Anabolism Health Dictionary

Anabolism: From 3 Different Sources


The manufacture of complex molecules, such as fats and proteins, from simpler molecules by metabolic processes in living cells. (See also catabolism; metabolism.)
Health Source: BMA Medical Dictionary
Author: The British Medical Association
Production by the body of complex molecules like fat and proteins from simpler substances taken in the diet.
Health Source: Medical Dictionary
Author: Health Dictionary
n. the synthesis of complex molecules, such as proteins and fats, from simpler ones by living things. See also anabolic; metabolism.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Metabolism

This means tissue change, and includes all the physical and chemical processes by which the living body is maintained – as well as those by which the energy is made available for various forms of work. The constructive, chemical and physical, processes by which food materials are adapted for the use of the body are collectively known as ANABOLISM. The destructive processes by which energy is produced with the breaking-down of tissues into waste products is known as CATABOLISM. Basal metabolism is the term applied to the energy changes necessary for essential processes such as the beating of the heart, respiration, and maintenance of body warmth. This can be estimated, when a person is placed in a state of complete rest, by measuring the amounts of oxygen and carbon dioxide exchanged during breathing under certain standard conditions. (See also CALORIE.)... metabolism

Adrenal Cortex

The outer covering of the two adrenal glands that lie atop each kidney. Embryonically derived from gonad tissue, they make steroid hormones that control electrolytes, the management of fuels, the rate of anabolism, the general response to stress, and maintenance of nonspecific resistance.... adrenal cortex

Anabolic

Promoting anabolism. Specifically, an agent or function that stimulates the organization of smaller substances into larger ones. Examples: making a starch out of sugars, a protein out of amino acids, or making triglycerides out of fatty acids are anabolic functions. Anabolic steroids are internal or external substances that will induce increased body size or mass. The opposite of CATABOLIC.... anabolic

Anabolic Steroids

The nitrogen-retaining e?ect of ANDROGEN, a steroid hormone, is responsible for the larger muscle mass of the male. This is called an anabolic e?ect. Attempts have been made to separate the anabolic effects of hormones from their virilising effects (see VIRILISATION), but these have been only partially successful. Thus, anabolic steroids have the property of protein-building so that when taken, they lead to an increase in muscle bulk and strength. All the anabolic steroids have some androgenic activity but they cause less virilisation than androgens in women. Androgenic side-effects may result from any of these anabolic compounds, especially if they are given for prolonged periods: for this reason they should all be used with caution in women, and are contraindicated in men with prostatic carcinoma. Jaundice due to stasis of bile in the intrahepatic canaliculi is a hazard, and the depression of pituitary gonadotrophin production is a possible complication.

Anabolic steroids have been used to stimulate protein anabolism in debilitating illness, and to promote growth in children with pituitary dwar?sm and other disorders associated with interference of growth. Stimulation of protein anabolism may also be of value in acute renal failure, and the retention of nitrogen and calcium is of probable bene?t to patients with OSTEOPOROSIS and to patients receiving corticosteroid therapy. Anabolic steroids may stimulate bone-marrow function in hypoplastic ANAEMIA.

They have been widely abused by athletes and body-builders aiming to improve their strength, stamina, speed or body size. However, there are considerable doubts over their e?cacy, with little experimental evidence that they work. Dangerous adverse effects include precocious myocardial infarction (see HEART, DISEASES OF – Coronary thrombosis), DIABETES MELLITUS, liver disease, precocious carcinoma of the prostate, acne, and severe psychiatric disorders. Anabolic steroids should not be used by athletes, who face bans from o?cial competitions if they take them.

The anabolic steroids in therapeutic use include nandrolone and stanozolol.... anabolic steroids




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