Direct Oral Anticoagulant: From 1 Different Sources
(DOAC) a relatively recently introduced class of drugs that reduce coagulation of the blood by inhibition of one of the coagulation factors (Factor Xa). They may be used as an alternative to *warfarin in many (but not all) cases, their advantage being that regular blood tests are not required for dose adjustment. Examples include, apixaban, dabigatran, edoxaban, and rivaroxaban.
Relating to the mouth. The area with the mouth opening.... oral
Inhibiting the clotting of blood ... anticoagulant
A contraceptive taken by mouth (see CONTRACEPTION). It comprises one or more synthetic female hormones, usually an oestrogen (see OESTROGENS), which blocks normal OVULATION, and a progestogen which in?uences the PITUITARY GLAND and thus blocks normal control of the woman’s menstrual cycle (see MENSTRUATION). Progestogens also make the uterus less congenial for the fertilisation of an ovum by the sperm.... oral contraceptive
A branch of surgery that treats deformities, injuries or diseases of the TEETH and JAW, as well as other areas of the face and mouth. Surgeons doing this work are usually quali?ed dentists who have done further training in oral and maxillofacial surgery.... oral surgery
See rehydration therapy.... oral rehydration therapy
See “cost”.... direct cost
Any activities by a health professional involving direct interaction, treatment, administration of medications or other therapy or involvement with a patient.... direct patient care
Perform surgery to the mouth and face. This not only includes removal of buried teeth but also treatment for fractured facial bones, removal of cancers and the repair of missing tissue, and the cosmetic restoration of facial anomalies such as CLEFT PALATE or large or small jaws.... oral and maxillo-facial surgeons
The optimal state of the mouth and normal functioning of the organs of the mouth without evidence of disease.... oral health
Giving a remedy by mouth. Such a route leads to its passage through the mucous membrane lining the intestines and from there into the bloodstream. ... oral administration
See oral hygiene.... hygiene, oral
A group of oral drug preparations containing one or more synthetic female sex hormones, taken by women in a monthly cycle to prevent pregnancy. “The pill” commonly refers to the combined or the phased pill, which both contain an oestrogen drug and a progestogen drug, and the minipill, which contains only a progestogen. Oestrogen pills include ethinylestradiol; progestogens include levonorgestrel and norethisterone. When used correctly, the number of pregnancies among women using oral contraceptives for one year is less than 1 per cent. Actual failure rates may be 4 times higher, particularly for the minipill, which has to be taken at precisely the same time each day.
Combined and phased pills increase oestrogen and progesterone levels. This interferes with the production of two hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation. The minipill works mainly by making the mucus lining of the cervix too thick to be penetrated by sperm.
Oestrogen-containing pills offer protection against uterine and ovarian cancer, ovarian cysts, endometriosis, and irondeficiency anaemia. They also tend to make menstrual periods regular, lighter, and relatively pain-free. Possible side effects include nausea, weight gain, depression, swollen breasts, reduced sex drive, increased appetite, leg and abdominal cramps, headaches, and dizziness. More seriously, there is a risk of thrombosis causing a stroke or a pulmonary embolism. These pills may also aggravate heart disease or cause hypertension, gallstones, jaundice, and, very rarely, liver cancer. All oral contraceptives can cause bleeding between periods, especially the minipill. Other possible adverse effects of the minipill include irregular periods, ectopic pregnancy, and ovarian cysts. There may be a slightly increased long-term risk of breast cancer for women taking the combined pill.
Oestrogen-based pills should generally be avoided in women with hypertension, hyperlipidaemia, liver disease, migraine, otosclerosis, or who are at increased risk of a thrombosis. They are not usually prescribed to a woman with a personal or family history of heart or circulatory disorders, or who suffers from unexplained vaginal bleeding. The minipill or a lowoestrogen pill may be used by women who should avoid oestrogens. Combined or phased pills may interfere with milk production and should not be taken during breast-feeding. Certain drugs may impair the effectiveness of oral contraceptives. (See also contraception.) ... oral contraceptives
See rehydration therapy.... rehydration, oral
one of several autoantibodies that can cause *antiphospholipid antibody syndrome (APS). Despite the name, the antibody behaves as a coagulant, increasing the risk of thrombosis. It can be found in 50% of patients with APS.... lupus anticoagulant
the mouth.... oral cavity
(oral antihyperglycaemic drug) one of the group of drugs that reduce the level of glucose in the blood and are taken by mouth for the treatment of type 2 *diabetes mellitus. They include the *sulphonylurea group (e.g. glibenclamide, gliclazide), metformin (a *biguanide), *alpha-glucosidase inhibitors, *meglitinides, *thiazolidinediones, *DPP-IV inhibitors, and *SGLT-2 inhibitors.... oral hypoglycaemic drug
see stomatology.... oral medicine
the procedure of rebuilding a dentition that has been mutilated as a result of disease, wear, or trauma.... oral rehabilitation
(TORS) a form of robot-assisted surgery used for treating difficult-to-access tumours of the pharynx and larynx.... trans-oral robotic surgery
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