the intricately folded outer layer of the *cerebrum, making up some 40% of the brain by weight and composed of an estimated 15 thousand million neurons (see grey matter). This is the part of the brain most directly responsible for consciousness, with essential roles in perception, memory, thought, mental ability, and intellect, and it is responsible for initiating voluntary activity. It has connections, direct or indirect, with all parts of the body. The folding of the cortex provides a large surface area, the greater part lying in the clefts (sulci), which divide the upraised convolutions (gyri). On the basis of its microscopic appearance in section, the cortex is mapped into *Brodmann areas; it is also divided into functional regions; including *motor cortex, *sensory cortex, and *association areas. Within, and continuous with it, lies the *white matter, through which connection is made with the rest of the nervous system.
The outer covering of the two adrenal glands that lie atop each kidney. Embryonically derived from gonad tissue, they make steroid hormones that control electrolytes, the management of fuels, the rate of anabolism, the general response to stress, and maintenance of nonspecific resistance.... adrenal cortex
the presence of thrombosis in the dural venous sinuses, which drain blood from the brain. Symptoms may include headache, abnormal vision, any of the symptoms of stroke (such as weakness of the face and limbs on one side of the body), and seizures. Treatment is with anticoagulants.... cerebral venous sinus thrombosis
an abnormal multiplication of brain cells. Any tumorous swelling tends to compress or even destroy the healthy brain cells surrounding it and – because of the rigid closed nature of the skull – increases the pressure on the brain tissue. Malignant brain tumours, which are much more common in children than in adults, include *medulloblastomas and *gliomas; these grow rapidly, spreading through the otherwise normal brain tissue and causing progressive neurological disability. Benign tumours, such as *meningiomas, grow slowly and compress the brain tissue. Both benign and malignant tumours commonly cause fits. Benign tumours are often cured by total surgical resection. Malignant tumours may be treated by neurosurgery, chemotherapy, and radiotherapy, but the outcome for most patients remains poor.... cerebral tumour