Apnoea index Health Dictionary

Apnoea Index: From 1 Different Sources


Apnoea

A general term meaning the cessation of breathing. Apnoea is a medical emergency: death soon follows if breathing is not quickly restored (see APPENDIX 1: BASIC FIRST AID). Apnoea may be caused by an obstruction to the airway, for example by the tongue during general ANAESTHESIA, or by a disturbance of the mechanisms that control breathing. Rapid heavy breathing reduces the blood levels of carbon dioxide and can lead to a brief period of apnoea.

Neonatal apnoeic attacks may represent a serious emergency, being caused by prematurity, milk aspiration, heart failure, infection, HYPOXIA, HYPOGLYCAEMIA or HYPOCALCAEMIA. If stimulation of the baby does not immediately restore breathing, then bag-and-mask ventilation should be used.... apnoea

Body Mass Index

Body Mass Index (BMI) provides objective criteria of size to enable an estimation to be made of an individual’s level or risk of morbidity and mortality. The BMI, which is derived from the extensive data held by life-insurance companies, is calculated by dividing a person’s weight by the square of his or her height (kilograms/ metres2). Acceptable BMIs range from 20 to 25 and any ?gure above 30 characterises obesity. The Index may be used (with some modi?cation) to assess children and adolescents. (See OBESITY.)... body mass index

Therapeutic Index

In anticancer therapy, this is the ratio of a dose of the treatment agent that damages normal cells to the dose necessary to produce a determined level of anticancer activity. The index shows the e?ectiveness of the treatment against the cancer.... therapeutic index

Sleep Apnoea

A disorder in which there are episodes of temporary cessation of breathing (lasting 10 seconds or longer) during sleep.

People with sleep apnoea may not be aware of any problem during the night, but they may be sleepy during the day, with poor memory and concentration. Severe sleep apnoea is potentially serious and may lead to hypertension, heart failure, myocardial infarction, or stroke.

Obstructive sleep apnoea is the most common type and may affect anyone, but more often middle-aged men, especially those who are overweight. The most common cause is over-relaxation of the muscles of the soft palate in the pharynx, which obstructs the passage of air. Obstruction may also be caused by enlarged tonsils or adenoids. The obstruction causes snoring. If complete blockage occurs, breathing stops. This triggers the brain to restart breathing, and the person may gasp and wake briefly.

In central sleep apnoea, breathing stops because the chest and diaphragm muscles temporarily cease to work, probably due to a disturbance in the brain’s control of breathing. Causes include paralysis of the diaphragm and disorders of the brainstem. Snoring is not a main feature.People who are overweight may find losing weight helps.

Alcohol and sleeping drugs aggravate sleep apnoea.

In one treatment, air from a compressor is forced into the airway via a mask worn over the nose.

Night-time artificial ventilation may be needed.

Tonsillectomy, adenoidectomy, or surgery to shorten or stiffen the soft palate may be performed.... sleep apnoea

Health Indicator / Index

A characteristic of an individual, population or environment which is subjected to measurement and can be used to describe one or more aspects of the health of an individual or population (quality, quantity and time). A health index comprises a number of indicators.... health indicator / index

Human Development Index (hdi)

A composite index that measures the overall achievements in a country in three basic dimensions of human development— longevity, knowledge and a decent standard of living. It is measured by life expectancy, educational attainment and adjusted income per capita in purchasing power parity (PPP) US dollars. The HDI is a summary, not a comprehensive measure of human development.... human development index (hdi)

Index

In epidemiology and related sciences, this word usually means a rating scale, e.g. a set of numbers derived from a series of observations of specified variables.... index

Index Medicus

A monthly publication produced by the National Library of Medicine in the USA. The publication indexes leading biomedical literature from throughout the world. Indexing is by author and by subject.... index medicus

Apnoea Monitor

an electronic alarm that is activated by a sensor that responds to a baby’s respiratory movements. It can be used at home to monitor babies thought to be at risk of *sudden infant death syndrome.... apnoea monitor

Cardiac Index

the volume of blood pumped from the heart’s left ventricle divided by body surface area, expressed as litres per minute per square metre (l/min/m2). It is determined by heart rate and stroke volume index (the volume of blood pumped by the heart with each beat), and provides a normal range (2.5–4.0 l/min/m2) regardless of the size of the patient.... cardiac index

Cephalic Index

a measure of the shape of a skull, commonly used in *craniometry: the ratio of the greatest breadth, multiplied by 100, to the greatest length of the skull. See also brachycephaly; dolichocephaly.... cephalic index

Cervical Resistance Index

measurement of the resistance of the cervix during the passage of a series of metal (Hegar) dilators. Lack of resistance in a nonpregnant women may suggest cervical weakness when she has experienced a previous second-trimester pregnancy loss or if she has had previous surgery to the cervix, and may indicate *cervical cerclage in the event of future pregnancies.... cervical resistance index

Dermatology Life Quality Index

(DLQI) a validated questionnaire designed by Finlay in 1994 to assess the impact of skin diseases on psychological and social wellbeing. It is the most common *quality of life tool used as an endpoint in dermatology clinical trials. DLQI scores of more than 10 (indicating a severe impact on life) are required before biological treatments for psoriasis may be administered in the UK.... dermatology life quality index

Functional Recovery Index

an international index, published by the World Health Organization, that grades the degree of recovery after serious injury.... functional recovery index

Glycaemic Index

(GI) a ranking system measuring the effect carbohydrate (CHO) ingestion has on blood glucose levels. Glucose is used as the standard reference value (50 g glucose has a GI of 100). A portion of food containing 50 g CHO is ingested and the effect on blood glucose levels measured over a three-hour period and compared with the effect of 50 g of glucose. Foods with a low GI (<60), such as apples, yoghurt, and beans, are slowly absorbed, causing a lower and more prolonged increase in blood glucose levels, than foods with a high GI (>70), e.g. white bread, white rice, and potatoes. Low GI foods help with diabetes control and may be beneficial in the treatment of *polycystic ovary syndrome. The glycaemic load (GL) also takes into account the amount of food that is eaten: GL = (g CHO in food portion eaten × GI)/100.... glycaemic index

 labelling Index

the proportion of cells in a sample of tissue that are producing DNA. Cells that are synthesizing DNA take up tritiated thymidine, which shows up on an autoradiograph (see autoradiography) of the sample....  labelling index

Mitotic Index

the proportion of cells in a tissue that are dividing at a given time.... mitotic index

Obstructive Sleep Apnoea

(OSA, obstructive sleep apnoea syndrome, OSAS) a serious condition in which airflow from the nose and mouth to the lungs is restricted during sleep, also called sleep apnoea syndrome (SAS). It is defined by the presence of more than five episodes of *apnoea per hour of sleep associated with significant daytime sleepiness. Snoring is a feature of the condition but it is not universal. There are significant medical complications of prolonged OSA, including heart failure and high blood pressure. Patients perform poorly on driving simulators, and driving licence authorities may impose limitations on possession of a driving licence. There are associated conditions in adults, the *hypopnoea syndrome and the upper airways resistance syndrome, with less apnoea but with daytime somnolence and prominent snoring. In children the cause is usually enlargement of the tonsils and adenoids and treatment is by removing these structures. In adults the tonsils may be implicated but there are often other abnormalities of the pharynx, and patients are often obese. Treatment may include weight reduction or nasal *continuous positive airways pressure (nCPAP) devices, *mandibular advancement splints, or noninvasive ventilation. Alternatively *tonsillectomy, *uvulopalatopharyngoplasty, *laser-assisted uvulopalatoplasty, or *tracheostomy may be required.... obstructive sleep apnoea

Obstructive Sleep Apnoea Syndrome

(OSAS) see obstructive sleep apnoea.... obstructive sleep apnoea syndrome

Pressure Index

(PI) the ratio of the pressure in the posterior tibial artery to that in the brachial artery, which reflects the degree of arterial obstruction in the artery of the lower limb.... pressure index

Psoriasis Area Severity Index

(PASI) a semiobjective severity score for psoriasis, including measurement of surface area affected and the degree of erythema, induration, and scale. It is commonly used in clinical trials and to ration expensive treatments for psoriasis. Severe disease equates to scores over 10 and it is often interpreted with the *dermatology life quality index (DLQI) score.... psoriasis area severity index

Risk Of Malignancy Index

(RMI) a scoring system that combines ultrasound findings, menopausal status and age, and serum CA125 levels to give an estimate of the risk of malignancy in a woman with a mass in the Fallopian tubes or ovaries. If the total RMI score is <200 the risk of malignancy is considered to be low. If the total RMI score is >200 the chances of malignancy are raised and management should be planned with a gynaecological oncologist.... risk of malignancy index

Sleep Apnoea Syndrome

(SAS) see obstructive sleep apnoea.... sleep apnoea syndrome



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