the distance (in millimetres) between the surface and the deepest extent of a malignant *melanoma. The measurement is the best prognostic indicator in melanoma; tumours that are less than 0.76 mm thick have a 5-year survival in well over 90% of patients. [A. Breslow (1928–80), US pathologist]
Ultrasound scanning performed in early pregnancy in order to identify fetuses at high risk of chromosomal abnormalities such as Down’s syndrome. The scan investigates the nuchal fold, an area of skin at the back of the neck. Excessive thickness of the skin is an indicator of possible chromosomal abnormalities.... nuchal thickness scan