Anti-müllerian Hormone: From 1 Different Sources
see Müllerian duct.
A chemical produced in the body by endocrine glands and carried in the blood to other organs where the hormone causes processes to change in the target organ. A chemical messenger.... hormone
A hormone produced by the anterior PITUITARY GLAND which stimulates the formation of follicles in the ovary each menstrual cycle (see OVARIES; MENSTRUATION) and of spermatocytes in the testis (see TESTICLE). It is under hypothalamic control (see HYPOTHALAMUS) and in the female there is feedback inhibition by oestrogens from the developing follicle.... follicle-stimulating hormone
(LH) This is a sugar-bearing protein manufactured by the anterior pituitary. Like a lot of the pituitary hormones, it surges on and off, since constant secretion would overload and deaden receptors. In women, it builds up after menses, stimulating the release of estrogen from the ovaries. Estrogen in turn stimulates the hypothalamus to increase its stimulation of LH from the pituitary, until, a day or two before ovulation, they produce a guitar-amp feedback, and the cells that produce LH start to surge follicle-stimulating hormone (FSH). The egg pops, being replaced by the corpus luteum, which produces progesterone for the next eleven to twelve days. Progesterone inhibits and lowers LH levels, as well as inhibiting levels of estrogen already being produced by the young follicles that will produce next month’s egg. In men, LH is responsible for stimulation of testosterone, although FSH and the testes hormone inhibin are responsible for both the production of sperm and controlling testosterone.... luteinizing hormone
Within a few years medical scientists have introduced into the domestic scene a steroid which has changed the whole course of female history. HRT has solved some basic medical problems by making good the loss of oestrogen in a woman’s body when menstruation is finished and her body learns to adjust.
A lack of oestrogen induces hot flushes, night sweats, thinning of the bones (osteoporosis) with possible fractures, and a wide range of physical and emotional disorders.
HRT also prevents the increased frequency of coronary disease which may follow the menopause. With oestrogen only, HRT appears to increase the incidence of cancer of the uterine body. Use of oestrogen and progestogen avoids this.
HRT is available as a tablet, transdermal patch, implant or topical cream. Most women notice temporary improvement in their appearance and hot flushes as long as treatment is continued. HRT is not prescribed by the herbal practitioner. Soya and Hops are a mild alternative.
Side-effects of such treatment include blood pressure rise, weight gain and periods probably continue with a monthly bleed. Elderly women taking HRT for osteoporosis may develop bleeding problems, the risk of blood clot and gall bladder diseases.
Helonias has proved a useful alternative, effective in eliminating excess fluids, reducing hot flushes, and relieving that bloated feeling, thus helping the older woman to live a normal life.
Damiana. 1 heaped teaspoon leaves to each cup boiling water; infuse 5-10 minutes; strain. 1 cup 2-3 times daily for 3-6 weeks.
Sarsaparilla. 1oz (30g) root in 1 pint (500ml) water; simmer gently 20 minutes; strain. 1 cup 2-3 times daily for 3-6 weeks.
Supplementation. Daily. Vitamin E, 400iu. Vitamin B-complex (high potency). Evening Primrose oil capsules, 500mg morning and evening. Dolomite, for Calcium and Magnesium, 2 tablets morning and evening.
Note: An extensive study of breast cancer risks with HRT revealed a positive link between the risk of cancer and length of use. Risk of the disease increased with all types of women using HRT with every year of use. Pre-menstrual women were more than twice at risk. It would appear that oestrogens cannot be taken without risk. (Centre for Disease Control, Atlanta, USA) See: OESTROGENS. ... hormone replacement therapy (hrt)
These are ‘chemical messengers’ that are dispersed by the blood and act on target organs to produce effects distant from their point of release. The main organs involved in hormone production are the PITUITARY GLAND, PANCREAS, ovary (see OVARIES), testis (see TESTICLE), THYROID GLAND, and ADRENAL GLANDS. The release of many hormones is, ultimately, under the control of the central nervous system via a series of inhibiting and releasing factors from the HYPOTHALAMUS. Hormones are involved in maintaining homeostasis: for example, insulin regulates the concentration of glucose in the blood. They also participate in growth and maturation: for example, growth hormone promotes growth and helps to regulate fat, carbohydrate, and protein metabolism; and the sex hormones promote sexual maturation and reproduction. (See also ENDOCRINE GLANDS.)... hormones
These HORMONES control the development of primary and secondary sexual characteristics. They also regulate sex-related functions – for example, menstruation and the production of sperm and eggs. The three main types of sex hormone are androgens, or male sex hormones (see ANDROGEN); OESTROGENS, or female sex hormones; and progesterones, which are involved in pregnancy (see PROGESTERONE).... sex hormones
(LH-RH) The same substance as Follicle-Stimulating-Hormone Releasing Hormone (FSH-RH), both of which are actually Gonadotrophin-Releasing Hormone (GnRH or GRH). Confused? Imagine being an endocrinologist 20 years ago. These (This) are (is) a peptide secreted into the little portal system that drains from the hypothalamus to the pituitary. If it is surged hourly and not too strongly, the pituitary secretes LH and the ovaries secrete estrogen. If it is surged hourly and strongly, the estrogens rise drastically, the pituitary secretes FSH, you pop an egg, start the corpus luteum and begin progesterone secretion. The surge is now slowed to every four or five hours, not too strongly, and the pituitary secretes LH every four or five hours...and the ovaries make progesterone. The same hypothalamic hormone triggers different pituitary responses based on AMPLITUDE and FREQUENCY.... luteinizing-hormone releasing hormone
See ACTH.... adrenocorticotrophic hormone
See ADH.... antidiuretic hormone
1. adj. describing a drug that reduces *inflammation. The various groups of anti-inflammatory drugs act against one or more of the mediators that initiate or maintain inflammation. Some groups suppress only certain aspects of the inflammatory response. The main groups of anti-inflammatory drugs are the *antihistamines, the glucocorticoids (see corticosteroid), and the nonsteroidal anti-inflammatory drugs (see NSAID). 2. n. an anti-inflammatory drug.... anti-inflammatory
ACTH is the commonly used abbreviation for CORTICOTROPIN.... acth (adrenocorticotrophic hormone)
See also CORTICOTROPIN. A hormone which is released into the body during stress. Made and stored in the anterior PITUITARY GLAND, ACTH regulates the production of corticosteroid hormones from the ADRENAL GLANDS, and is vital for the growth and maintenance of the adrenal cortical cells. Its production is in part controlled by the amount of HYDROCORTISONE in the blood and also by the HYPOTHALAMUS. ACTH participates in the FEEDBACK MECHANISM of hormone production and actions involving particularly the hypothalamus and pituitary gland. The hormone is used to test adrenal function and treat conditions such as ASTHMA. (See also CUSHING’S SYNDROME.)... adrenocorticotrophic hormone (acth)
Pre?x meaning against.... anti
See ANALGESICS; NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS).... anti-inflammatory drugs
See VASOPRESSIN.... antidiuretic hormone (adh)
See OESTRADIOL.... follicular hormone
See under MENOPAUSE.... hormone replacement therapy(hrt)
A hormone secreted by the anterior PITUITARY GLAND which stimulates OVULATION, maturation of the CORPUS LUTEUM, and the synthesis of progesterone by the ovary (see OVARIES) and testosterone by the testis (see TESTICLE).... luteinising hormone
A natural hormone released by the HYPOTHALAMUS gland in the BRAIN. It stimulates the release of GONADOTROPHINS from the PITUITARY GLAND; these control the production of the sex hormones (see ANDROGEN; OESTROGENS).... luteinising hormone-releasing hormone (lhrh)
A hormone (see HORMONES) produced and released by the HYPOTHALAMUS which stimulates the release of THYROTROPHINSTIMULATING HORMONE (TSH) by the PITUITARY GLAND.... thyrotrophin-releasing hormone (trh)
A hormone (see HORMONES) manufactured and released by the anterior part of the PITUITARY GLAND which stimulates the THYROID GLAND to manufacture and release thyroid hormones (THYROXINE and TRI-IODOTHYRONINE).... thyrotrophin-stimulating hormone (tsh)
Herbs that check any tendency to miscarriage. They should be prescribed by a practitioner and may include: Raspberry leaves, Cramp bark, Lobelia, etc. See: ABORTION. ... anti-abortives
Herbs that relieve the symptoms of asthma. According to the case the remedy may be an expectorant, antispasmodic, bronchodilator or a combination of each. A large group including:– Belladonna, Black Haw bark, Comfrey, Ephedra, Elecampane, Euphorbia, Evening Primrose, Gelsemium, Irish Moss, Lobelia, Mullein, Senega, Storax, Stramonium, Wild Cherry bark and Wild Yam are all of practitioner use. ... anti-asthmatics
These act by inhibiting the formation of PROSTAGLANDINS which are mediators of INFLAMMATION. They act both as ANALGESICS to relieve pain, and as inhibitors of in?ammation. Aspirin is a classic example of such a compound. Newer compounds have been synthesised with the aim of producing fewer and less severe side-effects. They are sometimes preferred to aspirin for the treatment of conditions such as RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, sprains, strains and sports injuries. Their main side-effects are gastrointestinal: gastric ulcers and gastric haemorrhage may result (see STOMACH, DISEASES OF). This is because prostaglandins are necessary for the production of the mucous protective coat in the stomach and, when the production of prostaglandin is inhibited, the protection of the stomach is compromised. NSAIDs should therefore be used with caution in patients with DYSPEPSIA and gastric ulceration. The various nonsteroidal anti-in?ammatory drugs di?er little from each other in e?cacy, although there is considerable variation in patient response. Ibuprofen is one of the ?rst choices in this group of drugs as it combines good e?cacy with a low incidence of side-effects and administration is only required twice daily. Other drugs in this series include diclofenac, fenbufen, fenclofenac, fenoprofen, feprazone, ?urbiprofen, indomethacin, indoprofen, ketoprofen, ketorolac, naproxen, piroxicam, sulindac, tiaprofenic acid and tolmetin.... non-steroidal anti-inflammatory drugs (nsaids)
These are fats similar to, and usually synthesized from, cholesterol, starting with Acetyl-CoA, moving through squalene, past lanosterol, into cholesterol, and, in the gonads and adrenal cortex, back to a number of steroid hormones. Nearly all of the classic hormones are proteins or smaller peptides; they don’t get inside a cell (the membrane keeps them out); instead, they bind to, and initiate, cell changes from the outside. The exceptions are the thyroxines (from the thyroid) and the steroid hormones. They move into the cell, bind with receptors, and initiate changes in the way a cell regenerates itself or synthesizes new compounds. Because the steroid hormones stimulate cell growth, either by changing the internal structure or increasing the rate of proliferation, they are often called anabolic steroids. Estrogen, an ovarian steroid, when secreted into the bloodstream, will be bound within a short time by internal receptors inside those cells that need estrogen for their growth; the unused portion is partially broken down, mostly in the liver, and partially stored in a less active form by adipose tissue. Since luteinizing hormone from the pituitary is surged in pulses an hour apart, the estrogen is also surged from the reacting ovaries, and by the time more estrogen is available, the binding cells need more; their program of synthesis has run out and needs to be started again. Of course, most steroid hormone reactions are less measured than this, but you get the idea.... steroid hormone
Remedies that inhibit release of acetylcholine as a neuro-transmitter. Given for anti-depressant therapy. May have side-effects of dry mouth, drowsiness, blurred vision. Administered by a qualified practitioner. Two chief remedies: Belladonna (atropa) and Henbane (hyoscyamus). They reduce acid secretion but are sometimes given with Comfrey and other tissue builders to promote healing. Anti-cholinergics decrease secretion of gastric juices by their control of the vagus nerve. ... anti-cholingergics
Usually refers to children with fevers. Herbs for a febrile seizure, or for prevention and reduction of epileptic fits. Usually given orally, but where this is not possible a rectal injection or a suppository (such as Valerian) may be used. Another term for ‘antispasmodics’. ... anti-convulsants
Agents that reduce the production of mucus. Angelica, Avens, Bayberry, Bistort, Blood root, Cayenne, Chamomile (German), Coltsfoot, Comfrey, Elderflowers, Elecampane, Eyebright, Fenugreek, Garlic, Ginger, Goldenseal, Gotu Kola, Ground Ivy, Hyssop, Iceland Moss, Irish Moss, Juniper, Liquorice, Marsh Cudweed, Marshmallow, Mountain Grape, Mouse Ear, Mullein, Myrrh, Parsley, Plantain, Poke root, Senega, Skunk Cabbage, White Horehound, Wild Cherry bark, Wild Indigo, Witch Hazel, Yarrow. Successful treatment of catarrh is often dependent upon efficient kidney, skin and bowel function which may require also, diuretics, alteratives and laxatives. ... anti-catarrhals
Herbs with an ability to arrest diarrhoea or soothe an irritable bowel. According to degree, an astringent may have a similar effect. A large group including:– Avens, Bistort, Catnep, Cinnamon, Hemlock Spruce, Holy Thistle, Kola nuts, Matico, Orris root, Rhatany root. ... anti-diarrhoeals
See: CARMINATIVES. ... anti-flatulents
A group of powerful astringents clinical experience has shown to be effective in arresting mild to moderate internal bleeding.
Digestive tract: Marigold, Comfrey, Bur-Marigold, Matico, Shepherd’s Purse, Holy Thistle, American Cranesbill, Goldenseal.
Anal/Rectal: Pilewort, Plantain, Matico, Rhatany root, Witch Hazel.
Mouth: Tormentil.
Nose-bleeds: Nettles.
Uterus. Shepherd’s Purse, Ladies Mantle, Greater Periwinkle, Beth root, Avens, Goldenseal. Urinary system. Bistort, Plantain, Marigold, Stone root, Horsetail, Bur-Marigold.
Lungs. Bugleweed, Elecampane, Lungwort.
Colon. Greater Burnet, Matico, Comfrey, Bistort, Wild Yam, Holy Thistle, Avens, Tormentil. Capillary haemorrhage. Buckwheat. ... anti-haemorrhagics
Herbs that stimulate the body’s immune system to withstand infection. Alternatives to anti-bacterial substances obtained from micro-organisms as penicillin, streptomycin etc. Those from herbs do not destroy beneficial bacteria normally present in the intestines, neither does the body get used to them.
Some essential oils are natural antibiotics. Others: Blue Flag root, Buchu, Chaparral, Butterbur, Echinacea, Feverfew, Garlic, Goldenseal, Holy Thistle, Horse Radish (Vogel), Juniper berries, Myrrh, Nasturtium, Poke root, Red Clover, Watercress (Vogel), Wild Indigo, Wild Thyme.
Vitamin C is a powerful antibiotic (1-2g daily).
ANTI-INFLAMMATORIES. A group of agents known to reduce inflammation. Action is not to suppress but to enable tissue to return to normal on the strength of its own resources. Some members of the group are helpful for chronic conditions such as polyarthritis and rheumatism caused by a sub-acute inflammation going on quietly over a long time. Others work by blocking prostaglandin synthesis. General. Chamomile (German, Roman), Cowslip root, Fennel, Feverfew, Heartsease, Mistletoe, Turmeric, Yellow Dock.
Specific. Bistort (bowel). Comfrey (bones). Devil’s Claw (muscles). St John’s Wort (nerve tissue). Lignum vitae (rheumatic joints). Poke root (lymph vessels). Eyebright (conjunctivitis: topical as an eye lotion). Horsechestnut (anus). Bogbean (liver and gall bladder).
Steroid-like action. Ginseng, Black Cohosh, Black Haw, Liquorice, Wild Yam.
Aspirin-like action. Birch, Black Willow bark, Meadowsweet, White Poplar bark, White Willow bark, Wintergreen.
Some types of inflammation may be reduced by herbs that stimulate the eliminatory organs – lungs, bowel, skin and kidneys. A timely enema may reduce a high temperature with inflammation, to expel toxins and unload an over-loaded bowel; (Dandelion root, Parsley root, Sarsaparilla).
ANTI-INFLAMMATION FORMULA. (Biostrath). Drops containing cultures combined with extracts derived from medicinal plants possessing known therapeutic properties: Arnica, Bryony, Balm, Chamomile, Horseradish, Marigold, Hypericum, Echinacea.
Indications: colic, inflammation of the alimentary tract. ... anti-infectives
Remedies that arrest fungal growth on the skin or mucous membrane. See: ANTI- FUNGAL. ... anti-mycotics
Herbs that arrest or inhibit vomiting and nausea. Black Horehound. ... anti-nauseants
Herbs that prevent formation or destroy tumour cells. Some reported in the literature to arrest the spread of malignancy. A neoplasm is a new growth and may be malignant or non- malignant. Bayberry (intestinal), Bryonia (lung), Clivers (Genito-urinary tract), Comfrey (general), Condurango (gastric), Dandelion (liver), Echinacea, Greater Celandine (epithelial), Mandrake (face and skin), Mistletoe, Myrrh, Plantain (throat), Poke root (breast), Queen’s Delight, Red Clover (epithelial and breast), Rosebay Willowherb (gastric), Vinca rosea (leukaemia), Thuja (womb), Wild Violet (breast and womb), Yellow Dock. ... anti-neoplastics
Plant medicines that destroy or inhibit growth of disease-causing bacteria or other micro-organisms. Aniseed, Barberry, Bayberry, Bearberry, Benzoin, Blood root, Buchu, Camphor, Caraway oil, Catechu, Cayenne, Cinnamon, Clove, Cornsilk, Coriander, Echinacea, Elecampane, Eucalyptus, Fennel seed, Garlic, Gentian, Goldenseal, Guaiacum, Heather flowers (Calluna), Hemlock Spruce bark, Juniper, Kava Kava, Kino, Labrador tea, Lavender, Liquorice, Lovage root, Mandrake, Marigold, Marjoram, Meadowsweet, Mountain Grape, Myrrh, Nasturtium, Olive, Orthosiphon, Parsley root, Peppermint, Peruvian balsam, Plantain, Propolis, Rosemary, Rue, Sage, St John’s Wort, Southernwood, Thuja, Thyme, Turmeric, White Pond Lily, Wild Indigo, Wood Sage, Wormwood, Yarrow. ... anti-microbials
Remedies that inhibit the action of protozoa, a class of single-celled microscopic animals. Ipecacuanha, Peruvian bark. ... anti-protozoals
Agents to relieve intense itching. Chamomile, Chickweed, Clivers, Cucumber, Goldenseal, Marigold, Sarsaparilla, Peppermint, St John’s Wort. ... anti-pruritics
Another term for FEBRIFUGE. ... anti-pyretic
Herbs that may relieve discomforts of rheumatism and arthritis. Bearberry, Black Cohosh, Blue Cohosh, Black Willow, Bladderwrack, Blue Flag root, Bogbean, Boneset, Burdock, Calluna (Heather flowers), Cayenne, Celery seed, Chickweed, Couchgrass, Cowslip (Biostrath), Dandelion, Devil’s Claw, Guaiacum, Juniper, Lavender, Meadowsweet, Mountain Grape, Nettles, Parsley root, Poke root, Prickly Ash, Sarsaparilla, Pipsissewa, White Poplar, Wild Yam, Wintergreen, Wood Sage, Willow (Biostrath), Wormwood, Yarrow, Yellow Dock. ... anti-rheumatics
Agents that relieve or cure scurvy. Bogbean, Burdock, Chickweed, Clivers, Cubebs, Blue Flag root, Lemon juice, Sorrel, Nettles, Sarsaparilla, Yellow Parilla, Yellow Dock, Watercress. ... anti-scorbutics
An agent that tends to reduce glandular inflammation and swelling, and inhibits onset of tuberculosis of the lymphatics. See: LYMPHATICS. ... anti-scrofulous
Agents for relief of muscular cramp, spasm or mild pain. To reduce spasm of smooth muscle. The key remedy is Cramp bark but all have their specific uses.
They may be general (Black Haw, Cramp bark), or those that exert their influence upon specific structures: Hyssop (lungs), Cloves (mucous membranes), Wild Thyme (bronchi), Figwort (anus).
Others in common use: Asafoetida, Balm, Betony, Black Haw (muscles generally, also womb), Black Cohosh, Blue Cohosh, Butterburr, Blood root (externally), Cayenne, German Chamomile (stomach), Dong Quai (ovaries), Eucalyptus, Hops (stomach), Ladyslipper, Liquorice, Lime Blossom, Lobelia, Mistletoe, Motherwort (heart), Nutmeg (angina), Passion Flower, Skullcap, Skunk Cabbage, Thyme, Valerian, Vervain, Wild Cherry (respiratory), Wild Carrot (kidneys and bladder), Wild Lettuce, Wild Yam. Devil’s Claw (muscles).
Anti-Spasmodic Drops (Heath and Heather). Cramp, neuralgia, etc. Tincture Myrrh 6 per cent; Tincture Capsic 15 per cent; with 45 per cent ethanol extractive from Scutellaria (Skullcap) 10 per cent; Lobelia 1.25 per cent; Fennel 2.5 per cent; American Valerian 5 per cent. Dose: 10-30 drops according to age.
John Christopher: 2oz crushed Lobelia seeds; half an ounce Lobelia herb; 1 teaspoon Cayenne; macerated in 1 pint cider 8 days. 1-2 teaspoon when necessary.
Combination: powders. Equal parts: Skullcap, Valerian, Lobelia, Black Cohosh. Myrrh quarter part. Mix. Sift. Quarter of a teaspoon in water, honey etc as necessary.
Formula. Powders. Cramp Bark 2; Skullcap 1; Cloves half; Cayenne Pepper quarter. Mix. Dose: 500mg (two 00 capsules or one-third teaspoon thrice daily. (Indian Herbology of North America, Alma R. Hutchens) ... anti-spasmodics
See: ANTI-NEOPLASTICS. ... anti-tumours
To reduce cough severity, ease expectoration and clear the lungs. Over a hundred medicinal plants are listed from which the following are a small selection: Angelica, Balm of Gilead, Coltsfoot, Comfrey, Cowslip, Elecampane, Fenugreek, Garlic, Grindelia Hyssop, Linseed, Liquorice, Marshmallow, Irish Moss, Mousear, Mullein, Pleurisy root, Senega, Sweet Chestnut leaves, Sundew, Violet leaves, Thyme (Garden or Wild), White Horehound, Slippery Elm bark, Marsh Cudweed,. ... anti-tussives
Agents that have anti-bacterial action on most strains of staphylococcus. For treatment of pus-forming lesions, necrotic tissue and for after-surgery infections.
Angostura, Balm, Barberry, Bayberry, Bearberry, Benzoin, Bistort, Blood root, Black Cohosh, Black Currant, Buchu, Bugleweed (Lycopus virginicus and Lycopus europaeus), Butternut (Juglans cinerea), Camphor, Catechu, Cola, Cornsilk, Elecampane, Eucalyptus, Fringe Tree, Goldenseal, Guaiacum, Holy Thistle, Hops, Jaborandi, Jalap, Jambul, Juniper, Kino, Ladysmantle, Labrador tea, Lavender, Liquorice, Male fern, Mandrake, Marjoram, Meadowsweet, Mountain Grape, Myrtle (common), Oleander, Olive, Orthosiphon, Pennyroyal, Peony (common), Pine (Hemlock spruce), Pulsatilla, Rhus toxicodendron, Sage, St John’s Wort, Senna, Sumach, Sumbul, Sundew, Thuja, Turmeric, Unicorn root true, Walnut (juglans regia), Wild Indigo. Propolis, a resin foraged by bees for the exclusion of draughts in the hive has proved to be an effective anti-staphylococcal. ... anti-staphylococcals
Drugs that reduce inflammation. The main groups of these drugs are nonsteroidal antiinflammatory drugs and corticosteroid drugs. (See also analgesic drugs.)... anti-inflammatory drugs
A group of hormones produced by the adrenal glands that control the body’s use of nutrients and the excretion of salts and water in the urine.... corticosteroid hormones
A group of hormones released from specialized cells in the stomach, pancreas, and intestine that control various functions of the digestive organs. Gastrin, secretin, and cholecystokinin are the best known of these hormones.... gastrointestinal hormones
Hormones that stimulate cell activity in the ovaries and testes. Gonadotrophins are essential for fertility. The two most important gonadotrophins are follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are secreted by the pituitary gland. Another gonadotrophin, HCG (see gonadotrophin, human chorionic), is produced by the placenta during pregnancy. Certain gonadotrophins are used as drugs in the treatment of infertility.... gonadotrophin hormones
A drug that blocks the action of a hormone.... hormone antagonist
n. any one of a group of drugs that inhibit the action of testosterone on the prostate gland by blocking androgen receptors, competing for binding sites, or decreasing androgen production. They are therefore used in the treatment of prostate cancer, which is an androgen-dependent tumour. Anti-androgens include *abiraterone acetate, *bicalutamide, *cyproterone, *finasteride, and *flutamide.... anti-androgen
adj. describing a group of drugs used to correct irregularities in the heartbeat (see arrhythmia). They include *adenosine, *amiodarone, *verapamil, *disopyramide, *flecainide, and *lidocaine.... anti-arrhythmic
(anti-D Ig) a preparation of anti-D, a *rhesus factor antibody formed by Rh-negative individuals following exposure to Rh-positive blood (usually by exchange between fetal and maternal blood in Rh-negative women who carry a Rh-positive fetus). Anti-D Ig is administered (by intramuscular injection) to Rh-negative women within 72 hours of giving birth to a Rh-positive child (or following miscarriage or abortion) to prevent the risk of *haemolytic disease of the newborn in a subsequent child. It rapidly destroys any remaining Rh-positive cells, which could otherwise stimulate antibody production affecting the next pregnancy. Anti-D is also available as antenatal prophylaxis to all Rh-negative pregnant women.... anti-d immunoglobulin
(oestrogen-receptor antagonist) n. one of a group of drugs that oppose the action of oestrogen by binding to *oestrogen receptors in the body’s tissues. The most important of these drugs is currently *tamoxifen, which is used in the treatment of breast cancers dependent on oestrogen. Because they stimulate the production of pituitary *gonadotrophins, some anti-oestrogens (e.g. *clomifene, tamoxifen) are used to induce or stimulate ovulation in infertility treatment. Side-effects of anti-oestrogens include hot flushes, itching of the vulva, nausea, vomiting, fluid retention, and sometimes vaginal bleeding.... anti-oestrogen
see cytokine inhibitor.... anti-tnf drugs
an agent that inhibits the action of *vascular endothelial growth factor (VEGF). See angiogenesis inhibitor.... anti-vegf
(CRH) a peptide hypothalamic hormone (of 41 amino acids) stimulating the release of *ACTH (adrenocorticotrophic hormone) from the anterior pituitary. Its own release is suppressed by a *negative feedback loop involving cortisol, and its action is increased by antidiuretic hormone (see vasopressin) and *angiotensin II. It can be administered intravenously as part of the CRH test, during which blood is analysed at 15-minute intervals for one hour for the ACTH response, which is excessive in cases of primary adrenal failure and suppressed in cases of anterior *hypopituitarism.... corticotrophin-releasing hormone
a hormone produced by cells that do not usually produce it. Some tumour cells secrete hormones; for example, small-cell lung cancer cells secrete antidiuretic hormone and cause *hyponatraemia.... ectopic hormone
(GnRH, gonadorelin) a peptide hormone produced in the hypothalamus and transported via the bloodstream to the pituitary gland, where it controls the synthesis and release of pituitary *gonadotrophins. It may be used to test the ability of the pituitary to produce gonadotrophins. *Gonadorelin analogues are used to treat endometriosis, fibroids, some types of infertility, and prostate cancer.... gonadotrophin-releasing hormone
a family of plasma proteins whose function is to bind free hormone molecules to varying degrees and thus reduce their function. Alterations in levels of the binding globulins, for example during pregnancy or ill health, can result in variations in assays of hormone levels in individuals. Examples include thyroid-binding globulin, sex-hormone-binding globulin, and corticosteroid-binding globulin.... hormone-binding globulins
see luteinizing hormone.... interstitial-cell-stimulating hormone
see prolactin.... lactogenic hormone
(luteotrophin) see prolactin.... luteotrophic hormone
(MSH) a peptide hormone produced and secreted by the anterior pituitary gland. In humans it stimulates production and dispersal of melanin in the melanocytes. Alpha-melanocyte-stimulating hormone (?-MSH), which is released by neurons in the hypothalamus, suppresses appetite and regulates energy balance. It also stimulates sexual activity and is involved in regulation of heart rate and blood pressure.... melanocyte-stimulating hormone
(paramesonephric duct) either of the paired ducts that form adjacent to the Wolffian ducts (see mesonephros) in the embryo. In the female these ducts develop into the Fallopian tubes, uterus, and part of the vagina. In the male anti-Müllerian hormone (AMH), produced by the fetal testis, arrests their development and by the tenth week of fetal life they have degenerated almost completely. In females AMH is produced by the ovary and levels are used as a measure of certain aspects of ovarian function, such as response to in vitro fertilization and assessing such conditions as polycystic ovary syndrome, premature ovarian failure, and intersex conditions in infants. [J. P. Müller (1801–58), German physiologist]... müllerian duct
see NSAID.... nonsteroidal anti-inflammatory drug
(PTH-RP) a protein that is secreted by certain malignant tumours and is the main cause of malignant *hypercalcaemia. PTH-RP, which has effects similar to *parathyroid hormone, stimulates generalized bone resorption and excessive calcium reabsorption in the kidney tubules. It is most commonly produced by lung tumours, squamous-cell carcinomas of other organs, melanomas, and tumours of the breast, liver, pancreas, bladder, and prostate.... parathyroid hormone-related protein
any steroid hormone, produced mainly by the ovaries or testes, that is responsible for controlling sexual development and reproductive function. *Oestrogens and *progesterone are the female sex hormones; *androgens are the male sex hormones.... sex hormone
(SIADH) a condition of inappropriately high plasma levels of ADH (see vasopressin) with associated water retention, dilutional *hyponatraemia, and the production of highly concentrated urine. Renal, adrenal, thyroid, and hepatic function are normal, as is the volume of circulating blood (euvolaemia). It is caused by a variety of pathological conditions, usually intrathoracic and intracerebral, and also by a number of drugs, including antidepressants, chemotherapy agents, and some of the older antidiabetic agents. The treatment involves fluid restriction, treatment (or removal) of the underlying cause (or drug), and, in severe cases, administration of *demeclocycline to reduce the effects of ADH on the kidney. Very rarely, hypertonic saline is given.... syndrome of inappropriate secretion of antidiuretic hormone
an iodine-containing substance, synthesized and secreted by the thyroid gland, that is essential for normal metabolic processes and mental and physical development. There are two thyroid hormones, *triiodothyronine and *thyroxine, which are formed from *thyroglobulin. Lack of these hormones gives rise to *cretinism in infants and *myxoedema in adults. Excessive production of thyroid hormones gives rise to *thyrotoxicosis.... thyroid hormone
(TSH, thyrotrophin) a hormone, synthesized and secreted by the anterior pituitary gland under the control of *thyrotrophin-releasing hormone, that stimulates activity of the thyroid gland. Raised levels of TSH are found in primary *hypothyroidism. Normal or low TSH levels in the presence of a low serum thyroxine are found in secondary hypothyroidism and the *euthyroid sick syndrome.... thyroid-stimulating hormone
(TRH) a hormone from the hypothalamus (in the brain) that acts on the anterior pituitary gland to stimulate the release of *thyroid-stimulating hormone. A preparation of TRH (protirelin) may be given by intravenous injection to test thyroid gland function and to estimate reserves of thyroid-stimulating hormone in the pituitary.... thyrotrophin-releasing hormone
an agent which combats anaemia. Anti-arthritic: an agent which combats arthritis. Antibilious: an agent which helps remove excess bile from the body.... anti-anaemic
an agent which reduces the incidence and severity of nausea or vomiting.... anti-emetic