Febrifuge Health Dictionary

Ficus spp.

Moraceae

The genus Ficus constitutes an important group of trees with immense medicinal value. It is a sacred tree of Hindus and Buddhists. Among the varied number of species, the most important ones are the four trees that constitute the group “Nalpamaram”, namely, F. racemosa, F. microcarpa, F. benghalensis and F. religiosa (Athi, Ithi, Peral and Arayal respectively).

1. Ficus racemosa Linn. syn. F. glomerata Roxb.

Eng: Cluster fig, Country fig

San: Udumbarah, Sadaphalah

Hin: Gular, Umar

Ben: Jagya dumur

Mal, Tam,

Kan: Athi

Tel: Udambaramu, Paidi

Gular fig, Cluster fig or Country fig, which is considered sacred, has golden coloured exudate and black bark. It is distributed all over India. Its roots are useful in treating dysentery. The bark is useful as a wash for wounds, highly efficacious in threatened abortions and recommended in uropathy. Powdered leaves mixed with honey are given in vitiated condition of pitta. A decoction of the leaves is a good wash for wounds and ulcers. Tender fruits (figs) are used in vitiated conditions of pitta, diarrhoea, dyspepsia and haemorrhages. The latex is administered in haemorrhoids and diarrhoea (Warrier et al, 1995). The ripe fruits are sweet, cooling and are used in haemoptysis, thirst and vomiting (Nadkarni, 1954; Aiyer et al, 1957; Moos, 1976). Nalpamaradi coconut oil, Candanasava, Valiya Arimedastaila, Dinesavalyadi Kuzhambu, Abhrabhasma, Valiya candanaditaila, etc. are some important preparations using the drug (Sivarajan et al, 1994).

It is a moderate to large-sized spreading laticiferous, deciduous tree without many prominent aerial roots. Leaves are dark green and ovate or elliptic. Fruit receptacles are 2-5cm in diameter, sub- globose or pyriform arranged in large clusters on short leafless branches arising from main trunk or large branches. Figs are smooth or rarely covered with minute soft hairs. When ripe, they are orange, dull reddish or dark crimson. They have a pleasant smell resembling that of cedar apples. The bark is rusty brown with a fairly smooth and soft surface, the thickness varying from 0.5-2cm according to the age of the trunk or bark. Surface is with minute separating flakes of white tissue. Texture is homogeneously leathery (Warrier et al, 1995).

Stem-bark gives gluanol acetate, -sitosterol, leucocyanidin-3-O- -D-glucopyrancoside, leucopelargonidin-3-O- -D-glucopyranoside, leucopelargonidin -3-O- -L-rhamnopyranoside, lupeol, ceryl behenate, lupeol acetate and -amyrin acetate. Stem- bark is hypoglycaemic and anti-protozoal. Gall is CVS active. Bark is tonic and used in rinder pest diseases of cattle. Root is antidysenteric and antidiabetic. Leaf is antibilious. Latex is antidiarrhoeal and used in piles. Bark and syconium is astringent and used in menorrhagia (Husain et al, 1992).

2. Ficus microcarpa Linn. f. syn. F. retusa auct. Non. Linn.

San: Plaksah; Hin,

Ben: Kamarup;

Mal: Ithi, Ithiyal;

Tam: Kallicci, Icci;

Kan: Itti;

Tel: Plaksa

Plaksah is the Ficus species with few branches and many adventitious roots growing downward. It is widely distributed throughout India and in Sri Lanka, S. China, Ryuku Isles and Britain. Plakasah is one of the five ingredients of the group panchvalkala i.e, five barks, the decoction of which is extensively used to clear ulcers and a douche in leucorrhoea in children. This decoction is administered externally and internally with satisfactory results. Plaksah is acclaimed as cooling, astringent, and curative of raktapitta doshas, ulcers, skin diseases, burning sensation, inflammation and oedema. It is found to have good healing property and is used in preparation of oils and ointments for external application in the treatment of ulcers (Aiyer and Kolammal, 1957). The stem-bark is used to prepare Usirasava, Gandhataila, Nalpamaradi taila, Valiya marmagulika, etc. (Sivarajan et al, 1994). The bark and leaves are used in wounds, ulcers, bruises, flatulent colic, hepatopathy, diarrhoea, dysentery, diabetes, hyperdipsia, burning sensation, haemaorrhages, erysipelas, dropsy, ulcerative stomatitis, haemoptysis, psychopathy, leucorrhoea and coporrhagia (Warrier et al,1995) F. microcarpa is a large glabrous evergreen tree with few aerial roots. Leaves are short- petioled, 5-10cm long, 2-6cm wide and apex shortly and bluntly apiculate or slightly emarginate. Main lateral nerves are not very prominent and stipules are lanceolate. Fruit receptacles are sessile and globose occurring in axillary pairs. It is yellowish when ripe without any characteristic smell. Bark is dark grey or brown with a smooth surface except for the lenticels. Outer bark is corky and crustaceous thin and firmly adherent to inner tissue. Inner bark is light and flesh coloured with firbrous texture (Warrier et al, 1995). It is also equated with many other species of the genus. viz. F. Singh and Chunekar, 1972; Kapoor and Mitra, 1979; Sharma, 1983).

The bark contains tannin, wax and saponin. Bark is antibilious. Powdered leaves and bark is found very good in rheumatic headache. The bark and leaves are astringent, refrigerant, acrid and stomachic.

3. Ficus benghalensis Linn.

Eng: Banyan tree; San: Nyagrodhah, Vatah;

Hin: Bat, Bargad;

Ben: Bar, Bot; Mar: Vada; Mal: Peral, Vatavriksham;

Tam: Alamaram, Peral;

Kan: Ala;

Tel: Peddamarri;

Guj: Vad

Banyan tree is a laticiferous tree with reddish fruits, which is wound round by aerial adventitious roots that look like many legs. It is found in the Sub-Himalayan tract and Peninsular India. It is also grawn throughout India. It is widely used in treatment of skin diseases with pitta and rakta predominance. Stem-bark, root -bark, aerial roots, leaves, vegetative buds and milky exudate are used in medicine. It improves complexion, cures erysepelas, burning sensation and vaginal disorders, while an infusion of the bark cures dysentery, diarrhoea, leucorrhoea, menorrhagia, nervous disorders and reduces blood sugar in diabetes. A decoction of the vegetative buds in milk is beneficial in haemorrhages. A paste of the leaves is applied externally to abcesses and wounds to promote suppuration, while that of young aerial roots cure pimples. Young twigs when used as a tooth brush strengthen gum and teeth (Nadkarni, 1954; Aiyer and Kolammal, 1957; Mooss,1976). The drug forms an important constituent of formulations like Nalpamaradi Coconut oil, Saribadyasava, Kumkumadi taila, Khadi ra gulika, Valiyacandanadi taila, Candanasava, etc. (Sivarajan et al, 1994). The aerial roots are useful in obstinate vomiting and leucorrhoea and are used in osteomalacia of the limbs. The buds are useful in diarrhoea and dysentery. The latex is useful in neuralgia, rheumatism, lumbago, bruises, nasitis, ulorrhagia, ulitis, odontopathy, haemorrhoids, gonorrhoea, inflammations, cracks of the sole and skin diseases (Warrier et al, 1995).

It is a very large tree up to 30m in height with widely spreading branches bearing many aerial roots functioning as prop roots. Bark is greenish white. Leaves are simple, alternate, arranged often in clusters at the ends of branches. They are stipulate, 10-20cm long and 5-12.5cm broad, broadly elliptic to ovate, entire, coriaceous, strongly 3-7 ribbed from the base. The fruit receptacles are axillary, sessile, seen in pairs globose, brick red when ripe and enclosing male, female and gall flowers. Fruits are small, crustaceous, achenes, enclosed in the common fleshy receptacles. The young bark is somewhat smooth with longitudinal and transverse row of lenticels. In older bark, the lenticels are numerous and closely spaced; outer bark easily flakes off. The fresh cut surface is pink or flesh coloured and exudes plenty of latex. The inner most part of the bark adjoining the wood is nearly white and fibrous (Warrier et al, 1995).

The bark yields flavanoid compounds A, B and C; A and C are identified as different forms of a leucoanthocyanidin and compound B a leucoanthocyanin. All the 3 were effective as hypoglycaemic agents. Leaves give friedelin, -sitosterol, flavonoids- quercetin-3-galactoside and rutin. Heart wood give tiglic acid ester of taraxasterol. Bark is hypoglycemic, tonic, astringent, antidiarrhoeal and antidiabetic. Latex is antirheumatic. Seed is tonic. Leaf is diaphoretic. Root fibre is antigonorrhoeic. Aerial root is used in debility and anaemic dysentery (Husain et al, 1992).

.4. Ficus religiosa Linn.

Eng:Peepal tree, Sacred fig; San:Pippalah, Asvatthah; Hin:Pippal, Pipli, Pipar; Mal:Arayal

Ben: Asvatha;

Tam: Arasu, Asvattam;

Kan: Aswatha;

Tel: Ravi; Mar: Ashvata, Pimpala

Peepal tree or Sacred fig is a large deciduous tree with few or no aerial roots. It is common throughout India, often planted in the vicinity of the temples. An aqueous extract of the bark has an antibacterial activity against Staphylococcus aureus and Escherichia coli. It is used in the treatment of gonorrhoea, diarrhoea, dysentery, haemorrhoids and gastrohelcosis. A paste of the powdered bark is a good absorbent for inflammatory swellings. It is also good for burns. Leaves and tender shoots have purgative properties and are also recommended for wounds and skin diseases. Fruits are laxative and digestive. The dried fruit pulverized and taken in water cures asthma. Seeds are refrigerant and laxative. The latex is good for neuralgia, inflammations and haemorrhages (Warrier et al, 1995). Decoction of the bark if taken in honey subdues vatarakta (Nadkarni, 1954; Aiyer and Kolammal, 1957; Mooss, 1976; Kurup et al, 1979). The important preparations using the drug are Nalpamaradi taila, Saribadyasava, Candanasava, Karnasulantaka, Valiyamarma gulika etc (Sivarajan et al, 1994). branches bearing long petioled, ovate, cordate shiny leaves. Leaves are bright green, the apex produced into a linear-lanceolate tail about half as long as the main portion of the blade. The receptacles occurring in pairs and are axillary, depressed globose, smooth and purplish when ripe. The bark is grey or ash coloured with thin or membranous flakes and is often covered with crustose lichen patches. The outer bark is not of uniform thickness, the middle bark in sections appear as brownish or light reddish brown. The inner part consists of layers of light yellowish or orange brown granular tissue (Warrier et al, 1995).

Bark gives -sitosterol and its glucoside. Bark is hypoglycaemic. Stem bark is antiprotozoal, anthelmintic and antiviral. Bark is astringent, antigonorrheic, febrifuge, aphrodisiac and antidysenteric. Syconium, leaf and young shoot is purgative (Husain et al, 1992).

Agrotechnology: Ficus species can be cultivated in rocky areas, unused lands, or other wastelands of the farmyard. The plant is vegetatively propagated by stem cuttings. A few species are also seed propagated. Stem cuttings of pencil thickness taken from the branches are to be kept for rooting. Rooted cuttings are to be transplanted to prepared pits. No regular manuring is required. Irrigation is not a must as a plant is hardy. The plant is not attacked by any serious pests or diseases. Bark can be collected after 15 years. Ficus species generally has an economic life span of more than hundred years. Hence bark can be regularly collected from the tree. Root, bark, leaves, fruits and latex form the economic parts (Prasad et al,1995).... ficus

Alstonia venenata

Apocynaceae

San: Visaghni, Anadana;

Mal: Analivegam;

Tam: Sinnappalai;

Kan: Addasarpa

Importance: Alstonia is a large shrub with straight bole and growing upto about 6m height. The roots are useful in skin diseases, erysipelas, leprosy, cobra bite and other venomous bites, epilepsy, fatigue, fever and otalgia. The fruits are useful in syphilis, insanity and epilepsy. The plant is believed to repel snakes.

Distribution: The plant is distributed throughout India in deciduous forests in areas up to 1800m elevation.

Botany: Alstonia venenata R.Br., belonging to the family Apocynaceae, is a large shrub to small tree up to 6m in height with greyish brown bark and bright yellow hard and woody root. Leaves are simple, arranged in whorls of 3-6, membranous, lanceolate, margins wavy, finely acuminate, main nerves numerous, close, parallel and united by inter marginal nerve. Flowers are white, arranged in terminal sub umbellate cymes or in racemes. Fruits are fusiform with stalked and beaked follicles, tapering at both ends. Seeds are many flattened with a tuft of hair at each end (Warrier et al, 1993). Other important species belonging to the genus Alstonia are the following.

1. A. scholaris R. Br.

This tree is common throughout India. The bark is valuable in debility and after effects of fever, chronic diarrhoea, dysentery and catarrhal fever. The milky juice is applied to ulcers and rheumatic pains, mixed with oil and dropped into ear to relieve earache. Ditanin is the active principle of the bark, possessing powerful febrifuge properties. The bark is astringent, tonic and febrifuge (Nadkarni, 1998).

2. A. spectabilis R. Br.

It is a large evergreen tree seen in tropical forests of Andamans. The bark contains alkaloids such as alstonamine, ditamine, echitamine and echitenine (Chopra et al,1980)

Agrotechnology: The plant is propagated mainly by seeds. Seeds are to be sown on seedbeds and germinated ones are to be transferred to polybags. About three months old seedlings are used for transplanting. If seeds are not available, thin stem cuttings can be planted in polybags and rooted cuttings used. Pits of size 60cm cube are to be taken at 3m spacing, filled with dried cowdung, sand and topsoil and made into a mound. To this mounds seedlings from polybags are to be transplanted. Irrigation is essential during early stages of growth. Application of organic manure every year is beneficial. Regular weeding is to be done. The plant is not attacked by any serious pests or diseases. Flowers are formed in the first year itself. It can be used for medicinal purposes after seven years of growth. Fruits and roots are the economical parts (Prasad et al,1997).

Properties and activity: The plant is a rich source of indole alkaloids. Alkaloids are present in various parts. Stem bark and root contain venenatine, alstovenine, 3-dehydroalstovenine and reserpine. Stem bark contains venoxidine (venenatine Nb -oxide), anhydroalstonatine, kopsinine, venalstonine, venalstonidine(venalstonine-6,7-epoxide), echitovenine and veneserpine. Fruits contain echitovenidine, (+)minovincinine, echitoserpidine, echitoserpine, echitoveniline, 11-methoxy echitovonidine, 11-methoxy (-) minovinicinine, echitoserpiline, (-)vincadifformine, 11-methoxy(-)vincadifformine and venoterpine. Leaves contain echitovenaldine, echitoveniline, alstolenine, deacetylakuammiline, polynuridine, dihydropolynuridine and raucaffrininoline. The yellow tint in bark is because of the presence of 3-alstovenine. A number of indole alkaloids have been further isolated from the plant. In addition to alkaloids fruits contain -amyrin acetate and lupeol ester of -hydroxy acid (Husain et al,1992).

The root is bitter, astringent, thermogenic, depurative, antitoxic, febrifuge and anodyne. The alkaloid alstovenine in lower doses exhibited monoamine oxidase inhibitor activity, while in higher doses it showed marked central stimulant effect. Veninatine exhibited reserpine like activity. Alcoholic extract of the fruits showed initial activation effect on acetylcholine esterase, followed alternately by inhibition and activation of the enzyme.... alstonia

Hyssopus officinalis. N.O. Labiateae,

Habitat: Cultivated in gardens.

Features ? Stem woody, to a height of about two feet. Leaves opposite, small, nearly sessile, lanceolate, hairy at margins. Flowers bluish-purple, in small axillary clusters on one side. Camphor-like odour.

Part used ? Herb.

Action: Stimulant, pectoral, carminative, diaphoretic, febrifuge.

In cough and cold prescriptions, particularly for whooping cough, and in other troubles of infancy. The 1 ounce to 1 pint infusion is given in wineglass doses, or according to age.... hyssop

Eupatorium perfoliatum. N.O. Compositae.

Synonym: Indian Sage, Thoroughwort.

Habitat: Damp places.

Features ? One or more erect stems, branched at top. Leaves opposite, lanceolate, four to six inches long, united at base, crenate edges, tiny, yellow resin dots beneath. Flowers August to October. Persistently bitter taste.

Part used ? Herb.

Action: Diaphoretic, febrifuge, tonic, laxative, expectorant.

Influenza and feverish conditions generally, for which purpose it is very successfully used by the American negroes. Also used in catarrhs. The infusion of 1 ounce to 1 pint boiling water may be given in wineglassful doses frequently, hot as a diaphoretic and febrifuge, cold as a tonic.

F. H. England, of the College of Medicine and Surgery, Chicago (Physio- Medical) says ? "It is a pure relaxant to the liver. It acts slowly and persistently. Its greatest power is manifested upon the stomach, liver, bowels and uterus."... boneset

Cymbopogon winterianus, Jowitt. Leaves.

Fragrant oil extracted from an Asian perennial grass. Rarely used internally.

Action: antirheumatic, strong insect repellent, febrifuge, diaphoretic, antispasmodic. Uses: Muscular rheumatism.

External: Locally to repel insects and vermin. ... citronella

Eclipta prostrata

Asteraceae

San: Bhrngarajah, Tekarajah;

Hin: Bhamgra, Mocakand, Babri;

Ben: Kesutthe, Kesraj;

Mal: Kannunni, Kayyonni, Kayyunnni;

Tam: Kayyantakara, Kaikeri;

Kan: Kadiggagaraga;

Tel: Guntagalijeran; Arab: Kadim-el-bint

Importance: Eclipta is one of the ten auspicious herbs that constitute the group dasapuspam which is considered to destroy the causative factors of all unhealthy and unpleasant features and bestow good health and prosperity. The members of this group cure wounds and ulcers as well as fever caused by the derangement of the tridosas - vata, pitta and kapha. It is used in hepatitis, spleen enlargements, chronic skin diseases, tetanus and elephantiasis. The leaf promotes hair growth and use as an antidote in scorpion sting. The root is used as an emetic, in scalding of urine, conjuctivitis and as an antiseptic to ulcers and wound in cattle. It is used to prevent abortion and miscarriage and also in cases of uterine pains after the delivery. The juice of the plant with honey is given to infants for expulsion of worms. For the relief in piles, fumigation with Eclipta is considered beneficial. A decoction of the leaves is used in uterine haemorrhage. The paste prepared by mincing fresh plants has got an antiinflammatory effect and may be applied on insect bites, stings, swellings and other skin diseases. In Ayurveda, it is mainly used in hair oil, while in Unani system, the juice is used in “Hab Miskeen Nawaz” along with aconite, triphala, Croton tiglium, Piper nigium, Piper longum, Zingiber officinale and minerals like mercury, sulphur, arsenic, borax, etc. for various types of pains in the body. It is also a constituent of “Roghan Amla Khas” for applying on the hair and of “Majun Murrawah-ul-arwah”.

Distribution: This plant is widely distributed in the warm humid tropics with plenty of rainfall. It grows commonly in moist places as a weed all over plains of India.

Botany: Eclipta prostrata (Linn) Linn. syn. E. alba Hassk. is an annual, erect or postrate herb, often rooting at nodes. Leaves are sessile, 2.5-7.5cm long with white appressed hairs. Floral heads are 6-8 mm in diameter, solitary and white. Fruit is an achene, compressed and narrowly winged. Sometimes, Wedelia calendulacea, which resembles Eclipta prostrata is used for the same purpose.

Properties and activity: The leaves contain stigmasterol, -terthienylmethanol, wedelolactone, dismethylwedelolactone and dismethylwedelolactone-7-glucoside. The roots give hentriacontanol and heptacosanol. The roots contain polyacetylene substituted thiophenes. The aerial part is reported to contain a phytosterol, -amyrin in the n-hexane extract and luteolin-7-glucoside, -glucoside of phytosterol, a glucoside of a triterpenic acid and wedelolactone in polar solvent extract. The polypeptides isolated from the plant yield cystine, glutamic acid, phenyl alanine, tyrosine and methionine on hydrolysis. Nicotine and nicotinic acid are reported to occur in this plant.

The plant is anticatarrhal, febrifuge, antidontalgic, absorbent, antihepatic, CVS active, nematicidal, ovicidal and spasmolytic in activity. The alcoholic extract of entire plant has been reported to have antiviral activity against Ranikhet disease virus. Aqueous extract of the plant showed subjective improvement of vision in the case of refractive errors. The herbal drug Trefoli, containing extracts of the plant in combination with others, when administered to the patients of viral hepatitis, produced excellent results.... eclipta

Allium sativum

Liliaceae

San: Lasunah, Rasonah;

Hin:Lasun, Lahasun;

Ben: Lashan;

Mal: Vellulli;

Kan: Belluli;

Tam: Vellaipuntu; Mar: Lasunas; Ass: Naharu; Tel:Vellulli, Tella-gadda;

Guj: Lasan

Importance: Garlic is one of the important bulb crops used as a spice or condiment with medicinal value throughout the world. It possesses high nutritive value. Its preparations are useful in vitiated conditions of kapha and vata, cough, whooping cough, bronchitis, asthma, fever, facial paralysis, flatulence, colic, constipation, atonic dyspepsia, helminthiasis, duodenal ulcers, pulmonary and laryngeal tuberculosis, opthalmopathy, cardiopathy, fatigue, leucoderma, leprosy, hysteria, haemorrhoids, sciatica, otalgia, lumbago, swellings, splenopathy, hepatopathy, pneumonopathy, anthralgia, sore eyes, ear ache and dental caries (Kumar et al, 1997).

Distribution: Garlic is a native of Southern Europe and it is cultivated all over the world.. It is grown throughout India; Gujarat and Orissa being the leading states.

Botany: The genus Allium of Liliaceae family comprises a number of species. The important ones are the following:

A. sativum Linn. syn. A. porrum Linn.

A. cepa Linn.

A. ampeloprasum Linn.

A. ascalonicum Linn. A. leptophyllum Wall. A. macleanii Baker.

A. schoenoprasum Linn.

A. tuberosum Roxb.

Allium sativum is a scapigerous foetid perennial medicinal herb with underground compound bulbs covered over by outer white thin scales and with simple smooth, round stem, surrounded at the bottom by tubular leaf sheath. The leaves are simple, long, flat and linear. The flowers are small and white arranged in rounded umbels mixed with small bulbils. The entire umbel is enclosed in a tear-drop-shaped membranous spathe. Flowers are usually sterile (Warrier et al, 1993).

Agrotechnology: Garlic can be grown under a wide range of climatic conditions. It prefers moderate temperature in summer as well as in winter. Short days are very favourable for the formation of bulbs. Garlic requires well drained loamy soils rich in humus, with fairly good content of potash. Garlic is propagated by cloves or bulblets. In the hills, sowing is done in April and May. Types with bold and compact cloves and thick white covering sheath are preferred for planting. Ootty-1 garlic is an improved variety by clonal selection released from TNAU, Coimbatore. Garlic may be broadcast, planted in furrows or dibbled at the rate of 150-200kg cloves/ha. In furrow planting, cloves are dropped 7.5-10cm apart in furrows 15cm deep and covered lightly with loose soil. Cloves may be dibbled 5 to 7.5cm deep and 7.5cm apart in rows which are 15cm apart with their growing end upwards and then covered with loose soil. A basal dose of 60kg N and 50kg each of P2O5 and K2O are applied along with 25t/ha of FYM. 60kg N is given as topdressing 45 days after planting. First irrigation is given immediately after sowing and subsequent irrigations are given at 10-15 days interval depending upon the soil moisture availability. The last irrigation should be given 2-3 days before harvesting to facilitate easy harvest and minimum damage to bulbs. First weeding and hoeing is to be done at one mo nth after sowing followed by a second weeding one month after first interculture. Hoeing at about two and a half months from sowing loosens the soil and helps in setting of bigger and well-filled bulbs. Garlic is attacked by Thrips tabacii which causes withering of leaves. Application of methyl demeton 25EC or dimethoate 30EC at 1ml/l will check the pest incidence. Leaf spot caused by Alternaria solanii can be controlled by spraying Dithane M.45 at fortnightly intervals at 2.5g/l of water. Garlic is harvested when the tops turn yellowish or brownish and show signs of drying up. The plants are uprooted, tied into small bundles and kept in shade for 2-3 days for curing. Average yield of garlic is 6-8t/ha. (Kumar et al, 1997.)

Properties and activity: Garlic bulb is reported to contain volatile oil, alliin (S-allyl-L-cysteine sulfoxide), S-methyl-L-cysteine sulfoxide and allinase. It is rich in vitamins like thiamine, riboflavine and niacin. Volatile oil contains allicin (diallyl thiosulphinate), an active odour principle of garlic. Other major compounds present are diallyl disulphide, diallyl trisulphide, allyl methyl trisulphide and allyl methyl disulphide (Husain et al., 1992).

Garlic bulb is antirheumatic, stimulant, diaphoretic, expectorant, diuretic, antispasmodic, astringent, antiparalytic, antileprotic, aperient, febrifuge, carminative, stomachic, alterative and emmenagogue. The essential oil is hypocholestrolemic, hypotensive, antitumour and antidiabetic. Diallyl disulphide and diallyl trisulphide from essential oil have larvicidal action. Bulbs also have anti-bacterial, and anti-fungal activity.... garlic

Andrographis paniculata

Acanthaceae

San: Bhunimbah, Kiratatiktah

Hin: Kakamegh, Kalpanath

Ben: Kalmegh

Mal: Nilaveppu, Kiriyattu Tam: Nilavempu Kan: Kreata

Importance: Kalmegh, the Great or Green Chiretta is a branched annual herb. It is useful in hyperdipsia, burning sensation, wounds, ulcers, chronic fever, malarial and intermittent fevers, inflammations, cough, bronchitis, skin diseases, leprosy, pruritis, intestinal worms, dyspepsia, flatulence, colic, diarrhoea, dysentery, haemorrhoids and vitiated conditions of pitta (Warrier et al, 1993). It is used to overcome sannipata type of fever, difficulty in breathing, hemopathy due to the morbidity of kapha and pitta, burning sensation, cough, oedema, thirst, skin diseases, fever, ulcer and worms. It is also useful in acidity and liver complaints (Aiyer and Kolammal, 1962). The important preparations using the drug are Tiktakagheta, Gorocandi gulika, Candanasava, Panchatiktam kasaya, etc. (Sivarajan et al, 1994). A preparation called “Alui” is prepared by mixing powdered cumin (Cuminium cyminum) and large cardamom (Amomum subulatum) in the juice of this plant and administered for the treatment of malaria (Thakur et al, 1989). It is also a rich source of minerals.

Distribution: The plant is distributed throughout the tropics. It is found in the plains of India from U.P to Assam, M.P., A.P, Tamil Nadu and Kerala, also cultivated in gardens.

Botany: Andrographis paniculata (Burm.f.) Wall ex.

Nees belongs to the family Acanthaceae. It is an erect branched annual herb, 0.3-0.9m in height with quadrangular branches. Leaves are simple, lanceolate, acute at both ends, glabrous, with 4-6 pairs of main nerves. Flowers are small, pale but blotched and spotted with brown and purple distant in lax spreading axillary and terminal racemes or panicles. Calyx-lobes are glandular pubescent with anthers bearded at the base. Fruits are linear capsules and acute at both ends. Seeds are numerous, yellowish brown and sub-quadrate (Warrier et al,1993).

Another species of Andrographis is A. echioides (Linn.) Nees. It is found in the warmer parts of India. The plant is a febrifuge and diuretic. It contains flavone-echiodinin and its glucoside-echioidin (Husain et al, 1992).

Agrotechnology: The best season of planting Andrographis is May-June. The field is to be ploughed well, mixed with compost or dried cowdung and seedbeds of length 3m, breadth 1/2m and 15cm height are to be taken at a distance of 3m. The plant is seed propagated. Seeds are to be soaked in water for 6 hours before sowing. Sowing is to be done at a spacing of 20cm. Seeds may germinate within 15-20 days. Two weedings, first at one month after planting and the second at 2 month after planting are to be carried out. Irrigation during summer months is beneficial. The plant is not attacked by any serious pests or diseases. Flowering commences from third month onwards. At this stage, plant are to be collected, tied into small bundles and sun-dried for 4-5 days. Whole plant is the economic part and the yield is about 1.25t dried plants/ha (Prasad et al, 1997).

Properties and activity: Leaves contain two bitter substances lactone “andrographolid” and “kalmeghin”. The ash contains sodium chloride and potassium salts. Plant is very rich in chlorophyte. Kalmeghin is the active principle that contains 0.6% alkaloid of the crude plant. The plant contains diterpenoids, andrographolide, 14-deoxy-11-oxo-andrographolide, 14-deoxy-11,12-dihydroandrographolide, 14-deoxy andrographolide and neoandrographolide (Allison et al, 1968). The roots give flavones-apigenin-7,4-dio-O-methyl ether, 5-hydroxy-7,8,2’,3’- tetramethoxyflavone, andrographin and panicolin and -sitosterol (Ali et al, 1972; Govindachari et al, 1969). Leaves contain homoandrographolide, andrographosterol and andrographone.

The plant is vulnerary, antipyretic, antiperiodic, anti-inflammatory, expectorant, depurative, sudorific, anthelmintic, digestive, stomachic, tonic, febrifuge and cholagogue. The plant is antifungal, antityphoid, hepatoprotective, antidiabetic and cholinergic. Shoot is antibacterial and leaf is hypotensive(Garcia et al, 1980). This is used for the inflammation of the respiratory tract. In China, researchers have isolated the andrographolide from which soluble derivative such as 14-deoxy-11, 12-dehydro-andrographolide which forms the subject of current pharmacological and clinical studies. Apigenin 7,4’-O-dimethyl ether isolated from A. paniculata exhibits dose dependent, antiulcer activity in shay rat, histamine induced ulcer in guinea pigs and aspirin induced ulcers in rats. A crude substance isolated from methanolic extract of leaves has shown hypotensive activity. Pre-treatment of rats with leaf (500mg/kg) or andrographolide (5mg/kg) orally prevented the carbon tetrachloride induced increase of blood serum levels of glutamate-oxaloacetate transaminase in liver and prevented hepatocellular membrane.... green chiretta

Cassia senna

Caesalpiniaceae

San: Svarnapatri;

Hin: Sanay, Sana Ka Patt;

Ben: Sonamukhi;

Mal: Sunnamukki, Chonnamukki, Nilavaka;

Tam: Nilavirai, Nilavakai;

Tel: Netatangedu

Importance: Indian Senna or Tinnevelly senna is a shrub very highly esteemed in India for its medicinal value. The leaves are useful in constipation, abdominal disorders, leprosy, skin diseases, leucoderma, splenomegaly, hepatopathy, jaundice, helminthiasis, dyspepsia, cough, bronchitis, typhoid fever, anaemia, tumours and vitiated conditions of pitta and vata (Warrier et al,1994). It is used in Ayurvedic preparations; “Pancha Sakara Churna”, “Shat Sakara Churna” and “Madhu Yastyadi Churna” used for constipation. Its use is widespread in Unani system and some of the important products of this system containing senna are “Itrifal Mulayyin”, “Jawarish Ood Mulayyin”, “Hab Shabyar”, “Sufuf Mulliyin”, “Sharbat Ahmad Shahi”, etc. used as a mild laxative (Thakur et al, 1989).

Distribution: The plant is of Mediterranean origin. It is found in Somalia, Saudi Arabia, parts of Pakistan and Kutch area of Gujarat. It is largely cultivated in Tirunelveli, Ramanathapuram, Madurai and Salem districts of Tamil Nadu.

Botany: The genus Cassia, belonging to the family Caesalpiniaceae, comprises of a number of species, namely,

C. senna Linn. syn. C. angustifolia Vahl.

C. absus Linn.

C. alata Linn.

C. auriculata Linn.

C. burmanni Wight. syn. C. obovata (Linn.) Collad.

C. glauca Lam.

C. javanica Linn.

C. mimosoides Linn.

C. obtusifolia Linn. syn. C. tora Linn.

C. occidentalis Linn.

C. pumila Lam.

C. slamea Lam.

C. acutifolia Delile.

C. sophera Linn.

C. senna is a shrub or undershrub, 60-75cm in height with pale subterete or obtusely angled erect or spreading branches. Leaves are paripinnate. Leaflets are 5-8 in number, ovate-lanceolate and glabrous. Flowers are yellowish, many and arranged in axillary racemes. Fruits are flat legumes, greenish brown to dark brown and nearly smooth (Chopra et al,1980, Warrier et al,1994).

In commerce, the leaves and pods obtained from C. senna are known as “ Tinnevelly Senna” and those from C. acutifolia Delile. as “Alexandrian Senna”. The leaves of C. acutifolia are narrower than C. senna, otherwise both resemble to a large extent (Thakur et al, 1989). All the true Sennas have the portions of their leaves unequally divided. In some kinds the lower part of one side is reduced to little more than a line in breadth, while the other is from a quarter to half an inch in breadth. The drug known under the name of East Indian Senna is nearly free from adulteration; and as its properties appear identical with those of the Alexandrian and the price being less, it probably will supersede it in general practice. Its size and shape readily identify it (Graves, 1996).

Agrotechnology: The plant requires a mild subtropical climate with warm winters which are free from frost for its growth. Semiarid areas with adequate irrigation facilities are ideal for cultivation. Areas having high rainfall, humidity and poor drainage are not suitable. Light or medium loamy soils with adequate drainage and pH varying from 7.0-8.2 are preferable. In South India both summer and winter crops are possible. The plant is propagated by seeds. The seed rate required is 15-20kg/ha. Seeds are sown in October-November (winter rainfed crop) or in February-March (irrigated crop). Higher seed rate is required for unirrigated crop. Seeds are sown in lines 30cm apart. Application of 5-10t of FYM/ha before planting or raising a green manure crop is beneficial. About 40kg N and 25-50kg P2O5/ha applied as basal dressing and 40kg N/ha applied in 2 split dozes as top dressing gave better yield. While the rainfed crop is grown without irrigation, the irrigated crop requires 5-8 light irrigations during the entire growing season. The crop requires 2-3 weedings and hoeings in order to keep it free from weeds. Alternaria alternata causes leaf spot and dieback but the disease is not serious. In North India, the plant is attacked by the larvae of butterfly Catopsilia pyranthe which can be controlled by planting the crop in March-April instead of June-July. Under irrigated conditions, the first crop is obtained after 90 days of planting. The leaves are stripped by hand when they are fully green, thick and bluish-green in colour. The second crop is taken 4 weeks after the first harvest and the third 4-6 weeks after the second one. The last harvest of leaves is done when the entire crop is harvested along with the pods. Yield under irrigated conditions is nearly1.4t of leaves and 150kg pods/ha and under unirrigated conditions is 500-600kg leaves and 80-100kg pods/ha. The leaves are dried in thin layers under shade so as to retain the green colour and the pods are hung for 10-12 days to get dried. The leaves and pods are cleaned, graded and marketed (Husain et al, 1993).

Properties and Activity: Leaves contain glucose, fructose, sucrose and pinnitol. Mucilage consists of galactose, arabinose, rhamnose and galacturonic acid. Leaves also contain sennoside-C(8,8’- diglucoside of rhein-aloe-emodin-dianthrone). Pods contain sennosides A and B, glycoside of anthraquinones rhein and chrysophanic acid. Seeds contain -sitosterol (Husain et al, 1992). Leaves and pods also contain 0.33% -sterol and flavonols-kaempferol, kaempferin, and iso-rhamnetin. Sennoside content of C. acutifolia is higher ranging from 2.5% to 4.5% as compared to C. angustifolia ranging from 1.5 % to 2.5%.

The purgative activity of Senna is attributed to its sennosides. The pods cause lesser griping than the leaves. Leaf and pod is laxative. The leaves are astringent, bitter, sweet, acrid, thermogenic, cathartic, depurative, liver tonic, anthelmintic, cholagogue, expectorant and febrifuge.... indian senna

Baliospermum montanum

Euphorbiaceae

San: Danti;

Hin: Danti;

Mal: Danti, Nagadanti;

Tam: Nakatanti;

Tel: Nelajidi

Importance: Danti or Nagadanti is a stout undershrub with numerous flowers. Root, which is the officinal part, is used in abdominal pain, constipation, calculus, general anasarca, piles, helminthic manifestations, scabies, skin disorders, suppurative ulcers and diseases caused by the morbidity of kapha and pitta. Root paste is applied to painful swellings and piles. Leaves cure asthma and seeds are used in snakebite (Kurup et al, 1979; Sharma, 1983). The drug forms an important constituent of preparations like Dantyarishta, Dantiharitakileham, Kaisoraguggulu gulika, etc.(Sivarajan et al, 1994).

Distribution: The plant is found throughout the sub-Himalayan tracts from Kashmir to Khasi Hills. It is common in West Bengal, Bihar and Central and Peninsular India.

Botany: Baliospermum montanum (Willd.) Muell-Arg. syn. B. axillare Bl., B. polyandrum Wt. belongs to the family Euphrobiaceae. It is a stout under-shrub 0.9-1.8m in height with herbaceous branches from the roots. Leaves are simple, sinuate-toothed, upper ones small, lower ones large and sometimes palmately 3-5 lobed. Flowers are numerous, arranged in axillary racemes with male flowers above and a few females below. Fruits are capsules, 8-13mm long and obovoid. Seeds are ellipsoid smooth and mottled (Warrier et al,1993).

Agrotechnology: The tropical plant is suited to almost all soils. It can be cultivated either as pure crop or intercrop. It is propagated vegetatively by cuttings. About 15-20cm long rooted cuttings are used for planting. Pits of size 50cm cube are to be taken at 3m spacing and filled with dried cowdung, sand and top soil and formed into a mound. On these mounds, rooted cuttings are to be planted at 2 cuttings/mound. Cuttings establish within one month. Weeding is to be carried out at this time. Application of organic manure after every 6 months is beneficial. Irrigation during summer months is preferable. The plant is not attacked by any serious pests or diseases. Roots can be collected at the end of second year. The roots are to be cut and dried in sun before marketing. The yield is about one tonne root/ha (Prasad et al,1997).

Properties and activity: Roots contain diterpenes, baliospermin, montanin, phorbol-12-deoxy-13-O-palmitate, phorbol-12-deoxy-16-hydroxy-13-O-palmitate and phorbol-12-deoxy-5 -hydroxy-13 – myristate (Ogura et al, 1978). Alcoholic extract of plant showed hypotensive activity in experimental animals (Bhakuni et al, 1971). Antilukaemic and cytotoxic activities have been demonstrated in the esters of both 12-deoxyphorbol and 12-deoxy-16-hydroxyphorbol, isolated from B. montanum (King-horn, 1979). The roots are acrid, thermogenic, purgative, antiinflammatory, anodyne, digestive, anthelmintic, diuretic, diaphoretic, rubefacient, febrifuge and tonic. Seed is purgative, stimulant, rubefacient and antidote for snakebite. Seed oil is antirheumatic. Leaf is antiasthmatic and wound healing. Root and seed oil is cathartic and antidropsical. Stem is anti-dontalgic.... nagadanti

Linn. Sweet.

Synonym: A. indicum G. Don.

Family: Malvaceae.

Habitat: Throughout the hotter parts of India. Found as a weed in the sub-Himalayan tract and other hills up to 1,200 m.

English: Country Mallow, Flowering Maples, Chinese Bell-flowers.

Ayurvedic: Atibalaa, Kankatikaa, Rishyaproktaa.

Unani: Kanghi, Musht-ul-Ghaul, Darkht-e-Shaan.

Siddha/Tamil: Thutthi.

Folk: Kanghi, Kakahi, Kakahiyaa.

Action: Dried, whole plant— febrifuge, anthelmintic, demulcent, diuretic, anti-inflammatory (in urinary and uterine discharges, piles, lumbago). Juice of the plant— emollient. Seeds—demulcent (used in cough, chronic cystitis), laxative. Leaves—cooked and eaten for bleeding piles. Flowers— antibacterial, anti-inflammatory. Bark—astringent, diuretic. Root— nervine tonic, given in paralysis; also prescribed in strangury.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of the root in gout, polyuria and haemorrhagic diseases.

The plant contains mucilage, tannins, asparagines, gallic acid and ses- quiterpenes. Presence of alkaloids, leucoanthocyanins, flavonoids, sterols, triterpenoids, saponins and cardiac glycosides is also reported.

Asparagine is diuretic. Gallic acid is analgesic. Mucilages act by reflex, loosen cough as well as bronchial tension. Essential oil—antibacterial, antifungal.

The drug exhibits immunological activity. It augments antibody in animals. EtOH (50%) extract of A. indicum ssp. guineense Borssum, synonym A. asiaticum (Linn.) Sweet, exhibits anticancer activity.

Related sp. include: Abutilon avicen- nae Gaertn., synonym A. theophrastii

Medic.; A. fruticosum Guill. et al.; A. hirtum (Lam.) Sweet, synonym A. graveolens Wt. and Arn.; A. muticum Sweet, synonym A. glaucum Sweet; and A. polyandrum Wight and Arn., synonym A. persicum (Burm. f.) Merrill (known as Naani-khapaat, Jhinaki- khapaat, Kanghi, Makhamali-khapaat and Khaajavani-khapaat, respectively, in folk medicine).

Dosage: Root—3-6 g powder. (API Vol I.)... abutilon indicum

(Willd.) DC.

Synonym: A sinuata (Lour.) Merrill; A. rugata (Lamk.) Ham.

Family: Mimosaceae.

Habitat: Tropical jungles throughout India, especially in the Deccan.

Ayurvedic: Saptalaa, Shitalaa, Saatalaa, Shrivalli, Kantvalli.

Unani: Shikaakaai, Kharunb Nabti.

Siddha/Tamil: Seekai, Sigakai.

Folk: Ban-Reethaa.

Action: Febrifuge, expectorant, emetic, spasmolytic, diuretic, antidiarrhoeal. Leaves—an infusion is given in malarial fever. Pods and seeds—decoction is used to remove dandruff (known as Shikaakaai), extensively used as a detergent. An ointment is used for skin diseases. Bark—extract is used in leprosy.

The bark yields a saponin which, on hydrolysis, yields lupeol, alpha- spinasterol and acacic acid lactone. Pods also yield saponins (20.8%). Sugars identified are glucose, arabinose and rhamnose.

The leaves contain alkaloids, nicotine and colycotomine, a triterpenoid saponin and oxalic, tartaric, citric, suc- cinic and ascorbic acids.

The bark saponins are spermicidal, also haemolytic and spasmolytic. A decoction of pods relieves biliousness and acts as a purgative.

The ethanolic extract of unripe pods yields a glycosidal fraction (0.28%) which exhibits anti-inflammatory activity. It also shows significant antibacterial activity.

The plant acts as an antiseptic agent for curing sores, gums and loose teeth.

The flowers are the source of Cassie perfume.

The main constituents of the flowers are benzyl, anisic, decylic and cuminic aldehydes, as well as traces of geraniol, farnesol and linalool.... acacia concinna

Linn.

Synonym: Manilkara zapota (Linn.) P. van Royan Manilkara achras (Mill.) Fosberg Sapota achras Mill.

Family: Sapotaceae.

Habitat: Native to Central America. Cultivated chiefly in Maharashtra, Tamil Nadu and West Bengal.

English: Sapota, Sapodilla Plum, Chicle.

Unani: Sapotaa, Cheeku.

Siddha/Tamil: Shimai eluppai.

Action: Fruit—antibilious. Seed— diuretic. Fruit and bark—febrifuge.

The bark contains latex (20-25% of which consists of gutta-percha-like substance); also contains tannin (11.8%). The seeds contain quercitol.

Chewing gum consists of approximately 20% chicle, plus sugar, corn syrup and flavourings.... achras zapota

Lindl.

Family: Bignoniaceae.

Habitat: Temperate Himalaya from Kashmir to Kumaon at 600-2700 m.

Folk: Kaur (Kashmir).

Action: Plant—febrifuge; used as a substitute for Swertia chirayita.

An iridoid glycoside named amph- icoside is reported from the plant.... amphicome emodi

Nees

Family: Acanthaceae.

Habitat: Warmer parts of India. Folk: Ranchimani (Maharashtra).

Action: Febrifuge, diuretic.

The plant contains a flavone, echio- dinin, and its glucoside, echioidin. EtOH (50%) extract of the plant exhibited diuretic activity in animal studies.... andrographis echioides

Dalz.

Synonym: A. barbata Baker Family: Papilionaceae; Fabaceae.

Habitat: Subtropical tract of Assam, Maharashtra and Kerala, up to 1050 m.

Ayurvedic: Maashaparni (substitute).

Siddha/Tamil: Peruvidukol.

Action: Febrifuge, antibilious, an- tirheumatic (used in consumption and swellings).... atylosia goensis

Wall. ex Royle.

Family: Ranunculaceae.

Family: Ranunculaceae.

Habitat: The alpine Himalayas from Sikkim to Garhwal and Assam.

English: Indian Aconite, Wolfsbane, Monkshood.

Ayurvedic: Vatsanaabha, Visha, Amrita, Vajraanga, Sthaavaravisha, Vatsanaagaka, Shrangikavisha, Garala.

Unani: Bish, Bishnaag.

Siddha/Tamil: Vasanaavi, Karunaab- hi.

Folk: Bacchanaag, Bish, Mithaa Zahar, Telia Visha.

Action: Narcotic, sedative, antilepro- tic, anti-inflammatory. Extremely poisonous. (Roots possess depressant activity, but after mitigation in cow's milk for 2-3 days, they exhibit stimulant activity.)

Key application: In neuralgia. (Aconitum napellus L. has been listed by German Commission E among unapproved herbs.)

The root contains diterpenoid alkaloids, which act as a powerful poison that affects the heart and central nervous system. Aconitine has a shortlived cardiotonic action followed by

Habitat: Cultivated at Manali and Rahla in Himachal Pradesh. Also found in northwestern Himalayas at altitudes ranging from 2,000 to 4,000 m.

English: Atis Root, Aconite.

Ayurvedic: Ativishaa, Arunaa, Vishaa, Shuklakandaa, Bhanguraa, Ghunapriyaa, Ghunavallabhaa, Kaashmiraa, Shishubhaishajyaa (indicating its use in paediatrics), Vishwaa.

Unani: Atees.

Siddha/Tamil: Athividayam.

Folk: Patis.

Action: Often regarded as non- poisosnous, antiperiodic, anti- inflammatory, astringent (used in cough, diarrhoea, dyspepsia), tonic (used after fevers), febrifuge, antispasmodic (used in irritability of stomach and abdominal pains).

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of the dried, tuberous root in emesis and helminthi- asis.

The roots yield 0.79% of total alkaloids, of which atisin is 0.4%. Atisine is much less toxic than aconitine and pseudoaconitine. (The inert character of the plant is well known to the hill people, who often use it as a vegetable.) The plant possesses potent immuno- stimulant properties.

Dosage: Root—0.6-2.08 g. (API Vol. I.)... aconitum heterophyllum

Nees.

Synonym: A. zeylanica Medic. Justicia adhatoda Linn.

Family: Acanthaceae.

Habitat: Throughout India, up to an altitude of 1,300 m.

English: Malabar Nut, Vasaca.

Ayurvedic: Vaasaa, Vaasaka, Vaasikaa, Simhaasya, Simhaparni, Simhavadanaa, Vaajidanta, Vrisha, Aataruushaka.

Unani: Arusaa.

Siddha/Tamil: Aadaathodai.

Folk: Vasaakaa.

Action: Expectorant (used in bronchial, asthmatic and pulmonary affections), antispasmodic, febrifuge.

Key application: As bronchodilatory, expectorant. (Indian Herbal Pharmacopoeia.) The Ayurvedic Pharmacopoeia of India indicates its use in dyspnoea.

The chief quinazoline alkaloid vas- icine is reported in all parts of the plant, the highest being in inflorescence. It is a bitter bronchodilator, respiratory stimulant, hypotensive, cardiac depressant, uterotonic and aborti- facient. An aqueous solution of va- sicinone hydrochloride, when studied in mice and dogs, was found to potentiate the bronchodilatory activity of aminophylline, also that of isopre- naline. Vasicinone exhibited smooth- muscle-relaxant properties of airways.

Alkaloids present in the plant showed significant protection against allergin-induced bronchial obstruction in guinea pigs.

The leaves are found to activate the digestive enzyme trypsin.

An extract of the leaves showed significant antifungal activity against ringworm.

Adhatoda beddomei C.B. Clarke, found in Kerala, is considered to be more powerful and active than A. vasi- ca. Fresh leaf juice is used in haemoptysis and menorrhagia, also as an antiasthmatic.

Jacobinia tinctoria Henl. is equated with the red-flowered var. of Vaasaa.

Dosage: Leaf—10-20 ml juice. Dried leaves—10-20 g for deoction. Root—3-6 g powder. (API Vols. I, IV)... adhatoda vasica

(L.) Benth.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India; up to 1,800 m in the western Himalayas.

Ayurvedic: Vana-kulattha.

Folk: Jangli Tur, Kulthi.

Action: Antidysenteric, anticholerin, febrifuge; also used in anaemia, anasarca and hemiplegia. Seeds— taeniafuge.

A flavone glucoside, atyloside, has been isolated from the leaves.... atylosia scarabaeoides

Cucurbitaceae

The family Cucurbitaceae includes a large group of plants which are medicinally valuable. The important genera belonging to the family are Trichosanthes, Lagenaria, Luffa, Benincasa, Momordica, Cucumis, Citrullus, Cucurbita, Bryonopsis and Corallocarpus. The medicinally valuable species of these genera are discussed below.

1. Trichosanthes dioica Roxb.

Eng: Wild Snake-gourd; San: Meki,Pargavi, Parvara, Patola;

Hin: Palval, Parvar

Ben: Potol;

Mal: Kattupatavalam, Patolam;

Tam: Kombuppudalai;

Tel: Kommupotta

Wild snake-gourd is a slender-stemmed, extensively climbing, more or less scabrous and woolly herb found throughout the plains of N. India, extending to Assam and W. Bengal. Tendrils are 2-4 fid. Leaves are 7.5x5cm in size, ovate-oblong, cordate, acute, sinuate- dentate, not lobed, rigid, rough on both surface and with a petiole of 2cm. Flowers are unisexual. Male flowers are not racemed but woolly outside. Calyx tube is 4.5cm long, narrow, teeth linear and erect. Anthers are free. Fruit is 5.9cm long, oblong or nearly spherical, acute, smooth and orange-red when ripe. Seeds are half-ellipsoid, compressed and corrugated on the margin (Kirtikar and Basu, 1988). The unripe fruit of this is generally used as a culinary vegetable and is considered very wholesome and specially suited for the convalescent. The tender shoots are given in decoction with sugar to assist digestion. The seeds are useful for disorders of the stomach. The leaf juice is rubbed over the chest in liver congestion and over the whole body in intermittent fevers (Nadkarni, 1998). The fruit is used as a remedy for spermatorrhoea. The fresh juice of the unripe fruit is often used as a cooling and laxative adjunct to some alterative medicines. In bilious fever, a decoction of patola leaves and coriander in equal parts is given. The fruit in combination with other drugs is prescribed in snakebite and scorpion sting (Kirtikar and Basu, 1988).

Fruits contain free amino acids and 5-hydroxy tryptamine. Fatty acids from seeds comprise elaeostearic, linoelic, oleic and saturated acids. The aerial part is hypoglycaemic. Leaf and root is febrifuge. Root is hydragogue, cathartic and tonic. Unripe leaf and fruit is laxative (Husain et al, 1992). The plant is alterative and tonic. Leaves are anthelmintic. Flower is tonic and aphrodisiac. The ripe fruit is sour to sweet, tonic, aphrodisiac, expectorant and removes blood impurities.

The other important species belonging to the genus Trichosanthes are as follows.

T. palmata Roxb. T. cordata Roxb. T. nervifolia Linn.

T. cucumerina Linn.

T. anguina Linn.

T. wallichiana Wight. syn. T. multiloba Clarke

2. Lagenaria vulgaris Ser. syn. Cucurbita Lagenaria Linn. ; Roxb.

Eng: Bottle gourd San: Alabu Hin: Lauki, Jangli-khaddu

Ben: Lau, Kodu

Mal: Katuchuram, Churakka

Tam: Soriai-kay

Tel: Surakkaya

Bottle gourd is a large softly pubescent climbing or trailing herb which is said to be indigenous in India, the Molucas and in Abyssinia. It has stout 5-angled stems with bifid tendrils. Leaves are ovate or orbiculate, cordate, dentate, 5-angular or 5-lobed, hairy on both surfaces. Flowers are large, white, solitary, unisexual or bisexual, the males long and females short peduncled. Ovary is oblong, softly pubescent with short style and many ovules. Fruits are large, usually bottle or dumb-bell-shaped, indehiscent and polymorphous. Seeds are many, white, horizontal, compressed, with a marginal groove and smooth. There are sweet fruited and bitter-fruited varieties (Kirtikar and Basu, 1988). The fruit contains a thick white pulp which, in the cultivated variety (kodu) is sweet and edible, while in the smaller wild variety (tamri) it is bitter and a powerful purgative. The seeds yield clear limpid oil which is cooling and is applied to relieve headache. The pulp of the cultivated forms is employed as and adjunct to purgatives and considered cool, diuretic and antibilious, useful in cough, and as an antidote to certain poisons. Externally it is applied as a poultice. The leaves are purgative and recommended to be taken in the form of decoction for jaundice (Nadkarni, 1998). In the case of sweet-fruited variety, the stem is laxative and sweet. The fruit is sweet oleagenous, cardiotonic, general tonic, aphrodisiac, laxative and cooling. In the case of bitter-fruited variety, the leaves are diuretic, antibilious; useful in leucorrhoea, vaginal and uterine complaints and earache. The fruit is bitter, hot, pungent, emetic, cooling, cardiotonic, antibilious; cures asthma, vata, bronchitis, inflammations ulcers and pains.

3. Luffa acutangula (Linn.) Roxb.

Eng: Ridged gourd; San: Dharmargavah, Svadukosataki;

Hin: Tori, Katitori;

Ben: Ghosha

Mal: Peechil, Peechinga;

Tam: Pikangai, Prikkangai;

Tel: Birakaya;

Kan: Kadupadagila

Ridged gourd or ribbed gourd is a large monoecious climber cultivated throughout India. It is with 5-angled glabrous stems and trifid tendrils. Leaves are orbicular-cordate, palmately 5-7 lobed, scabrous on both sides with prominent veins and veinlets. Flowers are yellow, males arranged in 12-20 flowered axillary racemes. Female flowers are solitary, arranged in the axils of the males. Ovary is strongly ribbed. Fruits are oblong-clavate with 10-sharp angles 15-30cm long, tapering towards the base. Seeds are black, ovoid-oblong, much compressed and not winged (Warrier et al, 1995). The leaves are used in haemorrhoids, leprosy, granular-conjunctivitis and ringworm. The seeds are useful in dermatopathy. The juice of the fresh leaves is dropped into the eyes of children in granular conjunctivitis, also to prevent the lids from adhering at night on account of excessive meihomian secretion (Nadkarni, 1998). Fruits are demulcent, diuretic, tonic, expectorant, laxative and nutritive. The seeds are bitter, emetic, cathartic, expectorant and purgative.

The other important species of the genus Luffa are:

L. aegyptiaca Mill.

L. acutangula var. amara Clarke

L. echinata Roxb.

4. Benincasa hispida (Thumb.) Cogn. syn. B. cerifera Savi.

Eng: Ash gourd, White gourd melon; San: Kusmandah;

Hin: Petha, Raksa;

Ben: Kumra

Mal: Kumpalam;

Tam: Pusanikkai;

Kan: Bile Kumbala;

Tel: Bodigummadi

Ash gourd or White gourd melon is a large trailing gourd climbing by means of tendrils which is widely cultivated in tropical Asia. Leaves are large and hispid beneath. Flowers are yellow, unisexual with male peduncle 7.5-10cm long and female peduncle shorter. Fruits are broadly cylindric, 30-45cm long, hairy throughout and ultimately covered with a waxy bloom. The fruits are useful in asthma, cough, diabetes, haemoptysis, hemorrhages from internal organs, epilepsy, fever and vitiated conditions of pitta. The seeds are useful in dry cough, fever, urethrorrhea, syphilis, hyperdipsia and vitiated conditions of pitta (Warrier et al,1993). It is a rejuvenative drug capable of improving intellect and physical strength. In Ayurveda, the fresh juice of the fruit is administered as a specific in haemoptysis and other haemorrhages from internal organs. The fruit is useful in insanity, epilepsy and other nervous diseases, burning sensation, diabetes, piles and dyspepsia. It is a good antidote for many kinds of vegetable, mercurial and alcoholic poisoning. It is also administered in cough, asthma or respiratory diseases, heart diseases and catarrah. Seeds are useful in expelling tapeworms and curing difficult urination and bladder stones. The important formulations using the drug are Kusmandarasayana, Himasagarataila, Dhatryadighrita, Vastyamantakaghrita, Mahaukusmandakaghrita, etc. (Sivarajan et al, 1994).

Fruits contain lupeol, -sitosterol, n-triacontanol, vitamin B, mannitol and amino acids. The fruit is alterative, laxative, diuretic, tonic, aphrodisiac and antiperiodic. Seed and oil from seed is anthelmintic (Husain et al, 1992).

5. Momordica charantia Linn.

Eng: Bitter gourd, Carilla fruit San: Karavellam

Hin: Karela, Kareli

Mal: Kaypa, Paval

Tam: Pavakkai, Paval, Pakar

Tel: Kakara

Bitter gourd or Carilla fruit is a branched climbing annual which is cultivated throughout India. It is a monoecious plant with angled and grooved stems and hairy or villous young parts. Tendrils are simple, slender and elongate. Leaves are simple, orbicular, cordate and deeply divided into 5-7 lobes. Flowers are unisexual, yellow and arranged on 5-10cm long peduncles. Fruits are 5-15cm long with 3-valved capsules, pendulous, fusiform, ribbed and beaked bearing numerous triangular tubercles. Seeds are many or few with shining sculptured surface. The roots are useful in coloptosis and ophthalmopathy. The leaves are useful in vitiated conditions of pita, helminthiasis, constipation, intermittent fever, burning sensation of the sole and nyctalopia. The fruits are useful in skin diseases, leprosy, ulcers, wounds, burning sensation, constipation, anorexia, flatulence, colic, helminthiasis, rheumatalgia, gout, diabetes, asthma, cough, dysmenorrhoea, impurity of breast milk, fever and debility. Seeds are useful in the treatment of ulcers, pharyngodynia, and obstructions of the liver and spleen. The leaves and fruits are used for external application in lumbago, ulceration and bone fractures and internally in leprosy, haemorrhoids and jaundice (Warrier et al, 1995). The drug improves digestion, calms down sexual urge, quells diseases due to pitta and kapha and cures anaemia, anorexia, leprosy, ulcers, jaundice, flatulence and piles. Fruit is useful in gout, rheumatism and complaints of liver and spleen (Nadkarni, 1954; Aiyer and Kolammal, 1966; Mooss, 1976; Kurup et al, 1979). Kaccoradi taila is an important preparation using the drug (Sivarajan et al, 1994).

The seeds give triterpene glycosides, named momordicosides A, B, C, D and E, which are glycosides of cucurbit-5-en-triol, tetraol or pentaol. Leaves and vines give tetracyclic triterpenes-momordicines I, II and III (bitter principles). Immature fruits give several non-bitter and 2 bitter cucurbitacin glycosides. Four of the non-bitter glycosides, momordicosides F1, F2, G and I and the bitter momordicosides; K and L have also been characterized. Fruits, seeds and tissue culture give a polypeptide which contained 17 types of amino acids and showed hypoglycaemic activity. Fruits also give 5-hydroxy tryptamine and a neutral compound charantin (a steroidal glucoside), diosgenin, cholesterol, lanosterol and -sitosterol. Leaf is emetic, purgative and antibilious. Fruit is stomachic, tonic, carminative, febrifuge, antirheumatic and hypoglycaemic. Root is astringent. Fruit and leaf is anti-leprotic. Fruit, leaf and root are abortifacient and anti-diabetic. Leaf and seed is anthelmintic. Seed oil possesses antifeeding and insecticidal properties. Unsaponifiable matter from seed oil exhibited pronounced inhibitory activity against gram negative bacteria. Seed and fruit are hypoglycaemic, cytotoxic and anti-feedant (Husain et al, 1992).

Other important species belonging to the genus Momordica are as follows.

M. dioica Roxb.

M. cochinchinensis Spreng.

M. tuberosa Cogn.

M. balsamina Linn.

6. Cucumis melo Linn. syn. C. melo Linn. var. cultis Kurz., C. pubescens

Willd., C. callosus (Rottl.) Cogn.

Eng: Sweet melon San,

Hin: Kharbuja

Ben: Kharmul

Mal: Mulam

Tam: Chukkari-kai, Thumatti-kai, Mulampazham

Tel: Kharbuja-doshavSweet melon is a creeping annual extensively cultivated throughout India, found wild in India, Baluchistan and tropical Africa. The stem is creeping, angular and scabrous. Leaves are orbicular-reniform in outline, 5-angled or lobed, scabrous on both surfaces and often with soft hairs. Lobes of leaves are not very deep nor acute and with 5cm long petiole. Female peduncle is 5cm. Fruit is spherical, ovoid, elongate or contorted, glabrous or somewhat hairy, not spinous nor tuberculate.

Cucumis melo includes two varieties, namely,

C. melo var. momordica syn. C. momordica Roxb.

C. melo var. utilissimus Duthie & Fuller. syn. C. utilissimus Roxb.

The fruit is eaten raw and cooked. Its pulp forms a nutritive, demulcent, diuretic and cooling drink. It is beneficial as a lotion in chronic and acute eczema as well as tan and freckles and internally in cases of dyspepsia. Pulp mixed with cumin seeds and sugar candy is a cool diet in hot season. Seeds yield sweet edible oil which is nutritive and diuretic, useful in painful discharge and suppression of urine. The whole fruit is useful in chronic eczema (Kirtikar & Basu, 1988).

Seeds contain fatty acids-myristic, palmitic, oleic, linoleic; asparagine, glutamine, citrulline, lysine, histidine, arginine, phenylalanine, valine, tyrosine, leucine, iso-leucine, methionine, proline, threonine, tryptophan and crystine. Seed is tonic, lachrymatory, diuretic and urease inhibitor. Fruit pulp is eczemic. Fruit is tonic, laxative, galactagogue, diuretic and diaphoretic. The rind is vulnerary (Husain et al, 1992).

7. Cucumic sativus Linn.

Eng: Cucumber, Common cucumber; San: Trapusah;

Hin,

Ben: Khira;

Mal: Vellari

Tam: Vellarikkai, Pippinkai;

Kan: Mullusavte;

Tel: Dosekaya

Cucumber is a climbing annual which is cultivated throughout India, found wild in the Himalayas from Kumaon to Sikkim. It is a hispidly hairy trailing or climbing annual. Leaves are simple, alternate, deeply cordate, 3-5 lobed with both surfaces hairy and denticulate margins. Flowers are yellow, males clustered, bearing cohering anthers, connective crusted or elevated above the cells. Females are solitary and thickly covered with very bulbous based hairs. Fruits are cylindrical pepo of varying sizes and forms. Seeds are cream or white with hard and smooth testa. The fruits are useful in vitiated conditions of pitta, hyperdipsia, burning sensation, thermoplegia, fever, insomnia, cephalgia, bronchitis, jaundice, haemorrhages, strangury and general debility. The seeds are useful in burning sensation, pitta, constipation, intermittent fevers, strangury, renal calculus, urodynia and general debility (Warrier et al, 1994). The leaves boiled and mixed with cumin seeds, roasted, powdered and administered in throat affections. Powdered and mixed with sugar, they are powerful diuretic (Nadkarni, 1998). The fruits and seeds are sweet, refrigerant, haemostatic, diuretic and tonic. Other important species belonging to the genus are:

C. trigonus Roxb. syn. C. pseudo-colocynthis

C. prophetarum Linn.

8. Citrullus colocynthis (Linn.) Schrader. syn. Cucumis colocynthis Linn.

Eng: Colocynth, Bitter apple; San: Visala, Mahendravaruni;

Hin: Badi indrayan, Makkal

Ben: Makhal;

Mal: Kattuvellari (Valutu), Valiya pekkummatti;

Tel: Etti-puchcha

Tam: Paitummatti, Petummatti;

Colocynth or Bitter apple is found, cultivated and wild, throughout India in warmer areas. It is an extensively trailing annual herb with bifid tendrils angular branching stems and wooly tender shoots. Leaves are deeply divided, lobes narrow thick, glabrous or somewhat hairy. Flowers are unisexual, yellow, both males and females solitary and with pale-yellow corolla. Fruit is a globose or oblong fleshy indehiscent berry, 5-7.5cm in diameter and variegated with green and white. Seeds are pale brown. The fruits are useful in tumours, ascites, leucoderma, ulcers, asthma, bronchitis, urethrorrhea, jaundice, dyspepsia, constipations, elephantiasis, tubercular glands of the neck and splenomegaly (Warrier et al, 1994). It is useful in abnormal presentations of the foetus and in atrophy of the foetus. In addition to the above properties, the root has a beneficial action in inflammation of the breasts, pain in the joints; externally it is used in ophthalmia and in uterine pains. The fruit and root, with or without is rubbed into a paste with water and applied to boils and pimples. In rheumatism, equal parts of the root and long pepper are given in pill. A paste of the root is applied to the enlarged abdomen of children (Kirtikar and Basu, 1988). The fruit is useful in ascites, biliousness, jaundice, cerebral congestion, colic, constipation dropsy, fever, worms and sciatica. Root is given in cases of abdominal enlargement, cough, asthma, inflammation of the breast, ulcers, urinary diseases and rheumatism. Oil from seeds is used for poisonous bites, bowel complaints, epilepsy and also for blackening the hair (Nadkarni, 1954; Dey, 1980). The important formulations using the root and fruit are Abhayarista, Mahatiktakam kasaya, Manasamitravatakam, Cavikasava, Madhuyastyadi taila, etc. (Sivarajan et al, 1994). The powder is often used as an insecticide. The extract should never be given without some aromatic to correct its griping tendency (Nadkarni, 1998).

Fruit contains a glycoside- colocynthin, its aglycone- -elaterin, citrulluin, citrullene and citrullic acid. Unripe fruit contains p-hydroxy benzyl methyl ester. Roots contain - elaterin and hentriacontane (Husain et al, 1992). Colocynth is, in moderate doses, drastic, hydrogogue, cathartic and diuretic. In large doses, it is emetic and gastro-intestinal irritant and in small doses, it is expectorant and alterative. Colocynthin is a cathartic and intensely bitter principle. It has a purgative action. All parts of the plant are very bitter. The fruit has been described as cathartic (Nadkarni, 1982).

9. Citrullus vulgaris Schrad. syn. C. lanatus (Thunb.) Mats. & Nakai.

Eng: Water melon; San: Tarambuja;

Hin: Tarbuj;

Ben: Tarbuz

Mal: Thannimathan;

Tam: Pitcha, Dharbusini

Watermelon is an extensively climbing annual which is largely cultivated throughout India and in all warm countries. It has thick angular branching stems. Tendrils are bifid, stout and pubescent. Leaves are long, deeply divided or moderately lobed, glabrous or somewhat hairy and hardly scabrous. Petiole is a little shorter than the limb and villous. Calyx-lobes are narrowly lanceolate, equalling the tube. Corolla is yellow within, greenish outside and villous. Lobes are ovate-oblong, obtuse and prominently 5-nerved. Fruit is sub-globose or ellipsoid, smooth, greenish or clouded, often with a glaucous waxy coating. Flesh is juicy, red or yellowish white. Seeds are usually margined. C. vulgaris var. fistulosus Duthie & Fuller. syn. C. fistulosus has its fruit about the size of small turnip, the seeds of which are used medicinally. The fruit is tasteless when unripe and sweet when ripe. The unripe fruit is used to cure jaundice. Ripe fruit cures kapha and vata and causes biliousness. It is good for sore eyes, scabies and itching. The seeds are tonic to the brain and used as a cooling medicine. An emulsion of the seeds is made into a poultice with the pounded leaves and applied hot in cases of intestinal inflammations (Kirtikar and Basu, 1988). Fruit juice is good in quenching thirst and it is used as an antiseptic in typhus fever with cumin and sugar. It is used as a cooling drink in strangury and affections of urinary organs such as gonorrhoea; in hepatic congestion and intestinal catarrh. The bitter watermelon of Sind is known as “Kirbut” and is used as a purgative.

Seeds yield a fixed oil and proteids; citrullin. Seeds are cooling, demulcent, diuretic, vermifuge and nutritive. Pulp is cooling and diuretic. Fruit-juice is cooling and refreshing (Nadkarni, 1982).

10. Curcurbita pepo Linn. syn. Pepo vulgaris et P. verrucosus Moench

Meth.

Eng: Pompion, Pumpkin, Vegetable Marrow; San: Karkaru, Kurkaru, Kushmandi

Hin,

Ben: Kadimah, Konda, Kumra, Safedkkadu;

Mal: Mathan, Matha

Tel: Budadegummadi, Pottigummadi

Pompion or Pumpkin is a climbing herb which is considered to be a native of America and cultivated in many parts of India. The stem and leaves are with a harsh prickly armature. Foliage is stiff, more or less rigid and erect. Leaves are with a broad triangular pointed outline and often with deep lobes. Corolla is mostly with erect or spreading (not drooping) pointed lobes, the tube narrowing towards the base. Peduncle is strongly 5-angled and little or much expanding near the fruit. The fruit is cooling and astringent to the bowels, increases appetite, cures leprosy, ‘kapha and vata’, thirst, fatigue and purifies the blood. The leaves are used to remove biliousness. Fruit is good for teeth, throat and eyes and allays thirst. Seeds cure sore chests, haemoptysis, bronchitis and fever. It is good for the kidney and brain. The leaves are used as an external application for burns. The seeds are considered anthelmintic. The seeds are largely used for flavouring certain preparations of Indian hemp, and the root for a nefarious purpose, viz., to make the preparation more potent. The seeds are taeniacide, diuretic and demulcent. The fruit is cooling, laxative and astringent. The leaves are digestible, haematinic and analgesic.

The other important species belonging to the genus Cucurbita is C. maxima Duchena, the seeds of which are a popular remedy for tape-worm and oil as a nervine tonic (Kirtikar & Basu, 1988).

11. Corallocarpus epigaeus Benth. ex Hook. f. syn. Bryonia epigaea Wight.

San: Katunahi;

Hin: Akasgaddah;

Mal: Kadamba, Kollankova

Tam: Akashagarudan, Gollankovai;

Tel: Murudonda, Nagadonda

Corallocarpus is a prostrate or climbing herb distributed in Punjab, Sind, Gujarat, Deccan, Karnataka and Sri Lanka. It is monoecious with large root which is turnip-shaped and slender stem which is grooved, zigzag and glabrous. Tendrils are simple, slender and glabrous. Leaves are sub-orbicular in outline, light green above and pale beneath, deeply cordate at the base, angled or more or less deeply 3-5 lobed. Petiole is long and glabrous. Male flowers are small and arranged at the tip of a straight stiff glabrous peduncle. Calyx is slightly hairy, long and rounded at the base. Corolla is long and greenish yellow. Female flowers are usually solitary with short, stout and glabrous peduncles. Fruit is stalked, long, ellipsoid or ovoid. Seeds are pyriform, turgid, brown and with a whitish corded margin. It is prescribed in later stages of dysentery and old veneral complaints. For external use in chronic rheumatism, it is made into a liniment with cumin seed, onion and castor oil. It is used in case of snakebite where it is administered internally and applied to the bitten part. The root is given in syphilitic rheumatism and later stages of dysentery. The plant is bitter, sweet, alexipharmic and emetic. The root is said to possess alterative and laxative properties (Kirtikar and Basu, 1988). Root contains a bitter principle like Breyonin (Chopra et al, 1980).

Agrotechnology: Cucurbits can be successfully grown during January-March and September- December. For the rainfed crop, sowing can also be started after the receipt of the first few showers.

Pits of 60cm diameter and 30-45cm depth are to be taken at the desired spacing. Well rotten FYM or vegetable mixture is to be mixed with topsoil in the pit and seeds are to be sown at 4-5/pit. Unhealthy plants are to be removed after 2 weeks and retained 2-3 plants/pit. FYM is to be applied at 20-25t/ha as basal dose along with half dose of N (35kg/ha) and full dose of P (25kg) and K (25kg). The remaining dose of N (35kg) can be applied in 2 equal split doses at fortnightly intervals. During the initial stages of growth, irrigation is to be given at an interval of 3-4 days and at alternate days during flowering and fruiting periods. For trailing cucumber, pumpkin and melon, dried twigs are to be spread on the ground. Bitter gourd, bottle gourd, snake gourd and ash gourd are to be trailed on Pandals. Weeding and raking of the soil are to be conducted at the time of fertilizer application. Earthing up may be done during rainy season. The most dreaded pest of cucurbits is fruit flies which can be controlled by using fruit traps, covering the fruits with polythene, cloth or paper bags, removal and destruction of affected fruits and lastly spraying with Carbaryl or Malathion 0. 2% suspension containing sugar or jaggery at 10g/l at fortnightly intervals after fruit set initiation. During rainy season, downy mildew and mosaic diseases are severe in cucurbits. The former can be checked by spraying Mancozeb 0.2%. The spread of mosaic can be checked by controlling the vectors using Dimethoate or Phosphamidon 0.05% and destruction of affected plants and collateral hosts. Harvesting to be done at least 10 days after insecticide or fungicide application (KAU,1996).... cucurbits

Curcuma spp.

Zingiberaceae

The genus Curcuma belonging to the family Zingiberaceae comprises of a number of species which are medicinally very important. Among them, the most important species are described below.

1. C. amada Roxb.

English: Mango ginger San: Amrardrakam, Karpuraharida Hin: Ama -haldi

Mal: Mangainchi

Tam: Mankayinci

Tel: Mamidi Allam

Mango ginger is cultivated in Gujarat and found wild in parts of West Bengal, U. P, Karnataka and Tamil Nadu. It is a rhizomatous aromatic herb with a leafy tuft and 60-90cm in height. Leaves are long, petiolate, oblong-lanceolate, tapering at both ends, glabrous and green on both sides. Flowers are white or pale yellow, arranged in spikes in the centre of tuft of the leaves. Lip is semi -elliptic, yellow, 3-lobbed with the mid lobe emarginate. The rhizomes are useful in vitiated conditions of pitta, anorexia, dyspepsia, flatulence, colic, bruises, wounds, chronic ulcers, skin diseases, pruritus, fever, constipations, strangury, hiccough, cough, bronchitis, sprains, gout, halitosis, otalgia and inflammations (Warrier et al, 1994). The fresh root possesses the smell of green mango and hence the name mango ginger. The rhizomes are used externally in the form of paste as an application for bruises and skin diseases generally combined with other medicines. Tubers rubbed with the leaf- juice of Caesalpinia bonduc is given for worms (Nadkarni, 1982).

The essential oil contains -pinene, -and -curcumene, camphor, cuminyl alcohol, myristic acid and turmerone. Car-3-ene and cis-ocimene contribute the characteristic mango odour of the rhizome. Rhizome is CNS active, hypothermic and it shows potentiation of amphetamine toxicity. Tuber is trypsin inhibitor and is effective against Vibrio cholerae (Husain et al, 1992). The rhizomes are bitter, sweet sour, aromatic, cooling, appetiser, carminative, digestive, stomachic, demulcent, vulnerary, febrifuge, alexertic, aphrodisiac, laxative, diurectic, expectorant, antiinflammatory and antipyretic (Warrier et al, 1994).

2. C. aromatica Salisb.

Eng: Wild turmeric; San: Aranyaharidra, Vanaharidra;

Hin: Ban-haridra, Jangli-haldi;

Ben: Ban Haland; Mal,

Tam: Kasturimanjal, Kattumanjal;

Tel: Adavi-pasupu;

Kan: Kadarasina

Wild turmeric or Cochin turmeric or Yellow zeodoary is found wild throughout India and cultivated in Bengal and Kerala. It is a perennial tuberous herb with annulate, aromatic yellow rhizome which is internally orange-red in colour. Leaves are elliptic or lanceolate- oblong, caudate-acuminate, 30-60cm long, petioles as long or even longer, bracts ovate, recurved, more or less tinged with red or pink. Flowers are pink, lip yellow, obovate, deflexed, sub-entire or obscurely three lobed. Fruits are dehiscent, globose, 3-valved capsules. Rhizomes are used in combination with astringents and aromatics for bruises, sprains, hiccough, bronchitis, cough, leucoderma and skin eruptions (Warrier et al, 1994). The rhizomes have an agreeable fragrant smell and yield a yellow colouring matter like turmeric, and the fresh root has a camphoraceous odour. The dried rhizome is used as a carminative and aromatic adjunctant to other medicines (Nadkarni, 1998).

Essential oil contains -and - -curcumene, d-camphene and p-methoxy cinnamic acid. The colouring matter is curcumin. Numerous sesquiterpenoids of germacrone and guaiane skeletons have been identified recently. Rhizome has effect on respiration. It is spasmolytic and shows antagonism of amphetamine hyperactivity. Rhizome is an anti-dote for snakebite and carminative (Husain et al, 1992).

3. C. longa Linn. syn. C. domestica Valeton.

Eng: Turmeric; San: Haridra, Varavarnini;

Hin: Haldi, halda;

Ben: Haldi;

Mal: Manjal, Pachamanjal, Varattumanjal;

Tam: Mancal;

Kan: Haldi, Arasina;

Tel: Pasapu

Turmeric is cultivated all over India, particularly in W. Bengal, T. N and Maharashtra. It is a perennial herb, 60-90cm in height, with a short stem and tufts of erect leaves. Rhizome is cylindric, ovoid, orange coloured and branched. Leaves are simple, very large, petiole as long as the blade, oblong-lanceolate, tapering to the base upto 45cm long. Flowers are pale yellow, arranged in spikes concealed by the sheathing petioles and flowering bracts are pale green (Warrier et al, 1994). Turmeric occupies an important position in the life of Indian people as it forms an integral part of the rituals, ceremonies and cuisine. Due to the strong antiseptic properties, turmeric has been used as a remedy for all kinds of poisonous affections, ulcers and wounds. It gives good complexion to the skin and so it is applied to face as a depilatory and facial tonic. The drug cures diseases due to morbid vata, pitta and kapha, diabetes, eye diseases, ulcers, oedema, anaemia, anorexia, leprosy and scrofula. It purifies blood by destroying the pathogenic organisms. A paste of turmeric alone, or combined with a paste of neem (Azadirachta indica) leaves, is used to cure ringworm, obstinate itching, eczema and other parasitic skin diseases and in chicken pox and small pox. The drug is also useful in cold, cough, bronchitis, conjunctivitis and liver affections (Nadkarni, 1954; Kurup et al,1979; Kolammal, 1979). The rhizome is the officinal part and is an important ingredient of formulations like Nalpamaradi taila, Jatyadi taila, Narayana gula, etc. (Sivarajan et al, 1994).

Turmeric paste mixed with a little limejuice and saltpetre and applied hot is a popular application to sprains and bruises. In smallpox and chickenpox, a coating of turmeric is applied to facilitate the process of scabbing. The smoke produced by sprinkling powdered turmeric over burnt charcoal will relieve scorpion sting when the part affected is exposed to the smoke for a few minutes. Turmeric and alum powder in the proportion of 1:20 is blown into the ear in chronic otorrhoea (Nadkarni, 1998). “Haridra Khand”, a compound containing powdered turmeric, sugar and many other ingredients is a well-known preparation for cold, cough and flu, and for skin diseases. In Unani system, roasted turmeric is an ingredient of “Hab Narkachur”, used as antidysenteric for children (Thakur et al, 1989).

Essential oil contains ar-turmerone, and ar-curcumene as ma jor constituents. Some of the other compounds are -and -pinene, sabinene, myrcene, -terpinene, limonene, p- cymene, perillyl alcohol, turmerone, eugenol, iso-eugenol, eugenol methyl ether and iso- eugenol methyl ether. Curcumin and related compounds have also been reported as major constituents of the rhizomes. Recently a number of sesquiterpenes have been reported from C. longa, viz., the sesquiterpenoids of germacrane, bisabolane and guainane skeletons (Husain et al, 1992). The study of sesquiterpenes has revealed a new compound curlone (Kisoy et al, 1983). The crystalline colouring matter curcumin (0. 6%) is diferuloyl methane (Mathews et al, 1980). Stigmasterol, cholestrol, -sitosterol and fatty acids, mainly straight chain dienoic acids are reported (Moon et al, 1977). Curcumin, the colouring agent and major constituent of C. longa, is said to possess local as well as systemic antiinflammatory property which has been found to compare favourably with phenylbutazone (Srimal and Dhawan, 1973). An extract of the crude drug ‘akon’ containing the rhizomes exhibited intensive preventive activity against carbon tetrachloride induced liver injury invivo and invitro. The liver protecting effects of some analogs of ferulic acid and p-coumaric acid, probable metabolites of the curcuminoids have been also evaluated (Kiso et al, 1983). Curcumin is antiinflammatory. Rhizome is antiprotozoal, spasmolytic, CNS active, antiparasitic, antispasmodic, antibacterial, antiarthritic, anthelmintic, carminative, antiperiodic, emo llient, anodyne, laxative, diruretic, expectorant, alterative, alexertive, febrifuge, opthalmic and tonic.

4. C. zedoaria (Berg.) Rosc. syn. C. zerumbet Roxb; Amomum zedoaria

Christm.vEng: Round zedoary; San: Kachura, Shati;

Hin: Kakhur;

Ben: Sati;

Kan: Kachora

Mal: Manjakoova, Adavi-kacholam;

Tam: Kichilikizhangu, Nirvisham;

Tel: Kacheramu

The round zedoary or Zerumbet is mostly found in India and S. E. Asia. The plant has 4-6 leaves with 20-60cm long lamina. The leaf lami na is oblong-lanceolate, finely acuminate and glabrous on both the surfaces. Flower stalk is 20-25cm long, emerging before the leaves. Flowers are yellow, while the flowering bract is green tinged with red. Calyx is 8mm long, corolla tube is twice as long as the calyx. Capsule is ovoid, trigonous, thin smooth and bursting irregularly. Tubers are palmately branched and camphoraceous (Thakur et al, 1989). The identity of the plant sources of the drug Karcura is a matter of debate. There is difference of opinion among men of Ayurveda, as to whether Sati and Karcura are the same drug or different. Many authors consider them different and equate Sati with Hedychium spicatum Smith. and Karcura with C. zedoaria, both belonging to Zingiberaceae (Kurup et al,1979; Chunekar 1982; Sharma, 1983). Some others treat them to be the same and equate it with C. zedoaria (Kirtikar and Basu, 1918; Vaidya, 1936; Nadkarni, 1954; Kapoor and Mitra, 1979). However, the source of Karcura in Kerala in the recent times has been Kaempferia galanga of the same family. The rhizome of C. zedoaria is used as appetiser and tonic, particularly prescribed to ladies after childbirth. In case of cold, a decoction of long pepper (Piper longum), cinnamon (Cinnamomum verum), zedoary and honey is given. In Ayurveda it is an ingredient of “Braticityadi kwatha”, used in high fever (Thakur et al, 1989). Root is useful in flatulence and dyspepsia, and as a corrector of purgatives. Fresh root checks leucorrhoeal and gonorrhoeal discharges. Root powder is a good substitute for many foreign foods for infants. For worms, the juice from the tubers is given to children. Juice of the leaves is given in dropsy (Nadkarni, 1982). It is an odoriferous ingredient of the cosmetics used for the cure of chronic skin diseases caused by impure or deranged blood (Nadkarni, 1998).

Essential oil from rhizomes contains -pinene, d-camphene, cineole, d-camphor, sesquiterpenes and sesquiterpene alcohols (Husain et al, 1992). The novel sesquiterpenoids which have been isolated and characterised are cuzerenone, epi-cuzerenone, iso- furanogermerene, curcumadiol, curcumol, curcumenol, iso-curcumenol, procurcumenol, dehydrocurdione (Hikino et al, 1968, 1971, 1972), germacrone-4, 5-epoxide, germacrone, germacrone furanodienone, curcumenol, iso-curcumenol, curcumanolides A and B and curcumenone (Shiobara et al, 1985). The starch left after the extraction is purified and sold as a commodity of cottage industry in West-Bengal under the name ‘Shoti’ (Rao et al, 1928). Ethyl-p methoxy-cinnamate has been isolated from the alcoholic extract of the plant (Gupta et al, 1976). Rhizome is stomachic, diuretic, and carminative and gastrointestinal stimulant.

Other important species of Curcuma genus are

C. angustifolia Roxb. (Vellakoova)

C. caesia Roxb. (Black ginger)

C. leucorhiza Roxb.

C. pseudomontana Grah.

C. rubescens Roxb.

Agrotechnology: Curcuma species are tropical herbs and can be grown on different types of soils both under irrigated and rainfed conditions. Rich loamy soils having good drainage are ideal for the crop. The plant is propagated by whole or split mother rhizomes. Well developed, healthy and disease free rhizomes are to be selected. Rhizomes are to be treated with copper oxychloride fungicides and stored in cool, dry place or earthen pits plastered with mud and cowdung. The best season of planting is during April with the receipt of pre-monsoon showers. The land is to be prepared to a fine tilth during February-March. On receipt of pre- monsoon showers in April, beds of size 3x1.2m with a spacing of 40cm between beds are to be prepared. Small pits are to be taken in the beds in rows with a spacing of 25-40cm.

Finger rhizomes are to be planted flat with buds facing upwards and covered with soil or dry powdered cattle ma nure. The crop is to be mulched immediately after planting and 50 days after first mulching. Cattle manure or compost is to be applied as basal dose at 20-40t/ha at the time of land preparation or by spreading over the beds after planting. Application of NPK fertilizers is beneficial and found to increase the yield considerably. Weeding is to be done twice at 60 and 120 days after planting, depending upon weed intensity. Earthing up is to be done after 60 days. No major incidence of pest or disease is noticed in this crop. Leaf blotch and leaf spot can be controlled by spraying Bordeaux mixture or 0.2% Mancozeb. Shoot borers can be controlled by spraying 0.05% Dimethoate or 0.025% Quinalphos. Time of harvest usually extends from January-March. Harvesting is generally done at about 7-10 months after planting depending upon the species and variety. Harvested rhizomes are to be cleaned of mud and other materials adhering to them. Good fingers separated are to be used for curing (KAU, 1996).... curcuma

Datura metel

Solanaceae

San: Dhustura Hin.: Kaladhatura

Ben: Dhatura Mal: Ummam Kan; Dattura

Tam: Vellummattai

Tel: Tellavummetta

Importance: Downy datura or thorn apple is an erect branched under shrub whose intoxicating and narcotic properties have been made use of by man from ancient time. The plant and fruit are spasmolytic, anticancerous and anthelmintic. Leaves and seeds are inhaled in whooping cough, asthma and other respiratory diseases. Root, leaf and seed are febrifuge, antidiarrhoeal, anticatarrhal and are used in insanity, cerebral complications and skin diseases. Leaf is antitumour, antirheumatic and vermicide. Flower is antiasthamatic, anaesthetic and is employed in swellings and eruptions on face. Fruit juice is used in earache and seed decoction in ophthalmia. For the rheumatic swellings of joints, lumbago, sciatica and neuralgia, warm leaf smeared with an oil is used as a bandage or sometimes the leaf is made into a poultice and applied. The root boiled with milk is used in insanity. It is also an ingredient in the ayurvedic preparation Kanakasva used in bronchial troubles, and the Unani formulations “Roghan dhatura” used as a massage oil for the paralysed part. The alkaloids of pharmaceutical interest present in the plant are hyoscyamine, hyoscine and meteloidine. Datura is the chief commercial source of hyoscine available from natural source. Hyoscine, in the form of hyoscine hydrobromide, is used as a pre-anaesthetic in surgery, child birth, ophthalmology and prevention of motion sickness. It is also employed in the relief of withdrawal symptoms in morphine and alcoholic addiction, paralysis agitans, post- encephaletic parkinsonianism and to allay sexual excitement. Hyoscyamine and its salt hyoscyamine sulphate and hyoscyamine hydrobromide are used in delerium, tremour, menia and parkinsonianism (Kaul and Singh, (1995).

Distribution: Datura is distributed throughout the world, particularly the warmer regions. Datura stramonium is indigenous to India. Out of 15 species reported from different parts of the world, only 10 are known to occur in India. They are found commonly in wastelands, gardens and roadsides. They are distributed in rich localities under semi -arid and arid regions of Punjab, Haryana, Rajastan, and Gujarat; the Central Plateau of Andhra Pradesh and Maharastra and the southern peninsular region of Tamil Nadu. Datura innoxia is indigenous to Mexico and is distributed in Latin American countries. A wealth of genetic stock on genotypes and varieties are maintained in several research institutes in Germany, Bulgaria, USSR and Poland.

Botany: The genus Datura, belonging to the family solanaceae, consists of annual and perennial herbs, shrubs and trees. Three species,viz, Datura metel Linn., D. stramonium Linn. and D. innoxia Mill. are medicinally important. D. innoxia mill. and D. metel Linn. (var. alba, and var, fastuosa) are the choice drug plants, rich in hyoscine. D. metel Linn. is the most common in India. The names, D. metel Linn., D. fastuosa Linn., D. alba Nees., D. fastuosa Linn. var. alba (Nees) C.B. Clarke and D. metel Linn. var. fastuosa (Linn.) Safford are synonymously used by many workers. Two varieties are often noted in D. metel Linn., namely the white flowered var. alba and purple flowered var. fastuosa. D. metel Linn. is an erect succulent branched undershrub divaricate often purplish branches and ovate pubescent leaves which are oblique at the base of lamina. Flowers are large, solitary, short pedicelled, purplish outside and white inside. Fruits are sub-globose capsules covered all over with numerous, fleshy prickles, irregularly breaking when mature. Seeds are numerous, smooth, yellowish brown. (warrier et al, 1994).

Agrotechnology: Datura grows well in a wide range of climate from tropical to temperate conditions.

The plant thrives best in areas of low rainfall where winter and monsoon rains are followed by long dry periods. Areas with annual rainfall below 1000mm with mean temperature of 10-15oC in winter and 27 - 28oC in May-June are ideal. The crop cannot stand frost, high rainfall or high temperature in the plains in May-June. It grows on majority of soils, however, alkaline or neutral clay loam soil or those tending to saline-alkaline reaction rich in organic matter are ideal for vigorous growth. The clayey, acidic, water-logged or moisture deficient soils do not suit this crop.

The plant is propagated by seeds but it is characterised by poor and often erratic seed germination which can be improved either by leaching out the inhibitor from the seeds or by alternate freezing and thawing of seeds. The optimum season for raising the crop is Rabi in tropical and subtropical areas while Kharif in temperate areas. The seeds can be broadcast - sown or seedlings can be raised in nursery and then transplanted. Seed rate is 7-8 kg/ha for broadcasting and 2-3 kg/ha. for transplanting. The field is ploughed and disced adequately to produce fine seed bed. In the case of direct seeding, seeds are drilled in rows taken 45-60 cm apart. The plants are thinned to keep a spacing of 30-45 cm at the time of first weeding. In the case of transplanting 4-6 weeks old seedlings are planted at 45-60 x 30-45 cm spacing. The field should be irrigated immediately after sowing or planting if soil moisture is inadequate. Thereafter 3-4 irrigations may be given if sufficient rainfall is not received. Application of organic manure at 10-15 t/ha and fertilisers at 60:40:40 kg N, P2O5 and K2O/ha is recommended for the crop for better growth and yield N may be applied in 3-4 equal split doses at planting and after each weeding which is required 2-3 times during the growing season. Application of micronutrients is reported to improve the alkaloid contents. No major insect pest is known to attack this crop. However, leaf spot, wilt and mosaic diseases cause damage to this crop. Leaf spot is caused by Alternaria tennuissima (Nees) Wiltshire and characterised by brown round to oval spots, becoming necrotic at later stage which leads to withering and dropping of leaves. Wilt is caused by Sclerotium rolfsii Sace; it starts with dropping of leaves and finally wilting of the entire plant. Root and foot wilt, caused by Corticium solani, appears as damping off of seedlings and mature plants. Datura distortion mosaic is characterised by yellowing of the veins followed by inward rolling and distortion of leaves with a reduction in plant size. For reducing the impact of these diseases, field sanitation, use of resistant varieties, crop rotation for 3-4 years and fungicide application should be resorted to. For the purpose of leaf and top, harvesting is done as soon as flowering starts. Entire top containing leaves and twigs is cut, dried in shade and stored in gunny bags. For seed and fruit, fully grown fruits, still green are picked 2-3 times before final harvest when the entire plant is cut from the base and dried in the open. The dried fruits are then thrashed with a stick to separate the seeds. The seed yield is 1-1.5 t/ha. (Husain, 1993; Kaul and Singh, 1995)

Properties and activity: The alkaloids hyoscyamine and hyoscine (scopolamine) and meteloidine are found in all parts of the plant. The total alkaloid content is 0.26 - 0.42 % Fruits contain daturaolone and daturadiol while roots contain additionally ditigloyloxy tropane derivatives, tigloidine, apohyoscine, norhyoscine, norhyocyamine, cusiohygrine and tropine. Other alkaloids isolated from the plant are apohyoscyamine, DL-scopolamine, normeteloidine, tigloylputrescine, scopine, nortigloidine, tropine, psuedo valeroidine, fastudine, fastunine, fastusinine, 7-hydroxy-3, 6-ditigloyloxytropane (2) datura nolone and fastusic acid. The physiological effects of hyoscyamine are qualitatively the same as those of its recemic derivative atropine. This is relatively more active in its paralysing affect on nerve endings and less active in its stimulant action on the central nervous system. The sedative and hypnotic action of hyoscyamine is weaker than that of hyoscine. Atropine has a stimulant action on the central nervous system and depresses the nerve endings to the secretary glands and plain muscles. The plant or the different alkaloids have narcotic, anthelmintic, spasmolytic anaesthetic, sedative, ophthalmic, anticancerous, antitumour, antirheumatic, antiasthmatic, antidiarrhoeal and anticatarrhal activities. (Thakur et al, 1989).... datura

Cass.

Family: Compositae; Asteraceae.

Habitat: Native to Africa and Asia, found in north-western and southern India.

Folk: Navananji (Maharashtra), Vajradanti (Punjab).

Action: Febrifuge (used in febrile attacks after childbirth. Applied locally to putrescent wounds.

In Indian medicine, Vajradanti, equated with Potentilla arbuscula D. Don and its related species (Rosaceae), is used topically for strengthening gums and teeth.... dicoma tomentosa

Hook. f. ex Brandis

Family: Rubiaceae.

Habitat: Indigenous in deciduous forests all over India.

English: Yellow Teak, Saffron Teak.

Ayurvedic: Haridru, Haraduaa- kadamba, Gaur-kadamba, Girikadamba, Dhaaraakadam- ba, Pitadaaru, Kadambapushpa.

Siddha/Tamil: Manjakadambu.

Folk: Haladu, Kheta Kadam.

Action: Antibacterial, antiseptic, antidysenteric, antibilious (used in biliary colic), febrifuge. Root— astringent.

The heartwood contains indole alkaloids; bark 7.27-9.27% tannin. The leaves contain ursolic acid and querce- tin.... adina cordifolia

Linn.

Family: Hippocastanaceae; Sapinda- ceae.

Habitat: Endemic to the mountains of Balkan Peninsula and western Asia. Introduced into India; occasionally grown as an ornamental tree.

English: Horse Chestnut tree.

Unani: Baloot. (Quercus incana and Q. infectoria have also been equated with Baloot in National Formulary in Unani Medicine.)

Folk: Pu.

Action: Anti-inflammatory, vasodilator, astringent (used for rheumatism, venous congestion, haemorrhoids), febrifuge. Leaf— used in whooping cough.

Key application: In chronic venous insufficiency, varicosis, nocturnal systremma (cramps in the calves) and swelling of the legs. (Non- invasive treatment measures should also be followed.) (German Commission E, ESCOP, The British Herbal Pharmacopoeia.)

Horse Chestnut contains triterpe- noid saponins (especially aescin, a complex mixture composed of acylat- ed glycosides of protoaesigenin and barringtogenol-C, including hippo- caesculin), coumarins and flavonoids. Aescin has been shown to eliminate oedema and reduce exudation. It antagonizes the effect of bradykinin, although it is not a direct bradykinin antagonist. It causes an increase in plasma levels of ACTH, corticosterone and glucose in rats. Hippocaescu- lin and barringtogenol-C-21-angelate show antitumour activity in vitro.

The hydroxycoumarin aesculin leads to increased bleeding time. (Roasting seems to destroy the toxins.) A few fruits can cause severe toxic symptoms. (Francis Brinker.) In some countries, an intravenous mixture containing aescin is used after surgery. (Natural Medicines Comprehensive Database, 2007.)... aesculus hippocastanum

(Rosc.) K. Schum.

Synonym: Amomum melegueta Rosc.

Family: Zingiberaceae.

Habitat: Native to tropical Africa; cultivated in Indian gardens.

English: Grains of Paradise, Alligator pepper, Meleguetta pepper.

Unani: Heel Habshi.

Action: Roots possess cardamomlike tasteand aregivenasadecoction for constipation; also as a vermifuge for tapeworms. Juice of young leaves—styptic. The seeds contain an alkaloid, piperine; also gingerol, paradol, shogaol and zingerone.

Gingerol and shogaol suppress gastric contractions; also have sedative and analgesic actions. Pungency of the grains is due to paradol.

A decoction of the whole plant is taken internally as a febrifuge.

High oxalic acid content in the fruit may cause reduced function of the heart.

Aframomum korarima K. Schum., native to tropical Africa, known as... aframomum melegueta

Roxb.

Family: Simaroubaceae.

Habitat: Bihar, Madhya Pradesh, Gujarat, Orissa and southern India.

English: Tree of Heaven, Maharukh.

Ayurvedic: Aralu, Katvanga, Dirghavranta, Puutivrksha, Bhallu- ka. (Mahaanimba is a synonym of Melia azedarach Linn.)

Siddha: Perru, Perumaruttu, Peruppi.

Action: Bark—bitter, astringent, febrifuge, anthelminitic, antispas- modic, expectorant (used in asthma, bronchitis). Also used for dysentery as a substitute for Holarrhena antidysenterica.

Bark and leaves—used as tonic in debility, especially after childbirth. Leaves—used as adulterant for Ad- hatoda zeylanica leaves.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of stembark in high fevers and giddiness.

The bark contains several quassi- noids including ailanthone derivatives. They exhibit antitumour activity against P-388 lymphocytic leukaemia and are cytotoxic against KB test system.

Dosage: Stembark—1-3 g (API Vol. III.) Decoction—50-100 ml. (CCRAS.)... ailanthus excelsa

(Roxb.) Nees.

Family: Acanthaceae.

Habitat: Hills of Deccan Peninsula and parts of western and central India.

Folk: Kaalaa-Kirayaat (Maharashtra).

Action: Febrifuge, bitter tonic.

A closely related species, Haplan- thus tentaculatus Nees, is also known as Kaalaa-Kiryaat. The herb is given in fever.... haplanthus verticillatus

(Burm. f) Moore.

Family: Adiantaceae.

Habitat: Plains and mountains of South India up to 1,200., and in West Bengal, Bihar and Orissa.

English: Mule Fern.

Folk: Raamabaanam (Andhra Pradesh), Chakuliya (Bengal).

Action: Fonds—antibacterial, used in burns and as febrifuge.

Heracleum candicans Wall. ex DC.... hemionites arifolia

DC.

Synonym: A. triphysa (Dennst.) Alston.

Family: Simaroubaceae.

Habitat: The evergreen forests of western Ghats from Konkan southwards.

Siddha: Perumaram.

Folk: Guggul-dhuupa. (Maharashtra.)

Action: Bark—febrifuge, carminative (given in typhoid, dyspepsia and constipation). Oleo resin— used for dysentery and bronchitis.

The bark and roots give a number of beta-carboline alkaloids. The resin- uous exudates from trunk give several triterpenoids, including malabaricol and malabaricanediol.... ailanthus malabarica

Linn.

Family: Linaceae.

Habitat: Konkan and North Kanara, throughout dry forests of Tamil Nadu.

Folk: Kaakibeeraa, Kansamaara.

Siddha/Tamil: Agori. Motirakkanni.

Action: Root—anti-inflammatory, febrifuge; disperses swellings.... hugonia mystax

Roxb.

Family: Malvaceae.

Habitat: Common in sub- Himalayan tract.

Folk: Pola, Pulu, Pula, Polao. Vendi (Tamil Nadu). Potri, Konda Potari, Pandiki, Pachabotuka (Andhra Pradesh). Velukku, Venta, Nedunar (Kerala).

Action: Plant—mucilaginous, antiinflammatory, febrifuge. Leaf and root—antirheumatic. The leaves stimulate saliva. A paste of leaves is applied in body pains, used in poultices for skin diseases.... kydia calycina

R. Br.

Family: Apocynaceae.

Habitat: Throughout moist regions of India, especially in West Bengal and west-coast forests of southern India.

English: Devil's tree, Dita Bark tree.

Ayurvedic: Saptaparna, Sapta- chhada, Saptaparni, Saptaahvaa, Vishaaltvak, Shaarada, Visham- chhada.

Unani: Chhaatim, Kaasim (Kaasim Roomi, Anjudaan Roomi is equated with Myrrhis odorata Scope.)

Siddha/Tamil: Ezhilamippalai, Mukkampalai.

Folk: Chhitavan, Sataunaa.

Action: Bark—febrifuge, antiperi- odic, spasmolytic, antidysenteric, uterine stimulant, hypotensive; used for internal fevers.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of stembark in phosphaturia and recommends it as a blood purifier.

Alstonia sp. is known as Fever Bark. A. constricta is native to Australia; A. scholaris to Australia and Southeast Asia. The bark of both the species contains indole alkaloids. A. constric- ta contains reserpine (a hyptotensive agent). A. scholaris contains echita- mine, which has also demonstrated hypotensive effects. Though A. schol- aris produces fall in the temperature of human patients with fever, there are conflicting reports about the activity of echitamine against Plasmodium berghei.

Dosage: Stembark—20-30 g for decoction. (API Vol. I.)... alstonia scholaris

(Linn.) R. Br. ex DC.

Synonym: A. triandra Lam. A. denticulata R. Br. A. repens Gmel. Non-Link.

Family: Amaranthaceae.

Habitat: Throughout the hotter parts of India, especially around tanks and ponds.

Ayurvedic: Matsyaakshi, Matsyaak- shika (a multimeaning name, also indicating Braahmi, Ain- dri), Matsyagandhaa, Matsyaa- dini, Minaakshi, Bahli, Gandali, Gartkalambukaa, Vaahlikaa.

Unani: Machhechhi.

Siddha/Tamil: Ponnonkanni keerai.

Folk: Gudari Saag.

Action: Febrifuge, galactagogue, cholagogue.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of dried whole plant in diseases due to vitiated blood and obstinate skin diseases.

Young shoots contain protein 5% and iron 16.7 mg/100 g. Leaves also contain a good amount of alpha- and beta-tocopherols.

The plant gave stigmasterol, beta- sitosterol, a saturated aliphatic hydrocarbon and aliphatic ester.

Dosage: Whole plant—2-6 g powder. (API Vol. II.)... alternanthera sessilis

Kuntze

Synonym: Volutarella divaricata Benth. and Hook. F.

Family: Compositae; Asteraceae.

Habitat: Distributed in the Mediterranean region, extending to Central Asia and India.

Ayurvedic: Brahmadandi (Tri- cholepis glaberrima DC. of the same family is also equated with Brahmadandi.)

Unani: Baadaavard.

Action: Deobstruent, aperient, febrifuge, nervine (used in debility), antiseptic (used in leucoderma).... amberboa divaricata

Linn.

Family: Lythraceae.

Habitat: Marshy areas throughout India, as a weed.

English: Blistering Ammannia.

Ayurvedic: Agnipatri.

Folk: Daadmaari. (Also known as Paashaanabheda.)

Action: Stomachic, laxative, antirheumatic, febrifuge. Leaves— used externally for ringworm, herpic eruptions and other skin diseases; rubefacient.

Leaves contain lawsone. Plant extract—antibacterial. Extracts of stem, leaf and inflorescence are more effective as compared with the seed and root extract.... ammannia baccifera

Linn.

Family: Lythraceae.

Habitat: Native to China; grown as an ornamental.

English: Common Crape Myrtle.

Siddha/Tamil: Pavalak-kurinji, Sinappu.

Folk: Saavani, Faraash.

Action: Seed—narcotic. Bark— stimulant, febrifuge. Leaves and flowers—purgative. Root— astringent. Used as a gargle.... lagerstroemia indica

(L.) Griseb.

Synonym: Menyanthes indica Linn. Nymphoides indicum (L.) O. Kuntze.

Family: Menyanthaceae.

Habitat: Throughout India, in tanks and back waters.

Folk: Barachuli, Chinnambal (Kerala).

Action: Plant—bitter, febrifuge, antiscorbutic. Used as a substitute for Swertia Chirata in fever and jaundice.... limnanthemum indicum

Cav.

Family: Malvaceae.

Habitat: Throughout greater part of India.

Siddha/Tamil: Sithamutti, Mammat- ti, Peraamutti.

Action: Plant—purgative, an- thelmintic, febrifuge.

The stem gave a saponin, pavo- phylline, and a keto-ester, methyl 19- ketotetracosanoate.... pavonia zeylanica

Linn.

Family: Anacardiaceae.

Habitat: Native to tropical America, from Mexico to Peru and Brazil. Cultivated largely in Malabar, Kerala, Karnataka, Tamil Nadu and Andhra Pradesh, and to some extent in Maharashtra, Goa, Orissa and West Bengal.

English: Cashew Nut.

Unani: Kaaju.

Siddha/Tamil: Mindiri.

Action: Leaves and bark—fungi- cidal, vermicidal, protozoicidal, antimicrobial (used for toothache, sore gums). Karnel—eaten for its high protein content. Cashew apple—antiscorbutic. Resinous juice contained in the seeds—used in cases of mental derangement, memory disturbances, palpitation of heart, rheumatic pericarditis, sexual debility.

The nut contains 45% fat and 20% protein. Leaves contain flavonoids, mainly glycosides of quercetin and kaempferol, and hydroxybenzoic acid. The bark contains a balsam-containing anacardic acid, anacardol, cardol and ginkgol. The caustic liquid in the shell contains about 39% anacardic acid, a mixture of alkyl salicylic acid derivatives. The leaves are febrifuge. Anacardic acid is bactericidal, fungici- dal, vermicidal and protozoicidal. The leaves and bark exhibited hypotensive activity in rats.

The phenolics of the cashew-nut shell oil have inhibited the enzymic activity of alpha-glucosidase, invertase and aldose reductase (anacardic acids being the most potent). Cardols have also shown antifilarial activity in vitro. Anacardic acids, cardols and methyl cardols have been found to exhibit moderate cytotoxic activity.... anacardium occidentale

Wall. ex Nees

Family: Acanthaceae.

Habitat: Throughout India, from Himachal Pradesh to Assam and Mizoram, and all over southern India.

English: Creat.

Ayurvedic: Kaalmegha, Bhuunimba, Bhuuminimbaka, Vishwambharaa, Yavtikta, Kalpanaatha, Kiraata-tikta (var.).

Unani: Kiryaat.

Siddha/Tamil: Nilavembu.

Action: Hepatoprotective, cholin- ergic, antispasmodic, stomachic, anthelmintic, alterative, blood purifier, febrifuge. It acts well on the liver, promoting secretion of bile. Used in jaundice and torpid liver, flatulence and diarrhoea of children, colic, strangulation of intestines and splenomegaly; also for cold and upper respiratory tract infections.

Key application: As bitter tonic, febrifuge and hepatoprotective. (Indian Herbal Pharmacopoeia.)

Kaalmegha, officinal in IP, consists of dried leaves and tender shoots, which yield not less than 1% andro- grapholide on dry-weight basis.

Several active constituents have been identified from the leaf and rhizome, including andrographolide, deoxyan- drographolide and other diterpenes.

Andrographolide exhibited strong choleretic action when administered i.p. to rats. It induces increase in bile flow together with change in physical properties of bile secretion. It was found to be more potent than sily- marin.

Andrographolide was found to be almost devoid of antihepatitis-B virus surface antigen-like activity (when compared with picroliv.)

The leaf and stem extracts of Kaal- megha/andrographolide given s.c. or orally did not change blood sugar level of normal or diabetic rats.

Alcoholic extract of the plant exhibited antidiarrhoeal activity against E. coli enterotoxins in animal models.

Clinical evidence of effectiveness of andrographis in humans is limited to the common cold. Preliminary evidence suggests that it might increase antibody activity and phagocytosis by macrophages, and might have mast cell-stabilizing and antiallergy activity. (Natural Medicines Comprehensive Database, 2007.)

The herb is contraindicated inbleed- ing disorders, hypotension, as well as male and female sterility (exhibited infertility in laboratory animals).

Dosage: Whole plant—5-10 ml juice; 50-100 ml decotion; 1-3 g powder. (CCRAS.)... andrographis panicultata

Retz.

Synonym: Vetiveria zizanioides (Linn.) Nash.

Family: Poaceae.

Habitat: All over India.

English: Vetiver, Cuscus.

Ayurvedic: Ushira.

Unani: Khas.

Siddha: Vettiveru.

Action: Roots—refrigerant, febrifuge, diaphoretic, stimulant, stomachic and emmenagogue; used in strangury, colic, flatulence, obstinate vomiting; paste used as a cooling application in fevers.

Major constituents of the essential oil are vetiselinenol and khusimol. Several sesquiterpenoids, including vetid- iol, are also present. The two types of oils, laevorotatory and dextrorotatory, from northern India and southern India, respectively, are biochemically different.

Andropogon sp.: see Cymbopogon sp.... andropogon muricatus

Linn.

Family: Sterculiaceae.

Habitat: A shrub cultivated as an ornamental throughout the hotter parts of India.

Ayurvedic: Bandhujiva, Bandhuuka, Arkavallabha.

Folk: Gul-dupahariaa.

Action: Capsule—mucilaginous, used for the diseases of the bowels; a decoction is used as emollient. Root—astringent, antibilious, antiphlegmonous, febrifuge.... pentapetes phoenicea

Boiss.

Family: Salicaceae.

Habitat: Sub-Himalayan tracts from Uttar Pradesh westwards ascending to an altitude of 1,800 m.

Ayurvedic: Jala-vetasa.

Action: Bark—febrifuge.... salix acmophylla

Lesch.

Anthocephalus cadamba Miq.

Synonym: A. indicus A. Rich. A. chinensis (Lam.) A. Rich. ex Walp.

Family: Rubiaceae.

Habitat: Assam, Bengal, southwards to Andhra Pradesh and western Ghats.

English: Kadam.

Ayurvedic: Kadamba, Priyaka, Vrtta-pushpa, Nipa, Halipriya. Kadambaka is equated with Adina cordifolia.

Siddha/Tamil: Venkadambu, Vellai Kadambam.

Action: Stembark—febrifugal, antidiuretic, anthelmintic, hypo- glycaemic. Fruit—cooling; anti- catarrhal, blood purifier, analgesic.

Family: Moraceae.

Habitat: Western Ghats from Konkan southwards to Trivandrum, up to 600 m.

English: Sacking tree, Upas tree.

Ayurvedic: Valkala vrksha.

Siddha/Tamil: Aranthelli, Mara-uri, Nettavil.

Folk: Jangali Lakuch, Jasund, Chaandakudaa.

Action: Seed—febrifuge, antidysen- teric (in minute doses). Latex— circulatory stimulant (in minute doses.)

The latex contains a series of poisonous cardenolides, of which alpha- and/or beta-antiarin are the main components. The total amount of crystalline cardiac glycosides in the latex ranges from 0.1 to 2.5%; alpha-antiarin from 0.0 to 1.38% and beta-antiarin from 0.075 to 1.44%. Antiarins are said to act on the heart more powerfully than digitalin. Beta-antiarin is more potent than alpha-antiarin.

Latex, in small quantities, is a mild cardiac and circulatory stimulant, whereas in large quantities it acts as a myocardial poison. It stimulates intestinal and uterine contractions.

As many as 34 Kedde-positive substances were reported in the seed sample from Indonesia. The latex sample showed the presence of 29 Kedde- positive substances.... antiaris toxicaria

Linn.

Family: Oxalidaceae; Averrhoaceae.

Habitat: Native to Malaysia; cultivated throughout the warmer parts of India, especially in Kerala.

English: Carambola, Star Fruit, Chinese Gooseberry.

Ayurvedic: Karmaranga.

Unani: Khamraq, Karmal.

Siddha/Tamil: Tamarattai.

Folk: Kamarakh.

Action: Root—antidote in poisoning. Leaf and shoot—applied externally in ringworm, scabies, chickenpox. Flower—vermicidal. Fruit—laxative, antidysenteric, antiphlogistic, febrifuge, anti- inflammatory, antispasmodic (used in hepatic colic, bleeding piles). Seeds—galactogenic; in large doses act as an emmenagogue and cause abortion.

The fruits are a fairly good source of iron but deficient in calcium. They also contain oxalic acid and potassium oxalate. The presence of fluorine is also reported. A wide variation of vitamin-C content (0.3-23.0 mg/100 g) is recorded from different places in India. Sugar (3.19%) consists mainly of glucose (1.63%).... averrhoa carambola

(L.) Voss.

Synonym: B. arundinaceae (Retz.) Roxb.

Arundo bambos L.

Family: Gramineae; Poaceae.

Habitat: Wild throughout India, especially in the hill forests of Western and Southern India.

English: Spiny or Thorny Bamboo.

Ayurvedic: Vansha, Venu, Kichaka, Trinadhwaj, Shatparvaa, Yavphala. Vanshalochana, Vansharochanaa, Shubhaa, tugaa, Tugaakshiri, Tvak- kshiri (Bamboo-manna). Starch of Curcuma angustifolia Roxb., Zingiberaceae, was recommended a substitute for Vanshalochana (Ayurvedic Formularly of India, Part I, First edn).

Unani: Qasab, Tabaashir (Bamboo- manna).

Siddha/Tamil: Moongil; Moongilup- pu, (Bambo-manna.)

Action: Leaf bud and young shoots—used in dysmenorrhoea; externally in ulcerations. Leaf—em- menagogue, antileprotic, febrifuge, bechic; used in haemoptysis. Stem and leaf—blood purifier (used in leucoderma and inflammatory conditions). Root—poisonous. Burnt root is applied to ringworm, bleeding gums, painful joints. Bark—used for eruptions. Leaf and Bamboo-manna—emmena- gogue. Bamboo-manna—pectoral, expectorant, carminative, cooling, aphrodisiac, tonic (used in debilitating diseases, urinary infections, chest diseases, cough, asthma).

The plant gave cyanogenic glu- coside—taxiphyllin. Bamboo-manna contains silicious crystalline substances.

The starch obtained from Maranta arundinacea Linn., Marantaceae, is also used as Bamboo-manna (known as Koovai Kizhangu, Kookaineer and Araroottu Kizangu in Siddha medicine).

Dosage: Manna—1-3 g (CCRAS.)... bambusa bambos

Solanum spp.

Solanaceae

Solanums comprise a very important group of medicinal plants having multifarious uses.

These plants belong to the family Solanaceae and genus Solanum. A number of species are reported to be medicinal which are briefly described below.

1. S. anguivi Lam. syn. S. indicum auct. non Linn.

Eng: Poison berry; San: Brhati, Simhi;

Hin: Barhauta, Birhatta;

Mal: Puthirichunda, Cheruchunda;

Tam: Karimulli, Puthirichundai;

Kan: Ramagulla;

Tel: Cittimulaga, Tellamulaka It is found throughout the tropics, in plains and at low elevations. It is much branched, very prickly undershrub, 0.3-1.5m in height. Leaves are simple, large, ovate, subentire, sinuate or lobed. Flowers are blue in extra-axillary cymes having stellately hairy and prickly peduncles. Fruits are globose berries, reddish or dark yellow with smooth or minutely pitted seeds. Its roots are useful in vitiated conditions of vata and kapha, odontalgia, dyspepsia, flatulence, colic, verminosis, diarrhoea, pruritus, leprosy, skin diseases, strangury, cough, asthma, bronchitis, amenorrhoea, dysmenorrhoea, fever, cardiac disorders and vomiting. Roots bitter, acrid, astringent, thermogenic, anodyne, digestive, carminative, anthelmintic, stomachic, constipating, resolvent, demulcent, depurative, diuretic, expectorant, aphrodisiac, emmenagogue, febrifuge and cardiotonic.

2. S. dulcamara Linn.

Eng: Bittersweet, Bitter night shade; San: Kakmachi; Pun: Rubabarik It is found in tropical situations in India and Sikkim. The plant is rich in alkaloidal glycosides like solamarine, tomatidenol, solasodine and soladulcine. The berry and twig are alterative, antisyphilitic, diaphoretic, resolvent, narcotic, diuretic, antirheumatic and used in liver disorders and psoriasis.

3. S. erianthum D. Don, syn. S. verbascifolium auct. non Linn.

San: Vidari;

Hin: Asheta;

Mal: Malachunda;

Tam: Malaichundai, Anaisundaikkai

Pun: Kalamena;

Tel: Rasagadi

The plant is distributed over the tropical and subtropical zones of India. The plant contains alkaloids and steroidal sapogenins. Leaves and fruits contain solasodine, solasodiene, solafloridine, diosgenin, vespertilin and pregnenolone. The plant is CNS depressant, antiinflammatory and useful in burns.

4. S. melongena Linn.

Eng: Brinjal, Egg plant; San: Varttaki;

Hin: Bengan, Badanjan;

Mal: Vazhuthina

Tam: Kattirikkai;

Kan: Badanekaya, Doddabadane;

Tel: Vankaya, Niruvanga

It is mainly cultivated as a vegetable throughout the tropics and subtropics. It is an erect or suffrutescent, herbaceous, armed or unarmed perennial shrub. Leaves are simple, large, entire and lobed. Flowers are blue, in clusters of 2-5. Fruits are large, white, yellow or dark purple berries of different shapes capped with thick persistent calyx. Seeds are many, yellow or cream and discoid. The roots, leaves and unripe fruits are useful in cholera, bronchitis, asthma, odontalgia and fever. The roots are laxative, analgesic and cardiotonic. Leaves are sialagogue, narcotic and antiherpetic. The unripe fruits are bitter, acrid, sweet, aphrodisiac, cardiotonic and haematinic.

5. S. melongena var. incanum (Linn.) Prain syn. S. incanum Linn., S. coagulens Forsk.

San: Brihati;

Hin: Baigan;

Mal: Cheruvazhuthina

It is a herbaceous prickly plant found in warm humid tropics. It is grown almost throughout the year in the plains and during summer on the hills. It grows 0.6-2m in height. Leaves are simple, alternate lobed. Flowers are blue or white, 5 lobed, calyx with spines. Fruits are ellipsoid berries. The plant is a constituent of the dasamoola which helps to overcome vitiated tridoshas and cures dyspepsia, fever, respiratory and cardiac disorders, skin ailments, vomiting, ulcers and poisonous affections. In Ayurveda the formulations like Brihatyadi Kashaya, dashamoolarishta, Indukantaghritam, Dasamoolaharithaki, etc are the important preparations with the roots. It is also used in the treatment of toothache and sore throat. The fruit is reported to stimulate the intrahepatic metabolism of cholesterol. Roots are antiasthmatic and stimulant. Leaves are used in cholera, bronchitis and asthma. Fruits are useful in liver complaints.

6. S. nigrum Linn. syn. S. rubrum Mill.

Eng: Black night shade; San: Kakamachi;

Hin: Makoy, Gurkkamai;

Mal: Karimthakkali;

Tam: Manathakkali, Milagutakkali;

Kan: Kakarndi;

Tel: Kamachi, Kachi

It is seen wild throughout India. It is an erect, divaricately branched, unarmed, suffrutescent annual herb. Leaves are ovate or oblong, sinuate-toothed or lobed and glabrous. Flowers are 3-8 in extra-axillary drooping subumbellate cymes. Fruits are purplish black or reddish berries. Seeds are many, discoid, yellow, minutely pitted. The whole plant is useful in vitiated conditions of tridosha, rheumatalgia, swellings, cough, asthma, bronchitis, wounds, ulcers, flatulence, dyspepsia, strangury, hepatomegaly, otalgia, hiccough, opthalmopathy, vomiting, cardiopathy, leprosy, skin diseases, fever, splenomegaly, haemarrhoids, nephropathy, dropsy and general debility. The plant is bitter, acrid, emollient, antiseptic, antiinflammatory, expectorant, anodyne, vulnerary, digestive, laxative, diuretic, cardiotonic, depurative, diaphoretic, febrifuge, rejuvenating, sedative, alterant and tonic.

7. S. spirale Roxb.

Hin: Munguskajur

It is seen wild in Assam and Khasi hills in India. Its root is diuretic and narcotic.

8. S. stramoniifolium Jacq., syn. S. ferox auct. non Linn.

San: Garbhada;

Hin: Rambaigan;

Mal: Anachunda;

Tam: Anaichundai;

Tel: Mulaka

It is observed in India in the states of Assam, Maharashtra, Karnataka and Tamil Nadu. Its berries contain glycoalkaloids such as solasonine and solasodine. Its roots and berries are bechic, antiasthmatic, antirheumatic, antiviral, anticancerous and spermicidal.

9. S. surattense Burm. F. syn. S. xanthocarpum schrad. & Wendl., S. jacquinii Willd.

Eng: Yellow-berried nightshade; San: Kantakari, Nidigdhika;

Hin: Remgani,Kateli;

Mal: Kantakarichunda;

Tam: Kantankattiri;

Kan: Nelagulli;

Tel: Callamulaga

It is found throughout India and Pakistan in dry situations as weed on roadsides and wastelands. It is prickly, diffuse, bright green, suffrutescent, perennial undershrub, with zigzag branches. Leaves are ovate-oblong, hairy on both sides and armed on the midrib and the nerves. Flowers are bluish purple, in extra-axillary cymes. Fruits are glabrous, globular drooping berry, yellow or white with green veins, surrounded by the calyx. Seeds are many, small, reniform, smooth and yellowish brown.

The whole plant is useful in vitiated conditions of vata and kapha, helminthiasis, dental caries, inflammations, flatulence, constipation, dyspepsia, anorexia, leprosy, skin diseases, hypertension, fever, cough, asthma, bronchitis, hiccough, lumbago, haemorrhoids and epilepsy. The plant is bitter, acrid, thermogenic, anthelmintic, antiinflammatory, anodyne, digestive, carminative, appetiser, stomachic, depurative, sudorific, febrifuge, expectorant, laxative, stimulant, diuretic, rejuvenating, emmenagogue and aphrodisac. Fruits contain solasonine, solamargine and solasodine.

10. S. torvum Sw.

Eng: West Indian Turkey Berry;

Hin,

Ben: Titbaigan;

Mal: Kattuchunda;

Kan: Kadu Sunde;

Tam: Sundaikai, Amarakai;

Tel: Kundavustic, Kotuvestu; Ass: Hathibhekuri

It is seen throughout tropical India, particularly in Orissa, Bihar and Manipur. The plant is CVS active and used in splenomegaly. Fruits and leaves contain solasonine, solasodine, jurubine, jurubidine, torvonin, torvogenin, chlorogenin, paniculogenin, sisalogenone, neosolaspigenin and solaspigenin.

11. S. trilobatum Linn.

Eng: Climbing Brinjal; San: Alarka;

Mal: Tutavalam;

Tam: Tuduvalai;

Kan: Mullumusta;

Tel: Telavuste

It is mostly seen in South and Western India. The plant contains alkamine and solamarine. The berry and flowers are bechic and used in bronchitis. The alkaloid solamarine is antibiotic and possesses antitumour activity.

12. S. viarum Dunal, syn. S. Khasianum C. B. Clarke

Hin: Kantakari

It is widely distributed in Khasi, Jaintia and Naga hills of Assam and Manipur upto 2000m and in Sikkim, West Bengal, Orissa and in the Niligiris. The plant and berries contain solasonine (which on hydrolysis yields solasodine), solamargine, khasianine, nantigenin, solasodine, diosgenin and saponin-solakhasianin. The plant is spasmolytic and CNS active. The berry is a source of solasodine used in the synthesis of corticosteroidal hormones.

Agrotechnology: The agrotechnology for the solanaceous group of plants are almost similar. They come up very well in tropical and subtropical climate upto 2000m altitude. They can be raised on a variety of soils good in organic matter. Propagation is by seeds. The seedlings are first raised in the nursery and transplanted to the main field 30-45 days after sowing when the plants attain 8-10cm height. During rainy season, planting is done on ridges while during summer in furrows, at a spacing ranging from 30-90cm depending upon the stature and spreading habit of the plant. The transplanted seedlings should be given temporary shade for 2-4 days during summer. FYM or compost at 20-25t/ha is applied at the time of land preparation. A moderate fertiliser dose of 75:40:40 N, P2O5, K2O/ha may be given. P is given as basal dose, N and K are applied in 2-3 split doses. One or two intercultural operations are needed to control weeds. The plants need earthing up after weeding and topdressing. Irrigation is needed at 3-4 days interval during summer and on alternate days during fruiting period. Plants need staking to avoid lodging due to heavy bearing. Shoot borers, mealy bugs, leaf webbers and miners are noted on the crop, which can be controlled by spraying mild insecticides. Root knot nematode, wilting and mosaic diseases are also noted on the crop. Field sanitation, crop rotation and burning of crop residues are recommended.... solanums

C. B. Clarke.

Synonym: S. angustifolia Buch.- Ham ex. D. Don var. pulchella Burkill.

Family: Gentianaceae.

Habitat: Sub-tropical Himalaya from Himachal Pradesh to Bhutan, the Khasi and Lushai Hills, Manipur at 300-1,800 m. Bihar and Peninsular India up to 1,800 m.

Ayurvedic: Kiraatatikta (related species).

Action: Febrifuge and bitter tonic.... swertia affinis

King.

Synonym: Hydnocarpus Kurzii (King.)Warb. H. heterophyllus Kurx.

Habitat: Throughout upper Assam and Tripura in evergreen forests.

Folk: Chaalmogra.

Action: Kernel yields the true Chaal- moogra Oil (Oleum Chaulmoograe), used externally in leprosy.

Bark—astringent, rich in tannins, also used as a febrifuge.... taraktogenos kurzii

Aegle marmelos

Rutaceae

San: Bilva, Sriphal Hin, Ben, Ass: Bael Mal: Koovalam

Tam: Vilvam Mar,

Ben: Baela

Tel: Marendu, Bilvapondu

Guj: Bilviphal

Kan: Bilvapatra

Importance: Bael or Bengal quince is a deciduous sacred tree, associated with Gods having useful medicinal properties, especially as a cooling agent. This tree is popular in ‘Shiva’ and ‘Vishnu’ temples and it can be grown in every house. Its leaves are trifoliate symbolizing the ‘Thrimurthies’-Brahma, Vishnu, Shiva, with spear shaped leaflets resembling “Thrisoolam” the weapon of Lord Shiva. Many legends, stories and myths are associated with this tree. The leaflets are given to devotees as ‘prasadam’ in Shiva temples and as ‘Tulasi’ in Vishnu temples.

Every part of the tree is medicinal and useful. The roots are used in many Ayurvedic medicines for curing diabetes and leprosy. It is an ingredient of the ‘dasamoola’. The Bark is used to cure intestinal disorders. Leaves contain an alkaloid rutacin which is hypoglycaemic.

‘Two leaves before breakfast’ is said to keep diabetes under control. Leaves and fruits are useful in controlling diarrhoea and dysentery. Fruit pulp is used as ‘shampoo’ and cooling agent. It is also a rich source of carbohydrate, protein, fat, fibre, minerals and vitamin B and C. Fruit pulp is used to cure mouth ulcers as it is the richest natural source of riboflavin (1191 units/ 100 g). ‘Bael sharbat’ is prepared by mixing the fruit pulp with sugar, water and tamarind juice, which is very useful for stomach and intestinal disorders. The rind of the fruit is used for dyeing and tanning. The aromatic wood is used to make pestles in oil and sugar mills and also to make agricultural implements (Rajarajan, 1997).

Distribution: Bael tree is native to India and is found growing wild in Sub-Himalayan tracts from Jhelum eastwards to West Bengal, in central and south India. It is grown all over the country, especially in the premises of temples and houses.

Botany: Aegle marmelos (Linn.) Corr.ex Roxb. belongs to the citrus family Rutaceae. The golden coloured bael fruit resembles a golden apple and hence the generic name Aegle. The specific name marmelos is derived from marmelosin contained in the fruit (Nair, 1997). Aegle marmelos is a medium sized armed deciduous tree growing upto 8m in height with straight sharp axillary thorns and yellowish brown shallowly furrowed corky bark. Leaves are alternate, trifoliate and aromatic; leaflets ovate or ovate-lanceolate, crenate, pellucid- punctate, the laterals subsessile and the terminal long petioled. Flowers are greenish-white, sweet scented, borne on axillary panicles. Fruit is globose, woody berry with golden yellow rind when ripe. Seeds are numerous oblong, compressed and embedded in the orange brown sweet gummy pulp.

Agrotechnology: Bael comes up well in humid tropical and subtropical climate. It grows on a wide range of soils from sandy loam to clay loam. North Indian varieties are preferred to South Indian types for large scale cultivation. Twelve varieties are cultivated in North India for their fruits. Kacha, Ettawa, Seven Large, Mirsapuri and Deo Reo Large are varieties meant specially for ‘Sharbat’. The plant is propagated mainly by seeds and rarely by root cuttings. Seeds are freshly extracted from ripe fruits after removing the pulp and then dried in sun. Seeds are soaked in water for 6 hours and sown on seed beds which are covered with rotten straw and irrigated regularly. Seeds germinate within 15-20 days. One month old seedlings can be transplanted into polybags which can be planted in the field after 2 months. Budded or grafted plants as well as new saplings arising from injured roots can also be used for planting. Grafted plants start yielding from the 4th year while the trees raised from seeds bear fruits after 7-10 years. Planting is done in the main field with onset of monsoon in June-July at a spacing of 6-8m. Pits of size 50cm3 are dug. Pits are filled with a mixture of top soil and 10kg of well decomposed FYM and formed into a heap. Seedlings are transplanted in the middle of the heap and mulched. Chemical fertilisers are not usually applied. The dose of organic manure is increased every year till 50kg/tree of 5 years or more. Regular irrigation and weeding are required during early stages of growth. No serious pests and diseases are noted in the crop. Bael tree flowers during April. The flowers are aromatic with pleasant and heavenly odour. The fruits are set and slowly develop into mature fruits. Fruits are seen from October-March. A single tree bears 200-400 fruits each weighing 1-2 kg. Roots can be collected from mature trees of age 10 years or more. Tree is cut down about 1m from the ground. The underground roots are carefully dug out. Roots with the attached wood is then marketed (Rajarajan,1997).

Properties and activity: Bael is reported to contain a number of coumarins, alkaloids, sterols and essential oils. Roots and fruits contain coumarins such as scoparone, scopoletin, umbelliferone, marmesin and skimmin. Fruits, in addition, contain xanthotoxol, imperatorin and alloimperatorin and alkaloids like aegeline and marmeline identified as N-2-hydroxy-2- 4 - (3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide. - sitosterol and its glycoside are also present in the fruits. Roots and stem barks contain a coumarin - aegelinol. Roots also contain psoralen, xanthotoxin, 6,7-dimethoxy coumarin, tembamide, mermin and skimmianine. Leaves contain the alkaloids - O-(3,3-dimethyl allyl)-halfordinol, N-2-ethoxy-2 (4-methoxy phenyl) ethyl cinnamide, N-2-methoxy-2-(4-3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N- 2-4-(3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N-2-hydroxy-2- 4-(3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N-4-methoxy steryl cinnamide and N-2-hydroxy-2-(4- hydroxy phenyl) ethyl cinnamide. Mermesinin, rutin and -sitosterol - -D-glucoside are also present in the leaves (Husain et al, 1992).

Root, bark, leaves and fruits are hypoglycaemic, astringent and febrifuge. Root, stem and bark are antidiarrhoeal and antivenin. Leaf is antiinflammatory, expectorant, anticatarrhal, antiasthamatic, antiulcerous and ophthalmic. Flower is emetic. Unripe fruit is stomachic and demulcent. Ripe fruit is antigonorrhoeal, cardiotonic, restorative, laxative, antitubercular, antidysenteric and antiscorbutic. Seed is anthelmintic and antimicrobial (Warrier et al, 1993).... bael

Terminalia spp.

Combretaceae

The genus Terminalia includes a large group of medicinally valuable trees. They belong to the family Combretaceae.

The most important medicinal species of the genus Terminalia are the following.

1) T. arjuna (Roxb.ex DC) Wight & Arn.

San: Arjunah, Kakubhah;

Hin: Arjun, Kahu, Kahua;

Mal: Marutu, Nirmarutu, Venmarutu, Attumarutu, Pulamatti;

Tam: Attumarutu, Nirmarutu, Vellaimarutu, Marutu;

Kan: Maddi.

It is a large evergreen tree commonly found in Madhya Pradesh, Bihar and Peninsular and India. It has buttressed trunk and spreading crown with drooping branches. Bark is smooth, grey outside and flesh coloured inside, flaking off in large flat pieces. Leaves are simple, sub-opposite, oblong or elliptic, coriaceous, crenulate, pale dull green above, pale brown beneath, often unequal sided, nerves 10-15 pairs and reticulate. Flowers are white, arranged in panicles of spikes with linear bracteoles. Fruits are ovoid or oblong with 5-7 short, hard angles or wings, the lines on the wings oblique and curving upward (Warrier et al 1996).

The bark is useful in fractures, ulcers, urethrorrhoea, leucorrhoea, diabetes, vitiated conditions of pitta, anaemia, cardiopathy, fatigue, asthma, bronchitis, tumours, internal and external haemorrhages, cirrhosis of the lever and hypertension. It is used in fractures and the powdered bark is taken with milk. The bark powder is diuretic and has a general tonic effect in cases of cirrhosis of liver. The bark has been considered by the ayurvedic physicians as well as by modern practitioners as a cardiac tonic. It is given as a decoction with milk (NRF, 1998). In Ayurveda, “Arjunaghrita” and “Arjunarishta” are two important cardiotonic preparations of this drug.

Fruits contain flavanones - arjunone and 5,7,2’, 4’ - tetramethoxy flavone and a chalcone - cerasidin. Other constituents are -sitosterol, friedelin, methyloleanolate, gallic acid, ellagic acid and arjunic acid. Bark gave a triterpene arjungenin, triterpene glucosides I, II and III. Stem bark gave flavones - baicalein and arjunolone characterised as 6,4’ - dihydraxy - 7-methoxy flavone. Stem bark yields oxalic acid and tannins besides complex glycosides (Bhatra et al, 1980). Bark is alexertic, styptic, antidysenteric, astringent, antiasthmatic, febrifuge, expectorant, cardiotonic aphrodisiac and diuretic. Fruit is deobstruent. Stem-bark is CVS and CNS active, diuretic and abortifacient. Aerial part is CNS depressant and semen coagulant.

2) T. alata Heyne ex Roth. Syn. T. tomentosa (Roxb. Ex. Dc.) W & A.

San: Dharaphala, Saradru, Sajada;

Hin. Ain;

Ben: Asan, Paishal;

Mal: Tehmbara;

Tam: Karramarda, Karu Murutha, Marudam, Pudavam.

This tree is distributed in Himalaya from Kangra eastwords to Goalpara in Assam and southwards throughout the Peninsular India, upto 1200 m. The bark of the tree is widely used in ulcers, fractures, bronchitis and diarrhoea. Hydrolysis of the gum gives oligosaccharides, disaccharides and monosaccharides. Leaves and fruits give -sitosterol. Bark is diuretic, antihaemorrhagic, styptic, cardiotonic and semen coagulant.

3) T. bellirica (Craertn.) Roxb.

San: Aksha, Anilaghanaka, Baheduka, Harya, Kalinda;

Hin: Bulla, Sagona;

Ben: Bahera, Baheri;

Tam: Akkam, Kalanduri, Tani;

Tel: Bhutavasamu Tadi, Tandra, Vibhutakamu.

Belliric Myrobalan is distributed throughout India, upto 900 m. Its bark is used in anaemia and leucoderma. The fruit is used in bronchitis, strangury, sore throat, diseases of eye, nose, heart and bladder, hoarseness and piles. It forms an important constituent of the ayurvedic drug ‘triphala’. Furits contain -sitosterol, gallic and ellagic acids, ethyl gallate, galloyl glucose, chebulagic acid and a cardiac glucoside bellaricanin. Alcoholic extract of the fruit possesses bile-stimulating activity. Alcoholic extract, 30 mg/kg does not affect blood pressure and respiration, but a higher dose of 60 mg/kg produces a fall in blood pressure. Furit has anticancerous and flower has spermicidal activity. Bark is mild diuretic. Fruit is astringent, antidropsical, antileprotic, antiinflammatory, antidiarrhoeal, antibilious, stomachic, antiasthmatic, tonic, anticephalgic, bechic, anthelmintic and attenuant. Kernel is narcotic. Semi -ripe fruit is purgative. Gum is demulcent (Husain et al, 1992)

4) T. bialata steud.

White Chugalam or silver grey wood is a common tree of Andaman Islands. Its bark is used as a cardiac stimulant.

5) T. Catappa Linn.

San: Grahadruma;

Hin: Badam;

Ben: Bangla Badam:

Tam: Natuvdom, Vadhamkottai;

Tel: Vedam, Voda Movettilla; Mar: Jangli Badama, Nat Badam.

Indian Almond or Tropical Almond is a popular tree cultivated throughout the warmer parts of India including Andaman Islands and other adjacent island. Oil from the kernel is a substitute for almond oil. The leaf is used in scabies and colic. Husk and endocarp contain tannins and pentosans. Oil from kernel contains oleic, linoleic, palmitic and stearic acids. Heart wood and stem bark contains -sitosterol and its palmitate. Heartwood in addition contains terminolic acid and triterpenic methyl esters. The aerial part of the plant is diuretic. The bark is astringent, mild diuretic, cardiotonic and antidysenteric. Leaf is sudorific, antirheumatic, antileprotic and anticephalalgic.

6) T. Coriacea (Roxb.) syn. T. tomentosa (Roxb. ex. DC.) W. & A. var. coriacea (Roxb.) C. B. Clarke

Tam: Anaimikkuvam, Sadagam;

Kan: Banapu;

Tel: Tani.

Leathery Murdah is a tree commonly used as a cardiac stimulant. It is widely distributed in the drier and warmer parts of Andhra Pradesh and Tamil Nadu upto 1350 m and in Central India. Its bark is mainly used as a cardiac stimulant and in atonic diarrhoea and callous ulcer. It is also CVS active.

7) T. myriocarpa Heurck. & Muell. Arg.

Ben: Panisaj; Ass: Hollock, Jhalna.

Hollock is a tree of the Himalayas widely distributed from Nepal to Arunachal Pradesh and in Assam at 1000 m. The bark is cardiac stimulant and mild diuretic. Bark give -sitosterol, fructose and 4,4’,5,5’,6,6’ - hexadydroxy diphenic acid dilactone. Bark also contains tannis - ellagic, gallic, chebulinic and chebulagic acids.

8) T. Pallida Brandis.

Tam: Vellai Kadukkay;

Tel: Tella Karaka, Velama Karka.

The plant is distributed throughout south India, upto 600m. Its bark is a mild diuretic.

9) T. Paniculata Roth.

Mal: Marutu, Pe Marutu, Ven Marutu;

Tam: Pei Kadukai, Ven Maruthu, Ilai Kadukkay, Marudu, Pullatti;

Tel: Nimiri, Pulamaddi, Putamanu, Pulanallamanu;

Kan: Maruva, Matti.

Flowering Murdah is a tree which is widely used in opium poisoning. It is distributed in the Western and Eastern Ghats, upto 1200m. The bark is used in parotitis and flowers in opium poisioning. Heart wood give 3, 3’-0-di-methylellagic acid and 3,4,3’0-trimethyl flavellagic acid, -sitosterol, an uncharacterized triterpene carboxylic acid; a glycoside -3,3’ di-0 - methyl ellagic acid - 4 - monoglucoside and 0 - penta methyl flavellogic acid. The stem bark is anticancerous, diuretic, cardiotonic CVS active and shows antagonism of amphetamine hyperactivity. Flower is anticholerin (Husain et al, 1992)

10) Terminalia chebula Retz. Syn. Myrobalanus chebula (Retz.) Gaertner

Eng: Chebulic myrobalan;

San,

Ben: Haritaki;

Hindi:Harara, Harir,

Har; Mal:Kadukka; Ass:Hilikha; Kan:Alale;

Mar:Habra,

Hirada;

Ori:Harida;

Guj: Hirdo;

Pun:Helela;

Tam:Amagola;

Tel: Karaka

Chebulic myrobalan is a medium deciduous tree, the fruit of which is a common constituent of “Triphala” capable of imparting youthful vitality and receptivity of mind and sense. It is a major constituent in the ayurvedic preparations like Abhayarishta, Abhaya modak, Haritaki khand, Triphaladi churnam and Agastya rasayanam. In allopathy it is used in astringent ointments. In unani system, it is used as a blood purifier. The pulp of the fruit is given in piles, chronic diarrhoea, dysentery, costiveness, flatulence, asthma, urinary disorders, vomiting, hiccup, intestinal worms, ascites and enlarged spleen and liver. Powder of the fruit is used in chronic ulcers and wounds, carious teeth and bleeding ulceration of the gums. The bark is a good cardiac tonic. The fruit is valuable for its tannins and dyes. The wood is used for building purposes, agricultural implements, plywood and match box industries. It is also grown as a shade tree.

The plant is found throughout India chiefly in deciduous forests, on dry slopes upto 900m especially in Bengal, Tamil Nadu, West coast and Western Ghats. The plant is also reported in Sri Lanka, Nepal and Burma.

Terminalia chebula Retz. syn. Myrobalanus chebula (Retz.) Gaertner comes under family Combretaceae. It is a medium sized deciduous tree with a cylindrical bole, rounded crown, spreading branches with dark brown bark and brownish gray heartwood. Leaves are simple, alternate or subopposite, ovate or elliptic ovate with short petioles bearing 2 glands below the blades. Flowers pale yellow or white in 4-10cm long axillary spikes. Calyx tube hairy pale yellow and 5 lobed; no petals. Stamens consist of 10 filaments subulate, anthers small; ovary inferior, 1-celled with 2-3 pendulous ovule. Fruit is a drupe, ovoid glossy, glabrous, faintly angled and yellow to orange brown in colour. Seeds are hard and pale yellow.

Kernel oil of Chebulic myrobalan contains 6 fatty acids viz. Palmitic, stearic, oleic, linoleic, arachidic and behenic acid. The fruits contain chebulinic acid, tannic acid, gallic acid, chebulin and tannin. Leaves contain terpenes and saponins and -sitosterol is present in the bark (Beri, 1970; Khalique and Nizamuddin, 1972; Miglani and Chawla, 1974). Fruits are astringent, purgative, tonic, carminative, alternative and antispasmodic. Flowers and fruits are antiviral and hypoglycaemic. Wood is oxytocic and hypothermic (Husain et al, 1992).

Agrotechnology: Terminalia species are, in general, subtropical trees. Young plants prefer shade while the matured plants tolerate light frost and drought. It grows well in hilly areas. This is propagated by seeds. Natural multiplication happens rarely due to the poor seeds germination. Seeds soaked in water for 48 hours before sowing in seedbeds which should be covered with straw after sowing. It is watered immediately. Usually it takes 3-5 months to germinate. It can be transferred to polybags at two-leaf stage. One-year-old seedlings are ready for transplanting. For transplanting, pits are made of 50cm cube at a spacing of 4m. Organic manure, added regularly, promotes growth. Irrigation is required during first year. Weeds should be removed regularly. This plant grows slowly. It fruits within 6-7 years. This is continued for many years. It is coppiced well. Fruits are collected immediately after falling down or covered with soil to protect it from pests. Fruits dried well in sun and used or stored. The hard seed coat is removed before sowing.... terminalia

(Roxb.) Ridley.

Synonym: Anthistiria gigantea Hack. subspecies arundinacea Hack.

Family: Gramineae; Poaceae.

Habitat: The Himalayas and plains of India.

English: Ulla Grass. Karad grass is equated with T. quadrivalvis (L.) Kuntze.

Folk: Sarkharaa, Kapoor Ghass.

Action: Febrifuge.... themeda arundinacea

(Linn.) Gaertn.

Synonym: Eugenia acutangula L.

Family: Lecythidaceae; Barringtoni- aceae.

Habitat: Sub-Himalayan tracts from the Ganges eastwards to Assam and Madhya Pradesh.

English: Indian Oak. (Oak is equated with Quercus robur L.)

Ayurvedic: Nichula, Hijjala, Ijjala, Vidula, Ambuj. (Central Council for Research in Ayurveda & Siddha has wrongly equated Hijjala, Nichula and Vidula with Argyreia nervosa, Elephant Creeper.)

Unani: Samandarphal. (Saman- darphal is also equated with Rhus parviflora Roxb. in National Formulary of Unani Medicine.)

Siddha/Tamil: Kadappai, Samudra- phullarni.

Action: Leaf juice—given in diarrhoea. Fruit—bitter, acrid, anthelmintic, haemolytic, vulnerary; prescribed in gingivitis as an expectorant. Powdered seeds— emetic and expectorant. Bark— astringent, used in diarrhoea and blennorrhoea. Febrifuge. Wood— haemostatic (in metrorrhagia).

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the fruit in goitre; also in psychological disorders.

The bark contains tannins (16%), also ellagic acid.

The fruits contain triterpenoid sa- pogenins. Saponins possess haemolyt- ic properties.

A related sp. B. racemosa (L.) Roxb., found in Assam, eastern and western coasts of India and the Andaman Islands, is also equated with Samu- draphala and Hijjala.

European Oak (Quercus robur) contains 15-20% tannins, consisting of phlobatannin, ellagitannins and gallic acid. The bark is used as astringent, antiseptic and haemostatic.

Dosage: Fruit—1-3 g (API Vol. III.)... barringtonia acutangula

Linn.

Family: Berberidaceae.

Habitat: Distributed in Northwestern Himalayas.

English: Common Barberry, True Barberry.

Ayurvedic: Daruharidraa (var.).

Folk: Chatrod, Kashmal.

Action: Root and bark—used for ailments of gastrointestinal tract, liver, gallbladder, kidney and urinary tract, respiratory tract, also as a febrifuge and blood purifier.

Key application: Listed by German Commission E among unapproved herbs.

An extract with 80% berberine and additional alkaloids stimulated the bile secretion of rats by 72%. (PDR.) As cholagogue. (The British Herbal Pharmacopoeia.)

The main alkaloid is berberine (well tolerated up to 0.5 g). Berries are safe.

Bererine in small doses stimulates the respiratory system; poisonings have been observed from overdoses. Poisonings from the total herb have not been reported. (German Commission E.)

Berberine is bactericidal, amoebici- dal and trypanocidal. Berberine is an- tidiarrhoeal, asitentersinto the cytosol or binds to the cell membrane and inhibits the catalytic unit of andenylate cyclase. It is active in vitro and in animals against cholera.

Berberine stimulates bile secretion and shows sedative, hypotensive, anti- convulsant and uterine stimulant activity in animals. Alkaloid bermarine is also strongly antibacterial. It has been shown to increase white blood cell and platelet counts in animals with iatro- genic leukocytopaenia.

Berberine, berbamine and jatror- rhizine are hypotensive and sedative.

Many of the alkaloids are antineo- plastic.

The alkaloid berbamine (50 mg three times daily for 1-4 weeks) helped reverse leukopaenia induced by benzene, cancer chemotherapy or radiotherapy in a clinical study. (Francis Brinker.)

Berberine, when combined with pyrimethamine, was more effective than combinations with other antibiotics in treating chloroquine-resistant malaria. (Sharon M. Herr.)... berberis vulgaris

Linn.

Family: Bixaceae.

Habitat: Native to Central America, often cultivated in Madhya Pradesh and South India.

English: Annatto.

Ayurvedic: Sinduri, Sinduriyaa.

Siddha/Tamil: Jabara, Manjitti.

Action: Plant—astringent, antibil- ious, antiemetic, blood purifier. Leaves—infusion is given in jaundice, also in dysentery. Externally, scar-preventive. Root bark— febrifuge, antiperiodic. Seed pulp— haemostatic, antidysenteric, diuretic, laxative. Fruit—antidysenteric.

An antimicrobial constituent, mas- linic acid, alongwith gallic acid and pyrogallol, has been isolated from the leaves. Alcoholic extract of the leaves completely inhibited Micrococcus pyo- genes, but was inactive against E. coli. The aqueous extract, however, showed partial inhibition against E. coli. The aqueous extract also showed potent inhibitory activity towards lens aldose re- ductase, which plays an important role in the management of diabetic complications. The activity is attributed to a flavonoid, isoscutelarein.

Bixin, the main constituent of seed coat, shows cytostatic effect on the growth of human lymphoma cells. Bixin also has a hyperglycaemic effect and may disturb blood glucose control.... bixa orellana

Linn.

Family: Cucurbitaceae.

Habitat: Karnataka, Kerala and Tamil Nadu.

Ayurvedic: Patoli (related species of Patola).

Siddha/Tamil: Kombu Pudalai.

Action: Herb—bitter tonic, febrifuge. Root—purgative. Fruit— used as dentifrice.... trichosanthes nervifolia

Buch.-Ham ex Wight.

Family: Asclepiadaceae.

Habitat: Sub-Himalayas tract from Uttar Pradesh to Meghalaya and in central and Peninsular India.

Ayurvedic: Go-chandanaa.

Action: Toxic. Used as a substitute for Cephaelis ipecacuanha as emetic, purgative and febrifuge; externally on unhealthy ulcers and wounds.... tylophora fasciculata

(Roxb.) Kurz.

Synonym: B. glomerata DC.

Family: Compositae; Asteraceae.

Habitat: Tropical Himalayas, and throughout the plains of Assam and Penninsular India.

Ayurvedic: Kukundara (var.).

Unani: Kakarondaa.

Action: Plant—diuretic. Essential oil—CNS depressant.

The steam non-volatile fraction of plant extract contained a mixture of n-alkanes.

Blumea lacera.

Family: Compositae; Asteraceae.

Habitat: Throughout the plains of India, ascending to 700 m.

Ayurvedic: Kukundara, Kukuradru, Taamrachuuda.

Unani: Kakarondaa.

Siddha/Tamil: Narakkarandai, Kaatu Mullangi.

Folk: Kakranda.

Action: Plant—antipyretic. Leaf— astringent, febrifuge, diuretic, deobstruent, anthelmintic (particularly in case of thread worm). Root—anticholerin. Essential oil— antibacterial, antifungal.

The leaves on steam distillation yield 0.5% essential oil from which camphor is isolated.

The oil contains cineol 66, d-fen- chone 10 and citral about 6%. The plant gave a diester of coniferyl alcohol, acetylenic compounds, a thiophene derivative; aerial parts gave campes- terol, hentriacontane, hentriacontanol, alpha-amyrin and its acetate, lupeol and its acetate and beta-sitosterol.

The alcoholic extract of the plant showed marked anti-inflammatory activity in carrageenin and bradykinin- induced inflammation in rats.

Dosage: Root—5-10 g paste. (CCRAS.)... blumea fastulosa

Linn.

Family: Boraginaceae.

Habitat: The Mediteranean region, Europe and Asia.

English: Borage, Cow's Tongue Plant.

Unani: Gaozabaan (Onosma bracteatum Wall. has also been equated with Gaozabaan).

Action: Fresh herb (compounded with water)—refreshing, restorative and nervine tonic. Leaves and flowers—diuretic, febrifuge, expectorant, demulcent, emollient; promote the activity of kidneys; alleviate pulmonary affections.

The drug strengthens adrenal glands and is given for stress, mental exhau- sion and depression; provides support to stomach and intestines in cases of infection and toxicity. Used as a tonic to counteract the lingering effects of steroid therapy. Seeds relieve irritable bowel syndrome and regulate menstruation.

The leaves contain lycopsamine and supindine viridiflorate as the predominant unsaturated pyrrolizidine alkaloids. Due to low concentration of these alkaloids Borage is not toxic.

The drug contains potassium and calcium, combined with mineral acids. The fresh juice affords 30%, the dried herb 3% of nitrate of potash. The stems and leaves supply much saline mucilage. These saline qualities are mainly responsible for the wholesome invigorating properties of Borage.

Borage imparts pleasant flavour and cooling effect to beverages. In India, squashes and syrups, sold during summer, contain Borage extract.

Borage contains ascorbic acid (38 mg/100 g). Flowers contain cholin, glucose, fructose, amino acids, tannin (about 3%). Seeds contain protein (20.9%) and an oil (38.3%). The seed oil is one of the important sources of gamma-linoleic acid and linoleic acid. Borage oil, combined with Evening Primrose oil, is used in hypercholes- terolaemia.

Borage seed oil is used for rheumatoid arthritis, atopic eczema, infantile seborrhoeic dermatitis, neurodermati- tis, also for PMS and for preventing heart disease and stroke. Only UPA (unsaturated pyrrolizidine alkaloids) free oil is given internally.

Listed by German Commission E among unapproved herbs.

It has been suggested that borage not be used with drugs known to lower the seizure threshold such as tricyclic an- tidepressants and phenothiazines due to GLA content (only borage seed oil contains significant amounts of GLA). (Francis Brinker.)... borago officinalis

DC.

Synonym: V. arborea Hook. f. non- Buch.-Ham.

Family: Compositae; Asteraceae.

Habitat: West Bengal, Assam, Meghalaya and Western Ghats.

Siddha/Tamil: Shutthi.

Action: Bark—febrifuge. The bark is chewed as a substitute for betel leaves.... vernonia javanica

Linn. f.

Family: Verbenaceae.

Habitat: Throughout Deccan Peninsula.

Ayurvedic: Paaraavata-padi, Kaakajanghaa. (Kaakajanghaa is also equated with Leea aequata Linn.)

Action: Roots—febrifuge, astringent.

Ethanolic extract and cold aqueous infusion of the leaf were found to suppress acetic acid-induced writhing in mice and carrageenan-induced hind paw oedema in rats. The flavonoids exhibited anti-inflammatory activity.... vitex leucoxylon

Bacopa monnieri

Scrophulariaceae

San: Brahmi, Sarasvati;

Hin: Barami, Jalnim;

Ben: Boihim-sak;

Mal: Brahmi , Nirbrahmi;

Tam: Nirpirami, Piramiyapundu; Kan, Mar: Nirbrahmi

Importance: Brahmi or Thyme leaved gratiola is an important drug in Ayurveda for the improvement of intelligence and memory and revitalisation of sense organs. It clears voice and improves digestion. It is suggested against dermatosis, anaemia, diabetes, cough, dropsy, fever, arthritis, anorexia, dyspepsia, emaciation, and insanity. It dispels poisonous affections, splenic disorders and impurity of blood. It is useful in vitiated conditions of kapha and vata, biliousness, neuralgia, ascites, flatulence, leprosy, leucoderma, syphilis, sterility and general debility. The whole plant is used in a variety of preparations like Brahmighrtam, Sarasvataristam., Brahmitailam, Misrakasneham, etc. In unani Majun Brahmi is considered as a brain tonic.

Distribution: The plant grows wild on damp places and marshy lands in the major part of the plains of India, Pakistan, Afghanistan, Nepal, Sri Lanka and other tropical countries.

Botany: Bacopa monnieri (Linn.) Pennell. syn. Monniera cuneifolia Michx., Herpestis monniera (Linn.) H.B. & K. belongs to the family Scrophulariaceae. It is a prostrate, juicy, succulent, glabrous annual herb rooting at the nodes with numerous ascending branches. Leaves are simple, opposite, decussate, sessile, obovate-oblong or spatulate, entire, fleshy, obscurely veined and punctate. Flowers are pale blue or whitish, axillary, solitary, arranged on long slender pedicels. Fruits are ovoid, acute, 2-celled, 2-valved capsules and tipped with style base. Seeds are minute and numerous (Warrier et al, 1993).

Agrotechnology: The plant grows throughout the warm humid tropics upto 1200m elevation. Brahmi gets established well in water logged fields. The plant is propagated vegetatively by stem cuttings. Land is prepared by ploughing 2 or 3 times. Two to three tonnes/ha of cowdung or compost is applied and the field is again ploughed and levelled. Stem cuttings, 10cm long are spread at a spacing of 20cm. Waterlogging to height of 30cm is always required. Rooting may start within 15-20 days. It will spread over the field within 6 months. Regular application of organic manure will take care of the manurial requirement. Weeding once in a month is required. Care should be taken to maintain water level at a height of 30cm during the growth period. No serious pests or diseases are noted in this crop. Harvesting commences from sixth months onwards. Brahmi leaves can be collected once a month. After 3 years, the whole crop is harvested and removed. Fresh cultivation can be carried out in the same field.

Properties and activity: Earlier workers have reported the isolation of the alkaloids brahmine and hespestine and a mixture of 3 alkaloids from the leaves. Mannitol and saponins were reported later. Subsequent work described isolation of some C27, C29, and C31 hydrocarbons and betulic acid from this plant material. A systematic examination has resulted in the isolation and identification of two saponins designated as bacosides A and B. Bacoside A has chemical structure represented as 3-(-L-arabinopyranosyl)-O- - D-glucopyranoside-10, 20-dihydroxy-16-ketodammar-24-ene. The mixture of bacosides A and B on hydrolysis give four sapogenins, glucose and arabinose. The constitution of bacogenin A, has been established as 3 -30-dihydroxy-20(5)-25-epoxy-22-methyl-24-nor-dammar-22-en-16-one. Bacogenin A2 has been shown to be an isomer of bacogenin A, differing in configuration at C-20. Bacogenin A4 has been identified as ebelin lactone.

The plant is reported to have shown barbiturate hypnosis potentiation effect. The plant is anticancerous and improves learning ability. It is used as a tranquilliser. The plant is astringent, bitter, sweet, cooling, laxative, intellect promoting, anodyne, carminative, digestive, antiinflammatory, anticonvulsant, depurative, cardiotonic, bronchodialator, diuretic, emmenagogue, sudorfic, febrifuge and tonic (Basu et al, 1947; Rastogi et al 1960).... brahmi

Spreng.

Synonym: B. latifolia Roxb.

Family: Anacardiaceae.

Habitat: Drier parts of India.

English: Almondette tree, Cheron- jee, Buchanan's Mango.

Ayurvedic: Priyaala, Piyaala, Kharskandha, Bahulvalkala, Taa- paseshtha, Sannakadru Dhanush- pat, Chaar.

Unani/Tamil ? Saaraapparuppu.

Siddha: Mudaima, Morala (Tamil).

Action: Kernel—laxative, febrifuge. An ointment made out of the kernels is used to cure itch of the skin and to remove blemishes from the face. Oil from kernels— substitute for almond oil. Applied to glandular swellings of the neck. The oil is a promising source of palmitic and oleic acids.

Kernel lipids (65.6%), comprised mainly of neutral lipids (90.4%), consist mostly of triacylglycerol (82.2%), free fatty acids (7.8%) and small amount of diacylglycerols, monoacylglycerols and sterols.

The kernels are used in Indian medicine as a brain tonic. The leaves are valued as a cardiotonic.

The leaves contain 2.64% tannins (0.35% gallo-tannins). The presence of triterpenoids, saponins, flavonoids and reducing sugars are also reported. Powdered or crushed leaves are applied to wounds.

The bark contains 13.40% tannins. The presence of alkaloids, saponins and reducing sugars is also reported.

Gum (stem exudate) is antidiar- rhoeal. Used internally in rheumatism.

Dosage: Stem bark—5-10 g (API Vol. IV.)... buchanania lanzan

Australian quinine. Fever bark. Alstonia constricta, F. Muell. Bark.

Action: febrifuge, anti-periodic. Used by Australian aborigines for all kinds of fevers. Contains indole alkaloids.

Other uses: high blood pressure, mild analgesic, intermittent fevers.

Preparations: Thrice daily.

Tea: 1oz to 1 pint water simmered gently 5 minutes: one wineglassful. Liquid Extract: 5-30 drops. Powdered bark: 1-3g. Tincture. 15-60 drops. ... alstonia bark

Another term for FEBRIFUGE. ... anti-pyretic

Hydnocarpus kurzii (King). Brownish-yellow oil expressed from the seeds. Action: powerful alterative, mild sedative, mild febrifuge.

Uses: Has been used for a millennia exclusively for leprosy (Hansen’s disease). Of value in eczema, psoriasis and dermatitis.

Preparations: Orally, oil is taken in capsules or an emulsion: the initial doses 5-15 drops, increasing to 60 drops. Today, the oil is usually injected, weekly.

Externally, it is applied as an ointment: 10 per cent oil in 90 per cent soft paraffin. For scaly skin diseases, eczema, etc.

Specific for anal fissure. ... chaulmoogra

Baill.

Synonym: B. sempervirens Linn.

Family: Buxaceae.

Habitat: The Western and Central Himalayas and Punjab.

English: Himalayan Boxwood tree.

Folk: Chikri, Shamshaad. Paapari (Garhwal).

Action: Wood—diaphoretic. Bark— febrifuge. Leaves—purgative, diaphoretic; used in rheumatism. Poisonous. Not a safe drug for "purifying blood". Symptoms of poisoning are severe—abdominal pain, vomiting, convulsions and death.

The mixture of alkaloids is referred to as buxine. Buxenine-G is cytotoxic.

There is preliminary evidence that a specific Boxwood leaf extract (SVP 30) might delay disease progression in HIV-infected patients. The extract is available through internet sources or AIDS Buyers' Clubs. (Natural Medicines Comprehensive Database, 2007.)... buxus wallichiana

(L.) Roxb. Dandy & Exell.

Synonym: C. bonducella Flem. C. crista Linn.

Family: Caesalpiniaceae.

Habitat: Throughout the hotter parts of India. Common in West Bengal and South India. Often grown as hedge plant.

English: Fever Nut, Bonduc Nut, Nikkar Nut.

Ayurvedic: Puutikaranja, Lataa- karanja, Kantaki Karanja, Karanjin, Kuberaakshi (seed).

Unani: Karanjwaa.

Siddha/Tamil: Kazharchikkaai.

Action: Seed—antiperiodic, antirheumatic. Roasted and used as an antidiabetic preparation. Leaf, bark and seed—febrifuge. Leaf and bark—emmenagogue, anthelmintic. Root—diuretic, anticalculous.

The seeds contain an alkaloid cae- salpinine; bitter principles such as bon- ducin; saponins; fixed oil.

The seed powder, dissolved in water, showed hypoglycaemic activity in alloxanized hyperglycaemic rabbits. Aqueous extract of the seeds produced similar effects in rats. The powder forms a household remedy for treatment of diabetes in Nicobar Islands. In Kangra, Himachal Pradesh, roots are used in intermittent fevers and diabetes.

In homoeopathy, the plant is considered an excellent remedy for chronic fever.

(Three plant species—Pongamia pinnata Pierre, Holoptelea integrifo- lia (Roxb.) Planch. and Caesalpinia bonduc (L.) Roxb. are being used as varieties of Karanja (because flowers impart colour to water). P. pinnata is a tree and is equated with Karanja, Naktamaala and Udakirya; H. integri- folia, also a tree, with Chirabilva, Puti- ka (bad smell) and Prakiryaa; and C. bonduc, a shrub, with Kantaki Karanja or Lataa Karanja.)

Dosage: Seed kernel—1-3 g powder. (CCRAS.)... caesalpinia bonduc

(Jacq.) Willd.

Family: Caesalpiniaceae.

Habitat: Grows abundantly in South India, also cultivated in North-western India and West Bengal.

English: American Sumac, Divi-divi Plant.

Siddha/Tamil: Kodivelam.

Folk: Libi-dibi; Divi-divi.

Action: Bark—febrifuge, antiperi- odic. Pod—astringent (in piles). Fruit—semen coagulant.

All parts of the plant contain tannin, the maximum amount occurring in the pods (69.4%). The tannins from pods comprise pyrogallol type of hy- drolysable tannins and consists of gal- lotannin and ellagitannin. Divi-divi closely resembles myrobalans both in nature and contents of tannins. Seeds contain little or no tannin.

The plant is used for treating freckles. Leaves contain ellagic and gallic acids, catechol and tannins.

Ethanolic extract of the leaves showed antifungal activity.... caesalpinia coriaria

Jateorhiza calumba. N.O. Menispermaceae.

Synonym: Cocculus palmatus, Colombo.

Habitat: Ceylon.

Features ? Root bark thick, greyish-brown outside, transverse section yellowish, vascular bundles in radiating lines. Fracture short and mealy. Very bitter and mucilaginous in taste.

Part used ? Root.

Action: Tonic, febrifuge.

As a bitter tonic without astringency, in weakness of stomach function and indigestion generally. The infusion of 1 ounce of the powdered root to 1 pint of cold water is taken in two tablespoonful doses three or four times daily.

For bowel flatulence, U.S. Dispensatory gives ? 1/2 ounce each powdered Calumba and Ginger, 1 drachm Senna, infused in 1 pint boiling water. Dose, wineglassful three times daily.... calumba

Dragon’s claw. Corallorhiza odontorhiza, Nutt. Rhizome.

Keynote: fevers (early stages).

Action: febrifuge, diaphoretic, relaxant.

Uses: Once used widely in North American medicine for fevers, the rational being to induce a heavy sweat to reduce a high body temperature and relieve arterial excitement. Pleurisy. Typhoid fever. Preparations. Tea. Not given in this form, losing its strength on application of heat.

Tablets/capsules. 200mg. Two, every two hours, acute cases. Tincture. 30-60 drops. ... crawley root

No. 10. Equal parts: Lobelia herb, Pleurisy root, Crawley root, Catmint (Catnip), Sage. In powder form. Dose: One heaped teaspoon in cup; fill with boiling water; steep half an hour. 3-5 tablespoons every half hour while fever is on. Dose: small child, quarter of a teaspoon; child, half a teaspoon. For most kinds of fever it is a safe and efficient febrifuge. Never allow fever powder to be boiled. (Dr Melville Keith)

Widely used by the Eclectic School during second half of the 19th century. ... fever powder

Linn.

Synonym: C. horrida Linn.f.

Family: Cappariadaceae.

Habitat: Common in plains as a hedge plant.

English: Ceylon Caper.

Ayurvedic: Ahimsra (Himsraa and Ahimsra are synonyms). Vyaaghranakhi.

Siddha/Tamil: Aathondai.

Folk: Kareruaa.

Action: Root bark—sedative, stomachic, anticholerin, diuretic febrifuge. Leaves—applied as poultice to piles, swellings, boils.

The plant contains a saponin and p- hydroxybenzoic, syringic, vanillic, fer- ulic and p-coumaric acids. The leaves contain beta-carotene. The leaves and seeds contain glucocapparin, alpha- amyrin, n-triacontane and a fixed oil.

Aerial parts exhibited spasmolytic activity.... capparis zeylanica

Vahl.

Synonym: C. senna Linn. var. senna.

Family: Caesalpiniaceae.

Habitat: Native to Sudan and Arabia. Now cultivated mainly in Tirunelveli and Ramnathpuram districts and to a lesser extent in Madurai, Salem and Tiruchirapalli districts of Tamil Nadu. Also grown on a small scale in Cuddapah district of Andhra Pradesh and certain parts of Karnataka.

English: Indian Senna, Tinnevelly Senna.

Ayurvedic: Svarna-pattri, Maarkandikaa, Maarkandi.

Unani: Sannaa, Sanaa-makki, Senaai, Sonaamukhi, Sanaa-Hindi.

Siddha/Tamil: Nilaavaarai.

Folk: Sanaai.

Action: Purgative (free from astringent action of rhubark type herbs, but causes gripe), used in compounds for treating biliousness, distention of stomach, vomiting and hiccups. Also used as a febrifuge, in splenic enlargements, jaundice, amoebic dysentery. Contraindicated in inflammatory colon diseases.

Key application: Leaf and dried fruit—in occasional constipation. (German Commission E.) As a stimulant laxative. (The British Herbal Pharmacopoeia.) 1,8- dihydoxy-anthracene derivatives have a laxative effect. This effect is due to the sennosides, specifically, due to their active metabolite in the colon, rheinanthrone. The effect is primarily caused by the influence on the motility of the colon by inhibiting stationary and stimulating propulsive contractions. (German Commission E, ESCOP, WHO.) Seena has been included in I.P. as a purgative.

Most of the Senna sp. contain rhein, aloe-emodin, kaempferol, isormam- netin, both free and as glucosides, together with mycricyl alcohol. The purgative principles are largely attributed to anthraquinone derivatives and their glucosides.

Senna is an Arabian name. The drug was brought into use by Arabian physicians for removing capillary congestion (pods were preferred to leaves).

The active purgative principle of senna was discovered in 1866.

Cassia acutifolia Delile is also equated with Maarkandikaa, Svarna-pattri, Sanaai.

Dosage: Leaves—500 mg to 2 g (API Vol. I.)... cassia angustifolia

Mill.

Synonym: C. vulgaris Lam.

Family: Fagaceae.

Habitat: Darjeeling, Khasi Hills, Punjab and Himachal Pradesh.

English: Spanish Chestnut, Sweet Chestnut.

Folk: Singhaaraa (not to be confused with water-chestnut, Tripa natans L.)

Action: Leaves—astringent, antitussive and febrifuge (used for fevers and diseases of the respiratory tract). An infusion is used as a gargle in pharyngitis, proxysmal coughs, catarrh and whooping cough. Nuts—extract, as platelet inhibitor in thrombosis and atherosclerosis.

The leaves contain tannins (8-9%) flavone glycosides, triterpenoids, ursolic acid, lupeol and betulin. Heartwood contains 61.4% tannins and 25.7% nontannins. The wood and bark contain 714 and 8-14% tannins respectively.

Nuts are eaten raw, roasted or boiled like potatoes. Nuts contain protein,... castanea sativa

English Ivy. Hedera helix L. German: Efeu. French: Lierre. Spanish: Diedra o Yedra. Italian: Edera. Leaves, berries. Contains the saponins, hederine and emetine. Practitioner use.

Action: cathartic, diaphoretic, stimulant, antispasmodic, expectorant, febrifuge, anthelmintic, amoebicidal.

Uses: whooping cough, to liquefy bronchial phlegm. Berries macerated in vinegar to make an acid tincture used in the London plague. Hydrocephalus (single drop doses of fresh plant juice) traditional. Preparations. Locally, Ivy leaf poultice for swollen glands and chronic leg ulcer.

Ivy Leaf Corn Cure. ... ivy

combining form denoting an agent that drives away, repels, or eliminates. Example: febrifuge (a drug that reduces fever).... fuge

reduces fever; see also febrifuge.... antipyretic

(Roxb.) Loud.

Synonym: C. libani Barrel. var. deodara Hook. f.

Family: Pinaceae.

Habitat: North-western Himalayas from Kashmir to Garhwal, from 1,000 to 3,500 m.

English: Himalayan Cedar, Deodar.

Ayurvedic: Devadaaru, Suradru- ma, Suradaaru, Devakaashtha, Devadruma, Saptapatrika, Daaru, Bhadradaaru, Amarataru, Ama- radaaru, Daaruka, Devaahvaa, Surataru, Surabhuruha.

Unani: Deodaar.

Siddha/Tamil: Thevathaaram.

Action: Bark—decoction is used internally as astringent, antidiarrhoeal and febrifuge. Essential oil—antiseptic (used in skin diseases).

The Ayurvedic Pharmacopoeia of India indicated the use of the heart- wood in puerperal diseases.

The wood contains sesquiterpeno- ids; exhibits sapasmolytic activity. Alcoholic extract of the wood showed marked anti-inflammatory activity in mice; alcoholic extract showed antibacterial activity.

The wood possesses diaphoretic, diuretic and carminative properties, and is used in fevers and in pulmonary and urinary disorders.

Himalayan Cedarwood Oil contains two major sesquiterpenoids—alpha- and beta-himchalenes. Presence ofbu- tyric and caproic acids is also reported. The oil shows in vitro antibacterial and antifungal activity. It increases vascular permeability. Needles, on steam distillation, yield a volatile oil, rich in borneol and its esters. An alcoholic extract of the needles shows significant antibacterial activity against diptheria bacteria. The juice shows antiviral activity against tobacco mosaic virus and potato virus.

The bark contains 8-C methyltaxi- foline, dihydroquercetin, 8-C methyl- quercetin, quercetin, sitosterol, and tannins 8.25%, non-tannins 6.95% (varies with the age of the tree). An alcoholic extract of the bark shows significant activity against diptheria bacteria; aqueous extract of the dried bark showed anti-inflammatory activ ity against acute and chronic inflammations. Aqueous extract of the bark is found effective in reducing sugar content of diabetic patient's urine and blood to normal levels.

Dosage: Heartwood—3-6 g powder. (API Vol. IV.)... cedrus deodara

A. Juss.

Family: Meliaceae.

Habitat: Hills of Sikkim, Maharashtra, Tamil Nadu and the Andamans.

English: Bastard Cedar, White Cedar, Indian Red Wood.

Siddha/Tamil: Aglay, Melei Veppu.

Folk: Chikrassy.

Action: Bark—astringent, febrifuge, antidiarrhoeic, spasmolytic, diuretic. The plant is used in skeltal fractures.

The bark contains sitosterol, melia- none, scopoletin and 6,7-di-MeO- coumarin. The leaves gave querce- tin galactoside, galloyl glucocide and tannic acid. The bark and young leaves contain 15 and 20% tannin respectively. Seeds contain tetranortriterpenoids.

EtOH (50%) extract of the stem bark exhibited spasmolytic, hypoten- sive and diuretic activity. The saline extract of seeds showed haemaggluti- nating activity.... chukrassia tabularis

Linn.

Family: Compositae; Asteraceae.

Habitat: Native to the Mediterranean region, cultivated mainly in Northern India.

English: Succory, Endive.

Unani: Kaasani, Bustaani (Baaghi).

Action: Plant—antibilious. Root— demulcent, febrifuge, diuretic; used in dyspepsia; as a tonic for liver and digestive system. Milder than C. intybus.

Roots contain sesquiterpene lac- tones.

See C. intybus.... cichorium endivia

Linn.

Synonym: C. robusta How.

Family: Rubiaceae.

Habitat: Cultivated in West Bengal and Tamil Nadu.

English: Crown or Loxa Bark.

Ayurvedic: Quinine.

Unani: Al-keenaa, Kanakanaa.

Action: Antimalarial, febrifuge, astringent, orexigenic, sapasmolytic. Also prescribed in amoebic dysentery, jaundice, atonic dyspepsia, night cramps. Sometimes causes gastric and intestinal irritation.

Key application: In peptic discomforts such as bloating and fullness, loss of appetite. (German Commission E.)

The bark contains alkaloids quinine (2.35-4.42%); quinidine (1.44-2.56%); cinchonine (0.10-0.66%); cinchoni- dine (0.49-0.89%) and other alkaloids, quinamine, javanine (0.14-0.63%).

The leaves contain quercetin, kaem- pferol and avicularin.

Quinine is antimalarial; quinidine is antiarrhythmic and cardiac tonic, also used in psychic treatments.

The bark shows potent inhibitory activity against polymorphonuclear leucocytes; the activity is attributed to the alkaloids of the bark. Cinchona may potentiate coumarin derivatives. In large doses, it is sedative to CNS and cardiac plexus.

Quinine is toxic at over 3 g, quini- dine at 1 g.

Related Cinchona sp.: C. calisaya Wedd. (Nilgiris and Sikkim); C. calisaya Wedd. var. ledgeriana How. (West Bengal, Khasi Hills and Tamil Nadu); and C. succirubra Pav. ex Klotz. (Nilgiris and Annamalis in Tamil Nadu, Sikkim and West Bengal).

The bark of all the species contain quinine, quinidine, cinchonine and cinchonidine and exhibit antimalarial activity. The alcoholic extract of C. ledgeriana Moens ex Trimen bark exhibits antibacterial activity against Gram-positive bacteria comparable to sodium penicillin. The extract, however, exhibits lesser activity than di- hydrostreptomycin sulphate against Gram-negative bacteria.... cinchona officinalis

Centaury Tea has been known for centuries as a great medicinal remedy. It is said that Centaury plant is a very powerful diaphoretic, digestive, emetic, febrifuge, hepatic, homeopathic, poultice, stomachic, tonic and liver stimulator. Centaury is a plant from the gentian family which grows mainly in regions like Europe, Northern Africa and Eastern Australia. Also known as centaurium erythraea, this plant can easily be recognized by its triangular pale green leaves, pink flowers and yellowish anthers bloom. The fruit has the shape of a small oval capsule and it can only be harvested in the fall. Centaury Tea Properties Centaury has a bitter taste, which makes it a great ingredient for vermouth. Centaury Tea, however, is used by the alternative medicine for its great curative properties. The active constituents of Centaury Tea are: secoiridoids, alkaloids, phenolic acids, triterpenes, xanthone derivatives and triterpenes, which can only be released in the presence of hot water or other heating sources. Xanthone derivatives are also used by the alcohol producers in order to obtain a variety of liquors (especially the bitter ones). Centaury Tea Benefits Aside from its use as a vermouth ingredient, Centaury Tea has other health benefits, being prescribed by practitioners around the world since ancient times. Centaury Tea may be helpful in case you’re suffering from one of the following conditions: - Blood poisoning, by eliminating the toxins and increasing the blood flow. - A number of digestive ailments, such as constipation and gastritis. - Anemia, by nourishing the nervous system and increasing the coronary system function. - Diabetes and liver failure, by reconstructing the liver cells and lowering your blood sugar. - Kidney failure, by treating nephritis and other ailments of the urinary system. - Centaury Tea may also be used to induce appetite when taken before meals. How to make Centaury Tea Infusion Preparing Centaury Tea infusion is very easy. Use a teaspoon of freshly-picked or dried Centaury herbs for every cup of tea you want to make, add boiling water and wait 10 minutes for the health benefits to be released. Strain the decoction and drink it hot or cold. However, don’t drink more than 2 or 3 cups per day in order to avoid other health complications. Centaury Tea Side Effects When taken properly, Centaury Tea has no effects for adults. However, high dosages may lad to a number of ailments, such as nausea, diarrhea and vomiting. If you’ve been taking Centaury Tea for a while and you’re experiencing some unusual reactions, talk to your doctor as soon as possible! Centaury Tea Contraindications Don’t take Centaury Tea if you’re pregnant or breastfeeding. Also, children and patients suffering from severe diseases that require blood thinners and anti-coagulants ingestion should avoid taking Centaury Tea at all costs! The same advice if you’re preparing for a major surgery (Centaury Tea may interfere with the anesthetic). In order to gather more information, talk to an herbalist or to your doctor. Once he gives you the green light, add Centaury Tea to your shopping cart and enjoy the wonderful benefits of this tea responsibly!... centaury tea - diabetes treatment

Schrad.

Synonym: C. lanatus (Thunb.) Matsumura & Nakai.

Family: Cucurbitaceae.

Habitat: Cultivated throughout India on sandy river beds, up to an altitude of 1,500 m.

English: Watermelon.

Ayurvedic: Kalinga.

Unani: Tarbuz.

Siddha: Poiychaviral, Tharbuza- palam (Tamil.

Action: Pulp—cooling and refreshing, a rich source of pectin, carotenoids, surcose (as major sugar). Fruit juice is prescribed in strangury and urinary complaints, also in hepatic congestion and intestinal catarrh. Seeds—cooling, purgative, diuretic, demulcent (used in urinary infections). Leaves— febrifuge. The pericarp is given in diarrhoea.

Watermelon juice contains citrullin (0.17%) and arginine, which are thought to increase urea production in the liver, thus increasing the flow of urine.

The seeds possess a high lipase activity comparable to that of wheat germ, in addition to high lipoxygenase, urease and trypsin-inhibitor activities. Aqueous extract of the seeds also exhibit amylase inhibitor activity. The seed oil is used as a substitute for almond oil.

The roots of mature plant contain a triterpene, bryonolic acid. Bryono- lic acid possesses a stronger antiallergic activity with lesser side effects than that of glycyrrhetinic acid, the aglycone of glycyrrhizin, used clinically in Japan for the treatment of allergy and hepatitis.... citrullus vulgaris

Cinchona spp.

Rubiaceae

San: Cinchona, Kunayanah

Hin: Kunain Mal: Cinchona, Quoina

Tam: Cinchona

Importance: Cinchona, known as Quinine, Peruvian or Crown bark tree is famous for the antimalarial drug ‘quinine’ obtained from the bark of the plant. The term cinchona is believed to be derived from the countess of cinchon who was cured of malaria by treating with the bark of the plant in 1638. Cinchona bark has been valued as a febrifuge by the Indians of south and central America for a long time. Over 35 alkaloids have been isolated from the plant; the most important among them being quinine, quinidine, cinchonine and cinchonidine. These alkaloids exist mainly as salts of quinic, quinovic and cinchotannic acids. The cultivated bark contains 7-10% total alkaloids of which about 70% is quinine. Similarly 60% of the total alkaloids of root bark is quinine. Quinine is isolated from the total alkaloids of the bark as quinine sulphate. Commercial preparations contain cinchonidine and dihydroquinine. They are useful for the treatment of malarial fever, pneumonia, influenza, cold, whooping couphs, septicaemia, typhoid, amoebic dysentery, pin worms, lumbago, sciatica, intercostal neuralgia, bronchial neuritis and internal hemorrhoids. They are also used as anesthetic and contraceptive. Besides, they are used in insecticide compositions for the preservation of fur, feathers, wool, felts and textiles. Over doses of these alkaloids may lead to deafness, blindness, weakness, paralysis and finally collapse, either comatose or deleterious. Quinidine sulphate is cardiac depressant and is used for curing arterial fibrillation.

Distribution: Cinchona is native to tropical South America. It is grown in Bolivia, Peru, Costa Rica, Ecuador, Columbia, Indonesia, Tanzania, Kenya, Zaire and Sri Lanka. It was introduced in 1808 in Guatemala,1860 in India, 1918 in Uganda, 1927 in Philippines and in 1942 in Costa Rica. Roy Markham introduced the plant to India. The first plantation was raised in Nilgiris and later on in Darjeeling of West Bengal. The value of the tree was learnt by Jessuit priests who introduced the bark to Europe. It first appeared in London pharmacopoeia in 1677 (Husain, 1993).

Botany: The quinine plant belongs to the family Rubiaceae and genus Cinchona which comprises over 40 species. Among these a dozen are medicinally important. The commonly cultivated species are C. calisaya Wedd., C. ledgeriana Moens, C. officinalis Linn., C. succirubra Pav. ex Kl., C. lancifolia and C. pubescens. Cinchona species have the chromosome number 2n=68. C. officinalis Linn. is most common in India. It is an evergreen tree reaching a height of 10-15m. Leaves are opposite, elliptical, ovate- lanceolate, entire and glabrous. Flowers are reddish-brown in short cymbiform, compound cymes, terminal and axillary; calyx tubular, 5-toothed, obconical, subtomentose, sub-campanulate, acute, triangular, dentate, hairy; corolla tube 5 lobed, densely silky with white depressed hairs, slightly pentagonal; stamens 5; style round, stigma submersed. Fruit is capsule ovoid-oblong; seeds elliptic, winged margin octraceous, crinulate-dentate (Biswas and Chopra, 1982).

Agrotechnology: The plant widely grows in tropical regions having an average minimum temperature of 14 C. Mountain slopes in the humid tropical areas with well distributed annual rainfall of 1500-1950mm are ideal for its cultivation. Well drained virgin and fertile forest soils with pH 4.5-6.5 are best suited for its growth. It does not tolerate waterlogging. Cinchona is propagated through seeds and vegetative means. Most of the commercial plantations are raised by seeds. Vegetative techniques such as grafting, budding and softwood cuttings are employed in countries like India, Sri Lanka, Java and Guatemala. Cinchona succirubra is commonly used as root stock in the case of grafting and budding. Hormonal treatment induces better rooting. Seedlings are first raised in nursery under shade. Raised seedbeds of convenient size are prepared, well decomposed compost or manure is applied , seeds are broadcasted uniformly at 2g/m2, covered with a thin layer of sand and irrigated. Seeds germinate in 10-20 days. Seedlings are transplanted into polythene bags after 3 months. These can be transplanted into the field after 1 year at 1-2m spacing. Trees are thinned after third year for extracting bark , leaving 50% of the trees at the end of the fifth year. The crop is damaged by a number of fungal diseases like damping of caused by Rhizoctoria solani, tip blight by Phytophthora parasatica, collar rot by Sclerotiun rolfsii, root rot by Phytophthora cinnamomi, Armillaria mellea and Pythium vexans. Field sanitation, seed treatment with organo mercurial fungicide, burning of infected plant parts and spraying 1% Bordeaux mixture are recommended for the control of the diseases (Crandall, 1954). Harvesting can be done in one or two phases. In one case, the complete tree is uprooted, after 8-10 years when the alkaloid yield is maximum. In another case, the tree is cut about 30cm from the ground for bark after 6-7 years so that fresh sprouts come up from the stem to yield a second crop which is harvested with the under ground roots after 6-7 years. Both the stem and root are cut into convenient pieces, bark is separated, dried in shade, graded, packed and traded. Bark yield is 9000-16000kg/ha (Husain, 1993).

Properties and activity: Over 35 alkaloids have been isolated from Cinchona bark, the most important among them are quinine, quinidine, cinchonine, cinchonidine, cinchophyllamine and idocinchophyllamine. There is considerable variation in alkaloid content ranging from 4% to 20%. However, 6-8% yield is obtained from commercial plantations. The non alkaloidal constituents present in the bark are bitter glycosides, -quinovin, cinchofulvic, cinchotannic and quinic acids, a bitter essential oil possessing the odour of the bark and a red coloring matter. The seed contains 6.13% fixed oil. Quinine and its derivatives are bitter, astringent, acrid, thermogenic, febrifuge, oxytocic, anodyne, anti-bacterial, anthelmintic, digestive, depurative, constipating, anti pyretic, cardiotonic, antiinflammatory, expectorant and calcifacient (Warrier et al, 1994; Bhakuni and Jain, 1995).... cinchona

(Christm.) Swingle.

Synonym: C. medica L. var. acida (Roxb.) Hook. f.

Family: Rutaceae.

Habitat: Wild in the warm valleys of the outer Himalayas. Cultivated in the plains.

English: Acid or Sour Lime, Country Lime.

Ayurvedic: Nimbuka.

Unani: Limu Kaghzi.

Siddha/Tamil: Elummichhai, Thurinjippazham.

Folk: Kaagazi Nimbu.

Action: Antiscorbutic, stomachic, appetizer, refrigerant. Used in bilious vomiting. Leaves—an infusion is given for fever in jaundice, for sore throat, thrush. Root—an infusion is given for colic and dysentery, also as febrifuge.

Limes are rich in vitamins, minerals and alkaline salts, but not in fruit sugars. Lime peel contains ergosterol. An enzyme, 1,3-beta-glucan hydrolase has been reported from the bark and leaf extract. See C. limon.... citrus aurantifolia

(L.) Gaertn.

Family: Verbenaceae.

Habitat: Throughout India in tidal forests, wild all over coastal areas; planted in gardens in Tamil Nadu.

English: Smooth Volkameria.

Ayurvedic: Putigandhaa, Kundali, Vanajai.

Siddha/Tamil: Peenaari, Sangan- kuppi.

Folk: Lanjai.

Action: Leaf—febrifuge, alterative. Used as a substitute for Swertia chirayita and quinine in remittent and intermittent fevers. The leaf juice is taken orally to relieve muscular pains and stiffness of legs (in tetanus).

The leaves and stem contain a number of triterpenes, neolignans, diter- penoids, sterols and flavones.

The roots are prescribed in venereal diseases. The methanolic extract of the roots contains verbascoside which exhibits analgesic and antimicrobial properties.... clerodendrum inerme

(Linn.) Moon.

Family: Verbenaceae.

Habitat: A shrub distributed throughout the country, especially common in Assam and Bengal.

English: Blue-flowered Glory tree, Beetle Killer.

Ayurvedic: Bhaargi, Bhaaran- gi, Angaarvalli, Phanji, Braah- manyashtikaa, Kharshaak, Padma, Bhragubhavaa, Brahmayashtikaa.

Siddha/Tamil: Kandoorbarangi (root), cherutekku.

Action: Root—Antiasthmatic, antihistaminic, antispasmodic, antitussive carminative, febrifuge. Leaf—febrifuge.

The Ayurvedic Pharmacopoeia of India indicated the use of the dried roots in cough, bronchitis, dyspnoea, chest diseases and sinusitis.

The bark contains triterpenoids— serratagenic, oleanolic and queretaric acids; leaves contain alpha-spinasterol and flavonoids, including luteolin, api- genin, baicalein, scutellarein, phenolic acids—caffeic and ferulic acids.

EtOH (50%) extract of the plant exhibited hypotensive and spasmolytic activity. Polyhydric property on isolated guinea pig ileum. Antiasthmatic effect was also observed pharmacologically.

Dosage: Root—3-6 g powder; 1020 g for decoction. (API Vol. III.)... clerodendrum serratum

Choisy.

Synonym: C. Microphyllus Sieb. C. Prostratus Forsk

Family: Convolvulaceae.

Habitat: Throughout India, Ascending To 2,000 M In The Himalayas.

Ayurvedic: Shankhapushpi, Shankhaahvaa, Kshirapushpi, Maangalya Kusuma (White- Flowered). Blue-Flowered Var., Vishnukraanti, Vishnukraantaa, Vishnugandhi Is Equated With Evolvulus Alsinoides Linn.

Unani: Sankhaahuli (Blue-Flowered)

Siddha/Tamil: Sivakraandi (White- Flowered), Vishnukraandi (Blue- Flowered).

Action: Plant—Brain Tonic, Tranquilizer Used In Nervine Disorders, Mental Aberration, Anxiety Neurosis, Internal Haemorrhages, Spermatorrhoea. Also Astringent, Antidysenteric, Antispasmodic, Antiphlogistic, Febrifuge, Alterative. Flowers—Styptic, Used For Uterine Bleeding. Leaf—Antiasthmatic, Used In Chronic Bronchitis. Root— Used In Gastric And Duodenal Ulcers, Uterine Affections And For Promoting Fertility.

The Ayurvedic Pharmacopoeia Of India Recommends The Plant For Epilepsy. The Plant Contains Sankhpushpine Alkaloids.

The Alcoholic (50%) Extract Of The Plant, When Administered To Rats (Through Gastric Intubation At Different Intervals), Has Shown Enhanced Neuropeptide Synthesis Of The Brain. It Induces An Increase In Brain Protein Content And Increases Acquisition Efficiency.

Evolvulus Alsinoides Contains Pen- Tatriacontane, Triacontane And Beta- Sitosterol.

Shankhapushpi Syrup (A Compound Containing C. Pluricaulis, Centella Asiatica, Nardostachys Jatamansi, Nepeta Hindostana, Nepeta Elliptica And Onos- Ma Bracteatum), When Administered With Phenytoin, A Modern Antiepilep- Tic Drug, Reduced Not Only Antiepileptic Activity Of Phenytoin But Also Lowered Plasma Phenytoin Levels.

Dosage: Whole Plant—3-6 G Powder. (Api Vol. III.)... convolvulus pluricaulis

Indigofera tinctoria

Papilionaceae

San:Nilini, Ranjani, Nilika, Neelam, Aklika, Asita, Bhadra; Ben, Guj:Nil;

Hin:Gouli;

Mal: Neelamari;

Tam: Averi;

Tel: Aviri, Nili;

Kan: Nili; Mar: Nali; Ori: Neli

Importance: Common indigo or Indian indigo is a branching shrub which grows upto 2m high. Nili is a reputed drug produced from this plant which is used in ayurveda for the promotion of hair growth and it forms a major ingredient of preparations like nilibhringadi oil. This is the original source of natural indigo. Due to antitoxic property it is also a good remedy for poisons. According to Bhavaprakasa, nili is purgative in action, bitter, hot, cures giddiness, abdominal enlargement, vatarakta, gout and intestinal obstruction. The decoction or powder of the plant is used in whooping cough, bronchitis, palpitation of the heart, enlargement of the liver and spleen, dropsy, diseases of lungs and kidney, epilepsy and nervous disorders. A poultice of the leaves is recommended in skin diseases, piles, ulcer and haemorrhoids. A wine glass full juice of the leaves is administered in the morning with or without milk for three days to those who have been bitten by mad dogs. Root decoction is given in calculous diseases and used as an antidote to arsenic poisoning. The seed of the plant is powered and steeped in arrack or rum, yield a tincture, which is used to distroy lice. Indigo, the dye extracted from the leaves, is a soothing balm for burns and scalds, insect stings and animal bites. The synonyms visaghni and sodhani indicate the antitoxic and laxative properties of the drug nili, respectively (Aiyer and Kolammal, 1960).

Distribution: This plant is distributed in South and South East Asia, tropical Africa and is introduced in tropical America. In India, it is found almost throughout and cultivated in many parts.

Botany: Indigofera tinctoria Linn. syn. I. summatrana Gaertn, Pigmentum indicum belongs to Papilionaceae family. This is a branching shrub which grows upto 2m high. Stems and branches are green; branchlets silvery pubescent. Leaves are alternate, stipulate, imparipinnate and got 7-13 leaflets which are elliptic-oblong, membraneous,1.7x0.9cm, shortly mucronate, pale green or bluish. Flowers are small, rose-coloured in axillary racemes. Calyx 5-cleft, gamosepalous; corolla papilionaceous; stamens diadelphous; ovary sessile with a short incurved style ending in a capitate stigma. Pods are linear, cylindrical, 2-5cm long, deflexed having 8-12 seeds.

Agrotechnology: The Indian indigo requires good sunlight and grows well in hilly areas. This is usually propagated by seeds. Seeds are very small and the seed rate is 3kg/ha. Seeds require pretreatment for good germination as the seed coat is hard. Seeds are mixed with sand and ground gently to break the seed coat. An alternate method for enhancing germination is dipping the seeds in boiling water for a second. After pretreatment seeds are broadcasted. Broadcast the seeds preferably mixed with sand 2 or 3 times its volume to ensure uniform coverage. The seedbeds should be covered with straw and irrigated. Seeds germinate within 15 days. Seedlings are ready for transplanting after one month. For the land preparation, the soil is brought to fine tilth by ploughing 2 or 3 time s. Cattle manure should be applied at the rate of 10t/ha as basal dressing and incorporated into soil along with last ploughing. The best time for sowing is September-October. Weeding has to be done two times; 3 weeks after sowing and 6 weeks after sowing. Plants start flowering 2-3 months after sowing. Harvesting is done by cutting the plants at this time, at a height of about 10cm from ground level. Irrigate plants after harvest. Subsequent harvests can be made at 1.5-2 months interval. Four to five cuttings can be taken in an year depending on the growth. A few plants per plot are left without cutting to set seeds. Ripe pods are to be harvested in the early morning to prevent loss of seeds by shattering during harvest.

Properties and activity: A blue dyestuff is obtained from the indigofera which does not exist ready formed, but is produced during fermentation from another agent existing in the plant, known as indocan. Indocan is yellow amorphous of a nauseous bitter taste with an acid reaction, readily soluble in water, alcohol and ether. An artificial product indigotine is manufactured chemically and used as a substitute. Indirubin is another component of the plant.

The plant is deobstruent, alterative, antitoxic, antiasthmatic and antiepileptic. Aerial part is hypoglycaemic, CNS depressant and antitoxic. The leaves, flowers and tender shoots are considered to be cooling, demulcent and alterative. Leaf is antiinflammatory. Root and stem is laxative, expectorant, antitumourous, febrifuge, anticephalalgic, antidote for snake bite, anthelmintic and promotes growth of hair. Root is divertic. Indirubin is antineoplastic and has toxicity. Nili is antitoxic, purgative and laxative. Indigo is said to produce nausea and vomiting.... common indigo

Gmelina arborea

Verbenaceae

San: Gumbhari;

Hin:Gamari, Jugani-chukar;

Mal: Kumizhu, Kumpil;

Guj: Shewan; Pun:Gumbar; Mar: Shivanasal;

Kan: Kummuda;

Tam: Uni, Gumadi;

Tel: Gummadi;

Importance: Coomb teak, Candahar tree or Kashmeeri tree is a moderate sized, unarmed, deciduous tree which is a vital ingredient of the ”dasamula” (group of ten roots). The whole plant is medicinally very important. It promotes digestive power, improves memory, overcomes giddiness and is also used as an antidote for snake bite and scorpion sting. Roots are useful in hallucination, fever, dyspepsia, hyperdipsia, haemorrhoids, stomachalgia, heart diseases, nervous disorders, piles and burning sensation. Bark is used in fever and dyspepsia. Leaf paste is good for cephalagia and leaf juice is a good wash for foul ulcers and is also used in the treatment of gonorrhoea and cough. Flowers are recommended for leprosy, skin and blood diseases. The fruits are used for promoting the growth of hair and in anaemia, leprosy, ulcers, constipation, strangury, leucorrhoea, colpitis and lung disease.

Wood is one of the best and most reliable timber of India. It is used for making furniture, planks, carriages, printing boxes, musical instruments, shafts, axles, picture frames, jute bobbins, calipers, ship buildings, artificial limbs and stethoscopes.

In south India the bark of the tree is used by arrack manufacturers to regulate the fermentation of toddy. The plant is also grown in garden or avenues (Dey, 1988; Sivarajan and Indira, 1994).

Distribution: The plant is found wild throughout India from the foot of Himalayas to Kerala and Anadamans, in moist, semideciduous and open forests upto an altitude of 1500 m. It is also distributed in Sri Lanka and Philippines.

Botany: Gmelina arborea Roxb. Syn. Premna arborea Roth. belongs to Family Verbenaceae. It is an unarmed deciduous tree growing up to 20m height with whitish grey corky lenticellate bark, exfloliating in thin flakes. Branchlets and young parts are clothed with fine white mealy pubescence. Leaves are simple, opposite, broadly ovate, cordate, glandular, glabrous above when mature and fulvous-tomentose beneath. Flowers brownish yellow in terminal panicle. Calyx campanulate, pubescent outside and with 5 lobes. Corolla showy brownish yellow with short tube and oblique limbs. Stamens 4, didynamous and included. Ovary is 4 chambered with one ovule each; style slender ending in a bifid stigma. Fruits are fleshy ovoid drupes, orange yellow when ripe. Seeds 1 or 2, hard and oblong.

Agrotechnology: Coomb teak is a sun loving plant. It does not tolerate drought. But it grows in light frost. Rainfall higher than 2000mm and loose soil are ideal. The best method of propagation is by seeds but rarely propagated vegitatevely by stem cuttings also. Seed formation occurs in May-June. Seeds are dried well before use. They are soaked in water for 12 hours before sowing. Seed rate is 3kg/ha. Seeds are sown in nursery beds shortly before rains. Seeds germinate within one month. Seedlings are transplanted in the first rainy season when they are 7-10cm tall. Pits of size 50cm cube are made at a spacing of 3-4m and filled with sand, dried cowdung and surface soil, over which the seedlings are transplanted. 20kg organic manure is given once a year. Irrigation and weeding should be done on a regular basis. The common disease reported is sooty mould caused by Corticium salmonicolor which can be controlled by applying a suitable fungicide. The tree grows fast and may be ready for harvesting after 4 or 5 years. This plant is coppiced and traded. The roots are also used for medicinal purposes. The tree may stand up to 25 years.

Properties and activity: Roots and heart wood of Coomb teak are reported to contain gmelinol, hentriacontanol, n-octacosanol and -sitosterol. The roots contain sesquiterpenoid and apiosylskimmin, a coumarin characterised as umbelliferone-7-apiosyl glucoside and gmelofuran. The heart wood gives ceryl alcohol, cluytyl ferulate, lignans, arboreol, gmelonone, 6”-bromo isoarboreol, lignan hemiacetal and gummidiol. Leaves yield luteolin, apigenin, quercetin, hentriacontanol, -sitosterol, quercetogenin and other flavons. Fruits contain butyric acid, tartaric acid, and saccharine substances (Asolkar et al, 1992; Dey, 1988).

The roots are acrid, bitter, tonic, stomachic, laxative, galactogogue, demulcent, antibilious, febrifuge and anthelmintic. Bark is bitter, hypoglycaemic, antiviral, anticephalalgic and tonic. The leaves are demulcent, antigonorrhoeic and bechic. Flowers are sweet, refrigerant, astringent and acrid. Fruits are acrid, refrigerant, diuretic, astringent, aphrodisiac, trichogenous, alterant and tonic (Warrier et al; 1995).... coomb teak

Murraya Koenigii

Rutaceae

San: Kalasakh, Kaidaryah

Hin: Mithinim, Katnim

Ben: Barsunga

Mal: Kariveppu, Karuveppu

Tam: Kariveppilai, Karuveppu

Kan: Kari Baeva

Tel: Karivepaku

Ass: Narasingha, Bishahari

Importance: Curry leaf, a plant of homestead gardens has gained importance as a commercial crop and is cultivated for its culinary and medicinal value. The plant is highly esteemed for its leaves which promote appetite and digestion and destroy pathogenic organisms. It is reported to be useful in emaciation, skin diseases, hemopathy, worm troubles, neurosis and poisons. They are useful in vitiated conditions of kapha and pitta, hyperdipna, colic, flatulence, diarrhoea, dysentery, vomiting, inflammations and foul ulcers. “Kaidaryah” drug is prepared using this plant which improves voice, stimulates digestion and destroys concocted poisons in the system. The important preparations using the drug are Kalasadi kasayam, Pamantaka tailam, Jatyadi tailam, Jatyadi ghrtam, etc (Sivarajan et al,1994).

Distribution: Curry leaf is seen in the foot of the Himalaya and Bashahi eastwards to Sikkim and Peninsular India, upto 1700m. It is also found in Sri Lanka, Burma, Indo-China, South China and Hainan. Commercial cultivation in India is limited to Tamil Nadu and Karnataka states.

Botany: The genus Murraya of the family Rutaceae includes the following species:

M. Koenigii (Linn.) Spreng. syn. Bergera koenigii Linn.

M. Exotica Linn. syn. M. paniculata (Linn.) Jack.

Murraya koenigii is a small aromatic tree with dark grey bark and closely crowded spreading dark green foliage. Leaves are imparipinnate and alternate. Leaflets are alternate, obliquely ovate or somewhat rhomboid, gland dotted and strongly aromatic. Flowers are white, arranged in much branched terminal corymbose cymes and fragrant. Fruits are subglobose or ellipsoid berries, purplish black when ripe and 2-seeded (Warrier et al, 1995).

Agrotechnology: Curry leaf tree does not choose a specific climate and can come up even in dry climate too. In places where minimum temperature goes below 13 C, the growth of the shoot will be slightly affected. It comes up well in light textured red soils. DWD-1 and DWD-2 are two improved varieties released from UAS, Dharwad. Curry leaf is propagated by seed. Main field is to be ploughed repeatedly. A spacing of 90-120cm is followed on either side. Pits of size 30cm3 are dug out one month before planting and filled with top soil mixed with well decomposed FYM at the time of planting. Healthy seedlings are planted in the centre of the pits. Then long furrows are formed connecting all the pits to facilitate easy irrigation. The seedlings are irrigated once in 5-7 days upto 3 years and once in 15 days afterwards. The field should be kept free from weeds. Plants may be trained and pruned to maintain a bush of 1m in height. For better growth and yield, each plant is fertilised with 20kg of FYM besides 150:25:50g of N, P2O5, K2O/ year. Attack of aphids in the vegetative stage can be controlled by spraying of dimethoate at 2ml/l of water. Leaves from such sprayed plants should be harvested only after 10 days. Spraying carbendazim at 1g/l can take care of leaf spot diseases. The crop comes to first harvest at the end of first year. The yield of leaves account to 400kg/ha at the end of first year, 2000 to 2200kg/ha in the second and third year harvested at an interval of four months and 2500kg/ha in the fourth year harvested at three months interval. From fifth year onwards it is harvested at 2.5-3 months interval giving an yield of 3500-5000kg/ha (Kumar et al, 1997).

Properties and activity: All parts of the plant, especially the leaves are rich in carbazole alkaloids. These include members with (i) C13 - skeleton -murrayanin, mukoeic acid, mukonine and mukonidine; (ii) C18 - skeleton including gerinimbine, koenimbine, murrayacine, koenigine and koenigicine (koenidine); and (iii) C23- skeleton containing mahanimbine, mahanimbicine, iso- mahanimbicine, mahanine, mahanimbinine, murrayayazoline, murrayazolinine, murrayazolidine, cyclomahanimbine and bicyclomahanimbicine. Other carbazole bases include mukoline, mukolidine (C13 group, from roots), mukonicine (C18 from leaves), the biogenetically significant mukonal (C13, stem-bark), mahanimboline (C23, root-bark), iso- murrayazoline (C23, stem-bark). The leaves gave a coumarin glucoside, scopolin also. Essential oil from leaves contained -caryophylline, -gurjunene, -elemene, - phellandrene, -thujene as major constituents.

The roots, bark and leaves are bitter, acrid, astringent, cooling, aromatic, demulcent, depurative, anthelmintic, febrifuge, stomachic, appetising, carminative, antiinflammatory and antiseptic. Aerial part is spasmolytic and antiprotozoal. Root is antiprotozoal, CVS active and has effect on nictitating membrane. Leaf is hypoglycaemic (Hussain et al,1992).... curry leaf

(DC.) Stapf.

Synonym: Andropogon citratus DC.

Family: Poaceae.

Habitat: Grown in Punjab, Maharashtra, Gujarat and Karnataka.

English: Lemongrass.

Ayurvedic: Bhuutika, Bhuutikaa.

Action: Leaf—stimulant, sudorific, antiperiodic, anticatarrhal. Essential oil—carminative, anticholerin, depressant, analgesic, antipyretic, antibacterial, antifungal.

The lemongrass contains a volatile oil, with citral (about 70%), citronellal, geraniol and myrcene as its main constituents. Cetral and citronellal exhibit marked sedative activity.

The lemongrass is taken as a tea for digestive problems; it relaxes muscles of the stomach and gut, relieves spasm and flatulence. In catarrhal conditions, it is taken as a febrifuge.

An infusion of fresh leaves on oral administration has been found to produce dose-dependent analgesia in rats. This analgesic acitivity is caused by myrcene present in the leaf.

Geraniol and d-limonene from the essential oil induce activity of glu- tathione S-transferase, a detoxifying enzyme, which is believed to be a major factor for chemical carcinogen detoxification.... cymbopogon citratus

(Jones) Schult.

Synonym: Andropogon jwarancusa Jones.

Family: Poaceae.

Habitat: Himalayas from Kashmir to Assam, ascending up to more than 300 m and in the north-western plains.

Ayurvedic: Bhuutikaa, Laamajja- ka, Laamajja. (Subs. Vetiveria zizanioides (L.) Nash.)

Unani: Izkhar.

Action: Blood purifier, bechic, anticholerin, emmenagogue, febrifuge, antirheumatic (also used in gout). Flower—styptic. Essential oil—antimicrobial.

Major constituent of the essential oil is piperitone (64.7%) others include borneol, cadinene, camphene, camphor, farnesene, geraniol, alpha-and beta-pinene. The antibacterial activity is attributed to piperitone.... cymbopogon jwarancusa

Linn.

Synonym: D. fastuosa Linn.

Family: Solanaceae.

Habitat: Throughout India, particularly in waste place.

English: Thornapple, Downy Datura.

Ayurvedic: Dhattuura, Dhuurta, Dhastura, Unmatta, Shivapriya, Harapriya, Hema, Haatta, Dhustuu- ra, Dhustuuraka, Kanaka, Maatula. Also equated with Raaj-dhatuura. (white var.)

Unani: Dhaturaa.

Siddha/Tamil: Oomatthai, Karu- voomatthai.

Action: Various plant parts are used in headache, hemiplegia, epilepsy, delirium, convulsions, cramps, rigid thigh muscles, rheumatism. Leaf— antitumour, antirheumatic. Leaf and corolla—anti-inflammatory. Flower—antiasthmatic. Seed, leaf and root—anticatarrhal, febrifuge, antidiarrhoeal, antidermatosis; also used in cerebral complications. Seeds—used in asthma. Limited use in kinetosis (excessive salivation, nausea and vomiting).

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia ofIndia indicated the use of the whole plant in dysuria and alopecia.

The plant accumulates more hyos- cine than hyoscyamine. Hyoscine content of dried leaves and flowering tops—between 0.02-0.55%. Alkaloid content of leaves—0.55%; stem—0.4%; seeds—0.19%; pericarps—0.8%; root at flowering of the plant—0.77%.

Hyoscine in large doses causes delirium and coma.

Dosage: Seed—30-60 mg. (API Vol. III.)... datura metel

Rafin.

Synonym: Poinciana regai Bojer ex Hook.

Family: Caesalpiniaceae.

Habitat: Native to Madagascar; grown in gardens and avenues for ornamental purposes and for shade.

English: Flamboyant Flame tree, Gold Mohur.

Ayurvedic: Gulmohar (var.) White Gold Mohur is equated with Delonix elata Gamble, synonym Poinciana elata Linn.

Siddha: Vadanarayana, Pe- rungondrai, Mayarum. White Gulmohar. (Tamil)

Action: Bark—antiperiodic, febrifuge. Plant—antirheumatic, spasmogenic. Flowers (aqueous and alcoholic extract)—active against roundworm.

White Gulmohar trunk-bark yielded asparagine and aspartic acid. Flowers gave iso-quercetin.

Delonix regia bark gave leucocyani- din; bark and leaves contain tannin, lu- peol and beta-sitosterol, and free OH- proline as major amino acid. Flower anthers are a rich source of zeaxanthin.... delonix regia

(Linn.) Webb ex Prantl.

Synonym: Sisymbrium sophia L.

Family: Brassicaceae.

Habitat: Temperate Himalaya from Kashmir to Kumaon at 2,200-4,100, also in eastern Himalaya.

English: Flix Weed, Flax Weed.

Action: Leaf and flower—astringent, antiscorbutic. Seed—expectorant, anti-inflammatory, febrifuge, antidysenteric. Aerial parts— antiviral, hypoglycaemic.

The plants has been used externally for ulcers, seeds are used as substitute or adulterant of the seeds of Sisymbrium iro Linn. (The source of Khaakasi, Khubb, Tukhm-e-Shahuh, Khuubkalaan of Unani medicine, known as Hedge Mustard or London Rocket.)... descurainia sophia

Desmodium gangeticum

Fabaceae

San: Anshumati, Salaparni;

Hin,

Ben: Salpani;

Mal: Orila;

Tam:Pulladi;

Tel: Gitanaram

Kan: Murelehonne; Mar: Darh;

Guj: Salwan; Ori: Salaparni Pun: Shalpurhi

Importance: Desmodium is a small shrub which is the chief of the ten ingredients in the Dasamula kwatha of Hindu medicine. Roots are useful in vitiated conditions of vata, anorexia, dyspepsia, haemorrhoids, dysentery, strangury, fever, gout, inflammations, cough, asthma, bronchitis, cardiopathy and debility. The unani preparation “Arq dashmul” contains these roots. It is considered a curative for leucorrhoea and for pains due to cold (Warrier et al, 1995).

Distribution: The plant is widely distributed in the tropics and subtropics. It grows wild in the forests of India up to 1500m. It is also cultivated in the plains and in the lower Himalayas.

Botany: Desmodium gangeticum (Linn.) DC. syn. Hedysarum gangeticum Linn., Desmodium gangeticum var. maculatum (Linn.) Baker., belongs to the family Fabaceae (Papilionaceae). It is an erect diffusely branched undershrub, 90-120cm in height with a short woody stem and numerous prostrate branches provided with soft grey hairs. Leaves are unifoliate, ovate- lanceolate, membranceous and mottled with grey patches. Flowers are white, purple or lilac in elongate lax, terminal or axillary racemes. Fruits are moniliform, 6-8 jointed, glabrescent pods, joints of pods separately pubescent with hooked hairs, joint separating when ripe into indehiscent one seeded segments. Seeds are compressed and reniform.

Agrotechnology: Desmodium can grow in a variety of climate and soils. However, it prefers tropical and subtropical climatic conditions. Although it can grow on all types of soils, waterlogged and highly alkaline soils are not suitable. Light sandy loam is preferred for commercial cultivation.

It is propagated through seeds. Seeds can be planted directly in the field or seedlings raised on the nursery beds and transplanted. Transplanting always gives better results in commercial cultivation, as it gives assured crop stand. Planting is done at a spacing of 40x20cm on flat beds or ridges. Organic manures are applied at the time of land preparation and thoroughly mixed with the soil. A little quantity of phosphatic and nitrogenous fertilizers are also applied for better crop growth. The inter-row spaces between plants, both in the field and nursery should be kept free from weeds by frequent weeding and hoeing as the plant suffers from weed competition, especially during early stages of growth. Manual hand weeding is usually done. Irrigation of seedlings just after planting is good for crop establishment. Although it can be cultivated as a rainfed crop under humid tropical conditions, irrigation every month is beneficial during summer. The root is the economic part and harvesting can be commenced after 8-9 months. About 500- 700kg roots can be harvested from a hectare of land per year.

Properties and activity: The root contains gangetin, gangetinin, desmodin, N,N-dimethyl tryptamine, hypaphorine, hordenine, candicine, N-methyl tyramine and -phenyl ethyl amine. The total alkaloid fraction showed hypotensive activity. The root is bitter, antiinflammatory, analgesic, aphrodisiac, constipating, diuretic, cardiotonic, expectorant, astringent, antidiarrhoeal, carminative, antiemetic, febrifuge and anti-catarrhal (Thakur et al, 1989).... desmodium