Habitat: Cultivated in Khasi hills and Cachar. Also in Guntur (Andhra Pradesh). Found in semiwild state in the Naga and Khasi hills.
English: Citrus dulcis, Sour Orange, Sweet Orange.Folk: Khattaa.Siddha/Tamil: Mallikanarangi.Action: Peel—laxative, feeble stomachic, emmenagogue. Leaves— prescribed in the treatment of arthritis and bronchitis. Flowers— aqueous extract is employed in scurvy, fever, inflammation, nervous and hysterical cases. Fruit— a decoction is used to recover from cachexia left by intermittent fever and in cases of enlarged spleen. Dried rind—used in atonic dyspepsia.
Key application: Cut peel—in loss of appetite and dyspeptic ailments. (German Commission E.). As a bitter tonic. (British Pharmacopoeia.)The main constituents of the peel include the alkaloid synephrine and N- methyltyramine. Synephrine, an alpha 1-adrenergic agonist, stimulates a rise in blood pressure through vasoconstriction. N-methyltyramine also raises blood pressure.The root gave xanthyletin. The essential oil exhibits antifun- gal activity, it was found effective in treatment-resistant fungal skin diseases. (Expanded Commission E Monographs.)Commercially available Citrus vul- garis (bitter orange) extracts are often promoted for weight loss due to purported thermogenic effects. In animal models, synephrine causes weight loss, but also increases cardiovascular toxic- ity. (Natural Medicines Comprehensive Database, 2007.)