Desquamation Health Dictionary

The use of naturally occurring isotopes, or arti?cially produced X-rays, in the killing of tumour cells. The amount of radiation is the adsorbed dose; the SI unit is the gray (Gy).

Di?erent tumours seem to be particularly sensitive to radiation; radiotherapy plays an important role in the management of germ-cell tumours (SEMINOMA; TERATOMA) and lymphomas (see LYMPHOMA). Many head and neck tumours, gynaecological cancers, and localised prostate and bladder cancers are curable with radiotherapy. It may be used to reduce the pain

– for example, from bone metastases.

Unwanted effects Generalised: lethargy, loss of appetite. Skin: ERYTHEMA, dry desquamation with itching, moist desquamation. Patients should keep the treated area(s) dry and clean and avoid soap, antiseptic mouthwashes, smoking and spicy food if possible. (See ISOTOPE; RADIATION SICKNESS; RADIOTHERAPY).... irradiation

A skin disorder typi?ed by a bran-like desquamation (?aking). There are several varieties including P. alba, rosea, versicolor (fungal caused) and rubra (exfoliative dermatitis).

Pityriasis alba is a mild form of chronic eczema (see DERMATITIS) occurring mainly in children on the face and in young adults on the upper arms. It is characterised by round or oval ?aky patches which are paler than the surrounding skin due to partial loss of MELANIN pigment. The appearance is more dramatic in dark-skinned or suntanned subjects. Moisturising cream often su?ces, but 1 per cent HYDROCORTISONE cream is more e?ective.

Pityriasis rosea is a common self-limiting eruption seen mainly in young adults. It usually begins as a solitary red ?aky patch (often misdiagnosed as ringworm). Within a week this ‘herald patch’ is followed by a profuse symmetrical eruption of smaller rose-pink, ?aky, oval lesions on the trunk and neck but largely sparing the limbs and face. Itching is variable. The eruption usually peaks within 3 weeks and fades away leaving collarettes of scale, disappearing within 6–7 weeks. It rarely recurs and a viral cause is suspected but not proved. It is not contagious and there is no speci?c treatment, but crotamiton cream (Eurax) may relieve discomfort.... pityriasis

This disorder is caused by the erythrogenic toxin of the STREPTOCOCCUS. The symptoms of PYREXIA, headache, vomiting and a punctate erythematous rash (see ERYTHEMA) follow a streptococcal infection of the throat or even a wound. The rash is symmetrical and does not itch. The skin subsequently peels.

Symptoms The period of incubation (i.e. the time elapsing between the reception of infection and the development of symptoms) varies somewhat. In most cases it lasts only two to three days, but in occasional cases the patient may take a week to develop his or her ?rst symptoms. The occurrence of fever is usually short and sharp, with rapid rise of temperature to 40 °C (104 °F), shivering, vomiting, headache, sore throat and marked increase in the rate of the pulse. In young children, CONVULSIONS or DELIRIUM may precede the fever. The rash usually appears within 24 hours of the onset of fever and lasts about a week.

Complications The most common and serious of these is glomerulonephritis (see under KIDNEYS, DISEASES OF), which may arise during any period in the course of the fever, but particularly when DESQUAMATION occurs. Occasionally the patient develops chronic glomerulonephritis. Another complication is infection of the middle ear (otitis media – see under EAR, DISEASES OF). Other disorders affecting the heart and lungs occasionally arise in connection with scarlet fever, the chief of these being ENDOCARDITIS, which may lay the foundation of valvular disease of the heart later in life. ARTHRITIS may produce swelling and pain in the smaller rather than in the larger joints; this complication usually occurs in the second week of illness. Scarlet fever, which is now a mild disease in most patients, should be treated with PENICILLIN.... scarlet fever

 Erythroderma. Redness and thickening of the skin which later peels off in layers (desquamation). Follows some chronic skin disorders: leukaemia, Hodgkin’s disease or fungoid invasion. May involve the whole of the body.

Alternatives. Teas. Betony, Burdock leaves, Bogbean, Chickweed, Clivers, Dandelion, Gotu Kola, Ground Ivy, Figwort, Red Clover, Violet, Yarrow.

Cold tea. Barberry bark: one heaped teaspoon to each teacup cold water; stand overnight, drink 1 cup morning and evening next day (most effective).

Tablets/capsules. Blue Flag root, Burdock, Devil’s Claw, Echinacea, Garlic, Poke root, Queen’s Delight, Red Clover, Seaweed and Sarsaparilla.

Formula. Equal parts: Dandelion, Echinacea, Yellow Dock root. Dose – Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: one 5ml teaspoon. Tinctures: two 5ml teaspoons. Thrice daily before meals.

Topical. Alternatives to corticosteroids. Tamus tincture or salve – see Black Bryony. Aloe Vera, Witch Hazel, Comfrey, Evening Primrose, Jojoba, Thuja. Bran bath.

Diet. See: DIET – SKIN DISEASES. ... dermatitis, exfoliative

n. the act of shedding skin; *desquamation.... ecdysis

(hand–foot syndrome) a skin reaction marked by redness, numbness, and desquamation of the palms of the hands and soles of the feet. It can be caused by many chemotherapy drugs, particularly fluorouracil and capecitabine, and tyrosine kinase inhibitors. Treatment requires cessation of the drug.... palmoplantar erythrodysaesthesia