n. the start of secretion of *androgens by the adrenal glands, occurring at around 6–7 years of age in girls and 7–8 in boys. It is usually determined by the measurement of urinary 17-ketosteroids rather than direct assay of the androgens themselves. Adrenal androgens are *dehydroepiandrosterone (DHEA), DHEA sulphate, and androstenedione. The age of adrenarche is unrelated to the age of *gonadarche. Premature adrenarche is usually manifested as the early appearance of pubic hair due to levels of the adrenal androgens equivalent to those found in puberty. It does not proceed to full puberty as the gonads do not become active.
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