Combinations, formulae Health Dictionary

Combinations, Formulae: From 1 Different Sources


 In the evolution of herbal medicine it was discovered that some remedies have affinities and assist others in therapeutic action. An older generation of herbalists learnt how to ‘blend’ herbs according to their properties. Although empiric, such intelligent observation over centuries has developed into lore handed down as traditional medicine.

Use of herbs in combination enhances activity of the mild ones and modifies effects of the strong. Volatile properties of one may be kept in balance by opposing alkaloids, glycosides, etc.

Present practice views with disfavour the combination of several remedies, approval being given to a maximum of no more than four plant substances.

Herbs may be combined in equal parts or in specific proportions; i.e. Elder 4, Ladies’ Mantle 3 and Pulsatilla 1: represent Elder 4 parts, Ladies’ Mantle 3 parts and Pulsatilla 1 part.

The object of combining medicines is (a) to augment, correct or modify the action of a remedy, (b) to obtain a joint operation of two or more remedies, (c) to obtain a new medicine and (d) to afford a suitable form for administration.

“A combination of similar remedies will produce a more certain, speedy and considerable effect than an equivalent dose of any single one.” (Fordyce) Some herbs used singly may be of little use, their true value lying in a correct combination. Referred to as polypharmacy where a number of remedies are used in one prescription. 

Health Source: Bartrams Encyclopedia of Herbal Medicine
Author: Health Encyclopedia

Formulary

A list of formulae used as drugs and other medical preparations. The British National Formulary is an authoritative six-monthly publication containing information and advice on medicines and drugs. Published jointly by the British Medical Association and the Royal Pharmaceutical Society of Great Britain, with input from the Department of Health, it is distributed to all NHS doctors by the government. In 2005 a BNF for children was published and many hospitals and general practices produce formularies for use by doctors working in those facilities.... formulary

Braille

A system of printing or writing devised for blind people. Developed by the Frenchman Louis Braille, the system is based on six raised dots which can be organised in di?erent combinations within two grades. Each system in Grade I represents an individual letter or punctuation mark. Grade II’s symbols represent common combinations of letters or individual words. Braille is accepted for all written languages, mathematics, science and music, with Grade II the more popular type.... braille

Cough

A natural re?ex reaction to irritation of the AIR PASSAGES and LUNGS. Air is drawn into the air passages with the GLOTTIS wide open. The inhaled air is blown out against the closed glottis, which, as the pressure builds up, suddenly opens, expelling the air – at an estimated speed of 960 kilometres (600 miles) an hour. This explosive exhalation expels harmful substances from the respiratory tract. Causes of coughing include infection – for example, BRONCHITIS or PNEUMONIA; in?ammation of the respiratory tract associated with ASTHMA; and exposure to irritant agents such as chemical fumes or smoke (see also CROUP).

The explosive nature of coughing results in a spray of droplets into the surrounding air and, if these are infective, hastens the spread of colds (see COLD, COMMON) and INFLUENZA. Coughing is, however, a useful reaction, helping the body to rid itself of excess phlegm (mucus) and other irritants. The physical e?ort of persistent coughing, however, can itself increase irritation of the air passages and cause distress to the patient. Severe and protracted coughing may, rarely, fracture a rib or cause PNEUMOTHORAX. Coughs can be classi?ed as productive – when phlegm is present – and dry, when little or no mucus is produced.

Most coughs are the result of common-cold infections but a persistent cough with yellow or green sputum is indicative of infection, usually bronchitis, and sufferers should seek medical advice as medication and postural drainage (see PHYSIOTHERAPY) may be needed. PLEURISY, pneumonia and lung CANCER are all likely to cause persistent coughing, sometimes associated with chest pain, so it is clearly important for people with a persistent cough, usually accompanied by malaise or PYREXIA, to seek medical advice.

Treatment Treatment of coughs requires treatment of the underlying cause. In the case of colds, symptomatic treatment with simple remedies such as inhalation of steam is usually as e?ective as any medicines, though ANALGESICS or ANTIPYRETICS may be helpful if pain or a raised temperature are among the symptoms. Many over-the-counter preparations are available and can help people cope with the symptoms. Preparations may contain an analgesic, antipyretic, decongestant or antihistamine in varying combinations. Cough medicines are generally regarded by doctors as ine?ective unless used in doses so large they are likely to cause sedation as they act on the part of the brain that controls the cough re?ex.

Cough suppressants may contain CODEINE, DEXTROMETHORPHAN, PHOLCODINE and sedating ANTIHISTAMINE DRUGS. Expectorant preparations usually contain subemetic doses of substances such as ammonium chloride, IPECACUANHA, and SQUILL (none of which have proven worth), while demulcent preparations contain soothing, harmless agents such as syrup or glycerol.

A list of systemic cough and decongestant preparations on sale to the public, together with their key ingredients, appears in the British National Formulary.... cough

Hypertension

Means high BLOOD PRESSURE (raised pressure of the circulating blood), but since there is a wide range of ‘normal’ blood pressure in the population, a precise level of pressure above which an individual is deemed hypertensive is arbitrary. (A healthy young adult would be expected to have a systolic pressure of around 120 mm Hg and a diastolic of 80 mm Hg, recorded as 120/80.) Hypertension is not a disease as such but a quantitative deviation from the norm. A person with a pressure higher than the average for his or her age group is usually symptomless – although sometimes such people may develop headaches. The identi?cation of people with hypertension is important because it is a signal that they will be more likely to have a STROKE or myocardial infarct (coronary thrombosis or heart attack) than someone whose pressure is in the ‘normal’ range. Preventive steps can then be taken to lessen the likelihood of their developing these potentially life-threatening conditions.

Blood pressure is measured using two values. The systolic pressure – the greater of the two – represents the pressure when blood is pumped from the left VENTRICLE of the heart into the AORTA. The diastolic pressure is the measurement when both ventricles relax between beats. The pressures are measured in millimetres (mm) of mercury (Hg). Despite the grey area between normal and raised blood pressure, the World Health Organisation (WHO) has de?ned hypertension as a blood pressure consistently greater than 160 mm Hg (systolic) and 95 mm Hg (diastolic). Young children have readings well below these, but blood pressure rises with age and a healthy person may well live symptom free with a systolic pressure above the WHO ?gure. A useful working de?nition of hypertension is the ?gure at which the bene?ts of treating the condition outweigh the risks and costs of the treatment.

Between 10 and 20 per cent of the adult population in the UK has hypertension, with more men than women affected. Incidence is highest in the middle-aged and elderly. Because most people with hypertension are symptomless, the condition is often ?rst identi?ed during a routine medical examination, otherwise a diagnosis is usually made when complications occur. Many people’s blood pressure rises when they are anxious or after exercise, so if someone’s pressure is above normal at the ?rst testing, it should be taken again after, say, 10 minutes’ rest, by which time the reading should have settled to the person’s regular level. BP measurements should then be taken on two subsequent occasions. If the pressure is still high, the cause needs to be determined: this is done using a combination of personal and family histories (hypertension can run in families), a physical examination and investigations, including an ECG and blood tests for renal disease.

Over 90 per cent of hypertensive people have no immediately identi?able cause for their condition. They are described as having essential hypertension. In those patients with an identi?able cause, the hypertension is described as secondary. Among the causes of secondary hypertension are:

Lifestyle factors such as smoking, alcohol, stress, excessive dietary salt and obesity.

Diseases of the KIDNEYS.

Pregnancy (ECLAMPSIA).

Various ENDOCRINE disorders – for example, PHAEOCHROMOCYTOMA, CUSHING’S DISEASE, ACROMEGALY, thyrotoxicosis (see under THYROID GLAND, DISEASES OF).

COARCTATION OF THE AORTA.

Drugs – for example, oestrogen-containing oral contraceptives (see under CONTRACEPTION), ANABOLIC STEROIDS, CORTICOSTEROIDS, NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS).

Treatment People with severe hypertension may need prompt admission to hospital for urgent investigation and treatment. Those with a mild to moderate rise in blood pressure for which no cause is identi?able should be advised to change their lifestyle: smokers should stop the habit, and those with high alcohol consumption should greatly reduce or stop their drinking. Obese people should reduce their food consumption, especially of animal fats, and take more exercise. Everyone with hypertension should follow a low-salt diet and take regular exercise. Patients should also be taught how to relax, which helps to reduce blood pressure and, if they have a stressful life, working patterns should be modi?ed if possible. If these lifestyle changes do not reduce a person’s blood pressure su?ciently, drugs to achieve this will be needed. A wide range of anti-hypertensive drugs are available on prescription.

A ?rst-line treatment is one of the THIAZIDES, e?ective at a low dosage and especially useful in the elderly. Beta blockers (see BETAADRENOCEPTOR-BLOCKING DRUGS), such as oxprenolol, acebutol or atenolol, are also ?rst-line treatments. ACE inhibitors (see ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITORS) and CALCIUM-CHANNEL BLOCKERS can be used if the ?rst-line choices are not e?ective. The drug treatment of hypertension is complex, and sometimes various drugs or combinations of drugs have to be tried to ?nd what regimen is e?ective and suits the patient. Mild to moderate hypertension can usually be treated in general practice, but patients who do not respond or have complications will normally require specialist advice. Patients on anti-hypertensive treatments require regular monitoring, and, as treatment may be necessary for several years, particular attention should be paid to identifying sideeffects. Nevertheless, e?ective treatment of hypertension does enable affected individuals to live longer and more comfortable lives than would otherwise be the case. Older people with moderately raised blood pressure are often able to live with the condition, and treatment with anti-hypertensive drugs may produce symptoms of HYPOTENSION.

In summary, hypertension is a complex disorder, with di?erent patients responding di?erently to treatment. So the condition sometimes requires careful assessment before the most e?ective therapy for a particular individual is identi?ed, and continued monitoring of patients with the disorder is advisable.

Complications Untreated hypertension may eventually result in serious complications. People with high blood pressure have blood vessels with thickened, less ?exible walls, a narrowed LUMEN and convoluted shape. Sometimes arteries become rigid. ANEURYSM may develop and widespread ATHEROMA (fat deposits) is apparent in the arterial linings. Such changes adversely affect the blood supply to body tissues and organs and so damage their functioning. Patients suffer STROKE (haemorrhage from or thrombosis in the arteries of the BRAIN) and heart attacks (coronary thrombosis

– see HEART, DISEASES OF). Those with hypertension may suffer damage to the retina of the EYE and to the OPTIC DISC. Indeed, the diagnosis of hypertension is sometimes made during a routine eye test, when the doctor or optician notices changes in the retinal arteries or optic disc. Kidney function is often affected, with patients excreting protein and excessive salt in their urine. Occasionally someone with persistent hypertension may suffer an acceleration of damage to the blood vessels – a condition described as ‘malignant’ hypertension, and one requiring urgent hospital treatment.

Hypertension is a potentially dangerous disease because it develops into a cycle of self-perpetuating damage. Faulty blood vessels lead to high blood pressure which in turn aggravates the damage in the vessels and thus in the tissues and organs they supply with blood; this further raises the affected individual’s blood pressure and the pathological cycle continues.... hypertension

Menopause

This is the term applied to the cessation of MENSTRUATION at the end of reproductive life. Usually it occurs between the ages of 45 and 50, although it may occur before the age of 30 or after the age of 50. It can be a psychologically disturbing experience which is quite often accompanied by physical manifestations. These include hot ?ushes, tiredness, irritability, lack of concentration, palpitations, aching joints and vaginal irritation. There may also be loss of libido (sex drive). Most women can and do live happy, active lives through the menopause, the length of which varies considerably.

One of the major problems of the menopause which does not give rise to symptoms until many years later is osteoporosis (see BONE, DISORDERS OF). After the menopause, 1 per cent of the bone is lost per annum to the end of life. This is a factor in the frequency of fractures of the femur in elderly women as a result of osetoporosis, but it can be prevented by hormone replacement therapy (see below).

Hormone replacement therapy (HRT) This term has become synonymous with the scienti?cally correct term ‘OESTROGENS replacement therapy’ to signify the treatment of menopausal symptoms and signs with oestrogens, now usually combined with PROGESTOGEN. Oestrogen and combined treatment relieve the short-term symptoms such as hot ?ushes, sweats and vaginal dryness. Atrophic vaginitis and vulvitis (shrinking of the tissues of VULVA and VAGINA due to fall in natural oestrogen levels) also usually respond to treatment with oestrogens.

Cyclical therapy is necessary to avoid abnormal bleeding in women who have reached the menopause. If oestrogens are given alone, there is an increased risk of endometrial hyperplasia (overgrowth of the ENDOMETRIUM) which may lead to endometrial cancer, so these are restricted to women who have had a hysterectomy and are no longer at risk. Other women can be given oestrogen-progestogen combinations.

There is good evidence that oestrogen alone or in combination can prevent the bone-loss associated with the menopause by reducing the demineralisation of bone which normally occurs after the menopause; and, if it is started early and continued for years, it may prevent the development of osteoporosis. Oestrogen is far more e?ective than calcium supplements and has been shown greatly to reduce fractures affecting the spine, wrists and legs after the age of 50.

However, HRT is no longer licensed for ?rst-line treatment to prevent osteoporosis, as increased risk of stroke, breast cancer and coronary heart disease cannot justify treatment for long periods – unless the woman has severe menopausal symptoms. HRT is recommended for short-term use only in menopausal women whose lives are inconvenienced by vasomotor instability (severe ?ushes, etc.) or vaginal atrophy, although the latter may respond to local oestrogen treatment – creams or pessaries. In terms of oestrogenic activity, natural oestrogen such as oestradiol, oestrone and oestriol are more appropriate for HRT than synthetic oestrogens like ethinyloestradiol, mestranol and diethylstilboestrol.

Many experts believe that controversy surrounding the risks and bene?ts of HRT have been settled by a large randomised trial (the Women’s Health Initiative), published in 2003, which showed that combined treatment increases the risk of breast tumours, stroke and coronary heart disease (in the ?rst year). Oestrogen alone (given to women who have had a hysterectomy) also increases the risk of stroke. Five years of combined treatment may double the risk of breast cancer, and the heart-disease risk is nearly doubled during the ?rst year of use. This is in spite of the bene?cial effects of HRT on blood lipids. However, there are others who consider that di?erent dose combinations of di?erent hormones may one day prove bene?cial, so research continues.

HRT can also provoke minor adverse effects such as breast tenderness, ?uid retention, leg cramps and nausea. The risk of abnormal blood clotting means that HRT is not normally recommended for women who smoke heavily or have had THROMBOSIS, severe HYPERTENSION, stroke or liver disease. HRT has, however, brought symptomatic bene?ts to many menopausal women, who can then justify taking the other increased risks – only fully understood since the large trial results were published.

As the evidence stands at present, careful consideration of each woman’s medical history and the severity of her menopausal symptoms is necessary in deciding what combination of drugs should be given and for how long. In general, the indications should be severe menopausal symptoms that can be controlled by the lowest dose for the shortest time. Using HRT to alleviate mild symptoms, or to prevent future bone loss, is probably of insu?cient bene?t to counter the other risks described above.... menopause

Aids/hiv

Acquired Immune De?ciency Syndrome (AIDS) is the clinical manifestation of infection with Human Immunode?ciency Virus (HIV). HIV belongs to the retroviruses, which in turn belong to the lentiviruses (characterised by slow onset of disease). There are two main HIV strains: HIV-1, by far the commonest; and HIV-2, which is prevalent in Western Africa (including Ivory Coast, Gambia, Mali, Nigeria and Sierra Leone). HIV attacks the human immune system (see IMMUNITY) so that the infected person becomes susceptible to opportunistic infections, such as TUBERCULOSIS, PNEUMONIA, DIARRHOEA, MENINGITIS and tumours such as KAPOSI’S SARCOMA. AIDS is thus the disease syndrome associated with advanced HIV infection.

Both HIV-1 and HIV-2 are predominantly sexually transmitted and both are associated with secondary opportunistic infections. However, HIV-2 seems to result in slower damage to the immune system. HIV-1 is known to mutate rapidly and has given rise to other subtypes.

HIV is thought to have occurred in humans in the 1950s, but whether or not it infected humans from another primate species is uncertain. It became widespread in the 1970s but its latency in causing symptoms meant that the epidemic was not noticed until the following decade. Although it is a sexually transmitted disease, it can also be transmitted by intravenous drug use (through sharing an infected needle), blood transfusions with infected blood (hence the importance of e?ective national blood-screening programmes), organ donation, and occupationally (see health-care workers, below). Babies born of HIV-positive mothers can be infected before or during birth, or through breast feeding.

Although HIV is most likely to occur in blood, semen or vaginal ?uid, it has been found in saliva and tears (but not sweat); however, there is no evidence that the virus can be transmitted from these two body ?uids. There is also no evidence that HIV can be transmitted by biting insects (such as mosquitoes). HIV does not survive well in the environment and is rapidly destroyed through drying.

Prevalence At the end of 2003 an estimated 42 million people globally were infected with HIV – up from 40 million two years earlier. About one-third of those with HIV/AIDS are aged 15–24 and most are unaware that they are carrying the virus. During 2003 it is estimated that 5 million adults and children worldwide were newly infected with HIV, and that 3 million adults and children died. In Africa in 2003,

3.4 million people were newly infected and 2.3 million died, with more than 28 million carrying the virus. HIV/AIDS was the leading cause of death in sub-Saharan Africa where over half of the infections were in women and 90 per cent of cases resulted from heterosexual sex. In some southern African countries, one in three pregnant women had HIV.

In Asia and the Paci?c there were 1.2 million new infections and 435,000 deaths. The area with the fastest-growing epidemic is Eastern Europe, especially the Russian Federation where in 2002 around a million people had HIV and there were an estimated 250,000 new infections, with intravenous drug use a key contributor to this ?gure. Seventy-?ve per cent of cases occurred in men, with male-to-male sexual transmission an important cause of infection, though heterosexual activity is a rising cause of infection.

At the end of 2002 the UK had an estimated 55,900 HIV-infected adults aged between 15 and 59. More than 3,600 individuals were newly diagnosed with the infection in 2000, the highest annual ?gure since the epidemic started

– in 1998 the ?gure was 2,817 and in 1999 just over 3,000 (Department of Health and Communicable Disease Surveillance Centre). The incidence of AIDS in the UK has declined sharply since the introduction of highly active antiretroviral therapy (HAART) and HIV-related deaths have also fallen: in 2002 there were 777 reported new AIDS cases and 395 deaths, compared with 1,769 and 1,719 respectively in 1995. (Sources: UNAIDS and WHO, AIDS Epidemic Update, December 2001; Public Health Laboratory Services AIDS and STD Centre Communicable Disease Surveillance and Scottish Centre for Infection and Environmental Health, Quarterly Surveillance Tables.)

Poverty is strongly linked to the spread of AIDS, for various reasons including lack of health education; lack of e?ective public-health awareness; women having little control over sexual behaviour and contraception; and, by comparison with the developed world, little or no access to antiretroviral drugs.

Pathogenesis The cellular target of HIV infection is a subset of white blood cells called T-lymphocytes (see LYMPHOCYTE) which carry the CD4 surface receptor. These so-called ‘helper T-cells’ are vital to the function of cell-mediated immunity. Infection of these cells leads to their destruction (HIV replicates at an enormous rate – 109) and over the course of several years the body is unable to generate suf?cient new cells to keep pace. This leads to progressive destruction of the body’s immune capabilities, evidenced clinically by the development of opportunistic infection and unusual tumours.

Monitoring of clinical progression It is possible to measure the number of viral particles present in the plasma. This gives an accurate guide to the likely progression rate, which will be slow in those individuals with fewer than 10,000 particles per ml of plasma but progressively more rapid above this ?gure. The main clinical monitoring of the immune system is through the numbers of CD4 lymphocytes in the blood. The normal count is around 850 cells per ml and, without treatment, eventual progression to AIDS is likely in those individuals whose CD4 count falls below 500 per ml. Opportunistic infections occur most frequently when the count falls below 200 per ml: most such infections are treatable, and death is only likely when the CD4 count falls below 50 cells per ml when infection is developed with organisms that are di?cult to treat because of their low intrinsic virulence.

Simple, cheap and highly accurate tests are available to detect HIV antibodies in the serum. These normally occur within three months of infection and remain the cornerstone of the diagnosis.

Clinical features Most infected individuals have a viral illness some three weeks after contact with HIV. The clinical features are often non-speci?c and remain undiagnosed but include a ?ne red rash, large lymph nodes, an in?uenza-like illness, cerebral involvement and sometimes the development of opportunistic infections. The antibody test may be negative at this stage but there are usually high levels of virus particles in the blood. The antibody test is virtually always positive within three months of infection. HIV infection is often subsequently asymptomatic for a period of ten years or more, although in most patients progressive immune destruction is occurring during this time and a variety of minor opportunistic infections such as HERPES ZOSTER or oral thrush (see CANDIDA) do occur. In addition, generalised LYMPHADENOPATHY is present in a third of patients and some suffer from severe malaise, weight loss, night sweats, mild fever, ANAEMIA or easy bruising due to THROMBOCYTOPENIA.

The presentation of opportunistic infection is highly variable but usually involves either the CENTRAL NERVOUS SYSTEM, the gastrointestinal tract or the LUNGS. Patients may present with a sudden onset of a neurological de?cit or EPILEPSY due to a sudden onset of a STROKE-like syndrome, or epilepsy due to a space-occupying lesion in the brain – most commonly TOXOPLASMOSIS. In late disease, HIV infection of the central nervous system itself may produce progressive memory loss, impaired concentration and mental slowness called AIDS DEMENTIA. A wide variety of opportunistic PROTOZOA or viruses produces DYSPHAGIA, DIARRHOEA and wasting. In the respiratory system the commonest opportunistic infection associated with AIDS, pneumonia, produces severe shortness of breath and sometimes CYANOSIS, usually with a striking lack of clinical signs in the chest.

In very late HIV infection, when the CD4 count has fallen below 50 cells per ml, infection with CYTOMEGALOVIRUS may produce progressive retinal necrosis (see EYE, DISORDERS OF) which will lead to blindness if untreated, as well as a variety of gastrointestinal symptoms. At this stage, infection with atypical mycobacteria is also common, producing severe anaemia, wasting and fevers. The commonest tumour associated with HIV is Kaposi’s sarcoma which produces purplish skin lesions. This and nonHodgkin’s lymphoma (see LYMPHOMA), which is a hundred times more frequent among HIV-positive individuals than in the general population, are likely to be associated with or caused by opportunistic viral infections.

Prevention There is, as yet, no vaccine to prevent HIV infection. Vaccine development has been hampered

by the large number of new HIV strains generated through frequent mutation and recombination.

because HIV can be transmitted as free virus and in infected cells.

because HIV infects helper T-cells – the very cells involved in the immune response. There are, however, numerous research pro

grammes underway to develop vaccines that are either prophylactic or therapeutic. Vaccine-development strategies have included: recombinant-vector vaccines, in which a live bacterium or virus is genetically modi?ed to carry one or more of the HIV genes; subunit vaccines, consisting of small regions of the HIV genome designed to induce an immune response without infection; modi?ed live HIV, which has had its disease-promoting genes removed; and DNA vaccines – small loops of DNA (plasmids) containing viral genes – that make the host cells produce non-infectious viral proteins which, in turn, trigger an immune response and prime the immune system against future infection with real virus.

In the absence of an e?ective vaccine, preventing exposure remains the chief strategy in reducing the spread of HIV. Used properly, condoms are an extremely e?ective method of preventing exposure to HIV during sexual intercourse and remain the most important public-health approach to countering the further acceleration of the AIDS epidemic. The spermicide nonoxynol-9, which is often included with condoms, is known to kill HIV in vitro; however, its e?ectiveness in preventing HIV infection during intercourse is not known.

Public-health strategies must be focused on avoiding high-risk behaviour and, particularly in developing countries, empowering women to have more control over their lives, both economically and socially. In many of the poorer regions of the world, women are economically dependent on men and refusing sex, or insisting on condom use, even when they know their partners are HIV positive, is not a straightforward option. Poverty also forces many women into the sex industry where they are at greater risk of infection.

Cultural problems in gaining acceptance for universal condom-use by men in some developing countries suggests that other preventive strategies should also be considered. Microbicides used as vaginal sprays or ‘chemical condoms’ have the potential to give women more direct control over their exposure risk, and research is underway to develop suitable products.

Epidemiological studies suggest that male circumcision may o?er some protection against HIV infection, although more research is needed before this can be an established public-health strategy. Globally, about 70 per cent of infected men have acquired the virus through unprotected vaginal sex; in these men, infection is likely to have occurred through the penis with the mucosal epithelia of the inner surface of the foreskin and the frenulum considered the most likely sites for infection. It is suggested that in circumcised men, the glans may become keratinised and thus less likely to facilitate infection. Circumcision may also reduce the risk of lesions caused by other sexually transmitted disease.

Treatment AIDS/HIV treatment can be categorised as speci?c therapies for the individual opportunistic infections – which ultimately cause death – and highly active antiretroviral therapy (HAART) designed to reduce viral load and replication. HAART is also the most e?ective way of preventing opportunistic infections, and has had a signi?cant impact in delaying the onset of AIDS in HIV-positive individuals in developed countries.

Four classes of drugs are currently in use. Nucleoside analogues, including ZIDOVUDINE and DIDANOSINE, interfere with the activity of the unique enzyme of the retrovirus reverse transcriptase which is essential for replication. Nucleotide analogues, such as tenofovir, act in the same way but require no intracellular activation. Non-nucleoside reverse transcriptase inhibitors, such as nevirapine and EFAVIRENZ, act by a di?erent mechanism on the same enzyme. The most potent single agents against HIV are the protease inhibitors, such as lopinavir, which render a unique viral enzyme ineffective. These drugs are used in a variety of combinations in an attempt to reduce the plasma HIV viral load to below detectable limits, which is achieved in approximately 90 per cent of patients who have not previously received therapy. This usually also produces a profound rise in CD4 count. It is likely, however, that such treatments need to be lifelong – and since they are associated with toxicities, long-term adherence is di?cult. Thus the optimum time for treatment intervention remains controversial, with some clinicians believing that this should be governed by the viral load rising above 10,000 copies, and others that it should primarily be designed to prevent the development of opportunistic infections – thus, that initiation of therapy should be guided more by the CD4 count.

It should be noted that the drug regimens have been devised for infection with HIV-1; it is not known how e?ective they are at treating infection with HIV-2.

HIV and pregnancy An HIV-positive woman can transmit the virus to her fetus, with the risk of infection being particularly high during parturition; however, the risk of perinatal HIV transmission can be reduced by antiviral drug therapy. In the UK, HIV testing is available to all women as part of antenatal care. The bene?ts of antenatal HIV testing in countries where antiviral drugs are not available are questionable. An HIV-positive woman might be advised not to breast feed because of the risks of transmitting HIV via breastmilk, but there may be a greater risk associated with not breast feeding at all. Babies in many poor communities are thought to be at high risk of infectious diseases and malnutrition if they are not breast fed and may thus be at greater overall risk of death during infancy.

Counselling Con?dential counselling is an essential part of AIDS management, both in terms of supporting the psychological wellbeing of the individual and in dealing with issues such as family relations, sexual partners and implications for employment (e.g. for health-care workers). Counsellors must be particularly sensitive to culture and lifestyle issues. Counselling is essential both before an HIV test is taken and when the results are revealed.

Health-care workers Health-care workers may be at risk of occupational exposure to HIV, either through undertaking invasive procedures or through accidental exposure to infected blood from a contaminated needle (needlestick injury). Needlestick injuries are frequent in health care – as many as 600,000 to 800,000 are thought to occur annually in the United States. Transmission is much more likely where the worker has been exposed to HIV through a needlestick injury or deep cut with a contaminated instrument than through exposure of mucous membranes to contaminated blood or body ?uids. However, even where exposure occurs through a needlestick injury, the risk of seroconversion is much lower than with a similar exposure to hepatitis C or hepatitis B. A percutaneous exposure to HIV-infected blood in a health-care setting is thought to carry a risk of about one infection per 300 injuries (one in 1,000 for mucous-membrane exposure), compared with one in 30 for hepatitis C, and one in three for hepatitis B (when the source patient is e-antigen positive).

In the event of an injury, health-care workers are advised to report the incident immediately where, depending on a risk assessment, they may be o?ered post-exposure prophylaxis (PEP). They should also wash the contaminated area with soap and water (but without scrubbing) and, if appropriate, encourage bleeding at the site of injury. PEP, using a combination of antiretroviral drugs (in a similar regimen to HAART – see above), is thought to greatly reduce the chances of seroconversion; it should be commenced as soon as possible, preferably within one or two hours of the injury. Although PEP is available, safe systems of work are considered to o?er the greatest protection. Double-gloving (latex gloves remove much of the blood from the surface of the needle during a needlestick), correct use of sharps containers (for used needles and instruments), avoiding the resheathing of used needles, reduction in the number of blood samples taken from a patient, safer-needle devices (such as needles that self-blunt after use) and needleless drug administration are all thought to reduce the risk of exposure to HIV and other blood-borne viruses. Although there have been numerous cases of health-care workers developing HIV through occupational exposure, there is little evidence of health-care workers passing HIV to their patients through normal medical procedures.... aids/hiv

Antibiotics

Antibiotic is the term used to describe any antibacterial agent derived from micro-organisms, although most of them are now prepared synthetically. Such agents destroy or inhibit the growth of other micro-organisms: examples are penicillin, cephalosporin, amino-glycosides, streptomycin, and tetracycline.

Penicillin was the ?rst antibiotic to be discovered and used in the 1940s. The discovery and isolation in 1958 of the penicillin nucleus, 6-amino penicillanic acid (6-PNA), allowed many new penicillins to be synthesised. These are now the largest single group of antibiotics used in clinical medicine. Most staphylococci (see STAPHYLOCOCCUS) have now developed resistance to benzylpenicillin, the early form of the drug, because they produce penicillinases – enzymes which break down the drug. Other types of penicillin such as cloxacillin and ?ucoxacillin are not affected and are used against penicillin-resistant staphylococci.

The cephalosporins are derived from the compound cephalosporin C, which is obtained by fermentation of the mould cephalosporium.

The cephalosporin nucleus 7 amino cephalosporanic (7-ICA) acid has been the basis for the production of the semi-synthetic compounds of the cephalosporin nucleus. The ?rst semi-synthetic cephalosporin, cephalothin, appeared in 1962; it was followed by cephaloridine in 1964. The original cephalosporins had to be given by injection, but more recent preparations can be given by mouth. The newer preparations are less readily destroyed by betalactamases and so they have a much broader spectrum of antibacterial activity. The newer cephalosporins include cephalexin, cefazolin, cephacetrile, cephapirin, cefamandole, cefuroxine, cephrodine, cefodroxil and cefotaxine. Inactivation of beta-lactamase is the basis of bacterial resistance both to the penicillins and to the cephalosporins, so that attempts to prepare these antibiotics with resistance to betalactamase is of great importance. A synthetic inhibitor of beta-lactamase called clavulanic acid has been synthesised; this is used in combination with the penicillins and cephalosporins to prevent resistance. The cephamycins are a new addition to the beta-lactam antibiotics. They are similar in structure to the cephalosporins but are produced, not by fungi, but by actinomycetes.

Overuse and misuse of antibiotics have resulted in many bacteria becoming resistant to them. Hospitals, in particular, have problems with METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA). Combinations of antibiotics are needed to combat resistant strains of bacteria, another example being Mycobacterium tuberculosis.... antibiotics

Bayberry

Myrica cerifera. N.O. Myricaceae.

Synonym: Candleberry, Waxberry, Wax Myrtle.

Habitat: Near the sea in pastures and on stony soils.

Features ? The bark has a white, peeling epidermis covering a hard, reddish-brown layer beneath. It is slightly fibrous on the inner surface, and the fracture is granular. The taste is pungent, astringent and bitter, the odour faintly aromatic.

Part used ? The bark is the only part of the Bayberry shrub now used as a medicine.

Action: A powerful stimulant, astringent and tonic to the alimentary tract.

Bayberry bark is one of the most widely used agents in the herbal practice. It figures in many of the compound powders and is the base of the celebrated composition powder, a prescription of which will be found in the "Herbal Formulae" section of this volume. In cases of coldness of the extremities, chills and influenza, an infusion of 1 ounce of the powdered bark to 1 pint of water is taken warm. This assists circulation and promotes perspiration, especially when combined with Cayenne as in

the formula referred to above.

As an antiseptic the powder is added to poultices for application to ulcers, sores and wounds. It also makes an excellent snuff for nasal catarrh, and an ingredient in tooth powders, for which a prescription is given in the section previously mentioned.

The virtues of Bayberry bark were recognized and used beneficially by the herbalists of many generations ago. Indeed, their enthusiasm for this, as for certain other remedies also extremely efficacious within proper limits, led them to ascribe properties to the bark which it does not possess. Many affections of the uterine system, fistula, and even cancer were said to yield to its influence.

Even in these cases, however, Bayberry bark certainly did less harm than many of the methods employed by the more orthodox practitioners of that time !... bayberry

Diabetes Mellitus

Diabetes mellitus is a condition characterised by a raised concentration of glucose in the blood due to a de?ciency in the production and/or action of INSULIN, a pancreatic hormone made in special cells called the islet cells of Langerhans.

Insulin-dependent and non-insulindependent diabetes have a varied pathological pattern and are caused by the interaction of several genetic and environmental factors.

Insulin-dependent diabetes mellitus (IDDM) (juvenile-onset diabetes, type 1 diabetes) describes subjects with a severe de?ciency or absence of insulin production. Insulin therapy is essential to prevent KETOSIS – a disturbance of the body’s acid/base balance and an accumulation of ketones in the tissues. The onset is most commonly during childhood, but can occur at any age. Symptoms are acute and weight loss is common.

Non-insulin-dependent diabetes mellitus (NIDDM) (maturity-onset diabetes, type 2 diabetes) may be further sub-divided into obese and non-obese groups. This type usually occurs after the age of 40 years with an insidious onset. Subjects are often overweight and weight loss is uncommon. Ketosis rarely develops. Insulin production is reduced but not absent.

A new hormone has been identi?ed linking obesity to type 2 diabetes. Called resistin – because of its resistance to insulin – it was ?rst found in mice but has since been identi?ed in humans. Researchers in the United States believe that the hormone may, in part, explain how obesity predisposes people to diabetes. Their hypothesis is that a protein in the body’s fat cells triggers insulin resistance around the body. Other research suggests that type 2 diabetes may now be occurring in obese children; this could indicate that children should be eating a more-balanced diet and taking more exercise.

Diabetes associated with other conditions (a) Due to pancreatic disease – for example, chronic pancreatitis (see PANCREAS, DISORDERS OF); (b) secondary to drugs – for example, GLUCOCORTICOIDS (see PANCREAS, DISORDERS OF); (c) excess hormone production

– for example, growth hormone (ACROMEGALY); (d) insulin receptor abnormalities; (e) genetic syndromes (see GENETIC DISORDERS).

Gestational diabetes Diabetes occurring in pregnancy and resolving afterwards.

Aetiology Insulin-dependent diabetes occurs as a result of autoimmune destruction of beta cells within the PANCREAS. Genetic in?uences are important and individuals with certain HLA tissue types (HLA DR3 and HLA DR4) are more at risk; however, the risks associated with the HLA genes are small. If one parent has IDDM, the risk of a child developing IDDM by the age of 25 years is 1·5–2·5 per cent, and the risk of a sibling of an IDDM subject developing diabetes is about 3 per cent.

Non-insulin-dependent diabetes has no HLA association, but the genetic in?uences are much stronger. The risks of developing diabetes vary with di?erent races. Obesity, decreased exercise and ageing increase the risks of disease development. The risk of a sibling of a NIDDM subject developing NIDDM up to the age of 80 years is 30–40 per cent.

Diet Many NIDDM diabetics may be treated with diet alone. For those subjects who are overweight, weight loss is important, although often unsuccessful. A diet high in complex carbohydrate, high in ?bre, low in fat and aiming towards ideal body weight is prescribed. Subjects taking insulin need to eat at regular intervals in relation to their insulin regime and missing meals may result in hypoglycaemia, a lowering of the amount of glucose in the blood, which if untreated can be fatal (see below).

Oral hypoglycaemics are used in the treatment of non-insulin-dependent diabetes in addition to diet, when diet alone fails to control blood-sugar levels. (a) SULPHONYLUREAS act mainly by increasing the production of insulin;

(b) BIGUANIDES, of which only metformin is available, may be used alone or in addition to sulphonylureas. Metformin’s main actions are to lower the production of glucose by the liver and improve its uptake in the peripheral tissues.

Complications The risks of complications increase with duration of disease.

Diabetic hypoglycaemia occurs when amounts of glucose in the blood become low. This may occur in subjects taking sulphonylureas or insulin. Symptoms usually develop when the glucose concentration falls below 2·5 mmol/l. They may, however, occur at higher concentrations in subjects with persistent hyperglycaemia – an excess of glucose – and at lower levels in subjects with persistent hypo-glycaemia. Symptoms include confusion, hunger and sweating, with coma developing if blood-sugar concentrations remain low. Re?ned sugar followed by complex carbohydrate will return the glucose concentration to normal. If the subject is unable to swallow, glucagon may be given intramuscularly or glucose intravenously, followed by oral carbohydrate, once the subject is able to swallow.

Although it has been shown that careful control of the patient’s metabolism prevents late complications in the small blood vessels, the risk of hypoglycaemia is increased and patients need to be well motivated to keep to their dietary and treatment regime. This regime is also very expensive. All risk factors for the patient’s cardiovascular system – not simply controlling hyperglycaemia – may need to be reduced if late complications to the cardiovascular system are to be avoided.

Diabetes is one of the world’s most serious health problems. Recent projections suggest that the disorder will affect nearly 240 million individuals worldwide by 2010 – double its prevalence in 1994. The incidence of insulin-dependent diabetes is rising in young children; they will be liable to develop late complications.

Although there are complications associated with diabetes, many subjects live normal lives and survive to an old age. People with diabetes or their relatives can obtain advice from Diabetes UK (www.diabetes.org.uk).

Increased risks are present of (a) heart disease, (b) peripheral vascular disease, and (c) cerebrovascular disease.

Diabetic eye disease (a) retinopathy, (b) cataract. Regular examination of the fundus enables any abnormalities developing to be detected and treatment given when appropriate to preserve eyesight.

Nephropathy Subjects with diabetes may develop kidney damage which can result in renal failure.

Neuropathy (a) Symmetrical sensory polyneuropathy; damage to the sensory nerves that commonly presents with tingling, numbness of pain in the feet or hands. (b) Asymmetrical motor diabetic neuropathy, presenting as progressive weakness and wasting of the proximal muscles of legs. (c) Mononeuropathy; individual motor or sensory nerves may be affected. (d) Autonomic neuropathy, which affects the autonomic nervous system, has many presentations including IMPOTENCE, diarrhoea or constipation and postural HYPOTENSION.

Skin lesions There are several skin disorders associated with diabetes, including: (a) necrobiosis lipoidica diabeticorum, characterised by one or more yellow atrophic lesions on the legs;

(b) ulcers, which most commonly occur on the feet due to peripheral vascular disease, neuropathy and infection. Foot care is very important.

Diabetic ketoacidosis occurs when there is insu?cient insulin present to prevent KETONE production. This may occur before the diagnosis of IDDM or when insu?cient insulin is being given. The presence of large amounts of ketones in the urine indicates excess ketone production and treatment should be sought immediately. Coma and death may result if the condition is left untreated.

Symptoms Thirst, POLYURIA, GLYCOSURIA, weight loss despite eating, and recurrent infections (e.g. BALANITIS and infections of the VULVA) are the main symptoms.

However, subjects with non-insulindependent diabetes may have the disease for several years without symptoms, and diagnosis is often made incidentally or when presenting with a complication of the disease.

Treatment of diabetes aims to prevent symptoms, restore carbohydrate metabolism to as near normal as possible, and to minimise complications. Concentration of glucose, fructosamine and glycated haemoglobin in the blood are used to give an indication of blood-glucose control.

Insulin-dependent diabetes requires insulin for treatment. Non-insulin-dependent diabetes may be treated with diet, oral HYPOGLYCAEMIC AGENTS or insulin.

Insulin All insulin is injected – mainly by syringe but sometimes by insulin pump – because it is inactivated by gastrointestinal enzymes. There are three main types of insulin preparation: (a) short action (approximately six hours), with rapid onset; (b) intermediate action (approximately 12 hours); (c) long action, with slow onset and lasting for up to 36 hours. Human, porcine and bovine preparations are available. Much of the insulin now used is prepared by genetic engineering techniques from micro-organisms. There are many regimens of insulin treatment involving di?erent combinations of insulin; regimens vary depending on the requirements of the patients, most of whom administer the insulin themselves. Carbohydrate intake, energy expenditure and the presence of infection are important determinants of insulin requirements on a day-to-day basis.

A new treatment for diabetes, pioneered in Canada and entering its preliminary clinical trials in the UK, is the transplantation of islet cells of Langerhans from a healthy person into a patient with the disorder. If the transplantation is successful, the transplanted cells start producing insulin, thus reducing or eliminating the requirement for regular insulin injections. If successful the trials would be a signi?cant advance in the treatment of diabetes.

Scientists in Israel have developed a drug, Dia Pep 277, which stops the body’s immune system from destroying pancratic ? cells as happens in insulin-dependent diabetes. The drug, given by injection, o?ers the possibility of preventing type 1 diabetes in healthy people at genetic risk of developing the disorder, and of checking its progression in affected individuals whose ? cells are already perishing. Trials of the drug are in progress.... diabetes mellitus

Mental Illness

De?ned simply, this is a disorder of the brain’s processes that makes the sufferer feel or seem ill, and may prevent that person from coping with daily life. Psychiatrists – doctors specialising in diagnosing and treating mental illness – have, however, come up with a range of much more complicated de?nitions over the years.

Psychiatrists like to categorise mental illnesses because mental signs and symptoms do occur together in clusters or syndromes, each tending to respond to certain treatments. The idea that illnesses can be diagnosed simply by recognising their symptom patterns may not seem very scienti?c in these days of high technology. For most common mental illnesses, however, this is the only method of diagnosis; whatever is going wrong in the brain is usually too poorly understood and too subtle to show up in laboratory tests or computed tomography scans of the brain. And symptom-based definitions of mental illnesses are, generally, a lot more meaningful than the vague lay term ‘nervous breakdown’, which is used to cover an attack of anything from AGORAPHOBIA to total inability to function.

There is still a lot to learn about the workings of the brain, but psychiatry has developed plenty of practical knowledge about the probable causes of mental illness, ways of relieving symptoms, and ways of aiding recovery. Most experts now believe that mental illnesses generally arise from di?erent combinations of inherited risk and psychological STRESS, sometimes with additional environmental exposure – for example, viruses, drugs or ALCOHOL.

The range of common mental illnesses includes anxiety states, PHOBIA, DEPRESSION, alcohol and drug problems, the EATING DISORDERS anorexia and bulimia nervosa, MANIC DEPRESSION, SCHIZOPHRENIA, DEMENTIA, and a group of problems related to coping with life that psychiatrists call personality disorders.

Of these mental illnesses, dementia is the best understood. It is an irreversible and fatal form of mental deterioration (starting with forgetfulness and eventually leading to severe failure of all the brain’s functions), caused by rapid death of brain cells and consequent brain shrinkage. Schizophrenia is another serious mental illness which disrupts thought-processes, speech, emotions and perception (how the brain handles signals from the ?ve senses). Manic depression, in which prolonged ‘highs’ of extremely elevated mood and overexcitement alternate with abject misery, has similar effects on the mental processes. In both schizophrenia and manic depression the sufferer loses touch with reality, develops unshakeable but completely unrealistic ideas (delusions), and hallucinates (vividly experiences sensations that are not real, e.g. hears voices when there is nobody there). This triad of symptoms is called psychosis and it is what lay people, through fear and lack of understanding, sometimes call lunacy, madness or insanity.

The other mental illnesses mentioned above are sometimes called neuroses. But the term has become derogatory in ordinary lay language; indeed, many people assume that neuroses are mild disorders that only affect weak people who cannot ‘pull themselves together’, while psychoses are always severe. In reality, psychoses can be brief and reversible and neuroses can cause lifelong disability.

However de?ned and categorised, mental illness is a big public-health problem. In the UK, up to one in ?ve women and around one in seven men have had mental illness. About half a million people in Britain suffer from schizophrenia: it is three times commoner than cancer. And at any one time, up to a tenth of the adult population is ill with depression.

Treatment settings Most people with mental-health problems get the help they need from their own family doctor(s), without ever seeing a psychiatrist. General practictitioners in Britain treat nine out of ten recognised mental-health problems and see around 12 million adults with mental illness each year. Even for the one in ten of these patients referred to psychiatrists, general practitioners usually handle those problems that continue or recur.

Psychiatrists, psychiatric nurses, social workers, psychologists, counsellors and therapists often see patients at local doctors’ surgeries and will do home visits if necessary. Community mental-health centres – like general-practice health centres but catering solely for mental-health problems – o?er another short-cut to psychiatric help. The more traditional, and still more common, route to a psychiatrist for many people, however, is from the general practititioner to a hospital outpatient department.

Specialist psychiatric help In many ways, a visit to a psychiatrist is much like any trip to a hospital doctor – and, indeed, psychiatric clinics are often based in the outpatient departments of general hospitals. First appointments with psychiatrists can last an hour or more because the psychiatrist – and sometimes other members of the team such as nurses, doctors in training, and social workers – need to ask lots of questions and record the whole consultation in a set of con?dential case notes.

Psychiatric assessment usually includes an interview and an examination, and is sometimes backed up by a range of tests. The interview begins with the patient’s history – the personal story that explains how and, to some extent, why help is needed now. Mental-health problems almost invariably develop from a mixture of causes – emotional, social, physical and familial – and it helps psychiatrists to know what the people they see are normally like and what kind of lives they have led. These questions may seem unnecessarily intrusive, but they allow psychiatrists to understand patients’ problems and decide on the best way to help them.

The next stage in assessment is the mental-state examination. This is how psychiatrists examine minds, or at least their current state. Mental-state examination entails asking more questions and using careful observation to assess feelings, thoughts and mental symptoms, as well as the way the mind is working (for example, in terms of memory and concentration). During ?rst consultations psychiatrists usually make diagnoses and explain them. The boundary between a life problem that will clear up spontaneously and a mental illness that needs treatment is sometimes quite blurred; one consultation may be enough to put the problem in perspective and help to solve it.

Further assessment in the clinic may be needed, or some additional tests. Simple blood tests can be done in outpatient clinics but other investigations will mean referral to another department, usually on another day.

Further assessment and tests

PSYCHOLOGICAL TESTS Psychologists work in or alongside the psychiatric team, helping in both assessment and treatment. The range of psychological tests studies memory, intelligence, personality, perception and capability for abstract thinking. PHYSICAL TESTS Blood tests and brain scans may be useful to rule out a physical illness causing psychological symptoms. SOCIAL ASSESSMENT Many patients have social diffculties that can be teased out and helped by a psychiatric social worker. ‘Approved social workers’ have special training in the use of the Mental Health Act, the law that authorises compulsory admissions to psychiatric hospitals and compulsory psychiatric treatments. These social workers also know about all the mental-health services o?ered by local councils and voluntary organisations, and can refer clients to them. The role of some social workers has been widened greatly in recent years by the expansion of community care. OCCUPATIONAL THERAPY ASSESSMENT Mental-health problems causing practical disabilities – for instance, inability to work, cook or look after oneself – can be assessed and helped by occupational therapists.

Treatment The aims of psychiatric treatment are to help sufferers shake o?, or at least cope with, symptoms and to gain or regain an acceptable quality of life. A range of psychological and physical treatments is available.

COUNSELLING This is a widely used ‘talking cure’, particularly in general practice. Counsellors listen to their clients, help them to explore feelings, and help them to ?nd personal and practical solutions to their problems. Counsellors do not probe into clients’ pasts or analyse them. PSYCHOTHERAPY This is the best known ‘talking cure’. The term psychotherapy is a generalisation covering many di?erent concepts. They all started, however, with Sigmund Freud (see FREUDIAN THEORY), the father of modern psychotherapy. Freud was a doctor who discovered that, as well as the conscious thoughts that guide our feelings and actions, there are powerful psychological forces of which we are not usually aware. Applying his theories to his patients’ freely expressed thoughts, Freud was able to cure many illnesses, some of which had been presumed completely physical. This was the beginning of individual analytical psychotherapy, or PSYCHOANALYSIS. Although Freud’s principles underpin all subsequent theories about the psyche, many di?erent schools of thought have emerged and in?uenced psychotherapists (see ADLER; JUNGIAN ANALYSIS; PSYCHOTHERAPY). BEHAVIOUR THERAPY This springs from theories of human behaviour, many of which are based on studies of animals. The therapists, mostly psychologists, help people to look at problematic patterns of behaviour and thought, and to change them. Cognitive therapy is very e?ective, particularly in depression and eating disorders. PHYSICAL TREATMENTS The most widely used physical treatments in psychiatry are drugs. Tranquillising and anxiety-reducing BENZODIAZEPINES like diazepam, well known by its trade name of Valium, were prescribed widely in the 1960s and 70s because they seemed an e?ective and safe substitute for barbiturates. Benzodiazepines are, however, addictive and are now recommended only for short-term relief of anxiety that is severe, disabling, or unacceptably distressing. They are also used for short-term treatment of patients drying out from alcohol.

ANTIDEPRESSANT DRUGS like amitriptyline and ?uoxetine are given to lift depressed mood and to relieve the physical symptoms that sometimes occur in depression, such as insomnia and poor appetite. The side-effects of antidepressants are mostly relatively mild, when recommended doses are not exceeded – although one group, the monoamine oxidase inhibitors, can lead to sudden and dangerous high blood pressure if taken with certain foods.

Manic depression virtually always has to be treated with mood-stabilising drugs. Lithium carbonate is used in acute mania to lower mood and stop psychotic symptoms; it can also be used in severe depression. However lithium’s main use is to prevent relapse in manic depression. Long-term unwanted effects may include kidney and thyroid problems, and short-term problems in the nervous system and kidney may occur if the blood concentration of lithium is too high – therefore it must be monitored by regular blood tests. Carbamazepine, a treatment for EPILEPSY, has also been found to stabilise mood, and also necessitates blood tests.

Antipsychotic drugs, also called neuroleptics, and major tranquillisers are the only e?ective treatments for relieving serious mental illnesses with hallucinations and delusions. They are used mainly in schizophrenia and include the short-acting drugs chlorpromazine and clozapine as well as the long-lasting injections given once every few weeks like ?uphenazine decanoate. In the long term, however, some of the older antipsychotic drugs can cause a brain problem called TARDIVE DYSKINESIA that affects control of movement and is not always reversible. And the antipsychotic drugs’ short-term side-effects such as shaking and sti?ness sometimes have to be counteracted by other drugs called anticholinergic drugs such as procyclidine and benzhexol. Newer antipsychotic drugs such as clozapine do not cause tardive dyskinesia, but clozapine cannot be given as a long-lasting injection and its concentration in the body has to be monitored by regular blood tests to avoid toxicity. OTHER PHYSICAL TREATMENTS The other two physical treatments used in psychiatry are particularly controversial: electroconvulsive therapy (ECT) and psychosurgery. In ECT, which can be life-saving for patients who have severe life-threatening depression, a small electric current is passed through the brain to induce a ?t or seizure. Before the treatment the patient is anaesthetised and given a muscle-relaxing injection that reduces the magnitude of the ?t to a slight twitching or shaking. Scientists do not really understand how ECT works, but it does, for carefully selected patients. Psychosurgery – operating on the brain to alleviate psychiatric illness or di?cult personality traits – is extremely uncommon these days. Stereo-tactic surgery, in which small cuts are made in speci?c brain ?bres under X-ray guidance, has super-seded the more generalised lobotomies of old. The Mental Health Act 1983 ensures that psychosurgery is performed only when the patient has given fully informed consent and a second medical opinion has agreed that it is necessary. For all other psychiatric treatments (except another rare treatment, hormone implantation for reducing the sex drive of sex o?enders), either consent or a second opinion is needed – not both. TREATMENT IN HOSPITAL Psychiatric wards do not look like medical or surgical wards and sta? may not wear uniforms. Patients do not need to be in their beds during the day, so the beds are in separate dormitories. The main part of most wards is a living space with a day room, an activity and television room, quiet rooms, a dining room, and a kitchen. Ward life usually has a certain routine. The day often starts with a community meeting at which patients and nurses discuss issues that affect the whole ward. Patients may go to the occupational therapy department during the day, but there may also be some therapy groups on the ward, such as relaxation training. Patients’ symptoms and problems are assessed continuously during a stay in hospital. When patients seem well enough they are allowed home for trial periods; then discharge can be arranged. Patients are usually followed up in the outpatient clinic at least once.

TREATING PATIENTS WITH ACUTE PSYCHIATRIC ILLNESS Psychiatric emergencies – patients with acute psychiatric illness – may develop from psychological, physical, or practical crises. Any of these crises may need quick professional intervention. Relatives and friends often have to get this urgent help because the sufferer is not ?t enough to do it or, if psychotic, does not recognise the need. First, they should ring the person’s general practitioner. If the general practitioner is not available and help is needed very urgently, relatives or friends should phone the local social-services department and ask for the duty social worker (on 24-hour call). In a dire emergency, the police will know what to do.

Any disturbed adult who threatens his or her own or others’ health and safety and refuses psychiatric help may be moved and detained by law. The Mental Health Act of 1983 authorises emergency assessment and treatment of any person with apparent psychiatric problems that ful?l these criteria.

Although admission to hospital may be the best solution, there are other ways that psychiatric services can respond to emergencies. In some districts there are ‘crisis intervention’ teams of psychiatrists, nurses, and social workers who can visit patients urgently at home (at a GP’s request) and, sometimes, avert unnecessary admission. And research has shown that home treatment for a range of acute psychiatric problems can be e?ective.

LONG-TERM TREATMENT AND COMMUNITY CARE Long-term treatment is often provided by GPs with support and guidance from psychiatric teams. That is ?ne for people whose problems allow them to look after themselves, and for those with plenty of support from family and friends. But some people need much more intensive long-term treatment and many need help with running their daily lives.

Since the 1950s, successive governments have closed the old psychiatric hospitals and have tried to provide as much care as possible outside hospital – in ‘the community’. Community care is e?ective as long as everyone who needs inpatient care, or residential care, can have it. But demand exceeds supply. Research has shown that some homeless people have long-term mental illnesses and have somehow lost touch with psychiatric services. Many more have developed more general long-term health problems, particularly related to alcohol, without ever getting help.

The NHS and Community Care Act 1990, in force since 1993, established a new breed of professionals called care managers to assess people whose long-term illnesses and disabilities make them unable to cope completely independently with life. Care managers are given budgets by local councils to assess people’s needs and to arrange for them tailor-made packages of care, including services like home helps and day centres. But co-ordination between health and social services has sometimes failed – and resources are limited – and the government decided in 1997 to tighten up arrangements and pool community-care budgets.

Since 1992 psychiatrists have had to ensure that people with severe mental illnesses have full programmes of care set up before discharge from hospital, to be overseen by named key workers. And since 1996 psychiatrists have used a new power called Supervised Discharge to ensure that the most vulnerable patients cannot lose touch with mental-health services. There is not, however, any law that allows compulsory treatment in the community.

There is ample evidence that community care can work and that it need not cost more than hospital care. Critics argue, however, that even one tragedy resulting from inadequate care, perhaps a suicide or even a homicide, should reverse the march to community care. And, according to the National Schizophrenia Fellowship, many of the 10–15 homicides a year carried out by people with severe mental illnesses result from inadequate community care.

Further information can be obtained from the Mental Health Act Commission, and from MIND, the National Association for Mental Health. MIND also acts as a campaigning and advice organisation on all aspects of mental health.... mental illness

Polypharmacy

A term applied to the administration of too many drugs to one person. Sometimes combinations of drugs are an e?ective means of treatment, reducing the risk of drug resistance. Polypharmacy, however, worsens the risk of drug interactions and of adverse effects, especially in the elderly.... polypharmacy

Sulphur

Chemical combinations of this substance were once applied topically because of their antimicrobial activity; they are no longer used.... sulphur

Cancer - Breast

Commonest form of cancer in women. Overall mortality remains about 50 per cent at five years. Appears to run in families. Strikes hard unmarried women. Married women who have no children. Those who do not nurse their babies, or who are infertile and have no child before thirty. Eight out of ten chest lumps are benign.

Symptoms. A small lump comes to light while washing, a discharge from the nipple, change in nipple size and colour, irregular contour of the breast surface. Though tissue change is likely to be a cyst, speedy diagnosis and treatment are necessary. Some hospital physicians and surgeons are known to view favourably supportive herbal aids, and do not always think in terms of radical mastectomy. Dr Finlay Ellingwood, Chicago physician (1916) cured a case by injection of one dram Echinacea root extract twice a week into the surrounding tissues.

The condition is believed to be due to a number of causes including suppression of ovulation and oestrogen secretion in pregnant and lactating women. A high fat diet is suspected of interference with the production of oestrogen. Some women are constitutionally disposed to the condition which may be triggered by trauma or emotional shock. Increase in incidence in older women has been linked with excessive sugar consumption. “Consumption overwhelms the pancreas which has to ‘push it out’ to all parts of the body (when broken down by the digestive process) whether they need it or not. The vital organs are rationed according to their requirements of nutrients from the diet. What is left over has to ‘go into store elsewhere’. And the breast is forced to take its share and store it. If it gets too much, for too long, it may rebel!” (Stephen Seely, Department of Bacteriology and Virology, Manchester)

“Women who nurse their babies less than one month are at an increased risk for breast cancer. The longer a woman breast-feeds – no matter what her age – the more the risk decreases. (Marion Tompson, co-founder, The La Leche League, in the American Journal of Epidemiology)

Lactation reduces the risk of pre-menopausal breast cancer. (Newcomb P.A. et al New England Journal of Medicine, 330 1994)

There is currently no treatment to cure metastatic breast cancer. In spite of chemotherapy, surgery and radiotherapy survival rate has not diminished. Herbs not only have a palliative effect but, through their action on hormone function offer a positive contribution towards overcoming the condition. Their activity has been widely recorded in medical literature. Unlike cytotoxic drugs, few have been known to cause alopecia, nausea, vomiting or inflammation of the stomach.

Treatment by a general medical practitioner or oncologist.

Special investigations. Low radiation X-ray mammography to confirm diagnosis. Test for detection of oestrogen receptor protein.

Treatment. Surgery may be necessary. Some patients may opt out from strong personal conviction, choosing a rigid self-disciplined approach – the Gentle Way. Every effort is made to build up the body’s natural defences (immune system).

An older generation of herbalists believed tissue change could follow a bruise on the breast, which should not be neglected but immediately painted with Tincture Arnica or Tincture Bellis perennis.

Vincristine, an alkaloid from Vinca rosea (Catharanthus roseus) is used by the medical profession as an anti-neoplastic and anti-mitotic agent to inhibit cell division.

Of possible therapeutic value. Blue Flag root, Burdock root, Chaparral, Clivers, Comfrey root, Echinacea, Figwort, Gotu Kola, Marshmallow root, Mistletoe, Myrrh, Prickly Ash bark, Red Clover, Thuja, Wild Violet, Yellow Dock.

Tea. Equal parts: Red Clover, Clivers, Gotu Kola, Wild Violet. 1 heaped teaspoon to each cup boiling water; infuse 5-15 minutes. 3 or more cups daily.

Decoctions. Echinacea, Blue Flag root, Queen’s Delight, Yellow Dock.

Tablets/capsules. Blue Flag root, Echinacea, Poke root, Mistletoe.

Formula. Echinacea 2; Gotu Kola 1; Poke root 1; Mistletoe 1; Vinca rosea 1. Mix. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Thrice daily and at bedtime. According to progress of the disease, increase dosage as tolerated.

Maria Treben’s tea. Parts: Marigold (3), Yarrow 1; Nettles 1. Mix. 2 teaspoons to each cup boiling water. 1 cup as many times daily as tolerated.

William Boericke, M.D. recommends Houseleek. E.H. Ruddock M.D. favours Figwort.

Topical. Treatments believed to be of therapeutic value or for use as a soothing application.

(1) Cold poultice: Comfrey root.

(2) Poultice of fresh Marshmallow root pulped in juicer.

(3) Injection of Extract Greater Celandine (Chelidonium), locally, gained a reputation in the Eclectic school.

(4) The action of Blood root (Sanguinaria) is well known as a paint or injection.

(5) Ragwort poultice: 2oz Ragwort boiled in half a pint potato water for 15 minutes. See: POULTICE.

(6) Popular Russian traditional remedy: Badiaga (Spongilla fluviatilis), fresh water sponge gathered in the autumn; dried plant rubbed to a powder. Poultice.

(7) Maria Treben’s Poultice: Carefully washed fresh Plantain leaves, pulped, and applied direct to the lesion.

(8) If lymph glands are affected, apply Plantain poultice to glands.

(9) Dr Brandini’s treatment. Dr Brandini, Florence, used 4 grains Citric Acid (prepared from lemons) in 1oz (30ml) water for ulcerated cancer of the breast considered incurable. “The woman’s torments were so distressing that neither she nor other patients could get any rest. Applying lint soaked in the solution, relief was instantaneous. Repeated, it was successful.”

(10) Circuta leaves. Simmered till soft and mixed with Slippery Elm bark powder as a poultice morning and night.

(11) Decoction. Simmer gently Yellow Dock roots, fine cut or powdered, 1oz to 1 pint, 20 minutes. Saturate lint or suitable material and apply.

(12) Yellow Dock ointment. Half ounce Lobelia seed, half ounce Yellow Dock root powder. Baste into an ointment base. See: OINTMENT BASE.

(13) Infusion, for use as a wash. Equal parts: Horsetail, Red Clover, Raspberry leaves. 1oz to 1 pint boiling water infuse 15 minutes.

(14) Dr Christopher’s Ointment. Half an ounce White Oak, half an ounce Garden Sage, half an ounce Tormentil, half an ounce Horsetail, half an ounce Lemon Balm. Method: Boil gently half an hour in quart water, strain. Reduce to half a pint by simmering. Add half a pound honey. Bring to boil. Skim off scum. Allow cool. Apply: twice daily on sores.

(15) Dr Finlay Ellingwood. Poke root juice. “Fresh juice from the stems, leaves and roots applied directly to diseased tissue. Exercises a selective action; induces liquefaction and promotes removal, sometimes healing the open wound and encouraging scar formation. Masses of such tissue have been known to be destroyed in a few weeks with only a scar, with no other application but the fresh juice. Produces pain at first, but is otherwise harmless.”

(16) Lesion painted with Mandrake resin. (American Podophyllum)

(17) Dust affected parts with Comfrey powder. Mucilage from Comfrey powder or crushed root with the aid of a little milk. See: COMFREY.

(18) Dr Samuel Thomson’s Cancer Plaster. “Take heads of Red Clover and fill a kettle. Boil in water for one hour. Remove and fill kettle with fresh flower heads. Boil as before in the same liquor. Strain and press heads to express all the liquor. Simmer over a low fire till of the consistency of tar. It must not burn. Spread over a piece of suitable material.”

(19) Wipe affected area with cut Houseleek. (Dr Wm Boericke)

(20) Chinese Herbalism. Take 1-2 Liang pulverised liao-ko-wang (Wickstroemia indica), mix with cold boiled water or rice wine for local compress. Also good for mastitis.

(21) Italian women once used an old traditional remedy – Fenugreek tea.

(22) A clinical trial of Vitamin D provided encouraging results. Patients with locally advanced breast cancer were given a highly active Vitamin D analogue cream to rub on their tumours. “It was effective in one third of the tumours,” said Professor Charles Coombes, clinical oncologist, Charing Cross Hospital, London.

Diet. “A diet rich in cereal products (high in dietary fibre) and green leafy vegetables (antioxidants) would appear to offer women some protection against breast cancer due to the relation between fibre and oestrogen metabolism. Meat-free diet. In a study of 75 adolescent girls, vegetarians were found to have higher levels of a hormone that women suffering from breast cancer often lack. (Cancer Research) Supplements. Daily. Chromium. Selenium (600mcg). Zinc chelate (100mg morning and evening). Beta carotene. “Low levels of Selenium and Vitamins A and E are shown in breast cancer cases.” (British Journal of Cancer 49: 321-324, 1984).

Vitamins A and D inhibit virus penetration in healthy cell walls. Multivitamin combinations should not include Vitamin B12, production of which in the body is much increased in cancerous conditions. Vitamins B-complex and C especially required.

Note: A link between sugar consumption and breast cancer has been reported by some authorities who suggest that countries at the top of the mortality table are the highest also in sugar consumption; the operative factor believed to be insulin.

Screening. Breast screening should be annual from the age of forty.

General. Mothers are encouraged to breast-feed children for the protection it offers against mammary malignancy. (Am.J. Obstet. Gyn. 15/9/1984. 150.)

Avoidance of stress situations by singing, playing an instrument. Adopt relaxation techniques, spiritual healing and purposeful meditation to arouse the immune system; intensive visualisation. Avoid the carcinogens: smoking, alcohol.

Information. Breast Cancer Care. Free Help Line. UK Telephone: 0500 245345. ... cancer - breast

Berberis Vulgaris

Linn.

Family: Berberidaceae.

Habitat: Distributed in Northwestern Himalayas.

English: Common Barberry, True Barberry.

Ayurvedic: Daruharidraa (var.).

Folk: Chatrod, Kashmal.

Action: Root and bark—used for ailments of gastrointestinal tract, liver, gallbladder, kidney and urinary tract, respiratory tract, also as a febrifuge and blood purifier.

Key application: Listed by German Commission E among unapproved herbs.

An extract with 80% berberine and additional alkaloids stimulated the bile secretion of rats by 72%. (PDR.) As cholagogue. (The British Herbal Pharmacopoeia.)

The main alkaloid is berberine (well tolerated up to 0.5 g). Berries are safe.

Bererine in small doses stimulates the respiratory system; poisonings have been observed from overdoses. Poisonings from the total herb have not been reported. (German Commission E.)

Berberine is bactericidal, amoebici- dal and trypanocidal. Berberine is an- tidiarrhoeal, asitentersinto the cytosol or binds to the cell membrane and inhibits the catalytic unit of andenylate cyclase. It is active in vitro and in animals against cholera.

Berberine stimulates bile secretion and shows sedative, hypotensive, anti- convulsant and uterine stimulant activity in animals. Alkaloid bermarine is also strongly antibacterial. It has been shown to increase white blood cell and platelet counts in animals with iatro- genic leukocytopaenia.

Berberine, berbamine and jatror- rhizine are hypotensive and sedative.

Many of the alkaloids are antineo- plastic.

The alkaloid berbamine (50 mg three times daily for 1-4 weeks) helped reverse leukopaenia induced by benzene, cancer chemotherapy or radiotherapy in a clinical study. (Francis Brinker.)

Berberine, when combined with pyrimethamine, was more effective than combinations with other antibiotics in treating chloroquine-resistant malaria. (Sharon M. Herr.)... berberis vulgaris

Chai Tea - A Famous Indian Blend

Discover the unique features of this Indian blend and learn more about how to get an interesting Chai tea every time and how to combine its ingredients for a special tasty experience. What is Chai tea Many people think Chai tea comes from China like most other types of tea. In fact, the word chai means tea in Hindi where it has its origin. Chai tea is actually a blend that combines black tea with milk, spices (like cinnamon, cloves, pepper and ginger) and sweeteners, creating a full tasty drink, perfect for you and your family. This Indian type of tea is also called “masala tea” and “spyce tea”. The smell of it draws plenty of attention and many people say that it helps them to relax. Drink Chai tea The way you make Chai tea is very important to get the right taste. Being a mixture of spices in different combinations, the brewing methods vary widely. There are traditional methods together with customized ones, depending on the spices contained in the blend. The milk should be added to the black tea while it is still boiling. This will make the tea turn darker and it will get a stronger flavor than many other type of teas. Chai Tea Benefits Learn how the amazing benefits of black tea combine successfully with those of other herbs and spices that form this unique mixture and how can they help you lead a healthier life. Chai tea prevents cardiovascular diseases. Catechins and polyphenols from the black tea lowers blood pressure and reduces bad cholesterol, thus preventing the formation of blood clots. Spices contained are perfect to fight viruses and bacteria. If you suffer from digestion problems, be sure that drinking this tea will help you in this regard. Chai tea is good if you want to treat colds, flu or even fever. It is a very good coffee substitute and the addition of milk and honey provide you even more health benefits within each cup. Chai Tea Side Effects Because it contains many ingredients in one mixture, Chai tea may have some precautions. For example, if you suffer from ulcers and heartburns you shouldn’t drink it as it may worsen your condition. If you have intolerance to lactose, you can abandon the idea of adding milk into it. If you have problems with caffeine, try to chose another blend, based or green tea or anything but black tea. Chai tea is an interesting tea with lots of health benefits. Its numerous ways of mixing its ingredients and the different flavor according to it will certainly not bore you, because you can create a new one every time you drink it.... chai tea - a famous indian blend

Ebers Papyrus

The first medical records of Ancient Egypt containing 876 substances, most of them herbal including Castor oil, Valerian, Dill, Senna leaves; and goat fat as a base for ointments. The papyrus, written about 1500 BC contains prescriptions and formulae covering wide range. Medicines still in use today: Myrrh, Wormwood, Peppermint, Anise, Fennel, Lotus flowers, Linseed, Juniper berries, Gentian, etc. ... ebers papyrus

Gerard House

Founded by Thomas Bartram, 1958, with formulae used with success in his busy practice as Consulting Medical Herbalist, Bournemouth, England. Objects: to spread knowledge of herbal medicine and to provide a reliable service of safe alternatives to drugs. Foundation named after John Gerard in the belief that the science of the herbalist makes an important contribution towards national health. ... gerard house

Fingerprint

An impression left on a surface by the pattern of fine curved ridges on the skin of the fingertips. The ridges occur in 4 patterns: loops, arches, whorls, and compounds (combinations of the other 3). No 2 people, not even identical twins, have the same fingerprints. (See also genetic fingerprinting.)... fingerprint

Carcinoma

n. *cancer that arises in epithelium, the tissue that lines the skin and internal organs of the body. It may occur in any tissue containing epithelial cells. In many cases the site of origin of the tumour may be identified by the nature of the cells it contains. Organs may exhibit more than one type of carcinoma; for example, an adenocarcinoma and a squamous carcinoma may be found in the cervix (but not usually concurrently). Treatment depends on the nature of the primary tumour, different types responding to different drug combinations. —carcinomatous adj.... carcinoma

Brain, Diseases Of

These consist either of expanding masses (lumps or tumours), or of areas of shrinkage (atrophy) due to degeneration, or to loss of blood supply, usually from blockage of an artery.

Tumours All masses cause varying combinations of headache and vomiting – symptoms of raised pressure within the inexpansible bony box formed by the skull; general or localised epileptic ?ts; weakness of limbs or disordered speech; and varied mental changes. Tumours may be primary, arising in the brain, or secondary deposits from tumours arising in the lung, breast or other organs. Some brain tumours are benign and curable by surgery: examples include meningiomas and pituitary tumours. The symptoms depend on the size and situation of the mass. Abscesses or blood clots (see HAEMATOMA) on the surface or within the brain may resemble tumours; some are removable. Gliomas ( see GLIOMA) are primary malignant tumours arising in the glial tissue (see GLIA) which despite surgery, chemotherapy and radiotherapy usually have a bad prognosis, though some astrocytomas and oligodendronogliomas are of low-grade malignancy. A promising line of research in the US (in the animal-testing stage in 2000) suggests that the ability of stem cells from normal brain tissue to ‘home in’ on gliomal cells can be turned to advantage. The stem cells were chemically manipulated to carry a poisonous compound (5-?uorouracil) to the gliomal cells and kill them, without damaging normal cells. Around 80 per cent of the cancerous cells in the experiments were destroyed in this way.

Clinical examination and brain scanning (CT, or COMPUTED TOMOGRAPHY; magnetic resonance imaging (MRI) and functional MRI) are safe, accurate methods of demonstrating the tumour, its size, position and treatability.

Strokes When a blood vessel, usually an artery, is blocked by a clot, thrombus or embolism, the local area of the brain fed by that artery is damaged (see STROKE). The resulting infarct (softening) causes a stroke. The cells die and a patch of brain tissue shrinks. The obstruction in the blood vessel may be in a small artery in the brain, or in a larger artery in the neck. Aspirin and other anti-clotting drugs reduce recurrent attacks, and a small number of people bene?t if a narrowed neck artery is cleaned out by an operation – endarterectomy. Similar symptoms develop abruptly if a blood vessel bursts, causing a cerebral haemorrhage. The symptoms of a stroke are sudden weakness or paralysis of the arm and leg of the opposite side to the damaged area of brain (HEMIPARESIS), and sometimes loss of half of the ?eld of vision to one side (HEMIANOPIA). The speech area is in the left side of the brain controlling language in right-handed people. In 60 per cent of lefthanders the speech area is on the left side, and in 40 per cent on the right side. If the speech area is damaged, diffculties both in understanding words, and in saying them, develops (see DYSPHASIA).

Degenerations (atrophy) For reasons often unknown, various groups of nerve cells degenerate prematurely. The illness resulting is determined by which groups of nerve cells are affected. If those in the deep basal ganglia are affected, a movement disorder occurs, such as Parkinson’s disease, hereditary Huntington’s chorea, or, in children with birth defects of the brain, athetosis and dystonias. Modern drugs, such as DOPAMINE drugs in PARKINSONISM, and other treatments can improve the symptoms and reduce the disabilities of some of these diseases.

Drugs and injury Alcohol in excess, the abuse of many sedative drugs and arti?cial brain stimulants – such as cocaine, LSD and heroin (see DEPENDENCE) – can damage the brain; the effects can be reversible in early cases. Severe head injury can cause localised or di?use brain damage (see HEAD INJURY).

Cerebral palsy Damage to the brain in children can occur in the uterus during pregnancy, or can result from rare hereditary and genetic diseases, or can occur during labour and delivery. Severe neurological illness in the early months of life can also cause this condition in which sti? spastic limbs, movement disorders and speech defects are common. Some of these children are learning-disabled.

Dementias In older people a di?use loss of cells, mainly at the front of the brain, causes ALZHEIMER’S DISEASE – the main feature being loss of memory, attention and reasoned judgement (dementia). This affects about 5 per cent of the over-80s, but is not simply due to ageing processes. Most patients require routine tests and brain scanning to indicate other, treatable causes of dementia.

Response to current treatments is poor, but promising lines of treatment are under development. Like Parkinsonism, Alzheimer’s disease progresses slowly over many years. It is uncommon for these diseases to run in families. Multiple strokes can cause dementia, as can some organic disorders such as cirrhosis of the liver.

Infections in the brain are uncommon. Viruses such as measles, mumps, herpes, human immunode?ciency virus and enteroviruses may cause ENCEPHALITIS – a di?use in?ammation (see also AIDS/HIV).

Bacteria or viruses may infect the membrane covering the brain, causing MENINGITIS. Viral meningitis is normally a mild, self-limiting infection lasting only a few days; however, bacterial meningitis – caused by meningococcal groups B and C, pneumococcus, and (now rarely) haemophilus – is a life-threatening condition. Antibiotics have allowed a cure or good control of symptoms in most cases of meningitis, but early diagnosis is essential. Severe headaches, fever, vomiting and increasing sleepiness are the principal symptoms which demand urgent advice from the doctor, and usually admission to hospital. Group B meningococcus is the commonest of the bacterial infections, but Group C causes more deaths. A vaccine against the latter has been developed and has reduced the incidence of cases by 75 per cent.

If infection spreads from an unusually serious sinusitis or from a chronically infected middle ear, or from a penetrating injury of the skull, an abscess may slowly develop. Brain abscesses cause insidious drowsiness, headaches, and at a late stage, weakness of the limbs or loss of speech; a high temperature is seldom present. Early diagnosis, con?rmed by brain scanning, is followed by antibiotics and surgery in hospital, but the outcome is good in only half of affected patients.

Cerebral oedema Swelling of the brain can occur after injury, due to engorgement of blood vessels or an increase in the volume of the extravascular brain tissue due to abnormal uptake of water by the damaged grey (neurons) matter and white (nerve ?bres) matter. This latter phenomenon is called cerebral oedema and can seriously affect the functioning of the brain. It is a particularly dangerous complication following injury because sometimes an unconscious person whose brain is damaged may seem to be recovering after a few hours, only to have a major relapse. This may be the result of a slow haemorrhage from damaged blood vessels raising intracranial pressure, or because of oedema of the brain tissue in the area surrounding the injury. Such a development is potentially lethal and requires urgent specialist treatment to alleviate the rising intracranial pressure: osmotic agents (see OSMOSIS) such as mannitol or frusemide are given intravenously to remove the excess water from the brain and to lower intracranial pressure, buying time for de?nitive investigation of the cranial damage.... brain, diseases of

Cranberry Tea

High in antioxidants and vitamins, cranberries are one of nature’s super foods, helping to fight free radicals and lead a healthier life. Discover how a cup of Cranberry tea can make your life better. About Cranberry Tea The cranberry plant is a small evergreen shrub and trailing vine, which grows in many regions from around the world, mostly in mountain forests. It has slender, wiry stems and evergreen leaves. The cranberry bush produces pink or purple flowers in the spring and bright red berries in the fall. It is edible, with an acidic taste that can overwhelm its sweetness. Cranberries are normally considered too sharp to be eaten plain and raw, as they are not only sour but bitter as well. Cranberries are commonly found in juice drinks, compote or jelly, in baking or even cranberry wine. Raw cranberries have moderate levels of vitamin C, E, K, dietary fiber and the essential dietary mineral, manganese, as well as a balanced profile of other essential micronutrients. Cranberry tea has a tasty flavor and can be drunk in many forms and combinations. Brew Cranberry Tea Only the fruits are suitable for Cranberry tea. There are many ways to prepare a tasty tea. For example, you can combine the powdered cranberry fruit with sugar-free teas like green tea and rooibos tea, or with herbal infusions like cinnamon tea. Cranberry tea bags are also widely available for ready infusion in hot or near-boiling water. There are also a lot of ways and mixtures to prepare tasty ice cranberry tea. Cranberry Tea  Benefits Cranberry tea has amazing benefits for your health. Cranberry tea is an immunity booster and an overall tonic due to the antioxidants contained. Cranberry tea is used to prevent and slow the progression of the gum disease or gingivitis. Regular intake of the tea in combination of a healthy diet can result in weight loss and a healthier overall body. Cranberry tea helps detoxify and protect the kidneys. It can be used to treat and prevent urinary tract infection. Cranberry tea may have beneficial effects in fighting eye problems. Cranberry Tea Side Effects The good news is that there are no side effects associated to cranberry tea. You can include cranberry tea in your daily routine with no fear what so ever and you can enjoy its many benefits.... cranberry tea

Cone

n. one of the two types of light-sensitive cells in the *retina of the eye (compare rod). The human retina contains 6–7 million cones; they function best in bright light and are essential for acute vision (receiving a sharp accurate image). The area of the retina called the *fovea contains the greatest concentration of cones. Cones can also distinguish colours. It is thought that there are three types of cone, each sensitive to the wavelength of a different primary colour – red, green, or blue. Other colours are seen as combinations of these three primary colours.... cone

Keloid

n. an overgrowth of fibrous scar tissue following trauma to the skin. It does not resolve spontaneously but may be flattened by silicone gels, applied pressure, injections of potent corticosteroids, or intralesional excision (or combinations of these). Keloid formation is particularly common at certain sites, such as the breastbone or ear lobe; surgical excision of benign (nonmalignant) lesions from such sites is therefore best avoided. See also scar.... keloid

Mens

multiple endocrine neoplasia syndromes, designated as type 1 (Wermer’s syndrome), type 2A (Sipple’s syndrome), and type 2B. These involve tumour formation or hyperplasia in various combinations of endocrine glands. Type 1 involves the parathyroid, pituitary, and pancreas, whereas type 2A involves the thyroid medullary cells, the adrenal medulla (*phaeochromocytoma), and the parathyroids. Type 2B is similar to 2A, but patients tend to resemble people with *Marfan’s syndrome and have multiple *neuromas on their mucous membranes. These conditions are inherited as autosomal *dominant characteristics.... mens

Cymbopogon Nardus

(Linn.) Rendle.

Synonym: Andropogon nardus Linn.

Family: Poaceae.

Habitat: Mainly in South India; cultivated to a small extent in warmer parts of India.

English: Ceylon Citronella Grass.

Ayurvedic: Jambir-trn (var.).

Siddha/Tamil: Kamachipillu.

Action: Leaf—stomachic, carminative, spasmolytic, mild astringent. Essential oil—stimulant, carminative, diaphoretic, rubefacient, antiseptic, antibacterial, antifungal, larvicidal.

Lemongrass and lemongrass oil preparations are used almost exclusively in combinations for disorders and discomforts of gastrointestinal tract, muscle pain and neuralgia, colds, various nervous disturbances and for conditions of exhaustion.

Major constituents of the essential oil are: citronellal 31.6, neral 28.6, cit- ronellol 10.6, elemicine 7.3, geranyl acetate 4.6, elemol 3.7, limonene 3.2 and isopulegol 2.7%.

Citronella oil is also used as an insect repellent.... cymbopogon nardus

Devil's Bit

Scabiosa succisa. N.O. Compositae.

Synonym: Ofbit.

Habitat: Heaths and pastures.

Features ? Stem up to eighteen inches, slender, hairy, well-branched. Leaves opposite, oval-lanceolate, slightly serrate, nearly sessile ; root leaves stalked, ovoid, smooth at margins. Flowers dark purple, on long stalk, florets bunched together.

The common name is derived from the root. which appears to have been bitten off at the end, with which vandalism "the devil" is credited.

Part used ? Herb.

Action: Demulcent, diaphoretic.

Included in formulae for coughs and feverish conditions generally. A 1 ounce to 1 pint infusion may be taken warm in wineglassful doses frequently.... devil's bit

Gravel Root

Eupatorium purpureum. N.O. Compositae.

Synonym: Eupatorium purpureum is also called Gravel Weed and Queen of the

Meadow, from which the medicinal "Gravel Root" is obtained.

Habitat: Gravel Root is a native of the United States, and must not be confused with the English Queen of the Meadow or Meadowsweet (Spiraea ulmaria).

Features ? Our present subject is a member of the Boneset (Eupatorium perfoliatum) family, and sometimes reaches six feet in height at full growth. It is peculiar for a purple band about an inch broad round the leaf joint. Pale purple to white flowers bloom in August and September. The rhizome, as the medicinal "root" should more properly be termed, is hard and tough, up to an inch thick, with a nearly white wood and thin grey-brown bark. Short, lateral branches give off thin, tough root several inches long.

Part used ? Root.

Action: Diuretic and stimulant.

Gravel root is much prescribed for cases of stone in the bladder and certain other troubles of the kidneys and urinary apparatus. A decoction of 1 ounce of the root to 1 pint (reduced from 1 1/2 pints) of water is made, and taken in wineglass doses. Gravel root is also met with in nervine formulae, in which its tonic properties are recognised.

The American physio-medical or "Thomsonite" M.D., F. H. England, has said that Gravel Root "induces very little stimulation. It expends nearly all its influence on the kidneys, bladder and uterus. It probably influences the whole sympathetic nervous system. Its use promotes the flow of urine as scarcely anything else will."... gravel root

Hard Water

The term applied to water that contains a large amount of calcium and magnesium salts (lime salts). These form an insoluble curd with soap and thus interfere with the use of the water for washing. Hard water is especially found in districts where the soil is chalky. Temporary hardness, which is due mainly to the presence of bicarbonates of lime, can be remedied by boiling, when the lime is precipitated as carbonate of lime. Permanent hardness is not remedied by boiling, and is due to the presence of a large amount of sulphate of lime. It may be removed by the addition of sodium carbonate (washing soda) or by the Permutit process which involves the use of various combinations of silicate of alumina and soda. In the past, hard water was often blamed for many ills – without any convincing evidence. Epidemiologists suggest that drinking soft water may lead to a greater risk of heart disease.... hard water

Microscope

n. an instrument for producing a greatly magnified image of an object, which may be so small as to be invisible to the naked eye. Light or optical microscopes use light as a radiation source for viewing the specimen and combinations of lenses to magnify the image; these are usually an *objective and an *eyepiece. See also electron microscope; operating microscope; ultramicroscope. —microscopical adj. —microscopy n.... microscope

Pharmacopoeia

n. a book containing a list of the drugs used in medicine, with details of their formulae, methods of preparation, dosages, standards of purity, etc.... pharmacopoeia

Hla System

The major histocompatibility complex, or human leucocyte antigen (HLA) region, consists of genetically determined antigens, situated on chromosome 6. Found in most tissues, though to a di?ering extent, the four gene loci are known as A, B, C, D, while the individual alleles at each locus are numbered 1, 2, 3, etc. The number of possible combinations is thus enormous, and the chance of two unrelated people being identical for HLA is very low.

HLA incompatibility causes the immune response, or rejection reaction, that occurs with unmatched tissue grafts. Strong associations between HLA and susceptibility to certain diseases – notably the AUTOIMMUNE DISORDERS such as rheumatoid arthritis, insulin-dependent diabetes, and thyrotoxicosis – have been described. Certain HLA antigens occur together more frequently than would be expected by chance (linkage disequilibrium), and may have a protective e?ect, conferring resistance to a disease. (See IMMUNITY.)... hla system

Meiosis

Meiosis, or reduction division, is the form of cell division that only occurs in the gonads (see GONAD) – that is, the testis (see TESTICLE) and the ovary (see OVARIES) – giving rise to the germ cells (gametes) of the sperms (see SPERMATOZOON) and the ova (see OVUM).

Two types of sperm cells are produced: one contains 22 autosomes and a Y sex chromosome (see SEX CHROMOSOMES); the other, 22 autosomes and an X sex chromosome. All the ova, however, produced by normal meiosis have 22 autosomes and an X sex chromosome.

Two divisions of the NUCLEUS occur (see also CELLS) and only one division of the chromosomes, so that the number of chromosomes in the ova and sperms is half that of the somatic cells. Each chromosome pair divides so that the gametes receive only one member of each pair. The number of chromosomes is restored to full complement at fertilisation so that the zygote has a complete set, each chromosome from the nucleus of the sperm pairing up with its corresponding partner from the ovum.

The ?rst stage of meiosis involves the pairing of homologous chromosomes which join together and synapse lengthwise. The chromosomes then become doubled by splitting along their length and the chromatids so formed are held together by centromeres. As the homologous chromosomes – one of which has come from the mother, and the other from the father – are lying together, genetic interchange can take place between the chromatids and in this way new combinations of GENES arise. All four chromatids are closely interwoven and recombination may take place between any maternal or any paternal chromatids. This process is known as crossing over or recombination. After this period of interchange, homologous chromosomes move apart, one to each pole of the nucleus. The cell then divides and the nucleus of each new cell now contains 23 and not 46 chromosomes. The second meiotic division then occurs, the centromeres divide and the chromatids move apart to opposite poles of the nucleus so there are still 23 chromosomes in each of the daughter nuclei so formed. The cell divides again so that there are four gametes, each containing a half number (haploid) set of chromosomes. However, owing to the recombination or crossing over, the genetic material is not identical with either parent or with other spermatozoa.... meiosis

Myalgic Encephalomyelitis (me)

A syndrome in which various combinations of extreme fatiguability, muscle pain, lack of concentration, panic attacks, memory loss and depression occur. Its existence and causes have been the subject of controversy re?ected in the variety of names given to the syndrome: CHRONIC FATIGUE SYNDROME (CFS), post-viral fatigue syndrome, Royal Free disease, epidemic neuromyasthenia and Icelandic disease. ME often follows virus infections of the upper respiratory tract or gut, but it is not clear whether this is an association or cause-ande?ect. It may occur in epidemics or as individual cases. Physical examination shows no evidence of diagnosable disease and there is no diagnostic test – diagnosis usually being made by excluding other possible disorders. The sufferer usually recovers in time, although sometimes recovery may take many months or even years. The most severely affected may be bedridden and may need tube-feeding. There is no speci?c curative treatment, but symptomatic treatment such as resting in the early stages may help. Some experts believe that the illness has a psychological element, and sufferers have been treated with COGNITIVE BEHAVIOUR THERAPY. In 1998 the Chief Medical O?cer set up a multidisciplinary working group, including patients, to consider possible cures and treatments for ME/CFS. The report (2002) concluded that the disorder should be recognised as chronic and treatable, but there was no clear agreement on cause(s) and treatment(s). Meanwhile research continues, including a programme by the Centre of Disease Control in Atlanta, USA. Su?erers may ?nd it helpful to consult the ME Association.... myalgic encephalomyelitis (me)

Neuron(e)

Also known as a nerve cell, this is the basic cellular building-block of the NERVOUS SYSTEM, which contains billions of neurones linked in a complex network and acting in di?erent combinations to keep the body informed about the outside world, and then to organise and activate appropriate responses. There are three main types of neurone:

Sensory These carry signals to the central nervous system (CNS) – the BRAIN and SPINAL CORD – from sensory receptors. These receptors respond to di?erent stimuli such as touch, pain, temperature, smells, sounds and light.

Motor These carry signals from the CNS to activate muscles or glands.

Interneurons These provide the interconnecting ‘electrical network’ within the CNS.

Structure Each neurone comprises a cell body, several branches called dendrites, and a single ?lamentous ?bre called an AXON. Axons may be anything from a few millimetres to a metre long; at their end are several branches acting as terminals through which electrochemical signals are sent to target cells, such as those of muscles, glands or the dendrites of another axon.

Axons of several neurones are grouped

together to form nerve tracts within the brain or spinal cord or nerve-?bres outside the CNS. Each nerve is surrounded by a sheath and contains bundles of ?bres. Some ?bres are medullated, having a sheath of MYELIN which acts as insulation, preventing nerve impulses from spreading beyond the ?bre conveying them.

The cellular part of the neurones makes up the grey matter of the brain and spinal cord – the former containing 600 million neurones. The dendrites meet with similar outgrowths from other neurones to form synapses. White matter is the term used for that part of the system composed of nerve ?bres.

Functions of nerves The greater part of the bodily activity originates in the nerve cells (see NERVE). Impulses are sent down the nerves which act simply as transmitters. The impulse causes sudden chemical changes in the muscles as the latter contract (see MUSCLE). The impulses from a sensory ending in the skin pass along a nerve-?bre to affect nerve cells in the spinal cord and brain, where they are perceived as a sensation. An impulse travels at a rate of about 30 metres (100 feet) per second. (See NERVOUS IMPULSE.)

The anterior roots of spinal nerves consist of motor ?bres leading to muscles, the posterior roots of sensory ?bres coming from the skin. The terms, EFFERENT and AFFERENT, are applied to these roots, because, in addition to motor ?bres, ?bres controlling blood vessels and secretory glands leave the cord in the anterior roots. The posterior roots contain, in addition to sensory ?bres, the nerve-?bres that transmit impulses from muscles, joints and other organs, which among other neurological functions provide the individual with his or her

proprioceptive faculties – the ability to know how various parts of the body are positioned.

The connection between the sensory and motor systems of nerves is important. The simplest form of nerve action is that known as automatic action. In this, a part of the nervous system, controlling, for example, the lungs, makes rhythmic discharges to maintain the regular action of the respiratory muscles. This controlling mechanism may be modi?ed by occasional sensory impressions and chemical changes from various sources.

Re?ex action This is an automatic or involuntary activity, prompted by fairly simple neurological circuits, without the subject’s consciousness necessarily being involved. Thus a painful pinprick will result in a re?ex withdrawal of the affected ?nger before the brain has time to send a ‘voluntary’ instruction to the muscles involved.

Voluntary Actions are more complicated than re?ex ones. The same mechanism is involved, but the brain initially exerts an inhibitory or blocking e?ect which prevents immediate re?ex action. Then the impulse, passing up to the cerebral hemispheres, stimulates cellular activity, the complexity of these processes depending upon the intellectual processes involved. Finally, the inhibition is removed and an impulse passes down to motor cells in the spinal cord, and a muscle or set of muscles is activated by the motor nerves. (Recent advances in magnetic resonance imaging (MRI) techniques have provided very clear images of nerve tracts in the brain which should lead to greater understanding of how the brain functions.) (See BRAIN; NERVOUS SYSTEM; SPINAL CORD.)... neuron(e)

Protein

The term applies to members of a group of non-crystallisable nitrogenous substances widely distributed in the animal and vegetable kingdoms, and forming the characteristic materials of their tissues and ?uids. They are essentially combinations of AMINO ACIDS. They mostly dissolve in water and are coagulated by heat and various chemical substances. Typical examples of protein substances are white of egg and gelatin.

Proteins constitute an essential part of the diet as a source of energy, and for the replacement of protein lost in the wear and tear of daily life. Their essential constituent from this point of view is the nitrogen which they contain. To be absorbed, or digested, proteins have to be broken down into their constituent amino acids. The adult human body can maintain nitrogenous equilibrium on a mixture of eight amino acids, which are therefore known as the essential (or indispensable) amino acids. They are isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine. In addition, infants require histidine.... protein

Oncology

The management of MALIGNANT disease – a major health problem since successful management requires close liaison between the patient, surgeons, physicians, oncologists, haematologists, paediatricians and other specialists. Diagnosis may involve various investigations and often requires a BIOPSY. Once a diagnosis has been established, treatment may involve surgery, radiotherapy or chemotherapy (or various combinations as required) – see below, and main dictionary entries.

Surgery may be most common, and is often the only treatment, for some gastrointestinal tumours, soft-tissue tumours, gynaecological tumours and advanced cancers of the head and neck.

Radiotherapy uses ionising radiation to kill tumour cells. Radiation is by naturally occurring isotopes (see ISOTOPE) or arti?cially produced X-RAYS. Germ-cell tumours (see SEMINOMA; TERATOMA) and malignant lymphomas (see LYMPHOMA) appear to be particularly sensitive to irradiation, and many head and neck tumours, gynaecological cancers, and localised cancers of the PROSTATE GLAND and URINARY BLADDER are curable with radiotherapy. It is also a valuable means of reducing pain from bone metastases (see METASTASIS). Unpleasant side-effects are common: chie?y lethargy, loss of appetite and dry, itchy skin symptoms.

Chemotherapy is also an important treatment in germ-cell tumours (see above); in some forms of LEUKAEMIA and lymphoma; in ovarian cancer (following surgery – see OVARIES, DISEASES OF); and in small-cell lung cancer (although most patients die within 18 months – see LUNGS, DISEASES OF). It is also used in some breast cancers (see BREASTS, DISEASES OF); advanced myeloma (see MYELOMATOSIS); sarcomas (see under CANCER); and some childhood cancers (such as WILMS’ TUMOUR).

More than 20 substances are in common use, the major classes being ALKYLATING AGENTS (e.g. cyclophosphamide, chlorambucil, busul fan); ANTIMETABOLITES (e.g. methotrexate); VINCA ALKALOIDS (e.g. vincristine, vinblastine); and antitumour ANTIBIOTICS (e.g. actinomycin D). Choice of agent and the appropriate regimen requires expert guidance. Common side-effects include nausea and vomiting, bone-marrow suppression and ALOPECIA, with each substance having its own spectrum of unwanted effects.

Good doctor-patient communication, with the sharing of information and bringing the patient into the decision-making process, is vital even if time-consuming and exhausting.

Equally imortant treatment is PALLIATIVE, for example to ensure e?ective pain or nausea control. Common sources of pain in cancer may involve bone, nerve compression, soft tissue, visceral, myofascial, constipation, muscle spasm, low-back pain, joint pain (e.g. capsulitis) and chronic post-operative pain. Patients may be suffering from more than one pain, all of which should be identi?ed. The aim should be to eliminate pain.

There are three rungs of the analgesic ladder; if one rung fails, the next one should be tried:

(1) non-opioid drugs – for example, aspirin, PARACETAMOL, NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS); (2) weak opioids – for example, CODEINE, DIHYDROCODEINE, dextropropoxyphene; (3) strong opioids

– for example, MORPHINE, DIAMORPHINE, buprenorphine. Oral treatment is always preferable, unless prevented by severe vomiting. (See also CANCER; ONCOLOGIST; PAIN; PALLIATIVE CARE.)... oncology

Scullcap

Scutellaria lateriflora. N.O. Labiateae.

Synonym: Sometimes named Skullcap, and locally known as Madweed.

Habitat: Indigenous to the United States, the plant is also found in England on the banks of streams and in wet ditches.

First introduced by the Spaniards in 1563 as a specific for syphilis, this claim has long been disproved, although the root undoubtedly possesses active alterative principles. It is consequently now held in high regard as a blood purifier, and is usually administered with other alteratives, notably Burdock.

Compound decoctions of Sarsaparilla are very popular as a springtime medicine, and Coffin's prescription will be found in the Herbal Formulae section of this volume.... scullcap

Vinca Rosea

Linn.

Synonym: Catharanthus roseus (Linn.) G.Don.

Family: Apocynaceae.

Habitat: Native of West Indies; commonly grown in Indian gardens.

English: Madagascar Periwinkle.

Ayurvedic: Sadaapushpaa, Sadam- pushpa, Nityakalyaani, Sadaaba- haar.

Siddha: Nithiya kalyani, Sudukadu mallikai.

Action: Cytotoxic.

Over one hundred monomeric and bisindole alkaloids have been isolated.

The indole alkaloid, vincamine, is a vasodilator; the bisindole alkaloids vinblastine and vincristine proved to be highly effective as cancer chemothera- peutic agents.

Vinblastine and vincristine are clinically used in a number of thrombo- cytopenic disorders, such as refractory idiopathic thrombocytopenic purpurea and haemolytic anaemia.

Vinblastine in combination with other chemotherapeutic agents (cis- platin and bleomycin) is used for the treatment of metastatic testicular cancer; also against bladder cancer, breast cancer, non-small cell lung cancer and Hodgkin's lymphoma in combination with other drugs.

Vincristine, in various combinations, is highly effective in acute leukemia in children and lymphocytic leukemia; and pediatric tumours. (The Treatise on Indian Medicinal Plants.)... vinca rosea

Rheumatoid Arthritis

A chronic in?ammation of the synovial lining (see SYNOVIAL MEMBRANE) of several joints, tendon sheaths or bursae which is not due to SEPSIS or a reaction to URIC ACID crystals. It is distinguished from other patterns of in?ammatory arthritis by the symmetrical involvement of a large number of peripheral joints; by the common blood-?nding of rheumatoid factor antibody; by the presence of bony erosions around joints; and, in a few, by the presence of subcutaneous nodules with necrobiotic (decaying) centres.

Causes There is a major immunogenetic predisposition to rheumatoid arthritis in people carrying the HLA-DR4 antigen (see HLA SYSTEM). Other minor immunogenetic factors have also been implicated. In addition, there is a degree of familial clustering which suggests other unidenti?ed genetic factors. Genetic factors cannot alone explain aetiology, and environmental and chance factors must be important, but these have yet to be identi?ed.

Epidemiology Rheumatoid arthritis more commonly occurs in women from the age of 30 onwards, the sex ratio being approximately 4:1. Typical rheumatoid arthritis may occur in adolescence, but in childhood chronic SYNOVITIS usually takes one of a number of di?erent patterns, classi?ed under juvenile chronic arthritis.

Pathology The primary lesion is an in?ammation of the synovial membrane of joints. The synovial ?uid becomes diluted with in?ammatory exudate: if this persists for months it leads to progressive destruction of articular CARTILAGE and BONE. Cartilage is replaced by in?ammatory tissue known as pannus; a similar tissue invades bone to form erosions. Synovitis also affects tendon sheaths, and may lead to adhesion ?brosis or attrition and rupture of tendons. Subcutaneous and other bursae may be involved. Necrobiotic nodules also occur at sites outside synovium, including the subcutaneous tissues, the lungs, the pericardium and the pleura.

Clinical features Rheumatoid arthritis varies from the very mild to the severely disabling. Many mild cases probably go undiagnosed. At least 50 per cent of patients continue to lead a reasonably normal life; around 25 per cent are signi?cantly disabled in terms of work and leisure activities; and a minority become markedly disabled and are limited in their independence. There is often an early acute phase, followed by substantial remission, but in other patients gradual step-wise deterioration may occur, with progressive involvement of an increasing number of joints.

The diagnosis of rheumatoid arthritis is largely based on clinical symptoms and signs. Approximately 70 per cent of patients have rheumatoid factor ANTIBODIES in the SERUM but, because of the large number of false positives and false negatives, this test has very little value in clinical practice. It may be a useful pointer to a worse prognosis in early cases if the level is high. X-RAYS may help in diagnosing early cases and are particularly helpful when considering surgery or possible complications such as pathological fracture. Patients commonly develop ANAEMIA, which may be partly due to gastrointestinal blood loss from antiin?ammatory drug treatment (see below).

Treatment involves physical, pharmacological, and surgical measures, together with psychological and social support tailored to the individual patient’s needs. Regular activity should be maintained. Resting of certain joints such as the wrist with splints may be helpful at night or to assist prolonged manual activities. Sound footwear is important. Early use of antirheumatic drugs reduces long-term disability. Drug treatment includes simple ANALGESICS, NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS), and slow-acting drugs including GOLD SALTS (in the form of SODIUM AUROTHIOMALATE), PENICILLAMINE, SULFASALAZINE, METHOTREXATE and AZATHIOPRINE.

The non-steroidal agents are largely e?ective in reducing pain and early-morning sti?ness, and have no e?ect on the chronic in?ammatory process. It is important, especially in the elderly, to explain to patients the adverse effects of NSAIDs, the dosage of which can be cut by prescribing paracetamol at the same time. Combinations of anti-rheumatic drugs seem better than single agents. The slow-acting drugs take approximately three months to act but have a more global e?ect on chronic in?ammation, with a greater reduction in swelling and an associated fall in erythrocyte sedimentation rate (ESR) and rise in the level of HAEMOGLOBIN. Local CORTICOSTEROIDS are useful, given into individual joints. Systemic corticosteroids carry serious problems if continued long term, but may be useful under special circumstances. Much research is currently going on into the use of tumour necrosis factor antagonists such as INFLIXIMAB and etanercept, but their precise role remains uncertain.... rheumatoid arthritis

Tea For Water Retention

Water retention or Edema is an affection which is more commonly found in the legs and hands due to gravity. Generally, water retention makes your organs grow bigger and decrease their action. The swelling may affect the entire body or just a part of it (lungs, kidney, hands and feet) within days or month- a relatively short amount of time. This affection is caused by flu, cold or by overexposing your body to very low temperatures. How a Tea for Water Retention Works A Tea for Water Retention’s main purpose is to eliminate the surplus of water and heal the affected areas. Traditional medicine has developed some very effective drug combinations during the past years, but alternative medicine fans think that herbal treatments remain the real deal and that there’s no reason to stress out your liver. Efficient Tea for Water Retention When choosing a Tea for Water Retention, you must keep in mind the fact that this must be both very effective (contains a large amount of active constituents) and safe (water retention is an affection which takes time to heal so you don’t want anything to interfere with your treatment). If you don’t know which teas to choose from, here’s a list to give you a hand: - Green Tea – contains the right amount of active ingredients capable to flush all water out of your system and calm the affected areas. Don’t take more than 2 cups per day and don’t take it at all if you are experiencing menstrual or menopausal symptoms in order to avoid stomach ulcerations. - Stinging Nettle Tea – this Tea for Water Retention is a natural purgative and diuretic which is generally used to treat prostate problems. However, this is not one of the safest teas, so may want to check with your doctor before starting an herbal treatment based on it. - Dandelion Tea – the decoction is made from this plant’s roots and it’s well known for its curative properties, which include constipation and urinary tract infections. The Dandelion Tea will help your body get rid of the unnecessary water and improve your general health. - Peppermint Tea – this is one Tea for Water Retention one hundred percent safe! You can also take it to treat ailments of the respiratory and digestive systems, such as cough, flu, colds, pleurisy, pulmonary edema, upset stomach and gastritis. If you’ve decided to give up coffee, peppermint tea is a great alternative! Tea for Water Retention Side Effects When taken properly, these teas are generally safe. However, don’t exceed the number of cups in order to avoid digestive tract problems, such as diarrhea (some of these teas have a powerful diuretic effect), ulcers, uterine contractions or vomiting. If you’ve been taking one of these teas for a while and you’ve noticed some unusual reactions, ask for medical help as soon as possible! Don’t take a Tea for Water Retention if you’re pregnant, breastfeeding, on blood thinners, anti-coagulants or preparing for a surgery. Due to their purgative action, some of these teas can lead to miscarriage. If you have your doctor’s approval and there’s nothing that could interfere with your treatment, choose a tea that fits you best and enjoy its wonderful benefits!... tea for water retention

Wild Carrot

Daucus carota. N.O. Umbelliferae.

Synonym: Bird's Nest.

Habitat: Wastes, pastures and field borders.

Features ? The branched stems of one to three feet high are tough and bristly. The whole plant is hairy, and the leaves are oblong and bipinnate, with acute segments. Blossoming in June and July, the umbel of white flowers usually contains one crimson flower in the centre. The root tapers, is yellowish-white, sweetish, and faintly aromatic. Wren tells us that "in taste and odour it resembles the garden carrot, but the root is small and white, not large." Ferrier, however, says of this root, "no resemblance in taste or colour to the cultivated carrot." Our own opinion is that Wild Carrot tastes like a rather distant relative of the household carrot—which it probably is.

Part used ? The whole plant.

Action: Pronouncedly diuretic in action, as well as de-obstruent and stimulant.

Wild Carrot naturally, therefore, takes a prominent place in many formulae for the treatment of dropsy, gravel, retention of urine, and bladder trouble generally. Either an infusion or decoction may be prepared in the usual proportions, and doses of 2 fl. ounces taken three or four times daily.

Culpeper comments ? "Wild Carrots belong to Mercury, and therefore breaketh wind, and removeth stitches in the sides, provoketh urine and women's courses, and helpeth to break and expel the stone."... wild carrot

Self Medication

The Government and health authorities of the UK and Europe express their desire that citizens take more responsibility for their own health. Also, the public’s disquiet towards some aspects of modern medicine leads them to seek alternatives elsewhere. As a generation of health-conscious people approach middle age, it is less inclined to visit the doctor but to seek over-the-counter products of proven quality, safety and efficacy for minor self-limiting conditions. This has the advantage of freeing the doctor for more serious cases. Intelligent self-medication has come to stay.

Prescriptions. While specimen combinations appear for each specific disease in this book, medicines from the dispensary may be varied many times during the course of treatment. The practitioner will adapt a prescription to a patient’s individual clinical picture by adding and subtracting agents according to the changing basic needs of the case. For instance, a first bottle of medicine or blend of powders may include a diuretic to clear the kidneys in preparation for the elimination of wastes and toxins unleashed by active ingredients.

The reader should never underestimate the capacity of herbal medicine to regenerate the human body, even from the brink of disaster.

Acknowledgements. I am indebted to my distinguished mentor, Edgar Gerald Jones, Mansfield, Nottinghamshire, England, to whom I owe more than I could ever repay. I am indebted also to the National Institute of Medical Herbalists, and to the British Herbal Medicine Association, both of which bodies have advanced the cause of herbal medicine. I have drawn heavily upon the British Herbal Pharmacopoeias 1983 and 1990, authentic publications of the BHMA, and have researched major works of ancient and modern herbalism including those pioneers of American Eclectic Medicine: Dr Samuel Thomson, Dr Wooster Beach, Dr Finlay Ellingwood and their British contemporaries. All made a vital contribution in their day and generation. I have endeavoured to keep abreast of the times, incorporating the latest scientific information at the time of going to press. For the purposes of this book I am especially indebted to my friend Dr John Cosh for checking accuracy of the medical material and for his many helpful suggestions.

A wealth of useful plants awaits further investigation. Arnica, Belladonna and Gelsemium are highly regarded by European physicians. It is believed that these plants, at present out of favour, still have an important role in medicine of the future. The wise and experienced clinician will wish to know how to harness their power to meet the challenge of tomorrow’s world.

Perhaps the real value of well-known alternative remedies lies in their comparative safety. Though largely unproven by elaborate clinical trials, the majority carry little risk or harm. Some have a great potential for good. The therapy is compatible with other forms of treatment.

The revival of herbal medicine is no passing cult due to sentimentality or superstition. It indicates, rather, a return to that deep devotion to nature that most of us have always possessed, and which seems in danger of being lost in the maze of modern pharmacy. It is an expression of loyalty to all that is best from

the past as we move forward into the 21st century with a better understanding of disease and its treatment. I believe the herbal profession has a distinguished and indispensible contribution to make towards the conquest of disease among peoples of the world, and that it should enjoy a place beside orthodox medicine.

Who are we to say that today’s antibiotics and high-tech medicine will always be available? In a world of increasing violence, war and disaster, a breakdown in the nation’s health service might happen at any time, thus curtailing production of insulin for the diabetic, steroids for the hormone-deficient, and anti-coagulants for the thrombotic. High-technology can do little without its specialised equipment. There may come a time when we shall have to reply on our own natural resources. It would be then that a knowledge of alternatives could be vital to survival. ... self medication

Arthritis, Gonococcal

A form of arthritis arising from infection by gonorrhoea may simulate rheumatoid arthritis, affecting the joint fluid. A history of genito-urinary discharge may confirm. Alternative formulae. Powders. Echinacea 2; Kava Kava 2; Prickly Ash 1; Cayenne quarter. Mix. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Tinctures. Balm of Gilead 1; Kava Kava 1; Black Cohosh half; Juniper quarter. Mix. Dose: 30-60 drops, thrice daily.

Topical. Tea Tree oil (if too strong may be diluted many times. Analgesic cream.

Treatment by or in liaison with a general medical practitioner or infectious disease specialist. ... arthritis, gonococcal

Arthritis, Infective

 Pyogenic. Bacterial infection may invade the body via mouth, nose or other mucous membranes. By the bloodstream it can be borne to almost any body tissues; joints of the shoulders, knees and hips. Immediate attention is necessary to avoid tissue destruction. Two virulent types are tuberculosis and gonorrhoea.

Infective arthritis may be associated with German Measles against which conventional antibiotics may be of little value. Infective organisms include: streptococcus, E. coli, staphylococcus, or others. May follow surgical operation, steroid therapy, rheumatoid arthritis or diabetes.

Symptoms. Joint hot, feverish, enlarged and painful.

Differential diagnosis: distinguish from gout and synovitis. Herbal treatment must needs be persevered with for 3 to 6 months, even longer. Good nursing is necessary. Natural life-style. Bedrest.

Treatment. For all microbial infections include Echinacea. (Hyde)

Teas. Nettles. Red Clover. Yarrow. 2 teaspoons to each cup boiling water; infuse 15 minutes. 1 cup 3-4 times daily.

Tablets/capsules. Devil’s Claw, Alfalfa, Echinacea, Horsetail.

Alternative formulae:– Powders. Echinacea 2; Burdock 1; Devil’s Claw 1; Guaiacum quarter. Mix. Dose: 750mg (three 00 capsules or half a teaspoon). Thrice daily.

Liquid Extracts. Echinacea 2; Juniper half; Black Cohosh half; Guaiacum quarter. Mix. Dose: 30-60 drops. Thrice daily.

Tinctures. Dandelion 2; Echinacea 2; Poke root half; Peppermint quarter. mix. Dose: 1-2 teaspoons. Thrice daily.

Above powders, liquid extracts and tinctures – effects are enhanced when each dose is taken in half-1 cup Fennel tea; otherwise, to be taken in water.

Topical. Analgesic cream. Comfrey poultice, Comfrey ointment. Tea Tree oil, Castor oil packs.

Diet. High Vitamin C foods. Dandelion coffee. ... arthritis, infective

Arthritis – Osteo

Osteo-arthritis. Erosion of cartilage of a joint with pain and stiffness. “Wear and tear” arthritis of the over 50s, affecting hands, knees, spine or hips. Biochemical changes in the cartilage stimulate overgrowth of bone cells (hyperplasia) which is an effort by the body to correct the disturbance.

Common in the elderly and menopausal women. Calcium salts may be laid down in a joint believed to be due to errors of diet. Small crystals of calcium hydroxyapatite have been observed to form in cartilage and synovial fluid. (Research group: St Bartholomew’s Hospital, London)

The aged sometimes suffer from diminished supply of hydrochloric acid in the stomach, and which is necessary for normal calcium metabolism. An effective substitute is 2 teaspoons cider vinegar in a glass of water sipped before or during meals.

Alte rnative s. Black Cohosh and Meadowsweet (natural sources of salicylic acid), Asafoetida (inflammation of connective tissue), Hawthorn (efficient circulation of the blood), Poke root, Bladderwrack, Guaiacum, Devil’s Claw, Bogbean, White Poplar bark, Yucca leaves.

Tea. Celery seeds. 1 teaspoon to each cup boiling water. Infuse 15 minutes. Half-1 cup, 2-3 times daily, before meals. Comfrey tea.

Alternative formulae:– Powders. White Willow 2; Devil’s Claw 1; Black Cohosh half; Guaiacum quarter. Mix. Dose: 500mg (two 00 capsules or one-third teaspoon). Thrice daily in water or Nettle tea. Liquid extracts. White Willow 2; Devil’s Claw 1; Bogbean 1; Fennel 1; Tincture Capsicum quarter. Mix. 1 teaspoon thrice daily in water or Nettle tea.

Tinctures. Bogbean 2; Meadowsweet 2; Black Cohosh 1; Guaiacum quarter; Peppermint quarter. Mix. Dose: 2 teaspoons thrice daily.

Tablets/capsules: Devil’s Claw, Wild Yam, Ligvites.

Cod liver oil. Chief of the iodised oils. Can reach and nourish cartilage by the process of osmosis. Its constituents filter into cartilage, imparting increased elasticity which prevents degeneration. Known to soften-up fibrous tissue. 2 teaspoons once daily. Also helps correct uric acid metabolism.

Topical. Physiotherapy. Osteopathy. Jojoba oil packs. Capsicum Cream. Hot and cold compresses twice daily – followed by a cold compress at night, leaving on when in bed. Hot Epsom salt bath twice weekly. Diet. Oily fish: see entry. Low fat. Low salt. High fibre. Avoid lemons and other citrus fruits. Lemon juice may remove some calculi from the body but later begins to remove calcium from the bones. Supplementation. Pantothenic acid 10mg; Vitamin A 7500iu; Vitamin B6 25mg; Vitamin E 400iu; Zinc 25mg.

General. Warm dry climate often relieves. Surgery may be necessary. Herbs Pleurisy root, Comfrey root and Bryonia, sustain the constitution and promote tissue healing after joint replacements with ceramic substitute after the famous Charnley operation. The condition is disabling but it is possible to manage successfully, maintaining normal activities with minimum difficulty. ... arthritis – osteo

Arthritis – Rheumatoid

A systemic inflammatory disease of several joints together where erosive changes occur symmetrically, and which may arise from inflammation and thickening of the synovial membrane. Cartilage becomes eroded and fibrous or even bony fusion leads to permanent fixation of a joint, or joints. Polyarthritis. An auto-immune disease.

Symptoms. Morning stiffness and pain wearing off later. Easy fatigue and decline in health. Nodules on surface of bones (elbows, wrists, fingers). Joint fluids (synovia) appear to be the object of attack for which abundant Vitamin C is preventative. Anaemia and muscle wasting call attention to inadequate nutrition, possibly from faulty food habits for which liver and intestine herbs are indicated.

Treatment. Varies in accord with individual needs. May have to be changed many times before progress is made. Whatever treatment is prescribed, agents should have a beneficial effect upon the stomach and intestines to ensure proper absorption of active ingredients. (Meadowsweet)

It is a widely held opinion that the first cause of this condition is a bacterial pathogen. An anti- inflammatory herb should be included in each combination of agents at the onset of the disease. See: ANTI-INFLAMMATORY HERBS. Guaiacum (Lignum vitae) and Turmeric (Curcuma longa) have a powerful anti-inflammatory action and have no adverse effects upon bone marrow cells or suppress the body’s immune system. Breast feeding cuts RA death rate.

Of therapeutic value according to the case. Agrimony, Angelica root, Balmony, Black Cohosh (particularly in presence of low back pain and sciatica), Bogbean, Boldo, Burdock, Celery, Cramp bark, Devil’s Claw, Echinacea (to cleanse and stimulate lymphatic system), Ginseng (Korean), Ginseng (Siberian), Liquorice, Meadowsweet, Poke root, Prickly Ash bark, White Poplar bark, White Willow bark, Wild Yam.

Tea. Formula. Equal parts. Alfalfa, Bogbean, Nettles. 1 heaped teaspoon to each cup boiling water; infuse 5-10 minutes, 1 cup thrice daily.

Decoction. Prickly Ash bark 1; Cramp bark 1; White Willow bark 2. Mix. 1oz to 1 pint water gently simmered 20 minutes. Dose: Half-1 cup thrice daily.

Tablets/capsules. Black Cohosh, Celery, Cramp bark, Devil’s Claw, Feverfew, Poke root, Prickly Ash, Wild Yam, Ligvites.

Alternative formulae:– Powders. White Willow bark 2; Devil’s Claw 1; Black Cohosh half; Ginger quarter. Mix. Dose: 750mg (three 00 capsules or half a teaspoon) thrice daily.

Liquid extracts. White Willow bark 2; Wild Yam half; Liquorice half; Guaiacum quarter. Mix. Dose: 1-2 teaspoons thrice daily.

Tinctures. Cramp bark 1; Bogbean 1; Prickly Ash half; Meadowsweet 1; Fennel half. Mix. Dose: 1-3 teaspoons thrice daily.

Ligvites. (Gerard House)

Cod Liver oil. Contains organic iodine, an important factor in softening-up fibrous tissue, to assist metabolism of uric-acid, help formation of haemoglobin, dilate blood vessels; all related to arthritics. The oil, taken internally, can reach and nourish cartilage by the process of osmosis; its constituents filter into cartilage and impart increased elasticity.

Topical. Evening Primrose oil, Wintergreen lotion, Comfrey poultice. Hydrotherapy: hot fomentations of Hops, Chamomile or Ragwort. Cold water packs: crushed ice or packet of frozen peas in a damp towel applied daily for 10 minutes for stiffness and pain. See: MASSAGE OIL.

Aromatherapy. Massage oils, any one: Cajeput, Juniper, Pine or Rosemary. 6 drops to 2 teaspoons Almond oil.

Supportives: under-water massage, brush baths, sweat packs, Rosemary baths, exposure of joints to sunlight.

Diet. Low salt, low fat, oily fish, Mate tea, Dandelion coffee. On exacerbation of the disease cut out all dairy products.

Supplements. Daily. Evening Primrose capsules: four 500mg; Vitamin C (1-3g); Bromelain 250mg between meals; Zinc 25mg.

General. Residence in a warm climate. Yoga. Disability and deformity may be avoided by a conscientious approach to the subject. ... arthritis – rheumatoid

Arthritis – Tuberculous

A chronic bone and joint condition due to bovine from of tuberculosis believed to be caused by drinking TB milk and cream. Mostly in children, beginning in fluids surrounding a joint before invading bone tissue. Instead of normal flesh colour a joint has a white appearance. Condition maybe secondary to disease of the lungs or glands. Pain worse at night.

Elecampane (Inula) has a direct effect on TB bacilli, controlling night sweats and localising the disease. Agents yielding salicylates (mild analgesics) Meadowsweet, White Willow, etc are of value. Echinacea increases phagocytic power of the leucocytes and may normalise percentage count of neutraphiles. To meet individual needs, it will be necessary to vary treatment many times during the course of the disease.

Alternatives. Echinacea, Elecampane, Balm of Gilead buds (Hyde), Gotu Kola, Comfrey root, Iceland Moss. Rupturewort promotes elasticity of lung tissue.

Decoction. Equal parts: Iceland Moss, Comfrey root, Elecampane root, Liquorice. Mix. 1oz to 1 pint water gently simmered 20 minutes in a covered vessel. Dose: Half a cup thrice daily.

Alternative formulae:– Powders. White Willow 2; Comfrey 1; Echinacea 1; Ginger quarter. Mix. Dose: 750mg (three 00 capsules or half a teaspoon) thrice daily.

Tinctures. White Willow 2; Echinacea 1; Blue Cohosh half; White Poplar half; Tincture Capsicum quarter. Mix. 1 teaspoon thrice daily before meals.

Tincture Krameria (Rhatany root), Dose: 30-60 drops in water thrice daily.

Fenugreek seed tea.

Comfrey. Potential benefit of Comfrey root outweighs risk.

Topical. Compresses: Mullein leaves, Lobelia, Comfrey root or Fenugreek. Evening Primrose oil. No massage to affected joints.

Diet. Low carbohydrate. Oily fish.

Supplements. Vitamins A, B6, B12, D, Niacin, Calcium, Iron, Phosphorus.

General. Tuberculosis is a notifiable disease for which specific medical treatment is available. Failure to comply may expose a practitioner to a charge of negligence. ... arthritis – tuberculous

Barberry Bark

Berberis vulgaris L. French: Vinettier. German: Berberize. Italian: Berberi. Indian: Zirishk. Stem bark.

Action. Liver stimulant, cholagogue, antiseptic, alterative. Tonic to spleen and pancreas, antemetic, digestive tonic. Hypotensive. Mild sedative and anticonvulsant. Uterine stimulant. Anti-haemorrhagic, Febrifuge, Anti-inflammatory, Anti-diarrhoeal, Amoebicidal, Bactericidal.

Uses: Sluggish liver, jaundice, biliousness, gastritis, gallstones, itching anus, ulcerated mouth, malaria, sandfly fever, toxaemia from drugs and environmental chemicals. Shingles, bladder disorders, leucorrhoea, renal colic. Old gouty constitutions react favourably. Cholera (animals). Leukopaenia due to chemotherapy.

Combinations. With Yarrow for malaria. With Gelsemium for pain in the coccyx (tailbone). With Fringe Tree bark for skin disorders.

Contra-indications: pregnancy, diarrhoea.

Preparations: Thrice daily.

Decoction: 1 teaspoon to each cup cold water left to steep overnight. Half-1 cup. Liquid Extract: BHP (1983) 1:1 in 25 per cent alcohol. Dose (1-3ml).

Tincture: BHP (1983) 1:10 in 60 per cent alcohol. Dose (2-4ml).

Powdered bark, dose, 1-2g. ... barberry bark

Bartram, John And William

18th century botanists who opened up the then American wilderness in search of medicinal and ornamental plants. They blazed a trail through hostile Indian territory in early pioneering days, bringing back plants to stock the first botanical garden in America. A knowledge of healing by medicinal plants and barks enabled these simple pious Quakers to render aid to other settlers and to the Indians from whom they learnt the art of healing. It is believed their activities would have been devoted exclusively to healing had they not received a commission from King George III to explore and report on the natural history of the country. The Bartrams’ talent in the practice of natural medicine impressed the Swedish explorer/botanist Peter Kalm who noted formulae in his diary.

The Bartrams’ friends included Benjamin Franklin and Washington who often visited their house, resting in the garden with giant trees planted by the Bartrams. John (1699-1777) was described by Linnaeus as the “greatest contemporary natural botanist”. His son, William, was also an explorer- naturalist and artist whose works are now collector’s pieces. ... bartram, john and william

Bearberry

Arctostaphylos uva-ursi, Spreng. French: Busserole. German: Gemeine Ba?rrentraube. Italian: Uva d’orso. Dried leaves.

Contains hydroquinones, iridoids, flavonoids. Keynote: highly acid urine.

Action. Diuretic, urinary antiseptic, astringent, haemostatic, oxytocic.

Uses: smarting cystitis, painful micturition, urethritis, blood in the urine, urinary retention, oedema of legs or face, bed-wetting, diarrhoea, dysentery, profuse menstruation, leucorrhoea (chronic).

Combinations. With Dandelion root for dropsy. With Broom, Buchu and Clivers for inflammation of urinary tract and bladder. With Couch Grass as a urinary antiseptic.

Soothing combination for kidney relief and renal backache: Bearberry 15 per cent, Couchgrass 15 per cent, Wild Carrot 15 per cent, Buchu 10 per cent, Alfalfa 45 per cent. Tea: 1 heaped teaspoon to each cup boiling water. Infuse 10 minutes, 1 cup twice daily.

Preparations: Thrice daily.

Tea. 1 heaped teaspoon to each cup boiling water; infuse 15 minutes; Dose: half-1 cup.

Liquid extract BHC Vol 1. 1:1, in 25 per cent ethanol. Dose: 1.5-2.5ml.

Tincture BHC Vol 1. 1:5. in 25 per cent ethanol. Dose: 2-4ml.

Powder. 250mg. (One 00 capsule or one-sixth teaspoon).

Tablets. Popular combination. Powdered Dandelion root BHP (1983) 90mg; powdered Horsetail extract 3:1 10mg; powdered Uva Ursi extract 3:1 75mg. To assist urinary flow and prevent fluid retention. Precautions. Not used in pregnancy, kidney disorders, lactation. Large doses may cause vomiting. Should not be used for more than two weeks without consulting a practitioner. ... bearberry

Betony

Wood Betony. Stachys betonica. Betonica officinalis L. German: Betonien. French: Be?toine. Spanish: Beto?nica. Italian: Betonica. Dried herb.

Action: Affinity for liver and nervous system. General tonic (emphasis on circulation of the brain). Bitter. Stomachic, Sedative (mild).

Uses: Headache, nervous debility, lack of energy, loss of memory, weak digestion, sciatica, chronic rheumatism, sinus congestion, temporal arteritis (temporary relief), dizziness, hiatus hernia, low back pain (to reduce). Myalgic encephalomyelitis (ME). Nightmare.

Combinations. With Valerian for anxiety states. With equal parts Agrimony and Raspberry leaves as a substitute for domestic tea. With Vervain to enhance its relaxing properties.

Caution. Avoid over-dosing in pregnancy.

Preparations: Tea: 1-2 teaspoons to cup boiling water; infuse 5-10 minutes. 1 cup freely. Liquid Extract: 1 teaspoon in water.

Tincture BHP (1983) 1 in 5 in 45 per cent alcohol. Dose 30-90 drops (2-6ml). ... betony

Bryony, White

Wild vine. Bryonia alba L. French: Bryone blanche. German: Zaunru?be. Spanish: Brionia. Italian: Briona bianca. Contains cucurbitacins. Sliced dried root.

Action: diaphoretic, expectorant, powerful hydragogue, emetic, cathartic, anti-tumour, anti-rheumatic. Externally: as a rubefacient. Internal use, practitioner only.

Uses: Rheumatism worse from movement, rheumatic fever, acute arthritis. Heart disorder following rheumatic fever. For absorption of serous fluid as in pleurisy. Congested bronchi and lungs. Synovitis, malaria and zymotic diseases.

Combinations: With Black Cohosh for muscular pain. Also for tenderness of the spinal vertebre (an important indication). With Poke root for inflammation of the breast or testicles.

Preparations: Owing to difficulty of the layman to dispense accurately dosage of powder or decoction, use is best confined to liquid extract or tincture; small doses frequently repeated; large doses avoided. Liquid Extract: 10 drops in 4oz water; dose 1 teaspoon every half hour.

Tincture: dose; 2 teaspoons every half hour (acute) cases; thrice daily (chronic).

External. Tincture used as a lotion.

Note: Not used in pregnancy, lactation or in presence of piles. ... bryony, white

Buchu

Bucco. Barosma betulina. Agathosma betulina (Berg). French: Buchu. German: Bukkostrauch. Spanish: Buchu. Italian: Diosma. Dried leaves.

Action: promotes secretion of urine. Stimulant diuretic (cold). Safe and effective anti-bacterial for urinary tract infections and recurrent inflammation of the bladder.

Keynote: urinary antiseptic.

Constituents. Volatile oil, flavonoids, tannin, mucilage, B-complex vitamins.

Uses: Cystitis, especially when caused by organism E. Coli. Pyelitis, urethritis, prostatitis, pus in the urine. Catarrh of the bladder. Fluid retention. To aid flow of urine.

Popular kidney herbs. Tea. Couchgrass 25 per cent; Buchu 15 per cent; Bearberry 15 per cent; Alfalfa 45 per cent. 1-2 teaspoons to cup boiling water.

Combinations. Teas. (1) equal parts: Buchu, Uva Ursi, Broom and Clivers; for chronic dropsy. (2) equal parts: Buchu and Juniper berries, for acute dropsy. (3) equal parts: Buchu and Marshmallow for irritable bladder.

Side effects – none known.

Preparations: Minimum heat. Should not be boiled. Covered vessel (teapot) to prevent escape of volatile oil. Thrice daily.

Tea: One teaspoon to each cup boiling water; infuse 15 minutes. Half-1 cup.

Liquid extract, BHC Vol 1. 1:1 90 per cent ethanol. Dose: 0.5-1.5ml.

Tincture, BHC Vol 1. 1:5, 60 per cent ethanol. Dose: 2-4ml.

Infusion Buchu Cone BPC 1954. 1:2.5, 25 per cent ethanol. Dose: 4-8ml.

Kasbah Remedy (Potter’s). Buchu an important ingredient.

Gerard House. Formula. Pulverised Dandelion root 60mg; Pulverised Extract Buchu 3-1, 20mg; Pulverised Extract Uva Ursi 3-1, 20mg; Pulverised Extract Clivers 4-1, 4mg. Dose: 2 tablets thrice daily. ... buchu

Bugleweed

Water horehound. Gipsywort. German: Gemeiner Wolfstrapp. French: Lycope. Italian: Licopo. Lycopus europaeus and Lycopus virginicus. Properties of both plants are the same. Dried herb. Action: “cardio-active diuretic, increasing force of myocardial contraction and reducing heart rate” BHP (1983). Palpitation, peripheral vasoconstrictor, antitussive, hypoglycaemic, sedative, anti-haemorrhagic, thyrostatic, narcotic (mild).

Mild contraceptive containing lithospermum acid which blocks gonadotropic hormones of the anterior pituitary (Rudolf F. Weiss MD)

Uses: To reduce rapid heart beat from over-active thyroid. Reduces high pulse rate in thyrotoxicosis with heart involvement. Raises blood sugar levels in diabetes. Internal haemorrhages, bleeding from the lungs, menorrhagia. High blood pressure.

Combinations. With Lily of the Valley (Bugleweed 2; Lily 1) for heart cases. With Elecampane (equal parts) for cough of tuberculosis. With Valerian 1 for thyrotoxicosis.

Preparations: Thrice daily.

Tea: 1 heaped teaspoon to each cup boiling water; infuse 10 minutes. Dose: half-1 cup. Tincture BHP (1983) 1 part to 5 parts 45 per cent alcohol. Dose: 2-6ml in water. ... bugleweed

Bush Tea

See: ROOIBOSCH TEA.

BURSITIS. Tendinitis. Inflammation of a bursa – a soft-tissue elastic sac between bones that glide over one another, as in elbow and shoulder. Contains a little fluid, its purpose being to form a cushion against friction. In the knee-joint it is known as ‘housemaid’s knee’; over the hips as ‘weaver’s bottom’, joints becoming red, hot and painful.

Deposits of calcium may thicken walls and form a focus of pressure, causing pain. Relief comes when the swelling disperses or bursts. In the 60-70 age group rupture of tendons is a frequent cause. Bursitis accounts for two-thirds of shoulder pains. Neglected, it may progress to ‘frozen shoulder’ in later life. Teas. Celery seeds, Comfrey leaf, Nettles, Wintergreen.

Tablets/capsules. Prickly Ash, Lobelia, Wild Yam, Helonias.

Alternative formulae:– Powders. Turmeric 2; Prickly Ash 1; Cayenne quarter. Mix. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Liquid extracts. Equal parts: Black Cohosh, Devil’s Claw, Turmeric. Mix. Dose: 30-60 drops thrice daily.

Tinctures. White Willow bark 2; Prickly Ash bark 1; Wild Yam 1; Capsicum quarter. Mix. Dose: 2 teaspoons thrice daily.

Cider vinegar. 2-3 teaspoons to glass of water 2-3 times daily.

Topical. Apply strapping plaster to arrest swelling. See: FOMENTATIONS. POTATO. BRAN OR COMFREY ROOT POULTICE.

Aromatherapy. Cajeput, Chamomile, Origans, Rosemary. 6 drops of any one oil in 2 teaspoons Almond oil for massage.

Diet. See: DIET – GENERAL.

Supplements. Vitamin A. Vitamin C (3-4g). Vitamin E (400iu). Zinc 15mg.

General. Cold packs. Compression bandages. Gentle massage under the knee where knee joint is involved. For septic bursa add Echinacea to internal medication or apply ointment. For drainage, aspiration is sometimes necessary. Protect knees with knee-pads. Turmeric acquires reputation for relief. ... bush tea

Butternut

White Walnut. Juglans cinerea L. French: Noix de beurre. German: Butter Walnuss. Italian: Noce cenerino. Root bark and leaves.

Action: cholagogue, hepatic, laxative, blood tonic, anthelmintic, reputed anti-tumour.

Uses: Chronic constipation associated with liver disorder. To increase flow of bile and its release from the gall bladder. Toxic liver disorder. Skin diseases with pus. Worms in children. Piles.

Combinations. (1) equal parts, with Yellow Dock and Burdock for chronic skin disorders. (2) with Figwort 2; Butternut 1; for piles. (3) equal parts with Mugwort for worms.

Preparations: Thrice daily.

Decoction. Half a teaspoon to each cupful water gently simmer 15 minutes. Dose, half-1 cup.

Liquid Extract. 2 to 4ml in water. ... butternut

Cardiac Dropsy

Dropsy of heart origin is distinguished from renal dropsy by an increase in oedema as the day proceeds. In the morning there may be no swelling but by the evening legs become swollen from the ankles upwards. Fluids stagnate in the tissues from inability of the heart to perform efficiently as a pump. The condition is a symptom of heart failure with increasing breathlessness which may lead to general dropsy.

Symptoms: worse after exercise, breathlessness, headache, general weakness, feeble pulse, pale face, skin cold, swollen tissues pit on pressure.

Treatment. Alternatives:– Teas. Black Cohosh, Broom tops, Buchu, Dandelion, Hawthorn, Parsley root. Tea. Formula. Equal parts: Broom tops, Motherwort, Yarrow. 2 teaspoons to each cup water brought to boil and simmered 5 minutes in covered vessel. 1 cup 3-4 times daily.

Tablets/capsules. Buchu, Dandelion, Hawthorn, Juniper, Motherwort.

Formula. Dandelion 2; Hawthorn 2; Stone root 1. Mix. Dose: Powders: 750mg (three 00 capsules or half a teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Thrice daily.

Practitioner. Lily of the Valley, BPC 1934: 5-20 drops, 2-3 times daily.

Squills, tincture: resembles Digitalis in action. Dose: 1-3 drops, as prescribed.

Tinctures. Dandelion 2; Lily of the Valley 2; Stone root 1; Cayenne (tincture) quarter. Mix. Dose: 1 to 2 teaspoons thrice daily.

Popular formula. Tincture Scilla 5.0; Tincture Crataegus 10.0; Tincture Valerian to make 30.0. 15 drops thrice daily. (German Extemporaneous Formulae)

Diet. High protein. See: DIET – HEART AND CIRCULATION. ... cardiac dropsy

Chamomile Flowers (german)

Wild Chamomile. Matricaria recutita L. German: Hundskamille. French: Camomille. Italian: Camomilla. Spanish: Camomile. Part used: flowerheads. Contains chamazulene which is active against staphylococcus aureus.

Constituents: volatile oil, flavonoids, tannic acid.

Action. Anti-inflammatory, antimicrobial, antiseptic (mild), anti-peptic ulcer, anodyne (mild), antispasmodic, bitter, carminative, vulnerary. Mild nerve sedative but tonic to the alimentary canal.

Uses: Internal use. Nervous excitability, convulsions, restlessness, hyperactivity in children, insomnia, early stages of fever, measles (warm tea), travel sickness, pin and thread worms, peptic ulcer, gastro- intestinal spasm – calms down digestive system, pre-menstrual tension, hysteria from womb irritation, Candida albicans, inflammation of respiratory and gastro-intestinal tracts, sore throat and mouth. Psychosomatic illness: see CHAMOMILE ROMAN. May be used in pregnancy.

External use. “Inflammation and irritation of skin and mucosa, including the oral cavity and gums, respiratory tract and anal and genital area.” (EM) Conjunctivitis (cold tea). Gangrene (poultice with few drops Tincture Myrrh).

Combinations. With Valerian, Passion flower and Hops (equal parts) for nervous excitability. With Liquorice 1 and Chamomile 4 for gastric ulcer and chronic dyspepsia. Chamomile works well with Peppermint and Balm; equal parts.

Preparations: One teaspoon to each cup boiling water; infuse 5-10 minutes; one cup freely. Powder. Quarter to half a teaspoon; tablets/capsules.

Liquid extract BHC Vol 1. 1:1 in 45 per cent ethanol. Dose: 1-4ml (15-60 drops). Tincture. 1 part to 5 parts 45 per cent alcohol. Dose: 5-10ml (1-2 teaspoons).

Oil of Chamomile. Prepare as for OILS – IMPREGNATED.

Essential oil (Aromatherapy). Externally for neuralgia.

Compress: See: CHAMOMILE FLOWERS, ROMAN. Rinses. Gargles.

Chamomile bath. Add strong infusion to bath water for irritable skin rash, eczema.

Chamomile enema. 1 tablespoon flowers in 2 litres (3 and a half pints) boiling water; infuse, strain and inject warm.

Side-effects: rare contact skin allergy. ... chamomile flowers (german)

Catarrh

Inflammation of the mucous membrane (lining membrane) which becomes boggy and discharges excessive mucus. Aetiology: infection, allergy or toxaemia. May arise from lack of fresh air, stagnant atmosphere, irritation by dust, inflammation of the middle ear, tonsils or nasal sinuses, but chiefly from auto-toxaemia when it is a natural reaction to toxic matter – an effort to expel through the mucous membrane wastes that would otherwise leave the body via the skin, kidneys or bowel. Constipation worsens the condition.

It is often caused by a heavy intake of starches, salt, sugar, white flour products, and especially dairy products including milk. Some cases are due to poor diet, low blood calcium, vitamin and mineral deficiency. May manifest as catarrh of the nose, throat, stomach, bowels, bronchi or bladder. Alternatives:–Teas made from any of the following: Angelica, Avens, Coltsfoot, Comfrey leaves, German Chamomile, Elderflowers, Eyebright, Garlic, Ginseng, Gotu Kola, Ground Ivy, Hyssop, Marshmallow leaves, Mullein, Mouse-ear, Parsley, Plantain, Marsh Cudweed, White Horehound, Yarrow.

Garlic. Good results reported.

Traditional combination. Equal parts, herbs: Angelica, Eyebright, Yarrow. 1 heaped teaspoon to each cup of boiling water.

Fenugreek seeds. 2 teaspoons to each cup water simmered 5 minutes; 1 cup thrice daily. Or grind to a powder in a blender to sprinkle on salads or cereals.

Tablets/capsules. Garlic, Iceland Moss, Lobelia, Poke root, Goldenseal (Gerard). Horseradish and Garlic (Blackmore).

Tinctures. Alternatives. (1) Goldenseal: 3-5 drops. Formulae: (2) Angelica 2; Ginger 1. (3) Lobelia 1; Goldenseal 1; Juniper 1. One teaspoon – thrice daily.

Tincture Myrrh, BPC 1973. 3-5 drops in water thrice daily.

Tea Tree oil. 2-3 drops on teaspoon honey, or in water, thrice daily.

Heath and Heather Catarrh pastilles. Squills, Menthol, Pine oil, Eucalyptus oil.

Antifect. (Potter’s) Germicidal for blocked sinuses, etc.

Eric Powell. Liquid extracts: Angelica 1oz; Juniper 1oz; Peppermint half an ounce; Root Ginger half an ounce. 1-2 teaspoons in water thrice daily.

BHP (1983). (Bronchial) Irish Moss, Cinnamon, Liquorice.

Gargle. 3 drops Tincture Myrrh in half glass water.

Inhalation. Small handful Chamomile flowers or Eucalyptus leaves to 2 pints boiling water in washbasin. Cover head with towel and inhale 10 minutes. Or – see: FRIAR’S BALSAM.

Aromatherapy. Essential oils, diluted with 20 parts water, as injection for nasal catarrh: Eucalyptus, Thyme, Pine, Garlic, Hyssop, Tea Tree.

For catarrh of the womb and vagina: see LEUCORRHOEA.

Diet. Refer: GENERAL DIET. Commence with 3-day fast.

Supplementation. Vitamins A and D as in Cod Liver oil. Vitamins B-complex, C and E.

General. Cold sponge-down, deep-breathing exercises. Sea-bathing. Smoking promotes congestion.

Note: However inconvenient, catarrh has one useful protective role – it helps prevent bacteria and toxins reaching tissue. For instance, when present in the nasal organs it may prevent mercury vapour from teeth- amalgam reaching the brain. ... catarrh

Chaparral

Creosote bush. Grease bush. Larrea divaricata. Leaves.

Action. Antibiotic, powerful blood cleanser, bactericidal, anti-inflammatory, alterative, respiratory and urinary antiseptic, anti-oxidant, anti-psoriasis, anti-arthritic. Contains NDGA a powerful parasiticide. Anti-tumour, anti-microbial. Strong bitter, enzyme inhibitor. All body cells feel its influence. Of low toxicity.

Uses: Regarded as a ‘cure-all’ by the Arizona Indians. Rheumatism, arthritis, skin disorders, bursitis, lumbago, healing of external wounds, delayed menses, indigestion, kidney disorders, piles, tetanus, itching. Early American agent for sexually transmitted diseases. History of use in skin malignancy. Chronic chest complaints (tea).

Combinations. (1) Combines well with antibiotics: Goldenseal 1; Echinacea 2; Chaparral 3. (2) Combines with Sarsaparilla (equal parts) for venereal infections and chancre. (Dr J.M. Bigelow) Preparations. Best uses reported from tea or tablets.

Tea: daily bitter health beverage; half a teaspoon to each cup boiling water; infuse 15 minutes. Half-1 cup, thrice daily.

Tablets/capsules: one 150mg thrice daily.

Ointment. 1oz powdered herb to 16oz suet. Steep one hour in an oven 300-350 degrees F. Strain through sieve; pour into jar.

Note: The sale of Chaparral has been banned in the United States of America and the United Kingdom as a result of reported cases of human toxicity. ... chaparral

Charcot’s Disease

Neurogenic arthritis. A degenerative and destructive joint lesion due to loss of the normal protection and pain sense. It is associated with tabes dorsalis and syringomyelia. In tabes, knee is chiefly affected; in syringomyelia, the elbow. Joint swelling in late locomotor ataxia. Usually painless.

Alternatives. Cramp bark, Cayenne, Chamomile, Guaiacum, Hops, Meadowsweet, Celery, Prickly Ash, Valerian, Wild Lettuce, Wild Yam. Mistletoe (F. Hyde). White Willow.

Tea. Equal parts: German Chamomile, Hops, Meadowsweet. 1 heaped teaspoon to each cup boiling water; infuse 5-10 minutes; 1 cup 3 or more times daily.

Tablets/capsules. Chamomile, Mistletoe, Prickly Ash, Ligvites, Wild Yam, Valerian, Kelp.

Alternative formulae:– Powders. Prickly Ash 1; Valerian 1; Cramp bark half; Guaiacum quarter. Mix. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Liquid Extracts. White Willow 2; Prickly Ash 1; Celery seeds half; Liquorice quarter; Tincture Capsicum quarter. Mix. 30-60 drops thrice daily.

Tinctures. White Willow 2; Prickly Ash 1; Valerian 1; Meadowsweet 1; Tincture Capsicum quarter. Mix. 2 teaspoons thrice daily.

Topical. Comfrey poultices (Maria Treben). “Three oils.”

Diet. Lacto-vegetarian. Dandelion coffee. Oily fish.

General. Straight knee brace for rigid support. ... charcot’s disease

Cola

Kola seeds. Cola nitida. Cola acuminata. German: Kolabaum. French: Cafe? du Soudan. Spanish: Kola. Italian: Noci del sudan. Malayan: Kelapong. Part used: dried powdered seeds. Constituents: Caffeine, theobromine, kolanin, gum, tannic acid, phenols.

Keynote: cerebro-spinal stimulant.

Action: Nerve tonic, anti-depressant, diuretic, astringent, anti-diarrhoeal. Thymoleptic BHP (1983). Strengthens action of the heart by increasing its muscular power. Antidepressant. Stimulates the central nervous system and strengthens the heart by increasing its muscular power.

Uses: Physical and mental exhaustion (jet-lag), brain fatigue, neurasthenia, convalescence, muscle weakness, headache, depression. Diarrhoea, dysentery. Contains caffeine which increases mental alertness, heart rate and passage of urine. Low blood pressure. Not given in presence of high blood pressure.

Traditional combinations: (1) with Damiana and Saw Palmetto for sexual weakness. (2) with Skullcap and Oatstraw for depression and nerve debility.

Burroughs and Wellcome (1900) issued a tabloid “Forced March” (Kola compound 5g) used during the South African war and continued until 1937. Today similar preparations exist for jet-travel and tired business-men.

Side-effects: over-excitability.

Preparations: Average dose: 1 to 3 grams. Thrice daily.

Decoction (powder). Half a teaspoon to each cup water gently simmered 10 minutes. Dose 1 cup. Powder/tablets: 1 to 3g.

Liquid Extract, BHC Vol 1. 1:1, 60 per cent ethanol. Dose: 0.6 to 1.2ml.

Tincture BPC (1934). 1:5 in 60 per cent alcohol. Dose: 1-4ml. ... cola

Colds

The common cold. A virus droplet infection of the air passages.

Symptoms: Red itching eyes, clear nasal discharge progressing to yellow and thick, slight sore throat, sneezing, mild fever, headache, blocked or running nose, malaise.

The alternative school of medicine believes a cold should not be suppressed with popular drugs of the day but allowed to run its course. That course may be dramatically reduced by use of herbs. A cold is sometimes an acute healing crisis in which Nature expels accumulated wastes and toxins. Diaphoretics promote sweating, aiding this process.

Alternatives. Teas may be made from any of the following: Elderflowers, Peppermint, Catmint, Bayberry, Boneset, White Horehound, Feverfew, St John’s Wort.

Alternatives. Formulae:– Equal parts:– (1) Elderflowers and Peppermint. (2) Yarrow and Peppermint. (3) White Horehound and Hyssop. 1 teaspoon to each cup boiling water; infuse 5-15 minutes. 1 cup freely. A trace of Cayenne Pepper enhances potency and stimulates circulation.

Decoction. Prepared from Horseradish, Pleurisy root, Prickly Ash, Bayberry. Teaspoon, of any one, to two cups water gently simmered 20 minutes. Half-1 cup freely. Pinch of Cayenne enhances action.

Irish Moss. 1 teaspoon to 2 cups water simmered gently 20 minutes. Do not strain. Eat with a spoon with honey.

Powders. Composition. 1 teaspoon to cup of tea, or hot drink.

Powders. Formula. Bayberry bark 2; Ginger 1; Pleurisy root 1. Cayenne quarter. Sift. 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Tablets/capsules. Lobelia. Iceland Moss. Vitamin C. Feverfew.

Essence of Cinnamon. Popular traditional herbal expectorant to help relieve symptoms of cold and flu. Composition essence and Elderflowers and Peppermint. 2 teaspoons in hot water or cup of tea every 3 hours. Children less according to age.

Life Drops. See entry.

Practitioner. Colds with fever, cardiac excitability and distress out of all proportion to the infection: Tincture Gelsemium, 3-5 drops.

Laxative. A mild laxative may be advised (5-7 Senna pods, infused in cup of boiling water, or Senacot). A healthy bowel movement may cut short a cold by assisting elimination.

Aromatherapy. Few drops of any of the following antiseptic oils added to a bowl of boiling water, head covered with a towel, steam inhaled: Eucalyptus, Peppermint, Marjoram, Thyme, Niaouli. Oil of Camphor is most effective, but as it antidotes all other medicaments, should be used alone. Oil of Scots Pine (5-10 drops) used in bath. Tiger Balm. Olbas oil.

Diet. 3-day fast; no solid food, herb teas and fruit juices only. Citrus fruits (Vitamin C) in abundance. Hot lemon and honey.

Supplementation. Daily. Vitamin A (7500iu), B-complex (50mg), C (3 grams at onset: 2 grams every 3 hours thereafter).

Prophylaxis, winter months. Daily: Vitamin C (Rose Hip, Acerola, etc), Echinacea. 2 Garlic capsules at night to build-up body’s resistance. ... colds

Cold Sore

See: HERPES SIMPLEX.

COLI BACILLUS. Infections. Freshly-grated Horseradish root steeped in cup cold water for 2 hours.

Remove root. 1 cupful freely, as tolerated. Papaya fruit.

COLIC. Spasm of the bowels, particularly the colon. Severe pain under the navel with nausea, vomiting.

Patient writhes from side to side. Cause may be wind, acid bile, worms, constipation, food; aluminium, lead or other metal poisoning, strangulated hernia, appendicitis, adhesions.

Differential diagnosis: gallstones, menstrual difficulties, kidney stone.

Alternatives. Teas, any one. Roman Chamomile, Catmint, Fennel, Lovage, Caraway, Betony, Avens, Wormwood, Holy Thistle, Peppermint leaves, Aniseed, Tormentil.

Decoction, any one. Angelica root, Boldo, Calamus, Cardamom, Condurango, Coriander, Cramp bark, Ginger root, Liquorice, Wild Yam.

Tablets/capsules. Dandelion, Capsicum, Valerian, Wild Yam, Cramp bark, Blue Flag root.

Powders. Alternatives. (1) Calamus 2; Marshmallow root 1. Add pinch Cayenne. (2) Turkey Rhubarb plus pinch of Cayenne. (3) Wild Yam plus pinch of Cayenne. Dose: 500mg (one-third teaspoon or two 00 capsules) every 2 hours.

Tinctures. Formulae. Alternatives: (1) Angelica root 1; Wild Yam 1; Ginger half. Mix. (2) Dandelion 2; Wild Yam 1; few drops Tincture Capsicum. Mix. (3) Wild Yam 1; Galangal root half; Ginger half. Mix. Dose: 1 teaspoon in hot water every 2 hours.

Traditional German combination. Ginger, Gentian, Turkey Rhubarb.

Topical. Apply hot bran, oats, hops or Slippery Elm poultice, or Castor oil packs to abdomen. Aromatherapy. Any one oil: Aniseed, Fennel, Mint, Garlic, Bergamot. Adult: 6 drops to 2 teaspoons Almond oil: child, 2 drops in 1 teaspoon Almond oil, for abdominal massage.

Enema. 1oz Catmint, Boneset or Chamomile in 2 pints boiling water. Strain, inject warm.

Diet. 3-day fast, with fruit juices and herb teas.

See: RENAL COLIC, COLIC OF PREGNANCY, CHILDREN. Gripe water. ... cold sore

Constipation

Failure of contents of the large bowel to be evacuated due to inactivity, chemical laxatives, ignoring body signals that the body is full, obsession with bowel movements, piles, diverticulosis with small pockets from the colon, lack of exercise, spastic condition, low-fibre foods, poor eating habits, nervous stress. Waste products stagnate, changing behaviour of intestinal flora friendly to the body and necessary for breakdown of food. Toxins formed from reabsorption may be the cause of chronic disease.

Constipation is usually due to an underlying condition which requires primary treatment: i.e. anaemia.

The habit of taking purgatives lessens ability of the bowel to do its work. Gentler-acting remedies are advised: Isphagula (Psyllium seeds, light). In prescriptions, it is good practice to include a remedy for the liver (Barberry, Wahoo) and the digestive system (Dandelion, Liquorice). For constipation of pregnancy – see PREGNANCY.

Alternatives. Senna. 1-2 teaspoons leaves or 5-7 pods to cup cold water left to stand overnight. Combined tea. Equal parts: Senna leaves, Chamomile flowers, Fennel seeds. 1-2 teaspoons to each cup boiling water; infuse 15 minutes. 1 cup, evening.

Psyllium seeds (Ispaghula, pale) 1, 2, 3 or more teaspoons aided down with sips of water, morning or evening.

Decoctions. Any of the following: Black root, Blue Flag, Buckthorn, Cascara sag, Dandelion root, Turkey Rhubarb, Wahoo, Yellow Dock.

Tablets/capsules. Dandelion. Calamus. Blue Flag. Seaweed and Sarsaparilla. Turkey Rhubarb. Damiana. Senokot.

“Natural Herb Tablet”: Holy Thistle 60mg; Aloes BP 50mg; Fennel powder BPC 15mg; Myrrh powder BPC 15mg; Extract Skullcap 10mg; Powdered Valerian BPC 30mg; Powdered Lime flowers BPC 1949 30mg. Two or more tablets as necessary. Variations of this formula are on sale throughout Europe and the UK.

Powders. Combinations. Alternatives. (1) Turkey Rhubarb, with trace Cayenne. Use powder, or rubbed Rhubarb root with aid of kitchen grater.

(2) Equal parts: Barberry, Liquorice, Senna pods.

(3) Turkey Rhubarb 6; Slippery Elm 1; Liquorice 1. (4) Senna 70; Buckthorn 5; Fennel 10; Mate 5; Elder 5; Psyllium (pale) 5. Dose: 500-750mg (2-3 00 capsules or one-third-half a teaspoon) once or twice daily, as necessary.

Tinctures. Formulae: (1) Turkey Rhubarb, with trace of Capsicum. (2) Dandelion 2; Cascara sag, 2; Barberry 2; Liquorice 1; Tincture Ginger half. Half-2 teaspoons in hot water, evening.

Standard sales. A large number of preparations are on sale including Potter’s “Lion Cleansing Herbs”, Monastery herbs, Priory herbs. Fybogel Orange to increase bulk in colon. Regulan, for high fibre regimen. Enema or gravity douche: half an ounce Chamomile flowers to 2 pints boiling water allowed to cool. Inject warm; repeat twice weekly until normal function is established.

Diet. Milk-free diet often curative. Teaspoon powdered Agar Agar with meals once or twice daily. Prunes soaked overnight. Yoghurt. Crude black molasses. Increase fibre-foods. Dandelion coffee.

Hay Diet. Impressive results reported.

Supplementation. Cod Liver oil.

Vitamins: A. B-complex, Thiamine, Niacin, C. P (bioflavonoids). Minerals: Calcium. Potassium. Zinc. ... constipation

Diarrhoea

The world’s biggest killer of children. Inflammation of the bowel by production of too much mucous secretion.

Causes: faulty absorption of fats, bacterial or viral infection, nervous bowel, anxiety or psychosomatic disturbance, malfunction of the thyroid gland, etc.

Looseness of the bowels may sometimes occur as an acute cleansing eliminative effort by Nature to expel wastes and impurities. Dehydration can be serious in children. For presence of mucous or blood in the stool refer to DIFFERENTIAL DIAGNOSIS.

Differential diagnosis. Crohn’s disease, Gastroenteritis, Diverticulosis, Ulcerative colitis, Dysentery, Salmonella.

Travel diarrhoea: ‘blight of holiday and business trips abroad’ due to E. Coli. Acute, usually non- persistent self-limiting condition. Ginger, crystallised or powder in capsules or tablets is known to reduce the incidence in high risk areas.

Imported bloody diarrhoeas – salmonella, shigella or amoebic infections should receive special investigation by a competent authority, a consultant in infectious diseases. First-aid until the practitioner comes: 2-5 drops oil of Peppermint in water.

Children’s diarrhoea. Re-hydration after severe loss of fluids – glass of water containing 1 teaspoon salt and 2 teaspoons sugar.

Over 13,000 children die from this preventable disease every day, many in the developing countries. This simple combination of sugar and salt prevents dehydration, the most common cause of death from acute diarrhoea, and has helped save tens of thousands of lives.

Alternatives. Rest. Avoid caffeine and alcohol drinks. Plenty of astringent herb teas to reduce the associated hyperperistalsis. Children – half-dose.

Teas. Any one of the following: Agrimony, Avens, Burmarigold, Black Walnut leaves, Burnet (greater or garden), Ground Ivy, Ladysmantle, Hops (nervous bowel), Plantain, Peppermint, Periwinkle (vinca major), Meadowsweet, Silverweed, Shepherd’s Purse, Tormentil. Sage. Formulae: (1) equal parts; Raspberry leaves, Agrimony, Avens. Or (2) equal parts; Raspberry leaves, Plantain, Silverweed. 2 teaspoons to each cup boiling water; infuse 5-15 minutes. Half-1 cup freely. For nerve exhaustion: add a sprinkle of Valerian.

Seeds. Coriander, Caraway or Fenugreek. Half a teaspoon to each cup water, brought to boil; vessel removed as soon as boiling point is reached. Half-1 cup freely.

Decoctions. Any one of the following: Bayberry, Cranesbill (American), Rhatany root, Sweet Chestnut leaves, Oak bark, Wild Yam, Iceland Moss.

Powders. Any one: Calamus, Bayberry, Oak bark, Cinnamon, Black Catechu, Wild Yam. Add pinch of Ginger.

Tinctures. (1) Combine Bayberry 2; Ginger 1. Or (2) Combine Bayberry 1; Raspberry leaves 2. One to two 5ml teaspoons thrice daily after meals.

Tincture, or spirits of Camphor: 5-10 drops in water every 3-4 hours for severe depletion of body fluids. Adults only.

Aloe Vera. Scientific papers confirm efficacy.

Dr Finlay Ellingwood. Castor oil: 5 drops every 2 hours.

Bilberry juice. Half-1 cup freely.

Goldenseal. Antibacterial. 5-10 drops, tincture, 3-4 times daily. Adults only.

Diet. Avoid cow’s milk. 3-day fast on fruit juices and herb teas alone, followed by gruel made from Slippery Elm, Oatmeal or Arrowroot. Yoghurt. Bilberry fruit. Carob bean products: chocolate or other preparations. Ensure adequate fluid intake.

Supplementation. Vitamins A, B12, C, D. Minerals: Calcium, Iron, Magnesium, Potassium, Zinc. Preventative. 2 drops oil of Peppermint morning and evening. ... diarrhoea

Drug Dependence

One third of those taking tranquillisers become addicted. One of the problems of psychological dependence is the discomfort of withdrawal symptoms.

Symptoms. Tremors, restlessness, nausea and sleep disturbance. The greater potency of the drug, the higher the rebound anxiety. Many drugs create stress, weaken resistance to disease, tax the heart and raise blood sugar levels.

Drugs like Cortisone cause bone loss by imperfect absorption of calcium. Taken in the form of milk and dairy products, calcium is not always absorbed. Herbs to make good calcium loss are: Horsetail, Chickweed, Slippery Elm, Spinach, Alfalfa.

Agents to calm nerves and promote withdrawal may augment a doctor’s prescription for reduction of drug dosage, until the latter may be discontinued. Skullcap and Valerian offer a good base for a prescription adjusted to meet individual requirements.

Alternatives. Teas: German Chamomile, Gotu Kola, Hops, Lime flowers, Hyssop, Alfalfa, Passion flower, Valerian, Mistletoe, Oats, Lavender, Vervain, Motherwort. 1 heaped teaspoon to each cup boiling water; infuse 5-15 minutes; half-1 cup thrice daily.

Decoctions: Valerian, Devil’s Claw, Siberian Ginseng, Lady’s Slipper. Jamaica Dogwood, Black Cohosh.

Tablets/capsules. Motherwort, Dogwood, Valerian, Skullcap, Passion flower, Mistletoe, Liquorice. Powders. Formulae. Alternatives. (1) Combine equal parts Valerian, Skullcap, Mistletoe. Or, (2) Combine Valerian 1; Skullcap 2; Asafoetida quarter. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily. Formula No 2 is very effective but offensive to taste and smell.

Practitioner. Tincture Nucis vom. once or twice daily, as advised.

Aloe Vera gel (or juice). Russians tested this plant on rabbits given heavy drug doses and expected to die. Their survival revealed the protective property of this plant: dose, 1 tablespoon morning and evening. Aromatherapy. Sniff Ylang Ylang oil. Lavender oil massage for its relaxing and stress-reducing properties.

Diet. Avoid high blood sugar levels by rejecting alcohol, white flour products, chocolate, sugar, sweets and high cholesterol foods.

Supplements. Daily. Multivitamins, Vitamin B-complex, B6, Vitamin C 2g, Minerals: Magnesium, Manganese, Iron, Zinc. Change of lifestyle. Stop smoking. Yoga.

Notes. “Do not withdraw: insulin, anticoagulants, epileptic drugs, steroids, thyroxin and hormone replacement therapy (the endocrine glands may no longer be active). Long-term tranquillisers e.g., Largactil or any medicament which has been used for a long period. Patients on these drugs are on a finely-tuned medication the balance of which may be easily disturbed.” (Simon Mills, FNIMH)

Counselling and relaxation therapy.

The Committee on Safety of Medicines specifically warns against the abrupt cessation of the Benzodiazepines and similar tranquillisers because of the considerable risk of convulsions. ... drug dependence

Emphysema

In normal breathing the lungs spring back into their usual shape after expansion by the act of breathing-in. In emphysema, elasticity has lost its spring so the lungs become permanently expanded. Differs from chronic bronchitis by destroying walls of the air sacs. The chest is barrel-shaped through hyperinflation. Trumpeter’s lung; glass-blower’s disease, smoker’s disease. Stethoscope reveals ‘distant’ heart sounds of right heart failure, for which Hawthorn is indicated. Breathlessness on exertion. The victim cannot dispel the sensation of puffed-up lungs.

Through a lack of oxygen other muscles weaken. Rate of breathing may increase from 14-30 times per minute. Always ‘clearing the throat’. Overweight worsens.

Alternatives. Lobelia, Wild Thyme, Coltsfoot. Ephedra (practitioner only).

To loosen and thin tough mucus: Iceland Moss, Garlic, Coltsfoot, Gum ammoniac, Fenugreek seeds, Liquorice, Khella.

Decoction. Equal parts: Valerian, Liquorice root. 1-2 teaspoons to each cup boiling water; simmer 15 minutes. Dose: 1 cup once or twice daily and at bedtime.

Tablets/capsules. Lobelia, Iceland Moss, Garlic.

Formula. Equal parts: Elecampane, Iceland Moss, Wild Thyme. Dose: Powders: 750mg (three 00 capsules or half a teaspoon). Liquid extracts: 1-2 teaspoons. Tinctures: 1-3 teaspoons. In water, honey or banana mash, thrice daily, and during the night if necessary.

Practitioner. Alternatives.

Formula (1). Liquid extracts: Ephedra 2; Elecampane 1; Lobelia 1. Dose – 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1-2 teaspoons. Tinctures: 1-3 teaspoons in water etc as above.

Formula (2). Liquid extracts: Ephedra 2; Liquorice 1. Dosage same as Formula 1. The action of both formulae is improved when taken in cup of Fenugreek decoction.

Hyssop Wine. Good responses observed. 1oz herb macerated in 1 pint white wine or Vodka for 3-4 weeks; shake daily.

A. Barker FNIMH. Liquid extract Mouse Ear 60 drops; Liquid extract Pleurisy root 30 drops; Tincture Goldenseal 30 drops; Tincture Myrrh 20 drops; Tincture Ginger 20 drops. Pure bottled or distilled water to 8oz (240ml). Dose: 2 teaspoons every 3 hours.

Diet. Low salt. High fibre. Avoid all dairy products.

Supplements. Daily. Vitamin A 7500iu. Vitamin E 400iu. Folic acid 1mg. Vitamin C 200mg. Iodine, iron. Deep-breathing exercises. 2 Garlic tablets/capsules at night. For acute respiratory infections that irritate emphysema add Echinacea. ... emphysema

Fibrositis

Muscular rheumatism. Painful, sore and aching muscles due to over-exertion, septic foci (bad teeth, grumbling appendix, infected sinuses etc), or an over-growth of fibrous tissue due to inflammatory change in muscles. Also due to injury or faulty food combinations.

Alternatives. Bladderwrack, Bogbean, Cayenne, Dandelion, Black Cohosh (especially after violent exercise), Ginger, Horseradish, Sweet Chestnut, St John’s Wort, Rosemary.

Tea. Celery seed.

Tablets/capsules. Black Cohosh, Celery, White Willow, Devil’s Claw, Ligvites, Wild Yam.

Alternative formulae:– Powders. Formula. White Willow 2; Cramp bark half; Guaiacum quarter; Liquorice quarter. Mix. 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Liquid Extracts. Formula. Rosemary 1; St John’s Wort 1; Black Cohosh half; Valerian half. Mix. Dose: 30-60 drops thrice daily.

Tinctures. Formula. Dandelion 2; Celery 1; Bogbean 1. Fennel half. Dose: 1-2 teaspoons thrice daily. Topical. Aromatherapy. 2 drops each, Origan (Wild Marjoram), Scots Pine, Rosemary, to 2 teaspoons vegetable oil (Almond, etc). Massage. Capsicum liniment.

Poultice. Leaves of Lobelia, Ragwort or Wintergreen.

Analgesic cream. Hot Epsom Salts bath, once weekly.

Diet. Lacto-vegetarian. Oily fish. Dandelion coffee.

Supplements. Daily. Vitamin B6 (50mg), C (500mg), Calcium Pantothenate (500mg), Dolomite. ... fibrositis

Galen

130-200 AD. Greek physician and philosopher. Born in what is now known as Turkey, (129- 199 AD). Prolific writer on medical subjects, gathering recorded knowledge up to his time and confirming it on such a foundation of truth that his works were studied up to the 17th century. He gained such a reputation in Rome that he received, but declined, an offer of the post to Physician to the Emperor. He attended Marcus Aurelius and his son, heir to the throne. He was an accurate observer, especially of muscles and bones, and demonstrated that arteries carry blood and not air.

In his diagnosis he laid great stress on the pulse, which is observed today. He believed in ‘critical days’ when men and women are more accident-prone and gave diminished performance due, he believed, to the moon.

Galenist physicians who followed him did not deviate from his ancient formulae, for better or worse, largely of herbs of the whole plant given in tincture or extract form. Apothecaries and chemists departed from the tradition when they isolated what they believed to be the active principles of the plant – often in a form of extreme concentration and small bulk. ... galen

Gall-stones

Any obstruction to the free flow of bile causes stagnation within the gallbladder. Deposits of bile pigments form (bile sand). Under chemical change, these small masses become encrusted with cholesterol and converted into gall-stones. Common in overweight middle-aged women, “fair, fat and forty”. Fifteen per cent of the world’s population are affected. Pain may be mistaken for heart disorder.

Stones are of two main types: cholesterol and bile pigment. Cholesterol stones are composed of about 70 per cent cholesterol. Bile pigment stones are brittle and hard and brown or black. Stones cause gall duct obstruction, inflammation of the gall bladder and biliary colic.

Biliary colic can be one of the most excruciatingly painful conditions known.

Symptoms: extreme tenderness in upper right abdomen, dyspepsia, flatulence, vomiting, sweating, thirst, constipation. Prolonged obstruction leads to jaundice. Pain should be evaluated by a competent authority: doctor or hospital. Large stones will require surgery.

Alternatives. Combinations should include a remedy for increasing the flow of bile (cholagogue); to disperse wind (carminative); and for painful spasm.

BHP (1983) – Barberry, Greater Celandine, Balmony, Wahoo, Boldo, Chiretta, Dandelion.

Indicated: Cholagogues, Bitters to meet reduced secretion of bile. To prevent infection – Echinacea. Preventative measure for those with tendency to form stone – 2 Blue Flag root tablets/capsules, or half a teaspoon Glauber salts in morning tea, or 420mg Silymarin (Milk Thistle), daily.

Teas. Boldo, Black Horehound, Horsetail, Parsley Piert, Milk Thistle, Strawberry leaves, Wood Betony. Dr Hooper’s case: “An Indian Army officer suffered much from gall-stones and was advised to take Dandelion tea every day. Soon the symptoms left him and he remained free from them for over 20 years.” (John Clarke, MD)

Decoction. 1oz each: Milk Thistle, Centuary, Dandelion root, in 3 pints water. Bring to boil. Simmer down to 2 pints. Strain. One cup 3 times daily an hour before meals.

Tablets/capsules. Cramp bark (acute spasm). Wild Yam (spasmolytic and bile liquifier).

Powders. Equal parts: Cramp bark, Wahoo, Dandelion. Dose: 750mg (three 00 capsules or half a teaspoon) every 2 hours for acute cases.

Study. Silymarin 420mg daily on patients with a history of gall-stones. Results showed reduced biliary cholesterol concentrations and considerably reduced bile saturation index. (Nassuato, G. et al, Journal of Hepatology 1991, 12)

Captain Frank Roberts. Advises Olive oil and Lemon treatment (see below) followed by his prescription: Liquid Extract Fringe Tree 1oz (30ml); Liquid Extract Wahoo 1oz; Liquid Extract Kava- Kava 1oz; Liquid Extract Black root 1oz; Honey 2oz. Dose: teaspoon after meals – minimum 3 meals daily – in wineglass tepid water.

Liquid Extract Barberry: 20-60 drops in water every 2 hours.

Finlay Ellingwood MD. Liquid Extract Fringe Tree bark 10ml; Liquid Extract Greater Celandine 10ml; Tincture Gelsemium 5ml. Dose: 10 drops in water half hourly for acute cases.

Alfred Vogel. Suggests Madder root, Clivers and Knotgrass have solvent properties.

Juices believed to have solvent properties: Celery, Parsley, Beet, Carrot, Radish, Lemon, Watercress, Tomato.

Olive oil and Lemon treatment. Set aside a day for the operation. Take breakfast. No meals for the rest of the day. About 6pm commence by drinking 1 or 2 ounces of the oil. Follow with half-1 cup fresh Lemon juice direct from the fruit in a little warm water. Dilute no more than necessary. Alternate drinks of Olive oil and Lemon juice throughout the evening until one pint or more Olive oil, and juice of 8-9 Lemons been consumed. Drink at intervals of 10 minutes to half an hour. Following 3 days pass stools into a chamber and wash well in search for stones and ‘bile sand’.

Practitioner. For spasm on passing stone: Tincture Belladonna: 20 drops in 100ml water: 1 teaspoon hourly.

Compresses: hot wet. Castor oil packs, or hot water packs over painful area.

Enema. Strong Catmint tea – 2 pints.

Diet. Commence with 3 day juice-fast: no solid food. Turmeric used at table as a condiment. Avoid cheese, sugar. Vegetarian diet. Studies show those who eat meat are twice as likely to develop stone. Less saturated fat and more fibre. Vegetable margarine instead of butter. Dandelion coffee or juices in place of caffeine beverages. High vegetable protein; high carbohydrate; high fibre. Oats. Artichokes, honey, molasses, unrefined cereals. Vegetable oil in cooking.

Supplements. Daily. Vitamin C, 2-3g. Vitamin E, 500iu. Choline 1g.

Note: Subjects with a sensitive skin who enjoyed sunbathing are at a raised risk of having gallstones. (Journal of Epidemiology and Community Health)

Gall-stones may form if weight is lost rapidly when on a low calorie diet. ... gall-stones

Ground Ivy

Glechoma hederacea. Nepeta hederacea L. German: Gundermann. French: Lierre terrestre. Spanish: Hiedra terrestre. Italian: Edera terrestre. Dried herb. Keynote: catarrh.

Constituents: flavonoids, oil, sesquiterpenes, a bitter principle.

Action: Anti-catarrhal, expectorant, diuretic, an important astringent for stomach, intestines and colon. Diaphoretic, anti-scorbutic, tonic, anti-inflammatory.

Uses: Catarrh: chronic bronchial, nasal; catarrhal deafness, tinnitus (buzzing in the ears). Sinusitis. Kidney disease (supportive to primary treatment). Dyspepsia. Piles.

Reported to have been used with success for cancer of the bladder.

Combinations. Combines well with Agrimony (equal parts) for irritable bowel. Combines with Goldenseal 1; (Ground Ivy 4) for cystitis.

Preparations: Average dose: 2-4 grams. Thrice daily.

Tea: 1-2 teaspoons to each cup boiling water; infuse 15 minutes. Half-1 cup.

Home tincture: 1oz dried or fresh herb to 5oz 25 per cent alcohol (Vodka, etc). Macerate 8 days; shake daily. Strain. Dose: 1-2 teaspoons in water.

Liquid Extract: 2-4ml. ... ground ivy

Haemorrhoids

Varicose veins around the anus and low bowel due to poor local circulation. First degree haemorrhoids, remain inside the rectum, but may bleed. Second degree haemorrhoids, bleed and protrude beyond the anus but return after defecation. Third degree haemorrhoids, remain outside the anus and have to be pushed back manually. Blood is bright red.

Causes: constipation, sluggish liver, grumbling appendix, pregnancy, etc. Underlying cause must be treated. Pilewort and Stone root are key remedies.

Alternatives. Teas from any of the following: Butcher’s Broom, Balmony, Bilberry, Beth root, Bistort, Comfrey, Cranesbill, Figwort, Ground Ivy, Horsechestnut, Ladies Mantle, Nettles, Oak bark, Pilewort, Plantain, Silverweed, Stone root, Tormentil, Wild Yam, Witch Hazel, St John’s Wort.

Alternative formulae. Tea. (1) Equal parts, Yarrow, Witch Hazel leaves, German Chamomile. (2) Equal parts, Yarrow, Pilewort, Mullein. (3) Equal parts, Plantain, Figwort, Pilewort. 1-2 teaspoons to each cup boiling water; infuse 15 minutes. Half-1 cup thrice daily before meals.

Tablets/capsules. Pilewort. Cranesbill. Wild Yam. Blue Flag root.

Powders. Formula. Equal parts, Pilewort 1; Figwort 1; Stone root half. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Tinctures. Formula. Butternut 1; Figwort 1; Cascara quarter. One 5ml teaspoon in water thrice daily. Alternative: Combine Hawthorn 2; Stone root 1. Dose: 30-60 drops in water thrice daily.

Enema. Strong infusion of Raspberry leaves: 2oz to 2 pints boiling water. Steep 20 minutes, strain. Improves with addition of 5 drops Tincture Myrrh.

Suppositories. 1 part Liquid Extract Witch Hazel or German Chamomile to 5 parts Cocoa butter. Ointments: Pilewort, Chickweed, Figwort, Aloe Vera, Horse Chestnut, Houseleek.

Psyllium seeds (light) (Ispaghula) increases bulk of the stools making them softer and easier to pass.

To alleviate itching and assist healing: insert into the anus fresh peeled Aloe Vera or Houseleek. Alternatives: make a paste of quarter of a teaspoon of any of the following powders with few drops of milk: Comfrey, Pilewort, Stone root and apply externally, holding in position with a binder.

Vitamin E capsules. Piles that had resisted all other forms of treatment rapidly cleared. Insert one capsule into rectum night and morning.

Diet: Low salt, low fat, high fibre.

Supplements. Vitamins A, B-complex, B6, C, and E. Calcium. Zinc.

Supportives. Sitz bath. Sponge anus with cold water. ... haemorrhoids

Hawthorn

White thorn. Crataegus oxyacanthoides Thuill. Or C. monogyna Jacq. French: Aube?pine. German: Hagedorn. Spanish: Espina blanca. Italian: Marruca bianca. Parts used: Dried flowers, leaves, fruits. Keynote: heart.

Constituents. Flavonoids, phenolic acids, tannins, amines.

Action. Positive heart restorative. Coronary vasodilator BHP (1983), antispasmodic, antihypertensive, adaptogen, diuretic, sedative to nervous system, cholesterol and mineral solvent. Action lacks the toxic effects of digitalis. Useful where digitalis is not tolerated.

Uses: To increase blood flow through the heart. Strengthens heart muscle without increasing the beat or raising blood pressure. Enhances exercise duration. Myocarditis with failing compensation. Improves circulation in coronary arteries. Arteriosclerosis, atheroma, thrombosis, rapid heart beat, paroxysmal tachycardia BHP (1983), fatty degeneration; angina, enlargement of the heart from over-work, over- exercise or mental tension, alcoholic heart, Buerger’s disease, intermittent claudication, risk of infarction, dizziness (long term), mild to moderate hypertension, insomnia. Used by sportsmen to sustain the heart under maximum effort.

Preparations: Thrice daily.

Tea. Leaves and flowers. 1-2 teaspoons to each cup boiling water; infuse 5-10 minutes. Dose: 1 cup. Traditional for insomnia or for the heart under stress.

Decoction. Fruits. 1-2 heaped teaspoons haws to each cup water; simmer gently 2 minutes. Dose: half-1 cup.

Tablets/capsules. Two 200-250mg.

Liquid extract. 8-15 drops in water.

Tincture. 1:5 in 45 per cent alcohol, dose: 15-30 drops (1-2ml).

Popular combinations:–

With Mistletoe and Valerian (equal parts) as a sedative for nervous heart.

With Lily of the Valley 1; Hawthorn berries 2; for cardiac oedema.

With Lime flowers, Mistletoe and Valerian (equal parts) for high blood pressure.

With Horseradish or Cayenne, as a safe circulatory stimulant.

Gradual onset of action. Low incidence of side-effects. No absolute contra-indications.

Note: Dr D. Greene, Ennis, County Clare, Eire, attained an international reputation for treatment of heart disease keeping the remedy a secret. Upon his death his daughter revealed it as a tincture of red-ripe Hawthorn berries. Pharmacy only ... hawthorn

Heart

SIMPLE HEART WEAKNESS. General debility of the heart in the absence of structural defect or serious disorder. A feeble heart may sometimes be well served by nervines alone: Skullcap, Chamomile, Betony, Valerian, especially if accompanied by a sinking feeling.

Alternatives. Tea. Combine equal parts: Motherwort, Valerian, Borage. 1-2 teaspoons to each cup boiling water; infuse 10 minutes. 1 cup once or twice daily.

Decoction. Combine equal parts: Hawthorn berries, Valerian. 1-2 teaspoons to each cup water simmered gently 10 minutes. 1 cup once or twice daily.

Tablets/capsules. Hawthorn, Motherwort, Cayenne, Valerian, Skullcap.

Alternative formulae. Tinctures.

(1) Cactus 15ml; Hawthorn 15ml; Capsicum 1ml. Dose: one teaspoon in water thrice daily.

(2) Hawthorn 15ml; Valerian 15ml; Ginseng 10ml. Dose: one teaspoon in water thrice daily.

(3) Saw Palmetto 20ml; Damiana 10ml; Hawthorn 20ml; Capsicum 1ml. Dose: 1-2 teaspoons in water thrice daily.

Practitioner. Tincture Arnica 1-2 drops in water morning and evening for 7 days.

Diet. Foods rich in Vitamins B, B6, C, E. See also: DIET – HEART AND CIRCULATION. ... heart

Heath And Heather, Ltd.

From small beginnings this unique herbal enterprise grew into a national concern. Founded: 1920 by James Ryder, St Albans, Herts. On his death in 1937 the company passed to Mrs Joan Ryder. Vendors of fine herbal preparations and publishers of a number of booklets including: Gateway to Health and Famous Book of Herbs. Following the company’s ‘take-over’ from Booker Health Foods in 1987, it passed to The London Herb and Spice Co. Ltd., who maintain it as a brand leader in the health food trade.

Herbal combinations include: Rheumatic Pain tablets No 100: formula:– Guaiacum resin BPC ’49 50.0mg; Capsicum oleoresin BPC 0.6mg; the solid extracts of: Rhubarb (alc 60 per cent 1-4) BPC ’54 15mg; Uva Ursi (Aq 4:10) BPC ’34 12.0mg; Bogbean (Aq 1:4) 30.0mg; Celery seed (Aq l:4) BPC ’49 30.0mg.

Indigestion and Flatulence tablets No 80: formula:– Capsicin BPC ’23 0.25mgm; dried aqueous extract of Skullcap (3-10) BPC ’34 3mgm; Valerian BPC 14mgm; Fennel seed BPC 14mgm; Myrrh BPC 19mgm; Papain BPC ’54 1mgm; Peppermint oil BP 0.0006ml. ... heath and heather, ltd.

Horehound, White

 Marrubium vulgare L. German: Maurerandorn. French: Marrube blanc. Spanish: Marrubio. Italian: Marrobio bianco. Dutch: Gemeene malrove. Flowering tops and leaves. Keynote: chest.

Constituents: Marrubiin, volatile oil, tannins, alkaloids, diterpene alcohols.

Action: stimulating expectorant, mild antispasmodic, sedative, amphoteric, vulnerary, diuretic, stomach and liver bitter tonic.

Uses: Chronic bronchitis, whooping cough, hard cough with little phlegm, common cold, loss of voice, snake bite, dog bite. Chronic gall bladder disease, fevers, malaria, hepatitis, “Yellowness of the eyes”. Combinations. Teas. (1) with Coltsfoot and Hyssop (equal parts) for hard cough. (2) with Lobelia and Iceland Moss for chronic chest complaints.

Preparations: Thrice daily.

Tea. 1 teaspoon to each cup boiling water; infuse 15 minutes. Dose: half-1 cup. Liquid extract BHC Vol 1. 1:1, 20 per cent ethanol. Dose: 1-2ml.

Tincture BHC Vol 1. 1:5, 25 per cent ethanol. Dose: 3-6ml.

Horehound ale: wholesome beverage.

Horehound, Hyssop and Honey Mixture.

Traditional English syrup.

Note: Horehound, Horseradish, Coriander, Lettuce and Nettles are the five bitter herbs eaten by the Jews at their Passover feast according to the Old Testament. ... horehound, white

Horsetail

Shave grass. Pewterwort. Nature’s hoover. Equisetum arvense L. German: Ackerschachtelhalm. French: Equisette. Spanish: Belcho. Italian: rasperella. Chinese: We?n-ching. Dried stems. Keynote: genito-urinary system. A natural source of silicic acid, ashes containing 70 per cent silica soluble in water and alcohol.

Constituents: flavonoids, alkaloids, sterols, silicic acid.

Action: haemostatic for bleeding of genitourinary organs, styptic, a soothing non-irritating diuretic. Increases coagulability of the blood. Remineraliser. Anti-atheroma. Antirheumatic. Astringent. Immune enhancer. White blood cell stimulator.

Uses: Blood in the urine, prostatitis, bed-wetting, dropsy, chronic bladder infections, incontinence in the aged, catarrh of the urinary organs, gravel, urethritis of sexual transmission with bleeding, stricture, severe pain in the bladder unrelieved by passing water, constant desire to pass water without relief. Carcinoma of the womb: cure reported. Foetid discharges of STD. Arteriosclerosis.

Silica, as in Horsetail, preserves elasticity of connective tissue; controls absorption of calcium and is a necessary ingredient of nails, hair, teeth and the skeleton. Its cleansing properties rapidly remove urates, uric acid and cellulites from the system. Hastens repair of tissue after lung damage of tuberculosis or other diseases.

Combinations. (1) With Shepherd’s Purse for blood in the urine. (2) With Pulsatilla to inhibit growth of uterine fibroid. (3) With Buchu for cystitis. (4) With Oats and Goldenseal for renal exhaustion. “Combines well with Hydrangea for non-malignant prostatitis.” (F. Fletcher Hyde) Arteriosclerosis. (Dr Max Rombi)

Preparations: Horsetail has a heavy mineral content (silica, selenium and zinc) therefore treatment is best staggered so as to avoid kidney strain – one month, followed by one week’s break. Average dose: 1 to 4 grams; thrice daily.

Tea: half-1 teaspoon to cup water; bring to boil; simmer 5 minutes; infuse 30 minutes. Dose: half-1 cup, cold.

Liquid extract BHC Vol 1. 1:1 in 25 per cent ethanol. Dose: 1-4ml (15-60 drops).

Home tincture: 1 part herb to 5 parts 25 per cent alcohol (gin, Vodka, etc). Steep 14 days, shake daily. Dose: 2-5ml (30-75 drops) in water.

Poultice: “Place double handful herb in a sieve and place over a pot of boiling water (double boiler, etc). The soft hot herbs are placed between a piece of linen and applied to ulcer, adenoma, cyst or tumour.” (Maria Treben)

Bath. 9oz leaves: bring to boil in 1 gallon water. Simmer 5 minutes; strain. Add to bath water.

Enema: 1 pint weak tea for infants with kidney disorders. ... horsetail

Herbal Medicine

“There is a large body of opinion to support the belief that a herb that has, without ill-effects, been used for centuries and capable of producing convincing results, is to be regarded as safe and effective.” (BHMA) Claims for efficacy are based on traditional use and inclusion in herbals and pharmacopoeias over many years. Their prescription may be prefixed by: “For symptomatic relief of . . .” or “An aid in the treatment of . . .”

To establish efficacy of treatment for a named specific disease by herbs, the DHSS requires scientific data presented to the Regulatory authorities for consideration and approval.

A product is not considered a herbal remedy if its active principle(s) have been isolated and concentrated, as in the case of digitalis from the Foxglove. (MAL 2. Guidance notes)

A herbal product is one in which all active ingredients are of herbal origin. Products that contain both herbal and non-vegetable substances are not considered herbal remedies: i.e. Yellow Dock combined with Potassium Iodide.

The British Government supports freedom of the individual to make an informed choice of the type of therapy he or she wishes to use and has affirmed its policy not to restrict the general availability of herbal remedies. Provided products are safe and are not promoted by exaggerated claims, the future of herbal products is not at risk. A doctor with knowledge and experience of herbal medicine may prescribe them if he considers that they are a necessary part of treatment for his patient.

Herbalism is aimed at gently activating the body’s defence mechanisms so as to enable it to heal itself. There is a strong emphasis on preventative treatment. In the main, herbal remedies are used to relieve symptoms of self-limiting conditions. They are usually regarded as safe, effective, well-tolerated and with no toxicity from normal use. Some herbal medicines are not advised for children under 12 years except as advised by a manufacturer on a label or under the supervision of a qualified practitioner.

World Health Organisation Guidelines

The assessment of Herbal Medicines are regarded as:–

Finished, labelled medicinal products that contain as active ingredients aerial or underground parts of plants, or other plant material, or combinations thereof, whether in the crude state or as plant preparations. Plant material includes juices, gums, fatty oils, essential oils, and any other substances of this nature. Herbal medicines may contain excipients in addition to the active ingredients. Medicines containing plant material combined with chemically defined active substances, including chemically defined, isolated constituents of plants, are not considered to be herbal medicines.

Exceptionally, in some countries herbal medicines may also contain, by tradition, natural organic or inorganic active ingredients which are not of plant origin.

The past decade has seen a significant increase in the use of herbal medicines. As a result of WHO’s promotion of traditional medicine, countries have been seeking the assistance of WHO in identifying safe and effective herbal medicines for use in national health care systems. In 1989, one of the many resolutions adopted by the World Health Assembly in support of national traditional medicine programmes drew attention to herbal medicines as being of great importance to the health of individuals and communities (WHA 42.43). There was also an earlier resolution (WHA 22.54) on pharmaceutical production in developing countries; this called on the Director-General to provide assistance to the health authorities of Member States to ensure that the drugs used are those most appropriate to local circumstances, that they are rationally used, and that the requirements for their use are assessed as accurately as possible. Moreover, the Declaration of Alma-Ata in 1978 provided for inter alia, the accommodation of proven traditional remedies in national drug policies and regulatory measures. In developed countries, the resurgence of interest in herbal medicines has been due to the preference of many consumers for products of natural origin. In addition, manufactured herbal medicines from their countries of origin often follow in the wake of migrants from countries where traditional medicines play an important role.

In both developed and developing countries, consumers and health care providers need to be supplied with up-to-date and authoritative information on the beneficial properties, and possible harmful effects, of all herbal medicines.

The Fourth International Conference of Drug Regulatory Authorities, held in Tokyo in 1986, organised a workshop on the regulation of herbal medicines moving in international commerce. Another workshop on the same subject was held as part of the Fifth International Conference of Drug Regulatory Authorities, held in Paris in 1989. Both workshops confined their considerations to the commercial exploitation of traditional medicines through over-the-counter labelled products. The Paris meeting concluded that the World Health Organisation should consider preparing model guidelines containing basic elements of legislation designed to assist those countries who might wish to develop appropriate legislation and registration.

The objective of these guidelines, therefore, is to define basic criteria for the evaluation of quality, safety, and efficacy of herbal medicines and thereby to assist national regulatory authorities, scientific organisations, and manufacturers to undertake an assessment of the documentation/submission/dossiers in respect of such products. As a general rule in this assessment, traditional experience means that long-term use as well as the medical, historical and ethnological background of those products shall be taken into account. Depending on the history of the country the definition of long-term use may vary but would be at least several decades. Therefore the assessment shall take into account a description in the medical/pharmaceutical literature or similar sources, or a documentation of knowledge on the application of a herbal medicine without a clearly defined time limitation. Marketing authorisations for similar products should be taken into account. (Report of Consultation; draft Guidelines for the Assessment of Herbal Medicines. World Health Organisation (WHO) Munich, Germany, June 1991) ... herbal medicine

Hoxsey

Harry M. M.D. Cancer specialist. Great Grandson of John Hoxsey, American physician, who in 1840 observed one of his horses with cancer cure itself by foraging for certain herbs. Noticing the herbs (Alfalfa, Red Clover, etc) he gathered them and fed them to other animals with the disease with conspicuous success.

The Hoxsey Cancer Clinic was founded in Dallas, which became a mecca for the herbal treatment of that disease. However, he received such persecution from the American Medical Association that he was persuaded to sign a contract transferring to them his herbal formulae, medicines and ointments, and to abandon his practice. This he did in good faith but the opposition continued. Worn out by long prison sentences for practising medicine without a licence, he died a broken man.

Though it is still illegal to offer the Hoxsey treatment in the United States, his main formula is still used by individuals left to their own resources.

Formula. Liquid Medicine: Red Clover, Burdock root, Queen’s Delight root, Barberry root, Liquorice, Poke root, Cascara sagrada, Potassium iodide, Prickly Ash bark, Buckthorn powder.

Pills: Red Clover, Queen’s Delight root, Poke root, Buckthorn, Pepsin.

A popular version revised by Paul Bergner, American Medical Herbalist reads: Liquorice 4 parts; Red

Clover 4 parts; Burdock 2 parts; Queen’s Delight 2 parts; Mountain Grape 2 parts; Poke root 2 parts; Prickly Ash bark 1 part; Frangula bark 1 part. (P. Bergner, ‘Botanic Medicine: Alterative Medicine’. Townsend Letter for Doctors, Nov. 1988, No 64, p487-8) ... hoxsey

Hyssop

Hyssopus officinalis L. German: Ysop. French: Hyssope officinale. Spanish: Hisopo. Iranian: Ush-naz-daoud. Indian: Jupha?. Arabian: Zupho. Herb. Keynote: lungs.

Constituents: volatile oil, flavonoids, terpenoids, Mucilage, Resin.

Action: to induce heavy sweating in fevers, hypertensive to increase blood pressure, expectorant, emmenagogue, mild analgesic, diuretic. Antispasmodic. (Mills) External antiseptic.

Antiviral action against herpes simplex virus reported. (E.C. Herrmann, Jr., & L.S. Kucera, Proc. Soc. Exp. Biol. Med., 124, 874, 1967)

Uses: Bronchitis, colds, chills, catarrh, sore throat. Has been used in hysteria, anxiety states and petil mal BHP (1983). Respiratory disorders of nervous background in children.

Externally: eczema, bruises.

Combinations: with Betony (tea: equal parts) for tendency to epileptic episodes.

Preparations: Average dose: 2-4 grams. Thrice daily.

Tea: 1 heaped teaspoon to each cup boiling water: infuse 15 minutes. Half-1 cup freely in acute conditions; childrens’ fevers.

Liquid Extract: 30-60 drops, in water.

Tincture BHP (1983) 1:5 in 45 per cent alcohol; dose 2-4ml.

Essential oil. 1-2 drops in water or honey after meals (digestive). 5-6 drops in 2 teaspoons Almond oil (chest rub for congested bronchi). 1-2 drops in honey between meals for worms in children. ... hyssop

Iceland Moss

Cetraria islandica, L. German: Torfmoos. French: Sphaigne. Spanish: Hiusgo. Italian: Stagno. Indian: Lahana. Dried lichen. Keynote: cough.

Constituents: cetrarin, lichen acids, terpenes, lichenin.

Action: demulcent, expectorant, antitussive, nutrient, antemetic. Helps arrest permanent respiratory damage in wasting diseases. Highly active in chest infections. Bitter tonic. Mucilage.

Uses: Loss of weight in terminal or wasting diseases with exhaustion and vomiting. To improve digestion. Vomiting – to arrest. Catarrh of nose, throat and chest. To break-up tough mucus in respiratory organs. Chronic bronchitis, cough. Blocked sinuses.

Combinations: with Goldenseal for wasting diseases: with Lobelia for chronic respiratory disorders. Preparations. Average dose: 1-2 grams. Thrice daily.

Decoction. 1 teaspoon to each cup water, gently simmer 20 minutes. Dose: half-1 cup.

Tincture BHP (1983). 1 part to 5 parts 40 per cent alcohol. Dose: 1-1.5ml.

Tablets/capsules. Popular formula: Iceland Moss BHP (1983) 250mg; Liquorice BP 30mg; Lobelia BP 20mg. ... iceland moss

Ipecacuanha Root

Cephaelis ipecacuanha (Brot.) A. Rich. German: Brachwurzel. French: Ipecacuanha. Spanish: Ipecacuanha. Italian: Ipecaquana. Rhizome and root. Practitioner use only. Contains alkaloid and saponin emetine, glycosides, tannins.

Action: expectorant, diaphoretic, antiprotozal BHP (1983), emetic (large doses). Acts upon the pneumogastric nerve. Antispasmodic. Stimulant to mucous membranes.

Uses: to liquefy bronchial phlegm and promote expectoration. Sore throat, whooping cough, stubborn cough. Amoebic dysentery. Expulsion of mucus from the chest. Alternative to a stomach pump to induce vomiting.

Combinations: with Lobelia for respiratory disorders. With Tincture Myrrh for bowel infection, orally or by enema.

Preparations: Average dose, rhizome and roots: 25-100mg. Thrice daily. Dose more accurately controlled by use of liquid extract or tincture rather than infusion or decoction.

Liquid extract BP 1973: dose 0.025 to 0.1ml. Emetic dose – 0.5 to 2ml.

Tincture BP (1973). Dose 0.25 to 1ml. Emetic dose 5 to 20ml.

Cough mixtures: an ingredient of. (Potter’s Balm of Gilead) etc. Contra-indications: shock, heart disease. ... ipecacuanha root

Kava Kava

Ava Pepper. Piper methysticum, Forster. German: Kawa pfeffer. French: Kawa. Spanish: Kava kava. Italian: Pepe kava. Parts used: rhizome and root.

Constituents: Pipermethysticine (alkaloid), Pyrone derivative.

Action: antimicrobial with special reference to STDs with mucopurulent discharge, including gonorrhoea. Also effective against Bacillus Coli. Antiseptic stimulant, mild analgesic for painful spasm, antispasmodic, nerve relaxant, diuretic, stimulant, tonic.

Uses: Genito-urinary infections, orchitis, vaginitis, urethritis, Candida, violent itching, ichthyosis, metritis, inflammation of the Fallopian tubes, incontinence in the aged with bladder weakness, infection of kidney, bladder and prostate gland, conditions arising from excess of uric acid, joint pains of rheumatism following STD infection, bed-wetting. A powerful soporific for chronic insomnia, ensuring dreamless sleep with no known ill-effects on rising.

Combinations: with Sarsaparilla for STDs. With Black Cohosh for rheumatism following STDs. Preparations. Average dose: 2-4g. Thrice daily.

Decoction. 1oz to 1 pint (30g to 500ml) water, simmer in gentle heat down to three-quarters volume. Dose: half-1 cup.

Liquid Extract. Half-1 teaspoon in water.

Powder: 2-4g.

Lotion. 1oz powdered root to 8oz glycerine, macerate 8 days, shake daily. External: for pruritus and most forms of intolerable itching. Add 10 drops Oil Eucalyptus for chronic cases. ... kava kava

Lady’s Mantle

Lion’s foot. Alchemilla vulgaris L. Dried herb (oral), root (topical). Keynote: bleeding.

Constituents: tannins.

Action: powerful styptic and astringent because of its high tannin content. Haemostatic. Alterative. Drying and binding. Menstrual regulator.

Uses: Excessive menstruation. Non-menstrual bleeding of the womb between periods. Children’s summer diarrhoea, colitis with bleeding. Gastric and duodenal ulcer. Children’s convulsions. (Swedish traditional)

Not used in pregnancy.

Combinations. (1) with Avens for gastritis and mucous colitis. (2) with Agnus Castus for menstrual disorders.

Preparations: Average dose: 2-4g. Thrice daily. Tea: 1-2 teaspoons to each cup boiling water; infuse 15 minutes. One cup.

Liquid extract BHP (1983) 1:1 in 25 per cent alcohol. Dose: 2-4ml.

Powdered root. Dose, 2-4g.

Vaginal douche: 2oz to 2 pints (60g to 1 litre) boiling water. Infuse 30 minutes. Inject warm for leucorrhoea, Candida, inflammation; or as a lotion for pruritus.

Decoction (roots) offer a powerful deterrant to passive bleeding. ... lady’s mantle

Lady’s Slipper

Nerve root. American Valerian. Cypripedium pubescens, Willd. German: Frauenschuh. French: Sabot de Ve?nus. Spanish: Zucco. Italian: Calceolo. Dried root and rhizome. Time- honoured North American Indian remedy. Keynote: central nervous system.

Constituents: tannin, resin.

Action: nerve relaxant, autonomic regulator, mild pain-killer, thymoleptic. A fine brain and spinal remedy and should be at the hand of every spinal manipulator. Antidote to caffeine poisoning.

Use s. Nervous excitability, insomnia, irritability, neuralgia, muscle twitching, anxiety states, schizophrenia, pressive headache, nerve tension, epilepsy, pre-menstrual tension, spermatorrhoea, post- influenzal depression, weepiness.

“Yellow Lady’s Slipper was held in big esteem by the Indians as a sedative and an antispasmodic, acting like Valerian in alleviating nervous symptoms . . . said to have proved itself in hysteria and chorea.” (Virgil Vogel)

Combinations. (1) with Oats and Skullcap for anxiety states and (2) with Hops for insomnia with depression BHP (1983).

Preparations: Average dose: 2-4g. Thrice daily.

Tea. Half-1 teaspoon to each cupful water; bring to boil; simmer 2-3 minutes in covered vessel; infuse 15 minutes. Half-1 cup.

Liquid Extract BHP (1983) 1:1 in 45 per cent alcohol. Dose: 2-4ml.

Powder. Dose, 2-4g. ... lady’s slipper

Life Root

Squaw weed. Senecio aureus L. Dried herb. Keynote: menopause.

Constituents: sesquiterpenes, pyrrolizidine alkaloids.

Action: Tonic for relaxed womb, emmenagogue, astringent, mild expectorant.

Uses: Hot flushes of the menopause with nervous instability. Absent, painful or profuse menstruation. Ovarian pain. Stone, gravel. Diarrhoea. Bleeding from mucous surfaces. Prostatitis.

Combinations: with Motherwort for suppressed menses. With Oats for menopause. Preparations. Average dose: 1-4 grams. Thrice daily.

Tea: half-2 teaspoons to cup boiling water; infuse 15 minutes. Dose: half-1 cup. Liquid Extract. Half-1 teaspoon, in water.

Powder: 1-4 grams.

Not now used internally. ... life root

Liquorice Root

The universal herb. Sweet root. Glycyrrhiza glabra L. Shredded or powdered dried root. Long history for strength and long life in Chinese medicine. Sweet of the Pharoahs of Ancient Egypt. Carried by armies of Alexander to allay thirst and as a medicine.

Constituents: volatile oil, coumarins, chalcones, triterpenes, flavonoids.

Action: demulcent expectorant, glycogenconservor, anti-inflammatory, mild laxative. Adrenal restorative (has glycosides remarkably similar to body steroids). ACTH-like activity on adrenal cortex (Simon Mills). Female hormone properties (Science Digest). Regulates salt and water metabolism (Medicina, Moscow, 1965). Anti-stress. Anti-ulcer. Antiviral. Increases gastric juices up to 25 per cent, without altering pH. Aldosterone-like effect. Liver protective. Anti-depressive.

Use s. Adrenal insufficiency – sodium-retention properties suitable for Addison’s disease. Hypoglycaemia. Peptic ulcer – reduces gastric juice secretion. Inflamed stomach. Mouth ulcer. Duodenal ulcer. Respiratory infections: dry cough, hoarseness, bronchitis, lung troubles, catarrh. Tuberculosis (Chinese traditional). In the absence of more effective remedies of value in food poisoning. To prevent urinary tract infections.

Combinations: with Iceland Moss for wasting and cachexia to nourish and increase weight; with Lobelia for asthma and bronchitis: with Raspberry leaves for the menopause; with Comfrey for dental caries.

“Liquorice is recorded as a cancer remedy in many countries.” (J.L. Hartwell, Lloydia, 33, 97. 1970) Preparations. Average dose: 1-5 grams. Thrice daily before meals.

Decoction: half-1 teaspoon to each cup water, simmer 15 minutes. Half-1 cup.

Liquid Extract: 1:1. Dose: 2-5ml.

Sticks: for chewing.

Powdered root: 750mg (three 00 capsules or half a teaspoon).

Diet: Pontefract cakes – use in kitchen for adrenal failure; because of their sodium-retaining properties may be taken as sweets without added sugar. Low salt when taken.

Contra-indicated: In pregnancy, cirrhosis (liver) and in the presence of digitalis.

Note: If over-consumed may result in low potassium levels, high blood pressure and falls in renin and aldosterone. Where taken for a long period, increase intake of potassium-rich foods. May cause fluid retention of face and ankles which could be tolerated while primary disorder is being healed. ... liquorice root

Lovage

Levisticum officinalis, Koch. German: Agyptischer Ku?mmel. French: Ammi. Italian: Sisone. Arabian: Amus. Indian: Ajwain. Malayan: Homama Azamoda. Iranian: Zhinyan. Parts used: root, rhizome.

Constituents: coumarins, butyric acid, volatile oil.

Action: antibiotic (mild), diaphoretic, expectorant, anti-catarrhal, emmenagogue, carminative, diuretic (mild), sedative, antispasmodic.

Uses: flatulent dyspepsia, anorexia, rheumatism, gout, absent or painful menses, mild feverishness in children, renal dropsy (mild), cystitis.

Locally: as a gargle for tonsillitis; mouth wash for mouth ulcers BHP (1983).

Combinations. With Agrimony for indigestion. With Buchu for renal dropsy. With Raspberry leaves for menstrual disorders. Usually combined with other diuretics.

Preparations: Average dose: half-2g. Thrice daily.

Decoction. Half-1 teaspoon to each cup water gently simmered 15 minutes. Dose: one-third-1 cup.

Liquid Extract: 5-30 drops in water.

Oil used in aromatherapy and perfumes.

LOZENGE. A compressed tablet for sucking in the mouth for inflammatory conditions of throat, mouth and chest. Usually has a base of sugar, a demulcent (Comfrey, Marshmallow root, Slippery Elm, Tolu, or Balm of Gilead), together with a binder, such as gum acacia or gum tragacanth. Recipe for simple lozenge: half an ounce (15g) powdered herb; half an ounce sugar; powdered gum 1 teaspoon (3g). Pure spring water – a sufficiency. Mix into a paste, thin-out the mass and press out lozenges with small gauge mould and dry. ... lovage

Lungwort

Pulmonaria officinalis L. Lobaria pulmonaria L. Lichen. Leaves bear a resemblance to the human lung – see: DOCTRINE OF SIGNATURES. So-named because of its traditional use for tuberculosis. Keynote: upper respiratory organs.

Constituents: palmitic acid, linoleic acid, tannins, ergosterol, saponin.

Action: expectorant, demulcent astringent, haemostatic, orexigenic, antibiotic (mild).

Uses: asthma, laryngitis, sore throat, children’s dry cough, whooping cough, haemoptysis, nasal catarrh, bronchitis.

External: open wounds – to avoid infection.

Combinations. With Coltsfoot and White Horehound for TB cough. With Ephedra for difficult breathing. Preparations. Average dose: 2-4g. Thrice daily. Tea: 1 teaspoon to each cup boiling water; infuse 15 minutes; dose: one-third-1 cup. Or may be boiled in milk.

Liquid Extract BHP (1983): 1:1 in 25 per cent alcohol. Dose: 2-4ml.

Balm of Gilead Cough Mixture. ... lungwort

Marshmallow

Schloss tea. Guimauve tea. Althaea officinalis L. German: Malve. French: Guimauve. Spanish: Malvavisco. Italian: Malvavisce. Iranian and Indian: Gul-Khairu. Chinese: K’uei. Dried peeled root.

Keynote: anti-mortification.

Constituents: mucilage, flavonoids, tannins, scopoletin.

Action. Soothing demulcent, emollient, nutrient, alterative, antilithic, antitussive, vulnerary, diuretic. Old European remedy of over 2,000 years.

Uses: Inflammation of the alimentary canal, kidneys, bladder. Ulceration of stomach and duodenum, hiatus hernia, catarrh of respiratory organs and stomach, dry cough, open wounds – to cleanse and heal, cystitis, diarrhoea, septic conditions of moderate severity. Plant supplies an abundance of mucilage for protection of mucous membranes of the mouth, nose and urinary tract in the presence of stone. A poultice or ointment is applied topically to boils, abscesses, ulcers and old wounds to draw effete matter to the surface before expulsion from the body.

Combinations. With Comfrey and Cranesbill (American) for peptic ulceration. With White Horehound, Liquorice and Coltsfoot for pulmonary disease.

Preparations: Average dose, 2-5 grams dried root. Thrice daily. For best results plant should not be boiled.

Cold decoction. Half-1 teaspoon shredded root or powder to each cup cold water; stand overnight. Dose, half-1 cup. Also used externally as a douche for inflamed eyes.

Liquid Extract BHP (1983). 1:1 in 25 per cent alcohol. Dose, 2-5ml.

Tincture. 1 part root to 5 parts alcohol (25 per cent). Dose: 5-15ml.

Traditional ‘Drawing’ ointment: Marshmallow and Slippery Elm.

Ointment (home): 5 per cent powdered root in an ointment base. See: OINTMENTS.

Poultice. Bring powdered root to the boil in milk; add a little Slippery Elm, apply. ... marshmallow

Mistletoe

Viscum album L. German: Mistel. French: Gui blanc. Spanish: Liga. Russian: Olma. Indian: Banda. Italian: Visco quercino. Arabian: Kishmish-j-kawaliyan. Chinese: San-shang-chi-she?ng. Leaves and terminal twigs. Practitioner use only.

Constituents: alkaloids, glycoproteins, polypeptides, flavonoids.

Action: tranquilliser, vasodilator – reducing blood pressure after an initial rise. Cardiac depressant. Used as an alternative to beta-blocking drugs when they produce sore eyes and skin rash. Stimulates the vagus nerve which slows the pulse. Contains acetylcholine. Diuretic. Immune enhancer. Anti-inflammatory. Uses. Arterial hypertension, insomnia, temporal arteritis, nervous excitability, hyperactivity, limb- twitching, epilepsy, (petit mal), chorea, tinnitus, rabies (Dr Laville). Benzodiazepine addiction – to assist withdrawal. Arteriosclerosis (with Horsetail). Headache, dizziness, fatigue.

Cancer: some success reported in isolated cases. Juice of the berries has been applied to external cancers since the time of the Druids. Present-day pharmacy: Iscador (Weleda), Viscotoxin. Pliny the Elder (AD 23-79) and Hippocrates record its use in epilepsy and for tumours. The berries may be prescribed by a medical practitioner only (UK). As an immune enhancer it is used as an adjunct to surgery and radiotherapy for patients for whom cytotoxic drugs are inappropriate because of adverse side-effects. Lymphocytes divide more readily by production of interferon.

Combinations: (1) with Skullcap and Valerian for nervous disorders (2) with Motherwort and Hawthorn for myocarditis (3) with Blue Cohosh for menstrual irregularity (4) with Hawthorn and Lime flowers for benign hypertension. Never combine with Gotu Kola. (Dr John Heinerman)

Preparations: Average dose: 2-6g, or equivalent. Thrice daily.

Tea: 1 heaped teaspoon to each cup cold water steeped 2 hours. Dose: half-1 cup.

Green Tincture. 4oz bruised freshly-gathered leaves in spring to 1 pint 45 per cent alcohol (Vodka, strong wine, etc). Macerate 8 days, shaking daily. Filter and bottle. Dose: 3-5 drops: (every 2 hours if an epileptic attack is suspected).

Powder, capsules: 300mg. 2 capsules thrice daily before meals. (Arkocaps)

Plenosol. (Madaus)

Liquid Extract (1:1): 8-10 drops.

Sale: pharmacy only. ... mistletoe

Motherwort

Leonurus cardiaca L. German: Herzgespann. French: Agripaume. Spanish: Agripalma. Italian: Cardiaca. Chinese: T’ui. Part used: herb.

Constituents: flavonoids, iridoids including rutin, diterpenes.

Action: antispasmodic, laxative, diaphoretic, emmenagogue, vaso-constrictor. (Simon Mills) Nerve and heart sedative. Hypotensive. Action similar to Valerian. (Dr Rudolf F. Weiss) Cardiotonic.

Uses: angina on effort, simple uncomplicated heart conditions to enhance exercise duration; tachycardia from hyperactive thyroid, hypertension, absent or painful menstruation (hence its name), menopausal flushes, schizophrenic tendency, pre-menstrual tension.

“Drink Motherwort tea and live to be a source of continuous astonishment and frustration to waiting heirs.” (Old saying)

Not given in pregnancy.

Combines well with Vervain (equal parts) for relaxing nervine.

Practitioner combinations: Menstrual disorders, equal parts: Black Cohosh, Cramp bark, Motherwort. Heart disorders: Motherwort 1; Hawthorn 1; Lily of the Valley half.

Benzodiazepine addiction to assist withdrawal: equal parts, Motherwort, Skullcap and Valerian. Infusions, extracts or tinctures.

Preparations: Thrice daily.

Tea: 1-2 teaspoons to each cup boiling water; infuse 15 minutes. Half-1 cup.

Tea combination: equal parts, Motherwort, Balm and Lime flowers. 2 teaspoons to cup boiling water: infuse 15 minutes, 1 cup thrice daily. Angina and heart symptoms – to ameliorate.

Liquid Extract: 1:1, 25 per cent alcohol. Dose: 2-4ml (30-60 drops).

Tincture: 1:5, 25 per cent alcohol. Dose: 5-10ml (1-2 teaspoons).

Powders. 2 to 4g.

Tablets/capsules. Popular combination. Powdered extract Motherwort 4:1 – 50mg. Powdered Passion flower BHP (1983) – 90mg. Powdered extract Lime flowers 3:1 – 67mg. For a calming and sedating effect in stressful situations and insomnia. (Gerard House)

Note: Motherwort needs to be taken for weeks. ... motherwort

Ointment Bases

Ointments are semi-solid preparations of a plant remedy in a non-aqueous base to protect, nourish or convey medication to the skin. They are made from a base. A herbal powder or fine- cut material is usually added to the base which will vary according to the substance used. Vaseline is popular as a base, yet many combinations are serviceable from which the following are a small selection. Ointments should not be made in plastic or aluminium vessels.

Perhaps the simplest base is lard or butter, as used by Maria Treben. 2 handfuls (4oz or 120g) finely chopped herbs are digested in 500g lard or butter. Heat gently one hour. Stand overnight. Should be sufficiently fluid next morning to filter through muslin or a wire-mesh strainer. Pour into jars. Very effective but its life is not more than a few weeks.

((a) Vaseline base. Dissolve vaseline. Place 1oz (handful) fresh herb (say . . . Chickweed) or tablespoon dried herb (or 2 teaspoons powder) in 7oz (100g) vaseline melted in low heat. Simmer gently 15 minutes, stirring all the time. Strain through a wire-mesh strainer while hot and pour into air-tight containers.

(b) Vaseline base. To incorporate essential oils; i.e. Oil of Eucalyptus 2ml; Oil of Pine 1ml; Oil of Peppermint 2ml; vaseline to 30 gram. Melt the vaseline. Add oils. Stir until cold. Makes a useful inhalant ointment applied directly to the frontal sinus areas, or inhaled from boiling water. (Fred Fletcher Hyde) (c) Mixed base, suitable for holding liquid extracts, tinctures. Ingredients: parts, Almond oil 12; Liquid Extract (say . . . Comfrey) 5; powdered gum Acacia 3; water (preferably distilled) to 100.

Method: Rub together a small equal amount of well-sieved Acacia powder and water to form a paste – best performed in a pestle and mortar. Add the Almond oil. Mix. Add liquid extract, tincture or oil slowly until a good consistency is reached. Slowly add remaining water and stir. Store in airtight glass jars.

(d) Olive and Beeswax base. Ingredients: 2oz beeswax; 16oz Olive oil.

Method: cut beeswax into slices and dissolve in the Olive oil on a low heat. Stir until all beeswax is dissolved. Place in a stone jar or pyrex vessel 12oz aerial parts of fresh herb material (Marigold, Plantain, Chickweed etc) or 4oz hard woody parts, roots or barks (Comfrey, Marshmallow, etc). Pour on the Olive oil and beeswax. Place in a warm oven for 3 hours; give an occasional stir. While still hot, strain through a wire-mesh strainer into pots. Store in a refrigerator. Where powders are used, the proportion is 2oz for every 16oz Olive oil.

((e) Coconut oil base. Dissolve 7 parts Coconut oil. Add 5 parts powdered herbs and 6 parts beeswax. Simmer gently 1 and a half hours. Strain through warm wire mesh strainer or muslin. Filter if necessary. Pour into jars.

(f) Pile ointment. Prepare, vaseline base. Add, Liquid Extract Pilewort 5 per cent, Liquid Extract Witch Hazel 5 per cent; Tincture Benzoin 5 per cent; Menthol 2 and a half per cent.

((g) Pain Reliever. Prepare, vaseline base. Add Menthol 2 per cent; Eucalyptus 2 per cent; Camphor 2 per cent; Oil of Mustard 0.2 per cent.

(h) Russian traditional. It is still common in country practice to simmer popular herbs (Marigold, Arnica, St John’s Wort) in butter, as above.

Preservatives. Length of life of above ointments is increased by addition of Benzoic acid, Nipagen, etc. Benzoinated lard was once a popular base used in pharmacy. Ointments containing volatile oils should be kept in porcelain or glass pots in preference to synthetic containers. All ointments should be stored out of the light and in a cool place.

Marshmallow and Slippery Elm ointment has a long traditional reputation as a general purposes ointment. ... ointment bases

Analgesic Drugs

Drugs used to relieve pain. The 2 main types are nonopioid and opioid. Nonopioid analgesics, which include aspirin, paracetamol, and nonsteroidal anti-inflammatory drugs (NSAIDs), are useful in the treatment of mild to moderate pain (for example, headache or toothache). Combinationsof a weak opioid analgesic, such as codeine, with a nonopioid analgesic relieve more severe pain. Potent opioids such as morphine are used only when other preparations would be ineffective because they can produce tolerance and drug dependence.

Adverse effects are uncommon with paracetamol. Aspirin and NSAIDs may irritate the stomach lining and cause nausea, abdominal pain, and, rarely, a peptic ulcer. Nausea, drowsiness, constipation, and breathing difficulties may occur with opioid analgesics.... analgesic drugs

Cancer

A group of diseases characterized by the abnormal and unrestrained growth of cells in body organs or tissues. Tumour-forming cells develop when the oncogenes (genes controlling cell growth and multiplication) in a cell or cells undergo a series of changes. A small group of abnormal cells develop that divide more rapidly than normal, lack differentiation (they no longer perform their specialized task), and may escape the normal control of hormones and nerves. Cancers differ from benign neoplasms (abnormal growths, such as warts) in that they spread and infiltrate surrounding tissue and may cause blockages, destroy nerves, and erode bone. Cancer cells may also spread via the blood vessels and lymphatic system to form secondary tumours (see metastasis).

Causes of cancer include environmental factors such as sunlight, smoking, pollutants, alcohol consumption, and dietary factors. These factors may provoke critical changes in body cells in susceptible people. Susceptibility to certain cancers may be inherited.

Many cancers are now curable, usually by combinations of surgery, radiotherapy, and anticancer drugs. For information on particular cancers, refer to the organ in question (for example lung cancer; stomach cancer).... cancer

Fats And Oils

Nutrients that provide the body with its most concentrated form of energy. Fats, which are also called lipids, are compounds containing chains of carbon and hydrogen with very little oxygen. Chemically, fats consist mostly of fatty acids combined with glycerol. They are divided into 2 main groups, saturated and unsaturated, depending on the proportion of hydrogen atoms. If the fatty acids contain the maximum possible quantity of hydrogen, the fats are saturated. If some sites on the carbon chain are unoccupied by hydrogen, they are unsaturated; when many sites are vacant, they are polyunsaturated. Monounsaturated fats are unsaturated fats with only one site that could take an extra hydrogen. Animal fats, such as those in meat and dairy products, are largely saturated, whereas vegetable fats tend to be unsaturated.

Fats are usually solid at room temperature; oils are liquid. The amount and types of fat in the diet have important implications for health. A diet containing a large amount of fat, particularly saturated fat, is linked to an increased risk of atherosclerosis and subsequent heart disease and stroke.

Some dietary fats, mainly triglycerides (combinations of glycerol and 3 fatty acids), are sources of the fat-soluble vitamins A, D, E, and K and of essential fatty acids. Triglycerides are the main form of fat stored in the body. These stores act as an energy reserve and also provide insulation and a protective layer for delicate organs. Phospholipids are structural fats found in cell membranes. Sterols, such as cholesterol, are found in animal and plant tissues; they have a variety of functions, often being converted into hormones or vitamins.

Dietary fats are first emulsified by bile salts before being broken down by lipase, a pancreatic enzyme. They are absorbed via the lymphatic system before entering the bloodstream.Lipids are carried in the blood bound to protein; in this state they are known as lipoproteins. There are 4 classes of lipoprotein: very low-density lipoproteins (VLDLs), low-density lipoproteins (LDLs), high-density lipoproteins (HDLs), and chylomicrons. LDLs and VLDLs contain large amounts of cholesterol, which they carry through the bloodstream and deposit in tissues. HDLs pick up cholesterol and carry it back to the liver for processing and excretion. High levels of LDLs are associated with atherosclerosis, whereas HDLs have a protective effect. (See also nutrition.)... fats and oils

Aids

(acquired immune deficiency syndrome) a syndrome first identified in Los Angeles in 1981; a description of the causative virus – the human immunodeficiency virus (*HIV) – was available in 1983. The virus destroys a subgroup of lymphocytes, the *helper T cells (or *CD4 lymphocytes), resulting in suppression of the body’s immune response (see immunity). Acute (primary) infection following exposure to the virus results in the production of antibodies (seroconversion); their presence, detected by standard tests, indicates that infection has taken place. Primary infection may be accompanied by mild or severe symptoms, lasting an average of 14 days, including fever, fatigue, lymphadenopathy, headache, and rash. Chronic HIV infection, which follows primary infection, lasts an average of 10 years, during which the person may be asymptomatic; it is followed by the development of AIDS. AIDS can be defined by a CD4 level less than 200 cells/? or by the presence of an AIDS-defining illness, such as *Kaposi’s sarcoma, recurrent pneumonia (especially caused by *Pneumocystis jiroveci), any of various lymphomas, or any of certain cytomegalovirus-related diseases.

AIDS is largely a sexually transmitted disease, either homosexually or heterosexually. The two other main routes of spread are via infected blood or blood products (as by drug users sharing contaminated needles) and by the maternofetal route. The virus may be transmitted from an infected mother to the child in the uterus or it may be acquired from maternal blood during parturition; it may also be transmitted in breast milk. HIV has been isolated from semen, cervical secretions, plasma, cerebrospinal fluid, tears, saliva, urine, and breast milk but the concentration shows wide variations. Moreover HIV is a fragile virus and does not survive well outside the body. It is therefore considered that ordinary social contact with HIV-positive subjects involves no risk of infection. However, high standards of clinical practice are required by all health workers in order to avoid inadvertent infection via blood, blood products, or body fluids from HIV-positive people. Staff who become HIV-positive are expected to declare their status and will be counselled.

Until recently, AIDS was considered to be universally fatal, although the type and length of illness preceding death varies considerably. However, with the development of *antiretroviral drugs used in dual or triple combinations, AIDS is now perceived as a chronic disease rather than a fatal one.

AIH see artificial insemination.... aids

Bipolar Affective Disorder

(BPAD) a severe mental illness affecting about 1% of the population and causing repeated episodes of *depression, *mania, and/or *mixed affective state. Type I BPAD consists equally of depressive and manic episodes, whereas Type II BPAD consists primarily of depressive episodes with occasional phases of *hypomania. Treatment is that of the individual episode. Antidepressants and antipsychotics are used to treat depressive episodes together with mood stabilizers (e.g. *lithium) or antiepileptics. Mood stabilizers are also used to prevent or lessen future episodes. Mania is most commonly treated with benzodiazepines, antipsychotics, and mood stabilizers. ECT may be used for either episode in severe cases. To prevent future episodes many patients need combinations of mood stabilizers with *antidepressant or *antipsychotic medication. Certain types of educational *psychotherapy can be used to prevent relapse as well as to treat the individual episode. Up to 50% of BPAD patients have substance abuse problems, and many suffer from residual mood symptoms between episodes.

BI-RADS (Breast Imaging Reporting and Data System) a standardized system of terminology, report organization, assessment, and classification for mammography and ultrasound or MRI of the breast. BI-RADS reporting enables radiologists to communicate results to the referring physician clearly and consistently, with a final assessment and specific management recommendations.

The success of BI-RADS has inspired several other systems of the same kind: TI-RADS (Thyroid Imaging Reporting and Data System); LI-RADS (Liver Imaging Reporting and Data System); and PI-RADS (Prostate Imaging Reporting and Data System).... bipolar affective disorder




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