n. a drug of the *fluoropyrimidine class that is used in treatment of advanced or metastatic colorectal cancer, stomach cancer, and breast cancer. Side-effects may include blood disorders (see myelosuppression) and mouth ulcers.
(hand–foot syndrome) a skin reaction marked by redness, numbness, and desquamation of the palms of the hands and soles of the feet. It can be caused by many chemotherapy drugs, particularly fluorouracil and capecitabine, and tyrosine kinase inhibitors. Treatment requires cessation of the drug.... palmoplantar erythrodysaesthesia
n. a drug that requires metabolism in the liver before becoming biologically active. Examples are *carbimazole, which is metabolized to the pharmacologically active compound methimazole; and *capecitabine, which is metabolized to *fluorouracil.... prodrug
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