Endodermal sinus tumour Health Dictionary

Endodermal Sinus Tumour: From 1 Different Sources


a rare tumour of fetal remnants of the ovaries or testes. In women it is an aggressive malignant ovarian tumour that develops in adolescence and may secrete alpha-fetoprotein and human chorionic gonadotrophin, which can be used as *tumour markers. It is treated by oophorectomy with adjuvant chemotherapy.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Tumour

A mass or swelling. The lump can be a neoplasm (benign or malignant) or a tumour can be a mass due to an infection or inflammation.... tumour

Sinus

A term applied to narrow cavities of various kinds, occurring naturally in the body, or resulting from disease. Thus it is applied to the air-containing cavities which are found in the frontal, ethmoidal, sphenoidal and maxillary bones of the SKULL, and which communicate with the NOSE. The function of these paranasal sinuses, as they are known, is doubtful, but they do lighten the skull and add resonance to the voice. They enlarge considerably around puberty and in this way are a factor in the alteration of the size and shape of the face. The term is also used in connection with the wide spaces through which the blood circulates in the membranes (MENINGES) of the BRAIN. Cavities which are produced when an ABSCESS has burst, but remain unhealed, are also known as sinuses (see also FISTULA).... sinus

Cavernous Sinus

A channel for venous blood placed either side of the sphenoid bone at the base of the SKULL behind the eye sockets. Blood drains into it from the eye, the nose, the brain and part of the cheek, and leaves via the internal jugular and facial veins. Sometimes the sinus becomes blocked by a blood clot (thrombus), usually a complication of a nearby bacterial infection. A potentially serious condition, it should be treated with thrombolysis and antibiotics.... cavernous sinus

Frontal Sinus

One of the airspaces that form the paranasal sinuses (see SINUS) within some of the frontal bones of the skull. These sinuses are lined with mucous membrane and open into the nasal cavity.... frontal sinus

Sinus Tachycardia

A regular heart rate of 100 or more beats a minute, caused by increased electrical activity in the SINOATRIAL NODE (see also HEART). This level of tachycardia is normal during and just after exercise, and may also be caused by stress or anxiety. If tachycardia persists when the person is resting, it may be due to underlying disease such as thyrotoxicosis (see under THYROID GLAND, DISEASES OF) and investigation is advisable.... sinus tachycardia

Wilms’ Tumour

Also called nephroblastoma. This is the commonest kidney tumour in infancy. It is a malignant tumour, which occurs in around one per 10,000 live births. The survival rate with modern treatment (removal of the kidney followed by radiotherapy and chemotherapy) is now around 80 per cent.... wilms’ tumour

Cavernous Sinus Thrombosis

Thrombosis arising in the cavernous sinus of the sphenoid bone in the head.

Cause: Septicaemia or infected embolism conveyed from elsewhere – veins of the face, sinuses, head. May be a complication of meningitis.

Symptoms: headache, nausea, swelling of eyelids and forehead, pupils distended, veins of temples prominent, fever with severe constitutional disturbance.

Prognosis: usually fatal in the absence of orthodox antibiotics, but anti-staphylococcal herbs are helpful. Tinctures. Formula. Echinacea 3; Goldenseal 2; Myrrh (Tincture) 1. 1 teaspoon in water every 2 hours (acute). Thrice daily (chronic).

Treatment by or in liaison with general medical practitioner. ... cavernous sinus thrombosis

Brain Tumour

An abnormal growth in or on the brain. Tumours may be primary growths arising directly from tissues within the skull or metastases (secondary growths) that have spread from tumours elsewhere in the body. The cause of primary brain tumours is not known. About 60 per cent are gliomas (frequently cancerous), which arise from the brain tissue. Other primary tumours include meningiomas, acoustic neuromas, and pituitary tumours. Most of these tumours are noncancerous, but their size can cause local damage. Certain types of primary brain tumour mainly affect children. These include 2 types of glioma called medulloblastoma and cerebellar astrocytoma. Primary brain tumours virtually never spread (metastasize) outside the central nervous system.

Symptoms include muscle weakness, loss of vision, or other sensory disturbances, speech difficulties, and epileptic seizures. Increased pressure within the skull can cause headache, visual disturbances, vomiting, and impaired mental functioning. Hydrocephalus may occur.

When possible, primary tumours are removed by surgery after opening the skull (see craniotomy).

In cases where a tumour cannot be completely removed, as much as possible of it will be cut away to relieve pressure.

For primary and secondary tumours, radiotherapy or anticancer drugs may also be given.

Corticosteroid drugs are often prescribed temporarily to reduce the size of a tumour and associated brain swelling.... brain tumour

Desmoid Tumour

A growth, usually in the abdominal wall.

The tumour is hard, with a well-defined edge.

The tumours occur most frequently in women who have had children.

They may also arise at the sites of old surgical incisions.

Surgical removal is the usual treatment.... desmoid tumour

Germ Cell Tumour

A growth comprised of immature sperm cells in the male testis or of immature ova in the female ovary. A seminoma is one type of germ cell tumour (see testis, cancer of).... germ cell tumour

Glomus Tumour

A small, bluish swelling in the skin, usually on a finger or toe near or under the nail, which is tender to touch and more painful if the limb is hot or cold.

The cause is overgrowth of the nerve structures that normally control blood flow and temperature in the skin.

The tumours are harmless but are surgically removed.... glomus tumour

Mixed Tumour

A neoplasm with a number of different cell types undergoing cancerous change.... mixed tumour

Paranasal Sinus

Sited within some of the bones of the SKULL, these are spaces ?lled with air and lined by MUCOUS MEMBRANE. The sinuses comprise frontal and maxillary (a pair of each), ethmoidal (a group of small spaces), and two sphenoid sinuses. They drain into the nasal cavities (see NOSE). When a person has an upper respiratory infection, the sinuses sometimes become infected: this causes pain, purulent discharge from the nose and obstruction of the nasal passages (see SINUSITIS). Generally all that is required is a decongestant and antibiotic but, occasionally, infection may spread to produce a cerebral abscess or cerebral venous sinus thrombosis (see BRAIN, DISEASES OF).... paranasal sinus

Pilonoidal Sinus

A SINUS that contains hairs, usually occurring in the cleft between the buttocks. It may get infected and cause considerable pain. Treatment is by antibiotics and, if necessary, surgical removal.... pilonoidal sinus

Anti-tumours

See: ANTI-NEOPLASTICS. ... anti-tumours

Adrenal Tumours

Cancerous or noncancerous tumours in the adrenal glands, usually causing excess secretion of hormones. Adrenal tumours are rare. Tumours of the adrenal cortex may secrete aldosterone, causing primary aldosteronism, or hydrocortisone, causing Cushing’s syndrome. Tumours of the medulla may cause excess secretion of adrenaline and noradrenaline. Two types of tumour affect the medulla: phaeochromocytoma and neuroblastoma, which affects children. These tumours cause intermittent hypertension and sweating attacks. Surgical removal of a tumour usually cures these conditions.... adrenal tumours

Apud Cell Tumour

A growth composed of cells that produce various hormones. These cells, amine precursor uptake and decarboxylation (APUD) cells, occur in different parts of the body. Some tumours of the thyroid gland, pancreas, and lungs are cell tumours, as are a carcinoid tumour (see carcinoid syndrome) and phaeochromocytoma (a type of adrenal tumour).... apud cell tumour

Bone Tumour

A bone swelling that may be cancerous (see bone cancer) or noncancerous.

The most common type of noncancerous bone tumour is an osteochondroma.

Other types are osteoma and chondroma (see chondromatosis).

Treatment is only necessary if the tumour becomes very large or causes symptoms by pressing on other structures.

In such cases, the tumour can be removed by surgery.

Osteoclastoma (also called a giant cell tumour), which usually occurs in the arm or leg of a young adult, is tender and painful and has to be removed.... bone tumour

Dermoid Tumour

See dermoid cyst.... dermoid tumour

Tea For Sinus Congestion

Sinus congestion causes a stuffy sensation in your nose as well as in your throat. This affection consists of mucus accumulations in your respiratory ways and it can be triggered by many problems, from colds, flu, to pulmonary edema and some types of cancer. However, in order to find out more about what’s bothering your health, schedule an appointment with your doctor and don’t try to medicate yourself. How a Tea for Sinus Congestion Works A Tea for Sinus Congestion’s main purpose is to dissolve all mucus accumulations and bring relief to your pain. The active constituents in these teas have an important acids and mineral level that could calm the affected areas and induce a state of calmness to your entire body. Efficient Tea for Sinus Congestion In order to work properly, a Tea for Sinus Congestion needs to be both efficient and one hundred percent safe. A tea that is rich in tannins, nutrients, antioxidant, natural enzymes and minerals (magnesium, iron, manganese) could be a perfect choice, especially because it can treat other diseases as well. But if you don’t know which teas have the ability to treat your problems, here’s a list to choose from: - Eucalyptus Tea – is well known thanks to its capacity to dissolve mucus accumulations and restore the initial health. Eucalyptus is also used as an ingredient for the international cuisine as well as in the cosmetic industry to produce face cleansers and anti-aging creams. However, don’t drink more than 3 cups per day in order to avoid developing teeth soreness. - Peppermint Tea – is a well known panacea with a lovely fragrance and a pleasant taste which can dissolve inflammations and prevent them from forming again. You can also use it to treat colds, flu, sore throats, diarrhea, gastritis, fever and menstrual pains. Plus, it’s one hundred percent safe, so you can drink as much as you want. - Echinacea Tea –this Tea for Sinus Congestion stimulates the production of blood cells and antibodies to flush all infection triggers out of your system. A recent study showed recently that people who took a treatment based on Echinacea healed their problems better than other people who only took traditional pills! So next time you’re looking for sinus congestion remedies, check out the teashops instead of pharmacies! Tea for Sinus Congestion Side Effects When taken properly, these teas are generally safe. However, exceeding the number of cups recommended per day may lead to a number of affections, such as upset stomach, vomiting or skin rash. Talk to your doctor or to an herbalist before starting any type of herbal remedies and be well informed of the risks! If you’ve been taking one of these teas for a while and you’re experiencing some unusual reactions, ask for medical assistance as soon as possible! If you have the green light from your doctor and there’s nothing that could go wrong, choose a Tea for Sinus Congestion that fits best your medical problems and enjoy its benefits!... tea for sinus congestion

Bladder Tumours

Growths originating in the inner lining of the bladder. Many are papillomas (small wart-like growths), which tend to recur and will eventually become cancerous. Other, more malignant, growths may extend not only into the bladder cavity but may also spread through the bladder wall to involve nearby organs such as the colon, rectum, prostate gland, or uterus.

Bladder cancer is more common in smokers and workers in the dye and rubber industries. Haematuria (blood in the urine) is the main symptom of bladder cancer. A tumour may obstruct the entry of a ureter into the bladder, causing back pressure and pain in the kidney region, or may obstruct the urethral exit, causing difficulty in passing, or retention of, urine.

Bladder tumours are diagnosed using cystoscopy and biopsy of the abnormal area. If small, they can be treated by heat or surgically during cystoscopy. They tend to recur at the same or other sites within the bladder, so that regular follow-up cystoscopy is needed. Bladder tumours that have spread through the bladder wall may be treated by radiotherapy or by surgical removal of part or all of the bladder.... bladder tumours

Eye Tumours

Tumours of the eye are rare. When eye tumours do occur, they are usually cancerous and painless.

Retinoblastoma is a cancerous tumour of the retina that occurs in one or both eyes and most often affects children. It may be treated by radiotherapy, laser treatment, or cryosurgery, but the eye may have to be removed to prevent spread of the tumour.

Malignant melanoma is a cancer of the choroid. It usually affects older people. There are no symptoms in the early stages, but it eventually causes retinal detachment and distortion of vision. Small tumours can be treated by laser, but the eye may need to be removed to avoid spread of the tumour.

Secondary eye tumours occur when cancer elsewhere in the body spreads to the eye. Symptoms depend on the tumour’s location and growth rate. It may be controlled by radiotherapy.

Basal cell carcinoma is the most common type of tumour affecting the eyelid. It usually has a crusty central crater and a rolled edge. In the early stages, treatment may be possible by surgery, radiotherapy, or cryosurgery.... eye tumours

Intestine, Tumours Of

Cancerous or noncancerous growths in the intestine. Cancerous tumours commonly affect the large intestine (see colon, cancer of; rectum, cancer of); the small intestine is only rarely affected. Lymphomas and carcinoid tumours (leading to carcinoid syndrome) may sometimes develop in the intestine; noncancerous tumours include polyps in the colon, and adenomas, leiomyomas, lipomas, and angiomas in the small intestine.... intestine, tumours of

Lung Tumours

Growths in the lungs. These tumours may be either cancerous (see lung cancer) or noncancerous.Cancerous lung tumours are usually associated with tobacco-smoking.

Noncancerous tumours occur less frequently than cancers.

The most common form of noncancerous tumour is a bronchial adenoma, which arises in the lining of a bronchus.

Adenomas often cause bronchial obstruction; affected people may also cough up blood.

Treatment involves surgical removal of the tumour.

Other rare noncancerous tumours include fibromas (which consist of fibrous tissue) and lipomas (which consist of fatty tissue).

No treatment is necessary unless the tumours are causing problems.... lung tumours

Pituitary Tumours

Growths in the pituitary gland. Pituitary tumours are rare, and mostly noncancerous, but tumour enlargement can put pressure on the optic nerves, causing visual defects.

The causes of pituitary tumours are unknown. They may lead to inadequate hormone production, causing problems such as cessation of menstrual periods or reduced sperm production. They may also cause the gland to produce excess hormone. Overproduction of growth hormone causes gigantism or acromegaly; too much thyroid-stimulating hormone (TSH) can lead to hyperthyroidism. Investigations include blood tests, X-rays, MRI of the pituitary, and usually also vision tests. Treatment may be by surgical removal of the tumour, radiotherapy, hormone replacement, or a combination of these techniques. The drug bromocriptine may be used; it can reduce production of certain hormones and shrink some tumours.... pituitary tumours

Sick Sinus Syndrome

Abnormal function of the heart’s sinoatrial node that leads to episodes of bradycardia (slow heart-rate), alternating bradycardia and tachycardia (fast heart-rate), or very short episodes of cardiac arrest.

The cause is usually coronary artery disease, but may be a cardiomyopathy.

Symptoms may include lightheadedness, fainting, and palpitations.

The diagnosis is confirmed by a 24-hour ECG recording.

Treatment is usually by antiarrhythmic drugs and the fitting of an artificial pacemaker.... sick sinus syndrome

Sinus Bradycardia

A slow, but regular heart-rate (less than 60 beats per minute) caused by reduced electrical activity in the sinoatrial node. Sinus bradycardia is normal in athletes, but in others it may be caused by hypothyroidism, a myocardial infarction, or by drugs such as beta-blockers or digoxin.... sinus bradycardia

Sinus, Facial

Any of the air-filled cavities in the bones surrounding the nose. These include 2 frontal sinuses in the

lower forehead; 2 ethmoidal sinuses between the eyes; 2 maxillary sinuses in the cheekbones; and the sphenoidal sinuses in the skull behind the nose. Mucus drains from each sinus along a channel that opens into the nose. Infection of a sinus causes sinusitis.... sinus, facial

Skin Tumours

A growth on or in the skin that may be cancerous (see skin cancer) or noncancerous.

Keratoses and squamous papillomas are common types of noncancerous tumour; other types include sebaceous cysts, cutaneous horns, keratoacanthomas, and haemangiomas.... skin tumours

Trophoblastic Tumour

A growth arising from the tissues that develop into the placenta. The most common type of trophoblastic tumour is a hydatidiform mole. (See also choriocarcinoma.)... trophoblastic tumour

Tumour-specific Antigen

A substance secreted by a specific type of tumour that can be detected in the blood and may be used to help monitor a patient’s response to therapy.

Alpha-fetoprotein is an example of a tumour-specific antigen.... tumour-specific antigen

Wilms’ Tumour

A type of kidney cancer, also called nephroblastoma, that occurs mainly in children.... wilms’ tumour

Carotid Sinus

a pocket in the wall of the carotid artery, at its division in the neck, containing receptors that monitor blood pressure (see baroreceptor). When blood pressure is raised, impulses travel from the receptors to the vasomotor centre in the brain, which initiates a reflex *vasodilatation and slowing of heart rate to lower the blood pressure to normal.... carotid sinus

Cerebral Venous Sinus Thrombosis

the presence of thrombosis in the dural venous sinuses, which drain blood from the brain. Symptoms may include headache, abnormal vision, any of the symptoms of stroke (such as weakness of the face and limbs on one side of the body), and seizures. Treatment is with anticoagulants.... cerebral venous sinus thrombosis

Cerebral Tumour

an abnormal multiplication of brain cells. Any tumorous swelling tends to compress or even destroy the healthy brain cells surrounding it and – because of the rigid closed nature of the skull – increases the pressure on the brain tissue. Malignant brain tumours, which are much more common in children than in adults, include *medulloblastomas and *gliomas; these grow rapidly, spreading through the otherwise normal brain tissue and causing progressive neurological disability. Benign tumours, such as *meningiomas, grow slowly and compress the brain tissue. Both benign and malignant tumours commonly cause fits. Benign tumours are often cured by total surgical resection. Malignant tumours may be treated by neurosurgery, chemotherapy, and radiotherapy, but the outcome for most patients remains poor.... cerebral tumour

Endoscopic Sinus Surgery

(ESS) surgery of the *paranasal sinuses using endoscopes. Functional endoscopic sinus surgery (FESS) clears inflamed tissue from routes of sinus drainage and aeration to allow the other sinuses to return to normal.... endoscopic sinus surgery

Functional Endoscopic Sinus Surgery

(FESS) see endoscopic sinus surgery.... functional endoscopic sinus surgery

Gastrointestinal Stromal Tumour

(GIST) a rare type of sarcoma arising from the gastrointestinal tract (usually the stomach), characterized by the presence of the receptor c-kit/CD117 on the surface of the tumour cells, which stimulates division of these cells. It displays a wide range of malignant behaviour. Specific treatment is available with *tyrosine kinase inhibitors.... gastrointestinal stromal tumour

Grawitz Tumour

see renal cell carcinoma. [P. A. Grawitz (1850–1932), German pathologist]... grawitz tumour

Hilar Cell Tumour

an androgen-producing tumour of the ovary found in older women and often resulting in *virilization. Such tumours are so called as they tend to occur around the area of the ovary where the blood vessels enter (the hilum). They are usually small and are treated by surgical removal, with resolution of most of the symptoms.... hilar cell tumour

Hürthle Cell Tumour

a malignant tumour of the thyroid gland that arises from Hürthle (or Askanazy) cells, altered follicular cells of the gland that have large nuclei and stain deeply with eosin (these cells are also found in benign nodules and Hashimoto’s disease). Hürthle cell carcinoma is not as common as papillary, follicular, or anaplastic thyroid carcinomas (see thyroid cancer). [K. W. Hürthle (1860–1945), German histologist]... hürthle cell tumour

Islet Cell Tumour

any tumour arising in a cell of the pancreatic *islets of Langerhans. These tumours, which include *insulinomas, *glucagonomas, and *somatostatinomas, form one of the two major subclasses of gastrointestinal neuroendocrine tumours, the other being the *carcinoid tumours.... islet cell tumour

Klatskin Tumour

see cholangiocarcinoma. [G. Klatskin (20th century), US physician]... klatskin tumour

Krukenberg Tumour

a rapidly developing malignant growth in one or (more often) both ovaries. It is caused by the *transcoelomic spread of a primary growth in the stomach or intestine, typically an adenocarcinoma. [F. E. Krukenberg]... krukenberg tumour

Leydig Tumour

a tumour of the *interstitial (Leydig) cells of the testis. Such tumours often secrete testosterone, which in prepubertal boys causes *virilization and precocious puberty.... leydig tumour

Lindau’s Tumour

see haemangioblastoma. [A. Lindau (1892–1958), Swedish pathologist]... lindau’s tumour

Maxillary Sinus

(maxillary antrum) see paranasal sinuses.... maxillary sinus

Odontogenic Tumour

any one of a group of neoplasm tumour-like malformations arising from odontogenic tissues or their remnants. The most important example is the *ameloblastoma.... odontogenic tumour

Phantom Tumour

1. an accumulation of fluid (pleural effusion) in the lung in patients with heart failure, which resembles a lung tumour on radiological examination. 2. a swelling in the abdomen or elsewhere, caused by local muscular contraction or the accumulation of gases, that mimics a swelling caused by a tumour.... phantom tumour

Pilonidal Sinus

a short tract leading from an opening in the skin in or near the cleft at the top of the buttocks and containing hairs. The sinus may be recurrently infected, leading to pain and the discharge of pus. Treatment is by surgical opening and cleaning of the sinus.... pilonidal sinus

Raspberry Tumour

an *adenoma of the umbilicus.... raspberry tumour

Sinus Arrhythmia

a normal variation in the heart rate, which accelerates slightly on inspiration and slows on expiration. It is common in young fit individuals.... sinus arrhythmia

Sinus Rhythm

a normal heart rhythm, usually as recorded on an electrocardiogram. The *sinoatrial node, located in the right atrium, normally functions as the natural pacemaker for the heart.... sinus rhythm

Sinus Venosus

a chamber of the embryonic heart that receives blood from several veins. In the adult heart it becomes part of the right atrium.... sinus venosus

Sternomastoid Tumour

a small painless nonmalignant swelling in the lower half of the *sternomastoid muscle, appearing a few days after birth. It occurs when the neck of the fetus is in an abnormal position in the uterus, which interferes with the blood supply to the affected muscle, and it is most common after breech births. The tumour may cause a slight tilt of the head towards the tumour and turning of the face to the other side. This can be corrected by physiotherapy aimed at increasing all movements of the body, but without stretching the neck.... sternomastoid tumour

Tumour-associated Antigen

a protein produced by cancer cells. Its presence in the blood can be revealed by means of a simple blood test, aiding the diagnosis of malignant melanoma and other cancers at their earliest – and most treatable – stages of development.... tumour-associated antigen

Tumour-infiltrating Lymphocyte

(TIL) a lymphoid cell that can infiltrate solid tumours. Such cells can be cultured in vitro, in the presence of *interleukin 2, and have been used as vehicles for *tumour necrosis factor in gene therapy trials for cancer.... tumour-infiltrating lymphocyte

Tumour Marker

a substance produced by a tumour that can be used to aid detection of the tumour and to monitor its size and the effects of treatment. An example is *alpha-fetoprotein, which is used to monitor treatment of malignant *teratomas. See also CA125; CA19-9; carcino-embryonic antigen; human chorionic gonadotrophin.... tumour marker

Tumour Necrosis Factor

(TNF) either of two proteins, TNF-? or TNF-?, that function as *cytokines. Produced by macrophages, monocytes, T lymphocytes, and various other cells, they mediate many responses, including inflammation, and have a marked action against tumour cells. Anti-TNF drugs (see cytokine inhibitor) are used in the treatment of several disorders, especially rheumatoid arthritis and ankylosing spondylitis.... tumour necrosis factor

Urinogenital Sinus

the duct in the embryo that receives the ureter and the Wolffian and Müllerian ducts and opens to the exterior. The innermost portion forms most of the bladder and the remainder forms the urethra with its associated glands. Part of it may also contribute towards the vagina.... urinogenital sinus

Warthin’s Tumour

(adenolymphoma) a tumour of the parotid salivary glands, containing epithelial and lymphoid tissues with cystic spaces. [A. S. Warthin (1866–1931), US pathologist]... warthin’s tumour



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