A naturally occurring painkiller which is produced by the PITUITARY GLAND as part of a pro-hormone (pre-pro-opianomelanocortin). It is an agonist at opioid receptors, and its release is stimulated by pain and stress. (See ENDORPHINS.)
(endomorphin) n. one of a group of chemical compounds, similar to the *encephalins, that occur naturally in the brain and have pain-relieving properties similar to those of the opiates. They are also responsible for sensations of pleasure. The endorphins are derived from a substance found in the pituitary gland known as beta-lipotrophin; they are thought to be concerned with controlling the activity of the endocrine glands.... endorphin