Drug Therapy: From 1 Different Sources
The use of drugs to treat a medical problem, to improve a person’s condition or to otherwise produce a therapeutic effect.
Therapy designed to help individuals improve their independence in daily living activities through rehabilitation, exercises and the use of assistive devices. In addition, such therapy provides activities to promote growth, self-fulfilment and self-esteem.... occupational therapy
A form of psychiatric treatment based on learning theory. Symptoms are considered to be conditioned responses, and treatment is aimed at removing them, regardless of the underlying diagnosis. Desensitisation, operant conditioning, and aversion therapy are examples of behaviour therapy. (See MENTAL ILLNESS.)... behaviour therapy
An agent that is used therapeutically to treat diseases. It may also be defined as any chemical agent and/or biological product or natural product that affects living processes... drug
Psychotherapy in which at least two, but more commonly up to ten, patients, as well as the therapist, take part. The therapist encourages the patients to analyse their own and the others’ emotional and psychological diffculties. Group therapy is also used to help patients sharing the same condition – for instance, alcoholism or compulsive gambling. They discuss their problems for perhaps an hour twice a week and explore ways of resolving them.... group therapy
The treatment of speech and communication disorders.... speech therapy
One third of those taking tranquillisers become addicted. One of the problems of psychological dependence is the discomfort of withdrawal symptoms.
Symptoms. Tremors, restlessness, nausea and sleep disturbance. The greater potency of the drug, the higher the rebound anxiety. Many drugs create stress, weaken resistance to disease, tax the heart and raise blood sugar levels.
Drugs like Cortisone cause bone loss by imperfect absorption of calcium. Taken in the form of milk and dairy products, calcium is not always absorbed. Herbs to make good calcium loss are: Horsetail, Chickweed, Slippery Elm, Spinach, Alfalfa.
Agents to calm nerves and promote withdrawal may augment a doctor’s prescription for reduction of drug dosage, until the latter may be discontinued. Skullcap and Valerian offer a good base for a prescription adjusted to meet individual requirements.
Alternatives. Teas: German Chamomile, Gotu Kola, Hops, Lime flowers, Hyssop, Alfalfa, Passion flower, Valerian, Mistletoe, Oats, Lavender, Vervain, Motherwort. 1 heaped teaspoon to each cup boiling water; infuse 5-15 minutes; half-1 cup thrice daily.
Decoctions: Valerian, Devil’s Claw, Siberian Ginseng, Lady’s Slipper. Jamaica Dogwood, Black Cohosh.
Tablets/capsules. Motherwort, Dogwood, Valerian, Skullcap, Passion flower, Mistletoe, Liquorice. Powders. Formulae. Alternatives. (1) Combine equal parts Valerian, Skullcap, Mistletoe. Or, (2) Combine Valerian 1; Skullcap 2; Asafoetida quarter. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily. Formula No 2 is very effective but offensive to taste and smell.
Practitioner. Tincture Nucis vom. once or twice daily, as advised.
Aloe Vera gel (or juice). Russians tested this plant on rabbits given heavy drug doses and expected to die. Their survival revealed the protective property of this plant: dose, 1 tablespoon morning and evening. Aromatherapy. Sniff Ylang Ylang oil. Lavender oil massage for its relaxing and stress-reducing properties.
Diet. Avoid high blood sugar levels by rejecting alcohol, white flour products, chocolate, sugar, sweets and high cholesterol foods.
Supplements. Daily. Multivitamins, Vitamin B-complex, B6, Vitamin C 2g, Minerals: Magnesium, Manganese, Iron, Zinc. Change of lifestyle. Stop smoking. Yoga.
Notes. “Do not withdraw: insulin, anticoagulants, epileptic drugs, steroids, thyroxin and hormone replacement therapy (the endocrine glands may no longer be active). Long-term tranquillisers e.g., Largactil or any medicament which has been used for a long period. Patients on these drugs are on a finely-tuned medication the balance of which may be easily disturbed.” (Simon Mills, FNIMH)
Counselling and relaxation therapy.
The Committee on Safety of Medicines specifically warns against the abrupt cessation of the Benzodiazepines and similar tranquillisers because of the considerable risk of convulsions. ... drug dependence
Within a few years medical scientists have introduced into the domestic scene a steroid which has changed the whole course of female history. HRT has solved some basic medical problems by making good the loss of oestrogen in a woman’s body when menstruation is finished and her body learns to adjust.
A lack of oestrogen induces hot flushes, night sweats, thinning of the bones (osteoporosis) with possible fractures, and a wide range of physical and emotional disorders.
HRT also prevents the increased frequency of coronary disease which may follow the menopause. With oestrogen only, HRT appears to increase the incidence of cancer of the uterine body. Use of oestrogen and progestogen avoids this.
HRT is available as a tablet, transdermal patch, implant or topical cream. Most women notice temporary improvement in their appearance and hot flushes as long as treatment is continued. HRT is not prescribed by the herbal practitioner. Soya and Hops are a mild alternative.
Side-effects of such treatment include blood pressure rise, weight gain and periods probably continue with a monthly bleed. Elderly women taking HRT for osteoporosis may develop bleeding problems, the risk of blood clot and gall bladder diseases.
Helonias has proved a useful alternative, effective in eliminating excess fluids, reducing hot flushes, and relieving that bloated feeling, thus helping the older woman to live a normal life.
Damiana. 1 heaped teaspoon leaves to each cup boiling water; infuse 5-10 minutes; strain. 1 cup 2-3 times daily for 3-6 weeks.
Sarsaparilla. 1oz (30g) root in 1 pint (500ml) water; simmer gently 20 minutes; strain. 1 cup 2-3 times daily for 3-6 weeks.
Supplementation. Daily. Vitamin E, 400iu. Vitamin B-complex (high potency). Evening Primrose oil capsules, 500mg morning and evening. Dolomite, for Calcium and Magnesium, 2 tablets morning and evening.
Note: An extensive study of breast cancer risks with HRT revealed a positive link between the risk of cancer and length of use. Risk of the disease increased with all types of women using HRT with every year of use. Pre-menstrual women were more than twice at risk. It would appear that oestrogens cannot be taken without risk. (Centre for Disease Control, Atlanta, USA) See: OESTROGENS. ... hormone replacement therapy (hrt)
A form of psychological treatment in which such an unpleasant response is induced to his or her psychological aberration that the patient decides to give it up. Thus the victim of alcoholism is given a drug that makes the subsequent drinking of alcoholic liquors so unpleasant, by inducing nausea and vomiting, that he or she decides to give up drinking. (See ALCOHOL; DISULFIRAM.) Aversion therapy may help in the treatment of alcoholism, drug addiction, sexual deviations such as transvestism, and compulsive gambling.... aversion therapy
See DEPENDENCE.... drug addiction
A medicinal drug that is sold under its o?cial (generic) name instead of its proprietary (patented brand) name. NHS doctors are advised to prescribe generic drugs where possible as this enables any suitable drug to be dispensed, saving delay to the patient and sometimes expense to the NHS. (See APPROVED NAMES FOR MEDICINES.)... generic drug
This comprises a photosensitising agent (one activated by light), which accumulates in malignant tissue, and a source of light that activates the photosensitiser, triggering it to generate highly reactive oxygen compounds that destroy malignant cells. One such photosensitiser is temopor?n. Photodynamic therapy is used to treat various types of malignancy; a recognised complication is photosensitivity, when a patient may suffer burns after transient exposure to sunlight. Photodynamic therapy is increasingly used and photosensitivity reactions may also become more common.... photodynamic therapy
This is a treatment in which patients are helped to reduce their levels of anxiety by reducing their muscle tone. It can be used on its own or in conjunction with a broader PSYCHOTHERAPY regime. The technique guides people on how to cope with stressful situations and deal with phobias – see PHOBIA.... relaxation therapy
The counselling and treatment of individuals with psychosexual dysfunction (see SEXUAL DYSFUNCTION). Around half of couples experience some type of sexual problem during their relationships, and for most of them the diffculties are psychological. Sexual therapy is usually given to both partners, but sometimes individual counselling is necessary. Couples may sometimes ?nd that group therapy is helpful. Therapy has proved e?ective especially for women with VAGINISMUS (spasm of vaginal muscles), men with PREMATURE EJACULATION or IMPOTENCE, and men and women who fail to achieve ORGASM.... sex therapy
See ELECTROCONVULSIVE THERAPY (ECT).... shock therapy
The treatment of injury or disease.... therapy
A drug that increases the amount of URIC ACID excreted in the URINE. Among the drugs used are PROBENECID or a sulfa derivative. Uricosurics are used to treat GOUT and other disorders which cause raised blood-uric-acid concentrations.... uricosuric drug
See ECT.... electroconvulsive therapy
A form of psychotherapy that aims to promote greater harmony and understanding between members of a family, most often between parents and adolescent children.... family therapy
See rehydration therapy.... oral rehydration therapy
See over-the-counter drug.... otc drug
The application of computer technology to therapy.... computer-assisted therapy
A dried, unprocessed plant, and referring to one that was or is an official drug plant or the source of a refined drug substance. A—... crude drug
See “day care centre”.... day therapy centre
Drugs are usually administered distant to their site of action in the body; they must then pass across cell membranes to reach their site of action. For example, drugs given by mouth must pass across the gut membrane to enter the bloodstream and then pass through the endothelium of vessel walls to reach the site of action in the tissues. This process is called absorption and may depend on lipid di?usion, aqueous di?usion, active transport, or pinocytosis – a process in which a cell takes in small droplets of ?uid by cytoplasmic engulfment.... drug absorption
Also known as ‘date rape’, this is an unwelcome phenomenon in which an intending rapist undermines a potential victim’s resistance by giving her a hypnotic drug such as benzodiazepine. The British National Formulary warns that ?unitrazepam (Rohypnol®) tablets may be particularly subject to abuse – perhaps given to the unsuspecting victim in an alcoholic drink so the sedative e?ect is greatly enhanced.... drug assisted rape
The process of attachment of a drug to a receptor or plasma protein, fat, mucopolysaccharide or other tissue component. This process may be reversible or irreversible.... drug binding
The volume of blood from which a drug is completely removed in one minute is known as clearance. Renal clearance of a drug is the amount of blood completely cleared of the drug by the kidney in one minute.... drug clearance
A process by which the body destroys and excretes drugs, so limiting their duration of action. Phase 1 metabolism consists of transformation by oxidation, reduction, or hydrolysis. In phase 2 this transformed product is conjugated (joined up) with another molecule to produce a water-soluble product which is easier to excrete.... drug metabolism
A finished dosage form, for eg., a tablet, capsule or solution that contains a drug substance... drug product
An active ingredient that is intended to furnish pharmacological activity or other direct effect in diagnosis, cure, mitigation, treatment or prevention of diseases or to effect the structure or any function of the human body... drug substance
A formal programme for assessing drug prescription and use patterns. DURs typically examine patterns of drug misuse, monitor current therapies, and intervene when prescription or utilization patterns fall outside pre-established standards. DUR is usually retrospective, but can also be performed before drugs are dispensed.... drug utilization review (dur)
Generic drugs have been licensed as equivalent to brand name drugs. Generics are usually less expensive and they may be substituted by the dispenser.... generic drug substitution
See under MENOPAUSE.... hormone replacement therapy(hrt)
Sometimes called an intensive care unit, this is a hospital unit in which seriously ill patients undergo resuscitation, monitoring and treatment. The units are sta?ed by doctors and nurses trained in INTENSIVE CARE MEDICINE, and patients receive 24-hour, one-to-one care with continuous monitoring of their condition with highly specialised electronic equipment that assesses vital body functions such as heart rate, respiration, blood pressure, temperature and blood chemistry. The average ITU in Britain has four to six beds, although units in larger hospitals, especially those dealing with tertiary-care referrals – for example, neurosurgical or organ transplant cases – are bigger, but 15 beds is usually the maximum. Annual throughput of patients ranges from fewer than 200 to more than 1,500 patients a year. As well as general ITUs, specialty units are provided for neonatal, paediatric, cardiothoracic and neurological patients in regional centres. The UK has 1–2 per cent of its hospital beds allocated to intensive care, a ?gure far below the average of 20 per cent provided in the United States. Thus patients undergoing intensive care in the UK are usually more seriously ill than those in the US. This is re?ected in the shortage of available ITU beds in Britain, especially in the winter. (See CORONARY CARE UNIT (CCU); HIGH DEPENDENCY UNIT.)... intensive therapy unit (itu)
Green tea is considered a “wonder drug” because of its healthy contribution in human diets. Its antioxidant properties fight successfully against cancer, but not only.
Green tea description
Green tea is made from Camellia sinensis, an Asian plant, originating from China, Japan and South Korea. Oolong tea and black tea are prepared from the same plant as the green tea. A special feature of this type of tea is the ability to block the natural process of fermentation: after being picked, its leaves are steamed, dried and then rolled, thus blocking fermentation.
Due to its constituents, it acts as an antioxidant, diuretic, cerebral and fattening burning stimulator, and also as a cancer protector.
Green tea has been the subject of many scientific and medical studies so as to determine its health benefits. It seems that regular green tea drinkers may have a lower risk of developing heart diseases and certain types of cancer.
There are several types of green tea available on the market: Bancha Tea,
Chun Hao Tea ,
Dao Ren Tea ,
Dragonwell Tea ,
Genmaicha Tea ,
Gunpowder ,
Gyokuro Tea ,
Hojicha Tea , Kai Hua Long Ding Tea,
Kukicha Tea ,
Matcha Tea ,
Sencha Tea , White Monkey Tea.
Green Tea brewing
To prepare
green tea, use
: two grams of tea per 100ml of water, or one teaspoon of green tea per five ounce cup.
Green tea steeping time varies from thirty seconds to two, three minutes. The temperature differs as well, from 140°F to 190°F.
Consumers recommend that lower-quality green teas to be steeped hotter and longer and higher-quality teas to be steeped cooler and shorter. In case of steeping the green tea too hot or too long, the resulting beverage is bitter and astringent.
Green Tea benefits
Green Tea lowers the risk of cancer.
Studies have shown the green tea’s contribution against tumors growth, due to its high content of antioxidants, able to fight free radicals which are responsible for cancer spreading.
Green Tea lowers the risk of stroke and heart diseases.
The formation of blood clots (or
thrombosis) is the main cause of the heart attacks and strokes. Green Tea has been acknowledged to exhibit abnormal blood clot formation.
Green Tea lowers blood pressure.
Green Tea is proven to block the effects of an enzyme secreted by the kidneys, considered to be one of the main causes of hypertension.
Green Tea prevents tooth decay.
Dental plaque and bacterial colonies that occur on the tooth surfaces and cause tooth decay can be inhibited by one of the compounds of the
green tea. Also, this beverage has been shown to be effective against fighting gum diseases.
Green Tea inhibits viruses
Studies revealed that
green tea can kill certain bacteria and staphs. It blocks the development of several viruses such as viral hepatitis.
Green tea has also been successful in:
- Slowing early aging;
- Diets;
- The treatment of physical or intellectual fatigue;
- Treating fast cold and flu recovery;
- Preventing allergenic reactions;
- Balancing body fluids;
- Improving the immune function of the epidermis;
- Preventing and mending arthritis;
- Improving bone structure
Green Tea side effects
Green tea is not recommended to patients suffering from high blood pressure, gastric acid secretion, gastritis and ulcer.
Due to the amount of caffeine contained, scientists advise a reduced consumption of green tea for pregnant and nursing women.
Also, this tea should not be drunk after 5 p.m., because the consumption may lead to insomnia, palpitations and agitation.
Green tea is a well known beverage, especially due to its medicinal contribution to a large array of diseases such as arthritis, heart diseases and several types of cancer.... green tea or the wonder drug
1 Treatment of pain, disease or injury by physical means. 2 The profession concerned with promotion of health; prevention of physical disabilities; evaluation and rehabilitation of persons disabled by pain, disease or injury; and with treatment by physical therapeutic measures, as opposed to medical, surgical or radiologic measures.... physical therapy / physiotherapy
Treatment which aims to stimulate older people’s memories by means of old films, pictures, objects, music etc. It allows an older person to remember his or her life’s achievements and contribution and can enhance self-esteem.... reminiscence therapy
The diagnostic evaluation, management and treatment of the care of older persons with deficiencies and abnormalities of the cardiopulmonary (heart lung) system.... respiratory therapy
See IMMUNOLOGY.... serum therapy
A method of treating psychological disorders such as depression based on the idea that problems arise from a person’s faulty cognitions (erroneous ways of perceiving the world and oneself). In cognitive– behavioural therapy, the patient is helped to identify negative or false cognitions and then encouraged to try out new thought strategies.... cognitive–behavioural therapy
GERSON CANCER THERAPY is described in A Cancer Therapy; Results of Fifty Cases, Gerson, Max; 3rd edition, 1977, Pub: The Gerson Institute Bonita, CA 92002, USA.
Basically, the therapy consists of a vegetarian diet with meals of vegetables, fruits and whole grains, fresh or freshly prepared. Drinking water is replaced by hourly, fresh, raw juices of vegetables and fruits. Refined, altered, denatured or enhanced foodstuffs are forbidden. The diet is sodium, chloride, fat and protein restricted. Supplemental potassium, iodine, thyroid and crude liver extract comprise the medical armamentarium. A repeatable choleretic, enemas of a solution of boiled coffee, is administered to lower serum toxin levels. Coffee is a potent enhancer of the carcinogen detoxifying enzyme system, glutathione S-translerase (Wattenburg). The Gerson cancer therapy reduces accumulated tissue sodium and chloride, promoting diuresis. Gerson Therapy Center: Hospital de Baja California, at La Gloria, Mexico
Diet. Lunch and dinner contain ample cooked food, mainly to act as a ‘blotter’ to the daily intake of 5.25 pints fresh raw fruit juices that are the backbone of the therapy. Ingredients of the juices include 41bs raw organic carrots a day, with no harm to the liver. (JAM, May 1991, p5. Beata Bishop on her recovery from metastasised malignant melanoma)
The Gerson therapy is based on the ‘holistic’ philosophy which states that cancer represents a clinical manifestation of an underlying toxic condition. Such condition should receive primary treatment that is lifestyle orientated. The theme is: detoxification through internal cleansing. The diet and supplements are re-inforced by ‘positive thinking’ and supported by meditation and emotional balance. ... gerson cancer therapy
A preparation containing more than one active substance.... combination drug
The effect of a drug when it is taken in combination with other drugs or with substances such as alcohol.... drug interaction
The taking of an excessive amount of a drug, which may cause toxic effects (see drug poisoning).... drug overdose
A method used in the psychoanalysis of young children, based on the principle that all play has some symbolic significance. Watching a child at play helps a therapist diagnose the source of the child’s problems; the child can then be helped to “act out” thoughts and feelings that are causing anxiety.... play therapy
treatment given to patients after the primary therapy, which is usually surgical removal of the tumour, when there is a high risk of future recurrence based on tumour stage and histology. Adjuvant therapy is aimed at destroying these microscopic tumour cells either locally (e.g. adjuvant breast irradiation after breast-conserving surgery) or systemically (e.g. adjuvant chemotherapy may be recommended for patients with breast cancer, colorectal cancer, and other types of cancer). Compare neoadjuvant chemotherapy.... adjuvant therapy
see anticonvulsant.... antiepileptic drug
any one of a class of drugs that reduce platelet aggregation (see platelet activation) and therefore the formation of clot (see thrombosis). Examples are *abciximab, *aspirin, *clopidogrel, prasugrel, and ticagrelor.... antiplatelet drug
(ARV) any of a group of drugs that inhibit or slow the growth of *retroviruses, specifically HIV, and are used in the treatment of HIV infection and *AIDS. They include the *reverse transcriptase inhibitors and the *protease inhibitors (see also maraviroc; raltegravir). Treatment with a combination of antiretrovirals is known as highly active antiretroviral therapy (HAART).... antiretroviral drug
any drug that reduces the normal rate of secretion of a body fluid, usually one that reduces acid secretion into the stomach. Such drugs include *antimuscarinic drugs, H2-receptor antagonists (see antihistamine), and *proton-pump inhibitors.... antisecretory drug
a drug effective against viruses that cause disease. Antiviral drugs include *DNA polymerase inhibitors (e.g. *aciclovir, *foscarnet, *ganciclovir), *ribavirin, and *oseltamivir; they are used for treating herpes, cytomegalovirus and respiratory syncytial virus infections, and influenza. Antiviral drugs are also used for treating HIV infection and AIDS (see antiretroviral drug).... antiviral drug
(AVT) a technique for teaching deaf children to communicate that focuses on speech and residual hearing rather than sign language.... auditory verbal therapy
any treatment that facilitates the ability of the immune system to fight disease, as opposed to acting directly against the disease (compare chemotherapy; radiotherapy). Such treatments, most commonly used for cancer and rheumatic disease, include *biological response modifiers, *immunotherapy, *monoclonal antibodies, *cytokine inhibitors and modulators, and *targeted agents.... biological therapy
(CRT) a treatment for heart failure that involves ventricular pacing with multiple *leads. The aim is to restore coordinated ventricular contraction and hence improve cardiac function.... cardiac resynchronization therapy
(Rogerian therapy) a method of psychotherapy in which the therapist refrains from directing clients in what they should do and instead concentrates on communicating understanding and acceptance. Frequently the therapist reflects the clients’ own words or feelings back to them. The aim is to enable clients to solve their own problems.... client-centred therapy
(CBT) a *cognitive therapy that is combined with behavioural elements (see behaviour therapy). The patient is encouraged to analyse his or her specific ways of thinking around a problem. The therapist then looks at the resulting behaviour and the consequences of that thinking and tries to encourage the patient to change his or her cognition in order to avoid adverse behaviour or its consequences. CBT is successfully used to treat phobias, anxiety, and depression (it is among the recommended treatments for anxiety and depression in the NICE guidelines).... cognitive behavioural therapy
a form of *psychotherapy based on the belief that psychological problems are the products of faulty ways of thinking about the world. For example, a depressed patient may use wrongly negative automatic associations in everyday situations. The therapist assists the patient to identify these false ways of thinking and to avoid them. In *cognitive behavioural therapy this is combined with an analysis and retraining of unhelpful behaviours. In cognitive analytical therapy (CAT) there is an element of psychodynamic exploration of the patient’s problems; CAT is mostly used to treat personality disorders.... cognitive therapy
therapy that combines several types of treatment in order to improve results. It is usually a combination of surgery with radiotherapy and/or chemotherapy for the treatment of malignant tumours (see adjuvant therapy). See also sandwich therapy.... combined therapy
a form of *radiotherapy in which a radioactive substance is brought into close contact with the part of the body being treated. Needles or capsules of the isotope may be implanted in or around a tumour so that the radiation they emit will destroy it. Compare teletherapy.... contact therapy
an approach that combines many of the different treatments (such as compression and physiotherapy) used to minimize the pain and swelling associated with *lymphoedema following breast surgery and radiotherapy. There are two phases: reduction (which lasts up to 12 weeks) and maintenance (which continues for life).... decongestive therapy
a psychoactive drug produced by minor chemical modification of existing illegal substances so as to circumvent prohibitive legislation. These drugs are manufactured in secret laboratories for profit, without regard to any probable medical and social dangers to the consumers.... designer drug
(DOT) see tuberculosis.... directly observed therapy
(DMARD) any of various drugs used in the treatment of rheumatic disease: they affect the progression of the disease by suppressing the disease process. DMARDs include drugs affecting the immune response (immunomodulators), such as *immunosuppressants (e.g. methotrexate) and *cytokine inhibitors; *gold salts; *penicillamine; *sulfasalazine; and *hydroxychloroquine.... disease-modifying antirheumatic drug
any drug that damages or destroys cells: usually refers to those drugs used to treat various types of cancer. There are various classes of cytotoxic drugs, including *alkylating agents (e.g. *chlorambucil, *cyclophosphamide, *melphalan), *antimetabolites (e.g. *fluorouracil, *methotrexate, *mercaptopurine), *anthracycline antibiotics (e.g. *doxorubicin, *daunorubicin, *dactinomycin), *vinca alkaloids, and platinum compounds (e.g. *carboplatin, *cisplatin). Other cytotoxic drugs include *taxanes and *topoisomerase inhibitors, and some *monoclonal antibodies (e.g. *bevacizumab, *trastuzumab) have cytotoxic activity. All these drugs offer successful treatment in some conditions and help reduce symptoms and prolong life in others. Cytotoxic drugs destroy cancer cells by interfering with cell division, but they also affect normal cells, particularly in bone marrow (causing *myelosuppression), hair follicles (causing hair loss), the stomach lining (resulting in severe nausea and vomiting), mouth (causing soreness), and fetal tissue (they should not be taken during the later stages of pregnancy). Dosage must therefore be carefully controlled. See also chemotherapy.... cytotoxic drug
see stent.... drug-eluting stent
lowered threshold or heightened sensitivity to the normal pharmacological action and dosage of a drug. It is unpredictable but there is some evidence of familial history.... drug intolerance
(DAPT) aspirin prescribed at the same time as another oral *antiplatelet drug (e.g. clopidogrel, prasugrel, ticagrelor) for patients deemed to be at temporarily increased risk of coronary or stent thrombosis (typically following *acute coronary syndrome or new coronary stent implantation). After a prespecified time (usually 12 months), the aspirin is continued and the other antiplatelet drug is stopped.... dual antiplatelet therapy
(EMDR) a type of psychotherapy used for the treatment of significant anxiety or distress caused by traumatic events or in the context of *post-traumatic stress disorder. The aim is to separate the emotional from the actual memory of the event in order to reduce the anxiety related to the memory.... eye movement desensitization and reprocessing therapy
(FDA) in the USA, the federal agency within the *Department of Health and Human Services responsible for ensuring that foods are safely edible; that medications (for humans and animals), biological products, and medical devices are safe and effective; and that cosmetics and electronic products that emit radiation are safe. The FDA is also responsible for ensuring the accuracy of the advertisements and labelling related to these products.... food and drug administration
the support and rehabilitation of people with hearing difficulties, tinnitus, or vertigo. It includes supplying help with acclimatizing to *hearing aids, teaching lip-reading, advising on *environmental hearing aids, and offering general information and advice regarding the auditory system. Other functions are to explain such conditions as *Ménière’s disease and *otosclerosis and to provide *tinnitus retraining therapy (TRT) and other forms of tinnitus management.... hearing therapy
(ITU, intensive care unit) a hospital unit designed to give intensive care, provided by specialist multidisciplinary staff, to a selected group of seriously ill patients or to those in need of special postoperative techniques (e.g. those patients undergoing complex heart or lung procedures).... intensive therapy unit
a form of *diathermy using electromagnetic waves of extremely short wavelength. In modern apparatus the electric currents induced in the tissues have frequencies of up to 25,000 million cycles per second.... microwave therapy
see NSAID.... nonsteroidal anti-inflammatory drug
(oral antihyperglycaemic drug) one of the group of drugs that reduce the level of glucose in the blood and are taken by mouth for the treatment of type 2 *diabetes mellitus. They include the *sulphonylurea group (e.g. glibenclamide, gliclazide), metformin (a *biguanide), *alpha-glucosidase inhibitors, *meglitinides, *thiazolidinediones, *DPP-IV inhibitors, and *SGLT-2 inhibitors.... oral hypoglycaemic drug
(OTC drug) a drug that may be purchased directly from a pharmacist without a doctor’s prescription. Current government policy is to extend the range of OTC drugs: a number have already been derestricted (e.g. ibuprofen, ranitidine) and this trend is increasing, which will place an additional advisory responsibility on pharmacists.... over-the-counter drug
(PERT) a therapeutic approach using supplements of the digestive enzymes lipase, amylase, and protease (Creon, Pancrex), which are given when there is insufficient endogenous production of pancreatic enzymes: for example, to patients with pancreatic cancer or cystic fibrosis. The capsules must be taken with all meals and snacks to be effective. PERT treats the symptoms of *steatorrhoea.... pancreatic enzyme replacement therapy
a type of radiotherapy that uses a beam of protons. These charged particles are produced by a *cyclotron and penetrate only a predictable distance into the body depending on the proton energy. This is the radiotherapy treatment of choice for many childhood cancers, particularly brain and spinal tumours, as it can avoid more normal tissue and reduce the risk of long-term complications (including secondary malignancy) compared with photon (X-ray) beams.... proton therapy
(PRRT) a type of radiotherapy used to treat neuroendocrine tumours (NETs; see neuroendocrine system). A *radionuclide is combined with a relevant *peptide to create a so-called radiopeptide, which is injected into the patient’s bloodstream. Because NETs have an overexpression of peptide receptors, the radiopeptide binds to the tumour, delivering a high dose of radiation directly to the cancer cells. The chief merit of PRRT is this ability to target delivery of radionuclides for highly localized treatment. A similar technique, using a gamma emitter as the radionuclide, can be used for locating and imaging NETs.... peptide receptor radionuclide therapy
the administration of an estimated amount of the radioactive isotope iodine-131 as a drink in order to treat an overactive thyroid gland (see thyrotoxicosis). The iodine concentrates in the thyroid and thus delivers its beta radiation locally, with little effect on other tissues. The gland will shrink and become euthyroid over the succeeding 8–12 weeks but there is a high incidence of subsequent hypothyroidism (up to 80%), which requires lifetime treatment with thyroxine. The treatment cannot be used if there is any suspicion of pregnancy, and the patient must stay away from young children and pregnant women for around 10 days after administration. Despite these drawbacks, radioactive iodine remains a popular form of treatment for any cause of hyperthyroidism.... radioactive iodine therapy
a combination of treatments in which one type of therapy is ‘sandwiched’ between exposures to another therapy. For example, surgical removal of a tumour may be ‘sandwiched’ between pre- and postoperative courses of chemotherapy. See also combined therapy.... sandwich therapy
see radioembolization.... selective internal radiation therapy
the treatment of patients who have problems with communication or eating or drinking because of congenital causes, accidents, or illness (e.g. stroke). Speech and language therapists are *allied health professionals who have special training in this field.... speech and language therapy
provision of a less harmful alternative to a drug or remedy that a patient has been receiving. It is used when the patient has become addicted to a drug or is placing too much reliance upon a particular remedy. An example is the replacement of heroin in an opioid-dependent patient with methadone.... substitution therapy
see sulphonamide.... sulpha drug
(TRT) a method of treating *tinnitus that embraces a range of techniques, including explanation, counselling, relaxation techniques, meditation, and sound therapy.... tinnitus retraining therapy
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