Habitat: Rajasthan, Madhya Pradesh, Assam, Andhra Pradesh, Karnataka.
English: Indian Bdellium, Gum Guggul.Ayurvedic: Guggul, Devadhoop, Kaushika, Pur, Mahishaaksha, Palankash, Kumbha, Uluukhala.Unani: Muqallal yahood, Muql, Bu-e-JahudaanSiddha/Tamil: Erumaikan Kungiliyam.Action: Oleo-gum-resin—used for reducing obesity and in rheumatoid arthritis, osteoarthritis, sciatica.
Key application: In the treatment of hyperlipidemia, hypercholestero- laemia and obesity. (WHO.)Guggulipid is hypocholesteremic. Guggul resin contains steroids—gug- glsterones Z and E, guggulsterols IV, diterpenoids; volatile oil, including other constituents, contains a terpene hydrocarbon cembrene A. E- and Z- guggulsterones are characteristic constituents, which distinguish C. mukul from other Commiphore sp.Guggul resin increases catechola- mine biosynthesis and activity in cholesterol-fed rabbits, inhibits platelet aggregation, exhibits anti-inflammatory activity and appears to activate the thyroid gland in rats and chicken. Z- guggulsterone may increase uptake of iodine by thyroid gland and increase oxygen uptake in liver and bicep tissues. (Planta Med 1984,1, 78-80.)The gum is also used in hemiplegia and atherosclerotic disorders; as a gargle in pyrrhoea aveolaris, chronic tonsilitis and pharyngitis. Fumes are recommended in hay fever, chronic bronchitis and nasal catarrh.Oleo-gum resin of Balsamodendron caudatum is also equated with Guggul in Siddha medicine.Dosage: Oleo-gum-resin—2-4 g (API Vol. I.) 500 mg to 1 g (CCRAS.)