End-plate: From 1 Different Sources
n. the area of muscle cell membrane immediately beneath the motor nerve ending at a *neuromuscular junction. Special receptors in this area trigger muscular contraction when the nerve ending releases its *neurotransmitter.
The smallest type of blood cell, also called a thrombocyte. Platelets play a major role in blood clotting.... platelet
Platelets are the small, rather uniform fragments of large bone marrow cells that aid the blood in coagulation, hemostasis, inflammation, and thrombus formation. Mild subclotting and sticking is a common early condition that can lead to thrombosis, atherosclerosis, and strokes, and can be helped by an aspirin a day, better fat digestion, and Ceanothus.... platelet aggregation
Blood platelets, or thrombocytes, are small spherical bodies in the BLOOD, which play an important part in the process of its COAGULATION. Normally, there are around 300,000 per cubic millimetre of blood.... platelets
The clumping together of platelets (small, sticky blood particles). Aggregation is the 1st stage of blood clotting and helps to plug injured vessels. Inappropriate aggregation can have adverse effects; for example, if aggregation occurs in an artery, it may result in a thrombosis.... aggregation, platelet
see ethmoid bone.... cribriform plate
see physis.... growth plate
the strip of ectoderm lying along the central axis of the early embryo that forms the *neural tube and subsequently the central nervous system.... neural plate
the process whereby platelets adhere to collagen released from endothelial cells in damaged blood vessels and aggregate to form a plug. An important metabolic pathway in platelets converts membrane phospholipids to *thromboxane A2 (TXA2), which can activate platelets. ADP, released from platelet granules, and *thrombin are other activators. The adhesive and aggregation reactions of platelets are mediated through surface membrane glycoproteins (Glp), Glp Ib and Glp IIb/IIIa. Aspirin acts as an *antiplatelet drug by irreversibly inhibiting one of the enzymes of this pathway, cyclo-oxygenase. Clopidrogel inhibits the ADP receptor on platelet membranes, and *abciximab blocks platelet aggregation by inhibiting Glp IIb/IIIa (see illustration overleaf).... platelet activation
(PDGF) see growth factor.... platelet-derived growth factor
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