Linn. var. himalaica (C. B. Clarke) Krishna and BadhwarFamily: Umbelliferae; Apiaceae.
Habitat: Native to Syria; now grown in Kashmir at 1,000-3,900 m.
Ayurvedic: Chandaa, Chandaam- shuka, Kathachoraa.Action: Expectorant, carminative, digestant, cholagogue, antispas- modic, diaphoretic, diuretic, anti-inflammatory, smooth muscle relaxant, antifungal, antibacterial.
Key application: In flatulence and peptic discomforts. The root is a component in numerous gastrointestinal, cholagogue and biliary remedies in Germany. (Angelica root is an approved herb, whereas the seed and above-ground parts have been included among unapproved herbs by German Commission E.)Chinese angelica root, Dong Quai, is equated with Angelica sinensis. It is prescribed internally for menstrual irregularity, lack of menstruation and painful menstruation.The roots from Kashmir yield furo- coumarins, phenol compounds and flavonoids.Xanthotoxol exhibited antihista- mintic and antinicotinic activities on guinea-pig ileum. The dry extract has been shown to have anti-inflammatory activityThe root is reported to inhibit bacterial and fungal growth.Furocoumarins, especially psoralen and 8-methoxypsoralen, are used in the photochemotherapy of psoriasis and vitiligo. The biological activity is due to covalent linkage formed with DNA by irradiation with long- wavelength UV light.Most of the coumarins have shown significant calcium antagonistic activity in vitro.Angelicin, a resin, is stimulating to the lungs and skin. contraindicated in bleeding disorders, peptic ulcers and pregnancy. (Sharon M. Herr.)Dosage: Root—1-3 g powder. (CCRAS.)
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