Calc Health Dictionary

Calc: From 1 Different Sources


Calcium

The metallic element present in chalk and other forms of lime. The chief preparations used in medicine are calcium carbonate (chalk), calcium chloride, calcium gluconate, calcium hydroxide (slaked lime), liquor of calcium hydroxide (lime-water), calcium lactate, and calcium phosphate. Calcium gluconate is freely soluble in water and is used in conditions in which calcium should be given by injection.

Calcium is a most important element in diet; the chief sources of it are milk and cheese. Calcium is especially needed by the growing child and the pregnant and nursing mother. The uptake of calcium by the baby is helped by vitamin D (see APPENDIX 5: VITAMINS). A de?ciency of calcium may cause TETANY, and an excess may result in the development of CALCULI (stones) in the KIDNEYS or gallbladder (see LIVER).

The recommended daily intakes of calcium are: 500 mg for children, 700 mg for adolescents, 500–900 mg for adults and 1,200 mg for pregnant or nursing mothers.... calcium

Calculus

A concretion formed in any part of the body usually compounds of salts of organic or inorganic acids... calculus

Calcaneus

The heel-bone or os calcis, and the largest bone in the foot.... calcaneus

Calciferol

This is an outdated term for ergocaliciferol or vitamin D2 (see APPENDIX 5: VITAMINS).... calciferol

Calcinosis

Abnormal deposition of CALCIUM in the body tissue.... calcinosis

Calcitonin

A hormone, produced by the THYROID GLAND, which is involved in the metabolism of bone. Acting to lower concentrations of CALCIUM and PHOSPHATES in the blood, calcitonin is given by injection in the treatment of some patients with HYPERCALCAEMIA (especially when associated with malignant disease). In severe cases of PAGET’S DISEASE OF BONE it is used mainly for pain relief, but also relieves some of the neurological complications such as deafness.... calcitonin

Calcicosis

Calcicosis is a traditional term applied to disease of the lung caused by the inhalation of marble dust by marble-cutters.... calcicosis

Calcium-channel Blockers

Calcium-channel blockers inhibit the inward ?ow of calcium through the specialised slow channels of cardiac and arterial smooth-muscle cells. By thus relaxing the smooth muscle, they have important applications in the treatment of HYPERTENSION and ANGINA PECTORIS. Various types of calcium-channel blockers are available in the United Kingdom; these di?er in their sites of action, leading to notable di?erences in their therapeutic effects. All the drugs are rapidly and completely absorbed, but extensive ?rst-pass metabolism in the liver reduces bioavailability to around one-?fth. Their hypotensive e?ect is additive with that of beta blockers (see BETA-ADRENOCEPTOR-BLOCKING DRUGS); the two should, therefore, be used together with great caution – if at all. Calcium-channel blockers are particularly useful when beta blockers are contraindicated, for example in asthmatics. However, they should be prescribed for hypertension only when THIAZIDES and beta blockers have failed, are contraindicated or not tolerated.

Verapamil, the longest-available, is used to treat angina and hypertension. It is the only calcium-channel blocker e?ective against cardiac ARRHYTHMIA and it is the drug of choice in terminating supraventricular tachycardia. It may precipitate heart failure, and cause HYPOTENSION at high doses. Nifedipine and diltiazem act more on the vessels and less on the myocardium than verapamil; they have no antiarrhythmic activity. They are used in the prophylaxis and treatment of angina, and in hypertension. Nicardipine and similar drugs act mainly on the vessels, but are valuable in the treatment of hypertension and angina. Important di?erences exist between di?erent calcium-channel blockers so their use must be carefully assessed. They should not be stopped suddenty, as this may precipitate angina. (See also HEART, DISEASES OF.)... calcium-channel blockers

Calculi

The general name given to concretions in, for example, the URINARY BLADDER, KIDNEYS or gall-bladder (see LIVER).... calculi

Staghorn Calculus

A branched renal stone formed in the image of the collecting system of the kidney (see KIDNEYS). It ?lls the calyces and pelvis and is commonly associated with an infection of the urine, particularly Proteus vulgaris. The calculus may lead to pyonephrosis and an ABSCESS of the kidney.... staghorn calculus

Calcification

The deposition of calcium salts in body tissues that is part of the normal process of bone and teeth formation and the healing of fractures.

Calcification also occurs in injured muscles, in arteries affected by atherosclerosis, and when blood calcium levels are raised by disorders of the parathyroid glands.... calcification

Calcipotriol

A derivative of vitamin D, used in topical preparations for treating the skin disorder psoriasis.... calcipotriol

Calcification

The deposition of CALCIUM salts in body tissues, normally BONE and TEETH, though abnormal deposits can occur in damaged muscles or the walls of arteries.... calcification

Calcio

Calcium; this powdered mineral is often added as a supplement to herbal and other medicinal preparations and is often used in the treatment of anemia.... calcio

Calcium Gluconate

A salt of the element CALCIUM used to treat de?ciency of the mineral or to prevent osteoporosis (see BONE, DISORDERS OF). Tablets can be obtained without a doctor’s prescription. It is used intravenously to treat low calcium levels causing symptoms in newborn babies.... calcium gluconate

Renal Calculi

Calculi relating to kidney... renal calculi

Calcification, Dental

The deposition of calcium salts in developing teeth. Primary teeth begin to calcify in a fetus at between 3 and 6 months gestation; calcification of permanent teeth (other than the wisdom teeth) begins between birth and 4 years. Abnormal calcification occurs in amelogenesis imperfecta, an inherited disorder of the enamel (see hypoplasia, enamel), and can also result from the absorption of high levels of fluoride (see fluorosis).... calcification, dental

Calculus, Dental

A hard, crust-like deposit (also known as tartar) found on the crowns and roots of the teeth. Calculus forms when mineral salts in saliva are deposited in existing plaque. Supragingival calculus is a yellowish or white deposit that forms above the gum margin, on the crowns of teeth near the openings of salivary gland ducts. Subgingival calculus forms below the gum margin and is brown or black. Toxins in calculus cause gum inflammation (see gingivitis), which may progress to destruction of the supporting tissues (see periodontitis). Calculus is removed by professional scaling. Attention to oral hygiene reduces recurrence.... calculus, dental

Calculus, Urinary Tract

A stone in the kidneys, ureters, or bladder formed from substances in urine.

Most urinary tract stones are composed of calcium oxalate or other salts crystallized from the urine. These may be associated with a diet rich in oxalic acid (found in leafy vegetables and coffee); high levels of calcium in the blood as a result of hyperparathyroidism; or chronic dehydration. Other types of stone are associated with gout and some cancers. An infective stone is usually a result of chronic urinary tract infection.

In developing countries, bladder stones usually occur as a result of dietary deficiencies. In developed countries, they are usually caused by an obstruction to urine flow from the bladder and/or a longstanding urinary tract infection.

The most common symptom of a stone in the kidney or ureter is renal colic (a severe pain in the loin) that may cause nausea and vomiting. There may be haematuria (blood in the urine). A bladder stone is usually indicated by difficulty in passing urine. The site of the stone can usually be confirmed by intravenous or retrograde urography.

Renal colic is treated with bed rest and an opioid analgesic (painkiller).

With an adequate fluid intake, small stones are usually passed in the urine without problems.

The first line of treatment for larger stones is lithotripsy, which uses ultrasonic or shock waves to disintegrate the stones.

Alternatively, cytoscopy can be used to crush and remove stones in the bladder and lower ureter.

In some cases, surgery may be needed.... calculus, urinary tract

Acamprosate Calcium

a drug used, in conjunction with counselling, for the maintenance of sobriety. Patients must already be abstinent at the beginning of treatment. The most common side-effect is diarrhoea.... acamprosate calcium

Calcar

n. a spurlike projection. The calcar avis is the projection in the medial wall of the lateral ventricle of the brain.... calcar

Calcineurin Inhibitors

drugs that act by inhibiting the calcium-dependent protein *phosphatase calcineurin, an enzyme that initiates a sequence of events that bring about activation of T *lymphocytes. The group includes *ciclosporin and *tacrolimus, which are major maintenance immunosuppressants used in transplantation. Topical calcineurin inhibitors (e.g. tacrolimus, pimecrolimus [Elidel]) are used in the treatment of eczema when topical steroids have failed or are contraindicated. Stinging is a common transient side-effect, and reactivation of infections may occur.... calcineurin inhibitors

Calciphylaxis

n. calcific uraemic arteriolopathy: a rare and often fatal complication of end-stage renal failure associated with small vessel calcification, intractable skin ulceration, and a high risk of septic complications.... calciphylaxis

Calcitriol

n. 1,25-dihydroxycholecalciferol: the final and most metabolically active form of vitamin D3. It is formed in the kidney by the addition of two hydroxy (?OH) groups to the basic vitamin D molecule, which itself is produced in the skin from 7-dehydrocholesterol or ingested in certain foods. Calcitriol is given to raise blood calcium levels in patients with severe kidney disease and to treat postmenopausal osteoporosis. It is also used as an ointment to treat psoriasis.... calcitriol

Calcium-channel Blocker

(calcium antagonist) a drug that inhibits the influx of calcium ions into cardiac and smooth-muscle cells; it therefore reduces the strength of heart-muscle contraction, reduces conduction of impulses in the heart, and causes *vasodilatation. Calcium-channel blockers, which include *amlodipine, *diltiazem, *nicardipine, *nifedipine, and *verapamil, are used to treat angina and high blood pressure.... calcium-channel blocker

Calcium Pyrophosphate Deposition Disease

a condition in which calcium pyrophosphate is deposited in joints. The most common manifestation is *pseudogout, marked by acute pain, redness, and swelling resembling gout. Alternatively it may be asymptomatic in association with *chondrocalcinosis seen on X-ray, it may occur with osteoarthritis in the affected joint, or there may be chronic inflammation of the joint.... calcium pyrophosphate deposition disease

Calcium Score

a quantification of the amount of calcium seen in the coronary arteries on a CT scan, calcium being a marker of severe coronary artery disease.... calcium score

Calculosis

n. the presence of multiple calculi (stones) in the body. See calculus.... calculosis

Dystrophic Calcification

the calcification of injured or necrotic tissue in the absence of systemic *hypercalcaemia. Dystrophic calcification is a characteristic feature in some cancers of the breast, ovary, and thyroid gland. Compare metastatic calcification.... dystrophic calcification

Metastatic Calcification

the calcification of otherwise normal tissues in patients with *hypercalcaemia. Compare dystrophic calcification.... metastatic calcification

Topical Calcineurin Inhibitors

see calcineurin inhibitors.... topical calcineurin inhibitors



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