Asclepias curassavica Health Dictionary

Asclepias Curassavica: From 1 Different Sources


Linn.

Family: Aristolochiaceae.

Habitat: Indigenous to the northern parts of southern Europe, Central and East-Central Europe; cultivated in the United States. A related sp., Asarum himalaicum, synonym A. canadense, is reported from the eastern Himalayas.

English: Asarbacca, Hazelwort, Wild Nard.

Unani: Asaaroon, Subul-e-Barri, Naardeen-Barri.

Folk: Tagar Ganthodaa.

Action: Brain and nervine tonic, diuretic, deobstructant and anti- inflammatory; used in bronchial spasm and in preparations of cephalic snuffs.

The volatile oil (0.7-4%) consists of asarone up to 50%, asaraldehyde 2-3%, methyleugenol 15-20%, with bornyl acetate, terpenes and sesquiterpenes. Asarone and its beta-isomer is found to be carcinogenic in animals. The rhizome, in addition, contains caffeic acid derivatives and flavonoids.

A related sp., Asarum canadense L., indigenous to North America and China, contains a volatile oil (3.5-

Family: Asclepiadaceae.

Habitat: Naturalized in many parts of India as an ornamental.

English: Curassavian Swallow- Wort, West Indian Ipecacuanha, Blood-Flower.

Ayurvedic: Kaakanaasikaa (substitute).

Folk: Kaakatundi (Kashmir).

Action: Spasmogenic, cardiotonic, cytotoxic, antihaemorrhagic, styptic, antibacterial. Various plant parts, as also plant latex, are used against warts and cancer. Root—used as an astringent in piles. Leaves—juice, antidysenteric, also used against haemorrhages. Flowers—juice, styptic. Alcoholic extract of the plant—cardiotonic.

An alcoholic extract of the Indian plant has been reported to contain a number of cardenolides, including calactin, calotropin, calotropagenin, coroglaucigenin, uzarigenin, asclepin, its glucosides and uzarin. Asclepin, the chief active principle, is spasmogenic and a cardiac tonic, having longer duration of action than digoxin (96 h in cat, as opposed to the 72 h of digoxin). Calotropin exhibits cytotoxic activity.

Pleurisy root of the U.S. is equated with Asclepias tuberosa. It is used for cold, flu and bronchitis in Western herbal medicine.

Toxic principles of the herb include galitoxin and similar resins, and glu- cofrugoside (cardenolide). Toxicity is reduced by drying.
Health Source: Indian Medicinal Plants
Author: Health Dictionary

Diaphoretic

A substance that increases perspiration, either by (1) dilating the peripheral blood vessels (Capsicum), (2) directly stimulating by drug action the nerves that affect the sweat glands (Asclepias tuberosa), or by (3) introducing a volatile oil into the bloodstream that performs both tasks (Asarum canadensis).... diaphoretic

Gymnema

Gymnema sylvestre

Asclepiadaceae

San: Mesasrngi, Madhunasini;

Hin: Gudmar, Merasimgi;

Ben: Merasingi;

Mal: Chakkarakolli, Madhunasini;

Tam: Sirukurumkay, Sakkaraikkolli;

Kan: Kadhasige;

Tel: Podapatra; Mar: Kavali

Importance: Gymnema, Australian Cowplant, Small Indian Ipecacuanha or Periploca of the woods is a woody climber. It is reported to cure cough, dyspnoea, ulcers, pitta, kapha and pain in the eyes. The plant is useful in inflammations, hepatosplenomegaly, dyspepsia, constipation, jaundice, haemorrhoids, strangury, renal and vesical calculi, helminthiasis, cardiopathy, cough, asthma, bronchitis, intermittent fever, amenorrhoea, conjuctivitis and leucoderma. The fresh leaves when chewed have the remarkable property of paralysing the sense of taste for sweet and bitter substance for some time (Warrier et al, 1995). The drug is described as a destroyer of madhumeha (glycosuria) and other urinary disorders. Root has long been reputed as a remedy for snakebite. Leaves triturated and mixed with castor oil are applied to swollen glands and enlargement of internal viscera as the liver and spleen (Nadkarni, 1954). The drug is used to strengthen the function of heart, cure jaundice, piles, urinary calculi, difficult micturition and intermittent fevers (Sharma,1983). The drug enters into the composition of preparations like Ayaskrti, Varunadi kasaya, Varunadighrtam, Mahakalyanakaghrtam, etc. They suppress the activity of taste of tongue for sweet taste and for this reason it was considered that it destroys sugar, hence the name Madhunashini or Gurmar and has been prescribed as an anti-diabetic. The crude drug as well as its dried aqueous extract is mainly used in bronchial troubles.

Distribution: It is a tropical climber. It mainly grows in Western Ghats, Konkan, Tamil Nadu and some parts of Bihar. The plant is cultivated in plains of India but the drug is mainly important from Afghanistan and Iran.

Botany: Gymnema sylvestre (Retz.)R. Br. syn. Asclepias germinata Roxb. belonging to the family Asclepiadaceae is a large, woody much branched climber with pubescent young parts. Leaves are simple, opposite, elliptic or ovate, more or less pubescent on both sides, base rounded or cordate. Flowers are small, yellow and arranged in umbellate cymes. Fruits are slender and follicles are upto 7.5cm long (Warrier et al, 1995).

Two allied species, G. hirsutum found in Bundelkh and Bihar and Western Ghats and G. montanum growing wild in Eastern Ghats and Konkan are also used for the same purpose and are also called “Gurmar” (Thakur et al, 1989).

Agrotechnology: The plant can be propagated both by seeds and stem cuttings. Seedlings are to be raised in polybags. Pits of size 50cm cube are to be taken, filled with 10kg dried cowdung or FYM and covered with topsoil. On these pits about 3-4 months old seedlings are to be transplanted from polybags. Trailing can be facilitated by erecting poles and tying the plants to the poles. The plant will attain good spread within one year. Regular weeding, irrigation and organic manure application are beneficial. The plant is not attacked by any serious pests or diseases. Leaves can be collected from the first year onwards at an internal of one week. This can be continued for 10-12 years. Fresh or dried leaves can be marketed (Prasad et al, 1997).

Properties and activity: Nonacosane and hentriacontane were isolated from the hexane extract of leaves. An attempt to isolate nitrogenous compounds led to the isolation of amino acids such as leucine, iso-leucine, valine, allanine and - amynobutyric acid. Isolation of trimethyl amine oxide was of particular interest. An alkaloid gynamine which is a trace constituent was isolated and identified (Sinsheimer et al, 1967). Antisweet constituent of the leaves has been found to be a mixture of triterpene saponins. These have been designated as gymnemic acids A,B,C and D which have the gymnemagenin and gymnestrogenins as the aglycones of gymnemic acid A and B and gymnemic acid C and D respectively. These are hexahydroxy triterpenes the latter being partially acylated. The sugar residues are glucuronic acid and galacturonic acid while ferulic and angelic acids have been attached as the carboxylic acid.

Chewing of leaves reduces sensitivity to sweet substances. Effects of gymnema extracts had been variable. While verifying the effect of G. sylvestre leaves on detoxification of snake venom, it has been reported that a toxic component of venom ATP and gymnemate bind at the same site inhibiting venom ATP-ase. The active principles which have been identified as glycosides (7 gymnemic acids) suggest that the topical and selective anaesthetic effect of the plant might result from the competition of the receptor sites between glycosides and the sweet substances (Warren et al, 1969). The leaves are antidiabetic and insulinotropic. Gymnemic acid is antiviral. The plant is bitter, astringent, acrid, thermogenic, antiinflammatory, anodyne, digestive, liver tonic, emetic, diuretic, stomachic, stimulant, anthelmintic, alexipharmic, laxative, cardiotonic, expectorant, antipyretic and uterine tonic.... gymnema

Holostemma Annularis

(Roxb.) K. Schum.

Synonym: H. ada-kodien Schult. H. rheedii Wall. Asclepias annularis Roxb.

Family: Asclepiadaceae.

Habitat: Tropical Himalayas and Western Peninsula. Cultivated in Dharmapuri district of Tamil Nadu.

Ayurvedic: Ark-pushpi.

Siddha/Tamil: Palay-keerai.

Action: Roots—used in orchitis, spermatorrhoea, also as laxative. Roots are used as Jivanti in Kerala (See also Leptadenia reticulata.)

The tubers contain protein (5.510%). It gave alpha-amyrin, lupeol and beta-sitosterol. Aspartic acid, glycine, serine, threonine and valine were detected chromatographically.

The bark gave alpha-amyrin, lupeol and beta-sitosterol.... holostemma annularis

Pilocarpine

A plant alkaloid and the primary bioactive substance reducible from Pilocarpus spp. (Jaborandi leaves). It is an almost pure parasympathomimetic (cholinergic), inducing lowered blood pressure and stimulating glandular secretions...EVERYWHERE. It stimulates sweating as well, a sympathetic cholinergic response. Anyway, it is used in eye drops these days to contract the pupil, lower ocular fluid pressure and take some of the stress off glaucoma. The refined alkaloid is better in the eyes, but the dried leaves are the usual complex agents of herb use and have some therapeutic values in low doses. Good Lobelia or Asclepias will work similarly and are both safer, fresher and more predictable as botanicals.... pilocarpine

Pleurisy Root

Asclepias tuberosa. N.O. Asclepiadaceae.

Synonym: Butterfly Weed, Tuber Root, Wind Root.

Habitat: Moist, loamy soil. Indigenous to U.S.A

Features ? Stem two to three feet high, contains milky juice. Root, wrinkled longitudinally, light brown outer surface, whitish internally ; fracture tough, irregular. Rootstock knotty, faintly ringed. Acrid taste.

Part used ? Root.

Action: Diaphoretic, expectorant, antispasmodic.

Chest complaints; acts directly on the lungs, and stimulates sweat glands. Relaxes capillaries, relieving strain on heart and lungs. Reduces pain and assists breathing in pleurisy. Infusion of 1 ounce of the powdered root with 1 pint of boiling water is taken in wineglass doses, to which a teaspoonful of composition powder (Myrica compound) may be added with advantage.... pleurisy root

Neuralgia, Intercostal

 Pain along a sensory nerve serving the chest, without loss of sensation and power of movement. Differs from neuritis in which nerves are inflamed.

Causes: all kinds of infective diseases. Rheumatism, bad teeth, bony spinal lesions, gall stone, liver disorder, thickening of pleura, fractured ribs, shingles – see: SHINGLES. In simple cases a cup of Chamomile tea may suffice. Persistent cases require one of the following alternatives.

Alternatives. Decoction. Combine equal parts: Black Cohosh, Jamaica Dogwood (or White Willow), Pleurisy root. 1 heaped teaspoon to each cup water gently simmered 20 minutes. Half-1 cup thrice daily. Formula. Cramp bark 2; Black Cohosh 1; Valerian 1. Pinch of Cayenne or few drops Tincture Capsicum. Dose: Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. Powders: 500mg (two 00 capsules or one- third teaspoon). Thrice daily.

Neuralgia associated with bronchi and lung: Formula: Cramp bark 2; Pleurisy root 2; Liquorice half. Dose: as above.

Practitioner. Tincture Gelsemium BPC (1973). 0.3ml (5 drops) in water as necessary.

Dr Finlay Ellingwood. Tincture Pleurisy root (Asclepias). 20 drops, every 2 hours.

Topical. Poultice: Chamomile, Hops, Linseed or Bran. Acute cases (cold), chronic cases (hot). Grated or bruised Horseradish root. Evening Primrose oil. Hot Cider vinegar. Tincture Arnica or Hypericum. Aromatherapy. 2 drops each: Juniper, Lavender, Chamomile, to 2 teaspoons vegetable oil. Massage. Diet, vitamins, minerals. Same as for general neuralgia. Cold water packs. ... neuralgia, intercostal




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