Uses They are used in various in?ammatory conditions such as eczema (see DERMATITIS), when the skin becomes hard, cracked, and painful. They may be used in the form of a dusting powder, an oil or an ointment.
Uses They are used in various in?ammatory conditions such as eczema (see DERMATITIS), when the skin becomes hard, cracked, and painful. They may be used in the form of a dusting powder, an oil or an ointment.
Ichthyosis vulgaris Common and inherited as a dominant trait. Beginning in early childhood, it is often associated with atopic eczema (see DERMATITIS). The limb ?exures and face are spared.
X-linked ichthyosis is much less common, more severe and appears earlier than ichthyosis vulgaris. The ?sh-like scales are larger and darker and do not spare the ?exures and face.
Ichthyosiform erythroderma Of two types and very rare: in the recessive form, the appearance at birth is of the so-called ‘collodion baby’; in the dominant form the baby is born with universally red, moist and eroded skin with an unpleasant smell. Gradually, over several months, thick scales replace the ERYTHEMA.
Treatment Minor forms are helped by constant use of EMOLLIENTS and moisturising applications. Cream containing UREA can be valuable. The rare erythrodermic patterns in the neonate require skilled intensive care as thermoregulation is disturbed and massive ?uid loss occurs through the skin. Later in childhood, oral RETINOIDS are useful.... ichthyosis
Emollients are used in creams, ointments, nasal sprays, and suppositories.... emollient
Atopic eczema is a chronic, superficial inflammation that occurs in people with an inherited tendency towards allergy. The condition is common in babies. An intensely itchy rash occurs, usually on the face, in the elbow creases, and behind the knees. The skin often scales, and small red pimples may appear. For mild cases, emollients help keep the skin soft. In severe cases, corticosteroid ointments may be used. Antihistamine drugs may reduce itching. Excluding certain foods from the diet may be helpful. Atopic eczema often clears up on its own as a child grows older.
Nummular eczema usually occurs in adults. The cause is unknown. It produces circular, itchy, scaling patches anywhere on the skin, similar to those of tinea (ringworm). Topical corticosteroids may reduce the inflammation, but the disorder is often persistent.
Hand eczema is usually caused by irritant substances such as detergents, but may occur for no apparent reason. Itchy blisters develop, usually on the palms, and the skin may become scaly and cracked. Hand eczema usually improves if emollients are used and cotton gloves with rubber gloves over them are wornwhen coming into contact with irritants. If the eczema is severe, corticosteroids may be prescribed.
Stasis eczema occurs in people with varicose veins. The skin on the legs may become irritated, inflamed, and discoloured. The most important factor is swelling of the legs, which may be controlled with compression bandages or stockings. Ointments containing corticosteroids may give temporary relief.... eczema
People should be aware that normal bowel habits vary greatly, from twice a day to once every two or even three days. Any change from normal frequency to irregular or infrequent defaecation may signal constipation. Furthermore, before laxatives are prescribed, it is essential to ensure that the constipation is not the result of an underlying condition producing ‘secondary’ constipation. Individuals should not use laxatives too often or indiscriminately; persistent constipation is a reason to seek medical advice.
Bulk laxatives include bran and most high-?bre foods, such as fruit, vegetables and wholemeal foods. These leave a large indigestible residue that holds water in the gut and produces a large soft stool. Isphaghula husk, methyl cellulose and stercula are helpful when bran is ine?ective. Inorganic salts such as magnesium sulphate (Epsom Salts) have a similar e?ect.
Stimulant laxatives – for example, bisacodyl, senna and docusate sodium – stimulate PERISTALSIS, although the action may be accompanied by colicky pains.
Faecal softeners (emollients) There are two groups: surface active agents such as dioctyl sodium and sulphosuccinate which retain water in the stools and are often combined with a stimulant purgative; and liquid para?n which is chemically inert and is said to act by lubrication.
Osmotic laxatives These substances act by holding ?uid in the bowel by OSMOSIS, or by altering the manner in which water is distributed in the FAECES. Magnesium salts are used to produce rapid bowel evacuation, although one of them, magnesium hydroxide, should be used only occasionally. Phosphate or sodium citrate enemas (see ENEMA) can be used for constipation, while the former is used to ensure bowel evacuation before abdominal radiological procedures, endoscopy and surgery.... laxatives
Antipruritics may be applied as creams and emollients and may contain corticosteroid drugs, antihistamine drugs, or local anaesthetics.
Oral antihistamines may also be used to relieve itching.... antipruritic drugs
Irregular, fine, scaly, pale patches appear on the face.
Caused by mild eczema, it usually clears up with emollients.... pityriasis alba
Treatment The ?rst aim is to identify and treat the cause, whether local or systemic. Once the cause has been dealt with, symptomatic treatment may be required to break the cycle of itching, scratching and itching; topical steroid ointments and occlusive dressings help to prevent scratching. For dry skin, emollients (see OINTMENTS) are useful. Local anaesthetics (see under ANAESTHESIA) provide relief but may cause allergic reactions, and systemic ANTIHISTAMINE DRUGS at night can help.... pruritus
Others appear under their appropriate alphabetical headings: ACNE; ALBINISM; ALOPECIA; ALOPECIA AREATA; APHTHOUS ULCER; BASAL CELL CARCINOMA; BOILS (FURUNCULOSIS); BOWEN’S DISEASE; CALLOSITIES; CANDIDA; CHEILOSIS; CHEIRAPOMPHOLYX; DANDRUFF; DERMATOFIBROMA; DERMATOMYOSITIS; DERMATOPHYTES; DERMOGRAPHISM; ECTHYMA; ERYSIPELAS; ERYTHEMA; ERYTHRASMA; ERYTHRODERMA; ESCHAR; EXANTHEM; FUNGAL AND YEAST INFECTIONS; HAND, FOOT AND MOUTH DISEASE; HERPES GENITALIS; HERPES SIMPLEX; HERPES ZOSTER; IMPETIGO; INTERTRIGO; KELOID; KERATOSIS; LARVA MIGRANS; LICHEN; LUPUS; MADURA FOOT; MELANOMA; MILIARIA; MOLLUSCUM CONTAGIOSUM; MOLE; MYCOSIS FUNGOIDES; NAEVUS; ORF; PEDICULOSIS; PEMPHIGUS; PHOTOCHEMOTHERAPY; PHOTODERMATOSES; PITYRIASIS; PORPHYRIAS; PRURITUS; PSORIASIS; RINGWORM; ROSACEA; SARCOIDOSIS; SCABIES; SCLERODERMA; URTICARIA; VITILIGO; WARTS; XANTHOMATA.
Skin cancer Primary cancer is common and chronic exposure to ultraviolet light is the most important cause. BASAL CELL CARCINOMA is the most common form; squamous cell carcinoma is less common and presents as a growing, usually painless nodule which may ulcerate. Squamous cancer may spread to regional lymph glands and metastasise, unlike basal cell cancer. Occupational exposure to chemical carcinogens may cause squamous carcinoma – for example, cancer from pitch warts or the scrotal carcinoma of chimney sweeps exposed to coal dust in earlier centuries. Squamous carcinoma of the lip is associated with clay-pipe smoking.
Cancer may arise from the population of melanocytes of the skin (see MELANOCYTE; MELANOMA).
Apart from these three most frequent forms of skin cancer, various forms of cancer can arise from cells of the dermis, of which LYMPHOMA is the most important (see also MYCOSIS FUNGOIDES).
Lastly, secondary deposits from internal cancer, particularly from the breast, may metastasise to the skin.
Dermatitis and eczema These are broadly synonymous, and the terms are frequently interchangeable. Eczema is a pattern of in?ammation with many potential causes. Dermatitis is commonly used to suggest an eczema caused by external factors; it is a common pattern of in?ammation of the skin characterised by redness and swelling, vesiculation (see VESICLE), and scaling with intense itching and often exudation (weeping). Fissuring, thickening (licheni?cation – see LICHEN) and secondary bacterial infection may follow. Dermatitis can affect any part of the body. It may be genetically detemined or due to other ‘internal’ factors, such as venous HYPERTENSION in a leg, or stress. Often it is ‘external’ in origin – due to strong irritants or chemical allergens. (See also ALLERGY; ALLERGEN.) ATOPIC DERMATITIS is genetic in origin and usually begins in infancy. It may persist for years, and ASTHMA, allergic RHINITIS and conjunctivitis (see under EYE, DISORDERS OF) – ‘hay fever’ – may be associated. Atopic children tend to have multiple allergies, especially to inhaled allergens such as house-dust mite, cat and dog dander and pollens. Allergy to foods is less common but potentially more dangerous, especially if to nuts, when it can cause acute URTICARIA or even ANAPHYLAXIS. Atopic subjects are particularly prone to persistent and multiple verrucae (see WARTS) and mollusca (see MOLLUSCUM CONTAGIOSUM) and to severe HERPES SIMPLEX infections. (See also ATOPY.)
EXFOLIATE DERMATITIS (PITYRIASIS RUBRA)
Generalised exfoliation and scaling of the skin, commonly with ERYTHEMA. Drugs may cause it, or the disorder may be linked with other skin diseases such as benign dermatoses and lupus erythematosus (see under LUPUS). SUMMER POMPHOLYX is an acute vesicular eczema of the palms and soles recurring every summer. Inhaled allergens are a frequent cause. VENOUS (STASIS) DERMATITIS begins on a lower calf, often in association with PURPURA, swelling and sometimes ulceration. Chronic venous hypertension in the leg, consequent on valvular incompetence in the deep leg veins owing to previous deep vein thrombosis (see VEINS, DISEASES OF), is the usual cause. NEURODERMATITIS A pattern of well-de?ned plaques of licheni?ed eczema particularly seen on the neck, ulnar forearms or sides of the calves in subjects under emotional stress. IRRITANT CONTACT DERMATITIS Most often seen in an industrial setting (occupational dermatitis), it is due to damage by strong chemicals such as cutting oils, cement, detergents and solvents. In almost all cases the hands are most severely affected. ALLERGIC CONTACT DERMATITIS, in contrast, can affect any part of the body depending on the cause – for example, the face (cosmetics), hands (plants, occupational allergens) or soles (rubber boots). Particularly common allergens include metals (nickel and chromate), rubber addititives, and adhesives (epoxy resins).
Treatment Avoidance of irritants and contact allergens, liberal use of EMOLLIENTS, and topical application of corticosteroid creams and ointments (see CORTICOSTEROIDS) are central.... skin, diseases of
Many skin conditions, including chickenpox, urticaria (nettle rash), and eczema, produce an itchy rash. Generalized skin itchiness can be a result of diabetes mellitus, kidney failure, jaundice, and thyroid disorders.
Pruritus ani (itching around the anal region) occurs with haemorrhoids and anal fissure. Threadworm infestation is the most likely cause of anal itching in children. Pruritus vulvae (itching of the external genitalia in women) may be due to candidiasis, hormonal changes, or to use of spermicides or vaginal ointments and deodorants. Insect bites, lice, and scabies infestations cause intense itching.
Specific treatment for itching depends on the underlying cause. Cooling lotions, such as calamine, relieve irritation; emollients reduce dryness.... itching