Cerebr Health Dictionary

Cerebr: From 1 Different Sources


Cerebral Palsy

The term used to describe a group of conditions characterised by varying degrees of paralysis and originating in infancy or early childhood. In some 80 per cent of cases this takes the form of spastic paralysis (muscle sti?ness), hence the now obsolete lay description of sufferers as ‘spastics’. The incidence is believed to be around 2 or 2·5 per 1,000 of the childhood community. In the majority of cases the abnormality dates from well before birth: among the factors are some genetic malformation of the brain, a congenital defect of the brain, or some adverse e?ect on the fetal brain as by infection during pregnancy. Among the factors during birth that may be responsible is prolonged lack of oxygen such as can occur during a di?cult labour; this may be the cause in up to 15 per cent of cases. In some 10–15 per cent of cases the condition is acquired after birth, when it may be due to KERNICTERUS, infection of the brain, cerebral thrombosis or embolism, or trauma. Acute illness in infancy, such as meningitis, may result in cerebral palsy.

The disease manifests itself in many ways. It may not be ?nally diagnosed and characterised until the infant is two years old, but may be apparent much earlier – even soon after birth. The child may be spastic or ?accid, or the slow, writhing involuntary movements known as athetosis may be the predominant feature. These involuntary movements often disappear during sleep and may be controlled, or even abolished, in some cases by training the child to relax. The paralysis varies tremendously. It may involve the limbs on one side of the body (hemiplegia), both lower limbs (paraplegia), or all four limbs (DIPLEGIA and QUADRIPLEGIA). Learning disability (with an IQ under 70) is present in around 75 per cent of all children but children with diplegia or athetoid symptoms may have normal or even high intelligence. Associated problems may include hearing or visual disability, behavioural problems and epilepsy.

The outlook for life is good, only the more severely affected cases dying in infancy. Although there is no cure, much can be done to help these disabled children, particularly if the condition is detected at an early stage. Assistance is available from NHS developmental and assessment clinics, supervised by community paediatricians and involving a team approach from experts in education, physiotherapy, occupational therapy and speech training. In this way many of these handicapped children reach adulthood able to lead near-normal lives. Much help in dealing with these children can be obtained from SCOPE (formerly the Spastics Society), and Advice Service Capability Scotland (ASCS).... cerebral palsy

Cerebrospinal Fluid

The ?uid within the ventricles of the brain and bathing its surface and that of the spinal cord. Normally a clear, colourless ?uid, its pressure when an individual is lying on one side is 50 to 150 mm water. A LUMBAR PUNCTURE should not be done if the intracranial pressure is raised (see HYDROCEPHALUS).

The cerebrospinal ?uid (CSF) provides useful information in various conditions and is invaluable in the diagnosis of acute and chronic in?ammatory diseases of the nervous system. Bacterial MENINGITIS results in a large increase in the number of polymorphonuclear LEUCOCYTES, while a marked lymphocytosis is seen in viral meningitis and ENCEPHALITIS, tuberculous meningitis and neurosyphilis. The total protein content is raised in many neurological diseases, being particularly high with neuro?bromatosis (see VON RECKLINGHAUSEN’S DISEASE) and Guillan-Barré syndrome, while the immunoglobulin G fraction is raised in MULTIPLE SCLEROSIS (MS), neurosyphilis, and connective-tissue disorders. The glucose content is raised in diabetes (see DIABETES MELLITUS), but may be very low in bacterial meningitis, when appropriately stained smears or cultures often de?ne the infecting organism. The CSF can also be used to measure immune proteins produced in response to infection, helping diagnosis in cases where the organism is not grown in the laboratory culture.... cerebrospinal fluid

Cerebrovascular Accident

See STROKE.... cerebrovascular accident

Cerebral Thrombosis

Formation of a blood clot within vessels of the brain. May be due to atheroma or embolism causing a blockage resulting in hypoxia (oxygen deficiency).

Alternatives. Teas. Lime flowers, Nettles, Horsetail, Ginkgo, Oats, Mistletoe, Yarrow.

Tea. Mix equal parts: Ginkgo, Hawthorn, Yarrow. One heaped teaspoon to each cup boiling water; infuse 5-10 minutes; 1 cup thrice daily.

Tablets/capsules. Ginkgo, Hawthorn, Prickly Ash.

Diet. See: DIET–HEART AND CIRCULATION.

Supplements. Daily: Vitamin E 1000mg; B6 50mg; B12 2mcg. Selenium 200mcg; Zinc 15mg. Strict bedrest; regulate bowels; avoid excessive physical and mental exertion. ... cerebral thrombosis

Cerebral Haemorrhage

Bleeding within the brain due to a ruptured blood vessel (see intracerebral haemorrhage; stroke).... cerebral haemorrhage

Cerebrovascular Disease

Any disease affecting an artery in, and supplying blood to, the brain: for example, atherosclerosis (narrowing of the arteries) or defects or weaknesses in arterial walls causing aneurysm (a balloon-like swelling in an artery).

The disease may eventually cause a cerebrovascular accident, which commonly leads to a stroke.

Extensive narrowing of blood vessels throughout the brain can be a cause of dementia.... cerebrovascular disease

Cerebrum

The largest and most developed part of the brain, the site of most conscious and intelligent activities. Its main components are 2 large cerebral hemispheres that grow out from the upper part of the brainstem. Their surface is made up of a series of folds called gyri, separated by fissures called sulci, with a deep longitudinal fissure separating the 2 hemispheres. The 4 main surface regions of each hemisphere – the frontal, parietal, temporal, and occipital lobes – are named after their overlying bones. Each hemisphere has a central cavity, called a ventricle, filled with cerebrospinal fluid. This is surrounded by an inner layer, consisting of clusters of nerve cells called the basal ganglia. A middle layer of “white matter” is composed mainly of nerve fibres, which carry information between specific areas of the cortex and between areas of the cortex, central brain, and the brainstem. A thick band of fibres

called the corpus callosum carries nerve signals between the 2 hemispheres.

The outer surface layer of each hemisphere is the cerebral cortex – the “grey matter’’, where much of the sensory information from organs such as the eyes and ears is processed. Specific sensory processing takes place in separate regions. For example, visual perception is located in a part of the occipital lobe called the visual cortex.

The cortex also contains “motor’’ areas concerned with the initiation of signals for movement by the skeletal muscles.

Linked to the sensory and motor areas of the cortex are association areas, which integrate information from various senses and also perform functions such as comprehension and recognition, memory storage and recall, thought and decision making.

Some of these cortical functions are localized to one “dominant’’ hemisphere (the left in almost all right-handed and many left-handed people).

Two clearly defined areas in the dominant hemisphere are Wernicke’s area, responsible for the comprehension of words, and Broca’s area, which is concerned with language expression.... cerebrum

Cerebellum And Cerebrum

See BRAIN.... cerebellum and cerebrum

Cerebropathy

Any disorder of the brain... cerebropathy

Acervulus Cerebri

a collection of granules of calcium-containing material that is sometimes found within the *pineal gland as its calcification proceeds (normally after the 17th year): ‘brain sand’.... acervulus cerebri

Cerebral Abscess

see abscess.... cerebral abscess

Cerebral Aqueduct

(aqueduct of Sylvius) the narrow channel, containing cerebrospinal fluid, that connects the third and fourth *ventricles of the brain.... cerebral aqueduct

Cerebral Hemisphere

one of the two paired halves of the *cerebrum.... cerebral hemisphere

Cerebral Cortex

the intricately folded outer layer of the *cerebrum, making up some 40% of the brain by weight and composed of an estimated 15 thousand million neurons (see grey matter). This is the part of the brain most directly responsible for consciousness, with essential roles in perception, memory, thought, mental ability, and intellect, and it is responsible for initiating voluntary activity. It has connections, direct or indirect, with all parts of the body. The folding of the cortex provides a large surface area, the greater part lying in the clefts (sulci), which divide the upraised convolutions (gyri). On the basis of its microscopic appearance in section, the cortex is mapped into *Brodmann areas; it is also divided into functional regions; including *motor cortex, *sensory cortex, and *association areas. Within, and continuous with it, lies the *white matter, through which connection is made with the rest of the nervous system.... cerebral cortex

Cerebral Tumour

an abnormal multiplication of brain cells. Any tumorous swelling tends to compress or even destroy the healthy brain cells surrounding it and – because of the rigid closed nature of the skull – increases the pressure on the brain tissue. Malignant brain tumours, which are much more common in children than in adults, include *medulloblastomas and *gliomas; these grow rapidly, spreading through the otherwise normal brain tissue and causing progressive neurological disability. Benign tumours, such as *meningiomas, grow slowly and compress the brain tissue. Both benign and malignant tumours commonly cause fits. Benign tumours are often cured by total surgical resection. Malignant tumours may be treated by neurosurgery, chemotherapy, and radiotherapy, but the outcome for most patients remains poor.... cerebral tumour

Cerebral Venous Sinus Thrombosis

the presence of thrombosis in the dural venous sinuses, which drain blood from the brain. Symptoms may include headache, abnormal vision, any of the symptoms of stroke (such as weakness of the face and limbs on one side of the body), and seizures. Treatment is with anticoagulants.... cerebral venous sinus thrombosis

Cerebration

n. 1. the functioning of the brain as a whole. 2. the unconscious activities of the brain.... cerebration

Cerebroside

n. one of a group of compounds occurring in the *myelin sheaths of nerve fibres. They are *glycolipids, containing a sphingolipid bound to a sugar, usually galactose (in galactocerebrosides) or glucose (in glucocerebrosides).... cerebroside

Cerebrospinal Fever

(spotted fever) see meningitis.... cerebrospinal fever

Pseudotumour Cerebri

see idiopathic intracranial hypertension.... pseudotumour cerebri

Cerebral

pertaining to the largest part of the brain, the cerebrum.... cerebral



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