surgery may lead to the damage of the womb. A pregnancy can be ended by a medical procedure or, by a traditional method, like drinking teas causing abortion. How Tea for Abortion works There are two categories of tea which lead to ending a pregnancy: emmenagogue and abortifacient teas. The first type of tea induces woman’s period to start, whereas the second one causes painful contractions of the uterus, followed by abortion. Teas leading to Abortion Please read the list of some of the teas you should not drink if you are pregnant or, you try to become pregnant. Blue Cohosh is a wood plant, growing in New England (United States) and also in Canada. It has anti-inflammatory and antispasmodic properties. It is generally used to treat rheumatism and to prevent osteoporosis. Muscles aches caused by physical effort are relieved by taking Blue Cohosh as tea, tincture or decoction. It cannot stimulate the estrogen production thus, the body is not able to provide the endometrial and uterine growth, leading to contractions of the uterine and, finally, to a painful abortion. Unfortunately, Blue Cohosh tea has been used for a long period of time as a medicinal and home-made beverage for abortion. Pennyroyal is a plant from the mint family, whose essential oil is toxic if taken internally. In the past, women were poisoning themselves in the attempt of ending the pregnancy. Taken as an infusion, the plant is efficient in mitigating the unpleasant feelings of the upset stomach, abdominal cramps , as well as colds. Pennyroyal tea should not be drunk by pregnant women or by those who want to become pregnant, because it irritates the uterus, causing contractions and, of course, abortion. Tansy is a herbaceous plant, originating from Europe, but also cultivated in the United States. It is best known for its action as an insect repellant, being used as treatment against worms. It is a digestion adjuvant as well as a migraine reliever. Tansy tea provides contractions of the uterus and abortion, which can be so violent that causes death, just like the above mentioned teas causing abortion. Uterine bleeding, nausea and loss of consciousness are some of the signs displayed by people who had ingested a large dose of the beverage. Women should bear in mind that these three types of tea are scientifically proven to cause abortion. So, they should not consume them! Furthermore, women should ask their doctor for a list of the edible products while pregnancy, in order to avoid unpleasant situations of any kind.  ... teas causing abortion

Buch.-Ham ex G. Don.

Synonym: T. pentandra auct. non Linn.

Family: Aizoaceae.

Habitat: The plains from Punjab to Bihar, extending southwards to Karnataka.

Ayurvedic: Varshaabhu (related species).

Action: Plant—astringent in stomach diseases, deobstruent, abortifacient.

The root and stems contain hentri- acontane, hentriacontanol, beta-sitos- terol glucoside, stigmasterol glucoside and nonacos-1-en-4-one.... trianthema govindia

Linn.

Synonym: W. americana Linn.

Family: Sterculiaceae.

Habitat: Tropical regions of India.

Siddha/Tamil: Shembudu.

Folk: Khar-Duudhi (Bengal).

Action: Plant—emollient, bechic, febrifuge, purgative, abortifacient. Root—prescribed in internal haemorrhages.

The plant yields pelargonidin and cyanidin glycoside and apigeninidin. Anthocyanins were also detected. The alkaloid, adouetin-7 sulfamate, induced hypothermia and sedation at low levels and hyperexcitability at high levels.

A decoction of roots possesses anti- syphlitic property.... waltheria indica

Barbados aloes, Cape aloes, Socotrine aloes. Curacao, Aloe barbadensis Mill., Aloe Ferox Mill., Aloe perryi Baker. German: Aloe?. French: Aloe?s. Italian: Aloe?. Spanish: Aloe, Linaloe. Chinese: Chin-hiang. Liquid from cut leaves allowed to dry solid. Contains anthraquinone glycosides (aloin), resins.

Action: emmenagogue, abortifacient, vermifuge. Perhaps the best known laxative of history. Stimulates peristalsis. Stool softener.

Uses: chronic constipation, with a carminative to prevent griping. Said to have anti-malignant activity. An ingredient of the Natural Health Tablet.

Dose. Barbados aloes: 50mg (MD). Cape aloes: 100mg (MD). Aloin: 20mg (MD). Tincture Aloes BPC 1949. Dose: 2-8ml. ... aloes

Gossypium herbaceum L. German: Baumwollenbaum. French: Cotonnier en arbre. Italian: Cotone arbusto. Arabian: Kuttun. Indian: Karpas. Iranian: Pambah. Dried root bark. Cotton fibre leaves.

Constituents: mucilage, flavonoids, fixed oil, resin, tannin.

Action: abortifacient. Parturient. Traditional male contraceptive (unproven). Oxytocic, (fresh gathered). Uses. For procuring abortion. Claimed to contract the womb after the action of Ergot, but safer. Alabama Indian squaws made a tea of the freshly-gathered roots to ease pains of childbirth. For absent or painful menstruation. Pain in ovaries. Morning sickness. Reduces sperm count and sexual urge in the male. Reference. Rats were made temporarily infertile without change of mating behaviour, without reducing the male hormone (testosterone) and without heart abnormalities. (Dr Yun-feng-Ren, People’s Republic of China)

Not used in pregnancy. Hypokalaemia may follow overdose. Preparations. Liquid Extract, BPC (1934). Dose, 2-4ml. Tincture BPC (1934). Dose 30-60 drops. ... cotton root

Juniperus virginiana

FAMILY: Cupressaceae

SYNONYMS: Red cedar, eastern red cedar, southern red cedar, Bedford cedarwood (oil).

GENERAL DESCRIPTION: A coniferous, slow-growing, evergreen tree up to 33 metres high with a narrow, dense and pyramidal crown, a reddish heartwood and brown cones. The tree can attain a majestic stature with a trunk diameter of over 1.5 metres.

DISTRIBUTION: Native to North America, especially mountainous regions east of the Rocky Mountains.

OTHER SPECIES: There are many cultivars of the red cedar; its European relative is the shrubby red cedar (J. sabina) also known as savin – see entry. It is also closely related to the East African cedarwood (J. procera).

HERBAL/FOLK TRADITION: The North American Indians used it for respiratory infections, especially those involving an excess of catarrh. Decoctions of leaves, bark, twigs and fruit were used to treat a variety of ailments: menstrual delay, rheumatism, arthritis, skin rashes, venereal warts, gonorrhoea, pyelitis and kidney infections.

It is an excellent insect and vermin repellent (mosquitoes, moths, woodworm, rats, etc.) and was once used with citronella as a commercial insecticide.

ACTIONS: Abortifacient, antiseborrhoeic, antiseptic (pulmonary, genito-urinary), antispasmodic, astringent, balsamic, diuretic, emmenagogue, expectorant, insecticide, sedative (nervous), stimulant (circulatory).

EXTRACTION: Essential oil by steam distillation from the timber waste, sawdust, shavings, etc. (At one time a superior oil was distilled from the red heartwood, from trees over twenty five years old.)

CHARACTERISTICS: A pale yellow or orange oily liquid with a mild, sweet-balsamic, ‘pencil wood’ scent. It blends well with sandalwood, rose, juniper, cypress, vetiver, patchouli and benzoin.

PRINCIPAL CONSTITUENTS: Mainly cedrene (up to 80 per cent), cedrol (3–14 per cent), and cedrenol, among others.

SAFETY DATA: Externally the oil is relatively non-toxic; can cause acute local irritation and possible sensitization in some individuals. Use in dilution only with care, in moderation. ‘The oil is a powerful abortifacient … use of the oil has been fatal.’. Avoid during pregnancy. Generally safer to use Atlas cedarwood.

AROMATHERAPY/HOME: USE

Skin Care: Acne, dandruff, eczema, greasy hair, insect repellent, oily skin, psoriasis.

Circulation, Muscles And Joints: Arthritis, rheumatism.

Respiratory System: Bronchitis, catarrh, congestion, coughs, sinusitis.

Genito-Urinary System: Cystitis, leucorrhoea.

Nervous System: Nervous tension and stress-related disorders.

OTHER USES: Extensively used in room sprays and household insect repellents. Employed as a fragrance component in soaps, cosmetics and perfumes. Used as the starting material for the isolation of cedrene.... cedarwood, virginian

National Institute of Medical Herbalists.

1. It is illegal for anyone not a registered medical practitioner to attempt to procure an abortion: a member must not knowingly administer an abortifacient or known uterine muscle stimulant remedies to a pregnant patient, nor instruments for the purpose of procuring an abortion, nor assist in any illegal operation.

2. It is required that any intimate examinations on a patient of the opposite sex be conducted in the presence of a relative of the patient or a suitable assistant.

3. A member must not treat or prescribe any remedy for gonorrhoea, syphilis, or urinary affections of a venereal nature.

4. It is the duty of the practitioner to notify the District Medical Officer regarding any disease on the current list of notifiable diseases. In cases of industrial poisoning or accident the local district branch of the Health and Safety Executive should be notified.

5. A member must consider very carefully the implications of recommending a course of treatment contrary to the advice of the patient’s registered medical practitioner or of not recommending referral to a registered medical practitioner in the case of serious disease or uncertain diagnosis. Members must be aware of their vulnerability in law on this issue and must ensure in such a case that all available information is given to the patient and that the patient makes the final decision without coercion.

6. A parent or supervising adult must be present at any treatment or examination of a child under the age of 16, or of a mentally-retarded patient.

7. The Data Protection Act means that any practitioner keeping patient’s data on computer file must register under the terms of the Act.

8. A member must become familiar with the terms of the Medicine’s Act 1968 and subsequent statutory instruments, notably the Medicines (Retail Sale or Supply of Herbal Remedies) Order 1977. Particular care should be taken to become familiar with the statutory maximum doses of those remedies listed in Schedule III of the latter order. Detailed records of prescriptions and dispensing must also be kept.

9. The Medicines Act further states that to claim exemptions from the restrictions on the supply of certain herbal remedies, the practitioner should supply said remedies from premises occupied by the practitioner and able to be closed so as to exclude the public.

10. The Medicines Act adds that to claim the said exemptions, the person supplying the remedy “sells or supplies it for administration to a particular person after being requested by or on behalf of that person and in that person’s presence to use his own judgement as to the treatment required”. The member should avoid treatment through telephone or postal contact, although repeat prescriptions may be supplied on this basis for a limited period.

11. Dispensing and labelling of medicines should at least comply with the terms of the Medicines Act. All medicines should be labelled to clearly indicate the correct dosage or other directions for use (especially for those remedies subject to a statutory maximum dose), and with the name and address of the practitioner and the date of dispensing.

12. A member should never claim verbally or in print to be able to cure any life-threatening or serious disease.

13. The distribution or display of letter headings, business cards or practice information should be compatible with the highest professional medical standards. ... code of practice

Pilocarpus jaborandi

FAMILY: Rutaceae

SYNONYMS: Pernambuco jaborandi, P. pennatifolius, iaborandi, jamborandi, arrudo do mato, arruda brava, jamguaraddi, juarandi.

GENERAL DESCRIPTION: A woody shrub up to 2 metres high with a smooth, greyish bark, large brownish-green leathery leaves containing big oil glands and reddish-purple flowers.

DISTRIBUTION: Native to Brazil; other species are found in Paraguay, Cuba, the West Indies and Central America.

OTHER SPECIES: There are many members of the Rutaceae and Piperaceae family known simply as jaborandi, such as Piper jaborandi. Others include maranham jaborandi (P. microphyllus), ceara jaborandi (P. trachylophus) and aracti jaborandi (P. spicatus).There is consequently some confusion about the exact botanical source of the oil.

HERBAL/FOLK TRADITION: Jaborandi induces salivation and most gland secretions; it was also used at one time to promote hair growth. ‘Useful in psoriasis, prurigo, deafness ... chronic catarrh, tonsillitis and particularly dropsy.’ .

ACTIONS: Antiseptic, diaphoretic, emmenagogue, galactagogue, stimulant (nerve).

EXTRACTION: Essential oil by steam distillation from the dried leaflets.

CHARACTERISTICS: An orange or yellow liquid with a sweet-herbaceous fruity odour.

PRINCIPAL CONSTITUENTS: Pilocarpine is the main active constituent; also isopilocarpine, pilocarpidine, methyl nonyl ketone, dipentene and other hydrocarbons.

SAFETY DATA: Oral toxin, skin irritant, abortifacient.

AROMATHERAPY/HOME: USE None.

OTHER USES: Various hypodermic solutions are prepared from pilocarpine: the crude oil is rarely used. Little used in perfumery or flavour work due to toxicity.... jaborandi

Juniperus communis

FAMILY: Cupressaceae

SYNONYM: Common juniper.

GENERAL DESCRIPTION: An evergreen shrub or tree up to 6 metres high, with bluish green narrow stiff needles. It has small flowers and little round berries, which are green in the first year, turning black in the second and third.

DISTRIBUTION: Native to the northern hemisphere: Scandinavia, Siberia, Canada, northern Europe and northern Asia. The oil is mainly produced in Italy, France, Yugoslavia, Austria, Czechoslovakia, Spain, Germany and Canada.

OTHER SPECIES: In Yugoslavia an oil is produced from the fruit and twigs of J. smerka, less rich and sweet than that of common juniper. There are various other species of juniper such as J. oxycedrus which produces cade oil, J. virginiana which produces the so-called Virginian cedarwood oil, and J. sabina which produces savin oil. See also Botanical Classification section.

HERBAL/FOLK TRADITION: The needles and berries have a long traditional history of use. It is used medicinally for urinary infections such as cystitis and urethritis; for respiratory problems such as bronchitis, colic and coughs; as well as gastro-intestinal infections and worms. It helps expel the build-up of uric acid in the joints, and is employed in gout, rheumatism and arthritis. Current in the British Herbal Pharmacopoeia for rheumatic pain and cystitis.

ACTIONS: Antirheumatic, antiseptic, antispasmodic, antitoxic, aphrodisiac, astringent, carminative, cicatrisant, depurative, diuretic, emmenagogue, nervine, parasiticide, rubefacient, sedative, stomachic, sudorific, tonic, vulnerary.

EXTRACTION: Essential oil by steam distillation from 1. the berries (sometimes fermented first as a by-product of juniper – brandy manufacture – the oil is considered an inferior product), and 2. the needles and wood. A resinoid, concrete and absolute are also produced on a small scale.

CHARACTERISTICS: 1. A water-white or pale yellow mobile liquid with a sweet, fresh, woody-balsamic odour. It blends well with vetiver, sandalwood, cedarwood, mastic, oakmoss, galbanum, elemi, cypress, clary sage, pine, lavender, lavandin, labdanum, fir needle, rosemary, benzoin, balsam tolu, geranium and citrus oils. 2. A water-white or pale yellow mobile liquid with a sweet-balsamic, fresh, turpentine-like odour.

PRINCIPAL CONSTITUENTS: Mainly monoterpenes: pinene, myrcene, sabinene with limonene, cymene, terpinene, thujene and camphene, among others.

SAFETY DATA: Non-sensitizing, may be slightly irritating, generally non-toxic. However, it stimulates the uterine muscle (an abortifacient) and must not be used during pregnancy. Neither should it be used by those with kidney disease due to its nephrotoxic effect. The wood oil is usually adulterated with turpentine oil. It is best to use only juniper berry oil, in moderation.

AROMATHERAPY/HOME: USE

Skin care: Acne, dermatitis, eczema, hair loss, haemorrhoids, oily complexions, as a skin toner, wounds.

Circulation muscles and joints: Accumulation of toxins, arteriosclerosis, cellulitis, gout, obesity, rheumatism.

Immune system: Colds, ’flu, infections.

Genito-urinary system: Amenorrhoea, cystitis, dysmenorrhoea, leucorrhoea.

Nervous system: Anxiety, nervous tension and stress-related conditions.

OTHER USES: Berries and extracts are used in diuretic and laxative preparations; also veterinary preventatives of ticks and fleas. Employed as a fragrance component in soaps, detergents, cosmetics and perfumes, especially spicy fragrances and aftershaves. Extensively used in many food products but especially alcoholic and soft drinks: the berries are used to flavour gin.... juniper

Artemisia vulgaris

FAMILY: Asteraceae (Compositae)

SYNONYMS: Armoise, wild wormwood, felon herb, St John’s plant.

GENERAL DESCRIPTION: An erect, much-branched, perennial herb up to 1.5 metres high, with purplish stems, dark green divided leaves which are downy white beneath, and numerous small reddish-brown or yellow flowers.

DISTRIBUTION: Believed to have originated in eastern Europe and western Asia; now found in temperate zones all over the world. The oil is produced in southern France, Morocco, Germany, Hungary, India, China and Japan.

OTHER SPECIES: There are many different species in the Artemisia group (see Botanical Classification), which includes wormwood and tarragon. There are also several different types of mugwort such as the great mugwort (A. arborescens) and the Chinese mugwort (A. moxa and A. sinensis) which are both used to make ‘moxa’ in Japan, containing mainly borneol.

HERBAL/FOLK TRADITION: In Europe, the herb has been associated with superstition and witchcraft, and was seen as a protective charm against evil and danger. It is said that St John the Baptist wore a girdle of the leaves in the wilderness. It was also seen as a woman’s plant, used as a womb tonic, for painful or delayed menstruation and as a treatment for hysteria and epilepsy. It was also used to expel worms, control fever and as a digestive remedy.

In the East the white fluffy underside of the leaves is used for moxibustion, a process often combined with acupuncture, in which the compressed dried herb is burned over a certain point in the body to stimulate it with heat. Moxa was also used in Europe to relieve gout and rheumatism. It is current in the British Herbal Pharmacopoeia as a specific for amenorrhoea and dysmenorrhoea.

ACTIONS: Anthelmintic, antispasmodic, carminative, choleretic, diaphoretic, diuretic, emmenagogue, nervine, orexigenic, stimulant, stomachic, tonic (uterine, womb), vermifuge.

EXTRACTION: Essential oil by steam distillation from the leaves and flowering tops.

CHARACTERISTICS: A colourless or pale yellow liquid with a powerful camphoraceous, bitter-sweet, herbaceous odour. It blends well with oakmoss, patchouli, rosemary, lavandin, pine, sage, clary sage and cedarwood.

PRINCIPAL CONSTITUENTS: Thujone, cineol, pinenes and dihydromatricaria ester, among others.

SAFETY DATA: Oral toxin, due to high thujone content. Abortifacient.

AROMATHERAPY/HOME: USE None. ‘It should not be used in therapy either internally or externally.’.

OTHER USES: Used as a fragrance component in soaps, colognes and perfumes. Limited use in flavouring due to toxic levels of thujone.... mugwort

Mentha pulegium

FAMILY: Lamiaceae (Labiatae)

SYNONYMS: Pulegium, European pennyroyal, pudding grass.

GENERAL DESCRIPTION: A perennial herb up to 50 cms tall with smooth roundish stalks, small, pale purple flowers and very aromatic, grey-green, oval leaves. Like other members of the mint family, it has a fibrous creeping root.

DISTRIBUTION: Native to Europe and parts of Asia; it is cultivated mainly in southern Spain, Morocco, Tunisia, Portugal, Italy, Yugoslavia and Turkey.

OTHER SPECIES: There are several different varieties of pennyroyal according to location: in Britain the ‘erecta’ and ‘decumbens’ types are most common. The North American pennyroyal (Hedeoma pulegoides), which is also used to produce an essential oil, belongs to a slightly different species, though it shares similar properties with the European variety.

HERBAL/FOLK TRADITION: A herbal remedy of ancient repute, used for a wide variety of ailments. It was believed to purify the blood and also be able to communicate its purifying qualities to water. ‘Pennyroyal water was distilled from the leaves and given as an antidote to spasmodic, nervous and hysterical affections. It was also used against cold and “affections of the joints”.’.

It is still current in the British Herbal Pharmacopoeia, indicated for flatulent dyspepsia, intestinal colic, the common cold, delayed menstruation, cutaneous eruptions and gout.

ACTIONS: Antiseptic, antispasmodic, diaphoretic, carminative, digestive, emmenagogue, insect repellent, refrigerant, stimulant.

EXTRACTION: Essential oil by steam distillation from the fresh or slightly dried herb.

CHARACTERISTICS: A colourless or pale yellow liquid with a very fresh, minty herbaceous odour. It blends well with geranium, rosemary, lavandin, sage and citronella.

PRINCIPAL CONSTITUENTS: Mainly pulegone, with menthone, iso-menthone, octanol, piperitenone and trans-iso-pulegone. Constituents vary according to source – the Moroccan oil contains up to 96 per cent pulegone.

SAFETY DATA: Oral toxin. Abortifacient (due to pulegone content). Ingestion of large doses has resulted in death.

AROMATHERAPY/HOME: USE None. ‘Should not be used in aromatherapy whether internally or externally.’.

OTHER USES: Used as a fragrance material mainly in detergents or low-cost industrial perfumes. Mainly employed as a source of natural pulegone.... pennyroyal

Ruta graveolens

FAMILY: Rutaceae

SYNONYMS: Garden rue, herb-of-grace, herbygrass.

GENERAL DESCRIPTION: An ornamental, shrubby herb with tough, woody branches, small, smooth, bluish-green leaves and greeny yellow flowers. The whole plant has a strong, aromatic, bitter or acrid scent.

DISTRIBUTION: Native to the Mediterranean region; found growing wild extensively in Spain, Morocco, Corsica, Sardinia and Algeria. It is cultivated mainly in France and Spain for its oil; also in Italy and Yugoslavia.

OTHER SPECIES: There are several different types of rue, such as the summer rue (R. montana), winter rue (R.chalepensis) and Sardinian rue (R. angustifolia), which are also used to produce essential oils.

HERBAL/FOLK TRADITION: A favoured remedy of the ancients, especially as an antidote to poison. It was seen as a magic herb by many cultures and as a protection against evil. It was also used for nervous afflictions. ‘It helps disorders in the head, nerves and womb, convulsions and hysteric fits, the colic, weakness of the stomach and bowels; it resists poison and cures venomous bites.’.

ACTIONS: Antitoxic, antitussive, antiseptic, antispasmodic, diuretic, emmenagogue, insecticidal, nervine, rubefacient, stimulant, tonic, vermifuge.

EXTRACTION: Essential oil by steam distillation from the fresh herb.

CHARACTERISTICS: A yellow or orange viscous mass which generally solidifies at room temperature, with a sharp, herbaceous-fruity acrid odour. The winter rue oil does not solidify at room temperature.

PRINCIPAL CONSTITUENTS: Mainly methyl nonyl ketone (90 per cent in summer rue oil).

SAFETY DATA: Oral toxin (due to main constituent). Skin and mucous membrane irritant. Abortifacient. ‘Rue oil should never be used in perfumery or flavour work.’ .

AROMATHERAPY/HOME: USE None. ‘Should not be used at all in aromatherapy.’.

OTHER USES: Employed as a source of methyl nonyl ketone.... rue

Salvia officinalis

FAMILY: Lamiaceae (Labiatae)

SYNONYMS: Garden sage, true sage, Dalmatian sage.

GENERAL DESCRIPTION: An evergreen, shrubby, perennial herb up to 80 cms high with a woody base, soft, silver, oval leaves and a mass of deep blue or violet flowers.

DISTRIBUTION: Native to the Mediterranean region; cultivated worldwide especially in Albania, Yugoslavia, Greece, Italy, Turkey, France, China and the USA.

OTHER SPECIES: There are several different species and cultivars which have been developed, such as the Mexican sage (S. azurea grandiflora) and the red sage (S. colorata) both of which are used medicinally. Essential oils are also produced from other species including the Spanish sage (S. lavendulaefolia) and clary sage (S. selarea) – see separate entries and Botanical Classification section.

HERBAL/FOLK TRADITION: A herb of ancient repute, valued as a culinary and medicinal plant – called herba sacra or ‘sacred herb’ by the Romans. It has been used for a variety of disorders including respiratory infections, menstrual difficulties and digestive complaints. It was also believed to strengthen the senses and the memory.

It is still current in the British Herbal Pharmacopoeia as a specific for inflammations of the mouth, tongue and throat.

ACTIONS: Anti-inflammatory, antimicrobial, anti-oxidant, antiseptic, antispasmodic, astringent, digestive, diuretic, emmenagogue, febrifuge, hypertensive, insecticidal, laxative, stomachic, tonic.

EXTRACTION: Essential oil by steam distillation from the dried leaves. (A so-called ‘oleoresin’ is also produced from the exhausted plant material.)

CHARACTERISTICS: A pale yellow mobile liquid with a fresh, warm-spicy, herbaceous, somewhat camphoraceous odour. It blends well with lavandin, rosemary, rosewood, lavender, hyssop, lemon and other citrus oils. The common sage oil is preferred in perfumery work to the Spanish sage oil which, although safer, has a less refined fragrance.

PRINCIPAL CONSTITUENTS: Thujone (about 42 per cent), cineol, borneol, caryophyllene and other terpenes.

SAFETY DATA: Oral toxin (due to thujone). Abortifacient; avoid in pregnancy. Avoid in epilepsy. Use with care or avoid in therapeutic work altogether – Spanish sage or clary sage are good alternatives.

AROMATHERAPY/HOME: USE None.

OTHER USES: Used in some pharmaceutical preparations such as mouthwashes, gargles, toothpastes, etc. Employed as a fragrance component in soaps, shampoos, detergents, anti-perspirants, colognes and perfumes, especially men’s fragrances. The oil and oleoresin are extensively used for flavouring foods (mainly meat products), soft drinks and alcoholic beverages, especially vermouth. It also serves as a source of natural anti-oxidants.... sage, common

Sassafras albidum

FAMILY: Lauraceae

SYNONYMS: S. officinale, Laurus sassafras, S. variifolium, common sassafras, North American sassafras, sassafrax.

GENERAL DESCRIPTION: A deciduous tree up to 40 metres high with many slender branches, a soft and spongy orange-brown bark and small yellowy-green flowers. The bark and wood are aromatic.

DISTRIBUTION: Native to eastern parts of the USA; the oil is mainly produced from Florida to Canada and in Mexico.

OTHER SPECIES: There are several other species, notably the Brazilian sassafras (Ocotea pretiosa) which is also used to produce an essential oil (also highly toxic). See also Botanical Classification section.

HERBAL/FOLK TRADITION: It has been used for treating high blood pressure, rheumatism, arthritis, gout, menstrual and kidney problems, and for skin complaints. ‘Sassafras pith – used as a demulcent, especially for inflammation of the eyes, and as a soothing drink in catarrhal affection.’. The wood and bark yield a bright yellow dye.

ACTIONS: Antiviral, diaphoretic, diuretic, carminative, pediculicide (destroys lice), stimulant.

EXTRACTION: Essential oil by steam distillation from the dried root bark chips.

CHARACTERISTICS: A yellowy-brown, oily liquid with a fresh, sweet-spicy, woody camphoraceous odour. (A safrol-free sassafras oil is produced by alcohol extraction.)

PRINCIPAL CONSTITUENTS: Safrole (80–90 per cent), pinenes, phellandrenes, asarone, camphor, thujone, myristicin and menthane, among others.

SAFETY DATA: Highly toxic – ingestion of even small amounts has been known to cause death. Carcinogen. Irritant. Abortifacient.

AROMATHERAPY/HOME: USE None. ‘Should not be used in therapy, whether internally or externally.’.

OTHER USES: Sassafras oil and crude are banned from food use; safrol-free extract is used to a limited extent in flavouring work. Safrol is used as a starting material for the fragrance item ‘heliotropin’.... sassafras

Juniperus sabina

FAMILY: Cupressaceae

SYNONYMS: Sabina cacumina, savin (oil).

GENERAL DESCRIPTION: A compact evergreen shrub about 1 metre high (though much taller in the Mediterranean countries), which tends to spread horizontally. It has a pale green bark becoming rough with age, small, dark green leaves and purplish-black berries containing three seeds.

DISTRIBUTION: Native to North America, middle and southern Europe. The oil is produced mainly in Austria (the Tirol), a little in France and Yugoslavia.

OTHER SPECIES: Closely related to the common juniper (J. communis) and other members of the family – see juniper.

HERBAL/FOLK TRADITION: It was used at one time as an ointment or dressing for blisters, in order to promote discharge, and for syphilitic warts and other skin problems. It is rarely administered nowadays because of its possible toxic effects.

ACTIONS: Powerful emmenagogue, rubefacient, stimulant.

EXTRACTION: Essential oil by steam distillation from the twigs and leaves.

CHARACTERISTICS: A pale yellow or olive oily liquid with a disagreeable, bitter, turpentine-like odour.

PRINCIPAL CONSTITUENTS: Sabinol, sabinyl acetate, terpinene, pinene, sabinene, decyl aldehyde, citronellol, geraniol, cadinene and dihydrocuminyl alcohol.

SAFETY DATA: Oral toxin. Dermal irritant. Abortifacient. ‘The oil is banned from sale to the public in many countries due to its toxic effects (nerve poison and blood circulation stimulant).’.

AROMATHERAPY/HOME: USE None. ‘Should not be used in therapy, whether internally or externally.’.

OTHER USES: Occasional perfumery use. Little employed nowadays.... savine

Tanacetum vulgare

FAMILY: Asteraceae (Compositae)

SYNONYMS: Chrysanthemum vulgare, C. tanacetum, buttons, bitter buttons, bachelor’s buttons, scented fern, cheese.

GENERAL DESCRIPTION: A hardy perennial wayside herb, up to 1 metre high with a smooth stem, dark ferny leaves and small, round, brilliant yellow flowers borne in clusters. The whole plant is strongly scented.

DISTRIBUTION: Native to central Europe; naturalized in North America and now found in most temperate regions of the world. The essential oil is mainly produced in France, Germany, Hungary, Poland and the USA.

OTHER SPECIES: Closely related to the medicinal herb feverfew (Tanacetum parthenium), the marigolds and daisy family.

HERBAL/FOLK TRADITION: Traditionally used to flavour eggs and omelettes. It has a long history of medicinal use, especially among gypsies, and is regarded as something of a ‘cure all’. It was used to expel worms, to treat colds and fever, prevent possible miscarriage and ease dyspepsia and cramping pains. Externally, the distilled water was used to keep the complexion pale, and the bruised leaves employed as a remedy for scabies, bruises, sprains and rheumatism. It was also used generally for nervous disorders and to keep flies and vermin away.

The flowers are still current in the British Herbal Pharmacopoeia as a specific (used externally) for worms in children.

ACTIONS: Anthelmintic, anti-inflammatory, antispasmodic, carminative, diaphoretic, digestive, emmenagogue, febrifuge, nervine, stimulant, tonic, vermifuge.

EXTRACTION: Essential oil by steam distillation from the whole herb (aerial parts).

CHARACTERISTICS: A yellow, olive or orange liquid (darkening with age) with a warm, sharp spicy herbaceous odour.

PRINCIPAL CONSTITUENTS: Thujone (66–81 per cent), camphor, borneol, among others.

SAFETY DATA: Oral toxin – poisonous due to high thujone content. Abortifacient.

AROMATHERAPY/HOME: USE None. ‘Should not be used in aromatherapy whether internally or externally.’.

OTHER USES: Occasionally used in herbaceous-type perfumes. The oil used to be used in alcoholic drinks – it is no longer used for flavouring.... tansy

Thuja occidentalis

FAMILY: Cupressaceae

SYNONYMS: Swamp cedar, white cedar, northern white cedar, eastern white cedar, tree of life, American arborvitae, cedarleaf (oil).

GENERAL DESCRIPTION: A graceful pyramid-shaped coniferous tree up to 20 metres high with scale-like leaves and broadly-winged seeds, sometimes planted as hedging. The tree must be at least fifteen years old before it is ready to be used for essential oil production.

DISTRIBUTION: Native to north eastern North America; cultivated in France. The oil is produced mainly in Canada and the USA, similar oils are also produced in the East – see here.

OTHER SPECIES: There are many forms and cultivated varieties of this tree: the western red cedar or Washington cedar (T. plicata); the Chinese or Japanese cedar (T. orientalis or Biota orientalis); the North African variety (T. articulata) which yields a resin known as ‘sanderac’.

The hiba tree (Thujopsis dolobrata) is used to produce hiba wood oil and hiba leaf oil in Japan. Hiba wood oil, according to available data, is non-toxic, non-irritant and non-sensitizing (unlike the other thuja oils), and has excellent resistance to fungi and bacteria due to the ketonic substances found in the oil. It is used extensively in Japan as an industrial perfume.

HERBAL/FOLK TRADITION: Used as an incense by ancient civilizations for ritual purposes. A decoction of leaves has been used for coughs, fever, intestinal parasites, cystitis and venereal diseases. The ointment has been used for rheumatism, gout, warts, verrucae, psoriasis and other ailments.

The twigs are current in the British Herbal Pharmacopoeia, used specifically for bronchitis with cardiac weakness, and warts.

ACTIONS: Antirheumatic, astringent, diuretic, emmenagogue, expectorant, insect repellent, rubefacient, stimulant (nerve, uterus and heart muscles), tonic, vermifuge.

EXTRACTION: Essential oil by steam distillation from the fresh leaves, twigs and bark.

CHARACTERISTICS: A colourless to pale yellowy-green liquid with a sharp, fresh, camphoraceous odour.

PRINCIPAL CONSTITUENTS: Thujone (approx. 60 per cent), fenchone, camphor, sabinene and pinene, among others.

SAFETY DATA: Oral toxin – poisonous due to high thujone content. Abortifacient.

AROMATHERAPY/HOME: USE None. ‘Should not be used in aromatherapy either internally or externally.’.

OTHER USES: Used in pharmaceutical products such as disinfectants and sprays; also as a counter-irritant in analgesic ointments and liniments. A fragrance component in some toiletries and perfumes. Employed as a flavour ingredient in most major food categories (provided that the finished food is recognized thujone-free).... thuja

Artemisia absinthium

FAMILY: Asteraceae (Compositae)

SYNONYMS: Common wormwood, green ginger, armoise, absinthium (oil).

GENERAL DESCRIPTION: A perennial herb up to 1.5 metres high with a whitish stem, silvery-green, divided leaves covered in silky fine hairs, and pale yellow flowers.

DISTRIBUTION: Native to Europe, North Africa and western Asia; naturalized in North America. It is extensively cultivated in central and southern Europe, the USSR, North Africa and the USA, where the oil is mainly produced.

OTHER SPECIES: There are many other Artemisia species such as davana and the Roman wormwood. See also entry on mugwort (A. vulgaris) also commonly called ‘armoise’; remedy for epilepsy and as an aromatic stewing herb to banish fleas.

HERBAL/FOLK TRADITION: Used as an aromatic-bitter for anorexia, as a digestive tonic and as a choleretic for liver and gall bladder disorders, usually in the form of a dilute extract. It is also used to promote menstruation, reduce fever and expel worms. It was once used as a remedy for epilepsy and as an aromatic stewing herb to banish fleas.

ACTIONS: Anthelmintic, choleretic, deodorant, emmenagogue, febrifuge, insect repellent, narcotic, stimulant (digestive), tonic, vermifuge.

EXTRACTION: Essential oil by steam distillation from the leaves and flowering tops. (An absolute is occasionally produced by solvent extraction.)

CHARACTERISTICS: A dark green or bluish oil with a spicy, warm, bitter-green odour and a sharp, fresh topnote. The ‘de-thujonized’ oil blends well with oakmoss, jasmine, neroli, lavender and hyacinth.

PRINCIPAL CONSTITUENTS: Thujone (up to 71 per cent), azulenes, terpenes.

SAFETY DATA: Toxic. Abortifacient. Habitual use can cause restlessness, nightmares, convulsions, vomiting and, in extreme cases, brain damage. In 1915 the French banned the production of the drink Absinthe with this plant, due to its narcotic and habit-forming properties.

AROMATHERAPY/HOME: USE None. ‘Should not be used in therapy either internally or externally.’.

OTHER USES: Occasionally used in rubefacient pharmaceutical preparations and as a fragrance component in toiletries, cosmetics and perfumes. Widely employed (at minute levels) as a flavouring agent in alcoholic bitters and vermouths; also to a lesser extent in soft drinks and some foods, especially confectionery and desserts.... wormwood