Corona Health Dictionary

See HEART, DISEASES OF.... coronary thrombosis

A term applied to several structures in the body encircling an organ in the manner of a crown. The coronary arteries are the arteries of supply to the HEART which arise from the aorta, just beyond the aortic valve, and through which the blood is delivered to the muscle of the heart. Disease of the coronary arteries is a very serious condition producing various abnormal forms of heart action and the disorder, ANGINA PECTORIS.... coronary

A technique of dilating atheromatous obstructions (see ATHEROMA) in CORONARY ARTERIES by inserting a catheter with a balloon on the end into the affected artery (see also CATHETERS). It is passed through the blockage (guided by X-ray FLUOROSCOPY) and in?ated. The procedure can be carried out through a percutaneous route.... coronary angioplasty

(See also HEART.) The right coronary artery arises from the right aortic sinus and passes into the right atrio-ventricular groove to supply the right ventricle, part of the intraventricular septum and the inferior part of the left ventricle. The left coronary artery arises from the left sinus and divides into an anterior descending branch which supplies the septum and the anterior and apical parts of the heart, and the circum?ex branch which passes into the left atrio-ventricular groove and supplies the lateral posterior surfaces of the heart. Small anastomoses exist between the coronary arteries and they have the potential of enlarging if the blood-?ow through a neighbouring coronary artery is compromised. Coronary artery disease is damage to the heart caused by the narrowing or blockage of these arteries. It commonly presents as ANGINA PECTORIS or acute myocardial infarction (see HEART, DISEASES OF).... coronary arteries

A treatment for a stenosed (restricted) coronary artery (see ARTERIES). A balloon-tipped catheter (see CATHETERS) is passed through an incision in the skin of the chest into the artery of the HEART that has developed stenosis (narrowing). The balloon is aligned with the stenosed section and then in?ated to dilate the coronary artery and allow the blood to ?ow more freely.... percutaneous transluminal coronary angioplasty

Narrowing of the coronary arteries, which supply blood to the heart, leading to damage or malfunction of the heart. The most common heart disorders due to coronary artery disease are angina pectoris and myocardial infarction (heart attack). The usual cause of narrowing of the arteries is atherosclerosis, in which fatty plaques develop on the artery linings. The vessel can become totally blocked if a blood clot forms or lodges in the narrowed area. Atherosclerosis has many interrelated causes including smoking, a high-fat diet, lack of exercise, being overweight, and raised blood cholesterol levels. Other factors include a genetic predisposition and diseases such as diabetes mellitus and hypertension.

The first symptom of coronary artery disease is frequently the chest pain of angina. Treatment is with drugs such as glyceryl trinitrate and other nitrate drugs, beta-blockers, calcium channel blockers, potassium channel activators, and vasodilator drugs. If drug treatment fails to relieve the symptoms, or there is extensive narrowing of the coronary

arteries, blood flow may be improved by balloon angioplasty or coronary artery bypass surgery.... coronary artery disease

A specialist ward for the care of acutely ill patients who may be suffering, or who have suffered, a myocardial infarction (heart attack) or another serious cardiovascular disorder.... coronary care unit

The cause of: coronary occlusion, coronary blockage, coronary thrombosis. A heart attack occurs when a coronary artery becomes blocked by swellings composed, among other things, of cholesterol. Such swellings may obstruct the flow of blood leading to a blood clot (thrombus). Cholesterol is a major cause of CHD.

Coronary thrombosis is more common in the West because of its preference for animal fats; whereas in the East fats usually take the form of vegetable oils – corn, sunflower seed, sesame, etc. Fatty deposits (atheroma) form in the wall of the coronary artery, obstructing blood-flow. Vessels narrowed by atheroma and by contact with calcium and other salts become hard and brittle (arterio-sclerosis) and are easily blocked. Robbed of oxygen and nutrients heart muscle dies and is replaced by inelastic fibrous (scar) tissue which robs the heart of its maximum performance.

Severe pain and collapse follow a blockage. Where only a small branch of the coronary arterial tree is affected recovery is possible. Cause of the pain is lack of oxygen (Vitamin E). Incidence is highest among women over 40 who smoke excessively and who take The Pill.

The first warning sign is breathlessness and anginal pain behind the breastbone which radiates to arms and neck. Sensation as if the chest is held in a vice. First-line agent to improve flow of blood – Cactus.

For cholesterol control target the liver. Coffee is a minor risk factor.

Measuring hair calcium levels is said to predict those at risk of coronary heart disease. Low hair concentrations may be linked with poor calcium metabolism, high aortic calcium build-up and the formation of plagues. (Dr Allan MacPherson, nutritionist, Scottish Agricultural College, Ayr, Scotland)

Evidence has been advanced that a diagonal ear lobe crease may be a predictor for coronary heart disease. (American Journal of Cardiology, Dec. 1992)

Tooth decay is linked to an increased risk of coronary heart disease and mortality, particularly in young men. (Dr Frank De Stefano, Marshfield Medical Research Foundation, Wisconsin, USA) Treatment. Urgency. Send for doctor or suitably qualified practitioner. Absolute bedrest for 3 weeks followed by 3 months convalescence. Thereafter: adapt lifestyle to slower tempo and avoid undue exertion. Stop smoking. Adequate exercise. Watch weight.

Cardiotonics: Motherwort, Hawthorn, Mistletoe, Rosemary. Ephedra, Lily of the Valley, Broom.

Cardiac vasodilators relax tension on the vessels by increasing capacity of the arteries to carry more blood. Others contain complex glycosides that stimulate or relax the heart at its work. Garlic is strongly recommended as a preventative of CHD.

Hawthorn, vasodilator and anti-hypertensive, is reputed to dissolve deposits in thickened and sclerotic arteries BHP (1983). It is believed to regulate the balance of lipids (body fats) one of which is cholesterol.

Serenity tea. Equal parts: Motherwort, Lemon Balm, Hawthorn leaves or flowers. 1 heaped teaspoon to each cup boiling water; infuse 5-15 minutes; 1 cup freely.

Decoction. Combine equal parts: Broom, Lily of the Valley, Hawthorn. 1-2 teaspoons to each cup water gently simmered 20 minutes. Half-1 cup freely.

Tablets/capsules. Hawthorn, Motherwort, Cactus, Mistletoe, Garlic.

Practitioner. Formula. Hawthorn 20ml; Lily of the Valley 10ml; Pulsatilla 5ml; Stone root 5ml; Barberry 5ml. Tincture Capsicum 1ml. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Thrice daily in water or honey.

Prevention: Vitamin E – 400iu daily.

Diet. See: DIET – HEART AND CIRCULATION.

Supplements. Daily. Vitamin C, 2g. Vitamin E possesses anti-clotting properties, 400iu. Broad spectrum multivitamin and mineral including chromium, magnesium selenium, zinc, copper.

Acute condition. Strict bed-rest; regulate bowels; avoid excessive physical and mental exertion. Meditation and relaxation techniques dramatically reduce coronary risk. ... coronary heart disease

When coronary arteries, narrowed by disease, cannot supply the heart muscle with su?cient blood, the cardiac circulation may be improved by grafting a section of vein from the leg to bypass the obstruction. Around 10,000 people in the United Kingdom have this operation annually and the results are usually good. It is a major procedure that lasts several hours and requires the heart to be stopped temporarily, with blood circulation and oxygenation taken over by a HEART-LUNG MACHINE.... coronary artery vein bypass grafting (cavbg)

A specialised hospital unit equipped and sta?ed to provide intensive care (see INTENSIVE THERAPY UNIT (ITU)) for patients who have had severe heart attacks or undergone surgery on the heart.... coronary care unit (ccu)

RNA viruses causing the common cold Coronatae The taxonomic order of grooved jellyfish.... coronavirus

Coronaviruses – so-called because in electron micrographs the spikes projecting from the virus resemble a crown – are a group of viruses which have been isolated from people with common colds (see COLD, COMMON) and have also been shown to produce common colds under experimental conditions. Their precise signi?cance in the causation of the common cold is still undetermined.... coronaviruses

staff.

Synonym: E. divaricata (L.) Alston. Tabernaemontana coronaria R.Br.

Family: Apocynaceae.

Habitat: Throughout the sub- Himalayan tract from Garhwal eastwards to Assam and Bengal, extending southwards to North Circars.

English: East Indian Rosebay.

Ayurvedic: Nandivrksha, Tagar.

Siddha/Tamil: Nandiyaavattam.

Action: Topically anodyne; chewed for relief of toothache; administered as a vermicide. Various parts of the plant are used in the indigenous system of medicine for skin diseases and cancer.

The plant from Sri Lanka and Pakistan contains several indole alkaloids, including voacristine.

Isovoacristic hydrochloride caused bradycardia in frogs and rabbits. The decoction of leaves exhibits antihypertensive and diuretic activity. Taberson- ine, reported in the flowers, showed hypotensive effect on anaesthetized cats.

The most abundant alkaloids in stem cortex are tabernaemontanine, dregamine and 20-epi ervatamine.... ervataemia coronaria

Either of the 2 main arteries that supply the tissues of the heart with oxygen-rich blood. These are

known as the left and right main coronary arteries and arise directly from the aorta. The term coronary artery is also applied to any of the arteries that branch off from the main coronary arteries, such as the left circumflex artery and the left anterior descending artery. Blockage of a coronary artery as a result of atherosclerosis can lead to myocardial infarction.

(See also coronary artery disease.)... coronary artery

A major heart operation to bypass narrowed or blocked coronary arteries using additional blood vessels (such as a mammary artery) to improve blood flow to the heart muscle. This operation is used when symptoms of coronary artery disease have not been relieved by drugs or balloon angioplasty.

Before surgery, sites of blockage in the arteries are identified using angiography. In some cases, minimally invasive surgery can be used, avoiding the need to stop the heart and use a heart–lung machine during the operation. The long term outlook after a bypass is good, but the grafted vessels may also eventually become blocked by atherosclerosis.... coronary artery bypass

Koenig.

Family: Zingiberaceae.

Habitat: Throughout the moist parts of India, up to 2,000 m. Also grown in gardens of Assam and South India.

English: Ginger Lily.

Ayurvedic: Shati (related species).

Action: Anti-inflammatory, antirheumatic, febrifuge, tranquilizer.

The rhizomes gave furanoditerpene, hedychenone, an anti-inflammatory principle, also cytotoxic principles as labdane-type diterpenes.

The essential oil from rhizome shows anthelmintic and mild tranquil- izing property. The essential oil contains alpha- and beta-pinene, limo- nene, carene, and its oxide, linalool and elemole in varying concentrations. The essential oil also gave borneol, methyl salicylate, eugenol and methy- lanthranilate.... hedychium coronarium

(Jacq.) Willd.

Synonym: T. divaricata (L.) R. Br. Ervatamia coronaria (Jacq.) Staph. E. divaricata (L.) Burkill.

Family: Apocynaceae.

Habitat: Sub-Himalayan tract. Cultivated in gardens.

English: East Indian Rosebay.

Ayurvedic: Tagar, Nandivriksha (The Wealth of India); Nandi Pushpa. (Tagar is equated with Valeriana hardwickii and Nandivrksha with Cedrela toona.)

Siddha/Tamil: Nandiyavattam.

Folk: Tengari, Chaandani.

Action: Leaves—milky juice, antiinflammatory; applied to wounds. Flowers—mixed with oil, used in skin diseases. Root—acrid, anodyne; relieves toothache, also used as a vermicide.

Various parts of the plant are used in the indigenous system of medicine for the treatment of skin diseases and cancer. A decoction of leaves is used as antihypertensive and diuretic.

The plant from Sri Lanka (root, leaves and flowers) contain several indole alkaloids including voacristine, voacangine, coronaridine, vobasine, tabernaemontanine and dregamine. Isovoacristic hydrochloride, found in the plant, caused bradycardia in frogs and rabbits. The flowers contain an alkaloid tabersonine which is reported to show hypotensive effect on anaesthetized cats.

Coronaridine showed autonomic as well as CNS activity when tested for biological action in animals. It produced analgesia and was effective in suppressing foot-shock-induced rage in mice.

Indole alkaloid (I) inhibited HC1- induced ulcer in mice by 48.8%.

The crude alkaloid extracts of the leaves, bark and flowers exhibit antibacterial activity against Staphylococcus aureus.... tabernaemontana coronaria

a combination of angina (unstable or stable), non-S–T elevation *myocardial infarction (NSTEMI), and S–T elevation myocardial infarction (STEMI). It implies the presence of coronary artery disease.... acute coronary syndrome

adj. relating to the crown of the head or of a tooth. The coronal plane divides the body into dorsal and ventral parts (see illustration overleaf).... coronal

see suture.... coronal suture

1. a series of radiating fibres between the cerebral cortex and the internal capsule of the brain. 2. a layer of follicle cells that surrounds a freshly ovulated ovum. The cells are elongated radially to the ovum when seen in section.... corona radiata

(CABG) *coronary revascularization in which a segment of a coronary artery narrowed by atheroma is bypassed by an *autologous section of healthy saphenous vein or internal mammary artery at *thoracotomy. The improved blood flow resulting from one or more such grafts relieves *angina pectoris and reduces the risk of *myocardial infarction. Recently developed techniques of *minimally invasive surgery have enabled the operation to be performed without the need for thoracotomy.... coronary artery bypass graft

the restoration of blood flow to ischaemic heart muscle (see ischaemia) by *coronary angioplasty and *stenting or by a *coronary artery bypass graft.... coronary revascularization

an X-ray technique for examination of the coronary arteries, often taken to also include examination of the chambers of the heart. A catheter is introduced via the radial artery at the wrist or the femoral artery at the groin and manipulated into the heart under X-ray control. *Contrast medium is then injected to outline the ventricles and coronary arteries. Digital video images are recorded during contrast-medium injection. Coronary angiography is used to diagnose cardiac disease, specifically narrowing or blockage in the coronary arteries, and plan treatment by surgery or radiological interventional techniques (see coronary artery bypass graft; percutaneous coronary intervention). It has now largely been replaced by CT coronary angiography.... coronary angiography

(PCI) treatment of coronary artery disease delivered by cardiac *catheterization. This usually means *coronary angioplasty followed by insertion of a coronary *stent, but also includes more specialized procedures, such as rotational *atherectomy (rotablation). Primary PCI refers to the use of PCI as the first-line treatment to relieve coronary obstruction in S-T elevation *myocardial infarction, rather than *thrombolysis. Rescue PCI is used in the event of unsuccessful thrombolysis.... percutaneous coronary intervention