Antivenom Health Dictionary

Antivenom: From 3 Different Sources


A specific treatment for bites or stings inflicted by venomous animals such as snakes, spiders, and scorpions.

Antivenoms are given by intravenous injection and may cause allergic reactions.

Health Source: BMA Medical Dictionary
Author: The British Medical Association
A therapeutic substance used to counteract the toxic action(s) of a speci?c animal toxin (see TOXINS) or venom. They are normally sterilised, proteinaceous globulins (see GLOBULIN) extracted from the SERUM of animals, usually horses, immunised against the speci?c toxin/ venom. Most are given by intravenous or intramuscular injection and are most e?ective when given shortly after the bite or sting has occurred. Some antivenoms may be e?ective against the venoms of several closely related animal species.
Health Source: Dictionary of Tropical Medicine
Author: Health Dictionary
Antibody mixtures produced by an animal after exposure to small doses of an injected venom that may be harmful to man. As the doses are small, the injection is not lethal and antibodies are formed. This resultant antibodymixture is then collected from the animal’s blood, purified, concentrated, and thus becomes an antivenom. It can then be injected into humans to counteract symptoms (or death) produced by the venom of the animal potentially lethal to humans. An antivenom is specific for the venom against which it is prepared, and does not neutralise other antivenoms. A rare exception to this is Tiger snake (Notechis scutatus) antivenom which can be used to effectivelycounteract the venom of the sea snakes if specific sea snake antivenom is not available.
Health Source: Medical Dictionary
Author: Health Dictionary

Bites And Stings

Animal bites are best treated as puncture wounds and simply washed and dressed. In some cases ANTIBIOTICS may be given to minimise the risk of infection, together with TETANUS toxoid if appropriate. Should RABIES be a possibility, then further treatment must be considered. Bites and stings of venomous reptiles, amphibians, scorpions, snakes, spiders, insects and ?sh may result in clinical effects characteristic of that particular poisoning. In some cases speci?c ANTIVENOM may be administered to reduce morbidity and mortality.

Many snakes are non-venomous (e.g. pythons, garter snakes, king snakes, boa constrictors) but may still in?ict painful bites and cause local swelling. Most venomous snakes belong to the viper and cobra families and are common in Asia, Africa, Australia and South America. Victims of bites may experience various effects including swelling, PARALYSIS of the bitten area, blood-clotting defects, PALPITATION, respiratory di?culty, CONVULSIONS and other neurotoxic and cardiac effects. Victims should be treated as for SHOCK – that is, kept at rest, kept warm, and given oxygen if required but nothing by mouth. The bite site should be immobilised but a TOURNIQUET must not be used. All victims require prompt transfer to a medical facility. When appropriate and available, antivenoms should be administered as soon as possible.

Similar management is appropriate for bites and stings by spiders, scorpions, sea-snakes, venomous ?sh and other marine animals and insects.

Bites and stings in the UK The adder (Vipera berus) is the only venomous snake native to Britain; it is a timid animal that bites only when provoked. Fatal cases are rare, with only 14 deaths recorded in the UK since 1876, the last of these in 1975. Adder bites may result in marked swelling, weakness, collapse, shock, and in severe cases HYPOTENSION, non-speci?c changes in the electrocardiogram and peripheral leucocytosis. Victims of adder bites should be transferred to hospital even if asymptomatic, with the affected limb being immobilised and the bite site left alone. Local incisions, suction, tourniquets, ice packs or permanganate must not be used. Hospital management may include use of a speci?c antivenom, Zagreb®.

The weever ?sh is found in the coastal waters of the British Isles, Europe, the eastern Atlantic, and the Mediterranean Sea. It possesses venomous spines in its dorsal ?n. Stings and envenomation commonly occur when an individual treads on the ?sh. The victim may experience a localised but increasing pain over two hours. As the venom is heat-labile, immersion of the affected area in water at approximately 40 °C or as hot as can be tolerated for 30 minutes should ease the pain. Cold applications will worsen the discomfort. Simple ANALGESICS and ANTIHISTAMINE DRUGS may be given.

Bees, wasps and hornets are insects of the order Hymenoptera and the females possess stinging apparatus at the end of the abdomen. Stings may cause local pain and swelling but rarely cause severe toxicity. Anaphylactic (see ANAPHYLAXIS) reactions can occur in sensitive individuals; these may be fatal. Deaths caused by upper-airway blockage as a result of stings in the mouth or neck regions are reported. In victims of stings, the stinger should be removed as quickly as possible by ?icking, scraping or pulling. The site should be cleaned. Antihistamines and cold applications may bring relief. For anaphylactic reactions ADRENALINE, by intramuscular injection, may be required.... bites and stings

Serum Sickness

A complex systemic reaction that may become evident any time up to 14 days after antivenom or antitoxin use. Symptoms are fever, generalised lymphadenopathy and an urticarial rash. Severe cases of serum sickness may have to be treated with oral steroids. The incidence of serum sickness is often related to the amount of antivenom used.... serum sickness

Jellyfish Stings

Stings from jellyfish, which belong to a group of marine animals called coelenterates or cnidarians.

Stinging capsules discharge when jellyfish tentacles are touched.

Usually, the sting causes only a mildly painful or itchy rash, but some jellyfish and Portuguese men-of-war (other members of the same group) can cause a severe sting.

Rarely, venom may cause vomiting, sweating, breathing difficulties, and collapse.

Dangerous species live mainly in tropical waters.

Antivenoms may be available.... jellyfish stings

Scorpion Stings

Injection of venom by a scorpion into a victim using a sting in its tail.

Many species are not dangerous, but some in North Africa, southern , South America, the Caribbean, and India are highly venomous.

Some stings may cause only mild pain and tingling; but in more venomous species severe pain, restlessness, sweating, diarrhoea, and vomiting can occur.

Stings are rarely fatal in adults but require prompt attention.

If pain is the only symptom, analgesics and a cold compress may be enough.

In severe cases, antivenom may be needed.... scorpion stings

Spider Bites

Nearly all spiders produce venom, which they use to kill their prey.

However, only a few species, such as the black widow in North America, are harmful to humans.

Antivenoms are available for many dangerous spider bites.... spider bites

Venomous Bites And Stings

The injection of venom by certain animals via their mouthparts (bites) or other injecting apparatus (stings). Venoms are often carried to discourage predators, and are sometimes used to kill or immobilize prey. It is rare for a venomous animal to attack a person unless it has been provoked or disturbed. Specific antivenoms are available to treat many, though not all, types of animal venom. (See also insect stings; jellyfish stings; scorpion stings; snake bites; spider bites.)... venomous bites and stings

Snake Bites

Most snake bites are by nonvenomous species. Venomous snakes are found mainly in the tropics; the only species native to the is the adder.

The effects of a venomous bite depend on the species and size of the snake, the amount of venom injected, and the age and health of the victim. A bite from an adder or other viper typically causes immediate pain and swelling at the site, followed by dizziness and nausea, a drop in blood pressure, an increase in heart-rate, and internal bleeding.

Antibiotic drugs and tetanus antitoxin injections are given for all bites to prevent infection and tetanus.

An injection of antivenom is also given for a venomous bite.

With prompt treatment, most victims recover completely.... snake bites




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