An instrument constructed on the principle of the telescope, which on introduction into the mouth is passed down through the LARYNX and TRACHEA and enables the observer to see the interior of the larger bronchial tubes. The bronchoscope has largely been superseded by ?breoptic bronchoscopy. (See ENDOSCOPE.)
n. an instrument used to look into the trachea and bronchi. In addition to the rigid tubular metal type, used for many years, there is now a narrower flexible *fibreoptic instrument with which previously inaccessible bronchi can be inspected. With either instrument the bronchial tree can be washed out (see bronchoalveolar lavage) and samples of tissue and foreign bodies can be removed with long forceps. —bronchoscopy n.
n. failure of part of the lung to expand. This occurs when the cells lining the air sacs (alveoli) are too immature, as in premature babies, and unable to produce the wetting agent (surfactant) with which the surface tension between the alveolar walls is overcome. It also occurs when the larger bronchial tubes are blocked from within by retained secretions, inhaled foreign bodies, or bronchial cancers, or from without by enlarged lymph nodes, such as are found in patients with tuberculosis and lung cancers. The lung can usually be helped to expand by physiotherapy and removal of the internal block (if present) via a *bronchoscope, but prolonged atelectasis becomes irreversible.... atelectasis
(BAL) a method of obtaining cellular material from the lungs that is used particularly in the investigation and monitoring of interstitial lung disease and in the investigation of pulmonary infiltrates in immunosuppressed patients. A saline solution is infused into the lung, via a bronchoscope, and immediately removed. Examination of the cells in the lavage fluid may help to identify the cause of interstitial lung disease. The combination of cytological and microbiological examination can lead to a very high rate of diagnostic accuracy in such conditions as *Pneumocystis jiroveci pneumonia.... bronchoalveolar lavage
(PDT, photoradiation therapy, phototherapy, photochemotherapy) 1. a treatment for some types of superficial cancers. A light-sensitive agent (porfimer sodium [Photofrin] or temoporfin [Foscan]) is injected into the bloodstream and remains in cancer cells for a longer time than in normal cells. Exposure to laser radiation produces an active form of oxygen that destroys the treated cancer cells. The laser radiation can be directed through a fibreoptic bronchoscope into the airways, through a gastroscope into the oesophagus, or through a cystoscope into the bladder. PDT causes minimal damage to healthy tissue, but as it cannot pass through more than about 3 cm of tissue, it is restricted to treating tumours on or just under the skin or on the lining of internal organs. Photodynamic therapy makes the skin and eyes sensitive to light for six weeks or more after treatment. 2. a treatment for wet age-related *macular degeneration that involves the intravenous injection of a light-sensitive agent (verteporfin, Visudyne) which passes to the abnormal leaking blood vessels in the retina. The agent is activated when a cold laser light is directed at the macula, sealing the abnormal vessels and thus preventing further leakage and macular damage. The effect is to limit visual loss and stabilize vision.... photodynamic therapy