(DOAC) a relatively recently introduced class of drugs that reduce coagulation of the blood by inhibition of one of the coagulation factors (Factor Xa). They may be used as an alternative to *warfarin in many (but not all) cases, their advantage being that regular blood tests are not required for dose adjustment. Examples include, apixaban, dabigatran, edoxaban, and rivaroxaban.... direct oral anticoagulant