n. a drug that is used to treat hyperlipidaemia that fails to respond to diet (see fibrates). Possible side-effects include skin rashes, nausea and vomiting, and muscle pain.
pl. n. a class of drugs, chemically related to fibric acid, that are capable of reducing concentrations of triglycerides in the blood (see hypertriglyceridaemia); they may also reduce plasma *low-density lipoproteins and they tend to raise the levels of the beneficial *high-density lipoproteins. Fibrates are used for treating hyperlipidaemia; they include *bezafibrate, ciprofibrate, fenofibrate, and *gemfibrozil. Fibrates can have adverse effects on muscle (see myositis).... fibrates