Denaturation Health Dictionary

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Denaturation: From 1 Different Sources

n. the changes in the physical and physiological properties of a protein that are brought about by heat, X-rays, or chemicals. These changes include loss of activity (in the case of enzymes) and loss (or alteration) of antigenicity (in the case of *antigens).
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Lathyrus Sativus

Linn.

Family: Papilionaceae; Fabaceae.

Habitat: Cultivated chiefly in Madhya Pradesh, Eastern Uttar Pradesh, West Bengal, Andhra Pradesh and Gujarat.

English: Chickling Vetch, Grass Pea.

Folk: Khesaari, Latari, Kalaaya.

Action: Seeds—toxic. Prolonged consumption results in paralysis of legs, both in animals and human beings, known as lathyrism. The toxic substance responsible for lathyrism had been identified as selenium. Peritoneal injection of beta-N-oxalylaminoalanine (isolated from the seeds) produced acute neurolathyrism at LD50 doses (748.8 mg/kg) in mice and (694.9 mg/kg) in chicken; liver and kidney cells showed denaturation, vacuolar and fatty degeneration. (It is a neuropoison, which mainly affects central nervous system.)

Related species include, Lathyrus aphaca Linn., L. sphaericus Retz. and L. tingitanus Linn., known as Kalaaya or Khesaari.... lathyrus sativus

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