In?ammation of the inner coat of an artery. (See ARTERIES, DISEASES OF.)
n. chronic inflammation of the inner (intimal) portion of the wall of an artery, which most often results from late syphilis. Thickening of the wall produces progressive arterial obstruction and symptoms from inadequate blood supply to the affected part (*ischaemia). The arteries to the brain are often involved, giving rise to meningovascular syphilis. Endarteritis of the aorta may obstruct the mouths of the coronary arteries, supplying the heart. Endarteritis of the arteries to the wall of the aorta (the vasa vasorum) contributes to *aneurysm formation. The syphilitic infection may be eradicated with penicillin.
n. thrombosis complicating *endarteritis, seen in temporal *arteritis, *polyarteritis nodosa, and syphilis. It may cause death of part of the organ supplied by the affected artery.... thromboendarteritis