Delusions Health Dictionary

Delusions: From 1 Different Sources


An irrational and usually unshakeable belief (idée ?xe) peculiar to some individuals. They fail to respond to reasonable argument and the delusion is often paranoid in character with a belief that a person or persons is/are persecuting them. The existence of a delusion, of such a nature as to in?uence conduct seriously, is one of the most important signs in reaching a decision to arrange for the compulsory admission of the patient to hospital for observation. (See MENTAL ILLNESS.)
Health Source: Medical Dictionary
Author: Health Dictionary

Paranoia

A condition whose main characteristic is the delusion (see DELUSIONS) that other people are (in an unclear way) connected to the affected individual. A sufferer from paranoia constructs a complex of beliefs based on his or her interpretation of chance remarks or events. Persecution, love, jealousy and self-grandeur are among the emotions evoked. Acute paranoia – a history of less than six months – may be the result of drastic changes in a person’s environment, such as war, imprisonment, famine or even leaving home for the ?rst time. Chronic paranoia may be caused by brain damage, substance abuse (including alcohol and cannbis), SCHIZOPHRENIA or severe DEPRESSION. Those affected may become constantly suspicious and angry and tend to live an isolated existence, exhibiting di?cult and odd behaviour. Often believing themselves to be normal, they do not seek treatment. If treated early with antipsychotic drugs, they often recover; if not, the delusions and accompanying erratic behaviour become entrenched. (See MENTAL ILLNESS.)... paranoia

Psychosis

One of a group of mental disorders in which the affected person loses contact with reality. Thought processes are so disturbed that the person does not always realise that he or she is ill. Symptoms include DELUSIONS, HALLUCINATIONS, loss of emotion, MANIA, DEPRESSION, poverty of thought and seriously abnormal behaviour. Psychoses include SCHIZOPHRENIA, MANIC DEPRESSION and organically based mental disorders. (See also MENTAL ILLNESS.)... psychosis

Schizophrenia

An overall title for a group of psychiatric disorders typ?ed by disturbances in thinking, behaviour and emotional response. Despite its inaccurate colloquial description as ‘split personality’, schizophrenia should not be confused with MULTIPLE PERSONALITY DISORDER. The illness is disabling, running a protracted course that usually results in ill-health and, often, personality change. Schizophrenia is really a collection of symptoms and signs, but there is no speci?c diagnostic test for it. Similarity in the early stages to other mental disorders, such as MANIC DEPRESSION, means that the diagnosis may not be con?rmed until its response to treatment and its outcome can be assessed and other diseases excluded.

Causes There is an inherited element: parents, children or siblings of schizophrenic sufferers have a one in ten chance of developing the disorder; a twin has a 50 per cent chance if the other twin has schizophrenia. Some BRAIN disorders such as temporal lobe EPILEPSY, tumours and ENCEPHALITIS seem to be linked with schizophrenia. Certain drugs – for example, AMPHETAMINES – can precipitate schizophrenia and DOPAMINE-blocking drugs often relieve schizophrenic symptoms. Stress may worsen schizophrenia and recreational drugs may trigger an attack.

Symptoms These usually develop gradually until the individual’s behaviour becomes so distrubing or debilitating that work, relationships and basic activities such as eating and sleeping are interrupted. The patient may have disturbed perception with auditory HALLUCINATIONS, illogical thought-processes and DELUSIONS; low-key emotions (‘?at affect’); a sense of being invaded or controlled by outside forces; a lack of INSIGHT and inability to acknowledge reality; lethargy and/or agitation; a disrespect for personal appearance and hygiene; and a tendency to act strangely. Violence is rare although some sufferers commit violent acts which they believe their ‘inner voices’ have commanded.

Relatives and friends may try to cope with the affected person at home, but as severe episodes may last several months and require regular administration of powerful drugs – patients are not always good at taking their medication

– hospital admission may be necessary.

Treatment So far there is no cure for schizophrenia. Since the 1950s, however, a group of drugs called antipsychotics – also described as NEUROLEPTICS or major tranquillisers – have relieved ?orid symptoms such as thought disorder, hallucinations and delusions as well as preventing relapses, thus allowing many people to leave psychiatric hospitals and live more independently outside. Only some of these drugs have a tranquillising e?ect, but their sedative properties can calm patients with an acute attack. CHLORPROMAZINE is one such drug and is commonly used when treatment starts or to deal with an emergency. Halperidol, tri?uoperazine and pimozide are other drugs in the group; these have less sedative effects so are useful in treating those whose prominent symptoms are apathy and lethargy.

The antipsychotics’ mode of action is by blocking the activity of DOPAMINE, the chemical messenger in the brain that is faulty in schizophrenia. The drugs quicken the onset and prolong the remission of the disorder, and it is very important that patients take them inde?nitely. This is easier to ensure when a patient is in hospital or in a stable domestic environment.

CLOZAPINE – a newer, atypical antipsychotic drug – is used for treating schizophrenic patients unresponsive to, or intolerant of, conventional antipsychotics. It may cause AGRANULOCYTOSIS and use is con?ned to patients registered with the Clorazil (the drug’s registered name) Patient Monitoring Service. Amisulpride, olanzapine, quetiapine, risperidone, sertindole and zotepine are other antipsychotic drugs described as ‘atypical’ by the British National Formulary; they may be better tolerated than other antipsychotics, and their varying properties mean that they can be targeted at patients with a particular grouping of symptoms. They should, however, be used with caution.

The welcome long-term shift of mentally ill patients from large hospitals to community care (often in small units) has, because of a lack of resources, led to some schizophrenic patients not being properly supervised with the result that they fail to take their medication regularly. This leads to a recurrence of symptoms and there have been occasional episodes of such patients in community care becoming a danger to themselves and to the public.

The antipsychotic drugs are powerful agents and have a range of potentially troubling side-effects. These include blurred vision, constipation, dizziness, dry mouth, limb restlessness, shaking, sti?ness, weight gain, and in the long term, TARDIVE DYSKINESIA (abnormal movements and walking) which affects about 20 per cent of those under treatment. Some drugs can be given by long-term depot injection: these include compounds of ?upenthixol, zuclopenthixol and haloperidol.

Prognosis About 25 per cent of sufferers recover fully from their ?rst attack. Another 25 per cent are disabled by chronic schizophrenia, never recover and are unable to live independently. The remainder are between these extremes. There is a high risk of suicide.... schizophrenia

Delirium

A condition of altered consciousness in which there is disorientation (as in a confusional state), incoherent talk and restlessness but with hallucination, illusions or delusions also present.

Delirium (confusion) In some old people, acute confusion is a common e?ect of physical illness. Elderly people are often referred to as being ‘confused’; unfortunately this term is often inappropriately applied to a wide range of eccentricities of speech and behaviour as if it were a diagnosis. It can be applied to a patient with the early memory loss of DEMENTIA – forgetful, disorientated and wandering; to the dejected old person with depression, often termed pseudo-dementia; to the patient whose consciousness is clouded in the delirium of acute illness; to the paranoid deluded sufferer of late-onset SCHIZOPHRENIA; or even to the patient presenting with the acute DYSPHASIA and incoherence of a stroke. Drug therapy may be a cause, especially in the elderly.

Delirium tremens is the form of delirium most commonly due to withdrawal from alcohol, if a person is dependent on it (see DEPENDENCE). There is restlessness, fear or even terror accompanied by vivid, usually visual, hallucinations or illusions. The level of consciousness is impaired and the patient may be disorientated as regards time, place and person.

Treatment is, as a rule, the treatment of causes. (See also ALCOHOL.) As the delirium in fevers is due partly to high temperature, this should be lowered by tepid sponging. Careful nursing is one of the keystones of successful treatment, which includes ensuring that ample ?uids are taken and nutrition is maintained.... delirium

Hypochondriasis

Obsession with the body’s functions and a DELUSION of ill health, often severe, such that patients may believe they have a brain tumour or incurable insanity. Furthermore, patients may believe that they have infected others, or that their children have inherited the condition. It is a characteristic feature of DEPRESSION, but may also occur in SCHIZOPHRENIA, when the delusions may be secondary to bodily HALLUCINATIONS, and a sense of subjective change. Chronic hypochondriasis may be the result of an abnormal personality development: for example, the insecure, bodily-conscious person. Delusional preoccupations with the body – usually the face – may occur, such that the patient is convinced that his or her face is twisted, or dis?gured with acne.

Treatment Hypochondriacal patients may also develop physical illness, and any new symptoms must always be carefully evaluated. In most patients the condition is secondary, and treatment should be directed to the underlying depression or schizophrenia. In the rare cases of primary hypochondriasis, supportive measures are the mainstay of treatment.... hypochondriasis

Depression

Depression is a word that is regularly misused. Most people experience days or weeks when they feel low and fed up (feelings that may recur), but generally they get over it without needing to seek medical help. This is not clinical depression, best de?ned as a collection of psychological symptoms including sadness; unhappy thoughts characterised by worry, poor self-image, self-blame, guilt and low self-con?dence; downbeat views on the future; and a feeling of hopelessness. Su?erers may consider suicide, and in severe depression may soon develop HALLUCINATIONS and DELUSIONS.

Doctors make the diagnosis of depression when they believe a patient to be ill with the latter condition, which may affect physical health and in some instances be life-threatening. This form of depression is common, with up to 15 per cent of the population suffering from it at any one time, while about 20 per cent of adults have ‘medical’ depression at some time during their lives – such that it is one of the most commonly presenting disorders in general practice. Women seem more liable to develop depression than men, with one in six of the former and one in nine of the latter seeking medical help.

Manic depression is a serious form of the disorder that recurs throughout life and is manifested by bouts of abnormal elation – the manic stage. Both the manic and depressive phases are commonly accompanied by psychotic symptoms such as delusions, hallucinations and a loss of sense of reality. This combination is sometimes termed a manic-depressive psychosis or bipolar affective disorder because of the illness’s division into two parts. Another psychiatric description is the catch-all term ‘affective disorder’.

Symptoms These vary with the illness’s severity. Anxiety and variable moods are the main symptoms in mild depression. The sufferer may cry without any reason or be unresponsive to relatives and friends. In its more severe form, depression presents with a loss of appetite, sleeping problems, lack of interest in and enjoyment of social activities, tiredness for no obvious reason, an indi?erence to sexual activity and a lack of concentration. The individual’s physical and mental activities slow down and he or she may contemplate suicide. Symptoms may vary during the 24 hours, being less troublesome during the latter part of the day and worse at night. Some people get depressed during the winter months, probably a consequence of the long hours of darkness: this disorder – SEASONAL AFFECTIVE DISORDER SYNDROME, or SADS – is thought to be more common in populations living in areas with long winters and limited daylight. Untreated, a person with depressive symptoms may steadily worsen, even withdrawing to bed for much of the time, and allowing his or her personal appearance, hygiene and environment to deteriorate. Children and adolescents may also suffer from depression and the disorder is not always recognised.

Causes A real depressive illness rarely has a single obvious cause, although sometimes the death of a close relative, loss of employment or a broken personal relationship may trigger a bout. Depression probably has a genetic background; for instance, manic depression seems to run in some families. Viral infections sometimes cause depression, and hormonal disorders – for example, HYPOTHYROIDISM or postnatal hormonal disturbances (postnatal depression) – will cause it. Di?cult family or social relations can contribute to the development of the disorder. Depression is believed to occur because of chemical changes in the transmission of signals in the nervous system, with a reduction in the neurochemicals that facilitate the passage of messages throughout the system.

Treatment This depends on the type and severity of the depression. These are three main forms. PSYCHOTHERAPY either on a one-to-one basis or as part of a group: this is valuable for those whose depression is the result of lifestyle or personality problems. Various types of psychotherapy are available. DRUG TREATMENT is the most common method and is particularly helpful for those with physical symptoms. ANTIDEPRESSANT DRUGS are divided into three main groups: TRICYCLIC ANTIDEPRESSANT DRUGS (amitriptyline, imipramine and dothiepin are examples); MONOAMINE OXIDASE INHIBITORS (MAOIS) (phenelzine, isocarboxazid and tranylcypromine are examples); and SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIS) (?uoxetine – well known as Prozac®, ?uvoxamine and paroxetine are examples). For manic depression, lithium carbonate is the main preventive drug and it is also used for persistent depression that fails to respond to other treatments. Long-term lithium treatment reduces the likelihood of relapse in about 80 per cent of manic depressives, but the margin between control and toxic side-effects is narrow, so the drug must be carefully supervised. Indeed, all drug treatment for depression needs regular monitoring as the substances have powerful chemical properties with consequential side-effects in some people. Furthermore, the nature of the illness means that some sufferers forget or do not want to take the medication. ELECTROCONVULSIVE THERAPY (ECT) If drug treatments fail, severely depressed patients may be considered for ECT. This treatment has been used for many years but is now only rarely recommended. Given under general anaesthetic, in appropriate circumstances, ECT is safe and e?ective and may even be life-saving, though temporary impairment of memory may occur. Because the treatment was often misused in the past, it still carries a reputation that worries patients and relatives; hence careful assessment and counselling are essential before use is recommended.

Some patients with depression – particularly those with manic depression or who are a danger to themselves or to the public, or who are suicidal – may need admission to hospital, or in severe cases to a secure unit, in order to initiate treatment. But as far as possible patients are treated in the community (see MENTAL ILLNESS).... depression

Delusion

A fixed, irrational idea not shared by others and not responding to reasoned argument. The idea in a paranoid delusion involves persecution or jealousy. For instance, a person may falsely believe that he or she is being poisoned (see paranoia). Persistent delusions are a sign of serious mental illness, most notably schizophrenia and manic–depressive illness. (See also hallucination; illusion.)... delusion

Folie à Deux

A French term that is used to describe the unusual occurrence of 2 people sharing the same psychotic illness (see psychosis). Commonly, the 2 are closely related and share one or more paranoid delusions. If the sufferers

are separated, one of them almost always quickly loses the symptoms, which have been imposed by the dominant, and genuinely psychotic, partner.... folie à deux

Mania

A mental disorder characterized by episodes of overactivity, elation, or irritability. Mania usually occurs as part of a manic–depressive illness.

Symptoms may include extravagant spending, repeatedly starting new tasks; sleeping less; increased appetite for food, alcohol, sex, and exercise; outbursts of inappropriate anger, laughter, or sudden socializing; and delusions of grandeur. If symptoms are mild, the condition is called hypomania.

Severe mania usually needs treatment in hospital with antipsychotic drugs. Relapses may be prevented by taking lithium or carbamazepine.... mania

Alzheimer’s Disease

A progressive condition in which nerve cells in the brain degenerate and the brain shrinks. Alzheimer’s disease is the most common cause of dementia. Onset is uncommon before the age of 60.

Early onset Alzheimer’s disease, in which symptoms develop before age 60, is inherited as a dominant disorder. Late onset Alzheimer’s disease is associated with a number of genes, including 3 that

are responsible for the production of the blood protein apolipoprotein E. These genes also result in the deposition of a protein called beta amyloid in the brain. Other chemical abnormalities may include deficiency of the neurotransmitter acetylcholine.

The features of Alzheimer’s disease vary, but there are 3 broad stages. At first, the person becomes increasingly forgetful, and problems with memory may cause anxiety and depression. In the 2nd stage, loss of memory, particularly for recent events, gradually becomes more severe, and there may be disorientation as to time or place. The person’s concentration and numerical ability decline, and there is noticeable dysphasia (inability to find the right word). Anxiety increases, mood changes are unpredictable, and personality changes may occur. Finally, confusion becomes profound. There may be symptoms of psychosis, such as hallucinations and delusions. Signs of nervous system disease, such as abnormal reflexes and faecal or urinary incontinence, begin to develop.

Alzheimer’s disease is usually diagnosed from the symptoms, but tests including blood tests and CT scanning or MRI of the brain may be needed to exclude treatable causes of dementia.

The most important aspect of treatment for Alzheimer’s disease is the provision of suitable nursing and social care for sufferers and support for their relatives. Tranquillizer drugs can often improve difficult behaviour and help with sleep. Treatment with drugs such as donepezil and rivastigmine may slow the progress of the disease for a time, but side effects such as nausea and dizziness may occur.... alzheimer’s disease

Amfetamine Drugs

A group of stimulant drugs used mainly in the treatment of narcolepsy (a rare disorder characterized by excessive sleepiness).

In high doses, amfetamines can cause tremor, sweating, anxiety, and sleeping problems. Delusions, hallucinations, high blood pressure, and seizures may also occur. Prolonged use may produce tolerance and drug dependence.

Amfetamines are often abused for their stimulant effect.... amfetamine drugs

Hebephrenia

A form of SCHIZOPHRENIA that comes on in youth and is marked by depression and gradual failure of mental faculties with egotistic and self-centred delusions.... hebephrenia

Korsakoff’s Syndrome

A form of mental disturbance occurring in chronic alcoholism and other toxic states, such as URAEMIA, lead poisoning and cerebral SYPHILIS. Its special features are talkativeness with delusions in regard to time and place – the patient, although clear in other matters, imagining that he or she has recently made journeys.... korsakoff’s syndrome

Mental Illness

De?ned simply, this is a disorder of the brain’s processes that makes the sufferer feel or seem ill, and may prevent that person from coping with daily life. Psychiatrists – doctors specialising in diagnosing and treating mental illness – have, however, come up with a range of much more complicated de?nitions over the years.

Psychiatrists like to categorise mental illnesses because mental signs and symptoms do occur together in clusters or syndromes, each tending to respond to certain treatments. The idea that illnesses can be diagnosed simply by recognising their symptom patterns may not seem very scienti?c in these days of high technology. For most common mental illnesses, however, this is the only method of diagnosis; whatever is going wrong in the brain is usually too poorly understood and too subtle to show up in laboratory tests or computed tomography scans of the brain. And symptom-based definitions of mental illnesses are, generally, a lot more meaningful than the vague lay term ‘nervous breakdown’, which is used to cover an attack of anything from AGORAPHOBIA to total inability to function.

There is still a lot to learn about the workings of the brain, but psychiatry has developed plenty of practical knowledge about the probable causes of mental illness, ways of relieving symptoms, and ways of aiding recovery. Most experts now believe that mental illnesses generally arise from di?erent combinations of inherited risk and psychological STRESS, sometimes with additional environmental exposure – for example, viruses, drugs or ALCOHOL.

The range of common mental illnesses includes anxiety states, PHOBIA, DEPRESSION, alcohol and drug problems, the EATING DISORDERS anorexia and bulimia nervosa, MANIC DEPRESSION, SCHIZOPHRENIA, DEMENTIA, and a group of problems related to coping with life that psychiatrists call personality disorders.

Of these mental illnesses, dementia is the best understood. It is an irreversible and fatal form of mental deterioration (starting with forgetfulness and eventually leading to severe failure of all the brain’s functions), caused by rapid death of brain cells and consequent brain shrinkage. Schizophrenia is another serious mental illness which disrupts thought-processes, speech, emotions and perception (how the brain handles signals from the ?ve senses). Manic depression, in which prolonged ‘highs’ of extremely elevated mood and overexcitement alternate with abject misery, has similar effects on the mental processes. In both schizophrenia and manic depression the sufferer loses touch with reality, develops unshakeable but completely unrealistic ideas (delusions), and hallucinates (vividly experiences sensations that are not real, e.g. hears voices when there is nobody there). This triad of symptoms is called psychosis and it is what lay people, through fear and lack of understanding, sometimes call lunacy, madness or insanity.

The other mental illnesses mentioned above are sometimes called neuroses. But the term has become derogatory in ordinary lay language; indeed, many people assume that neuroses are mild disorders that only affect weak people who cannot ‘pull themselves together’, while psychoses are always severe. In reality, psychoses can be brief and reversible and neuroses can cause lifelong disability.

However de?ned and categorised, mental illness is a big public-health problem. In the UK, up to one in ?ve women and around one in seven men have had mental illness. About half a million people in Britain suffer from schizophrenia: it is three times commoner than cancer. And at any one time, up to a tenth of the adult population is ill with depression.

Treatment settings Most people with mental-health problems get the help they need from their own family doctor(s), without ever seeing a psychiatrist. General practictitioners in Britain treat nine out of ten recognised mental-health problems and see around 12 million adults with mental illness each year. Even for the one in ten of these patients referred to psychiatrists, general practitioners usually handle those problems that continue or recur.

Psychiatrists, psychiatric nurses, social workers, psychologists, counsellors and therapists often see patients at local doctors’ surgeries and will do home visits if necessary. Community mental-health centres – like general-practice health centres but catering solely for mental-health problems – o?er another short-cut to psychiatric help. The more traditional, and still more common, route to a psychiatrist for many people, however, is from the general practititioner to a hospital outpatient department.

Specialist psychiatric help In many ways, a visit to a psychiatrist is much like any trip to a hospital doctor – and, indeed, psychiatric clinics are often based in the outpatient departments of general hospitals. First appointments with psychiatrists can last an hour or more because the psychiatrist – and sometimes other members of the team such as nurses, doctors in training, and social workers – need to ask lots of questions and record the whole consultation in a set of con?dential case notes.

Psychiatric assessment usually includes an interview and an examination, and is sometimes backed up by a range of tests. The interview begins with the patient’s history – the personal story that explains how and, to some extent, why help is needed now. Mental-health problems almost invariably develop from a mixture of causes – emotional, social, physical and familial – and it helps psychiatrists to know what the people they see are normally like and what kind of lives they have led. These questions may seem unnecessarily intrusive, but they allow psychiatrists to understand patients’ problems and decide on the best way to help them.

The next stage in assessment is the mental-state examination. This is how psychiatrists examine minds, or at least their current state. Mental-state examination entails asking more questions and using careful observation to assess feelings, thoughts and mental symptoms, as well as the way the mind is working (for example, in terms of memory and concentration). During ?rst consultations psychiatrists usually make diagnoses and explain them. The boundary between a life problem that will clear up spontaneously and a mental illness that needs treatment is sometimes quite blurred; one consultation may be enough to put the problem in perspective and help to solve it.

Further assessment in the clinic may be needed, or some additional tests. Simple blood tests can be done in outpatient clinics but other investigations will mean referral to another department, usually on another day.

Further assessment and tests

PSYCHOLOGICAL TESTS Psychologists work in or alongside the psychiatric team, helping in both assessment and treatment. The range of psychological tests studies memory, intelligence, personality, perception and capability for abstract thinking. PHYSICAL TESTS Blood tests and brain scans may be useful to rule out a physical illness causing psychological symptoms. SOCIAL ASSESSMENT Many patients have social diffculties that can be teased out and helped by a psychiatric social worker. ‘Approved social workers’ have special training in the use of the Mental Health Act, the law that authorises compulsory admissions to psychiatric hospitals and compulsory psychiatric treatments. These social workers also know about all the mental-health services o?ered by local councils and voluntary organisations, and can refer clients to them. The role of some social workers has been widened greatly in recent years by the expansion of community care. OCCUPATIONAL THERAPY ASSESSMENT Mental-health problems causing practical disabilities – for instance, inability to work, cook or look after oneself – can be assessed and helped by occupational therapists.

Treatment The aims of psychiatric treatment are to help sufferers shake o?, or at least cope with, symptoms and to gain or regain an acceptable quality of life. A range of psychological and physical treatments is available.

COUNSELLING This is a widely used ‘talking cure’, particularly in general practice. Counsellors listen to their clients, help them to explore feelings, and help them to ?nd personal and practical solutions to their problems. Counsellors do not probe into clients’ pasts or analyse them. PSYCHOTHERAPY This is the best known ‘talking cure’. The term psychotherapy is a generalisation covering many di?erent concepts. They all started, however, with Sigmund Freud (see FREUDIAN THEORY), the father of modern psychotherapy. Freud was a doctor who discovered that, as well as the conscious thoughts that guide our feelings and actions, there are powerful psychological forces of which we are not usually aware. Applying his theories to his patients’ freely expressed thoughts, Freud was able to cure many illnesses, some of which had been presumed completely physical. This was the beginning of individual analytical psychotherapy, or PSYCHOANALYSIS. Although Freud’s principles underpin all subsequent theories about the psyche, many di?erent schools of thought have emerged and in?uenced psychotherapists (see ADLER; JUNGIAN ANALYSIS; PSYCHOTHERAPY). BEHAVIOUR THERAPY This springs from theories of human behaviour, many of which are based on studies of animals. The therapists, mostly psychologists, help people to look at problematic patterns of behaviour and thought, and to change them. Cognitive therapy is very e?ective, particularly in depression and eating disorders. PHYSICAL TREATMENTS The most widely used physical treatments in psychiatry are drugs. Tranquillising and anxiety-reducing BENZODIAZEPINES like diazepam, well known by its trade name of Valium, were prescribed widely in the 1960s and 70s because they seemed an e?ective and safe substitute for barbiturates. Benzodiazepines are, however, addictive and are now recommended only for short-term relief of anxiety that is severe, disabling, or unacceptably distressing. They are also used for short-term treatment of patients drying out from alcohol.

ANTIDEPRESSANT DRUGS like amitriptyline and ?uoxetine are given to lift depressed mood and to relieve the physical symptoms that sometimes occur in depression, such as insomnia and poor appetite. The side-effects of antidepressants are mostly relatively mild, when recommended doses are not exceeded – although one group, the monoamine oxidase inhibitors, can lead to sudden and dangerous high blood pressure if taken with certain foods.

Manic depression virtually always has to be treated with mood-stabilising drugs. Lithium carbonate is used in acute mania to lower mood and stop psychotic symptoms; it can also be used in severe depression. However lithium’s main use is to prevent relapse in manic depression. Long-term unwanted effects may include kidney and thyroid problems, and short-term problems in the nervous system and kidney may occur if the blood concentration of lithium is too high – therefore it must be monitored by regular blood tests. Carbamazepine, a treatment for EPILEPSY, has also been found to stabilise mood, and also necessitates blood tests.

Antipsychotic drugs, also called neuroleptics, and major tranquillisers are the only e?ective treatments for relieving serious mental illnesses with hallucinations and delusions. They are used mainly in schizophrenia and include the short-acting drugs chlorpromazine and clozapine as well as the long-lasting injections given once every few weeks like ?uphenazine decanoate. In the long term, however, some of the older antipsychotic drugs can cause a brain problem called TARDIVE DYSKINESIA that affects control of movement and is not always reversible. And the antipsychotic drugs’ short-term side-effects such as shaking and sti?ness sometimes have to be counteracted by other drugs called anticholinergic drugs such as procyclidine and benzhexol. Newer antipsychotic drugs such as clozapine do not cause tardive dyskinesia, but clozapine cannot be given as a long-lasting injection and its concentration in the body has to be monitored by regular blood tests to avoid toxicity. OTHER PHYSICAL TREATMENTS The other two physical treatments used in psychiatry are particularly controversial: electroconvulsive therapy (ECT) and psychosurgery. In ECT, which can be life-saving for patients who have severe life-threatening depression, a small electric current is passed through the brain to induce a ?t or seizure. Before the treatment the patient is anaesthetised and given a muscle-relaxing injection that reduces the magnitude of the ?t to a slight twitching or shaking. Scientists do not really understand how ECT works, but it does, for carefully selected patients. Psychosurgery – operating on the brain to alleviate psychiatric illness or di?cult personality traits – is extremely uncommon these days. Stereo-tactic surgery, in which small cuts are made in speci?c brain ?bres under X-ray guidance, has super-seded the more generalised lobotomies of old. The Mental Health Act 1983 ensures that psychosurgery is performed only when the patient has given fully informed consent and a second medical opinion has agreed that it is necessary. For all other psychiatric treatments (except another rare treatment, hormone implantation for reducing the sex drive of sex o?enders), either consent or a second opinion is needed – not both. TREATMENT IN HOSPITAL Psychiatric wards do not look like medical or surgical wards and sta? may not wear uniforms. Patients do not need to be in their beds during the day, so the beds are in separate dormitories. The main part of most wards is a living space with a day room, an activity and television room, quiet rooms, a dining room, and a kitchen. Ward life usually has a certain routine. The day often starts with a community meeting at which patients and nurses discuss issues that affect the whole ward. Patients may go to the occupational therapy department during the day, but there may also be some therapy groups on the ward, such as relaxation training. Patients’ symptoms and problems are assessed continuously during a stay in hospital. When patients seem well enough they are allowed home for trial periods; then discharge can be arranged. Patients are usually followed up in the outpatient clinic at least once.

TREATING PATIENTS WITH ACUTE PSYCHIATRIC ILLNESS Psychiatric emergencies – patients with acute psychiatric illness – may develop from psychological, physical, or practical crises. Any of these crises may need quick professional intervention. Relatives and friends often have to get this urgent help because the sufferer is not ?t enough to do it or, if psychotic, does not recognise the need. First, they should ring the person’s general practitioner. If the general practitioner is not available and help is needed very urgently, relatives or friends should phone the local social-services department and ask for the duty social worker (on 24-hour call). In a dire emergency, the police will know what to do.

Any disturbed adult who threatens his or her own or others’ health and safety and refuses psychiatric help may be moved and detained by law. The Mental Health Act of 1983 authorises emergency assessment and treatment of any person with apparent psychiatric problems that ful?l these criteria.

Although admission to hospital may be the best solution, there are other ways that psychiatric services can respond to emergencies. In some districts there are ‘crisis intervention’ teams of psychiatrists, nurses, and social workers who can visit patients urgently at home (at a GP’s request) and, sometimes, avert unnecessary admission. And research has shown that home treatment for a range of acute psychiatric problems can be e?ective.

LONG-TERM TREATMENT AND COMMUNITY CARE Long-term treatment is often provided by GPs with support and guidance from psychiatric teams. That is ?ne for people whose problems allow them to look after themselves, and for those with plenty of support from family and friends. But some people need much more intensive long-term treatment and many need help with running their daily lives.

Since the 1950s, successive governments have closed the old psychiatric hospitals and have tried to provide as much care as possible outside hospital – in ‘the community’. Community care is e?ective as long as everyone who needs inpatient care, or residential care, can have it. But demand exceeds supply. Research has shown that some homeless people have long-term mental illnesses and have somehow lost touch with psychiatric services. Many more have developed more general long-term health problems, particularly related to alcohol, without ever getting help.

The NHS and Community Care Act 1990, in force since 1993, established a new breed of professionals called care managers to assess people whose long-term illnesses and disabilities make them unable to cope completely independently with life. Care managers are given budgets by local councils to assess people’s needs and to arrange for them tailor-made packages of care, including services like home helps and day centres. But co-ordination between health and social services has sometimes failed – and resources are limited – and the government decided in 1997 to tighten up arrangements and pool community-care budgets.

Since 1992 psychiatrists have had to ensure that people with severe mental illnesses have full programmes of care set up before discharge from hospital, to be overseen by named key workers. And since 1996 psychiatrists have used a new power called Supervised Discharge to ensure that the most vulnerable patients cannot lose touch with mental-health services. There is not, however, any law that allows compulsory treatment in the community.

There is ample evidence that community care can work and that it need not cost more than hospital care. Critics argue, however, that even one tragedy resulting from inadequate care, perhaps a suicide or even a homicide, should reverse the march to community care. And, according to the National Schizophrenia Fellowship, many of the 10–15 homicides a year carried out by people with severe mental illnesses result from inadequate community care.

Further information can be obtained from the Mental Health Act Commission, and from MIND, the National Association for Mental Health. MIND also acts as a campaigning and advice organisation on all aspects of mental health.... mental illness

Monomania

Monomania is a form of MENTAL ILLNESS, in which the affected person has delusion (see DELUSIONS) upon one subject, although he or she can converse rationally and is a responsible individual upon other matters.... monomania

Delusion Of Reference

a *delusion in which the patient believes that unsuspicious occurrences refer to him or her in person. Patients may, for example, believe that certain news bulletins have a direct reference to them, that music played on the radio is played for them, or that car licence plates have a meaning relevant to them. Ideas of reference differ from delusions of reference in that insight is retained.... delusion of reference

Brain Syndrome, Organic

Disorder of consciousness, intellect, or mental functioning that is of organic (physical), as opposed to psychiatric, origin. Causes include degenerative diseases, such as Alzheimer’s disease; infections; certain drugs; or the effects of injury, stroke, or tumour. Symptoms range from mild confusion to stupor or coma. They may also include disorientation, memory loss, hallucinations, and delusions (see delirium). In the chronic form, there is a progressive decline in intellect, memory, and behaviour (see dementia). Treatment is more likely to be successful with the acute form. In chronic cases, irreversible brain damage may already have occurred. (See also psychosis.)... brain syndrome, organic

Dementia

A condition characterised by a deterioration in brain function. Dementia is almost always due to Alzheimer’s disease or to cerebrovascular disease, including strokes. Cerebrovascular dis-ease is often due to narrowed or blocked arteries in the brain. Recurrent loss of blood supply to the brain usually results in deterioration that occurs gradually but in stages. A small proportion of cases of dementia in people younger than 65 have a underlying treatable cause such as head injury, brain tumour, encephalitis, or alcohol dependence.

The main symptoms of dementia are progressive memory loss, disorientation, and confusion. Sudden outbursts or embarrassing behaviour may be the first signs of the condition. Unpleasant personality traits may be magnified; families may have to endure accusations, unreasonable demands, or even assault. Paranoia, depression, and delusions may occur as the disease worsens. Irritability or anxiety gives way to indifference towards all feelings. Personal habits deteriorate, and speech becomes incoherent. Affected people may eventually need total nursing care.

Management of the most common

Alzheimer-type illness is based on the treatment of symptoms. Sedative drugs may be given for restlessness or paranoia. Drugs for dementia, for example donepezil, can slow mental decline in some people with mild to moderate Alzheimer’s disease (see acetylcholinesterase inhibitors).... dementia

Manic–depressive Illness

A mental disorder that is characterized by a disturbance of mood. The disturbance may be unipolar (consisting of either depression or mania) or bipolar (swinging between the two). In a severe form that is sometimes referred to as manic– depressive psychosis, there may also be grandiose ideas or negative delusions.

Abnormalities in brain biochemistry, or in the structure and/or function of certain nerve pathways within the brain, could underlie manic–depressive illness. An inherited tendency is also an established causative factor.Severe manic–depressive illness often needs hospital treatment. Antidepressant drugs and/or ECT are used to treat depression, and antipsychotic drugs are given to control manic symptoms. Carbamazepine or lithium may be used to prevent relapse.

Group therapy, family therapy, and individual psychotherapy may be useful in treatment. Cognitive–behavioural therapy may also be helpful. With treatment, more than 80 per cent of patients improve or remain stable. Even those with severe illness may be restored to near normal health with lithium.... manic–depressive illness

Marijuana

The flowering tops and dried leaves of the Indian hemp plant CANNABIS SATIVA, containing the active ingredient (tetra-hydrocannabinol). The leaves are usually smoked but can be drunk as tea or eaten in food. Physical effects of marijuana include dry mouth, mild reddening of the eyes, slight clumsiness, and an increased appetite. The main subjective feelings are usually of calmness and wellbeing, but depression occurs occasionally.Large doses may cause panic, fear of death, and illusions. In rare cases, true psychosis occurs, with paranoid delusions, confusion, and other symptoms, which usually disappear within a few days. Regular use of marijuana may lead to a more permanent state of apathy and loss of concern (a condition that is known as amotivational syndrome).... marijuana

Postnatal Depression

Depression in a woman after childbirth. The cause is probably a combination of sudden hormonal changes and psychological and environmental factors. The depression ranges from an extremely common and mild, shortlived episode (“baby blues”) to a rare, severe depressive psychosis.

Most mothers first get the “blues” 4–5 days after childbirth and may feel miserable, irritable, and tearful. The cause is hormonal changes, perhaps coupled with a sense of anticlimax or an overwhelming sense of responsibility for the baby. With reassurance and support, the depression usually passes in 2–3 days. In about 10–15 per cent of women, the depression lasts for weeks and causes a constant feeling of tiredness, difficulty in sleeping, loss of appetite, and restlessness. The condition usually clears up of its own accord or is treated with antidepressant drugs.

Depressive psychosis usually starts 2–3 weeks after childbirth, causing severe mental confusion, feelings of worthlessness, threats of suicide or harm to the baby, and sometimes delusions.

Hospital admission, ideally with the baby, and antidepressant drugs are often needed.... postnatal depression

Late-onset Schizophrenia

a mental disorder characterized by systematic *delusions and commonly auditory *hallucinations, but without any other marked symptoms of *mental illness; it was formerly known as paraphrenia. The only loss of contact with reality is in areas affected by the delusions and hallucinations. It is typically seen in the elderly and can also occur in people with severe hearing impediments. Some people develop other symptoms of *schizophrenia over time but in many the personality remains intact over years. *Antipsychotic medication is often useful in treating the illness.... late-onset schizophrenia

Megalomania

n. an obsolete word for delusions of grandeur, such as being God, royalty, etc. It may be a feature of a schizophrenic or manic illness.... megalomania

Positive Symptoms

(in psychiatry) symptoms of schizophrenia characterized by a distortion of some aspect of functioning, such as delusions, hallucinations, or disordered speech. Compare negative symptoms.... positive symptoms

Hallucinogenic

causes visions or delusions.... hallucinogenic

Thought Disorders

Abnormalities in the structure or content of thought, as reflected in a person’s speech, writing, or behaviour. Schizophrenia causes several thought disorders, including loss of logical connections between associations, the invention of new words (see neologisms), thought blocking (sudden interruption in the train of thought), the feeling that thoughts are being inserted into or withdrawn from the mind, and auditory hallucinations.

Incoherent thoughts occur in all types of confusion, including dementia and delirium. Rapidly jumping from one ideato another occurs in hypomania and mania. In depression, thinking becomes slow, there is a lack of association, and a tendency to dwell in great detail on trivial subjects. In obsessive–compulsive disorder, recurrent ideas seem to come into a person’s mind involuntarily. Delusions, which occur in schizophrenia and other psychotic illnesses, may be an expression of distorted thinking.... thought disorders

Alcoholism

n. the syndrome due to physical *dependence on alcohol, such that sudden deprivation may cause withdrawal symptoms – tremor, anxiety, hallucinations, and delusions (see delirium tremens). The risk of alcoholism for an individual depends on genetic and environmental factors. Several years’ heavy drinking is often needed for addiction to develop, with a wide range from 1 to 40 years. Alcoholism impairs intellectual function, physical skills, memory, and judgment. Social skills can also be affected. Heavy consumption of alcohol causes *cardiomyopathy, *peripheral neuropathy, *cirrhosis of the liver, and enteritis. Treatment is usually provided on an out-patient basis, in specialist units for detoxification or medical wards. Unsupervised sudden withdrawal carries a mortality of about 10%, mostly due to seizures. If there are complicating psychiatric problems detoxification may be part of psychiatric treatment. Psychological aspects of treatment include helping the patient to understand the psychological pressures that led to his or her heavy drinking, treatment of underlying anxiety, and *motivational interviewing. Drugs such as *disulfiram (Antabuse), which cause vomiting if alcohol is taken, can help in treatment. Drugs to reduce craving, such as *acamprosate calcium, are less successful, with around a third of patients benefiting.... alcoholism

Schneiderian First- And Second-rank Symptoms

symptoms of *schizophrenia first classified by German psychiatrist Kurt Schneider (1887–1967) in 1938. First-rank symptoms were considered by Schneider to be particularly indicative of schizophrenia; they include all forms of *thought alienation, *delusional perception, *passivity, and third-person auditory *hallucinations in the form of either a running commentary or voices talking about the patient among themselves. Some schizophrenic patients never exhibit first-rank symptoms or only experience them in some psychotic episodes. They may also occur in *mania. Second-rank symptoms are common symptoms of schizophrenia but also often occur in other forms of mental illness. They include *delusions of reference, paranoid and persecutory *delusions, and second-person auditory hallucinations.... schneiderian first- and second-rank symptoms



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