*cell-surface molecules that are important for binding cells to neighbouring cells (intercellular adhesion molecules, ICAM) and tissues. Absence or weakening of intercellular binding facilitates the local spread of cancer.
The abnormal union of two normally separate tissues. Adhesion may occur after in?ammation or surgery; the result is often a ?brous band between the adjacent tissues. Examples are adhesions between joint surfaces – which reduce mobility of a joint – or, after operation, between loops of intestine, where the ?brous band may cause obstruction. Movement of the heart may be restricted by adhesions between the organ and its membranous cover, the pericardial sac.... adhesion
molecules on the surface of cell membranes that are responsible for most cellular functions directly related to their immediate environment. Many have very precise functions of adhesion (see adhesion molecules), metabolic exchange, hormone reception, respiration, and immune reactions. Cell-to-cell exchanges involve specialized surface structures (junctions), which form a communicating nexus.... cell-surface molecules
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