Any disorder affecting the coagulability of blood (see COAGULATION). Among acute conditions precipitating the disorder are ABRUPTIO PLACENTA, HAEMOLYSIS following blood transfusions, infection with gram-negative bacteria (see GRAM’S STAIN), HEAT STROKE, SHOCK and snakebite. Chronic disorders linked with coagulopathy are septic ABORTION, TOXAEMIA of pregnancy, certain cancers and LEUKAEMIA.