Habitat: Native to eastern United States; imported into India.
English: Indian Tabacco, Pukeweed.Ayurvedic: Devanala (var.).
Action: Antiasthmatic, antispasmodic, broncho-dilator, expectorant, mild sedative and relaxant. Used as a tabacco deterrent (as a major ingredient in many antismoking mixtures).
Key application: In the treatment of asthma, bronchitis. (German Commission E.) As respiratory stimulant. (The British Herbal Pharmacopoeia.)Lobelia contains piperidine alkaloids, mainly lobeline, with lobelanine, lobelanidine, norlobelanine, isolobi- nine. Lobeline stimulates respiration in animals by stimulating respiratory centre and at high doses stimulates the vomiting centre.Lobeline has similar but less potent pharmacological properties to nicotine but 1/20-1/5 as potent.Lobeline (0.5%) has also been used as an active ingredient in skin-lightening preparations.Clinical research could not demonstrate lobeline efficacy greater than placebo in smoking cessation. It was disallowed as an ingredient in antismoking products in the US in 1993. (Natural Medicines Comprehensive Database, 2007.)The leaves contain beta-amyrin pal- mitate which possesses sedative and antidepressant properties comparable to the antidepressant drug mianserin. Methanolic extract of leaves exhibited antidepressant activity.The leaf powder is toxic at 0.6-1.0 , (Francis Brinker.)... lobelia inflata
Action: Leaves—filtered solution is used in the control of aphids, tingids and mites on vegetable and other crops. Plant—poisonous to man and livestock. The leaves are cured and smoked as tabacco.... lobelia leschenaultina
An analysis of Lobelia nicotianae- folia, grown in Maharashtra, shows that the plant contains appreciable quantities of nor-lobelanine and small amounts of lobinine and minor bases.Lobelia cardinalis Linn., Cardinal Flower, is cultivated in Indian gardens. It contains lobinaline as main alkaloid. Lobinaline depresses blood pressure but has no influence on respiration. L. erinus Linn. and L. succulenta Blume, synonym L. affinis Wall. also contain alkaloids with lobinaline 0.445%.Lobelia cordigera Cav., synonym L. fulgens Willd., an ornamental Lobelia sp., grown in Indian gardens, contains inulin.Lobelia pyramidalis Wall. (Himalayas from Kumaon eastwards to Sikkim and Assam at altitudes of900-2,700 m) contains 0.29-0.38% alkaloids as lobeline, and may be used as a substitute for Lobelia inflata.... lobelia nicotianaefolia
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