Chancroid Health Dictionary

Gram-negative (see GRAM’S STAIN), rod-like, aerobic, non-sporing and non-motile parasitic bacteria. Mostly found in the respiratory tract, they may be part of the normal ?ora, but may also be responsible for several diseases. The main pathogenic species of haemophilus is H. in?uenzae, which may cause severe exacerbations of chronic BRONCHITIS, as well as MENINGITIS, EPIGLOTTITIS, SINUSITIS, and otitis media (see EAR, DISEASES OF). Other species may cause conjunctivitis (see EYE, DISORDERS OF) or CHANCROID. Haemophilus species are sensitive to a wide range of antibiotics, though generally resistant to penicillin. Infants are routinely immunised with Haemophilus B vaccine to prevent meningitis, septicaemia and epiglottitis

– all potentially fatal disesases.... haemophilus

Enlarged lymph gland containing pus. Often in the groin. Seen especially in Bubonic Plague, Lymphogranuloma venereum and chancroid.... bubo

Sexually transmitted diseases – traditionally called venereal diseases – are infections transmitted by sexual intercourse (heterosexual and homosexual). In the United Kingdom they are treated in genito-urinary medicine (GUM) clinics. The incidences of these diseases are more common among people who have several sexual partners, as STDs are very infectious; some of the major STDs, particularly AIDS/HIV, are also transmitted by blood and so can result from needle-sharing by drug addicts, or by TRANSFUSION. The ‘traditional’ STDs – SYPHILIS, GONORRHOEA and CHANCROID – now comprise only 10 per cent of all such diseases treated in STD clinics: these clinics also treat patients with CHLAMYDIA, TRICHOMONIASIS, HERPES GENITALIS, MOLLUSCUM CONTAGIOSUM and genital WARTS. SCABIES and pubic lice (see PEDICULOSIS – Pediculus pubis) can also be transmitted by sexual intercourse, and HEPATITIS B is also recognised as an STD.

The incidence of STDs rose sharply during World War II but the advent of PENICILLIN and subsequent antibiotics meant that syphilis and gonorrhoea could be treated e?ectively. The arrival of oral contraception and more tolerant public attitudes to sexual activities resulted in an increase in the incidence of sexually transmitted infections. The diagnosis of NONSPECIFIC URETHRITIS (NSU), once given to many patients whose symptoms were not due to the traditional recognised infections, was in the 1970s realised to be wrong, as the condition was proved to be the result of infection by chlamydia.

Most STDs are treatable, but herpes is an infection that could become chronic, while hepatitis B and, of course, AIDS/HIV are potentially fatal – although treatment of HIV is now proving more e?ective. As well as the treatment and subsequent monitoring of patients with STDs, one of the important functions of clinics has been the tracing, treatment and follow-up of sexual contacts of infected individuals, a procedure that is conducted con?dentially.

Apart from AIDS/HIV, the incidence of STDs fell during the 1980s; however in some countries the agents causing syphilis and gonorrhoea began to develop resistance to antibiotics, which showed the continued importance of practising safe sex – in particular by restricting the number of sexual partners and ensuring the regular use of condoms. In the United Kingdom the rates per million of the male population infected by syphilis rose from 8.8 in 1991 to 9.7 in 1999; in females the ?gures were 4.0 to 4.5, respectively. For gonorrhoea, the ?gures for men were 399.4 in 1991 and 385 in 1999, with women also showing a reduction, from

216.5 to 171.3. In 1991, 552.6 per million of men had chlamydia, a ?gure which rose to

829.5 in 1999; for women in the same period the incidence also rose, from 622.5 to 1,077.1 per million. For genital herpes simplex virus, the infection rate for men fell from 236.6 per million to 227.7, whereas the ?gures for women showed a rise, 258.5 to 357. The incidence of AIDS/HIV is given under the relevant entry. (These ?gures are based on information in United Kingdom Health Statistics, 2001 edition, UKHSI, published by the O?ce of National Statistics.)... sexually transmitted diseases (stds)

An eroded area of skin on the genitalia.

The most common cause is a sexually transmitted infection, particularly syphilis and genital herpes (see herpes, genital).

Chancroid and granuloma inguinale are tropical bacterial infections that cause genital ulcers.

Lymphogranuloma venereum is a viral infection producing genital blisters.

Behçet’s syndrome is a rare condition that causes tender, recurrent ulcers in the mouth and on the genitals.

Cancer of the penis or vulva may first appear as a painless ulcer with raised edges.... genital ulcer

(chancroid) a sexually transmitted disease caused by the bacterium Haemophilus ducreyi, resulting in enlargement and ulceration of lymph nodes in the groin. Treatment with sulphonamides is effective.... soft sore

A general term for procedures by which blood or tissues are classified (see blood groups; tissue-typing).

ulcer An open sore appearing on the skin or on a mucous membrane that results from the destruction of surface tissue. Ulcers may be shallow, or deep and crater-shaped, and they are usually inflamed and painful.

Skin ulcers most commonly occur on the leg (see leg ulcer), usually as the result of inadequate blood supply to, or drainage from, the limb. In some cases skin cancers, particularly basal cell carcinomas or squamous cell carcinomas, may be ulcerated. Rarely, a cancer may develop in the skin at the edge of a longstanding ulcer.

The most common types of ulcers of the mucous membranes are mouth ulcers, peptic ulcers, and those that occur in ulcerative colitis.

Ulcers may also affect the skin or mucous membranes of the genitalia

(see genital ulcer). Most genital ulcers are caused by sexually transmitted infections. Examples of this type of ulcer are hard chancres (see chancre, hard), which develop during the first stage of syphilis, and soft chancres (see chancroid). In addition, ulcers may develop on the cornea (see corneal ulcers).... typing