Cardiotonic Health Dictionary

Cardiotonic: From 3 Different Sources


Keeping the heart functioning normally
Health Source: Herbal Medical
Author: Health Dictionary
A substance that strengthens or regulates heart metabolism without overt stimulation or depression. It may increase coronary blood supply, normalize enervation, relax peripheral arteries (decreasing back-pressure on the valves), or decrease adrenergic stimulation. Examples: Crataegus, Selenicereus.
Health Source: Medicinal Plants Glossary
Author: Health Dictionary

Ashoka

Saraca asoca

Caesalpiniaceae

San:Asoka, Gatasokah;

Hin:Asok, Asoka; Ben:Ashok; Mal:Asokam;

Tam: Asogam;

Kan:Asokada, Aksunkara;

Tel: Asokamu, Vanjalamu

Importance: Ashoka, the sacred tree of Hindus and Buddhists, possesses varied medicinal uses. The bark is useful in dyspepsia, fever, dipsia, burning sensation, visceromegaly, colic, ulcers, menorrhagia, metropathy, leucorrhoea and pimples. The leaf juice mixed with cumin seeds is used for treating stomachalagia. The floweres are considered to be uterine tonic and are used in vitiated conditions of pitta, syphilis, cervical adinitis, hyperdipsia, burning sensation, haemorrhoids, dysentery, scabies in children and inflammation. The well-known Ayurvedic preparations are ”Ashokarishta” and “Ashokaghrita”. Ashokarishta is prescribed in leucorrhoea, haematuria, menorrhagia and other diseases of genitourinary system of females.

Distribution: Ashoka is found almost throughout India, except North-Western India, upto 750m. It is also found in the Andaman Islands.

Botany: Saraca asoca (Roxb.) de Wilde. syn. S. indica auct. non Linn. is a medium sized evergreen tree growing upto 9m height with numerous spreading and drooping glabrous branches. Leaves are pinnate, 30-60cm long having 2-3 pairs of lanceolate leaflets. Flowers are orange or orange yellow, arranged in dense corymbs and very fragrant. Fruits are flat black pods, leathery and compressed with 4-8 seeds/pod. Seeds are ellipsoid oblong and compressed. The bark is dark brown to grey or black with a warty surface. The thickness varies from 5mm to 10mm. The entire cut surface turns reddish on exposure to air. Polyalthia longifolia (Annonaceae) is equated with the name Asoka by some (Kapoor & Mitra, 1979; Chunekar, 1982) and is often used as an adulterant of the genuine Asoka bark or as a substitute (Warrier et al,1996).

Agrotechnology: Asoka grows well in areas with well distributed rainfall and in slightly shady areas. Asoka requires soil rich in organic mater and moisture. The best season of planting is June-July. It is also grown in summer, if irrigation facilities are available. The plant is seed propagated. Seeds are formed usually during February-April. Seeds are collected when they are ripen and fall down and are sown after soaking in water for 12 hours on the prepared beds. Seeds germinate within 20 days. The seeds are then planted in polybags. 2-month-old seedlings from the polybags are used for transplanting. Square shaped pits of 60cm depth are taken at 3m spacing and filled with topsoil, sand and dried cowdung. On this the seedlings are planted. Application of FYM at 10kg/tree/year is highly beneficial. Chemical fertilisers are not usually applied. Irrigation during summer months is essential. No serious pests or diseases are generally noted in this crop. If properly cultivated, Asoka can be cut after 20 years and the bark collected. It is cut at a height of 15cm from the soil level. If given irrigation and fertilisers, the cut wood will sprout again and harvested again after 5 years. This can be continued. When it is difficult to cut the tree, the bark can be peeled off from one side first. When the bark grows and cover that part, the other side can be peeled off. This is also continued (Prasad et al, 1997; Karshakasree, 1998).

Properties and activity: Flowers give -sitosterol, flavonoids and flavone glycosides-quercetin, kaempferol-3-O- -D- glucoside, quercetin-3-O- -D-glucoside. The anthocyanins present are pelargonidin-3, 5-diglucoside and cyanadin-3, 5-diglucoside. Bark yields catechol and sterols-(24)-24-methyl cholest-5-en-3 -ol, (22E, 24)-24-ethylcholesta-5, 22-dien-3 -ol and (24)-24-ethyl cholest-5-en-3 -ol, a wax containing n-alkanes, esters and free primary alcohols. Alcoholic extract and glycoside P2 from stem bark is oxytoxic. Aerial part is CNS active, hypothermic, CNS depressant and diuretic. Stem bark is anticancerous, has spasmodic action on rabbit intestine and cardiotonic action in frog and dog. Seed is antifungal. Stem bark is astringent, antileucorrhoeic, antibilious and uterine sedative. Flower is uterine tonic, antidiabetic and antisyphilitic. Stem bark and flower is antibilious (Husain et al, 1992).... ashoka

Aconitum Heterophyllum

Wall. ex Royle.

Family: Ranunculaceae.

Family: Ranunculaceae.

Habitat: The alpine Himalayas from Sikkim to Garhwal and Assam.

English: Indian Aconite, Wolfsbane, Monkshood.

Ayurvedic: Vatsanaabha, Visha, Amrita, Vajraanga, Sthaavaravisha, Vatsanaagaka, Shrangikavisha, Garala.

Unani: Bish, Bishnaag.

Siddha/Tamil: Vasanaavi, Karunaab- hi.

Folk: Bacchanaag, Bish, Mithaa Zahar, Telia Visha.

Action: Narcotic, sedative, antilepro- tic, anti-inflammatory. Extremely poisonous. (Roots possess depressant activity, but after mitigation in cow's milk for 2-3 days, they exhibit stimulant activity.)

Key application: In neuralgia. (Aconitum napellus L. has been listed by German Commission E among unapproved herbs.)

The root contains diterpenoid alkaloids, which act as a powerful poison that affects the heart and central nervous system. Aconitine has a shortlived cardiotonic action followed by

Habitat: Cultivated at Manali and Rahla in Himachal Pradesh. Also found in northwestern Himalayas at altitudes ranging from 2,000 to 4,000 m.

English: Atis Root, Aconite.

Ayurvedic: Ativishaa, Arunaa, Vishaa, Shuklakandaa, Bhanguraa, Ghunapriyaa, Ghunavallabhaa, Kaashmiraa, Shishubhaishajyaa (indicating its use in paediatrics), Vishwaa.

Unani: Atees.

Siddha/Tamil: Athividayam.

Folk: Patis.

Action: Often regarded as non- poisosnous, antiperiodic, anti- inflammatory, astringent (used in cough, diarrhoea, dyspepsia), tonic (used after fevers), febrifuge, antispasmodic (used in irritability of stomach and abdominal pains).

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of the dried, tuberous root in emesis and helminthi- asis.

The roots yield 0.79% of total alkaloids, of which atisin is 0.4%. Atisine is much less toxic than aconitine and pseudoaconitine. (The inert character of the plant is well known to the hill people, who often use it as a vegetable.) The plant possesses potent immuno- stimulant properties.

Dosage: Root—0.6-2.08 g. (API Vol. I.)... aconitum heterophyllum

Annona Squamosa

Linn.

Family: Annonaceae.

Habitat: A native to South America and the West Indies; now cultivated throughout India.

English: Custard Apple, Sugar Apple, Sweet-sop.

Ayurvedic: Gandagaatra, Sitaa phala (also equated with Curcurbita maxima).

Unani: Sharifaa.

Siddha/Tamil: Sitaaphalam, Atta.

Action: Leaves—insecticide (seed powder, mixed with leaf juice is used for removing lice from scalp). Seeds—abortifacient. Root— purgative, used in blood dysentery.

Fruit—invigorating, sedative to heart, antibilious, antiemetic, expectorant. Dried, powdered unripe fruits—used for treating ulcers. Ripe fruit made into paste with betel leaves is applied to tumour to hasten suppuration. Leaves, bark, unripe fruit—strongly astringent; used for diarrhoea and dysentery.

A fraction of total alkaloid from roots exhibits antihypertensive, antispasmodic, antihistaminic and bron- chodilatory properties. Leaves contain a cardiotonic alkaloid, quinoline. Squamone and bullatacinone were selectively cytotoxic to human breast carcinoma.

In Cuban medicine, leaves are taken to reduce uric acid levels.... annona squamosa

Asclepias Curassavica

Linn.

Family: Aristolochiaceae.

Habitat: Indigenous to the northern parts of southern Europe, Central and East-Central Europe; cultivated in the United States. A related sp., Asarum himalaicum, synonym A. canadense, is reported from the eastern Himalayas.

English: Asarbacca, Hazelwort, Wild Nard.

Unani: Asaaroon, Subul-e-Barri, Naardeen-Barri.

Folk: Tagar Ganthodaa.

Action: Brain and nervine tonic, diuretic, deobstructant and anti- inflammatory; used in bronchial spasm and in preparations of cephalic snuffs.

The volatile oil (0.7-4%) consists of asarone up to 50%, asaraldehyde 2-3%, methyleugenol 15-20%, with bornyl acetate, terpenes and sesquiterpenes. Asarone and its beta-isomer is found to be carcinogenic in animals. The rhizome, in addition, contains caffeic acid derivatives and flavonoids.

A related sp., Asarum canadense L., indigenous to North America and China, contains a volatile oil (3.5-

Family: Asclepiadaceae.

Habitat: Naturalized in many parts of India as an ornamental.

English: Curassavian Swallow- Wort, West Indian Ipecacuanha, Blood-Flower.

Ayurvedic: Kaakanaasikaa (substitute).

Folk: Kaakatundi (Kashmir).

Action: Spasmogenic, cardiotonic, cytotoxic, antihaemorrhagic, styptic, antibacterial. Various plant parts, as also plant latex, are used against warts and cancer. Root—used as an astringent in piles. Leaves—juice, antidysenteric, also used against haemorrhages. Flowers—juice, styptic. Alcoholic extract of the plant—cardiotonic.

An alcoholic extract of the Indian plant has been reported to contain a number of cardenolides, including calactin, calotropin, calotropagenin, coroglaucigenin, uzarigenin, asclepin, its glucosides and uzarin. Asclepin, the chief active principle, is spasmogenic and a cardiac tonic, having longer duration of action than digoxin (96 h in cat, as opposed to the 72 h of digoxin). Calotropin exhibits cytotoxic activity.

Pleurisy root of the U.S. is equated with Asclepias tuberosa. It is used for cold, flu and bronchitis in Western herbal medicine.

Toxic principles of the herb include galitoxin and similar resins, and glu- cofrugoside (cardenolide). Toxicity is reduced by drying.... asclepias curassavica

Buchanania Lanzan

Spreng.

Synonym: B. latifolia Roxb.

Family: Anacardiaceae.

Habitat: Drier parts of India.

English: Almondette tree, Cheron- jee, Buchanan's Mango.

Ayurvedic: Priyaala, Piyaala, Kharskandha, Bahulvalkala, Taa- paseshtha, Sannakadru Dhanush- pat, Chaar.

Unani/Tamil ? Saaraapparuppu.

Siddha: Mudaima, Morala (Tamil).

Action: Kernel—laxative, febrifuge. An ointment made out of the kernels is used to cure itch of the skin and to remove blemishes from the face. Oil from kernels— substitute for almond oil. Applied to glandular swellings of the neck. The oil is a promising source of palmitic and oleic acids.

Kernel lipids (65.6%), comprised mainly of neutral lipids (90.4%), consist mostly of triacylglycerol (82.2%), free fatty acids (7.8%) and small amount of diacylglycerols, monoacylglycerols and sterols.

The kernels are used in Indian medicine as a brain tonic. The leaves are valued as a cardiotonic.

The leaves contain 2.64% tannins (0.35% gallo-tannins). The presence of triterpenoids, saponins, flavonoids and reducing sugars are also reported. Powdered or crushed leaves are applied to wounds.

The bark contains 13.40% tannins. The presence of alkaloids, saponins and reducing sugars is also reported.

Gum (stem exudate) is antidiar- rhoeal. Used internally in rheumatism.

Dosage: Stem bark—5-10 g (API Vol. IV.)... buchanania lanzan

Cucurbits

Cucurbitaceae

The family Cucurbitaceae includes a large group of plants which are medicinally valuable. The important genera belonging to the family are Trichosanthes, Lagenaria, Luffa, Benincasa, Momordica, Cucumis, Citrullus, Cucurbita, Bryonopsis and Corallocarpus. The medicinally valuable species of these genera are discussed below.

1. Trichosanthes dioica Roxb.

Eng: Wild Snake-gourd; San: Meki,Pargavi, Parvara, Patola;

Hin: Palval, Parvar

Ben: Potol;

Mal: Kattupatavalam, Patolam;

Tam: Kombuppudalai;

Tel: Kommupotta

Wild snake-gourd is a slender-stemmed, extensively climbing, more or less scabrous and woolly herb found throughout the plains of N. India, extending to Assam and W. Bengal. Tendrils are 2-4 fid. Leaves are 7.5x5cm in size, ovate-oblong, cordate, acute, sinuate- dentate, not lobed, rigid, rough on both surface and with a petiole of 2cm. Flowers are unisexual. Male flowers are not racemed but woolly outside. Calyx tube is 4.5cm long, narrow, teeth linear and erect. Anthers are free. Fruit is 5.9cm long, oblong or nearly spherical, acute, smooth and orange-red when ripe. Seeds are half-ellipsoid, compressed and corrugated on the margin (Kirtikar and Basu, 1988). The unripe fruit of this is generally used as a culinary vegetable and is considered very wholesome and specially suited for the convalescent. The tender shoots are given in decoction with sugar to assist digestion. The seeds are useful for disorders of the stomach. The leaf juice is rubbed over the chest in liver congestion and over the whole body in intermittent fevers (Nadkarni, 1998). The fruit is used as a remedy for spermatorrhoea. The fresh juice of the unripe fruit is often used as a cooling and laxative adjunct to some alterative medicines. In bilious fever, a decoction of patola leaves and coriander in equal parts is given. The fruit in combination with other drugs is prescribed in snakebite and scorpion sting (Kirtikar and Basu, 1988).

Fruits contain free amino acids and 5-hydroxy tryptamine. Fatty acids from seeds comprise elaeostearic, linoelic, oleic and saturated acids. The aerial part is hypoglycaemic. Leaf and root is febrifuge. Root is hydragogue, cathartic and tonic. Unripe leaf and fruit is laxative (Husain et al, 1992). The plant is alterative and tonic. Leaves are anthelmintic. Flower is tonic and aphrodisiac. The ripe fruit is sour to sweet, tonic, aphrodisiac, expectorant and removes blood impurities.

The other important species belonging to the genus Trichosanthes are as follows.

T. palmata Roxb. T. cordata Roxb. T. nervifolia Linn.

T. cucumerina Linn.

T. anguina Linn.

T. wallichiana Wight. syn. T. multiloba Clarke

2. Lagenaria vulgaris Ser. syn. Cucurbita Lagenaria Linn. ; Roxb.

Eng: Bottle gourd San: Alabu Hin: Lauki, Jangli-khaddu

Ben: Lau, Kodu

Mal: Katuchuram, Churakka

Tam: Soriai-kay

Tel: Surakkaya

Bottle gourd is a large softly pubescent climbing or trailing herb which is said to be indigenous in India, the Molucas and in Abyssinia. It has stout 5-angled stems with bifid tendrils. Leaves are ovate or orbiculate, cordate, dentate, 5-angular or 5-lobed, hairy on both surfaces. Flowers are large, white, solitary, unisexual or bisexual, the males long and females short peduncled. Ovary is oblong, softly pubescent with short style and many ovules. Fruits are large, usually bottle or dumb-bell-shaped, indehiscent and polymorphous. Seeds are many, white, horizontal, compressed, with a marginal groove and smooth. There are sweet fruited and bitter-fruited varieties (Kirtikar and Basu, 1988). The fruit contains a thick white pulp which, in the cultivated variety (kodu) is sweet and edible, while in the smaller wild variety (tamri) it is bitter and a powerful purgative. The seeds yield clear limpid oil which is cooling and is applied to relieve headache. The pulp of the cultivated forms is employed as and adjunct to purgatives and considered cool, diuretic and antibilious, useful in cough, and as an antidote to certain poisons. Externally it is applied as a poultice. The leaves are purgative and recommended to be taken in the form of decoction for jaundice (Nadkarni, 1998). In the case of sweet-fruited variety, the stem is laxative and sweet. The fruit is sweet oleagenous, cardiotonic, general tonic, aphrodisiac, laxative and cooling. In the case of bitter-fruited variety, the leaves are diuretic, antibilious; useful in leucorrhoea, vaginal and uterine complaints and earache. The fruit is bitter, hot, pungent, emetic, cooling, cardiotonic, antibilious; cures asthma, vata, bronchitis, inflammations ulcers and pains.

3. Luffa acutangula (Linn.) Roxb.

Eng: Ridged gourd; San: Dharmargavah, Svadukosataki;

Hin: Tori, Katitori;

Ben: Ghosha

Mal: Peechil, Peechinga;

Tam: Pikangai, Prikkangai;

Tel: Birakaya;

Kan: Kadupadagila

Ridged gourd or ribbed gourd is a large monoecious climber cultivated throughout India. It is with 5-angled glabrous stems and trifid tendrils. Leaves are orbicular-cordate, palmately 5-7 lobed, scabrous on both sides with prominent veins and veinlets. Flowers are yellow, males arranged in 12-20 flowered axillary racemes. Female flowers are solitary, arranged in the axils of the males. Ovary is strongly ribbed. Fruits are oblong-clavate with 10-sharp angles 15-30cm long, tapering towards the base. Seeds are black, ovoid-oblong, much compressed and not winged (Warrier et al, 1995). The leaves are used in haemorrhoids, leprosy, granular-conjunctivitis and ringworm. The seeds are useful in dermatopathy. The juice of the fresh leaves is dropped into the eyes of children in granular conjunctivitis, also to prevent the lids from adhering at night on account of excessive meihomian secretion (Nadkarni, 1998). Fruits are demulcent, diuretic, tonic, expectorant, laxative and nutritive. The seeds are bitter, emetic, cathartic, expectorant and purgative.

The other important species of the genus Luffa are:

L. aegyptiaca Mill.

L. acutangula var. amara Clarke

L. echinata Roxb.

4. Benincasa hispida (Thumb.) Cogn. syn. B. cerifera Savi.

Eng: Ash gourd, White gourd melon; San: Kusmandah;

Hin: Petha, Raksa;

Ben: Kumra

Mal: Kumpalam;

Tam: Pusanikkai;

Kan: Bile Kumbala;

Tel: Bodigummadi

Ash gourd or White gourd melon is a large trailing gourd climbing by means of tendrils which is widely cultivated in tropical Asia. Leaves are large and hispid beneath. Flowers are yellow, unisexual with male peduncle 7.5-10cm long and female peduncle shorter. Fruits are broadly cylindric, 30-45cm long, hairy throughout and ultimately covered with a waxy bloom. The fruits are useful in asthma, cough, diabetes, haemoptysis, hemorrhages from internal organs, epilepsy, fever and vitiated conditions of pitta. The seeds are useful in dry cough, fever, urethrorrhea, syphilis, hyperdipsia and vitiated conditions of pitta (Warrier et al,1993). It is a rejuvenative drug capable of improving intellect and physical strength. In Ayurveda, the fresh juice of the fruit is administered as a specific in haemoptysis and other haemorrhages from internal organs. The fruit is useful in insanity, epilepsy and other nervous diseases, burning sensation, diabetes, piles and dyspepsia. It is a good antidote for many kinds of vegetable, mercurial and alcoholic poisoning. It is also administered in cough, asthma or respiratory diseases, heart diseases and catarrah. Seeds are useful in expelling tapeworms and curing difficult urination and bladder stones. The important formulations using the drug are Kusmandarasayana, Himasagarataila, Dhatryadighrita, Vastyamantakaghrita, Mahaukusmandakaghrita, etc. (Sivarajan et al, 1994).

Fruits contain lupeol, -sitosterol, n-triacontanol, vitamin B, mannitol and amino acids. The fruit is alterative, laxative, diuretic, tonic, aphrodisiac and antiperiodic. Seed and oil from seed is anthelmintic (Husain et al, 1992).

5. Momordica charantia Linn.

Eng: Bitter gourd, Carilla fruit San: Karavellam

Hin: Karela, Kareli

Mal: Kaypa, Paval

Tam: Pavakkai, Paval, Pakar

Tel: Kakara

Bitter gourd or Carilla fruit is a branched climbing annual which is cultivated throughout India. It is a monoecious plant with angled and grooved stems and hairy or villous young parts. Tendrils are simple, slender and elongate. Leaves are simple, orbicular, cordate and deeply divided into 5-7 lobes. Flowers are unisexual, yellow and arranged on 5-10cm long peduncles. Fruits are 5-15cm long with 3-valved capsules, pendulous, fusiform, ribbed and beaked bearing numerous triangular tubercles. Seeds are many or few with shining sculptured surface. The roots are useful in coloptosis and ophthalmopathy. The leaves are useful in vitiated conditions of pita, helminthiasis, constipation, intermittent fever, burning sensation of the sole and nyctalopia. The fruits are useful in skin diseases, leprosy, ulcers, wounds, burning sensation, constipation, anorexia, flatulence, colic, helminthiasis, rheumatalgia, gout, diabetes, asthma, cough, dysmenorrhoea, impurity of breast milk, fever and debility. Seeds are useful in the treatment of ulcers, pharyngodynia, and obstructions of the liver and spleen. The leaves and fruits are used for external application in lumbago, ulceration and bone fractures and internally in leprosy, haemorrhoids and jaundice (Warrier et al, 1995). The drug improves digestion, calms down sexual urge, quells diseases due to pitta and kapha and cures anaemia, anorexia, leprosy, ulcers, jaundice, flatulence and piles. Fruit is useful in gout, rheumatism and complaints of liver and spleen (Nadkarni, 1954; Aiyer and Kolammal, 1966; Mooss, 1976; Kurup et al, 1979). Kaccoradi taila is an important preparation using the drug (Sivarajan et al, 1994).

The seeds give triterpene glycosides, named momordicosides A, B, C, D and E, which are glycosides of cucurbit-5-en-triol, tetraol or pentaol. Leaves and vines give tetracyclic triterpenes-momordicines I, II and III (bitter principles). Immature fruits give several non-bitter and 2 bitter cucurbitacin glycosides. Four of the non-bitter glycosides, momordicosides F1, F2, G and I and the bitter momordicosides; K and L have also been characterized. Fruits, seeds and tissue culture give a polypeptide which contained 17 types of amino acids and showed hypoglycaemic activity. Fruits also give 5-hydroxy tryptamine and a neutral compound charantin (a steroidal glucoside), diosgenin, cholesterol, lanosterol and -sitosterol. Leaf is emetic, purgative and antibilious. Fruit is stomachic, tonic, carminative, febrifuge, antirheumatic and hypoglycaemic. Root is astringent. Fruit and leaf is anti-leprotic. Fruit, leaf and root are abortifacient and anti-diabetic. Leaf and seed is anthelmintic. Seed oil possesses antifeeding and insecticidal properties. Unsaponifiable matter from seed oil exhibited pronounced inhibitory activity against gram negative bacteria. Seed and fruit are hypoglycaemic, cytotoxic and anti-feedant (Husain et al, 1992).

Other important species belonging to the genus Momordica are as follows.

M. dioica Roxb.

M. cochinchinensis Spreng.

M. tuberosa Cogn.

M. balsamina Linn.

6. Cucumis melo Linn. syn. C. melo Linn. var. cultis Kurz., C. pubescens

Willd., C. callosus (Rottl.) Cogn.

Eng: Sweet melon San,

Hin: Kharbuja

Ben: Kharmul

Mal: Mulam

Tam: Chukkari-kai, Thumatti-kai, Mulampazham

Tel: Kharbuja-doshavSweet melon is a creeping annual extensively cultivated throughout India, found wild in India, Baluchistan and tropical Africa. The stem is creeping, angular and scabrous. Leaves are orbicular-reniform in outline, 5-angled or lobed, scabrous on both surfaces and often with soft hairs. Lobes of leaves are not very deep nor acute and with 5cm long petiole. Female peduncle is 5cm. Fruit is spherical, ovoid, elongate or contorted, glabrous or somewhat hairy, not spinous nor tuberculate.

Cucumis melo includes two varieties, namely,

C. melo var. momordica syn. C. momordica Roxb.

C. melo var. utilissimus Duthie & Fuller. syn. C. utilissimus Roxb.

The fruit is eaten raw and cooked. Its pulp forms a nutritive, demulcent, diuretic and cooling drink. It is beneficial as a lotion in chronic and acute eczema as well as tan and freckles and internally in cases of dyspepsia. Pulp mixed with cumin seeds and sugar candy is a cool diet in hot season. Seeds yield sweet edible oil which is nutritive and diuretic, useful in painful discharge and suppression of urine. The whole fruit is useful in chronic eczema (Kirtikar & Basu, 1988).

Seeds contain fatty acids-myristic, palmitic, oleic, linoleic; asparagine, glutamine, citrulline, lysine, histidine, arginine, phenylalanine, valine, tyrosine, leucine, iso-leucine, methionine, proline, threonine, tryptophan and crystine. Seed is tonic, lachrymatory, diuretic and urease inhibitor. Fruit pulp is eczemic. Fruit is tonic, laxative, galactagogue, diuretic and diaphoretic. The rind is vulnerary (Husain et al, 1992).

7. Cucumic sativus Linn.

Eng: Cucumber, Common cucumber; San: Trapusah;

Hin,

Ben: Khira;

Mal: Vellari

Tam: Vellarikkai, Pippinkai;

Kan: Mullusavte;

Tel: Dosekaya

Cucumber is a climbing annual which is cultivated throughout India, found wild in the Himalayas from Kumaon to Sikkim. It is a hispidly hairy trailing or climbing annual. Leaves are simple, alternate, deeply cordate, 3-5 lobed with both surfaces hairy and denticulate margins. Flowers are yellow, males clustered, bearing cohering anthers, connective crusted or elevated above the cells. Females are solitary and thickly covered with very bulbous based hairs. Fruits are cylindrical pepo of varying sizes and forms. Seeds are cream or white with hard and smooth testa. The fruits are useful in vitiated conditions of pitta, hyperdipsia, burning sensation, thermoplegia, fever, insomnia, cephalgia, bronchitis, jaundice, haemorrhages, strangury and general debility. The seeds are useful in burning sensation, pitta, constipation, intermittent fevers, strangury, renal calculus, urodynia and general debility (Warrier et al, 1994). The leaves boiled and mixed with cumin seeds, roasted, powdered and administered in throat affections. Powdered and mixed with sugar, they are powerful diuretic (Nadkarni, 1998). The fruits and seeds are sweet, refrigerant, haemostatic, diuretic and tonic. Other important species belonging to the genus are:

C. trigonus Roxb. syn. C. pseudo-colocynthis

C. prophetarum Linn.

8. Citrullus colocynthis (Linn.) Schrader. syn. Cucumis colocynthis Linn.

Eng: Colocynth, Bitter apple; San: Visala, Mahendravaruni;

Hin: Badi indrayan, Makkal

Ben: Makhal;

Mal: Kattuvellari (Valutu), Valiya pekkummatti;

Tel: Etti-puchcha

Tam: Paitummatti, Petummatti;

Colocynth or Bitter apple is found, cultivated and wild, throughout India in warmer areas. It is an extensively trailing annual herb with bifid tendrils angular branching stems and wooly tender shoots. Leaves are deeply divided, lobes narrow thick, glabrous or somewhat hairy. Flowers are unisexual, yellow, both males and females solitary and with pale-yellow corolla. Fruit is a globose or oblong fleshy indehiscent berry, 5-7.5cm in diameter and variegated with green and white. Seeds are pale brown. The fruits are useful in tumours, ascites, leucoderma, ulcers, asthma, bronchitis, urethrorrhea, jaundice, dyspepsia, constipations, elephantiasis, tubercular glands of the neck and splenomegaly (Warrier et al, 1994). It is useful in abnormal presentations of the foetus and in atrophy of the foetus. In addition to the above properties, the root has a beneficial action in inflammation of the breasts, pain in the joints; externally it is used in ophthalmia and in uterine pains. The fruit and root, with or without is rubbed into a paste with water and applied to boils and pimples. In rheumatism, equal parts of the root and long pepper are given in pill. A paste of the root is applied to the enlarged abdomen of children (Kirtikar and Basu, 1988). The fruit is useful in ascites, biliousness, jaundice, cerebral congestion, colic, constipation dropsy, fever, worms and sciatica. Root is given in cases of abdominal enlargement, cough, asthma, inflammation of the breast, ulcers, urinary diseases and rheumatism. Oil from seeds is used for poisonous bites, bowel complaints, epilepsy and also for blackening the hair (Nadkarni, 1954; Dey, 1980). The important formulations using the root and fruit are Abhayarista, Mahatiktakam kasaya, Manasamitravatakam, Cavikasava, Madhuyastyadi taila, etc. (Sivarajan et al, 1994). The powder is often used as an insecticide. The extract should never be given without some aromatic to correct its griping tendency (Nadkarni, 1998).

Fruit contains a glycoside- colocynthin, its aglycone- -elaterin, citrulluin, citrullene and citrullic acid. Unripe fruit contains p-hydroxy benzyl methyl ester. Roots contain - elaterin and hentriacontane (Husain et al, 1992). Colocynth is, in moderate doses, drastic, hydrogogue, cathartic and diuretic. In large doses, it is emetic and gastro-intestinal irritant and in small doses, it is expectorant and alterative. Colocynthin is a cathartic and intensely bitter principle. It has a purgative action. All parts of the plant are very bitter. The fruit has been described as cathartic (Nadkarni, 1982).

9. Citrullus vulgaris Schrad. syn. C. lanatus (Thunb.) Mats. & Nakai.

Eng: Water melon; San: Tarambuja;

Hin: Tarbuj;

Ben: Tarbuz

Mal: Thannimathan;

Tam: Pitcha, Dharbusini

Watermelon is an extensively climbing annual which is largely cultivated throughout India and in all warm countries. It has thick angular branching stems. Tendrils are bifid, stout and pubescent. Leaves are long, deeply divided or moderately lobed, glabrous or somewhat hairy and hardly scabrous. Petiole is a little shorter than the limb and villous. Calyx-lobes are narrowly lanceolate, equalling the tube. Corolla is yellow within, greenish outside and villous. Lobes are ovate-oblong, obtuse and prominently 5-nerved. Fruit is sub-globose or ellipsoid, smooth, greenish or clouded, often with a glaucous waxy coating. Flesh is juicy, red or yellowish white. Seeds are usually margined. C. vulgaris var. fistulosus Duthie & Fuller. syn. C. fistulosus has its fruit about the size of small turnip, the seeds of which are used medicinally. The fruit is tasteless when unripe and sweet when ripe. The unripe fruit is used to cure jaundice. Ripe fruit cures kapha and vata and causes biliousness. It is good for sore eyes, scabies and itching. The seeds are tonic to the brain and used as a cooling medicine. An emulsion of the seeds is made into a poultice with the pounded leaves and applied hot in cases of intestinal inflammations (Kirtikar and Basu, 1988). Fruit juice is good in quenching thirst and it is used as an antiseptic in typhus fever with cumin and sugar. It is used as a cooling drink in strangury and affections of urinary organs such as gonorrhoea; in hepatic congestion and intestinal catarrh. The bitter watermelon of Sind is known as “Kirbut” and is used as a purgative.

Seeds yield a fixed oil and proteids; citrullin. Seeds are cooling, demulcent, diuretic, vermifuge and nutritive. Pulp is cooling and diuretic. Fruit-juice is cooling and refreshing (Nadkarni, 1982).

10. Curcurbita pepo Linn. syn. Pepo vulgaris et P. verrucosus Moench

Meth.

Eng: Pompion, Pumpkin, Vegetable Marrow; San: Karkaru, Kurkaru, Kushmandi

Hin,

Ben: Kadimah, Konda, Kumra, Safedkkadu;

Mal: Mathan, Matha

Tel: Budadegummadi, Pottigummadi

Pompion or Pumpkin is a climbing herb which is considered to be a native of America and cultivated in many parts of India. The stem and leaves are with a harsh prickly armature. Foliage is stiff, more or less rigid and erect. Leaves are with a broad triangular pointed outline and often with deep lobes. Corolla is mostly with erect or spreading (not drooping) pointed lobes, the tube narrowing towards the base. Peduncle is strongly 5-angled and little or much expanding near the fruit. The fruit is cooling and astringent to the bowels, increases appetite, cures leprosy, ‘kapha and vata’, thirst, fatigue and purifies the blood. The leaves are used to remove biliousness. Fruit is good for teeth, throat and eyes and allays thirst. Seeds cure sore chests, haemoptysis, bronchitis and fever. It is good for the kidney and brain. The leaves are used as an external application for burns. The seeds are considered anthelmintic. The seeds are largely used for flavouring certain preparations of Indian hemp, and the root for a nefarious purpose, viz., to make the preparation more potent. The seeds are taeniacide, diuretic and demulcent. The fruit is cooling, laxative and astringent. The leaves are digestible, haematinic and analgesic.

The other important species belonging to the genus Cucurbita is C. maxima Duchena, the seeds of which are a popular remedy for tape-worm and oil as a nervine tonic (Kirtikar & Basu, 1988).

11. Corallocarpus epigaeus Benth. ex Hook. f. syn. Bryonia epigaea Wight.

San: Katunahi;

Hin: Akasgaddah;

Mal: Kadamba, Kollankova

Tam: Akashagarudan, Gollankovai;

Tel: Murudonda, Nagadonda

Corallocarpus is a prostrate or climbing herb distributed in Punjab, Sind, Gujarat, Deccan, Karnataka and Sri Lanka. It is monoecious with large root which is turnip-shaped and slender stem which is grooved, zigzag and glabrous. Tendrils are simple, slender and glabrous. Leaves are sub-orbicular in outline, light green above and pale beneath, deeply cordate at the base, angled or more or less deeply 3-5 lobed. Petiole is long and glabrous. Male flowers are small and arranged at the tip of a straight stiff glabrous peduncle. Calyx is slightly hairy, long and rounded at the base. Corolla is long and greenish yellow. Female flowers are usually solitary with short, stout and glabrous peduncles. Fruit is stalked, long, ellipsoid or ovoid. Seeds are pyriform, turgid, brown and with a whitish corded margin. It is prescribed in later stages of dysentery and old veneral complaints. For external use in chronic rheumatism, it is made into a liniment with cumin seed, onion and castor oil. It is used in case of snakebite where it is administered internally and applied to the bitten part. The root is given in syphilitic rheumatism and later stages of dysentery. The plant is bitter, sweet, alexipharmic and emetic. The root is said to possess alterative and laxative properties (Kirtikar and Basu, 1988). Root contains a bitter principle like Breyonin (Chopra et al, 1980).

Agrotechnology: Cucurbits can be successfully grown during January-March and September- December. For the rainfed crop, sowing can also be started after the receipt of the first few showers.

Pits of 60cm diameter and 30-45cm depth are to be taken at the desired spacing. Well rotten FYM or vegetable mixture is to be mixed with topsoil in the pit and seeds are to be sown at 4-5/pit. Unhealthy plants are to be removed after 2 weeks and retained 2-3 plants/pit. FYM is to be applied at 20-25t/ha as basal dose along with half dose of N (35kg/ha) and full dose of P (25kg) and K (25kg). The remaining dose of N (35kg) can be applied in 2 equal split doses at fortnightly intervals. During the initial stages of growth, irrigation is to be given at an interval of 3-4 days and at alternate days during flowering and fruiting periods. For trailing cucumber, pumpkin and melon, dried twigs are to be spread on the ground. Bitter gourd, bottle gourd, snake gourd and ash gourd are to be trailed on Pandals. Weeding and raking of the soil are to be conducted at the time of fertilizer application. Earthing up may be done during rainy season. The most dreaded pest of cucurbits is fruit flies which can be controlled by using fruit traps, covering the fruits with polythene, cloth or paper bags, removal and destruction of affected fruits and lastly spraying with Carbaryl or Malathion 0. 2% suspension containing sugar or jaggery at 10g/l at fortnightly intervals after fruit set initiation. During rainy season, downy mildew and mosaic diseases are severe in cucurbits. The former can be checked by spraying Mancozeb 0.2%. The spread of mosaic can be checked by controlling the vectors using Dimethoate or Phosphamidon 0.05% and destruction of affected plants and collateral hosts. Harvesting to be done at least 10 days after insecticide or fungicide application (KAU,1996).... cucurbits

Fritillaria Imperialis

L.

Family: Liliaceae.

Habitat: Kashmir at 1,700-3,000 m.

English: Crown Imperial, Imperial Fritillary.

Action: Bulbs—emollient, diuretic, resolvent, spasmolytic, hypotensive, cardiotonic.... fritillaria imperialis

Solanums

Solanum spp.

Solanaceae

Solanums comprise a very important group of medicinal plants having multifarious uses.

These plants belong to the family Solanaceae and genus Solanum. A number of species are reported to be medicinal which are briefly described below.

1. S. anguivi Lam. syn. S. indicum auct. non Linn.

Eng: Poison berry; San: Brhati, Simhi;

Hin: Barhauta, Birhatta;

Mal: Puthirichunda, Cheruchunda;

Tam: Karimulli, Puthirichundai;

Kan: Ramagulla;

Tel: Cittimulaga, Tellamulaka It is found throughout the tropics, in plains and at low elevations. It is much branched, very prickly undershrub, 0.3-1.5m in height. Leaves are simple, large, ovate, subentire, sinuate or lobed. Flowers are blue in extra-axillary cymes having stellately hairy and prickly peduncles. Fruits are globose berries, reddish or dark yellow with smooth or minutely pitted seeds. Its roots are useful in vitiated conditions of vata and kapha, odontalgia, dyspepsia, flatulence, colic, verminosis, diarrhoea, pruritus, leprosy, skin diseases, strangury, cough, asthma, bronchitis, amenorrhoea, dysmenorrhoea, fever, cardiac disorders and vomiting. Roots bitter, acrid, astringent, thermogenic, anodyne, digestive, carminative, anthelmintic, stomachic, constipating, resolvent, demulcent, depurative, diuretic, expectorant, aphrodisiac, emmenagogue, febrifuge and cardiotonic.

2. S. dulcamara Linn.

Eng: Bittersweet, Bitter night shade; San: Kakmachi; Pun: Rubabarik It is found in tropical situations in India and Sikkim. The plant is rich in alkaloidal glycosides like solamarine, tomatidenol, solasodine and soladulcine. The berry and twig are alterative, antisyphilitic, diaphoretic, resolvent, narcotic, diuretic, antirheumatic and used in liver disorders and psoriasis.

3. S. erianthum D. Don, syn. S. verbascifolium auct. non Linn.

San: Vidari;

Hin: Asheta;

Mal: Malachunda;

Tam: Malaichundai, Anaisundaikkai

Pun: Kalamena;

Tel: Rasagadi

The plant is distributed over the tropical and subtropical zones of India. The plant contains alkaloids and steroidal sapogenins. Leaves and fruits contain solasodine, solasodiene, solafloridine, diosgenin, vespertilin and pregnenolone. The plant is CNS depressant, antiinflammatory and useful in burns.

4. S. melongena Linn.

Eng: Brinjal, Egg plant; San: Varttaki;

Hin: Bengan, Badanjan;

Mal: Vazhuthina

Tam: Kattirikkai;

Kan: Badanekaya, Doddabadane;

Tel: Vankaya, Niruvanga

It is mainly cultivated as a vegetable throughout the tropics and subtropics. It is an erect or suffrutescent, herbaceous, armed or unarmed perennial shrub. Leaves are simple, large, entire and lobed. Flowers are blue, in clusters of 2-5. Fruits are large, white, yellow or dark purple berries of different shapes capped with thick persistent calyx. Seeds are many, yellow or cream and discoid. The roots, leaves and unripe fruits are useful in cholera, bronchitis, asthma, odontalgia and fever. The roots are laxative, analgesic and cardiotonic. Leaves are sialagogue, narcotic and antiherpetic. The unripe fruits are bitter, acrid, sweet, aphrodisiac, cardiotonic and haematinic.

5. S. melongena var. incanum (Linn.) Prain syn. S. incanum Linn., S. coagulens Forsk.

San: Brihati;

Hin: Baigan;

Mal: Cheruvazhuthina

It is a herbaceous prickly plant found in warm humid tropics. It is grown almost throughout the year in the plains and during summer on the hills. It grows 0.6-2m in height. Leaves are simple, alternate lobed. Flowers are blue or white, 5 lobed, calyx with spines. Fruits are ellipsoid berries. The plant is a constituent of the dasamoola which helps to overcome vitiated tridoshas and cures dyspepsia, fever, respiratory and cardiac disorders, skin ailments, vomiting, ulcers and poisonous affections. In Ayurveda the formulations like Brihatyadi Kashaya, dashamoolarishta, Indukantaghritam, Dasamoolaharithaki, etc are the important preparations with the roots. It is also used in the treatment of toothache and sore throat. The fruit is reported to stimulate the intrahepatic metabolism of cholesterol. Roots are antiasthmatic and stimulant. Leaves are used in cholera, bronchitis and asthma. Fruits are useful in liver complaints.

6. S. nigrum Linn. syn. S. rubrum Mill.

Eng: Black night shade; San: Kakamachi;

Hin: Makoy, Gurkkamai;

Mal: Karimthakkali;

Tam: Manathakkali, Milagutakkali;

Kan: Kakarndi;

Tel: Kamachi, Kachi

It is seen wild throughout India. It is an erect, divaricately branched, unarmed, suffrutescent annual herb. Leaves are ovate or oblong, sinuate-toothed or lobed and glabrous. Flowers are 3-8 in extra-axillary drooping subumbellate cymes. Fruits are purplish black or reddish berries. Seeds are many, discoid, yellow, minutely pitted. The whole plant is useful in vitiated conditions of tridosha, rheumatalgia, swellings, cough, asthma, bronchitis, wounds, ulcers, flatulence, dyspepsia, strangury, hepatomegaly, otalgia, hiccough, opthalmopathy, vomiting, cardiopathy, leprosy, skin diseases, fever, splenomegaly, haemarrhoids, nephropathy, dropsy and general debility. The plant is bitter, acrid, emollient, antiseptic, antiinflammatory, expectorant, anodyne, vulnerary, digestive, laxative, diuretic, cardiotonic, depurative, diaphoretic, febrifuge, rejuvenating, sedative, alterant and tonic.

7. S. spirale Roxb.

Hin: Munguskajur

It is seen wild in Assam and Khasi hills in India. Its root is diuretic and narcotic.

8. S. stramoniifolium Jacq., syn. S. ferox auct. non Linn.

San: Garbhada;

Hin: Rambaigan;

Mal: Anachunda;

Tam: Anaichundai;

Tel: Mulaka

It is observed in India in the states of Assam, Maharashtra, Karnataka and Tamil Nadu. Its berries contain glycoalkaloids such as solasonine and solasodine. Its roots and berries are bechic, antiasthmatic, antirheumatic, antiviral, anticancerous and spermicidal.

9. S. surattense Burm. F. syn. S. xanthocarpum schrad. & Wendl., S. jacquinii Willd.

Eng: Yellow-berried nightshade; San: Kantakari, Nidigdhika;

Hin: Remgani,Kateli;

Mal: Kantakarichunda;

Tam: Kantankattiri;

Kan: Nelagulli;

Tel: Callamulaga

It is found throughout India and Pakistan in dry situations as weed on roadsides and wastelands. It is prickly, diffuse, bright green, suffrutescent, perennial undershrub, with zigzag branches. Leaves are ovate-oblong, hairy on both sides and armed on the midrib and the nerves. Flowers are bluish purple, in extra-axillary cymes. Fruits are glabrous, globular drooping berry, yellow or white with green veins, surrounded by the calyx. Seeds are many, small, reniform, smooth and yellowish brown.

The whole plant is useful in vitiated conditions of vata and kapha, helminthiasis, dental caries, inflammations, flatulence, constipation, dyspepsia, anorexia, leprosy, skin diseases, hypertension, fever, cough, asthma, bronchitis, hiccough, lumbago, haemorrhoids and epilepsy. The plant is bitter, acrid, thermogenic, anthelmintic, antiinflammatory, anodyne, digestive, carminative, appetiser, stomachic, depurative, sudorific, febrifuge, expectorant, laxative, stimulant, diuretic, rejuvenating, emmenagogue and aphrodisac. Fruits contain solasonine, solamargine and solasodine.

10. S. torvum Sw.

Eng: West Indian Turkey Berry;

Hin,

Ben: Titbaigan;

Mal: Kattuchunda;

Kan: Kadu Sunde;

Tam: Sundaikai, Amarakai;

Tel: Kundavustic, Kotuvestu; Ass: Hathibhekuri

It is seen throughout tropical India, particularly in Orissa, Bihar and Manipur. The plant is CVS active and used in splenomegaly. Fruits and leaves contain solasonine, solasodine, jurubine, jurubidine, torvonin, torvogenin, chlorogenin, paniculogenin, sisalogenone, neosolaspigenin and solaspigenin.

11. S. trilobatum Linn.

Eng: Climbing Brinjal; San: Alarka;

Mal: Tutavalam;

Tam: Tuduvalai;

Kan: Mullumusta;

Tel: Telavuste

It is mostly seen in South and Western India. The plant contains alkamine and solamarine. The berry and flowers are bechic and used in bronchitis. The alkaloid solamarine is antibiotic and possesses antitumour activity.

12. S. viarum Dunal, syn. S. Khasianum C. B. Clarke

Hin: Kantakari

It is widely distributed in Khasi, Jaintia and Naga hills of Assam and Manipur upto 2000m and in Sikkim, West Bengal, Orissa and in the Niligiris. The plant and berries contain solasonine (which on hydrolysis yields solasodine), solamargine, khasianine, nantigenin, solasodine, diosgenin and saponin-solakhasianin. The plant is spasmolytic and CNS active. The berry is a source of solasodine used in the synthesis of corticosteroidal hormones.

Agrotechnology: The agrotechnology for the solanaceous group of plants are almost similar. They come up very well in tropical and subtropical climate upto 2000m altitude. They can be raised on a variety of soils good in organic matter. Propagation is by seeds. The seedlings are first raised in the nursery and transplanted to the main field 30-45 days after sowing when the plants attain 8-10cm height. During rainy season, planting is done on ridges while during summer in furrows, at a spacing ranging from 30-90cm depending upon the stature and spreading habit of the plant. The transplanted seedlings should be given temporary shade for 2-4 days during summer. FYM or compost at 20-25t/ha is applied at the time of land preparation. A moderate fertiliser dose of 75:40:40 N, P2O5, K2O/ha may be given. P is given as basal dose, N and K are applied in 2-3 split doses. One or two intercultural operations are needed to control weeds. The plants need earthing up after weeding and topdressing. Irrigation is needed at 3-4 days interval during summer and on alternate days during fruiting period. Plants need staking to avoid lodging due to heavy bearing. Shoot borers, mealy bugs, leaf webbers and miners are noted on the crop, which can be controlled by spraying mild insecticides. Root knot nematode, wilting and mosaic diseases are also noted on the crop. Field sanitation, crop rotation and burning of crop residues are recommended.... solanums

Terminalia

Terminalia spp.

Combretaceae

The genus Terminalia includes a large group of medicinally valuable trees. They belong to the family Combretaceae.

The most important medicinal species of the genus Terminalia are the following.

1) T. arjuna (Roxb.ex DC) Wight & Arn.

San: Arjunah, Kakubhah;

Hin: Arjun, Kahu, Kahua;

Mal: Marutu, Nirmarutu, Venmarutu, Attumarutu, Pulamatti;

Tam: Attumarutu, Nirmarutu, Vellaimarutu, Marutu;

Kan: Maddi.

It is a large evergreen tree commonly found in Madhya Pradesh, Bihar and Peninsular and India. It has buttressed trunk and spreading crown with drooping branches. Bark is smooth, grey outside and flesh coloured inside, flaking off in large flat pieces. Leaves are simple, sub-opposite, oblong or elliptic, coriaceous, crenulate, pale dull green above, pale brown beneath, often unequal sided, nerves 10-15 pairs and reticulate. Flowers are white, arranged in panicles of spikes with linear bracteoles. Fruits are ovoid or oblong with 5-7 short, hard angles or wings, the lines on the wings oblique and curving upward (Warrier et al 1996).

The bark is useful in fractures, ulcers, urethrorrhoea, leucorrhoea, diabetes, vitiated conditions of pitta, anaemia, cardiopathy, fatigue, asthma, bronchitis, tumours, internal and external haemorrhages, cirrhosis of the lever and hypertension. It is used in fractures and the powdered bark is taken with milk. The bark powder is diuretic and has a general tonic effect in cases of cirrhosis of liver. The bark has been considered by the ayurvedic physicians as well as by modern practitioners as a cardiac tonic. It is given as a decoction with milk (NRF, 1998). In Ayurveda, “Arjunaghrita” and “Arjunarishta” are two important cardiotonic preparations of this drug.

Fruits contain flavanones - arjunone and 5,7,2’, 4’ - tetramethoxy flavone and a chalcone - cerasidin. Other constituents are -sitosterol, friedelin, methyloleanolate, gallic acid, ellagic acid and arjunic acid. Bark gave a triterpene arjungenin, triterpene glucosides I, II and III. Stem bark gave flavones - baicalein and arjunolone characterised as 6,4’ - dihydraxy - 7-methoxy flavone. Stem bark yields oxalic acid and tannins besides complex glycosides (Bhatra et al, 1980). Bark is alexertic, styptic, antidysenteric, astringent, antiasthmatic, febrifuge, expectorant, cardiotonic aphrodisiac and diuretic. Fruit is deobstruent. Stem-bark is CVS and CNS active, diuretic and abortifacient. Aerial part is CNS depressant and semen coagulant.

2) T. alata Heyne ex Roth. Syn. T. tomentosa (Roxb. Ex. Dc.) W & A.

San: Dharaphala, Saradru, Sajada;

Hin. Ain;

Ben: Asan, Paishal;

Mal: Tehmbara;

Tam: Karramarda, Karu Murutha, Marudam, Pudavam.

This tree is distributed in Himalaya from Kangra eastwords to Goalpara in Assam and southwards throughout the Peninsular India, upto 1200 m. The bark of the tree is widely used in ulcers, fractures, bronchitis and diarrhoea. Hydrolysis of the gum gives oligosaccharides, disaccharides and monosaccharides. Leaves and fruits give -sitosterol. Bark is diuretic, antihaemorrhagic, styptic, cardiotonic and semen coagulant.

3) T. bellirica (Craertn.) Roxb.

San: Aksha, Anilaghanaka, Baheduka, Harya, Kalinda;

Hin: Bulla, Sagona;

Ben: Bahera, Baheri;

Tam: Akkam, Kalanduri, Tani;

Tel: Bhutavasamu Tadi, Tandra, Vibhutakamu.

Belliric Myrobalan is distributed throughout India, upto 900 m. Its bark is used in anaemia and leucoderma. The fruit is used in bronchitis, strangury, sore throat, diseases of eye, nose, heart and bladder, hoarseness and piles. It forms an important constituent of the ayurvedic drug ‘triphala’. Furits contain -sitosterol, gallic and ellagic acids, ethyl gallate, galloyl glucose, chebulagic acid and a cardiac glucoside bellaricanin. Alcoholic extract of the fruit possesses bile-stimulating activity. Alcoholic extract, 30 mg/kg does not affect blood pressure and respiration, but a higher dose of 60 mg/kg produces a fall in blood pressure. Furit has anticancerous and flower has spermicidal activity. Bark is mild diuretic. Fruit is astringent, antidropsical, antileprotic, antiinflammatory, antidiarrhoeal, antibilious, stomachic, antiasthmatic, tonic, anticephalgic, bechic, anthelmintic and attenuant. Kernel is narcotic. Semi -ripe fruit is purgative. Gum is demulcent (Husain et al, 1992)

4) T. bialata steud.

White Chugalam or silver grey wood is a common tree of Andaman Islands. Its bark is used as a cardiac stimulant.

5) T. Catappa Linn.

San: Grahadruma;

Hin: Badam;

Ben: Bangla Badam:

Tam: Natuvdom, Vadhamkottai;

Tel: Vedam, Voda Movettilla; Mar: Jangli Badama, Nat Badam.

Indian Almond or Tropical Almond is a popular tree cultivated throughout the warmer parts of India including Andaman Islands and other adjacent island. Oil from the kernel is a substitute for almond oil. The leaf is used in scabies and colic. Husk and endocarp contain tannins and pentosans. Oil from kernel contains oleic, linoleic, palmitic and stearic acids. Heart wood and stem bark contains -sitosterol and its palmitate. Heartwood in addition contains terminolic acid and triterpenic methyl esters. The aerial part of the plant is diuretic. The bark is astringent, mild diuretic, cardiotonic and antidysenteric. Leaf is sudorific, antirheumatic, antileprotic and anticephalalgic.

6) T. Coriacea (Roxb.) syn. T. tomentosa (Roxb. ex. DC.) W. & A. var. coriacea (Roxb.) C. B. Clarke

Tam: Anaimikkuvam, Sadagam;

Kan: Banapu;

Tel: Tani.

Leathery Murdah is a tree commonly used as a cardiac stimulant. It is widely distributed in the drier and warmer parts of Andhra Pradesh and Tamil Nadu upto 1350 m and in Central India. Its bark is mainly used as a cardiac stimulant and in atonic diarrhoea and callous ulcer. It is also CVS active.

7) T. myriocarpa Heurck. & Muell. Arg.

Ben: Panisaj; Ass: Hollock, Jhalna.

Hollock is a tree of the Himalayas widely distributed from Nepal to Arunachal Pradesh and in Assam at 1000 m. The bark is cardiac stimulant and mild diuretic. Bark give -sitosterol, fructose and 4,4’,5,5’,6,6’ - hexadydroxy diphenic acid dilactone. Bark also contains tannis - ellagic, gallic, chebulinic and chebulagic acids.

8) T. Pallida Brandis.

Tam: Vellai Kadukkay;

Tel: Tella Karaka, Velama Karka.

The plant is distributed throughout south India, upto 600m. Its bark is a mild diuretic.

9) T. Paniculata Roth.

Mal: Marutu, Pe Marutu, Ven Marutu;

Tam: Pei Kadukai, Ven Maruthu, Ilai Kadukkay, Marudu, Pullatti;

Tel: Nimiri, Pulamaddi, Putamanu, Pulanallamanu;

Kan: Maruva, Matti.

Flowering Murdah is a tree which is widely used in opium poisoning. It is distributed in the Western and Eastern Ghats, upto 1200m. The bark is used in parotitis and flowers in opium poisioning. Heart wood give 3, 3’-0-di-methylellagic acid and 3,4,3’0-trimethyl flavellagic acid, -sitosterol, an uncharacterized triterpene carboxylic acid; a glycoside -3,3’ di-0 - methyl ellagic acid - 4 - monoglucoside and 0 - penta methyl flavellogic acid. The stem bark is anticancerous, diuretic, cardiotonic CVS active and shows antagonism of amphetamine hyperactivity. Flower is anticholerin (Husain et al, 1992)

10) Terminalia chebula Retz. Syn. Myrobalanus chebula (Retz.) Gaertner

Eng: Chebulic myrobalan;

San,

Ben: Haritaki;

Hindi:Harara, Harir,

Har; Mal:Kadukka; Ass:Hilikha; Kan:Alale;

Mar:Habra,

Hirada;

Ori:Harida;

Guj: Hirdo;

Pun:Helela;

Tam:Amagola;

Tel: Karaka

Chebulic myrobalan is a medium deciduous tree, the fruit of which is a common constituent of “Triphala” capable of imparting youthful vitality and receptivity of mind and sense. It is a major constituent in the ayurvedic preparations like Abhayarishta, Abhaya modak, Haritaki khand, Triphaladi churnam and Agastya rasayanam. In allopathy it is used in astringent ointments. In unani system, it is used as a blood purifier. The pulp of the fruit is given in piles, chronic diarrhoea, dysentery, costiveness, flatulence, asthma, urinary disorders, vomiting, hiccup, intestinal worms, ascites and enlarged spleen and liver. Powder of the fruit is used in chronic ulcers and wounds, carious teeth and bleeding ulceration of the gums. The bark is a good cardiac tonic. The fruit is valuable for its tannins and dyes. The wood is used for building purposes, agricultural implements, plywood and match box industries. It is also grown as a shade tree.

The plant is found throughout India chiefly in deciduous forests, on dry slopes upto 900m especially in Bengal, Tamil Nadu, West coast and Western Ghats. The plant is also reported in Sri Lanka, Nepal and Burma.

Terminalia chebula Retz. syn. Myrobalanus chebula (Retz.) Gaertner comes under family Combretaceae. It is a medium sized deciduous tree with a cylindrical bole, rounded crown, spreading branches with dark brown bark and brownish gray heartwood. Leaves are simple, alternate or subopposite, ovate or elliptic ovate with short petioles bearing 2 glands below the blades. Flowers pale yellow or white in 4-10cm long axillary spikes. Calyx tube hairy pale yellow and 5 lobed; no petals. Stamens consist of 10 filaments subulate, anthers small; ovary inferior, 1-celled with 2-3 pendulous ovule. Fruit is a drupe, ovoid glossy, glabrous, faintly angled and yellow to orange brown in colour. Seeds are hard and pale yellow.

Kernel oil of Chebulic myrobalan contains 6 fatty acids viz. Palmitic, stearic, oleic, linoleic, arachidic and behenic acid. The fruits contain chebulinic acid, tannic acid, gallic acid, chebulin and tannin. Leaves contain terpenes and saponins and -sitosterol is present in the bark (Beri, 1970; Khalique and Nizamuddin, 1972; Miglani and Chawla, 1974). Fruits are astringent, purgative, tonic, carminative, alternative and antispasmodic. Flowers and fruits are antiviral and hypoglycaemic. Wood is oxytocic and hypothermic (Husain et al, 1992).

Agrotechnology: Terminalia species are, in general, subtropical trees. Young plants prefer shade while the matured plants tolerate light frost and drought. It grows well in hilly areas. This is propagated by seeds. Natural multiplication happens rarely due to the poor seeds germination. Seeds soaked in water for 48 hours before sowing in seedbeds which should be covered with straw after sowing. It is watered immediately. Usually it takes 3-5 months to germinate. It can be transferred to polybags at two-leaf stage. One-year-old seedlings are ready for transplanting. For transplanting, pits are made of 50cm cube at a spacing of 4m. Organic manure, added regularly, promotes growth. Irrigation is required during first year. Weeds should be removed regularly. This plant grows slowly. It fruits within 6-7 years. This is continued for many years. It is coppiced well. Fruits are collected immediately after falling down or covered with soil to protect it from pests. Fruits dried well in sun and used or stored. The hard seed coat is removed before sowing.... terminalia

Terminalia Citrina

Roxb. ex Flem.

Family: Combretaceae.

Habitat: Foothills of Himalayas from Nepal eastwards to Assam.

Folk: Haritaki (Bengal); Monalu (Assam), Suravaari Harad (Gujarat).

Action: Bark—diuretic, cardiotonic. Fruits—used as those of T. chebula.

The tannin in the fruit is reported to be between 30-40% of the dry weight.... terminalia citrina

Bael

Aegle marmelos

Rutaceae

San: Bilva, Sriphal Hin, Ben, Ass: Bael Mal: Koovalam

Tam: Vilvam Mar,

Ben: Baela

Tel: Marendu, Bilvapondu

Guj: Bilviphal

Kan: Bilvapatra

Importance: Bael or Bengal quince is a deciduous sacred tree, associated with Gods having useful medicinal properties, especially as a cooling agent. This tree is popular in ‘Shiva’ and ‘Vishnu’ temples and it can be grown in every house. Its leaves are trifoliate symbolizing the ‘Thrimurthies’-Brahma, Vishnu, Shiva, with spear shaped leaflets resembling “Thrisoolam” the weapon of Lord Shiva. Many legends, stories and myths are associated with this tree. The leaflets are given to devotees as ‘prasadam’ in Shiva temples and as ‘Tulasi’ in Vishnu temples.

Every part of the tree is medicinal and useful. The roots are used in many Ayurvedic medicines for curing diabetes and leprosy. It is an ingredient of the ‘dasamoola’. The Bark is used to cure intestinal disorders. Leaves contain an alkaloid rutacin which is hypoglycaemic.

‘Two leaves before breakfast’ is said to keep diabetes under control. Leaves and fruits are useful in controlling diarrhoea and dysentery. Fruit pulp is used as ‘shampoo’ and cooling agent. It is also a rich source of carbohydrate, protein, fat, fibre, minerals and vitamin B and C. Fruit pulp is used to cure mouth ulcers as it is the richest natural source of riboflavin (1191 units/ 100 g). ‘Bael sharbat’ is prepared by mixing the fruit pulp with sugar, water and tamarind juice, which is very useful for stomach and intestinal disorders. The rind of the fruit is used for dyeing and tanning. The aromatic wood is used to make pestles in oil and sugar mills and also to make agricultural implements (Rajarajan, 1997).

Distribution: Bael tree is native to India and is found growing wild in Sub-Himalayan tracts from Jhelum eastwards to West Bengal, in central and south India. It is grown all over the country, especially in the premises of temples and houses.

Botany: Aegle marmelos (Linn.) Corr.ex Roxb. belongs to the citrus family Rutaceae. The golden coloured bael fruit resembles a golden apple and hence the generic name Aegle. The specific name marmelos is derived from marmelosin contained in the fruit (Nair, 1997). Aegle marmelos is a medium sized armed deciduous tree growing upto 8m in height with straight sharp axillary thorns and yellowish brown shallowly furrowed corky bark. Leaves are alternate, trifoliate and aromatic; leaflets ovate or ovate-lanceolate, crenate, pellucid- punctate, the laterals subsessile and the terminal long petioled. Flowers are greenish-white, sweet scented, borne on axillary panicles. Fruit is globose, woody berry with golden yellow rind when ripe. Seeds are numerous oblong, compressed and embedded in the orange brown sweet gummy pulp.

Agrotechnology: Bael comes up well in humid tropical and subtropical climate. It grows on a wide range of soils from sandy loam to clay loam. North Indian varieties are preferred to South Indian types for large scale cultivation. Twelve varieties are cultivated in North India for their fruits. Kacha, Ettawa, Seven Large, Mirsapuri and Deo Reo Large are varieties meant specially for ‘Sharbat’. The plant is propagated mainly by seeds and rarely by root cuttings. Seeds are freshly extracted from ripe fruits after removing the pulp and then dried in sun. Seeds are soaked in water for 6 hours and sown on seed beds which are covered with rotten straw and irrigated regularly. Seeds germinate within 15-20 days. One month old seedlings can be transplanted into polybags which can be planted in the field after 2 months. Budded or grafted plants as well as new saplings arising from injured roots can also be used for planting. Grafted plants start yielding from the 4th year while the trees raised from seeds bear fruits after 7-10 years. Planting is done in the main field with onset of monsoon in June-July at a spacing of 6-8m. Pits of size 50cm3 are dug. Pits are filled with a mixture of top soil and 10kg of well decomposed FYM and formed into a heap. Seedlings are transplanted in the middle of the heap and mulched. Chemical fertilisers are not usually applied. The dose of organic manure is increased every year till 50kg/tree of 5 years or more. Regular irrigation and weeding are required during early stages of growth. No serious pests and diseases are noted in the crop. Bael tree flowers during April. The flowers are aromatic with pleasant and heavenly odour. The fruits are set and slowly develop into mature fruits. Fruits are seen from October-March. A single tree bears 200-400 fruits each weighing 1-2 kg. Roots can be collected from mature trees of age 10 years or more. Tree is cut down about 1m from the ground. The underground roots are carefully dug out. Roots with the attached wood is then marketed (Rajarajan,1997).

Properties and activity: Bael is reported to contain a number of coumarins, alkaloids, sterols and essential oils. Roots and fruits contain coumarins such as scoparone, scopoletin, umbelliferone, marmesin and skimmin. Fruits, in addition, contain xanthotoxol, imperatorin and alloimperatorin and alkaloids like aegeline and marmeline identified as N-2-hydroxy-2- 4 - (3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide. - sitosterol and its glycoside are also present in the fruits. Roots and stem barks contain a coumarin - aegelinol. Roots also contain psoralen, xanthotoxin, 6,7-dimethoxy coumarin, tembamide, mermin and skimmianine. Leaves contain the alkaloids - O-(3,3-dimethyl allyl)-halfordinol, N-2-ethoxy-2 (4-methoxy phenyl) ethyl cinnamide, N-2-methoxy-2-(4-3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N- 2-4-(3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N-2-hydroxy-2- 4-(3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N-4-methoxy steryl cinnamide and N-2-hydroxy-2-(4- hydroxy phenyl) ethyl cinnamide. Mermesinin, rutin and -sitosterol - -D-glucoside are also present in the leaves (Husain et al, 1992).

Root, bark, leaves and fruits are hypoglycaemic, astringent and febrifuge. Root, stem and bark are antidiarrhoeal and antivenin. Leaf is antiinflammatory, expectorant, anticatarrhal, antiasthamatic, antiulcerous and ophthalmic. Flower is emetic. Unripe fruit is stomachic and demulcent. Ripe fruit is antigonorrhoeal, cardiotonic, restorative, laxative, antitubercular, antidysenteric and antiscorbutic. Seed is anthelmintic and antimicrobial (Warrier et al, 1993).... bael

Brahmi

Bacopa monnieri

Scrophulariaceae

San: Brahmi, Sarasvati;

Hin: Barami, Jalnim;

Ben: Boihim-sak;

Mal: Brahmi , Nirbrahmi;

Tam: Nirpirami, Piramiyapundu; Kan, Mar: Nirbrahmi

Importance: Brahmi or Thyme leaved gratiola is an important drug in Ayurveda for the improvement of intelligence and memory and revitalisation of sense organs. It clears voice and improves digestion. It is suggested against dermatosis, anaemia, diabetes, cough, dropsy, fever, arthritis, anorexia, dyspepsia, emaciation, and insanity. It dispels poisonous affections, splenic disorders and impurity of blood. It is useful in vitiated conditions of kapha and vata, biliousness, neuralgia, ascites, flatulence, leprosy, leucoderma, syphilis, sterility and general debility. The whole plant is used in a variety of preparations like Brahmighrtam, Sarasvataristam., Brahmitailam, Misrakasneham, etc. In unani Majun Brahmi is considered as a brain tonic.

Distribution: The plant grows wild on damp places and marshy lands in the major part of the plains of India, Pakistan, Afghanistan, Nepal, Sri Lanka and other tropical countries.

Botany: Bacopa monnieri (Linn.) Pennell. syn. Monniera cuneifolia Michx., Herpestis monniera (Linn.) H.B. & K. belongs to the family Scrophulariaceae. It is a prostrate, juicy, succulent, glabrous annual herb rooting at the nodes with numerous ascending branches. Leaves are simple, opposite, decussate, sessile, obovate-oblong or spatulate, entire, fleshy, obscurely veined and punctate. Flowers are pale blue or whitish, axillary, solitary, arranged on long slender pedicels. Fruits are ovoid, acute, 2-celled, 2-valved capsules and tipped with style base. Seeds are minute and numerous (Warrier et al, 1993).

Agrotechnology: The plant grows throughout the warm humid tropics upto 1200m elevation. Brahmi gets established well in water logged fields. The plant is propagated vegetatively by stem cuttings. Land is prepared by ploughing 2 or 3 times. Two to three tonnes/ha of cowdung or compost is applied and the field is again ploughed and levelled. Stem cuttings, 10cm long are spread at a spacing of 20cm. Waterlogging to height of 30cm is always required. Rooting may start within 15-20 days. It will spread over the field within 6 months. Regular application of organic manure will take care of the manurial requirement. Weeding once in a month is required. Care should be taken to maintain water level at a height of 30cm during the growth period. No serious pests or diseases are noted in this crop. Harvesting commences from sixth months onwards. Brahmi leaves can be collected once a month. After 3 years, the whole crop is harvested and removed. Fresh cultivation can be carried out in the same field.

Properties and activity: Earlier workers have reported the isolation of the alkaloids brahmine and hespestine and a mixture of 3 alkaloids from the leaves. Mannitol and saponins were reported later. Subsequent work described isolation of some C27, C29, and C31 hydrocarbons and betulic acid from this plant material. A systematic examination has resulted in the isolation and identification of two saponins designated as bacosides A and B. Bacoside A has chemical structure represented as 3-(-L-arabinopyranosyl)-O- - D-glucopyranoside-10, 20-dihydroxy-16-ketodammar-24-ene. The mixture of bacosides A and B on hydrolysis give four sapogenins, glucose and arabinose. The constitution of bacogenin A, has been established as 3 -30-dihydroxy-20(5)-25-epoxy-22-methyl-24-nor-dammar-22-en-16-one. Bacogenin A2 has been shown to be an isomer of bacogenin A, differing in configuration at C-20. Bacogenin A4 has been identified as ebelin lactone.

The plant is reported to have shown barbiturate hypnosis potentiation effect. The plant is anticancerous and improves learning ability. It is used as a tranquilliser. The plant is astringent, bitter, sweet, cooling, laxative, intellect promoting, anodyne, carminative, digestive, antiinflammatory, anticonvulsant, depurative, cardiotonic, bronchodialator, diuretic, emmenagogue, sudorfic, febrifuge and tonic (Basu et al, 1947; Rastogi et al 1960).... brahmi

Carissa Carandas

Linn. var. congesta (Wt.) Bedd.

Family: Apocynaceae.

Habitat: Throughout India.

English: Christ's Thorn, Bengal Currant.

Ayurvedic: Karinkaara, Karamarda, Krishnapaakphal, Kshirphena, Sushena, (Karamardakaa is equated with C. spinarum Linn.)

Unani: Karondaa.

Siddha/Tamil: Kalakke.

Action: Used for acidity, flatulence, poor digestion, as a slimming diet. Juice of the fresh plant is used for infected wounds that refuse to heal. Root—paste used for diabetic ulcer.

The Ayurvedic Pharmacopoeia of India indicated the stem bark in obstinate skin diseases, and the root in urinary disorders.

Alcoholic extract of roots exhibit hypotensive activity. Roots yield car- dioactive compounds; cardiotonic activity is due to glucoside of odoroside H. Fresh fruits are rich in ascorbic acid (105 g/100 g fruit juice). The seeds are rich in potassium (360 mg/100 g fresh matter).

Dosage: Stem bark—48 g for decoction. (API Vol. II); root— 1-3 g (API Vol. III).... carissa carandas

Carissa Opaca

Stapf. Ex Haines.

Synonym: C. spinarum auct. non L.

Family: Apocynaceae.

Habitat: Throughout the country in dry regions, especially in Punjab and Kashmir.

Ayurvedic: Karamardikaa.

Siddha/Tamil: Chirukila Chiru.

Folk: Jangali Karondaa. Garnaa (Punjab).

Action: Plant—cardiotonic. Root— purgative.

The root contains caffeic acid, cardiac glycosides—odorosides B, C, G and H, and evomonoside.

Carissa paucinervia A. DC. is also equated with the wild var. ofKarondaa.... carissa opaca

Cereus Grandiflorus

Mill.

Family: Cactaceae.

Habitat: Indian gardens.

English: Cereus, Night Blooming Cereus, Sweet Scented Cactus.

Folk: Nivadung Paanchkoni (Maharashtra).

Action: Fresh, young shoots—cardiac stimulant, anti-inflammatory.

The plant contains glucose, fructose, starch, amino acids and citric, fumar- ic, maleic, malonic and oxalic acids. Tyramine, a cardiotonic amine, can strengthen heart muscle action.

The flower, stem and young shoots of cereus can stimulate heart and dilate peripheral vessels, as well as stimulate spinal cord motor neurons. The reputed digitalis effect of cereus is claimed to be non-cumulative. (Natural Medicines Comprehensive Database, 2007.)... cereus grandiflorus

Citrus Maxima

(Burm.) Merrill.

Synonym: C. decumana Watt. C. grandis (L.) Osbeck

Family: Rutaceae.

Habitat: North-eastern region up to 1,500 m in Assam and Tripura.

English: Pummelo, Shaddock.

Ayurvedic: Madhukarkatikaa.

Unani: Chakotra.

Siddha/Tamil: Pambalimasu.

Folk: Mahaa-nibu, Sadaaphal.

Action: Fruit—cardiotonic. Leaves, flowers and rind—used as a sedative in nervous affections. Leaves— used in convulsive cough, chorea, epilepsy, also in the treatment of haemorrhagic diseases. A lotion of boiled leaves used hot in painful swellings. The essential oil from fresh leaves exhibits dermatophytic, and fungistatic activity.

The root-bark contains beta-sitos- terol and acridone alkaloids. It also contains several coumarins. The alkaloids and coumarins show antimicrobial acitivity.

The essential oil from the leaves and unripe fruits contain 20% limonin, 30% nerolol, 40% nerolyl acetate and 3% geraniol. diosmin, beta-sitosterol and beta-D- glucoside. The roots contain campes- terol, stigmasterol, sitosterol and cholesterol.

Aqueous extract of the peel showed hypotensive action in dogs.

The fruits and seeds are a cardioton- ic; found useful in palpitation.

Dosage: Fruit—10-20 ml juice. (API Vol. III.) Leaf, flower, fruit, root— 50-100 ml decoction. (CCRAS.)... citrus maxima

Cocculus Hirsutus

(Linn.) Diels.

Synonym: C. villosus (Lam.) DC.

Family: Menispermaceae.

Habitat: Throughout tropical and sub-tropical tracts of India.

English: Broom-Creeper, Ink-Berry.

Ayurvedic: Chhilihinta, Paataala- garuda, Mahaamuulaa, Dirghavalli, Jalajamani.

Siddha/Tamil: Kattukodi.

Action: Root—laxative, sudorific, alterative, antirheumatic. Leaf— used externally for eczema, prurigo and inpetigo. A decoction of leaves is taken in eczema, leucorrhoea and gonorrhoea.

Aqueous extract of stem and root— sedative, anticonvulsant, hypotensive, bradycardiac, cardiotonic and sapas- molytic. Roots are used as a substitute for Sarsaparilla in chronic rheumatism gout, and syphilitic cachexia.

The stem contains cyclopeptide alkaloids. The plant contains coclaurine, magnoflorine, beta-sitosterol, ginnol and a monomethyl ether of inositol.

C.pendulus (Forsk.) Diels, synonym C. leaeba (Del.) DC. (Punjab, Gujarat and South India) is known as Parwati (Gujarat, Sindh) and Ullar-billar (Punjab).

Ethanolic extract of the leaves and stem showed anticancer and hypoten- sive activities associated with the al- kaloidal fraction which contains bis- benzylisoquinoline alkaloids (including pendulin and cocsulin). Presence of quercitol is reported from non- alkaloidal fraction.

Dosage: Root—50-100 ml decoction. (CCRAS.)... cocculus hirsutus

Cinchona

Cinchona spp.

Rubiaceae

San: Cinchona, Kunayanah

Hin: Kunain Mal: Cinchona, Quoina

Tam: Cinchona

Importance: Cinchona, known as Quinine, Peruvian or Crown bark tree is famous for the antimalarial drug ‘quinine’ obtained from the bark of the plant. The term cinchona is believed to be derived from the countess of cinchon who was cured of malaria by treating with the bark of the plant in 1638. Cinchona bark has been valued as a febrifuge by the Indians of south and central America for a long time. Over 35 alkaloids have been isolated from the plant; the most important among them being quinine, quinidine, cinchonine and cinchonidine. These alkaloids exist mainly as salts of quinic, quinovic and cinchotannic acids. The cultivated bark contains 7-10% total alkaloids of which about 70% is quinine. Similarly 60% of the total alkaloids of root bark is quinine. Quinine is isolated from the total alkaloids of the bark as quinine sulphate. Commercial preparations contain cinchonidine and dihydroquinine. They are useful for the treatment of malarial fever, pneumonia, influenza, cold, whooping couphs, septicaemia, typhoid, amoebic dysentery, pin worms, lumbago, sciatica, intercostal neuralgia, bronchial neuritis and internal hemorrhoids. They are also used as anesthetic and contraceptive. Besides, they are used in insecticide compositions for the preservation of fur, feathers, wool, felts and textiles. Over doses of these alkaloids may lead to deafness, blindness, weakness, paralysis and finally collapse, either comatose or deleterious. Quinidine sulphate is cardiac depressant and is used for curing arterial fibrillation.

Distribution: Cinchona is native to tropical South America. It is grown in Bolivia, Peru, Costa Rica, Ecuador, Columbia, Indonesia, Tanzania, Kenya, Zaire and Sri Lanka. It was introduced in 1808 in Guatemala,1860 in India, 1918 in Uganda, 1927 in Philippines and in 1942 in Costa Rica. Roy Markham introduced the plant to India. The first plantation was raised in Nilgiris and later on in Darjeeling of West Bengal. The value of the tree was learnt by Jessuit priests who introduced the bark to Europe. It first appeared in London pharmacopoeia in 1677 (Husain, 1993).

Botany: The quinine plant belongs to the family Rubiaceae and genus Cinchona which comprises over 40 species. Among these a dozen are medicinally important. The commonly cultivated species are C. calisaya Wedd., C. ledgeriana Moens, C. officinalis Linn., C. succirubra Pav. ex Kl., C. lancifolia and C. pubescens. Cinchona species have the chromosome number 2n=68. C. officinalis Linn. is most common in India. It is an evergreen tree reaching a height of 10-15m. Leaves are opposite, elliptical, ovate- lanceolate, entire and glabrous. Flowers are reddish-brown in short cymbiform, compound cymes, terminal and axillary; calyx tubular, 5-toothed, obconical, subtomentose, sub-campanulate, acute, triangular, dentate, hairy; corolla tube 5 lobed, densely silky with white depressed hairs, slightly pentagonal; stamens 5; style round, stigma submersed. Fruit is capsule ovoid-oblong; seeds elliptic, winged margin octraceous, crinulate-dentate (Biswas and Chopra, 1982).

Agrotechnology: The plant widely grows in tropical regions having an average minimum temperature of 14 C. Mountain slopes in the humid tropical areas with well distributed annual rainfall of 1500-1950mm are ideal for its cultivation. Well drained virgin and fertile forest soils with pH 4.5-6.5 are best suited for its growth. It does not tolerate waterlogging. Cinchona is propagated through seeds and vegetative means. Most of the commercial plantations are raised by seeds. Vegetative techniques such as grafting, budding and softwood cuttings are employed in countries like India, Sri Lanka, Java and Guatemala. Cinchona succirubra is commonly used as root stock in the case of grafting and budding. Hormonal treatment induces better rooting. Seedlings are first raised in nursery under shade. Raised seedbeds of convenient size are prepared, well decomposed compost or manure is applied , seeds are broadcasted uniformly at 2g/m2, covered with a thin layer of sand and irrigated. Seeds germinate in 10-20 days. Seedlings are transplanted into polythene bags after 3 months. These can be transplanted into the field after 1 year at 1-2m spacing. Trees are thinned after third year for extracting bark , leaving 50% of the trees at the end of the fifth year. The crop is damaged by a number of fungal diseases like damping of caused by Rhizoctoria solani, tip blight by Phytophthora parasatica, collar rot by Sclerotiun rolfsii, root rot by Phytophthora cinnamomi, Armillaria mellea and Pythium vexans. Field sanitation, seed treatment with organo mercurial fungicide, burning of infected plant parts and spraying 1% Bordeaux mixture are recommended for the control of the diseases (Crandall, 1954). Harvesting can be done in one or two phases. In one case, the complete tree is uprooted, after 8-10 years when the alkaloid yield is maximum. In another case, the tree is cut about 30cm from the ground for bark after 6-7 years so that fresh sprouts come up from the stem to yield a second crop which is harvested with the under ground roots after 6-7 years. Both the stem and root are cut into convenient pieces, bark is separated, dried in shade, graded, packed and traded. Bark yield is 9000-16000kg/ha (Husain, 1993).

Properties and activity: Over 35 alkaloids have been isolated from Cinchona bark, the most important among them are quinine, quinidine, cinchonine, cinchonidine, cinchophyllamine and idocinchophyllamine. There is considerable variation in alkaloid content ranging from 4% to 20%. However, 6-8% yield is obtained from commercial plantations. The non alkaloidal constituents present in the bark are bitter glycosides, -quinovin, cinchofulvic, cinchotannic and quinic acids, a bitter essential oil possessing the odour of the bark and a red coloring matter. The seed contains 6.13% fixed oil. Quinine and its derivatives are bitter, astringent, acrid, thermogenic, febrifuge, oxytocic, anodyne, anti-bacterial, anthelmintic, digestive, depurative, constipating, anti pyretic, cardiotonic, antiinflammatory, expectorant and calcifacient (Warrier et al, 1994; Bhakuni and Jain, 1995).... cinchona

Corchorus Aestuans

Linn.

Synonym: C. acutangulus Lam.

Family: Tiliaceae.

Habitat: Throughout the warmer parts of India, as a weed.

English: White Jute. (Tossa Jute is equated with C. olitorius Linn.).

Ayurvedic: Chunchu, Chanchu, Chinchaa. (bigger var. is equated with C. olitorius; smallar var. with C. capsularis.)

Folk: Chench shaaka, Titapat (Bengal).

Action: Seeds and aerial parts— stomachic, anti-inflammatory. Used in pneumonia.

The seeds contain cardenolides, beta-sitosterol, ceryl alcohol, oligosaccharides. The aerial parts contain triterpenoidal glycosides—corchoru- sins. Corchorusins have similar structural similarity with saikosaponins (isolated so far from Bupleurum sp. of Japan, China and Korea) and some of them exhibit antiviral, anti-inflam matory and plasma-cholesterol lowering activities.

The alcoholic extract of the entire plant was found to have anticancer activity against epidermal carcinoma of nasopharynx in tissue culture. Alcoholic extract and glycosides of seeds exhibit cardiotonic activity. Digitox- ose containing glycosides are reported to be present in Corchorus sp.

C. olitorius Linn. is known as Jew's Mallow (Pattaa Shaaka or Patuaa Shaa- ka).

Corchorosid A, reported from the plant, improved cardiac competence experimentally.

The leaf extracts may be used as moisturizers in skin cosmetics. The extracts consist of uronic acid containing muco-polysaccharide, Ca, K and P, among others, which act as effective moisturizers.... corchorus aestuans

Corchorus Capsularis

Linn.

Family: Tiliaceae.

Habitat: Throughout warmer parts of India; extensively cultivated in West Bengal.

English: White Jute.

Ayurvedic: Kaala shaaka.

Siddha/Tamil: Pirattai-keerai.

Folk: Naadi shaaka, Narichaa. Titapat (Bengal).

Action: Leaves—stomachic, carminative, diuretic, antidysenteric (dried leaves). Seeds—purgative.

Seeds contain cardiac glycosides. These include two monosides, helveti- coside and corchoroside A and two polar glycosides, erysimoside and olitori- side. Leaves contain beta-sitosterol- glucoside. Corchoroside A exhibited cardiotonic properties.

The aqueous/alcoholic extracts, containing polysaccharides, may be used in preparations of skin cosmetics or hair preparations for their moisturizing effect.... corchorus capsularis

Corydalis Tea

Corydalis tea was used for centuries in ancient Chinese medicine as a pain reliever. But this tea has also various other health benefits. More on Corydalis tea Native to the northern parts of China, Japan, Eastern Russia and Eastern Africa, Corydalis is a perennial plant that usually grows in shade along the edges of woodlands. It possesses pink flowers and finely-divided thin leaves and yellow tubers. It is closely related to the opium poppy family. Its medicinal properties largely lie in the roots or rhizomes. Corydalis is used either as a decoction, tincture, extract or tea for its analgesic, antispasmodic, antiseptic, sedative, tranquilizing, anti-cancer, hypotensive and cardiotonic qualities. It contains more than 20 potent alkaloids that include tetrahydropalmatine, dehydrocorydaline, protopine and cordalines. Though its effects are somewhat similar to that given by the opium poppy, corydalis tea is said to be non-addictive. Its taste can be bitter so you might want to drink it along with some sweeteners. Corydalis herb is typically mixed with other herbs by Chinese herbal practitioners. They use it in a variety of ways, for example with peony and licorice to fight spastic pain, or with pteropus and bulrush for treating abdominal and menstrual pain. Corydalis tea brew Corydalis tea can be made by placing a handful of the dried roots in a pot of boiling water and allowing it to steep for about 15 to 20 minutes. Then let it simmer for a further 5 minutes before drinking it. Alternatively, an infusion can be made using the powdered form of the roots. Simply immerse the powdered corydalis roots in newly-boiled water for about 5 to 7 minutes. Corydalis tea benefits Here are some of the health benefits of Corydalis tea. It lowers blood pressure, eases heart rate and reinforces the circulation system. Being a pain reliever, Corydalis tea can ease chest and abdominal pains, fight pain in the lumbar region and  help relieve menstrual cramps and dysmenorrhea. It can cure anxiety, restlessness, sleeplessness and edginess. Corydalis tea may help fight stomach ulcers as it may help decrease gastric secretions. Corydalis tea may be helpful in fighting cough and allergies. Corydalis tea side effects Corydalis tea has some precautions that should be considered before taking it. Corydalis tea should always be used under the supervision of a health care provider. The tea is not for the use of children, pregnant or nursing women, liver or kidney disease. People taking sleeping pills, depressants and alcohol should avoid it, as the effects of such a combination have not yet been fully established. Corydalis tea can be included in a healthy life style, but first consult with your physician and do not drink too much of it.... corydalis tea

Costus Speciosus

(Koenig) Sm.

Family: Zingiberaceae.

Habitat: Assam, North Bengal, Khasi and Jaintia Hills, sub Himalayan tracts of Uttar Pradesh and Himachal Pradesh and Western Ghats.

English: Canereed, Wild Ginger.

Ayurvedic: Kebuka, Kembuka.

Siddha/Tamil: Krrauvam, Malai Vasambu, Ven Kottam.

Folk: Kebu.

Action: Astringent, purgative, depurative, anti-inflammatory (used in gout, rheumatism; bronchitis, asthma, catarrhal fevers, dysuria), anthelmintic, antivermin, maggoticide, antifungal.

The rhizomes contain saponins— dioscin, gracillin and beta-sitosterol- beta-D-glucoside. The alkaloids show papaverine-like smooth-muscle-relaxant activity, cardiotonic activity like that of digitalis and antispasmodic,

CNS-depressant, diuretic and hydro- choleretic activities. Saponins show significant anti-inflammatory and an- tiarthritic activity.

The seeds also contain saponins and exhibit potent and sustained hypoten- sive and bradycardiac activities in dogs with low toxicity and without any haemolytic activity; also weak spasmolytic activity on isolated guinea-pig ileum.

All parts of the plant yield steroidal sapogenin, diogenin (quantity varies from 0.32 to 4%).

(Not to be confused with Kushtha of Indian medicine, Saussurea lappa.)... costus speciosus

Desmodium

Desmodium gangeticum

Fabaceae

San: Anshumati, Salaparni;

Hin,

Ben: Salpani;

Mal: Orila;

Tam:Pulladi;

Tel: Gitanaram

Kan: Murelehonne; Mar: Darh;

Guj: Salwan; Ori: Salaparni Pun: Shalpurhi

Importance: Desmodium is a small shrub which is the chief of the ten ingredients in the Dasamula kwatha of Hindu medicine. Roots are useful in vitiated conditions of vata, anorexia, dyspepsia, haemorrhoids, dysentery, strangury, fever, gout, inflammations, cough, asthma, bronchitis, cardiopathy and debility. The unani preparation “Arq dashmul” contains these roots. It is considered a curative for leucorrhoea and for pains due to cold (Warrier et al, 1995).

Distribution: The plant is widely distributed in the tropics and subtropics. It grows wild in the forests of India up to 1500m. It is also cultivated in the plains and in the lower Himalayas.

Botany: Desmodium gangeticum (Linn.) DC. syn. Hedysarum gangeticum Linn., Desmodium gangeticum var. maculatum (Linn.) Baker., belongs to the family Fabaceae (Papilionaceae). It is an erect diffusely branched undershrub, 90-120cm in height with a short woody stem and numerous prostrate branches provided with soft grey hairs. Leaves are unifoliate, ovate- lanceolate, membranceous and mottled with grey patches. Flowers are white, purple or lilac in elongate lax, terminal or axillary racemes. Fruits are moniliform, 6-8 jointed, glabrescent pods, joints of pods separately pubescent with hooked hairs, joint separating when ripe into indehiscent one seeded segments. Seeds are compressed and reniform.

Agrotechnology: Desmodium can grow in a variety of climate and soils. However, it prefers tropical and subtropical climatic conditions. Although it can grow on all types of soils, waterlogged and highly alkaline soils are not suitable. Light sandy loam is preferred for commercial cultivation.

It is propagated through seeds. Seeds can be planted directly in the field or seedlings raised on the nursery beds and transplanted. Transplanting always gives better results in commercial cultivation, as it gives assured crop stand. Planting is done at a spacing of 40x20cm on flat beds or ridges. Organic manures are applied at the time of land preparation and thoroughly mixed with the soil. A little quantity of phosphatic and nitrogenous fertilizers are also applied for better crop growth. The inter-row spaces between plants, both in the field and nursery should be kept free from weeds by frequent weeding and hoeing as the plant suffers from weed competition, especially during early stages of growth. Manual hand weeding is usually done. Irrigation of seedlings just after planting is good for crop establishment. Although it can be cultivated as a rainfed crop under humid tropical conditions, irrigation every month is beneficial during summer. The root is the economic part and harvesting can be commenced after 8-9 months. About 500- 700kg roots can be harvested from a hectare of land per year.

Properties and activity: The root contains gangetin, gangetinin, desmodin, N,N-dimethyl tryptamine, hypaphorine, hordenine, candicine, N-methyl tyramine and -phenyl ethyl amine. The total alkaloid fraction showed hypotensive activity. The root is bitter, antiinflammatory, analgesic, aphrodisiac, constipating, diuretic, cardiotonic, expectorant, astringent, antidiarrhoeal, carminative, antiemetic, febrifuge and anti-catarrhal (Thakur et al, 1989).... desmodium

Fenugreek

Trigonella foenum-graecum

Fabaceae

San: Methika, Methi, Kalanusari;

Hin: Meti, Mutti; Ben, Mar: Methi;

Mal: Uluva;

Tam: Ventayam;

Kan: Mentya, Menlesoppu;

Tel: Mentulu, Mentikura; Arab: Hulabaha

Importance: Fenugreek or Greek Hayes is cultivated as a leafy vegetable, condiment and as medicinal plant. The leaves are refrigerant and aperient and are given internally for vitiated conditions of pitta. A poultice of the leaves is applied for swellings and burns. Seeds are used for fever, vomiting, anorexia, cough, bronchitis and colonitis. In the famous Malayalam treatises like ‘Padhyam’ ‘Kairali’ and ‘Arunodhayam’, uluva is recommended for use as kalanusari in Dhanvantaram formulations of ‘Astaghradayam’. An infusion of the seeds is a good cool drink for small pox patients. Powdered seeds find application in veterinary medicine. An aqueous extract of the seeds possesses antibacterial property (Kumar et al, 1997; Warrier et al, 1995).

Distribution: Fenugreek is a native of South Eastern Europe and West Asia. In India fenugreek is grown in about 0.30 lakh ha producing annually about 30,000 tonnes of seeds. The major states growing fenugreek are Rajasthan, Madhya Pradesh, Gujarat, Uttar Pradesh, Maharashtra, Punjab and Karnataka. It is grown wild in Kashmir and Punjab.

Botany: Trigonella foenum-graecum Linn. belongs to family, Fabaceae. It is an annual herb, 30-60cm in height, leaves are light green, pinnately trifoliate, leaflets toothed, flowers are white or yellowish white, papilionaceous and axillary. Fruits are legumes, 5-7.5cm long, narrow, curved, tapering with a slender point and containing 10-20 deeply furrowed seeds per pod. There are two species of the genus Trigonella which are of economic importance viz. T. foenum graecum, the common methi and T. corniculata, the Kasuri methi. These two differ in their growth habit and yield. The latter one is a slow growing type and remains in rosette condition during most of the vegetative growth period (Kumar et al, 1997; Warrier et al, 1995).

Agrotechnology: Fenugreek has a wide adaptability and is successfully cultivated both in the tropics as well as temperate regions. It is tolerant to frost and freezing weather. It does well in places receiving moderate or low rainfall areas but not in heavy rainfall area. It can be grown on a wide variety of soils but clayey loam is relatively better. The optimum soil pH should be 6-7 for its better growth and development. Some of the improved cultivars available for cultivation are CO1 (TNAU), Rajendra Kanti (RAU), RMt-1(RAU) and Lam Selection-1 (APAU). Land is prepared by ploughing thrice and beds of uniform size are prepared. Broadcasting the seed on the bed and raking the surface to cover the seeds is normally followed. But to facilitate intercultural operations, line sowing is also advocated in rows at 20-25cm apart. Sowing in the plains is generally in September-November while in the hills it is from March. The seed rate is 20-25kg/ha and the seeds germinate within 6-8 days. Besides 15t of FYM, a fertiliser dose of 25:25:50kg NPK/ha is recommended. Entire P,K and half N are to be applied basally and the remaining half N 30 days after sowing. First irrigation is to be given immediately after sowing and subsequent irrigations at 7-10 days interval. Hoeing and weeding are to be done during the early stages of plant growth and thinning at 25-30 days to have a spacing of 10-15cm between plants and to retain 1-2 plants per hill. Root rot (caused by Rhizoctonia solani) is a serious disease and can be controlled by drenching carbendazim 0.05% first at the onset of the disease and another after one monthof first application. In about 25-30 days, young shoots are nipped off 5cm above ground level and subsequent cuttings of leaves may be taken after 15 days. It is advisable to take 1-2 cuttings before the crop is allowed for flowering and fruiting when pods are dried, the plants are pulled out, dried in the sun and seeds are threshed by beating with stick or by rubbing with hands. Seeds are winnowed, cleaned and dried in the sun. They may be stored in gunny bags lined with paper. An yield of 1200-1500kg of seeds and about 800-1000kg of leaves may be obtained per hectare in crops grown for both the purposes (Kumar et al, 1997).

Properties and activity: Seeds contain sapogenins-diosgenin, its 25-epimer(yamogenin), tigogenin, gitogenin, yuccagenin, 25-2-spirosta-3-5-diene and its -epimer. Seeds also contain a C27-steroidal sapogenin-peptide ester-fenugreekine. Seeds, in addition, contain 4-hydroxyleucine and saponins-fenugrins A-E:two furostanol glycoxides-trigonelloxide C and (255)-22-O-methyl-52-firostan-3 ,22,26,triol-3-O- -rhamnopyrans syl(1-2) C- -D-glucopyranosyl (1-3)- -D- glucopyranoxide-26-O- -D-glucopyranoxide.

Other chemical constituents are sterols- -sitosterol and cholesterol, flavone C- glycosides-vitexin, iso-vitexin, vitexin-2”-O-P-coumarate and vicenin-2. Flavonoids- quercetin and luteolin, flavonoid glycoside-vicenin-I. Invitro seedling callus culture gave flavonoids-luteolin and vitexin-1-glycoside. An essential oil is also reported from seeds. Leaves gave saponins-gracecunins A-G, flavonoids- kaempferol and quercetin; sterols- - sitosterol, sapogenins-diosgenin, gitogenin coumarin-scopoletin is also reported from the plant.

Seeds are bitter, mucilaginous, aromatic, carminative, tonic, diuretic, thermogenic, galactagogue, astringent, emollient, amophrodisiac, antirheumatic, CNS depressant and antiimplantation. Fenugreekine is hypoglycaemic, diuretic, hypotensive, cardiotonic, antiphlogistic. It showed 80% inhibition of vaccina virus.... fenugreek

Ficus Cordifolia

Roxb.

Synonym: F. rumphii Bl.

Family: Moraceae.

Habitat: Throughout India, up to 1,700 m in the hills.

Ayurvedic: Ashmantaka (var.)

Folk: Gajanaa, Ashtaa, Paakar.

Action: Fruit juice and latex— antiasthmatic and vermifuge.

Siddha/Tamil: Kal Aal, Pei Aal.

Action: Fruit—cardiotonic. Leaves and bark—used in affections of the liver and skin diseases.... ficus cordifolia

Garcinia Pedunculata

Roxb.

Family: Guttiferae; Clusiaceae.

Habitat: Forests of northeast Bengal, sporadic in NEFA, Manipur and upper Assam

Ayurvedic: Amlavetasa. Vetasaamla.

Folk: Thaikala (Bengal).

Action: Antiscorbutic, astringent, cooling, cardiotonic, emollient. Used in anorexia, dyspepsia, colic, liver and spleen diseases difficult micturition. Cough and other respiratory disorders, ulcers and skin diseases.

Dry fruits (pericarp) contain the benzophenones, pedunculol, garcinol and cambogin.

The heartwood gave benzophenone and xanthone.

Dosage: Fruit—5-10 ml juice. (CCRAS.)... garcinia pedunculata

Gymnema

Gymnema sylvestre

Asclepiadaceae

San: Mesasrngi, Madhunasini;

Hin: Gudmar, Merasimgi;

Ben: Merasingi;

Mal: Chakkarakolli, Madhunasini;

Tam: Sirukurumkay, Sakkaraikkolli;

Kan: Kadhasige;

Tel: Podapatra; Mar: Kavali

Importance: Gymnema, Australian Cowplant, Small Indian Ipecacuanha or Periploca of the woods is a woody climber. It is reported to cure cough, dyspnoea, ulcers, pitta, kapha and pain in the eyes. The plant is useful in inflammations, hepatosplenomegaly, dyspepsia, constipation, jaundice, haemorrhoids, strangury, renal and vesical calculi, helminthiasis, cardiopathy, cough, asthma, bronchitis, intermittent fever, amenorrhoea, conjuctivitis and leucoderma. The fresh leaves when chewed have the remarkable property of paralysing the sense of taste for sweet and bitter substance for some time (Warrier et al, 1995). The drug is described as a destroyer of madhumeha (glycosuria) and other urinary disorders. Root has long been reputed as a remedy for snakebite. Leaves triturated and mixed with castor oil are applied to swollen glands and enlargement of internal viscera as the liver and spleen (Nadkarni, 1954). The drug is used to strengthen the function of heart, cure jaundice, piles, urinary calculi, difficult micturition and intermittent fevers (Sharma,1983). The drug enters into the composition of preparations like Ayaskrti, Varunadi kasaya, Varunadighrtam, Mahakalyanakaghrtam, etc. They suppress the activity of taste of tongue for sweet taste and for this reason it was considered that it destroys sugar, hence the name Madhunashini or Gurmar and has been prescribed as an anti-diabetic. The crude drug as well as its dried aqueous extract is mainly used in bronchial troubles.

Distribution: It is a tropical climber. It mainly grows in Western Ghats, Konkan, Tamil Nadu and some parts of Bihar. The plant is cultivated in plains of India but the drug is mainly important from Afghanistan and Iran.

Botany: Gymnema sylvestre (Retz.)R. Br. syn. Asclepias germinata Roxb. belonging to the family Asclepiadaceae is a large, woody much branched climber with pubescent young parts. Leaves are simple, opposite, elliptic or ovate, more or less pubescent on both sides, base rounded or cordate. Flowers are small, yellow and arranged in umbellate cymes. Fruits are slender and follicles are upto 7.5cm long (Warrier et al, 1995).

Two allied species, G. hirsutum found in Bundelkh and Bihar and Western Ghats and G. montanum growing wild in Eastern Ghats and Konkan are also used for the same purpose and are also called “Gurmar” (Thakur et al, 1989).

Agrotechnology: The plant can be propagated both by seeds and stem cuttings. Seedlings are to be raised in polybags. Pits of size 50cm cube are to be taken, filled with 10kg dried cowdung or FYM and covered with topsoil. On these pits about 3-4 months old seedlings are to be transplanted from polybags. Trailing can be facilitated by erecting poles and tying the plants to the poles. The plant will attain good spread within one year. Regular weeding, irrigation and organic manure application are beneficial. The plant is not attacked by any serious pests or diseases. Leaves can be collected from the first year onwards at an internal of one week. This can be continued for 10-12 years. Fresh or dried leaves can be marketed (Prasad et al, 1997).

Properties and activity: Nonacosane and hentriacontane were isolated from the hexane extract of leaves. An attempt to isolate nitrogenous compounds led to the isolation of amino acids such as leucine, iso-leucine, valine, allanine and - amynobutyric acid. Isolation of trimethyl amine oxide was of particular interest. An alkaloid gynamine which is a trace constituent was isolated and identified (Sinsheimer et al, 1967). Antisweet constituent of the leaves has been found to be a mixture of triterpene saponins. These have been designated as gymnemic acids A,B,C and D which have the gymnemagenin and gymnestrogenins as the aglycones of gymnemic acid A and B and gymnemic acid C and D respectively. These are hexahydroxy triterpenes the latter being partially acylated. The sugar residues are glucuronic acid and galacturonic acid while ferulic and angelic acids have been attached as the carboxylic acid.

Chewing of leaves reduces sensitivity to sweet substances. Effects of gymnema extracts had been variable. While verifying the effect of G. sylvestre leaves on detoxification of snake venom, it has been reported that a toxic component of venom ATP and gymnemate bind at the same site inhibiting venom ATP-ase. The active principles which have been identified as glycosides (7 gymnemic acids) suggest that the topical and selective anaesthetic effect of the plant might result from the competition of the receptor sites between glycosides and the sweet substances (Warren et al, 1969). The leaves are antidiabetic and insulinotropic. Gymnemic acid is antiviral. The plant is bitter, astringent, acrid, thermogenic, antiinflammatory, anodyne, digestive, liver tonic, emetic, diuretic, stomachic, stimulant, anthelmintic, alexipharmic, laxative, cardiotonic, expectorant, antipyretic and uterine tonic.... gymnema

Piper Betle

Linn.

Family: Piperaceae.

Habitat: Cultivated in warmer and damper parts of India; Assam, West Bengal, Bihar, Uttar Pradesh, Karnataka, Kerala.

English: Betel pepper.

Ayurvedic: Taambula, Naagvallari, Naagini, Taambulvalli, Saptashiraa, Bhujangalataa.

Unani: Paan, Tambool.

Siddha/Tamil: Vetrilai Nagavalli, Kammaaruvetritai.

Action: Leaf—stimulant, carminative, astringent, antiseptic. Essential oil from leaves—antispasmodic, antiseptic. Used in respiratory catarrhs. Fruit—bechic.

The leaves afforded beta- and gam- ma-sitosterol, hentriacontane, pen- tatriacontane, n-triacontanol, stearic acid and chavicol. The essential oil from leaves contained carvacrol, euge- nol, chavicol, allyl catechol, cineole, estragol, caryophyllene, cardinene, p- cymene and eugenol methyl ether.

Administration of the leaf extract resulted in decreased tumour burden and tumour incidence and a delay in the onset of mammary tumour in Wistar rats.

The alcoholic extract of the leaf stalk is reported to show antispermatogenic and antiandrogenic effect in male albino rats.

The essential oil exhibited hypoten- sive, cardiac as well as respiratory depressant and cardiotonic properties.

The leaf showed antifungal and antibacterial activity. The antiseptic activity is attributed to chavicol.

Dosage: Leaf—10-15 ml juice. (API, Vol. III.)... piper betle

Rhus Succedanea

Linn.

Synonym: R. acuminata DC.

Family: Anacardiaceae.

Habitat: The temperate Himalayas, from Kashmir, Sikkim to Bhutan at altitudes of 600-2,500 m.

English: Japanese Wax tree, Wild Varnish tree.

Ayurvedic: Karkatashringee. (Used as a substitute for Pistacia integerrima galls.).

Unani: Kaakraasingi.

Siddha/Tamil: Karkatakasringi, Kadukapoo (galls).

Action: Thorn-like excrescences on the branches—astringent, expectorant; prescribed in diarrhoea, dysentery and vomiting. Fruits— expectorant (used as an adjuvant in tuberculosis).

The sapwood and heartwood contain polyphenols. The sapwood contains gallo tannin; the heartwood gave fisetin, and its -7-glucoside, fustin, gar- banzol, 3,7,4'-trihydroxyflavone, gallic and ellagic acid. The bark is reported to contain 10% of tannin.

The juice from the leaves causes blisters. Leaves contain 20% tannin (dry basis), a flavone glycoside rhoifolin, co- rilagin and shikimic acid. Ethanolic extract of the leaves is reported to exhibit anticancer and antiviral activities. Latex from the stem also causes blisters.

Mesocarp of the fruit contains el- lagic acid. An acid isolated from the fruit is reported to be cardiotonic and sympathomimetic. It was found to be toxic to rabbits. However, the fruits are used in the treatment of tuberculosis. Hinokiflavone, isolated from the fruits, showed cytotoxic activity in vitro against KB culture cells.

Drupes are rich in biflavones.

The wax obtained from the pulpy mesocarp of the fruit contains palmitic 77, stearic 5, dibasic 6, oleic 12%, and linoleic acid (a trace). It is used as a substitute for beeswax.... rhus succedanea

Scilla Indica

Baker non-Roxb.

Synonym: S. hyacinthiana (Roth) Macb.

Ledebouria hyacinthina Roth.

Family: Liliaceae.

Habitat: Central and Southern India, including Deccan Peninsula.

English: South Indian Squill. Substitute for White Squill, Urginea maritima Baker and Indian Squill, Urginea indica Kunth.

Ayurvedic: Vana-Palaandu (South India), Korikanda.

Unani: Jangli Piyaz.

Siddha/Tamil: Kattu velvengayam.

Action: Bulb—cardiotonic, stimulant, expectorant, diuretic. Used in cough, dysuria, strangury. (Not used as a diuretic when kidneys are inflamed.)

The bulb contains cardioactive gly- cosides including bufadienolides, scil- laren A, scillaridin A and proscillari- din A.

The squill has shown to have cardiac effects similar to digoxin, including positive inotropic and negative chronotropic effects. The aglycones in squill are poorly absorbed from the GI tract and are therefore less potent than digitalis cardiac glycosides. Additional cardiovascular properties include reducing left ventricular dias- tolic pressure and reducing pathologically elevated venous pressure. (Natural Medicines Comprehensive Database, 2007.)

Large amounts of squill are gastric irritants; small amounts expectorant.

The squill of the Indian bazaars consists partly of S. indica and chiefly of Urginea indica.... scilla indica

Siegesbeckia Orientalis

Linn.

Family: Compositae; Asteraceae.

Habitat: Throughout India up to 2,000 m.

English: The Holy Herb, Siegesbeckia.

Siddha/Tamil: Katampam, Kadambu.

Folk: Pili-badkadi (Gujarat), Lat- latiaa (Bihar), Lichkuraa (Garhwal).

Action: Plant—antiscorbutic, sial- agogue, cardiotonic, diaphoretic. Used for the treatment of rheumatism, renal colic and ague. Also used as a lotion for gangrenous ulcers and sores, syphilis, leprosy, ringworm.

The aerial parts contain sesquiter- pene lactone, orientin; melampolides including orientolide; diterpene, dru- tigenol and the corresponding gluco- side darutoside. The whole plant, in addition, gave 3,7-dimethylquercetin.

The plant exhibited antiviral, CVS active, spasmolytic and hypoglycaemic activity.... siegesbeckia orientalis

Stephania Hernandiifolia

Walp.

Synonym: S. japonica Miers. S. sotunda Hook. f. & Thorns.

Family: Menispermaceae.

Habitat: Forests of the Western and Eastern Ghats.

Ayurvedic: Used as Raaj-Paathaa in the South. (Raaj-Paathaa is also equated with Cyclea arnotii Miers in southern and eastern parts of India).

Action: Root—prescribed in skin diseases, pruritus, inflamed piles, internal abscesses, urinary diseases, vomiting, diarrhoea, colic, respiratory disorders and as a cardiotonic.

The plant is rich in alkaloids. Aerial parts gave epi-stephanine (aknadine), hernandifoline, aknadinine and mag- noflorine. Alkaloid aknadine shows significant antispasmodic activity on uterine spasms. Cytotoxic alkaloids include d-and dl-tetrandrine, d-iso- chondrodendrine and fangchinoline. The alkaloid, epi-stephanine (akna- dine) possesses adrenergic neuron blocking activity.... stephania hernandiifolia

Tecomella Undulata

(G. Don) Seem.

Synonym: Tecoma undulata G. Don.

Bignonia undulata Sm.

Family: Bignoniaceae.

Habitat: North-West and Western India, and in the outer Himalayas.

English: Rohida tree.

Ayurvedic: Rohitaka, Rohi, Daadimpushpaka, Daadimchhada, Plihaghna. (Amoora rohituka is also known as Rohitaka.)

Action: Bark—relaxant, cardiotonic, choleretic. (Heartwood toxic due to lapachol.) Used for the treatment of leucorrhoea, diseases of the liver and spleen, leucoderma, syphilis and other skin diseases.

The bark contains tecomin (veratryl beta-D-glucoside), alkanes, alkanols and beta-sitosterols. The bark also yielded chromone glycosides—undu- latosides A and B, and iridoid glu- cosides—tecomelloside and tecoside.

A quinonoid—lapachol, veratric acid and dehydrotectol are also reported from the bark.

Water soluble portion of the alcoholic as well as chloroform extracts of the bark shows smooth muscle relaxant, mild cardiotonic and chloretic activities.

Dosage: Flower, bark—50-100 ml decoction. (CCRAS.)... tecomella undulata

Terminalia Arjuna

(Roxb.) W. & A.

Family: Combretaceae.

Habitat: Throughout the greater part of India, also grown as an avenue tree.

English: Arjun Terminalia.

Ayurvedic: Arjuna, Dhananjaya, Kaakubha, Kakubha, Aartagala, Indravriksha, Paartha, Virataru, Viravriksha.

Unani: Arjun

Siddha: Marudam.

Action: Bark—used as a cardiopro- tective and cardiotonic in angina and poor coronary circulation; as a diuretic in cirrhosis of liver and for symptomatic relief in hypertension; externally in skin diseases, herpes and leukoderma. Powdered bark is prescribed with milk in fractures and contusions with excessive ec- chymosis, also in urinary discharges and strangury. Fruit—deobstruent.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the powder of the stembark in emaciation, chest diseases, cardiac disorders, lipid imbalances and polyuria.

The bark extract contains acids (ar- junolic acid, terminic acid), glyco- sides (arjunetin, arjunosides I-IV), and strong antioxidants—flavones, tannins, oligomeric proanthocyani- dins.

The bark extract (500 mg every 8 h) given to (58 male) patients with stable angina with provocable ischemia on treadmill exercise, led to improvement in clinical and treadmill exercise parameters as compared to placebo therapy.

These benefits were similar to those observed with isosorbide mononitrate (40 mg/day). (Indian Heart J. 2002, 54(4), 441.)

Arjunolic acid exhibited significant cardiac protection in isoproterenol- induced myocardial necrosis in rats.

T (Mol Cell Biochem, 2001, 224 (1-2), 135-42.) A study demonstrated that the alcoholic extract of Terminalia arjuna bark augmented endogenous antioxi- dant compounds of the rat heart and prevented from isoproterenol-induced myocardial ischemic reperfusion injury. (Life Sci. 2003, 73 (21), 27272739.) Cardiac lipid peroxidation in male Wistar rats was reduced by 38.8% ± 2.6% at a dose of 90 mg/kg, in a study based on aqueous freeze-dried extract ofthebark. (PhytotherRes. 2001,15(6), 510-23.)

Oral administration of bark powder (400 mg/kg body weight) for 10 days produced significant increase in circulating histamine, a little increase in 5-HT, catecholamines and HDL cholesterol, and decrease in total lipid, triglycerides and total cholesterol in normal rats.

Casuarinin, a hydrolyzable tannin, isolated from the bark, exhibited antiherpes virus activity by inhibiting viral attachment and penetration. 50% ethanolic extract of the bark exhibited significant increase in the tensile of the incision wounds.

Dosage: Stembark—3-6 g powder. (API, Vol. II.)... terminalia arjuna

Terminalia Paniculata

Roth.

Family: Combretaceae.

Habitat: Forests of Western Ghats and Eastern Ghats up to 1,200 m.

English: Flowering Murdah.

Folk: Kinjal (Maharashtra); Neemeeri, Nimiri (Andhra Pradesh); Pekadukkai (Tamil Nadu); Pilamuruthu, Pillamurda (Kerala). Kindal (trade).

Action: Bark—diuretic, cardiotonic. Juice of the bark, mixed with purified butter and rock-salt, is applied in parotitis.

The heartwood gave 3,3'-O-di- methylellagic acid and 3,4,3'-O-tri- methylflavellagic acid. A triterpene carboxylic acid, beta-sitosterol, a gly- coside 3,3'-di-O-methylellagic acid- 4-monoglucoside and O-pentamethyl flavellagic acid have been isolated.

The bark contains 14% tannins, also beta-sitosterol.... terminalia paniculata

Trachyspermum Roxburghianum

(DC.) Craib.

Synonym: Carum roxburghianum (DC.) Benth. & Hk. f.

Family: Umbelliferae; Apiaceae.

Habitat: Cultivated throughout India.

English: Ajmud.

Ayurvedic: Ajamodaa, Ajamoda, Ayamoda, Ajmoja, Dipyaka.

Unani: Karafs-e-Hindi.

Siddha/Tamil: Ashamtagam.

Action: Seeds—carminative, stomachic, stimulant, cardiac tonic.

Used for dyspepsia, vomiting, hiccough, bronchitis, asthma, and pain in bladder; also as an emmenagogue.

The seeds yield the coumarins— bergaptene, 7-methoxy-6-methyl cou- marin and umbelliferone. Beta-sitos- terol is also reported.

Major constituent of the essential oil from the seeds are d-limonene (35.1), alpha-terpinene (19.4), d-linalool (4.7), dl-terpineol (5.7) and dl-piperitone (13.6%). Thymol content is 1.7%.

The fruit (Ajmud) induced hyperac- tivity of the central nervous system in mice. It also exhibited activity against Entamoeba histolytica. The ketonic substances exhibit powerful antispas- modic activity.

The fruit left after the extraction of the essential oil showed pronounced cardiotonic activity.

The oil produced marked diuretic effect in rabbits. It lowered blood pressure in dogs and rats.... trachyspermum roxburghianum

Tribulus Terrestris

Linn.

Family: Zygophyllaceae.

Habitat: Throughout India, up to 5,400 m.

English: Land-Caltrops, Puncture Vine.

Ayurvedic: Gokshura, Gokshu- raka, Kshudra (Laghu) Gokharu, Shvadamshtraa, Swaadu-kantaka, Trikanta, Trikantaka. (Larger var. is equated with Pedalium murex Linn. The fruits of both the varieties are conical and have four spines, not three as the synonyms denote. Hence, Acanthospermum hispidum DC. and Martynia annua Linn. have been suggested as the source of Trikantaka.)

Unani: Khaar-e-Khasak Khurd.

Siddha: Sirunenunji, Nerinjil, Nerunjil.

Action: Fruits—diuretic, demulcent, anti-inflammatory, anabolic, spasmolytic, muscle relaxant, hypotensive, hypoglycaemic. Used in strangury, calculus affections, urolithiasis, crystalluria, urinary discharges, pruritus-ani, as a tonic in sexual inadequacy; also as a supporting medicine in cough and asthma. Leaf—diuretic, haemostatic. Root—stomachic, diuretic.

In addition to all these applications, The Ayurvedic Pharmacopoeia of India attributes cardiotonic properties to the root and fruit.

The plant contains saponins, which on hydrolysis yield sapogenins—dios- genin, gitogenin, chlorogenin, rusco- genin, 25D-spirosta-3, 5-diene, among others. Flavonoids—rutin, quercetin, kaempferol, kaempferol-3-glucoside and-rutinoside, and tribuloside have been isolated from the leaves and fruits. The seeds contain carboline alkaloids— harmane and harmine. Harmol is also reported from the herb.

A saponin (unidentified) is reported effective for treating angina pec- toris in people with coronary heart disease (406 cases were treated). (Natural Medicines Comprehensive Database, 2007.)

Diuretic (more than furosemide), proerectile aphrodisiac, hypotensive, hypolipidaemic, hypoglycaemic (40- 67% in diabetic mice) activities have been confirmed in several experimental studies. (Pub Med, Medline abstracts, 2003.)

Dosage: Fruit—3-6 g powder. (CCRAS.)... tribulus terrestris

Valeriana Dubia

Bunge.

Synonym: V. officinalis auct. non Linn.

Family: Valerianacea.

Habitat: Western Himalayas, Kashmir at Sonamarg at 2,4002,700 m.

English: Common Valerian.

Action: Rhizome and roots— sedative, hypotensive, cardiotonic; depressant on CNS, antispasmodic; used for hysteria, neurosis, nervousness, hypochondriasis.

The roots and rhizomes yielded alkaloids—dipyridylmethylketone, ac- tinidine, iso-valeramide and valerian- ine; sesquiterpene ketone-valeranone. Bornyl acetate is the major constituent of the root oil, 31.5%, whereas it is only 6.6% in leaf oil. Bornyl isovalerate is reported from the root oil.

Baalaka is a confusing synonym of Tagara. It should be equated with Pavo- nia odorata Willd. (Malvaceae).

Baalaka (syns: Ambu, Baala, Barhi- shtha, Hrivera, Jala, Kacha, Muurd- haja, Udichi, Udichya) is known as Sugandhabaalaa in Northern markets. In South India Coleus vettiveroides K. C. Jacob (Labiateae) is preferred as Baalaka. Delphinium brunonianum Royle (Ranunculaceae), with synonyms Kutila, Nata, Vakra, is also used as Tagara.

Valeriana leschenaultii DC. var. brunoniana C. B. Clarke.

Family: Valerianaceae.

Habitat: The temperate Himalayas from Kashmir to Bhutan at altitudes of 1,200-3,60 m and in the Khasi and Jaintia hills between 1,500 and 1,800 m.

Folk: Sugandhabaalaa, Tagger, Taggar-ganthodaa. Asaarun (Ku- maon).

Action: Used as V. jatamansi and V officinalis.

Valeriana hardwickii is known as Taggar-ganthodaa in Mumbai and Asaarun in Kumaon. In Unani medicine, Asaarun is equated with Asarum europaeum Linn. (Aristolochiaceae). It is known as Subul-e-barri, Naardin- barri and Persian Tagar; Wild Nard, Hazel Wort and Asarabacca in English. Though sedative and brain tonic, Asaarun should not be equated with Tagara.

Family: Valerianaceae.

Habitat: Karnakata and the Nilgiris.

Ayurvedic: Tagara (related species).

Folk: Sugandhabaalaa, Taggar, Baalaka.

Action: Used as a substitute for valerian.... valeriana dubia

Motherwort

Leonurus cardiaca L. German: Herzgespann. French: Agripaume. Spanish: Agripalma. Italian: Cardiaca. Chinese: T’ui. Part used: herb.

Constituents: flavonoids, iridoids including rutin, diterpenes.

Action: antispasmodic, laxative, diaphoretic, emmenagogue, vaso-constrictor. (Simon Mills) Nerve and heart sedative. Hypotensive. Action similar to Valerian. (Dr Rudolf F. Weiss) Cardiotonic.

Uses: angina on effort, simple uncomplicated heart conditions to enhance exercise duration; tachycardia from hyperactive thyroid, hypertension, absent or painful menstruation (hence its name), menopausal flushes, schizophrenic tendency, pre-menstrual tension.

“Drink Motherwort tea and live to be a source of continuous astonishment and frustration to waiting heirs.” (Old saying)

Not given in pregnancy.

Combines well with Vervain (equal parts) for relaxing nervine.

Practitioner combinations: Menstrual disorders, equal parts: Black Cohosh, Cramp bark, Motherwort. Heart disorders: Motherwort 1; Hawthorn 1; Lily of the Valley half.

Benzodiazepine addiction to assist withdrawal: equal parts, Motherwort, Skullcap and Valerian. Infusions, extracts or tinctures.

Preparations: Thrice daily.

Tea: 1-2 teaspoons to each cup boiling water; infuse 15 minutes. Half-1 cup.

Tea combination: equal parts, Motherwort, Balm and Lime flowers. 2 teaspoons to cup boiling water: infuse 15 minutes, 1 cup thrice daily. Angina and heart symptoms – to ameliorate.

Liquid Extract: 1:1, 25 per cent alcohol. Dose: 2-4ml (30-60 drops).

Tincture: 1:5, 25 per cent alcohol. Dose: 5-10ml (1-2 teaspoons).

Powders. 2 to 4g.

Tablets/capsules. Popular combination. Powdered extract Motherwort 4:1 – 50mg. Powdered Passion flower BHP (1983) – 90mg. Powdered extract Lime flowers 3:1 – 67mg. For a calming and sedating effect in stressful situations and insomnia. (Gerard House)

Note: Motherwort needs to be taken for weeks. ... motherwort

Viola Sylvestris

Lam. (in part)

Family: Violaceae.

Habitat: Kashmir at 1,200-2,400 m.

English: Pale Wood Violet, Wood Violet.

Unani: Banafashaa (related species).

Action: Plant—pectoral, bechic; used in chest troubles. Stem, leaf and flower—applied to foul sores and wounds.

Habitat: Native to Europe; grown as an ornamental.

English: Heartsease, Wild Pansy.

Unani: Banafashaa (related species).

Action: Herb—anti-inflammatory, antiallergic, expectorant, diuretic, antirheumatic, alterative. Used for bronchitis, rheumatism, chronic skin disorders and for preventing capillary haemorrhage when under corticosteroid therapy. Root— antidysenteric; used as a substitute for Cephaelis ipecacuanha.

Key application: Externally in mild seborrheic skin diseases and milk scall in children. (German Commission E.) The British Herbal Pharmacopoeia recognizes the herb as an expectorant and dermatological agent.

The herb contains rutin, violin and salicylic acid. The flower contains rutin, quercetin, violanthin (6,8-digly- coside of apigenin), violaxanthin, p- hydroxycinnamic acid and delphini- din. A flavone C-glycoside-saponarin has also been obtained from flowers. Flowers, in addition, contain 15-cis- violaxanthin.

The herb exhibits anticoagulant property and diminishes the aggregation of platelets. It can be used as a preventive measure against thrombosis.

Habitat: Temperate Himalayas from Kashmir to Nepal between 1,200 and 2,700 m (a semiparasitic plant).

English: European Mistletoe.

Ayurvedic: Bandaaka, Suvarna- bandaaka. Vrikshaadani (substitute).

Unani: Kishmish Kaabuli.

Action: Vasodilator, cardiac depressant, tranquiliser, stimulates the vagus nerve which slows the pulse, anti-inflammatory, diuretic, immune enhancer, antineoplas- tic. Used for hypertension and tachycardia, as a nervine tonic.

The extract of leafy twigs is anti- inflammatory exerting an action upon capillary permeability and oedema. It stimulates granulation and the neoformation of connective tissue.

Key application: For treating degenerative inflammation of the joints by stimulating cuti- visceral reflexes following local inflammation brought about by intradermal injections; as palliative therapy for malignant tumour through non-specific stimulation. (German Commission E.)

Mistletoe contains glycoproteins; flavonoids, usually quercetin-derived (dependent on host tree to some extent); polypeptides; phenylcarboxylic acids; polysaccharides (including viscid acid); alkaloids; lignans.

Cardiotonic activity is due to the lig- nans. The polysaccharides stimulate the immune response. Antineoplas- tic activity is claimed to be responsible for prolongation of survival time in cancer patients. Polypeptides (visco- toxins) inhibit tumours and stimulate immune resistance. (For uses of lectin from Mistletoe in cancer, see Eur J cancer, 2001, Jan, 37(1), 23-31; Eur J Cancer 2001, 37 (15), 19101920.) (For application in hepatitis, see Fitoterapia, 70, 2001.)... viola sylvestris

Zingiber Officinale

Rosc.

Family: Zingiberaceae.

Habitat: Native to Southeast Asia; now cultivated mainly in Kerala, Andhra Pradesh, Uttar Pradesh, West Bengal, Maharashtra.

English: Ginger.

Ayurvedic: Fresh rhizome— Aardraka, Aadrikaa, Shrngibera, shrngavera, Katubhadra. Dried rhi- zome—Shunthi, Naagara, Naagaraa, Naagaraka, Aushadha, Mahaushad- ha, Vishvaa, Vishvabheshaja, Vishvaaushadha.

Unani: Fresh rhizome—Zanjabeel- e-Ratab, Al-Zanjabeel. Dried rhizome—zanjabeel, Zanjabeel-e- yaabis.

Siddha: Fresh rhizome—Inji, Allam, Lokottai. Dried rhizome— chukku, Sunthi.

Action: Rhizome—antiemetic, antiflatulent, hypocholesterolaemic, anti-inflammatory, antispasmodic, expectorant, circulatory stimulant, diaphoretic, increases bioavailabil- ity of prescription drugs. Used for irritable bowel and diarrhoea, colds and influenza. Showed encouraging results in migraine and cluster headache (J Ethnophar- macol, 1990, 29, 267-273; Aust J Med Herbalism, 1995, 7/3, 6978; Natural Medicines Comprehensive Database, 2007.) The Ayurvedic Pharmacopoeia of India recommends dried rhizomes in dyspepsia, loss of appetite, tympanitis, anaemia, rheumatism, cough and dyspnoea; fresh rhizomes in constipation, colic, oedema and throat infections.

Key application: For dyspepsia and prevention of motion sickness (German Commission E); vomiting of pregnancy, anorexia, bronchitis and rheumatic complaints (The British Herbal Compendium); as a post-operative antiemetic. (ESCOP).

The rhizome contains an essential oil containing monoterpenes, mainly geranial and neral; and sesquiterpenes, mainly beta-sesquiphellandrene, beta- bisabolene, ar-curcumene and alpha- zingiberene; pungent principles, consisting of gingerols, shogaols and related phenolic ketone derivatives. Other constituents include diarylheptenones, diterpenes, gingesulphonic acid and monoacyldigalactosyl glycerols.

Gingerol and shogaol have been shown to suppress gastric contractions. Both fresh and dried rhizomes suppress gastric secretion and reduce vomiting. Gingerol and shogaol have gained importance due to their sedative, anti-inflammatory, antipyretic, analgesic, hypotensive and hepatopro- tective activities.

Cardiotonic effects of ginger has been attributed to 6-and 8-shagaols and gingerols. (Antithrombotic effects remain unconfirmed.) Antimigraine effect is due to ginger's ability to decrease platelet aggregation. It also acts as a potent inhibitor of prostaglandins which enhance release of substance P from trigeminal fibers. (PDR, 2004.)

Indian ginger is considered only second to Jamaican in quality.

There are three main types of Indian ginger—Cochin ginger (light brown or yellowish grey; Calicut ginger from Malabar (orange or reddish brown, resembling African ginger) and Kolkata ginger (greyish brown to greyish blue).... zingiber officinale

Coronary Heart Disease

The cause of: coronary occlusion, coronary blockage, coronary thrombosis. A heart attack occurs when a coronary artery becomes blocked by swellings composed, among other things, of cholesterol. Such swellings may obstruct the flow of blood leading to a blood clot (thrombus). Cholesterol is a major cause of CHD.

Coronary thrombosis is more common in the West because of its preference for animal fats; whereas in the East fats usually take the form of vegetable oils – corn, sunflower seed, sesame, etc. Fatty deposits (atheroma) form in the wall of the coronary artery, obstructing blood-flow. Vessels narrowed by atheroma and by contact with calcium and other salts become hard and brittle (arterio-sclerosis) and are easily blocked. Robbed of oxygen and nutrients heart muscle dies and is replaced by inelastic fibrous (scar) tissue which robs the heart of its maximum performance.

Severe pain and collapse follow a blockage. Where only a small branch of the coronary arterial tree is affected recovery is possible. Cause of the pain is lack of oxygen (Vitamin E). Incidence is highest among women over 40 who smoke excessively and who take The Pill.

The first warning sign is breathlessness and anginal pain behind the breastbone which radiates to arms and neck. Sensation as if the chest is held in a vice. First-line agent to improve flow of blood – Cactus.

For cholesterol control target the liver. Coffee is a minor risk factor.

Measuring hair calcium levels is said to predict those at risk of coronary heart disease. Low hair concentrations may be linked with poor calcium metabolism, high aortic calcium build-up and the formation of plagues. (Dr Allan MacPherson, nutritionist, Scottish Agricultural College, Ayr, Scotland)

Evidence has been advanced that a diagonal ear lobe crease may be a predictor for coronary heart disease. (American Journal of Cardiology, Dec. 1992)

Tooth decay is linked to an increased risk of coronary heart disease and mortality, particularly in young men. (Dr Frank De Stefano, Marshfield Medical Research Foundation, Wisconsin, USA) Treatment. Urgency. Send for doctor or suitably qualified practitioner. Absolute bedrest for 3 weeks followed by 3 months convalescence. Thereafter: adapt lifestyle to slower tempo and avoid undue exertion. Stop smoking. Adequate exercise. Watch weight.

Cardiotonics: Motherwort, Hawthorn, Mistletoe, Rosemary. Ephedra, Lily of the Valley, Broom.

Cardiac vasodilators relax tension on the vessels by increasing capacity of the arteries to carry more blood. Others contain complex glycosides that stimulate or relax the heart at its work. Garlic is strongly recommended as a preventative of CHD.

Hawthorn, vasodilator and anti-hypertensive, is reputed to dissolve deposits in thickened and sclerotic arteries BHP (1983). It is believed to regulate the balance of lipids (body fats) one of which is cholesterol.

Serenity tea. Equal parts: Motherwort, Lemon Balm, Hawthorn leaves or flowers. 1 heaped teaspoon to each cup boiling water; infuse 5-15 minutes; 1 cup freely.

Decoction. Combine equal parts: Broom, Lily of the Valley, Hawthorn. 1-2 teaspoons to each cup water gently simmered 20 minutes. Half-1 cup freely.

Tablets/capsules. Hawthorn, Motherwort, Cactus, Mistletoe, Garlic.

Practitioner. Formula. Hawthorn 20ml; Lily of the Valley 10ml; Pulsatilla 5ml; Stone root 5ml; Barberry 5ml. Tincture Capsicum 1ml. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Thrice daily in water or honey.

Prevention: Vitamin E – 400iu daily.

Diet. See: DIET – HEART AND CIRCULATION.

Supplements. Daily. Vitamin C, 2g. Vitamin E possesses anti-clotting properties, 400iu. Broad spectrum multivitamin and mineral including chromium, magnesium selenium, zinc, copper.

Acute condition. Strict bed-rest; regulate bowels; avoid excessive physical and mental exertion. Meditation and relaxation techniques dramatically reduce coronary risk. ... coronary heart disease

Leukaemia

Greek word ‘white blood’. (Leukosis) Acute myeloid and lymphoblastic. Cancer of the white blood cells of two main types; myeloid, involving the polymorph type and lymphatic involving lymphocytes. Each type may take acute or chronic form, the acute being more serious. The disease is not an infection.

Causes: exposure to chemicals, X-rays or radioactive material. Genetic factors are believed to predispose. The condition may be acute or chronic and may follow chemotherapy.

Remissions are known to have been induced by a preparation from the Periwinkle plant (Vinca rosea) now re-classified as Catharanthus roseus.

“Smokers suffer a significantly increased risk of developing acute myelocytic leukaemia.” (“Cancer”: 1987 vol 60, pp141-144)

Acute Leukaemia. Rapid onset with fatality within weeks or months. Fever. Proliferation of white cells in the bone marrow which are released and blood-borne to the liver, spleen and lymphatics. There may be bleeding from kidneys, mouth, bowel and beneath the skin. (Shepherd’s Purse, Yarrow) The acute form is known also as acute lymphoblastic or acute myeloblastic leukaemia. May be mis-diagnosed as tuberculosis.

Chronic Leukaemia. Gradual onset. Breathlessness from enlargement of the spleen. Swelling of glands under arms, in neck and groin. Loss of weight, appetite, strength, facial colour and body heat. Anaemia, spontaneous bleeding and a variety of skin conditions. Diarrhoea. Low grade fever.

No cure is known, but encouraging results in orthodox medicine promise the disease may be controlled, after the manner of diabetes by insulin. Successful results in such control are reported by Dr Hartwell, National Cancer Institute, Maryland, USA, with an alkaloid related to Autumn Primrose (Colchicum officinale). Vinchristine, a preparation from Periwinkle is now well-established in routine treatment. Red Clover, also, is cytotoxic to many mammalian cells. Vitamin C (present in many herbs and fruits) inhibits growth of non-lymphoblastic leukaemia cells. Good responses have been observed by Dr Ferenczi, Hungary, by the use of raw beet root juice.

Also treated with success by Dr Hartland (above) has been lymphocytic leukaemia in children which he treated with a preparation from Periwinkle.

Choice of agents depends largely upon the clinical experience of the practitioner and ease of administration. Addition of a nerve restorative (Oats, Kola, Black Cohosh or Helonias) may improve sense of well-being. To support the heart and circulatory system with cardiotonics (Hawthorn, Motherwort, Lily of the Valley) suggests sound therapy.

Herbal treatment may favourably influence haemoglobin levels and possibly arrest proliferation of leukaemic cells and reduce size of the spleen. It would be directed towards the (a) lymphatic system (Poke root), (b) spleen (Tamarinds), (c) bone marrow (Yellow Dock), and (d) liver (Blue Flag root).

An older generation of herbalists prescribed Blue Flag root, Yellow Dock, Poke root, Thuja and Echinacea, adding other agents according to indications of the particular case.

Tea. Formula. Equal parts: Red Clover, Gotu Kola, Plantain. 1-2 teaspoons to each cup boiling water; infuse 10-15 minutes. 1 cup thrice daily.

New Jersey tea (ceanothus). 1 teaspoon to each cup boiling water. Half-1 cup thrice daily.

Periwinkle tea (Vinca rosea). 2 teaspoons to each cup boiling water; infuse 15 minutes. 1 cup thrice daily.

Decoction. Formula. Equal parts: Echinacea, Yellow Dock, Blue Flag root. 1 teaspoon to each cup water gently simmered 20 minutes. 1 cup before meals thrice daily.

Formula. Red Clover 2; Yellow Dock 1; Dandelion root 1; Thuja quarter; Poke root quarter; Ginger quarter. Dose: Liquid Extract: 1 teaspoon. Tinctures: 1-2 teaspoons. Powders: 500mg (two 00 capsules or one-third teaspoon). Thrice daily.

Vinchristine. Dosage as prescribed. In combination with other medicines.

Wheatgrass. Juice of fresh Wheatgrass grown as sprouts and passed through a juicer. Rich in minerals. One or more glasses daily.

Beetroot juice. Rich in minerals. Contains traces of rare rabidium and caesium, believed to contribute to anti-malignancy effect. (Studies by Dr A. Ferenczi, Nobel Prize-winner, published 1961)

Diet: Dandelion coffee.

Supplements. B-complex, B12, Folic acid, Vitamin C 2g morning and evening, Calcium ascorbate 2g morning and evening. Copper, Iron, Selenium, Zinc.

Childhood Leukaemia. Research has linked the disease with fluorescent lighting. “Fluorescent tubes emit blue light (400mm wavelength). Light penetrates the skin and produces free radicals. Free radicals damage a child’s DNA. Damaged DNA causes leukaemia to develop. The type and intensity of lighting in maternity wards should be changed. This could be prevented by fitting cheap plastic filters to fluorescent lights in maternity wards.” (Peter Cox, in “Here’s Health”, on the work of Dr Shmuel Ben-Sasson, The Hubert Humphrey Centre of Experimental Medicine and Cancer Research, Jerusalem)

Treatment by hospital specialist. ... leukaemia




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