A muscle-relaxant drug that is used to relieve muscle spasm and stiffness due to brain or spinal cord injury, stroke, or neurological disorders such as multiple sclerosis. Adverse effects of baclofen include drowsiness and muscle weakness; these side effects can be limited, however, by increasing the dose of the drug gradually.
A powerful muscle-relaxant used for patients with chronic severe spasticity – increased muscle rigidity – resulting from disorders such as CEREBRAL PALSY, MULTIPLE SCLEROSIS (MS) or traumatic partial section of the SPINAL CORD. Important adverse effects include SEDATION, HYPOTONIA and DELIRIUM.
n. a skeletal *muscle relaxant drug administered to relieve spasm resulting from injury or disease of the brain or spinal cord, including cerebral palsy and multiple sclerosis. Side-effects include dizziness, drowsiness, and nausea.
an agent that reduces tension in voluntary muscles. Drugs such as *baclofen, *dantrolene, and *diazepam are used to relieve skeletal muscular spasms in various spastic conditions, parkinsonism, and tetanus. The drugs used to relax voluntary muscles during the administration of anaesthetics in surgical operations act by blocking the transmission of impulses at neuromuscular junctions. Nondepolarizing muscle relaxants, e.g. *atracurium besilate, cisatracurium, pancuronium, and rocuronium, bind to receptor sites normally occupied by acetylcholine; depolarizing muscle relaxants, e.g. *suxamethonium, mimic the action of acetylcholine but *depolarization is prolonged.... muscle relaxant
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