Chitra Health Dictionary

Hance

Family: Zingiberaceae.

Habitat: Native to China; cultivated in northern India.

English: Lesser Galangal, Alpinia, Catarrh Root, Chinese Ginger.

Ayurvedic: Kulanjan (var.). Unani: Khulanjaan (smaller var.). Siddha/Tamil: Chitrarattai.

Action: Rhizome—a circulatory stimulant and carminative.

Key application: As a carminative.

(The British Herbal Pharmacopoeia.)

Aqueous and methanolic extracts of the rhizome, on oral administration, exhibited significant decrease in gastric secretion in rabbits and showed anticholinergic effect in pylorus-ligated rats.

Flavones from rhizomes are strongly antifungal against a wide variety of pathogenic fungi, responsible for major skin diseases in eastern India. Flavones were also found to be active against a number of Gram-positive and Gram-negative bacteria.

The gingerols and diaryheptanoids constituents of the rhizome are potent inhibitors of PG synthetase (prosta- glandin biosynthesizing enzyme); they can also be active against 5-lipoxyge- nase, an enzyme involved in leuko- triene biosynthesis. (Natural Medicines Comprehensive Database, 2007.)... alpinia officinarum

(Wendl.) K.Schum.

Synonym: A. Zerumbet Burtt and R.M. Smith

Family: Zingiberaceae.

Habitat: Native to East Indies. Occurs in the eastern Himalayas from West Bengal eastwards.

English: Light Galangal.

Siddha/Tamil: Chitraraththai.

Action: Rhizomes are used as a substitute for A. galanga and even for ginger; antiulcerative, spasmolytic.

The leaves and rhizomes yield an essential oil which contains alpha-and beta-pinene, borneol, campene and ci- neole as major constituents.... alpinia speciosa

D. Don.

Synonym: B. bhojpattra Wall.

Family: Betulaceae.

Habitat: Temperate Himalaya from Kashmir to Bhutan.

English: Himalayan Silver Birch, Indian Paper tree.

Ayurvedic: Bhuurja, Bahulvalkala, Bahuputa, Lekhyapatraka, Charmi, Chitrapatra, Bhutahaa.

Folk: Bhojapatra.

Siddha/Tamil: Boorjapattram (leaves).

Action: Resin—laxative. Leaves— diuretic; used in the form of infusion in gout, rheumatism, dropsy, and as a solvent of stones in the kidneys; used in skin affections, especially eczema. Bark—used in convulsions. Oil—astringent, antiseptic.

Key application: (B. pendula) In irrigation therapy for bacterial and inflammatory diseases of the urinary tract and for kidney gravel; supportive therapy for rheumatic ailment. (German Commission E, ESCOP.)

European Silver Birch is equated with Betula alba L., synonym B. pendula Roth. Astringent, diuretic, anti- inflammatory, bitter, cholagogue; contains salicylates. Used for kidney and bladder complaints, sluggish kidney functions, rheumatism and gout. Methyl salicylate is obtained by distillation of the twigs. In an Indian sp., B. acuminata, methyl salicylate (92.8%) has been reported in the essential oil of the bark. B. utilis is also a close relative of B. pendula.

Dosage: Bark—3-5 g powder; decoction—50-100 ml (CCRAS.)... betula utilis

(Lam.) Kurz. 103 stearic, palmitic, myristic, oleic and Bryonopsis laciniosa

(Linn.) Naud.

Synonym: Bryonia laciniosa Linn. Diplocyclos palmatus Jeff.

Family: Cucurbitaceae.

Habitat: Throughout India.

English: Bryony.

Ayurvedic: Lingini, Shivalingi, Chitraphalaa.

Siddha/Tamil: Iyaveli, Iyaviraali.

Folk: Lingadonda (Telugu).

Action: Seeds—anti-inflammatory, spasmolytic. Used for vaginal dysfunctions, as a fertility promoting drug. Powdered seeds, also roots, are given to help conception in women. Plant is also used in venereal diseases.... bryophyllum pinnatum

Thunb.

Synonym: P. auriculata Lam.

Family: Plumbaginaceae.

Habitat: Native to South Africa; grown in gardens in India.

Ayurvedic: Nila-chitraka (blue- flowered var.). (Bears pale-blue flowers.)

Action: See P. zeylanica.... plumbago capensis

Schrad.

Family: Cucurbitaceae.

Habitat: Throughout India.

English: Colocynth Bitter Apple.

Ayurvedic: Indravaaruni, Indraval- li, Indravaarunikaa, Gavaakshi, Chitraa, Chitraphalaa, Indraasuri, Mrigaani, Mrigairvaaru, Vishaalaa, Vishaalyka, Indraayana. Ain- dri (also equated with Bacopa monnieri).

Unani: Hanzal.

Siddha/Tamil: Kumatti.

Action: Dried pulp of ripe fruit— cathartic, drastic purgative, irritant and toxic. The pulp is used for varicose veins and piles. A paste of root is applied to various inflammations and swellings. The cataplasm of leaves is applied in migraine and neuralgia.

The Ayurvedic Pharmacopoeia of India indicated the use of the fruit in jaundice; the root in diseases of the liver and spleen and the leaf in cutaneous affections and alopecia.

Colocynth contains up to 3% cucur- bitacin. The drug and its preparations cause drastic irritation of the gastrointestinal mucosa and haemorrhages.

Cucurbitacins include cucurbitacin E-, J-, L-glucosides. In addition, the pulp contains caffeic acid derivatives (chlorogenic acid).

Roots contain aliphatic compounds. Ethanolic extract (50%) shows significant anti-inflammatory activity in albino rats.

Leaves and flowers contain querce- tin and kaempferol. The ethanolic extract of leaves and flowers exhibits antibacterial activity against a number of Gram-positive and Gram-negative bacteria.

The powder is toxic at 0.6-1.0 g. The fruit exhibited carcinogenic activity in animal studies.

Dosage: Dried fruit—125-500 mg powder. (API Vol. III.) Root—1- 3 g. powder. (CCRAS.) Dried leaf— for external use. (API Vol. II.)... citrullus colocynthis

Burm. f.

Family: Myrsinaceae.

Habitat: Throughout India.

English: Embelia.

Ayurvedic: Vidanga, Krmighna, Krmihara, Krmiripu, Chitratandula, Jantughna, Jantunaashana, Vella, Amogha.

Unani: Baobarang, Barang Kaabuli.

Siddha/Tamil: Vaayuvidangam.

Action: Ascaricidal, anthelmintic, carminative, diuretic, astringent, anti-inflammatory, antibacterial, febrifuge. Used in diseases of chest and skin. Active principles are found to be oestrogenic and weakly progestogenic. Root—bechic, antidiarrhoeal. Seed—spermicidal, oxytocic, diuretic. The plant is also used for its blood purifying properties. It is an ingredient in cough syrups, preparations for anaemia, genitourinary tract infections, diarrhoea and diseases of the liver.

Embelin, isolated from the berries, shows significant anti-implantation and post-coital antifertility activity. (Successful trials have been carried out at the National Institute of Immunology, New Delhi on human beings.) It is found to be a potential male antifer- tility agent. Spermatogenesis has been impaired and sperm count reduced to the level of infertility. The antisper- matogenic changes are found to be reversible without any toxic effects.

Aqueous and EtOH extract of the fruit—anthelmintic against earthworms. Fruit powder (200 mg/kg), taken with curd on empty stomach, expelled tapeworm within 6-24 h. The treatment was also found effective in giardiasis. EtOH (50%) of the plant was found slightly active against E.coli. Di-salts of embelin—an- thelmintic. Amino salts exhibited less side effects than embelin. The effect of di-isobutyl amino derivatives lasted up to 10 h, also showed anti-inflammatory, hypotensive and antipyretic activities.

Berries gave quinones—embelin, ra- panone, homoembelin, homorapnone and vilangin.

Dosage: Fruit—5-10 g powder. (API Vol. I.)... embelia ribes

Hook. f.

Synonym: I. royleana auct. non-DC.

Family: Compositae; Asteraceae.

Habitat: Temperate and Alpine Himalayas from Chitral to Nepal at 1,500-4,200 m.

English: Elecampane.

Ayurvedic: Pushkaramuula, Pushkara, Paushkara, Padmapatra, Kaashmira, Kushtha-bheda.

Action: Antispasmodic, stomachic, antihistaminic, expectorant, anticatarrhal. Used for asthma, chronic bronchitis and pulmonary disorders.

Key application: Inula helenium— as expectorant. (The British Herbal Pharmacopoeia.)

Roots are used in Kashmir as adulterant of Saussurea lappa.

The root contains a volatile oil, about 1-4%; major constituents being in- ulin (10.0) and sesquiterpene lactones, mainly alantolactone, isoalantolactone and their dihydro derivatives. Alan- tolactone and others in the mixture known as helenalin (sesquiterpene lactones) are toxic constituents of the root.

Alantolactone is anti-inflammatory in animals and has been shown to stimulate the immune system. It is also hypotensive and anthelmintic in animals; antibacterial and antifungal in vitro It irritates mucous membranes. It is used as an anthelmintic in Europe and UK.

Plant extract showed potent antispasmodic effect against bronchial spasm induced by histamine and various plant pollens.

The root, when combined with Commiphora mukul gum-resin, acts as a hypolipidaemic agent, exhibits beta- blocking activity and beneficial effect in myocardial ischaemia.

The roots also exhibit sedative and blood pressure lowering activity.

The European species is equated with Inula helenium Linn.

Dosage: Root—1-3 g powder. (API Vol. IV.)... inula racemosa

Plumbago spp.

Plumbaginaceae

The genus Plumbago belonging to the family Plumbaginaceae is a popular and medicinally very important group of medicinal plants. Three species, namely P. rosea, P. zeylanica and P. auriculata have been identified. Among these P. rosea and P. zeylanica are important ones.

Plumbago, in general is an esteemed remedy for leucoderma and other skin diseases. The synonyms of fire like agnih, vahnih, etc. are attributed to this drug to indicate the very burning action of the root, causing blisters on the skin (daranah). The drug is used only after adequate curing and purification. Root is the officinal part and it enters into the composition of preparations like Citrakasavam, Dasamularista, Gulgulutiktaka kasaya, Yogarajachurna, etc.

1. P. rosea Linn. syn. P. indica Linn.

Eng: Rosy-flowered Leadwort; San: Citrakah, Dhahanah;

Hin: Lalcitra, Raktacitra;

Ben: Lalchita;

Mal: Kotuveli, Chettikkoduveli, Chuvannakotuveli;

Tam: Chenkotuveli, Cittiramulam;

Kan: Kempacitramula;

Tel: Yerracitramulam

Rosy-flowered leadwort or Fire plant is a native of Coromandel Coast. It is found throughout India, in moist situations as well as cultivated. The roots are useful in dyspepsia, colic, inflammations, cough, bronchitis, helmenthiasis, haemorrhoids, elephantiasis, chronic and intermittent fever, leprosy, leucoderma, ringworm, scabies, hepatosplenomegaly, amenorrhoea, odontalgia, vitiated conditions of vata, kapha and anaemia. It is a pretty subscandent perennial shrub with semi -woody striate stems and flexible branches. Leaves are simple, alternate oblong, short cuneate at the base passing into a very short amplexicaul, exauriculate, and reddish petiole. Flowers are bright red, arranged in long terminal spikes. The calyx ribs are covered with stipitate, bifarious and subsessile gland. Corolla tube is slender and four times as long as the calyx. The stout roots are cylindrical, irregularly bent, light yellowish brown with smooth surface having short transverse shallow fissures at the regions of the bents. A light yellowish juice excudes from the cut surface. A healthy plant may produce 18-20 stout roots (Warrier et al, 1995).

The chemical constituents include plumbagin and sitosterol glucoside. Clinical trials have demonstrated that plumbagin oil from P. indica is useful in common wart (Satyavati et al, 1987). The roots are acrid, astringent, thermogenic, anthelmintic, constipating, expectorant, antiinflammmatory, abortifacient, alterant, anti-periodic, carminative, digestive, sudorific, narcotic, gastric, nervous stimulant and rejuvenating. Root is a powerful sialogogue and vesicant.

2. P. zeylanica Linn.

Eng:White flowered Leadwort; San:Chitraka;

Hin, Ben:Chitarak, Chitra; Mal:Vellakotuveli

Tam: Sittragam, Chittiramoolam;

Kan: Vahini; Mar: Chitraka;

Tel: Chitramulam

White flowered Leadwort or Chitarak is found wild in peninsular India and mostly in West Bengal. Root is used externally in leprosy and other skin diseases or obstinate character, aphthae, abscesses, influenza, piles and anasarca. Juice is used externally in scabies and ulcers. One of the important preparations of Chitrak is “Yograjguggal”, prescribed for arthritis, rheumatism, etc. The other well known preparations are “Chitrak Adivati” and “ Chitraka Haritaki”. In Unani system it is an ingredient of “Aqaruva-i- Kabir”, “Hab Ashkhar”, “Ma’jun Baladur”, “Ma’jun Raig Mahi”, etc. It is a branched undershrub. Roots are long and tuberous. Stem is striate. Leaves are simple, alternate, short petioled, ovate or ovate-oblong, acute with entire or wavy margin, 7x3.8cm and glabrous. Flowers are white, arranged in terminal spikes. Calyx is tubular, glandular-hairy. Corolla tube is slender; limb rotate and 5 lobbed. Stamens are 5 on a disc. Style is slender with 5 stigmatic branches. Fruit is membranous capsule enclosed within the persistent calyx.

The roots of P. zeylanica have been exhaustively studied and naphthaquinones have been isolated, namely, plumbagin, 3-chlroplumbagin, droserone (Sidhu et al, 1971; Padhye et al, 1973), 3,3’-biplumbagin(Chitranone), zeylanone and iso-zeylanone and a coumarin, elliptinone (Sankaram et al, 1976, 1979). It also contains 1,2(3)-tetrahydro-3,3’-biplumbagin and plumbazeylanone. The leaf is antirheumatic. Root is appetiser, sudorific, relieves pain, vasicant, diuretic, caustic, antidiarrhoeal and expellent of phlegmatic tumours. Root is uterine stimulant. Root and fruits have antiimplantation activity. Plumbagin induces antiimplantation, has abortifacient and antiovulatory activity and causes selective testicular lesions in dogs. It is also a mitotic inhibitor. In lower concentration it behaves like a spindle, poison but in higher concentration it exhibits radiomimetic, nucleotoxic and cyclotoxic effects. It also has antibacterial, antifungal and anticoagulant activities and shows antagonism to amphetamine hyperactivity in mice.

3. P. auriculata Lam. syn. P. capensis

Eng: Blue flowered Leadwort;

Mal: Neelakotuveli

The blue flowered Leadwort is often grown in gardens throughout India (Moos, 1976; Chunekar, 1982; Sharma, 1983). It is a native of Cape Province in South Africa. It is a constituent of many Ayurvedic drugs (KAU, 1991). The plant is a subshrub growing to a height of 1-1.5m. Leaves are elliptic to obovate, 3-4 x 1.5-2cm. Inflorescence is a raceme of length 3-4cm. Corolla is blue to violet. Stamens are 5 in number. Flowers and fruits may be upto 12 in number (Matthew, 1995).

Agrotechnology: The plant is grown in tropical to subtropical ecosystems. Warm humid tropical climate is most suited. They come up well in almost all types of deep and well drained soils. It is propagated vegetatively by stem cuttings. Three stem cuttings of size 15cm long are planted in polybags of size 14x10cm. IAA and IBA treatments will improve rooting of cuttings. The land is to be ploughed well. About 4 tonnes of FYM are to be applied, mixed thoroughly and seed bed of size 50cm breadth, 1.5cm height and convenient length are to be prepared. On these beds pits are taken at a distance of 25cm and the rooted plants are transplanted from the polybags. Regular irrigation and weeding are to be carried out. In the second year with the onset of monsoon, seedbeds are again refreshed after adding about 4 tonnes of FYM. At the end of second year tubers are collected. Care should be taken to wear gloves, else the chemical plumbagin present in the roots will cause burning sensation. The collected tubers are washed, tied into bundles and marketed. Plumbago yields about 7-10t tubers/ha with good management (Prasad et al, 1997).... leadwort

Benth.

Synonym: Ougeinia oojeinensis (Roxb.) Hochr.

Family: Papilionaceae; Fabaceae.

Habitat: Outer Himalayas and sub-Himalayan tract from Jammu to Bhutan up to an altitude of 1,500 m, and extending through the whole of northern and central India into the greater part of Deccan Peninsula.

English: Chariot tree, Punjab Kino.

Ayurvedic: Tinishaa, Tinisha, Syandana, Nemi, Sarvasaara, Ashmagarbhaka, Vajjala, Chitrakrt.

Siddha/Tamil: Narivengai.

Folk: Saanan.

Action: Bark—febrifuge, anti- diarrhoeal, spasmolytic.

The leaves and heartwood contained iso-flavonoids—dalbergion, hemofer- ritin and urgenin. Leaves, in addition, contained flavonoids—querce- tin, kaempferol and leucopelargonidin. Stem bark gave triterpenes, lupeol and betulin.... ougeinia dalbergioides

Linn.

Synonym: P. rosea Linn.

Family: Plumbaginaceae.

Habitat: Indigenous to Sikkim and khasi hills, grown in Indian gardens.

English: Rose-coloured Leadwort.

Ayurvedic: Rakta-chitraka (red- flowered var.).

Siddha/Tamil: Chittramoolam.

Action: See P. zeylanica. P indica is preferred in West Bengal and Kerala. Both P. indica and P. zeylanica contain about 0.9 plumbagin.... plumbago indica

Linn.

Family: Plumbaginaceae.

Habitat: Cultivated in gardens throughout India; also found wild in Peninsular India.

English: Ceylon Leadwort, Leadwort.

Ayurvedic: Chitraka, Agni, Vahni, Jvalanaakhya, Krshaanu, Hutaasha, Dahana, Sikhi.

Unani: Sheetraj Hindi. Siddha/Tamil: Chittramoolam.

Action: Root—intestinal flora normalizer, stimulates digestive processes; used for dyspepsia. Root paste is applied in order to open abscesses; a paste prepared with milk, vinegar or salt and water, is used externally in leprosy and other obstinate skin diseases. A cold infusion is used for influenza and black-water fever.

Key application: In sprue, malabsorption syndrome, piles and inflammatory diseases of ano-rectum. (The Ayurvedic Pharmacopoeia of India.)

The root yielded naphthoquinone derivatives, plumbagin being the most important active principle.

The root extract, after processing for plumbagin enhancement, has been used in a number of drug formulations for liver ailments. Experimentally, plumbagin prevented the accumulation of triglycerides in liver and aorta and regressed atheromatous plaques and abdominal aorta. The chloroform extract of the root showed significant activity against pencillin-resistant (also non-pencillin resistant) strains of Neisseria gonorrhoea. (The root is used for treating sexually transmitted diseases in traditional Indian medicine.)

In Siddha medicine, in Tamil Nadu, the plant is an ingredient in a number of drug formulations for treating cancers of the uterus, breast, lungs and oral cavity, in addition to haemorrhoids.

Plumbagin is abortifacient, antiovu- latory; causes selective testicular lesions in dogs; in lower doses it behaves like a spindle poison, in higher concentration exhibits radiomimetic nu- cleotoxic and cytotoxic effects.

Dosage: Detoxified root—1-2 g powder. (API, Vol. I.)... plumbago zeylanica

Linn.

Family: Euphorbiaceae.

Habitat: Cultivated chiefly in Andhra Pradesh, Maharashtra, Karnataka, and Orissa.

English: Castor seed.

Ayurvedic: Eranda, Chitra- bija, Triputi; Tribija, Vaataari, Chanchu, Manda, Uruvaka, Gandharva-hastaa, Panchaan- gula, Vardhamaana, Uttaanpatraka, Vyaaghrapuchha, Chitraa.

Unani: Bedanjeer, Arand.

Siddha/Tamil: Ammanakku.

Action: Oil from seeds and young leaf—purgative. Oil is used in dermatosis and eczema. Leaves— used as poultice to extract the worm.

Root—a decoction is administered for lumbago and allied complaints.

Bark—purgative.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the decoction of the dried, mature root in rheumatism, pain in the urinary bladder, lumbago, diseases of the abdomen and inflammations; fresh leaf in helminthiasis, dysu- ria, arthritis, pain in the urinary bladder, dysuria, abscesses; dried seed powder in constipation, rheumatism, diseases of the liver and spleen, piles, lumbago, sciatica.

The root extract exhibited significant anti-inflammatory activity against carrageenan-, bradykinin-, 5-HT-and dextran-induced rat hind paw oedema. N-Demethylricinine showed dose-dependent anticholestatic and hepato- protective activities in rats.

Castor oil, derived from the seeds, is a well-known purgative (dose 520 ml).

Castor seed contains toxic components (2.8-3.0% on whole seed; about 10% in the flour) which are highly poisonous to human beings and animals. The principal toxic substance is the albumin, ricin. Allergens and a feebly toxic alkaloid ricinine is also present. An ulcerative factor in the seed is reported. Like other toxalbumins, ricin agglutinizes the mammalian red bleed corpuscles. (Ricin loses its toxicity and antigenic action on treatment with potassium permanganate.)

Castor oil consists principally of ri- cinoleic acid. Stearic, oleic, linoleic and dihydroxystearic acids are present in small amounts. The strong laxative property of castor oil is reported due to the local irritant action caused in the intestines by ricinoleic acid formed by hydrolysis under the influence of lipolytic enzymes. (The oil should not be used with fat-soluble vermifuge, it may increase its absorption and toxic- ity.)

Dosage: Root—20-30 g for decoction. (API, Vol. I.) Leaf—10- 20 ml juice; 2-5 g powder; seed— 0.5-3 g powder. (API, Vol. III.)... ricinus communis

Desv.

Synonym: Hedysarum pictum Jacq.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India, in dry grasslands. Ayurvedic: Prishniparni, Prithak- parni, Simhapushpi, Kalashi, Dhaavani, Guhaa, Chitraparni.

Siddha/Tamil: Oripai.

Action: Root—prescribed for cough, chills and fevers. Leaves—antiseptic, used for urinary discharges and genitourinary infections.

The Ayurvedic Pharmacopoeia of India recommends a decoction of whole plant in alcoholism, insanity, psychosis; cough, bronchitis, dyspnoea; diseases due to vitiated blood; gout; bleeding piles; blood dysentery, acute diarrhoea.

The plant is credited with fracture- healing properties. Its total extract exhibits better and quicker healing of fractures in experimental animals due to early accumulation of phosphorus and more deposition of calcium.

Dosage: Whole plant—20-50 g powder for decoction. (API, Vol. IV.)... uraria picta