Rabbit’s foot fern (Polypodium aureum).Plant Part Used: Leaf (fern frond).Dominican Medicinal Uses: The leaf is traditionally prepared as an infusion and taken orally for the common cold, flu and upper respiratory tract infections.Safety: In a human clinical trial of the plant extract, no toxic or adverse effects were reported.Contraindications: Insufficient information identified in the available literature.Drug Interactions: Insufficient information identified in the available literature.Clinical Data: The plant extract has been studied in one human clinical trial for its photoprotective effects and was recommended as a potential therapy.Laboratory & Preclinical Data: Plant extracts have shown antiparasitic, anti-inflammatory, antioxidant, immunosuppressant effects in animal studies. Isolated constituents (calagualine) or plant extracts have shown anti-tumor, antiviral, immunomodulatory and leukotriene formation inhibition activity in vitro.