Advanced glycation end-products Health Dictionary

  1. Health Encyclopedia
  2. Advanced Glycation End-products

Advanced Glycation End-products: From 1 Different Sources

damaged proteins that result from the *glycation of a large number of body proteins, which can accumulate and cause permanent damage to tissues. This damage is more prevalent in diabetics due to chronic exposure to blood with high concentrations of glucose. It is believed to be partly responsible for the damage to the kidneys, eyes, and blood vessels that characterizes long-standing diabetes.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Labelling Of Herbal Products

The law requires labels to carry a full description of all ingredients. No label should bear the name of a specific disease or promote treatment for any serious disease or condition requiring consultation with a registered medical practitioner. Labels must not contravene The Medicines (Labelling and Advertising to the Public), SI 41, Regulations, 1978.

Misleading claims and the use of such words as “organic”, “wholesome”, “natural” or “biological” cannot be accepted on product labels. The Licensing Authority treats herbal manufacturers no differently than manufacturers of allopathic products for serious conditions.

The Advertising Standards Authority does not allow quotation of any medicinal claims, except where a Product Licence (PL) has been authorised by the Licensing Authority.

All labels must include: Name of product (as on Product Licence), description of pharmaceutical form (tablet, mixture etc), Product Licence No., Batch No., quantity of each active ingredient in each unit dose in metric terms; dose and directions for use; quantity in container (in metric terms); “Keep out of reach of children” or similar warning; Name and address of Product Licence Holder; expiry date (if applicable); and any other special warnings. Also to appear: excipients, method/route of administration, special storage instructions, and precautions for disposal, if any.

Where licences are granted, the following words should appear on the label of a product: “A herbal product traditionally used for the symptomatic relief of . . .”. “If symptoms persist see your doctor.” “Not to be used in pregnancy” (where applicable). “If you think you have . . . consult a registered medical practitioner before taking this product.” “If you are already receiving medical treatment, tell your doctor that you are taking this product.” These warnings are especially necessary should symptoms persist and be the start of something more serious than a self-limiting condition.

Herbal preparations should be labelled with the additives and colourings they contain, if any. This helps practitioners avoid prescribing medicines containing them to certain patients on whom they may have an adverse reaction.

Labels of medicinal products shall comply with the Medicines (Labelling) Regulations 1976 (SI 1976 No. 1726) as amended by the Medicines (Labelling) Amendment Regulations 1977 (SI 1977 No. 996), the Medicines (Labelling) Amendment Regulations 1981 (SI 1981 No. 1791) and the Medicines (Labelling) Amendment Regulations 1985 (SI 1985 No. 1558).

Leaflets issued with proprietory medicinal products shall comply with the requirements of the Medicines (Leaflets) Regulations 1977 (SI 1977 No. 1055).

See also: ADVERTISING: CODE OF PRACTICE. BRITISH HERBAL MEDICINE ASSOCIATION. ... labelling of herbal products

Labelling Of Herbal Products By A Practitioner

Labelling regulations require every dispensed product, i.e. a container of medicine, lotion, tablets, ointment, etc, to be labelled with the following particulars:–

1. Name of the patient.

2. Name and address of the herbal practitioner.

3. Directions for use of the remedy.

4. Liquid preparations for local or topical use to be clearly marked: For external use only.

Statutory Instruments: Medicine (Labelling) Regulations 1976 No. 1726. Medicines (Labelling) Regulations 1977 No. 996. ... labelling of herbal products by a practitioner

Over-the-counter Products

Herbal products are chiefly used to relieve symptoms of self- limiting conditions. Such products are either P (pharmacy only) or GSL (General Sales List). The Medicines (Labelling and Advertising to the Public) Regulations 1978 (SI 1978 No 41) state the range of conditions on schedule 2, parts I-IV. Dried herbs on sale under their plant or botanical name over the counter are exempt, provided no medicinal claims are made. ... over-the-counter products

Blood Products

Donated blood that is separated into its various components: red cells, white cells, platelets, and plasma (see blood donation). Each blood product has a specific lifespan and use in blood transfusion. Packed red cells (blood with most of the plasma removed) are used to treat patients with some forms of chronic anaemia and babies with haemolytic disease of the newborn. Washed red cells (with white blood cells and/or plasma proteins removed) are used when a person needs repeated transfusions because there is less risk of an allergy to any of the blood components developing.

Platelets may be given in transfusions for people with blood-clotting disorders. Patients who have life-threatening infections may be treated with granulocytes, a type of white blood cell. Fresh frozen plasma is used to correct many types of bleeding disorder because it contains all the clotting factors. Albumin, prepared from the plasma of whole blood, is used mainly to treat shock resulting from severe blood loss until compatible whole blood becomes available. Purified albumin preparations are used to treat nephrotic syndrome and chronic liver disease.

Concentrates of blood clotting factors and are used in the treatment of haemophilia and Christmas disease.

Immunoglobulins (also called antibodies), which are extracted from blood plasma, can be given by injection (see immunoglobulin injection) to protect people who are unable to produce their own antibodies or have already been exposed to an infectious agent, or to provide short-term protection against hepatitis A.

Immunoglobulins are given in large doses to treat certain autoimmune disorders.... blood products

Advanced Life Support

(ALS) a structured and algorithm-driven method of life support for use in the severest of medical emergencies, especially cardiac arrest. Doctors, nurses, and paramedic personnel involved in ALS receive special training in the use of equipment (e.g. defibrillators and appropriate drugs). Paediatric advanced life support (PALS) is ALS for use in severe medical emergencies in children, while advanced trauma life support(ATLS) is specifically for patients who have been subjected to major trauma, such as a serious road accident. Compare basic life support.... advanced life support

Glycation

n. the chemical linkage of glucose to a protein, to form a glycoprotein. Glycation of body proteins has been postulated as a cause of complications of diabetes mellitus. see advanced glycation end-products; glycated haemoglobin.... glycation

Medicines And Healthcare Products Regulatory Agency

(MHRA) a UK government agency that regulates the use of medicinal drugs and medical devices. The agency regulates and issues *licences for the clinical trial, manufacture, and marketing of new products. It also applies the regulations governing the collection, storage, and use of human blood and blood products.

MHRA section of the website... medicines and healthcare products regulatory agency


Health encyclopedia icon Health Encyclopedia

Recent Searches