One of the AMINOGLYCOSIDES, amikacin is a semi-synthetic derivative of KANAMYCIN, which is used to treat infections caused by microorganisms resistant to GENTAMICIN and TOBRAMYCIN.
A group of antibiotics usually reserved for use in patients with severe infections. They are e?ective against a wide range of BACTERIA including some gram-positive and many gram-negative organisms (see GRAM’S STAIN). Aminoglycosides must be used cautiously because they can damage the inner ear – thus affecting hearing – and the kidneys. Examples of this group are AMIKACIN and GENTAMICIN (e?ective against Pseudomonas aeuriginosa), NEOMYCIN (used only for topical administration for skin infections), and STREPTOMYCIN (e?ective in combination with other drugs against Mycobacterium tuberculosis).... aminoglycosides
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