n. 1. short for *contrast medium, e.g. post-contrast CT scan. 2. the difference in the shade of grey between different tissues on a diagnostic image, such as radiograph or CT scan (see grey scale).
deterioration in renal function (of more than 25%) after administration of radiocontrast material. Development of this condition is more likely when there is pre-existing renal disease (the most important factor) or diabetes, vasoconstriction, simultaneous use of NSAIDs, and large amounts of radiocontrast are used. It is thought that the radiocontrast induces vasoconstriction in the vessels supplying the medulla of the kidney and aggravates hypoxia in this part of the kidney.... contrast nephropathy
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