Basophilic Health Dictionary

Boiss.

Family: Euphorbiaceae.

Habitat: Western Himalaya from Kumaon to Nepal.

Ayurvedic: Snuhi, Snuk, Sehunda, Gudaa (Substitutes.) (Adhogudaa of Ayurvedic medicine and Bana- muuli of folk medicine have been equated with Euphorbia acaulis Rox.)

Unani: Thuuhar

Folk: Thor, Surai.

Action: Latex—cathartic, anthelmintic.

The latex yield euphol, cycloeu- calenol, an inseparable mixture of four tetra-and four tri-esters of macrocyclic diterpene ingenol, octacosanol, tetra- cosanol, beta-sitosterol, stigmasterol, alpha-amyrin and campesterol. The plant gave ingenol.

The latex is a valuable source of in- genol esters. Ingol is a macrocyclic diterpene and is of therapeutic interest due to its antileukemic properties. Fractionation of the latex gave ingol- 12-acetate and 8-tigloyl-12-acetate. The acylation of ingol-12-acetate yielded derivatives which inhibit the growth of the basophilic leukaemia cells in rats.... euphorbia royleana

1. n. a variety of white blood cell distinguished by a lobed nucleus and the presence in its cytoplasm of coarse granules that stain purple-black with *Romanowsky stains. Basophils are capable of ingesting foreign particles and contain *histamine and *heparin. There are normally 30–150 × 106 basophils per litre of blood. See also polymorph. 2. (basophilic) adj. describing any cell that stains well with basic dyes. For example, certain cells in the anterior pituitary gland are basophilic.... basophil

n. a rare form of chronic inflammatory disorder due to the defective destruction of phagocytosed bacteria. It is characterized by the formation of soft yellow plaques and nodules composed of foamy macrophages containing basophilic cytoplasmic inclusions (Michaelis–Gutmann bodies). Malakoplakia occurs most commonly in the urinary tract but can also occur in the skin.... malakoplakia

n. a nucleated cell that forms part of the series giving rise to the red blood cells and is normally found in the blood-forming tissue of the bone marrow. Normoblasts pass through three stages of maturation: early (or basophilic), intermediate (or polychromatic), and late (or orthochromatic) forms. See also erythroblast; erythropoiesis.... normoblast

a dye used in microscopy for staining basophilic substances in tissue specimens.... toluidine blue