Brachytherapy Health Dictionary

Treatment of a cancerous tumour by inserting radioactive material into the growth or into neighbouring tissue. Using this method, also called brachytherapy, radiation can be targeted at the diseased area.

Radioactive material (usually artificial radioisotopes) contained in wires, small tubes, or seeds is then implanted into or near the diseased tissue under general anaesthesia. The material is left in place for variable amounts of time depending on the radioactive substance and the tumour being treated. (See also intracavitary therapy; radiotherapy.)... interstitial radiotherapy

Treatment of a cancerous tumour in a body cavity or the cavity of a hollow organ by placing a radioactive implant or anticancer drugs within the cavity. Also called brachytherapy, intracavitary radiotherapy is mainly used to treat cancers of the uterus and cervix (see uterus, cancer of; cervix, cancer of). If implants (usually in the form of artificial radioisotopes embedded in wires or small tubes) are used, they are left there for a period of time.

The technique may be used to treat a malignant effusion (a collection of fluid that contains cancerous cells). A needle, sometimes with a catheter attached, is passed through the wall of the abdomen or the chest into the abdominal cavity or pleural cavity (the space around the lungs). As much of the fluid as possible is withdrawn from the cavity before anticancer drugs are injected directly into it. (See also interstitial radiotherapy.)... intracavitary therapy

n. a radioactive isotope of the metallic element iridium. It is the most common source used for intracavitary *brachytherapy. Symbol: Ir-192.... iridium-192

a malignant tumour (*carcinoma) of the prostate gland, a common form of cancer in elderly men. In most men it progresses slowly over many years and gives symptoms similar to those of benign enlargement of the prostate (see prostate gland). Before it was possible to test for *prostate specific antigen (PSA), the tumour had often invaded locally, spread to regional lymph nodes, and metastasized to bone before clinical presentation. By checking elevated levels of PSA or *PCA3, prostate cancer can be detected 5–10 years before the tumour would present symptomatically. If the disease is confined to the prostate, the patient may be offered active surveillance or radical *prostatectomy, radical radiotherapy, or *brachytherapy; *cryotherapy or *HIFU are available in specialized centres. In elderly patients, it may be enough to monitor the tumour growth. If the disease is outside the prostate, androgen deprivation therapy may be used; this may be achieved by *gonadorelin analogues, *anti-androgens, surgical castration, or oestrogen therapy.... prostate cancer

n. therapeutic radiology: the treatment of disease with penetrating radiation, such as X-rays, beta rays, or gamma rays, which may be produced by machines or given off by radioactive isotopes. Beams of radiation may be directed at a diseased part from a distance (see teletherapy), or radioactive material, in the form of needles, wires, or pellets, may be implanted in the body (see brachytherapy). Many forms of cancer are destroyed by radiotherapy.... radiotherapy