(germinoma, gonocytoma) n. a malignant tumour of the ovary, thought to arise from primitive germ cells; it is homologous to the *seminoma of the testis. About 15% of such tumours affect both ovaries; outside the ovary they have been recorded in the anterior mediastinum and in the pineal gland. Dysgerminomas may occur from infancy to old age, but the average age of patients is about 20 years. Treatment is by oophorectomy, with chemotherapy for residual disease.
a tumour arising in *germ cells, commonly in the testis and ovary but also found at other sites. Examples are *teratomas, *seminomas, *dysgerminomas, and *choriocarcinomas. They may be benign or malignant and typically occur in children and young adults. Tumour markers, including *alpha-fetoprotein and beta *human chorionic gonadotrophin, can be used to monitor disease.... germ cell tumour
n. a malignant tumour of the testis, appearing as a swelling, often painless, in the scrotum. It tends to occur in an older age group than the *teratomas. The treatment for localized disease is surgery involving removal of the testis (see orchidectomy). Secondary tumours in the lungs can be treated with chemotherapy and radiotherapy to the draining lymph nodes. A similar tumour occurs in the ovary (see dysgerminoma).... seminoma
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