Erysipelas Health Dictionary

In?ammation taking place in cellular tissue, and usually referring to infection in the subcutaneous tissue. A related word, cellulite, which has no medical meaning, is used in the slimming business to refer to excess fatty tissue in the arms, buttocks and thighs. (See ABSCESS; ERYSIPELAS.)... cellulitis

Ficus spp.

Moraceae

The genus Ficus constitutes an important group of trees with immense medicinal value. It is a sacred tree of Hindus and Buddhists. Among the varied number of species, the most important ones are the four trees that constitute the group “Nalpamaram”, namely, F. racemosa, F. microcarpa, F. benghalensis and F. religiosa (Athi, Ithi, Peral and Arayal respectively).

1. Ficus racemosa Linn. syn. F. glomerata Roxb.

Eng: Cluster fig, Country fig

San: Udumbarah, Sadaphalah

Hin: Gular, Umar

Ben: Jagya dumur

Mal, Tam,

Kan: Athi

Tel: Udambaramu, Paidi

Gular fig, Cluster fig or Country fig, which is considered sacred, has golden coloured exudate and black bark. It is distributed all over India. Its roots are useful in treating dysentery. The bark is useful as a wash for wounds, highly efficacious in threatened abortions and recommended in uropathy. Powdered leaves mixed with honey are given in vitiated condition of pitta. A decoction of the leaves is a good wash for wounds and ulcers. Tender fruits (figs) are used in vitiated conditions of pitta, diarrhoea, dyspepsia and haemorrhages. The latex is administered in haemorrhoids and diarrhoea (Warrier et al, 1995). The ripe fruits are sweet, cooling and are used in haemoptysis, thirst and vomiting (Nadkarni, 1954; Aiyer et al, 1957; Moos, 1976). Nalpamaradi coconut oil, Candanasava, Valiya Arimedastaila, Dinesavalyadi Kuzhambu, Abhrabhasma, Valiya candanaditaila, etc. are some important preparations using the drug (Sivarajan et al, 1994).

It is a moderate to large-sized spreading laticiferous, deciduous tree without many prominent aerial roots. Leaves are dark green and ovate or elliptic. Fruit receptacles are 2-5cm in diameter, sub- globose or pyriform arranged in large clusters on short leafless branches arising from main trunk or large branches. Figs are smooth or rarely covered with minute soft hairs. When ripe, they are orange, dull reddish or dark crimson. They have a pleasant smell resembling that of cedar apples. The bark is rusty brown with a fairly smooth and soft surface, the thickness varying from 0.5-2cm according to the age of the trunk or bark. Surface is with minute separating flakes of white tissue. Texture is homogeneously leathery (Warrier et al, 1995).

Stem-bark gives gluanol acetate, -sitosterol, leucocyanidin-3-O- -D-glucopyrancoside, leucopelargonidin-3-O- -D-glucopyranoside, leucopelargonidin -3-O- -L-rhamnopyranoside, lupeol, ceryl behenate, lupeol acetate and -amyrin acetate. Stem- bark is hypoglycaemic and anti-protozoal. Gall is CVS active. Bark is tonic and used in rinder pest diseases of cattle. Root is antidysenteric and antidiabetic. Leaf is antibilious. Latex is antidiarrhoeal and used in piles. Bark and syconium is astringent and used in menorrhagia (Husain et al, 1992).

2. Ficus microcarpa Linn. f. syn. F. retusa auct. Non. Linn.

San: Plaksah; Hin,

Ben: Kamarup;

Mal: Ithi, Ithiyal;

Tam: Kallicci, Icci;

Kan: Itti;

Tel: Plaksa

Plaksah is the Ficus species with few branches and many adventitious roots growing downward. It is widely distributed throughout India and in Sri Lanka, S. China, Ryuku Isles and Britain. Plakasah is one of the five ingredients of the group panchvalkala i.e, five barks, the decoction of which is extensively used to clear ulcers and a douche in leucorrhoea in children. This decoction is administered externally and internally with satisfactory results. Plaksah is acclaimed as cooling, astringent, and curative of raktapitta doshas, ulcers, skin diseases, burning sensation, inflammation and oedema. It is found to have good healing property and is used in preparation of oils and ointments for external application in the treatment of ulcers (Aiyer and Kolammal, 1957). The stem-bark is used to prepare Usirasava, Gandhataila, Nalpamaradi taila, Valiya marmagulika, etc. (Sivarajan et al, 1994). The bark and leaves are used in wounds, ulcers, bruises, flatulent colic, hepatopathy, diarrhoea, dysentery, diabetes, hyperdipsia, burning sensation, haemaorrhages, erysipelas, dropsy, ulcerative stomatitis, haemoptysis, psychopathy, leucorrhoea and coporrhagia (Warrier et al,1995) F. microcarpa is a large glabrous evergreen tree with few aerial roots. Leaves are short- petioled, 5-10cm long, 2-6cm wide and apex shortly and bluntly apiculate or slightly emarginate. Main lateral nerves are not very prominent and stipules are lanceolate. Fruit receptacles are sessile and globose occurring in axillary pairs. It is yellowish when ripe without any characteristic smell. Bark is dark grey or brown with a smooth surface except for the lenticels. Outer bark is corky and crustaceous thin and firmly adherent to inner tissue. Inner bark is light and flesh coloured with firbrous texture (Warrier et al, 1995). It is also equated with many other species of the genus. viz. F. Singh and Chunekar, 1972; Kapoor and Mitra, 1979; Sharma, 1983).

The bark contains tannin, wax and saponin. Bark is antibilious. Powdered leaves and bark is found very good in rheumatic headache. The bark and leaves are astringent, refrigerant, acrid and stomachic.

3. Ficus benghalensis Linn.

Eng: Banyan tree; San: Nyagrodhah, Vatah;

Hin: Bat, Bargad;

Ben: Bar, Bot; Mar: Vada; Mal: Peral, Vatavriksham;

Tam: Alamaram, Peral;

Kan: Ala;

Tel: Peddamarri;

Guj: Vad

Banyan tree is a laticiferous tree with reddish fruits, which is wound round by aerial adventitious roots that look like many legs. It is found in the Sub-Himalayan tract and Peninsular India. It is also grawn throughout India. It is widely used in treatment of skin diseases with pitta and rakta predominance. Stem-bark, root -bark, aerial roots, leaves, vegetative buds and milky exudate are used in medicine. It improves complexion, cures erysepelas, burning sensation and vaginal disorders, while an infusion of the bark cures dysentery, diarrhoea, leucorrhoea, menorrhagia, nervous disorders and reduces blood sugar in diabetes. A decoction of the vegetative buds in milk is beneficial in haemorrhages. A paste of the leaves is applied externally to abcesses and wounds to promote suppuration, while that of young aerial roots cure pimples. Young twigs when used as a tooth brush strengthen gum and teeth (Nadkarni, 1954; Aiyer and Kolammal, 1957; Mooss,1976). The drug forms an important constituent of formulations like Nalpamaradi Coconut oil, Saribadyasava, Kumkumadi taila, Khadi ra gulika, Valiyacandanadi taila, Candanasava, etc. (Sivarajan et al, 1994). The aerial roots are useful in obstinate vomiting and leucorrhoea and are used in osteomalacia of the limbs. The buds are useful in diarrhoea and dysentery. The latex is useful in neuralgia, rheumatism, lumbago, bruises, nasitis, ulorrhagia, ulitis, odontopathy, haemorrhoids, gonorrhoea, inflammations, cracks of the sole and skin diseases (Warrier et al, 1995).

It is a very large tree up to 30m in height with widely spreading branches bearing many aerial roots functioning as prop roots. Bark is greenish white. Leaves are simple, alternate, arranged often in clusters at the ends of branches. They are stipulate, 10-20cm long and 5-12.5cm broad, broadly elliptic to ovate, entire, coriaceous, strongly 3-7 ribbed from the base. The fruit receptacles are axillary, sessile, seen in pairs globose, brick red when ripe and enclosing male, female and gall flowers. Fruits are small, crustaceous, achenes, enclosed in the common fleshy receptacles. The young bark is somewhat smooth with longitudinal and transverse row of lenticels. In older bark, the lenticels are numerous and closely spaced; outer bark easily flakes off. The fresh cut surface is pink or flesh coloured and exudes plenty of latex. The inner most part of the bark adjoining the wood is nearly white and fibrous (Warrier et al, 1995).

The bark yields flavanoid compounds A, B and C; A and C are identified as different forms of a leucoanthocyanidin and compound B a leucoanthocyanin. All the 3 were effective as hypoglycaemic agents. Leaves give friedelin, -sitosterol, flavonoids- quercetin-3-galactoside and rutin. Heart wood give tiglic acid ester of taraxasterol. Bark is hypoglycemic, tonic, astringent, antidiarrhoeal and antidiabetic. Latex is antirheumatic. Seed is tonic. Leaf is diaphoretic. Root fibre is antigonorrhoeic. Aerial root is used in debility and anaemic dysentery (Husain et al, 1992).

.4. Ficus religiosa Linn.

Eng:Peepal tree, Sacred fig; San:Pippalah, Asvatthah; Hin:Pippal, Pipli, Pipar; Mal:Arayal

Ben: Asvatha;

Tam: Arasu, Asvattam;

Kan: Aswatha;

Tel: Ravi; Mar: Ashvata, Pimpala

Peepal tree or Sacred fig is a large deciduous tree with few or no aerial roots. It is common throughout India, often planted in the vicinity of the temples. An aqueous extract of the bark has an antibacterial activity against Staphylococcus aureus and Escherichia coli. It is used in the treatment of gonorrhoea, diarrhoea, dysentery, haemorrhoids and gastrohelcosis. A paste of the powdered bark is a good absorbent for inflammatory swellings. It is also good for burns. Leaves and tender shoots have purgative properties and are also recommended for wounds and skin diseases. Fruits are laxative and digestive. The dried fruit pulverized and taken in water cures asthma. Seeds are refrigerant and laxative. The latex is good for neuralgia, inflammations and haemorrhages (Warrier et al, 1995). Decoction of the bark if taken in honey subdues vatarakta (Nadkarni, 1954; Aiyer and Kolammal, 1957; Mooss, 1976; Kurup et al, 1979). The important preparations using the drug are Nalpamaradi taila, Saribadyasava, Candanasava, Karnasulantaka, Valiyamarma gulika etc (Sivarajan et al, 1994). branches bearing long petioled, ovate, cordate shiny leaves. Leaves are bright green, the apex produced into a linear-lanceolate tail about half as long as the main portion of the blade. The receptacles occurring in pairs and are axillary, depressed globose, smooth and purplish when ripe. The bark is grey or ash coloured with thin or membranous flakes and is often covered with crustose lichen patches. The outer bark is not of uniform thickness, the middle bark in sections appear as brownish or light reddish brown. The inner part consists of layers of light yellowish or orange brown granular tissue (Warrier et al, 1995).

Bark gives -sitosterol and its glucoside. Bark is hypoglycaemic. Stem bark is antiprotozoal, anthelmintic and antiviral. Bark is astringent, antigonorrheic, febrifuge, aphrodisiac and antidysenteric. Syconium, leaf and young shoot is purgative (Husain et al, 1992).

Agrotechnology: Ficus species can be cultivated in rocky areas, unused lands, or other wastelands of the farmyard. The plant is vegetatively propagated by stem cuttings. A few species are also seed propagated. Stem cuttings of pencil thickness taken from the branches are to be kept for rooting. Rooted cuttings are to be transplanted to prepared pits. No regular manuring is required. Irrigation is not a must as a plant is hardy. The plant is not attacked by any serious pests or diseases. Bark can be collected after 15 years. Ficus species generally has an economic life span of more than hundred years. Hence bark can be regularly collected from the tree. Root, bark, leaves, fruits and latex form the economic parts (Prasad et al,1995).... ficus

Alstonia venenata

Apocynaceae

San: Visaghni, Anadana;

Mal: Analivegam;

Tam: Sinnappalai;

Kan: Addasarpa

Importance: Alstonia is a large shrub with straight bole and growing upto about 6m height. The roots are useful in skin diseases, erysipelas, leprosy, cobra bite and other venomous bites, epilepsy, fatigue, fever and otalgia. The fruits are useful in syphilis, insanity and epilepsy. The plant is believed to repel snakes.

Distribution: The plant is distributed throughout India in deciduous forests in areas up to 1800m elevation.

Botany: Alstonia venenata R.Br., belonging to the family Apocynaceae, is a large shrub to small tree up to 6m in height with greyish brown bark and bright yellow hard and woody root. Leaves are simple, arranged in whorls of 3-6, membranous, lanceolate, margins wavy, finely acuminate, main nerves numerous, close, parallel and united by inter marginal nerve. Flowers are white, arranged in terminal sub umbellate cymes or in racemes. Fruits are fusiform with stalked and beaked follicles, tapering at both ends. Seeds are many flattened with a tuft of hair at each end (Warrier et al, 1993). Other important species belonging to the genus Alstonia are the following.

1. A. scholaris R. Br.

This tree is common throughout India. The bark is valuable in debility and after effects of fever, chronic diarrhoea, dysentery and catarrhal fever. The milky juice is applied to ulcers and rheumatic pains, mixed with oil and dropped into ear to relieve earache. Ditanin is the active principle of the bark, possessing powerful febrifuge properties. The bark is astringent, tonic and febrifuge (Nadkarni, 1998).

2. A. spectabilis R. Br.

It is a large evergreen tree seen in tropical forests of Andamans. The bark contains alkaloids such as alstonamine, ditamine, echitamine and echitenine (Chopra et al,1980)

Agrotechnology: The plant is propagated mainly by seeds. Seeds are to be sown on seedbeds and germinated ones are to be transferred to polybags. About three months old seedlings are used for transplanting. If seeds are not available, thin stem cuttings can be planted in polybags and rooted cuttings used. Pits of size 60cm cube are to be taken at 3m spacing, filled with dried cowdung, sand and topsoil and made into a mound. To this mounds seedlings from polybags are to be transplanted. Irrigation is essential during early stages of growth. Application of organic manure every year is beneficial. Regular weeding is to be done. The plant is not attacked by any serious pests or diseases. Flowers are formed in the first year itself. It can be used for medicinal purposes after seven years of growth. Fruits and roots are the economical parts (Prasad et al,1997).

Properties and activity: The plant is a rich source of indole alkaloids. Alkaloids are present in various parts. Stem bark and root contain venenatine, alstovenine, 3-dehydroalstovenine and reserpine. Stem bark contains venoxidine (venenatine Nb -oxide), anhydroalstonatine, kopsinine, venalstonine, venalstonidine(venalstonine-6,7-epoxide), echitovenine and veneserpine. Fruits contain echitovenidine, (+)minovincinine, echitoserpidine, echitoserpine, echitoveniline, 11-methoxy echitovonidine, 11-methoxy (-) minovinicinine, echitoserpiline, (-)vincadifformine, 11-methoxy(-)vincadifformine and venoterpine. Leaves contain echitovenaldine, echitoveniline, alstolenine, deacetylakuammiline, polynuridine, dihydropolynuridine and raucaffrininoline. The yellow tint in bark is because of the presence of 3-alstovenine. A number of indole alkaloids have been further isolated from the plant. In addition to alkaloids fruits contain -amyrin acetate and lupeol ester of -hydroxy acid (Husain et al,1992).

The root is bitter, astringent, thermogenic, depurative, antitoxic, febrifuge and anodyne. The alkaloid alstovenine in lower doses exhibited monoamine oxidase inhibitor activity, while in higher doses it showed marked central stimulant effect. Veninatine exhibited reserpine like activity. Alcoholic extract of the fruits showed initial activation effect on acetylcholine esterase, followed alternately by inhibition and activation of the enzyme.... alstonia

A localised collection of pus. A minute abscess is known as a PUSTULE; a di?used production of pus is known as CELLULITIS or ERYSIPELAS. An abscess may be acute or chronic. An acute abscess is one which develops rapidly within the course of a few days or hours. It is characterised by a de?nite set of symptoms.

Causes The direct cause is various BACTERIA. Sometimes the presence of foreign bodies, such as bullets or splinters, may produce an abscess, but these foreign bodies may remain buried in the tissues without causing any trouble provided that they are not contaminated by bacteria or other micro-organisms.

The micro-organisms most frequently found are staphylococci (see STAPHYLOCOCCUS), and, next to these, streptococci (see STREPTOCOCCUS) – though the latter cause more virulent abscesses. Other abscess-forming organisms are Pseudomonas pyocyanea and Escherichia coli, which live always in the bowels and under certain conditions wander into the surrounding tissues, producing abscesses.

The presence of micro-organisms is not suf?cient in itself to produce suppuration (see IMMUNITY; INFECTION); streptococci can often be found on the skin and in the skin glands of perfectly healthy individuals. Whether they will produce abscesses or not depends upon the virulence of the organism and the individual’s natural resistance.

When bacteria have gained access – for example, to a wound – they rapidly multiply, produce toxins, and cause local dilatation of the blood vessels, slowing of the bloodstream, and exudation of blood corpuscles and ?uid. The LEUCOCYTES, or white corpuscles of the blood, collect around the invaded area and destroy the bacteria either by consuming them (see PHAGOCYTOSIS) or by forming a toxin that kills them. If the body’s local defence mechanisms fail to do this, the abscess will spread and may in severe cases cause generalised infection or SEPTICAEMIA.

Symptoms The classic symptoms of in?ammation are redness, warmth, swelling, pain and fever. The neighbouring lymph nodes may be swollen and tender in an attempt to stop the bacteria spreading to other parts of the body. Infection also causes an increase in the number of leucocytes in the blood (see LEUCOCYTOSIS). Immediately the abscess is opened, or bursts, the pain disappears, the temperature falls rapidly to normal, and healing proceeds. If, however, the abscess discharges into an internal cavity such as the bowel or bladder, it may heal slowly or become chronic, resulting in the patient’s ill-health.

Treatment Most local infections of the skin respond to ANTIBIOTICS. If pus forms, the abscess should be surgically opened and drained.

Abscesses can occur in any tissue in the body, but the principles of treatment are broadly the same: use of an antibiotic and, where appropriate, surgery.... abscess

Burm.

Synonym: A. philippense Linn.

Family: Adiantaceae.

Habitat: Throughout the greater part of India, up to an altitude of 1,200 m.

English: Walking Maidenhair Fern. Black Maidenhair (A. venustum G. Don is also known as Hansaraaja.)

Ayurvedic: Hansapadi, Hansapaadi, Raktapaadi, Kitamaataa, Tri- paadikaa, Hansaraaja; a substitute for Taamrachuda-paadikaa.

Siddha/Tamil: Seruppadai.

Folk: Raajhans, Mubaaraka.

Action: Febrifugal, antidysenteric, soothing agent in erysipelas. The rhizome is also prescribed for strangury, atrophy, emaciation or cachexy, muscular pain; emetic in large doses.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of the dried whole plant in psychosis-related fear. (It is one of the ingredients of the classical drug Maanasamitra Vataka, prescribed for mental disorders.)

The chemical constituents are chlorophyll-degradation products and higher carotenoids.

Dosage: Whole plant-1-3 g (API Vol. III.)... adiantum lunulatum

(Roxb.) Boivin

Family: Mimosaceae.

Habitat: Throughout southern India in dry forests, up to 900 m, and in some parts of Madhya Pradesh.

Ayurvedic: Shirish (bark—grey or greenish).

Siddha/Tamil: Thuringil.

Action: Leaf and flower—anti- inflammatory, used for boils and ulcers. Leaf—used for erysipelas. Seeds—astringent, antidiarrhoeal, antibacterial.

The seed extract showed DNA binding activity, which has been found to be due to pithecolibine alkaloids, bud- munchiamines. Budmunchiamines are antibacterial, and they inhibit platelet aggregation and human lymphocyte transformation. They also show anti-inflammatory and cytotoxic activity.

The leaves contain prodelphinidins, myricitrin, hyperin, quercitrin, trans- p-coumaric acid, cis-p-coumaric acid and trans-ferulic acid.

The seeds contain echinocystic acid and taxifolin-3-O-beta-D xylopyrano- syl-beta-D-arbinopyranoside.

The oil from the seeds is said to cure leprosy and leucoderma.... albizia amara

Ergot poisoning, or ergotism, occasionally results from eating bread made from rye infected with the fungus, Claviceps purpurea. Several terrible epidemics (St Anthony’s Fire), characterised by intense pain and hallucinations, occurred in France and Germany during the Middle Ages (see ERYSIPELAS). Its symptoms are the occurrence of spasmodic muscular contractions, and the gradual production of gangrene in parts like the ?ngers, toes and tips of the ears because of constriction of blood vessels and therefore the blood supply.... ergot poisoning

Linn.

Family: Portulacaceae.

Habitat: Warmer parts of India, cultivated as a vegetable.

Ayurvedic: Laghu-lonikaa.

Siddha/Tamil: Siru Pasalai-keerai.

Action: Similar to P. oleracea. Used in asthma, cough, urinary discharges, inflammations and ulcers. A poultice of the herb is applied to haemorrhoids and erysipelas.... portulaca quadrifida

(L.) Tausch.

Family: Boraginaceae.

Habitat: Cultivated in Central and southern Europe.

English: Alkanet, Dyers' or Spanish Bugloss.

Unani: Ratanjot. National Formulary of Unani Medicine equated Ratanjot with Onosma echioides Linn., found in Kashmir and Kumaon.

Siddha/Tamil: Ratthapaalai, Surul- pattai, Dineshavalli.

Action: Astringent, antimicrobial (used for indolent ulcers, wounds, erysipelas).

The root contains up to 5% alkan- nins, which are lipophilic isohexenyl- naphthazarin red pigments; tannins and wax. A pyrrolizidine (hepatotox- ic) alkaloid has also been isolated from the herb. The alkannins have antimicrobial and wound-healing properties and are non-toxic in mice. They have been used clinically for indolent ulcers.... alkanna tinctoria

Anchusa. Alkanna tinctoria, Tausch. Root. Astringent. Once taken internally as a tea, now externally as an ointment. Antidotes poison in those bitten by venomous snakes, (Dioscorides). Culpeper records its use for St Anthony’s Fire (erysipelas). ... alkanet

A term that means redness of the skin. Disorders in which skin redness is one feature include erythema multiforme, erythema nodosum, erythema ab igne, lupus erythematosus, and erythema infectiosum (also known as fifth disease). Erythema can have many causes, including blushing, hot flushes, sunburn, and inflammatory, infective, or allergic skin conditions such as acne, dermatitis, eczema, erysipelas, rosacea, and urticaria.... erythema

Infections caused by bacteria of the STREPTOCOCCUS group.

A particular type, haemolytic streptococci, can cause tonsillitis, strep throat, scarlet fever, otitis media, pneumonia, erysipelas, and wound infections.

Another type is often responsible for urinary tract infection, and another can cause bacterial endocarditis if it enters the bloodstream.... streptococcal infections

Sw.

Family: Caesalpiniaceae.

Habitat: Cultivated in gardens throughout India.

English: Barbados Pride, Peacock Flower.

Ayurvedic: Padangam, Ratnagandhi, Krishnachuudaa.

Siddha/Tamil: Mayirkonrai, Nalal.

Folk: Guleturaa, Sankeshwara.

Action: Leaves—laxative, antipyretic. Used in Eastern India as a substitute for senna. Dried and powdered leaves are used in erysipelas. Flowers—anthelmintic. Also used for cough and catarrh. Root—a decoction is prescribed in intermittent fevers. Bark— emmenagogue, abortifacient.

The plant contains a flavonoid, my- ricitroside. The leaves, flowers and fruits contain tannins, gums, resin, benzoic acid. Presence of cyanidin- 3,5-diglucoside is also reported from the flowers, hydrocyanic acid from the leaves. The root contains caesalpin type diterpenoids along with sitosterol.

The leaves have displayed anticancer activity in laboratory animals. A diter- penoid, isolated from the root, also showed anticancer activity.

In Pakistan, the leaf and flower extract exhibited activity against Grampositive bacteria.... caesalpinia pulcherrima

Linn.

Family: Sapindaceae.

Habitat: Throughout the plains of India, as a wild climber.

English: Ballon Vine, Winter Cherry, Heartseed.

Ayurvedic: Kaakatiktaa, Kaakaadani, Karnsphotaa, Shatakratulataa.

Unani: Habb-e-Qilqil.

Siddha/Tamil: Mudukottan, Kottavan.

Folk: Kanphotaa, Kanphuti, Lataaphatakari. Used as Jyotishmati in Bengal.

Action: Used in rheumatism, lumbago, skeletal fractures, nervous diseases, amenorrhoea, haemorrhoids, erysipelas. The herb is used in hairoils for treating dandruff, alopecia and for darkening hair.

The plant extract showed significant analgesic and anti-inflammatory activity and sedative effect on CNS. The drug also showed (transient) vasode- pressant activity.

The leaves contain beta-sitosterol and its D-glucoside, an alkaloid, oxalic acid and amino acids. The presence of a saponin and quebrachitol is reported in the plant.

The leaves and stem are used in preparations used against common cold. Alcoholic extract of the plant exhibits antisickling and antiarthritic activity. Seeds have positive anabolic activity and increase body weight by inducing a positive nitrogen balance.

The alkaloid fraction from the seeds showed hypotensive activities and cardiac inhibition in anaesthetized dogs; blocked spasmogenic effects of acetyl- choline, histamine and 5-HT on guinea pig ileum, biphasic effort on frog rec- tus abdominis muscle. The seeds also showed antibacterial activity.

Dosage: Whole plant—50-100 ml decoction. (CCRAS.)... cardiospermum halicacabum

(Linn.) Burm.f.

Family: Rutaceae.

Habitat: Cultivated all over India.

English: Lemon.

Ayurvedic: Jambira, Jambh, Jambhir, Jaamphal, Nimbu, Nimbuka, Naaranga, Limpaka, Dantashatha, Airaavata, Neebu (bigger var.).

Unani: Utraj.

Siddha/Tamil: Periya elumuchhai.

Action: Fruit—antiscorbutic, carminative, stomachic, antihistaminic, antibacterial. Used during coughs, colds, influenza and onset of fever (juice of roasted lemon), hiccoughs, biliousness. Fruit juice—used externally for ringworm (mixed with salt), erysipelas, also in the treatment of leprosy and white spots. Leaves and stems—antibacterial.

All parts of the plants of citrus sp. contain coumarins and psoralins. The fruits contain flavonoids and li- monoids. The flavonoids comprise three main groups—flavanones, fla- vones and 3-hydroxyflavylium (antho- cyanins); flavanones being predominantly followed by flavones and antho- cyanins. Bitter flavonoids do not occur in lemon and lime.

Lemon juice is a richer source of antiscorbutic vitamin (contains 4050 mg/100 g of vitamin C) than lime, and a fair source of carotene and vitamin B1. Volatile oil (about 2.5% of the peel) consists of about 75% limonene, alpha-and beta-pinenes, alpha-ter- pinene and citral. The fruit juice also contains coumarins and bioflavonoids.

The acid content of the fruit, once digested, provides an alkaline effect within the body and is found useful in conditions where acidity is a contributory factor (as in case of rheumatic conditions). The bioflavonoids strengthen the inner lining of blood vessels, especially veins and capillaries, and help counter varicose veins, arteriosclerosis, circulatory disorders and infections of liver, stomach and intestines.

Major flavonoid glycosides, isolated from citrus peels and juices, include hesperidin (with properties of vitamin P). Rutin and other flavanones, isolated from citrus fruits, form the principal components of vitamin P. Flavanone glycosides contained in lemon and lime juices are eriocitrin 47 and 94; hesperidin 84 and 196 mg/l, respectively.

The composition of cold pressed lime oil is quite similar to lemon oil, but citral content of lime oil is higher.

Monoterpene alcohols and their esters, aldehydes—geraniol, geranial and neral, contribute to the characteristic aroma of lemon and lime.

Dosage: Fruit—6-12 g (Juice—5- 10 ml). (API Vol. IV.)... citrus limon

Acacia catechu

Mimosaceae

San:Khadirah;

Hin:Khair, Khaira;

Ben: Kuth;

Mal: Karingali;

Tam: Karunkali;

Tel: Sandra, Khandiramu;

Kan: Kaggali

Importance: Catechu is a medium deciduous tree commonly used as a blood purifier and for leoprosy and leucoderma. Catechu or Cutch tree bark is useful in melancholia, conjunctivitis and haemoptysis. It is useful in vitiated conditions of kapha and pitta, catarrh, cough, pruritus, leprosy, leucoderma, skin diseases, helminthiasis, anorexia, diarrhoea, dysentery, foul ulcers and wounds, haemoptysis, haematemesis, haemorrhages, intermittent fever, inflammations, odontopathy, anaemia, diabetes, splenomegaly and pharyngodyna. The gummy extract of the wood (kath) is useful in laryngopathy, flatulence, anorexia, ulcers, wounds, helminthiasis, leucoderma, leoprosy, skin diseases, urorrhea, colporrhagia, erysipelas and odontopathy. For leprosy, root, leaf, flower, bark and fruits are made into a decoction which is given orally as well as for external dressing. In Unani system it is used in “Marham Kharish Jadid” for skin diseases. “Khadirarisht” is an oral medicine, while “Marham” is for external application.

Distribution:It is widely distributed in tropical countries. In India, it is observed from the Indus eastwards to Assam and throughout Peninsular India.

Botany: The genus Acacia belonging to the family Mimosaceae consists of a number of species. The important ones are listed as below:

A. catechu Willd. A. caesia Willd. A. arabica Willd. A. concinna DC.

A. farnesiana Willd.

A. ferruginea DC.

A. instia W. & A. syn. A. caesia Willd.

A. jacquemontii Benth. A. leucophloea Willd. A. modesta Wall.

A. pinnata (Linn.) Willd.

A. pycnantha Benth.

A. senegal Willd.

A. suma Buch-Ham. syn. A. suma Kurz.

A. catechu is a moderate sized deciduous tree, 9-12m in height with dark greyish or brown rough bark and hooked short spines. Leaves are bipinnately compound, leaflets 30-50 pairs, main rachis pubescent with a large conspicuous gland near the middle of the rachis. Flowers are pale yellow, sessile in peduncled axiallary spikes. Fruits are flat brown pods, shiny and with a triangular beak at the apex and narrowed at the base. Seeds are 3-10 per pod.

The gummy extract of the wood is commercially known as ‘ Kath’ or ‘Cutch’. The cutch available in the market is brittle, of different shapes and dark brown in colour. On breaking, it is found to be shiny and form crystal like pieces (Warrier et al, 1993).

Agrotechnology: Catechu is suited to hilly areas and rocky places. The plant is propagated by seeds.

Seeds are soaked in water for 6 hours and sown in seedbeds. Seeds germinate within a month. At four-leaf stage, seedlings are planted in polybags. Two months old seedlings from the polybags are used for transplanting. Pits of size 50cm cube are taken at a distance of 4-5m between plants and filled with topsoil, sand and dried cowdung in 1:1:1 ratio. Seedlings are planted in these pits. Application of organic manure every year during the rainy season is beneficial. Regular weeding is to be carried out. Pruning of branches and tender shoots developing from the base of the plant can be done from second year onwards. Tree is to be grown as single stemmed one. Flowering and fruiting commences from fourth year onwards. At the end of tenth year, the tree can be cut and heartwood collected (Prasad et al, 1997).

Properties and Activity: Heartwood contains kaempferol, dihydro kaempferol, taxifolin, iso rhamnetin(+)- afzelchin, a dimeric procyanidin, quercetin, (-)epi-catechin, (-)catechin, fisetin, quercetagetin and (+)-cyanidanol. The main constituent of heartwood is catechin and catechu tannic acid. Catechin is a mixture of at least four isomers and L(-)epicatechin has been isolated and characterised (Rao et al,1948; Husain et al,1992).

The bark is anthelmintic, antipyretic, antiinflammatory and antileprotic. The flowers are antigonorrhoeic. The cutch from wood is anthelmintic, tonic and aphrodisiac. Bark and cutch are antidiarrhoeal, astringent and stomachic. Cyanidanol is hepatoprotective. The wood is hypoglycaemic, antiinflammatory and hypotensive. The stem is spasmolytic and antiviral (Husain et al, 1992).... catechu

Stapf.

Synonym: Eragrostis cynosuroides Beauv.

Family: Gramineae; Poaceae.

Habitat: Throughout the plains of India in dry and hot areas and in sandy deserts.

English: Sacrificial Grass (smaller var.)

Ayurvedic: Kusha, Suuchyagra, Yagyabhuushana, Kshurapatra.

Siddha/Tamil: Tharubai.

Action: Root—cooling, diuretic, galactagogue, astringent. Used for urinary calculi, and other diseases of the bladder. Clums—used in menorrhagia, dysentery, diarrhoea and in skin diseases. The Ayurvedic Pharmacopoeia of India recommended the use of the rootstock in dysuria, vaginal discharges and erysipelas.

Dosage: Rootstock—50-100 g for decoction. (API Vol. III.)... desmostachya bipinnata

Linn.

Family: Moraceae.

Habitat: Sub-Himalayan tract and Peninsular India. Planted along roadsides, and in gardens.

English: Banyan tree.

Ayurvedic: Vata, Nyagrodha, Bahupaada, Dhruv.

Unani: Bargad, Darakht-e-Reesh.

Siddha/Tamil: Aalamaram.

Action: Infusion of bark—used in diabetes, dysentery, and in seminal weakness, leucorrhoea, menorrhagia, nervous disorders, erysipelas, burning sensation. Milky juice and seeds—applied topically to sores, ulcers, cracked soles of the feet, rheumatic inflammations. Buds—a decoction in milk is given in haemorrhages. Aerial roots— antiemetic, topically applied to pimples. Leaves—a paste is applied externally to abscesses and wounds for promoting suppuration.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India recommends the aerial root in lipid disorders.

Phytosterolin, isolated from the roots, given orally to fasting rabbits at a dose of 25 mg/kg, produced maximum fall in blood sugar level equivalent to 81% of the tolbutamide standard after 4 h. The root bark showed antidiabetic activity in pituitary diabetes and alloxan-induced diabetes.

The alcoholic extract of the stem bark also exhibited antidiabetic activity on alloxan-induced diabetes in albino rats, and brought down the level of serum cholesterol and blood urea. This activity is attributed to a glucoside, bengalenoside and the flavonoid glycosides, leucocyanidin and leucopelargonidin. Bengalenoside is half as potent as tolbutamide. The leucopelargonidin glycoside is practically nontoxic and may be useful in controlling diabetes with hyperlipi- demia. The leucocyanidin, when combined with a low dose of insulin, not only equalled in response the effects brought about by a double dose of insulin, but also excelled in amelioration of serum cholesterol and triglycerides.

(Additional references: Indian J Physiol Pharmacol, 1975, 19(4), 218220; J Ethnopharmacol, 1989, 26(1), 155; Indian J Physiol Pharmacol, 1994, 38(3), 220-222.)... ficus benghalensis

Buch.-Ham.

Synonym: F. infectoria auct. non- Willd.

F. viren Aiton.

Family: Moraceae.

Habitat: Plains and lower hills of India.

English: White Fig.

Ayurvedic: Plaksha, Karpari, Pitana, Parkati.

Siddha/Tamil: Kurugu, Itthi, Kallalnaram.

Action: Bark—decoction is used for washing ulcers, as a gargle in salivation; also used for menstrual disorders and leucorrhoea. Leaf— estrogenic. Plant— used in erysipelas, ulcer, epistaxis.

Fresh ripe fruit or powder of dried fruits is used to treat diabetes.

The Ayurvedic Pharmacopoeia ofIn- dia indicates the use of the fruit and stem bark in syncope, delirium and illusive and unstable state of mind. The stem bark of the plant yield acetates of long-chain alcohols, methyl- ricinolate, beta-sitosterol, lanosterol, caffeic acid, bergenin and sugars. The triterpenoids, lupeol and alpha- and beta-amyrin, are also present in the leaves. Flavonoids including sorbifolin and scutellarein derivatives, have been isolated from the leaves.

Dosage: Stem bark—50 g powder for decoction (API Vol. II); dried fruit—5-10 g. (API Vol. IV.) Leaf, root—10-20 g paste. (CCRAS.)... ficus lacor

(L.) DC.

Synonym: G. nudicaulis Arn.

Family: Asteraceae, Compositae.

Habitat: Eastern Himalaya, Sikkim, Assam, and Western Ghats in Tamil Nadu and Kerala.

Action: Plant—emollient, resolvent. Used as a poultice in erysipelas and for tumours in the breast. Root—used both externally and internally for enhancing blood circulation especially when blue spots and blotches result from blows. The powdered root, mixed with tea, is given to parturient women. Leaves—used for poulticing pimples. The juice is used asa gargle for inflammations of the throat.... gynura pseudo-china

Vahl ex DC.

Family: Fabaceae.

Habitat: Plains of Karnataka, Andhra Pradesh and Tamil Nadu.

English: Wiry Indigo.

Ayurvedic: Nili (related species), Shivanimba.

Siddha/Tamil: Sivanaarvembu, Iraivanvembu.

Folk: Shivanimba (Maharashtra).

Action: Antileprotic, antitumour, anti-inflammatory. Used in psoriasis and erysipelas. Ash of the burnt plant is used for dandruff. Root is used in aphthae.... indigofera aspalathoides

DC.

Synonym: N. grandiflora DC.

Family: Valerianaceae.

Habitat: Alpine Himalayas, Kumaon, Sikkim and Bhutan.

English: Spikenard, Musk-root.

Ayurvedic: Maansi, Jataamaansi, Bhuutajataa, Tapaswini, Sulo- mashaa, Jatilaa, Naladaa.

Unani: Sumbul-e-Hindi, Sambul-ut- Teeb, Naardeen-e-Hindi, Baalchhar.

Siddha/Tamil: Sadamanchil.

Action: Used as a substitute for Valerian. Tranquilizer, sedative, hypotensive. Used for the treatment of epilepsy, hysteria, convulsive affections, palpitation of heart and in intestinal colic. A decoction of powdered roots is prescribed as a home remedy for high blood pressure. It is used in dysmenorrhoea for pain relief and smooth menstrual flow. It is used in hair oil for arresting hair loss and greying of hair.

The Ayurvedic Pharmacopoeia of India recommends dry rhizomes in obstinate skin diseases, erysipelas, disturbed mental state and insomnia.

The rhizome is rich in sesquiter- penoids. The crude drug gave an oil (yield 2.5% v/w), which contains d- nardostachone, valeranone and jata- mansone as the major ketonic sesqui- terpenes. The oil potentiated phenobarbital narcosis in rats, reduced brain serotonin content and decreased the conditioned avoidance performance in cats.

Jatamansone was shown to exert tranquilizing effect in mice and monkeys. In rabbits, jatamansone was found to impair biosynthesis of serotonin in the brain leading to a reduction in brain level of 5-hydroxytrypta- mine. The degradation of serotonin was unaffected. The mode of action of jatamansone was thus in variance with that of reserpine which has direct action on the cell to liberate serotonin.

On the other hand, the alcoholic extract of the roots of Indian Nard caused an overall increase in the levels of central monamines, 5-hydroxy indole acetic acid and the inhibitory amino acids, gamma-aminobutyric acid, norepinephrine, dopamine and serotonin in rat brain.

In a clinical trial on hyperkinetic children, jatamansone showed significant reduction in hyperactivity and improvement in restlessness and aggressiveness, almost at par with D- amphetamine.

The volatile oil was found to be less active than quinidine in several tests. It did not counteract digitalis induced ventricular arrhythmias.

Jatamansone semicarbazone, a sesquiterpene ketone, was found to possess antiestrogenic activity.

N. jatamansi is also used in place of Muraa (Selinum tenuifolium Wall. ex DC.)

Dosage: Root—2-3 g powder; 5-10 g for infusion; 50-100 ml infusion. (API, Vol. I; CCRAS.)... nardostachys jatamansi

Linn.

Family: Portulacaceae.

Habitat: All over India, cultivated as a vegetable.

English: Common Purslane.

Ayurvedic: Brihat Lonikaa, Lonaa, Loni, Ghoddhika, Ghotikaa, Upodika, Khursaa.

Unani: Khurfaa, Kulfaa.

Siddha/Tamil: Pulli-keerai, Parup- pukirai.

Action: Refrigerant (reduces body heat), mild spasmodic, diuretic, antiscorbutic. Used in scurvy and in diseases of liver, spleen, kidney and bladder; also in dysuria, stomatitis and dysentery. A paste of leaves is applied to swellings, erysipelas, burns and scalds. Seeds—diuretic, antidysenteric; applied externally to burns and scalds.

A crude protein-free extract of the herb contained l-nor-adrenaline, do- pamine and l-dopa, also catechol. (The fresh plant contained 2.5 mg/g l-nor- adrenaline in one sample.) The extract gave a strong pressor response when injected intravenously into anaesthetized dogs.

The oral administration of the ho- mogenates of P. oleracea reduced the blood sugar level of alloxan-diabetic rabbits to normal.

The extract of the leaves and stems reduced muscle tone in individuals suffering from spasticity and exhibited skeletal muscle relaxant activity both in vitro and in vivo. The extract produced dose-dependent negative in- otropic and chronotropic effects and pressor response on rat blood pressure.

The diuretic action of the herb is attributed to the presence of high percentage of potassium salts.

Dosage: Plant-125-400 mg powder; juice—1-20 ml (CCRAS.)... portulaca oleracea

Certain skin diseases – particularly CHILBLAIN, ACNE, LUPUS and ERYSIPELAS – tend to affect the NOSE, and may be very annoying. Redness of the skin may be caused by poor circulation in cold weather.

Acute in?ammation is generally the result of a viral infection (see COLD, COMMON) affecting the mucous membrane and paranasal sinuses (see SINUSITIS); less commonly it results from the inhalation of irritant gases. Boils may develop just inside the entrance to the nose, causing pain; these are potentially troublesome as infection can spread to the sinuses. HAY FEVER is one distressing form of acute rhinitis.

Malformations are of various kinds. Racial and familial variations in the external nose occur and may be a reason for RHINOPLASTY. Di?erences in the size and shape of the nose occur, often forming the starting point for chronic in?ammation of the nose, perennial rhinitis (all the year round), hay fever, or ASTHMA. More commonly, obstruction results from nasal polyps or adenoids, leading to inhalation through the mouth. Adenoids are an overgrowth of glandular tissue at the back of the throat, into which the nose opens. Polyps are growths of soft jelly-like character: they arise from chronic in?ammation associated with allergic rhinitis, chronic sinusitis, asthma, and aspirin abuse. Large polyps can cause erosion of the nasal bones and should be surgically removed.

Bleeding (see HAEMORRHAGE).

Foreign bodies At ?rst these may not cause any symptoms, but in time they can cause obstruction of the affected nostril with a foul-smelling bloody discharge. The problem is common with small children who tend to push small objects into their noses. Foreign bodies require removal, sometimes in hospital. Anyone attempting to remove a foreign body should take care not to push it further into the nose.

Loss of sense of smell, or anosmia, may be temporary or permanent. Temporary anosmia is caused by conditions of the nose which are reversible, whereas permanent

anosmia is caused by conditions which destroy the OLFACTORY NERVES. Temporary conditions are those such as the common cold, or other in?ammatory conditions of the nasal mucosa or the presence of nasal polyps (see above). Permanent anosmia may follow in?uenzal NEURITIS or it may also follow injuries to the brain and fractures of the skull involving the olfactory nerves.

Injury to nose The commonest injury is a fracture of the nasal bones or displacement of the cartilage that forms the bridge of the nose. The nasal SEPTUM may also be displaced sideways by a lateral blow. Sporting activities, especially boxing and rugby football, are commonly a cause of nasal injury. If a fracture is suspected, or if there is substantial tissue swelling, an X-ray examination is necessary. Resetting a damaged bone should be done either immediately, before swelling makes surgery di?cult, or ten days or so later when the swelling has subsided. Results are usually good, ensuring a clear airway as well as a restored pro?le. It is not unusual for the cheek-bone to sustain a depressed fracture at the same time as the nose is broken. Careful assessment and prompt surgery are called for. (For more information on fractures, see under BONE, DISORDERS OF).

Rhinitis In?ammation of the MUCOUS MEMBRANE lining the nose. Symptoms include nasal discharge and obstruction, sneezing and sometimes pain in the sinuses. There are several types of rhinitis:

•Allergic – due to allergy to dust, pollen or other airborne particles. Also called hay fever, allergic rhinitis causes a runny nose, sneezing and local congestion. It affects up to 10 per cent of the population and is more common in people suffering from other allergic disorders such as asthma or eczema (see DERMATITIS). Skin tests help to identify the causative ALLERGEN which the sufferer can then try to avoid, although in the case of pollen this is di?cult. Decongestant drugs, ANTIHISTAMINE DRUGS, and CORTICOSTEROIDS may help, as can SODIUM CROMOGLYCATE inhaled regularly during the pollen season. A desensitisation course to a particular allergen sometimes provides long-term relief.

Atrophic rhinitis is caused by a deterioration in the nasal mucous membrane as a result of chronic bacterial infection, nasal surgery or AGEING. Symptoms include persistent nasal infection and discharge and loss of sense of smell. ANTIBIOTICS and, in some cases, OESTROGENS alleviate the symptoms.

Hypertrophic rhinitis results from repeated nasal infection, and is characterised by thickened nasal membranes and congestion of the nasal veins. Removal of thickened mucosa may help severe cases.

Vasomotor rhinitis occurs when the mucosa becomes oversensitive to stimuli such as pollutants, temperature changes or certain foods or medicines. It may occur as a result of emotional disturbances and is common in pregnancy.

Viral rhinitis occurs as a result of infection by the common cold virus; treatment is symptomatic. Sinusitis is sometimes a complication.... nose, disorders of

Roxb.

Synonym: P. pilosa Linn.

Family: Portulacaceae.

Habitat: Peninsular India, near sea-coasts.

Ayurvedic: Bichhuu-buuti.

Folk: Jangali Gaajar (Gujarat), Sanjivani (Bihar).

Action: Leaves—an infusion is given internally in dysuria; externally applied to erysipelas. The herb shows diuretic, calculolythic, analgesic and antipyretic properties.

The aerial parts contain diterpe- noids, pilosanone A and B. leucorrhoea, dysmenorrhoea, arthritis, cramps, kidney stones, bleeding piles; as a mouth wash in pyrrhoea, gingivitis and sore throat.

Key application: In mild dismenor- rhoeal disorders; as a support for treatment of milder, nonspecific, acute diarrhoea and in light inflammation of the oral and pharyngeal mucosa. (German Commission E.)

The plant gave anthocyanins—cy- anidin and delphinidin. Aerial parts gave tannins (2-10%). The plant also gave choline, betaine, histidine, an essential oil and vitamin E.

The maximum amounts of tannins occur in the root stock (up to 17.5% on dry basis). The ethanolic and aqueous extract of the herb (1 : 5) contain 0.3 to 0.8% of tannin. The tannin fraction exhibited anti-mutagenic effect.

Potentilla fruticosa HK. (temperate Himalaya) is also used like Silverweed.

The flowers and young shoots contain flavonoids, quercetin, terniflorin, tribuloside and (-)-catechin. The plant also contains stigmasterol, beta-sitos- terol and campesterol; (-)-epicatechol gallate, (±)-catechol, (-)-epicatechol, (-)-epigallocatechol and (-)-epigallo- catechol gallate have been isolated from aerial parts.... portulaca tuberosa

Linn.

Family: Rosaceae.

Habitat: Native of Eurasia; cultivated in Kashmir, Himachal Pradesh and Kumaon for edible fruits.

English: Sour Cherry.

Ayurvedic: Elavaaluka (var.).

Folk: Aalu-baalu, Gilaas.

Action: Fruit—diuretic, anti- inflammatory. Used for genitourinary inflammations, cystitis and urine retention. Bark—febrifuge, antidiarrhoeal. Fruit stalk—diuretic. Fruit stalk and stem—pectoral. Bark and fruit stalk—astringent. Kernel—nervine. Leaf—an infusion is given for convulsions in children.

Key application: Heartwood—in skin eruptions, erysipelas, obstinate skin diseases, haemorrhagic diseases. As a tonic for promoting conception. (The Ayurvedic Pharmacopoeia of India.)

The leaves, fruits and bark gave flavone glycosides. The bark contains 5-7% tannin. The kernel contains a considerable proportion of hydrocyanic acid. The leaves contain amyg- dalin. (Amygdalin, a nitrile glycoside, has been reported to inhibit the growth of Sarcoma-180 cells in culture.)... prunus cerasus

Nooteboom.

Synonym: Samadera indica Gaertn. S. indica var. lucida Blatter. S. lucida Wall.

Family: Simaroubaceae.

Habitat: West Coast, along back waters and evergreen forests from Maharashtra southwards to Trivandrum.

English: Niepa Bark tree.

Siddha/Tamil: Nibam, Niepa, Karinjottei.

Folk: Lokhandi (Maharashtra).

Action: Bark—febrifuge; juice applied to skin diseases. An infusion of wood and bark is given as emmenagogue. Seed— emetic, purgative; used for bilious fevers. Seed oil—applied in rheumatism. Leaves— externally in erysipelas.

The bark contains the quassinoids, indaquassin, A, D, E and F; samader- ine B to E, dihydrosamaderine B, brucein D, soulameolide, cedronin and canthin-2, 6-dione.

Brucin D showed activity against Walker's carcinoma. Samaderine E, isolated from the plant, exhibits anti- leukaemic activity.... quassia indica

Linn.

Synonym: R. munjesta Roxb.

Family: Rubiaceae.

Habitat: Throughout India, ascending to an altitude of 3,700 m.

English: Indian Madder, Bengal Madder.

Ayurvedic: Manjishthaa, Vikasaa, Samangaa, Yojanavalli, Kaalameshi- ka, Raktaangi, Raktayashtikaa, Arunaa, Gandira, Jingi.

Unani: Manjeeth.

Siddha/Tamil: Manjitti.

Action: Roots and dried stem— blood purifier, astringent, diuretic, emmenagogue, deobstruent, antidysenteric, antiseptic, alterative.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the use of the dried stem in blood, skin and urinogenital disorders; dysentery; piles, ulcers, inflammations; erysipelas, skin diseases and rheumatism. (Roots, leaves and seeds of R. cordifolia, R. tinctorum and allied species are used in amenorrhoea, liver diseases, gall and spleen complaints.) (Mutagenic and carcinogenic aspects of the drug are under investigation.)

It is reported that after oral administration of the root decoction, the urine and bones of the patient show a red tinge.

The roots are rich in anthraquinones and their glycosides (around 20), the important ones include purpurin (tri- hydroxy anthraquinone), munjistin (xanthopurpurin-2-carboxylic acid); besides xanthopurpurin, peudopur- purin (purpurin-3-carboxylic acid), free alizarin as well as its glucoside.

Whole plant yielded pentacylic tri- terpenic acids—rubicoumaric and ru- bifolic acids.

Antitumour cyclic hexapeptides have been isolated from the root (while lucidin is thought to be carcinogenic).

The root extracts of R. sikkimensis Kurz, known as Naaga-Madder (Nepal eastwards to Assam, Nagaland and Ma- nipur); are very similar to those of R. cordifolia.

Dosage: Stem—2-4 g. (API, Vol. III.)... rubia cordifolia

Roxb.

Synonym: S. sara Roxb. S. bengalense Retz. Erianthus munja Jesw.

Family: Gramineae; Poaceae.

Habitat: Throughout the plains and low hills of India.

Ayurvedic: Munja, Bhadramuja, Vaana, Shara, Sara, Raamshara.

Siddha/Tamil: Munjipul, Munjap- pullu.

Folk: Sarpata.

Action: Refrigerant. Useful in burning sensation, thirst, dyscrasia, erysipelas and urinary complaints.

The Ayurvedic Pharmacopoeia of India recommends the use of the root in dysuria, giddiness and vertigo.

The stem is a good source of furfural (yield 5.67%, dry basis). It yields 19.5% (on dry weight) of reducing sugars when digested with sulphuric acid; glucose, xylose, galactose and rhamnose have been identified in the hydrolysate which contains 34.5% fermentable sugars. (It can be used as a potential source of alcohol.)

In Kerala, Saccharum arundinaceum Retz. is used as Shara for dysuria, diseases due to vitiated blood, erysipelas, leucorrhoea and piles. The grass is known as Raamshara in North India. It can also be used for the production of furfural (yield 5.1% dry basis) and yields 24.1% of reducing sugars when digested with sulphuric acid. The hy- drolysate contains 65% of fermentable sugars, viz. glucose, xylose, galactose and rhamnose.

Dosage: Root—20-50 g for decoction; 6-10 g powder. (API, Vol. III.)... saccharum munja

W. & A.

Synonym: T. alata Heyne ex Roth.

Family: Combretaceae.

Habitat: Common in the forests, especially in the humid regions of India, including the sub-Himalayan tracts of North-West provinces, Nepal and Sikkim; also southwards throughout the Peninsula.

English: Laurel (trade). (The Wealth of India.)

Ayurvedic: Asana (Asana is equated with Bridelia montana Willd.) Bijaka (also equated with Pterocarpus marsupium Roxb.) (Asana and Bijaka are considered as synonyms in Indian medicine.) Jaranadrum, a substitute of Ashwakarna, and Kaushik are also doubtful synonyms.

Siddha/Tamil: Karramarda.

Folk: Sarj, Saaj. Sain (Dehra Dun).

Action: Bark—astringent, antidiar- rhoeal, styptic, antileucorrheal. Used for haemorrhagic diseases, skin diseases, erysipelas, leuco- derma. The bark contain 18.7% tannin.

Beta-sitosterol, arjunic and arjuno- lic acids, arjunetin, betulinic and el- lagic acids have been isolated from the bark.

Hydrolysis of gum gave oligo-sac- charides, disaccharides and monosac- charides. Leaves and fruits gave beta- sitosterol.

Laurel is native to Mediterranean region and is equated with Laurus nobilis Linn. (Lauraceae.) The leaves and essential oil are stomachic, cholagogue, stimulant and diaphoretic. The oil has been used against dandruff, also as an external application for rheumatism.... terminalia tomentosa

(Decne) Sch.-Bip.

Synonym: S. costus (Falc.) Lipsch.

Family: Compositae; Asteraceae.

Habitat: Kashmir, Himachal Pradesh and Garhwal at 25003,000 m; cultivated in Kashmir and neighbouring regions.

English: Kuth, Costus.

Ayurvedic: Kushtha, Kusht, Vaapya, Kaashmira, Gada, Rug, Ruk, Aamaya, Paalaka. (Substitute: Pushkara Muula, Inula racemosa.)

Unani: Qust.

Siddha/Tamil: Kostum, Kottam.

Folk: Sugandha-Kuutth.

Action: Root—antispasmodic, expectorant, carminative, astringent, antiseptic. An ingredient of prescriptions for dyspepsia, asthma, cough, chronic rheumatism, skin diseases. Applied locally to wounds and ulcerations. Powdered root, mixed with mustard oil, is applied to scalp in prurigo.

The Ayurvedic Pharmacopoeia of India recommends the root in cough, bronchitis, dyspnoea; erysipelas and gout.

The root (containing both the essential oil and alkaloid, saussurine) is used for asthma, particularly of vagotonic type. It produces a definite relaxtion of the bronchioles. The relief obtained is comparable to that of conventional bronchodilators without side effects, like a rise in blood pressure, sweating or headache even on repeated administration.

Saussurine depresses parasympa- thetic nervous system. The aminoacid- sesquiterpene adducts, saussureami- nes A, B and C show antiulcer effect. The aqueous extract of the root exhibits antianginal activity.

Essential oil inhibits peristalic movement of the gut. It is absorbed from the gastro-intestinal tract and partly excreted by lungs producing an expectorant action and partly by the kidneys producing diuretic effect. (In Western herbal, Kuth essential oil is not prescribed internally.)

Kuth roots contain resinoids (6%), and essential oil (1.5%), alkaloid (0.05%) inulin (18%), saussurea lactone (20-25%), a fixed oil and minor constituents like tannin and sugars. Roots obtained from Kashmir are, in general, richer in essential oil content than roots obtained from Garhwal and Nepal. The roots of Punjab variety gave cos- tunolide, dehydrocostuslactone, costic acid, palmitic and linoleic acids, beta- sitosterol and alpha-cyclocostunolide. The Kashmir variety, in addition, gave alantolactone, beta-cyclocostunolide and iso-alantolactone.

The essential oil of the roots exhibit strong antiseptic and disinfectant activity against Streptococcus and Staphy- lococcus.

Costus speciosus Sm. synonym Banksea speciosa, also known as Kush- tha, is a different herb of Zingiberaceae family. Rhizomes and stems yield dios- genin.

Dosage: Root—0.2-1.0 g powder. (API, Vol. I.)... saussurea lappa

Skin eruption resembling dermatitis or urticaria. A contact allergy from plants such as poison ivy and primula, various chemicals (red-headed matches), cosmetics (make-up), nail varnish, after-shave, certain drugs and perfumes. Allergic reactions are associated with swollen eyelids, shingles, erysipelas or sinus infections. Fever sometimes present and lesions may take the form of the weals of nettle-rash. A hereditary form is rare but the condition is a frequent reaction to aspirin. Differentiate from eczema.

Alternatives. Tea. Formula. Equal parts: Red Clover flower, Nettles, Clivers. 2 teaspoons to each cup boiling water; infuse 10-15 minutes. 1 cup 2-3 times daily.

Tablets/capsules. Garlic. Echinacea. Blue Flag root. Poke root.

Powders. Formula. Echinacea 2; Juniper 1; Blue Flag root half. Dose: 500mg (two 00 capsules or one- third teaspoon) 2-3 times daily before meals.

Tinctures. Formula. Echinacea 2; Valerian 1; Blue Flag root half. Dose: 1-2 teaspoons in water 2-3 times daily before meals. ... angio-oedema

Bullock’s eye. Sempervivum tectorum L. German: Hauswurz. French: Joubarbe. Spanish: Siempreviva. Italian: Sempervivo dei tette. Chinese: Ching-t’un. Plant thrives on roof tiles. Fresh leaves.

Constituents: malic acid, lime salts, tannin, mucilage.

Action: anti-inflammatory, astringent, analgesic (mild), refrigerant.

Uses: Long European reputation for scirrhous induration of the tongue, burning skin rashes, urticaria, nettle stings, and chronic mouth ulcers. Galen advised juice of fresh leaves to dispel pain of shingles and erysipelas. Dioscorides mentions its use for weak and inflamed eyes (eye-drops). Injected into the ear for relief of earache. Wiped over the forehead, juice from the fresh leaf may relieve migraine and chronic headache. Has been used with success for cancer of the breast, tongue and cervix.

Preparations: Has a better record of success from use of the fresh leaf than by alcohol.

German traditional: mix juice with equal volume of fresh cream.

Poultice: bruised fresh leaves for inflamed skin, shingles, etc.

Much neglected agent. ... houseleek

They may be local to the SKIN, or a manifestation of systemic disorders – inherited or acquired. Some major types are described below.

Others appear under their appropriate alphabetical headings: ACNE; ALBINISM; ALOPECIA; ALOPECIA AREATA; APHTHOUS ULCER; BASAL CELL CARCINOMA; BOILS (FURUNCULOSIS); BOWEN’S DISEASE; CALLOSITIES; CANDIDA; CHEILOSIS; CHEIRAPOMPHOLYX; DANDRUFF; DERMATOFIBROMA; DERMATOMYOSITIS; DERMATOPHYTES; DERMOGRAPHISM; ECTHYMA; ERYSIPELAS; ERYTHEMA; ERYTHRASMA; ERYTHRODERMA; ESCHAR; EXANTHEM; FUNGAL AND YEAST INFECTIONS; HAND, FOOT AND MOUTH DISEASE; HERPES GENITALIS; HERPES SIMPLEX; HERPES ZOSTER; IMPETIGO; INTERTRIGO; KELOID; KERATOSIS; LARVA MIGRANS; LICHEN; LUPUS; MADURA FOOT; MELANOMA; MILIARIA; MOLLUSCUM CONTAGIOSUM; MOLE; MYCOSIS FUNGOIDES; NAEVUS; ORF; PEDICULOSIS; PEMPHIGUS; PHOTOCHEMOTHERAPY; PHOTODERMATOSES; PITYRIASIS; PORPHYRIAS; PRURITUS; PSORIASIS; RINGWORM; ROSACEA; SARCOIDOSIS; SCABIES; SCLERODERMA; URTICARIA; VITILIGO; WARTS; XANTHOMATA.

Skin cancer Primary cancer is common and chronic exposure to ultraviolet light is the most important cause. BASAL CELL CARCINOMA is the most common form; squamous cell carcinoma is less common and presents as a growing, usually painless nodule which may ulcerate. Squamous cancer may spread to regional lymph glands and metastasise, unlike basal cell cancer. Occupational exposure to chemical carcinogens may cause squamous carcinoma – for example, cancer from pitch warts or the scrotal carcinoma of chimney sweeps exposed to coal dust in earlier centuries. Squamous carcinoma of the lip is associated with clay-pipe smoking.

Cancer may arise from the population of melanocytes of the skin (see MELANOCYTE; MELANOMA).

Apart from these three most frequent forms of skin cancer, various forms of cancer can arise from cells of the dermis, of which LYMPHOMA is the most important (see also MYCOSIS FUNGOIDES).

Lastly, secondary deposits from internal cancer, particularly from the breast, may metastasise to the skin.

Dermatitis and eczema These are broadly synonymous, and the terms are frequently interchangeable. Eczema is a pattern of in?ammation with many potential causes. Dermatitis is commonly used to suggest an eczema caused by external factors; it is a common pattern of in?ammation of the skin characterised by redness and swelling, vesiculation (see VESICLE), and scaling with intense itching and often exudation (weeping). Fissuring, thickening (licheni?cation – see LICHEN) and secondary bacterial infection may follow. Dermatitis can affect any part of the body. It may be genetically detemined or due to other ‘internal’ factors, such as venous HYPERTENSION in a leg, or stress. Often it is ‘external’ in origin – due to strong irritants or chemical allergens. (See also ALLERGY; ALLERGEN.) ATOPIC DERMATITIS is genetic in origin and usually begins in infancy. It may persist for years, and ASTHMA, allergic RHINITIS and conjunctivitis (see under EYE, DISORDERS OF) – ‘hay fever’ – may be associated. Atopic children tend to have multiple allergies, especially to inhaled allergens such as house-dust mite, cat and dog dander and pollens. Allergy to foods is less common but potentially more dangerous, especially if to nuts, when it can cause acute URTICARIA or even ANAPHYLAXIS. Atopic subjects are particularly prone to persistent and multiple verrucae (see WARTS) and mollusca (see MOLLUSCUM CONTAGIOSUM) and to severe HERPES SIMPLEX infections. (See also ATOPY.)

EXFOLIATE DERMATITIS (PITYRIASIS RUBRA)

Generalised exfoliation and scaling of the skin, commonly with ERYTHEMA. Drugs may cause it, or the disorder may be linked with other skin diseases such as benign dermatoses and lupus erythematosus (see under LUPUS). SUMMER POMPHOLYX is an acute vesicular eczema of the palms and soles recurring every summer. Inhaled allergens are a frequent cause. VENOUS (STASIS) DERMATITIS begins on a lower calf, often in association with PURPURA, swelling and sometimes ulceration. Chronic venous hypertension in the leg, consequent on valvular incompetence in the deep leg veins owing to previous deep vein thrombosis (see VEINS, DISEASES OF), is the usual cause. NEURODERMATITIS A pattern of well-de?ned plaques of licheni?ed eczema particularly seen on the neck, ulnar forearms or sides of the calves in subjects under emotional stress. IRRITANT CONTACT DERMATITIS Most often seen in an industrial setting (occupational dermatitis), it is due to damage by strong chemicals such as cutting oils, cement, detergents and solvents. In almost all cases the hands are most severely affected. ALLERGIC CONTACT DERMATITIS, in contrast, can affect any part of the body depending on the cause – for example, the face (cosmetics), hands (plants, occupational allergens) or soles (rubber boots). Particularly common allergens include metals (nickel and chromate), rubber addititives, and adhesives (epoxy resins).

Treatment Avoidance of irritants and contact allergens, liberal use of EMOLLIENTS, and topical application of corticosteroid creams and ointments (see CORTICOSTEROIDS) are central.... skin, diseases of

Kurz.

Synonym: W. floribunda Salisb.

Family: Lythraceae.

Habitat: Throughout North India, rather scarce in South India.

English: Fire-flame Bush, Shiran- jitea.

Ayurvedic: Dhaataki, Dhaatri, Kun- jaraa, Taamrapushpi, Bahupushpi, Vahnijwaalaa.

Siddha/Tamil: Velakkai.

Action: Dried flower—purifies blood, heals ulcers, astringent, prescribed in haemetemesis, erysipelas, dysentery, diarrhoea, menorrhagia, leucorrhoea. Flowers are used in alcohol-based tonics for fermentation (a yeast strain, saccharomyces cerevisiae, has been isolated). Bark—uterine sedative.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the flower in acute diarrhoea, haemorrhages, ulcerations and erysipelas.

The dried flowers are powdered and sprinkled over ulcers and wounds. The flowers also enter into an ointment used on pustules of smallpox.

In small doses the plant stimulates, while in large doses depresses the central nervous system.

The flowers and leaves gave polyphe- nols—ellagic acid, polystachoside and myricetin-3-galactoside. Flowers also gave anthocyanins—pelargonidin- 3,5-diglucoside and cyanidin-3,5-di- glucoside; octacosanol, chrysopha- nol-8-O-beta-D-glucopyranoside and beta-sitosterol. Hecogenin, mesoinos- itol and flavone glycosides—quercetin- 3-rhamnoside, naringenin-7-glucoside and kaempferol, have been reported from flowers.

The bark contains C-glucoside, ber- genin.

The flowers, leaves and bark contain tannins—24.1, 12-20 and 20-27% respectively. Dimeric hydrolyzable tannins—woodfordins A, B and C, and trimeric tannins woodfordin D and oenothein A and B have been isoalt- ed from dried flowers. A new tannin monomer, isoschimawalin A and five oligomers—woodfordin E, F, G, H and I, have also been isoalted.

Oenothein A and B exhibited remarkable host-mediated antitumour activity. Woodfordin C and D also showed antitumour activity. Woodfordin C showed inhibitory activity toward DNA topoisomerase II.

Dosage: Flower—3-6 g powder. (API, Vol. I.)

English: Pala Indigo Plant.

Ayurvedic: Shveta Kutaja. (white- flowered), Punkutaja, Indrayava (seeds).

Unani: Inderjao Shireen.

Siddha/Tamil: Irum-paalai, Nila- paalai.

Action: Bark—antidysenteric. Also used in piles and skin diseases. Seeds—antidysenteric, astringent, febrifuge, anthelmintic. Bark and seeds—prescribed in flatulence and bilious affections.

Pods, without seeds, contain the cycloartanes, cycloartenone and cy- cloeucalenol along with alpha- and beta-amyrin, beta-sitosterol, ursolic acid, oleanolic acid and the terpene, wrightial. The leaves contain beta- amyrin. Stem bark gave beta-amyrin, beta-sitosterol and lupeol.

The seeds, leaves and roots have been shown to contain an indigo- yielding glucoside.

The flowers gave 3-O-rhamnogluco- side which exhibited significant anti- inflammatory activity in carrageenan- induced hind paw oedema.

The bark is commonly used as an adulterant of Kurchi Bark (obtained from Holarrhena antidysenterica).... woodfordia fruticosa

Citrus limonum. Refreshing and fragrant essential oil.

Constituents: flavonoids, coumarins, mucilage, Vitamin C, calcium oxalate.

Action: prevention and treatment of scurvy, anti-infective, anti-inflammatory, anti-fat, antihistamine.

Contains citric acid which is an anti-bacterial capable of destroying some viruses and bacteria.

Uses: Coughs, colds, influenza and onset of fevers generally. Traditionally a whole lemon was roasted or baked in a moderate oven for half an hour and as much juice drunk as tolerated. Sore throat (gargle). Diphtheria: impressive cures reported. Persist until false membrane is detached: Neat lemon juice gargle hourly, swallowing 1-2 teaspoons. If too strong, may be diluted. Often overlooked for hiccoughs. Dropsy: lemon fast. 3-4 days on lemon juice alone: no solid food, tea, stimulants, etc. Biliousness, sick headache: juice of a lemon morning and evening; sweeten with honey if necessary. Malaria: half a teacup juice in water every 2-3 hours. Rheumatism: juice of half lemon before meals and at bedtime; may be diluted. For rheumatism, anecdotal success has been reported by combining equal parts lemon juice and molasses: tablespoon thrice daily before meals. Cellulitis. A lemon mask helps to fade spots.

External: erysipelas, corns, lesions of scurvy. “For a felon (whitlow) cut off end of a lemon; insert finger and bind securely. In the morning remove exudation of matter.” (Chinese Barefoot doctor)

Preparations: Tincture Limonis P (1948) (dose, 2-4ml) is sometimes available but recorded successes have been chiefly due to use of the juice. Oil Lemon BP. Used also in Aromatherapy.

Note: When drinking lemon juice care should be taken to see juice does not come in direct contact with the teeth, the enamel of which it erodes. The juice may remove some calculi from the body, but after having cleared the bloodstream it leeches calcium from the teeth and bones. It is a known cause of arthritis, inducing dryness and subsequent erosion of cartilage of the joints. ... lemon