Erythr Health Dictionary

Erythr: From 1 Different Sources


Erythrasma

A super?cial mild infection of the skin caused by CORYNEBACTERIA. It produces pink or slightly brown ?aky areas of skin usually on the upper inner thighs or axillae. Toe clefts may be affected with thickened, white, macerated skin. The affected areas ?uoresce coral pink under ultraviolet light. CLOTRIMAZOLE or KETOCONAZOLE cream clears the rash rapidly. Very extensive erythrasma responds to oral ERYTHROMYCIN given for seven days.... erythrasma

Erythromycin

One of the MACROLIDES, it has an antibacterial spectrum similar, but not identical, to that of penicillin. The drug is a valuable alternative for patients who are allergic to penicillin. Erythromycin is used for respiratory infections, including spread within a family of WHOOPINGCOUGH, and also CHLAMYDIA, LEGIONNAIRE’S DISEASE, SYPHILIS and enteritis caused by CAMPYLOBACTER. It is also used with neomycin when preparing for bowel surgery. Though often active against penicillin-resistant staphylococci, these bacteria are now sometimes resistant to erythromycin. The drug may be given orally, intravenously or topically (for acne).... erythromycin

Erythroderma

A rare in?ammation of the skin which causes universal itching. The skin is red, thickened and scaly. It is also called generalised exfoliative dermatitis (see SKIN, DISEASES OF). It may complicate chronic eczema (see DERMATITIS) or PSORIASIS, particularly in men, in the second half of life. It may also result from HYPERSENSITIVITY to a drug, such as gold injections used in RHEUMATOID ARTHRITIS. Rarely, it may be a manifestation of T-cell LYMPHOMA.

Universal in?ammation of the skin may cause heart failure, particularly in elderly people with pre-existing heart disease. It may lead to HYPOTHERMIA due to excessive heat loss from the skin and protein de?ciency caused by the shedding of large quantities of skin scales containing keratin. Rarely, these complications can be fatal.

Treatment depends on the cause, but in eczematous erythroderma, oral CORTICOSTEROIDS (PREDNISOLONE) in full dosage may be needed.... erythroderma

Erythrocyte Sedimentation Rate

See ESR.... erythrocyte sedimentation rate

Erythropoietin

The protein, produced mainly in the kidney, that is the major stimulus for the production of ERYTHROCYTES, or red blood corpuscles. It is used when treating ANAEMIA dure to end-stage kidney failure and in premature newborns with anaemia. (See also BLOOD.)... erythropoietin

Erythrocyte

Another name for a red blood cell (see blood cells).... erythrocyte

Erythromelalgia

A condition in which the ?ngers or toes, or even larger portions of the limbs, become purple and bloated in appearance, and very painful. In people suffering from the condition – which is not a common one – the attacks come and go, being worse in summer (unlike chilblains), and worse on exertion or when the affected parts are warmed or allowed to hang down. The condition may appear without apparent cause, but is often associated with vascular diseases, such as HYPERTENSION and POLYCYTHAEMIA VERA. It aso occurs in association with certain diseases of the central nervous system, and in cases of metallic poisoning

(e.g. arsenic, mercury and thallium). Treatment is unsatisfactory but aspirin provides sympomatic relief.... erythromelalgia

Erythraea Roxburghii

G. Don.

Synonym: Centaurium roxburghii (G. Don) Druce.

Family: Gentianaceae.

Habitat: Sub-tropical and temperate regions.

Ayurvedic: Kiraat-tikta (related species), Yavatiktaa (related species) (A substitute for Swertia chirayita.)

Folk: Khet-chiraayataa.

Key application: Erythraea centaurium—in loss of appetite and peptic discomfort. (German Commission E.)... erythraea roxburghii

Erythrina Indica

Lam.

Synonym: E. variegata Linn. var. orientalis (Linn.) Merril.

Family: Papilionaceae; Fabaceae.

Habitat: Grown as an ornamental.

English: Indian Coral tree.

Ayurvedic: Paaribhadra, Paarib- hadraka, Paarijaataka, Mandaara, Dadap. Kantaki-palaasha, Kant- kimshuka, Raktapushpa; Nimba- taru. (Erythrina suberosa Roxb. is also equated with Paaribhadra.)

Siddha/Tamil: Kaliyanamurukkan.

Folk: Farhad.

Action: Leaf—cathartic, diuretic, antiseptic, anti-inflammatory. Applied externally for dispersing venereal buboes. Bark—antibilious, anthelmintic, febrifuge, astringent, expectorant. (E. variegata is an adulterant to the Ayurvedic drug Rohitaka.) Different parts of the plant are used as nervine sedative, antiepileptic, astringent, antiasthmatic and antiseptic. Bark is used in liver ailments, fever and rheumatism.

A number of tetracyclic alkaloids have been isolated from the plant.

The alkaloids showed a muscle relaxant activity and increased the sedative effects of hexabarbital. The alkaloids extracted from the leaves are reported to have anti-inflammatory activity. Bark alkaloids are neuromus- cular blocking, smooth muscle relaxant, CNS depressant, hydrocholeretic and anticonvulsant. The bark contains 0.05% alkaloids.

The root extracts exhibited antimicrobial activity in vitro against Staphy- lococcus aureus and Mycobacterium smegmatis.

The seeds of many of the species of Erythrina contain alkaloids with curare-like activity. Clinical trials on biologically standardized beta-ery- throidine hydrochloride and dihydro- beta-erythroidine hydrochloride have shown promising results in the treatment of conditions involving certain types of muscular rigidity.

Dosage: Stem bark—6-12 g powder; 12-24 g for decoction. (API Vol. II.)... erythrina indica

Erythrina Stricta

Roxb.

Family: Papilionaceae; Fabaceae.

Habitat: Assam, Manipur, West Bengal and South India.

Ayurvedic: Muraa (controversial).

Siddha/Tamil: Mullu-murukku.

Action: Bark—antibilious, an- tirheumatic, febrifuge, antiasth- matic, antiepileptic, antileprotic. Flowers—antidote to poison. In Assam, the juice of the root bark is given to children in threadworm infection.

The plant gave tetracyclic alkaloids— (+)-erythraline and (+)-erythrinine.... erythrina stricta

Erythroblastosis Fetalis

See HAEMOLYTIC DISEASE OF THE NEWBORN.... erythroblastosis fetalis

Erythroblasts

A series of nucleated cells in the bone marrow that go through various stages of development until they form ERYTHROCYTES. They may appear in the blood in certain diseases.... erythroblasts

Erythropoeisis

The process by which ERYTHROCYTES or red blood cells are produced. The initiating cell is the haemopoietic stem cell from which an identi?able proerythroblast develops. This goes through several stages as a normoblast before losing its nucleus to become an erythrocyte. This process takes place in the blood-forming bone-marrow tissue.... erythropoeisis

Erythraemia

See: POLYCYTHAEMIA VERA. ... erythraemia

Erythroblast

n. any of a series of nucleated cells (see normoblast; proerythroblast) that pass through a succession of stages of maturation to form red blood cells (*erythrocytes). Erythroblasts are normally present in the blood-forming tissue of the bone marrow, but they may appear in the circulation in a variety of diseases (see erythroblastosis). See also erythropoiesis.... erythroblast

Erythrocytes

The biconcave red blood cells that carry oxygen from the lungs to the tissues, and return carbon dioxide (see also RESPIRATION). They have an excess of membrane, some of which may be lost in various disorders, as a result of which they become progressively more spherical and rigid. Erythrocytes, which have no nuclei, are formed during ERYTHROPOEISIS from ERYTHROBLASTS in the BONE MARROW, and each mm3 of blood contains 5 million of them. They are by far the largest constituent among the blood cells and they contain large amounts of the oxygen-carrier HAEMOGLOBIN. They have a life of about 120 days after which they are absorbed by macrophages (see MACROPHAGE), the blood’s scavenging cells. Most components of the erythrocytes, including the red pigment haemoglobin, are re-used, though some of the pigment is broken down to the waste product BILIRUBIN.... erythrocytes

Erythroxylum Coca

Lam.

Family: Erythroxylaceae.

Habitat: Indigenus to Peru and Bolivia, introduced and experimentally cultivated in Assam, West Bengal, Bihar, Uttar Pradesh, Tamil Nadu and Kerala.

English: Coca, Cocaine Plant.

Siddha/Tamil: Sivadari.

Action: Mydriatic and toxic. (Coca leaf extract, after removing cocaine, is used as a flavouring agent for soft drinks. Maximum use level: 0.055%.) Coca leaves contain a large number of alkaloids including cocaine, tropa- cocaine, cinnamoylcocaine, truxillines and benzoylecgonine. (alkaloid content varies from 0.5 to 1.5%). The bark and seeds also contain cocaine.

Coca is subject to restrictions in most countries.

Not to be confused with Cocoa seed (Theobroma cacao.)... erythroxylum coca

Erythroxylum Monogynum

Roxb.

Synonym: E. indicum (DC.) Bedd.

Family: Erythroxylaceae.

Habitat: South India, up to 1,000 m.

English: Bastard Sandal, Red Cedar.

Ayurvedic: Kattuchandanam (Kerala).

Siddha/Tamil: Devadaram.

Folk: Gandh-giri (Maharashtra).

Action: Leaf—diaphoretic, stimulant, diuretic, stomachic. A decoction is used for malarial fever. Bark and wood—febrifuge.

The wood yields diterpenes, including monogynol, OH-ogynol, devada- rool; d-hibaene, its epoxide and an olefinic hydrocarbon.

Biological activity of the plant is hypothermic and CNS active.... erythroxylum monogynum

Erythroblastosis

n. the presence in the blood of the nucleated precursors of the red blood cells (*erythroblasts). This may occur when there is an increase in the rate of red cell production, as in haemorrhagic or haemolytic *anaemia, or in infiltrations of the bone marrow by tumours, etc.... erythroblastosis

Erythroblastosis Foetalis

a severe but rare haemolytic *anaemia affecting newborn infants due to destruction of the infant’s red blood cells by factors present in the mother’s serum. It is usually caused by incompatibility of the rhesus blood groups between mother and infant (see rhesus factor).... erythroblastosis foetalis

Erythrocyanosis

n. mottled purplish discoloration on the legs and thighs, usually of adolescent girls or obese boys before puberty. The disorder sometimes occurs in older women and is worse in cold weather. Weight loss is the best treatment because it reduces the insulating effect of a thick layer of fat.... erythrocyanosis

Erythrocytic

adj. describing those stages in the life cycle of the malarial parasite (see Plasmodium) that develop inside the red blood cells (see trophozoite). Compare exoerythrocytic.... erythrocytic

Erythroedema

n. see pink disease.... erythroedema

Erythrogenesis

n. a former name for *erythropoiesis.... erythrogenesis

Erythron

n. circulating mature red blood cells and that part of the blood-forming system of the body that is directed towards the production of red blood cells. The erythron is not a single organ but is dispersed throughout the blood-forming tissue of the *bone marrow. See also erythropoiesis.... erythron

Erythropenia

n. a reduction in the number of red blood cells (*erythrocytes) in the blood. This usually, but not invariably, occurs in *anaemia.... erythropenia

Erythroplasia

n. an abnormal red patch of skin that occurs particularly in the mouth or on the genitalia and is precancerous. Erythroplasia of Queyrat is a nonkeratinizing *carcinoma in situ affecting the glans of the penis or the inner surface of the prepuce. It is ten times more likely to progress to invasive squamous cell carcinoma than is *Bowen’s disease of the penis. Compare leukoplakia.... erythroplasia

Erythropoiesis

n. the process of red blood cell (*erythrocyte) production, which normally occurs in the blood-forming tissue of the *bone marrow. The ultimate precursor of the red cell is the *haemopoietic stem cell, but the earliest precursor that can be identified microscopically is the *proerythroblast. This divides and passes through a series of stages of maturation termed respectively early, intermediate, and late *normoblasts, the latter finally losing its nucleus to become a mature red cell. See also haemopoiesis.... erythropoiesis

Erythropsia

n. red vision: a symptom sometimes experienced after removal of a cataract and also in snow blindness.... erythropsia

Erythrovirus

n. see parvovirus.... erythrovirus

Palmoplantar Erythrodysaesthesia

(hand–foot syndrome) a skin reaction marked by redness, numbness, and desquamation of the palms of the hands and soles of the feet. It can be caused by many chemotherapy drugs, particularly fluorouracil and capecitabine, and tyrosine kinase inhibitors. Treatment requires cessation of the drug.... palmoplantar erythrodysaesthesia



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