Fetal Growth Chart: From 1 Different Sources
a graph, customized to a pregnant woman’s height, weight, and other factors, that plots *fundal height and estimated fetal weight on ultrasound against weeks of gestation. The graph, which shows centile lines (see centile chart), improves prediction of a baby who is *small for gestational age.
The most commonly used chart for testing the acuity of distant VISION. The chart comprises rows of capital letters, with the letters in each row being smaller than those in the one above. The top line of large letters can be seen by a normally sighted person standing 60 metres away. The subject under test sits 6 metres from the screen and, if he or she can read the 6-metre line of letters, his or her visual acuity is normal at 6/6.... snellen chart
A procedure performed during a mother’s labour in which a blood sample is taken from a vein in the scalp of the FETUS. This enables tests to be performed that indicate whether the fetus is, for example, suffering from a shortage of oxygen (HYPOXIA). If so, the obstetrician will usually accelerate the baby’s birth.... fetal blood sampling
A procedure in which cells – for example, from the pancreas – are taken from an aborted FETUS and then transplanted into the malfunctioning organ (pancreas) of an individual with a disorder of that organ (in this case, diabetes). The cells from the fetus are intended to take over the function of the host’s diseased or damaged cells. Fetal brain cells have also been transplanted into brains of people suffering from PARKINSONISM. These treatments are at an experimental stage.... fetal transplant
A popular term applied to any new formation in any part of the body. (See CANCER; CYSTS; GANGLION; TUMOUR.) For growth of children, see WEIGHT AND HEIGHT.... growth
(American) A classy lady Chartrah... chartra
(French) One who plans Chartrys... chartres
A disorder of newborn infants that is caused by the toxic effects on the growing FETUS of excessive amounts of alcohol taken by the mother. Low birth-weight and retarded growth are the main consequences, but affected babies may have hand and facial deformities and are sometimes mentally retarded.... fetal alcohol syndrome
The Ottawa Charter for Health Promotion of 1986 identifies three basic strategies for health promotion. These are advocacy for health to create essential conditions for health; enabling all people to achieve their full health potential; and mediating between the different interests in society in the pursuit of health. These strategies are supported by five priority action areas: build health public policy; create supportive environments for health; strengthen community action for health; develop personal skills; and reorient health services.... ottawa charter for health promotion
a group of *growth factors that promote new bone formation. Bone morphogenic protein (BMP), a naturally occurring substance that induces *osteoblast formation, has been genetically synthesized to form bone morphogenetic protein, which stimulates new bone formation and assists with fracture healing. Other bone growth factors include a type of transforming growth factor (TGF?) and insulin-like growth factor II (IGF-II), which encourage collagen formation.... bone growth factors
n. continuous hyperfractionated accelerated radiotherapy: a radiotherapy technique aimed at the rapid destruction of tumour cells when they are actively proliferating – and therefore most sensitive to radiation – by treating them several times a day over a greatly shortened total treatment time. The technique has been shown to be of benefit in the treatment of lung cancer.... chart
The increase in height and weight as a child develops. The period of most rapid growth occurs before birth. After birth, although growth is still rapid in the first few years of life, especially in the first year, the rate of
growth steadily decreases. Puberty marks another major period of growth, which continues until adult height and weight are reached, usually at about age 16–17 in girls and 19–21 in boys.
Body shape changes during childhood because different areas grow at different rates. For example, at birth, the head is already about three quarters of its adult size; it grows to almost full size during the first year. Thereafter, it becomes proportionately smaller because the body grows at a much faster rate.
Growth can be influenced by heredity and by environmental factors such as nutrition and general health. Hormones also play an important role, particularly growth hormone, thyroid hormones, and, at puberty, the sex hormones.
A chronic illness, such as cystic fibrosis, may retard growth. Even a minor illness can slow growth briefly, although the growth rate usually catches up when the child recovers. In some cases, slow growth may be the only sign that a child is ill or malnourished, in which case it is known as failure to thrive. However, short stature does not necessarily indicate poor health. Abnormally rapid growth is rare. Usually, it is a familial trait, but it may occasionally indicate an underlying disorder, such as a pituitary gland tumour causing gigantism. (See also age; child development.)... growth, childhood
a graph with lines showing average measurements of height, weight, and head circumference compared with age and sex, against which the physical development of a child or fetus can be assessed. The lines of growth on the graph are called centiles, and the number of a centile predicts the percentage of individuals who are below that measurement for a given age; for example, the 10th centile means that 10% of the age- and sex-matched population will be smaller and 90% will be bigger. A child or fetus will normally follow a particular centile, but if growth crosses centiles or lies outside the 97th or 3rd centiles, further investigation may be warranted.... centile chart
(EGFR) a protein on the surface of cells (see receptor) that binds with epidermal *growth factor and is therefore involved in cell division. EGFR is expressed at increased levels in numerous tumours, particularly of the head and neck, and in colorectal cancer, in which it can be a target for antibody therapy with *cetuximab. *Tyrosine kinase inhibitors acting specifically on the EGFR include gefitinib and erlotinib in lung and pancreatic cancer.... epidermal growth factor receptor
(FASD, fetal alcohol syndrome, FAS) a condition of newborn babies that results from the toxic effects on the fetus of maternal alcohol abuse. Babies have a low birth weight and growth is retarded. They have a small head (*microcephaly), low-set ears, eye, nose, lip, and nail abnormalities, and disturbances of behaviour and intellect. The greater the alcohol abuse, the more severe the fetal manifestations.... fetal alcohol spectrum disorder
see intrauterine growth restriction.... fetal growth restriction
(fetal graft) the introduction of an ovum, fertilized in vitro and developed to the *blastocyst stage, into the uterus of a postmenopausal woman in order that she may become pregnant. Before this procedure, the woman’s uterus must be prepared, by hormone therapy, to receive and nurture the blastocyst. Hormone treatment is continued throughout the pregnancy.... fetal implant
an electrical wire set into a sharp spiral metal tip and encased in a plastic sheath. It is attached to the fetal scalp for direct measurement of fetal heart rate by electrical activity.... fetal scalp electrode
see physis.... growth plate
death of a fetus in the uterus after 24 weeks of gestation. See stillbirth.... intrauterine fetal death
(IUGR, fetal growth restriction) failure of a fetus to achieve its growth potential, resulting in the birth of a baby whose birth weight is abnormally low in relation to its gestational age (see small for gestational age). Causes include *uteroplacental insufficiency, maternal disease (e.g. infection, malnutrition, high blood pressure, smoking, and alcoholism), poor socioeconomic conditions, multiple pregnancy (e.g. twins), and fetal disease or chromosomal abnormalities. It may be associated with *preterm birth.... intrauterine growth restriction
a chart for testing *visual acuity in which the rows of letters (optotypes) vary in size in a logarithmic progression. The space between the letters in a row and the space between each row is identical to the size of the letters in that row. This neutralizes the effect of crowding on vision. There are five letters in each row and each letter has a score of 0.02 log unit (the name derives from logarithm of the minimum angle of resolution). This makes it more accurate than a *Snellen chart and it is becoming increasingly used in testing vision. Most tests are done at a distance of 4 metres, allowing it to be used in smaller rooms. The acuity is scored as a number, with 1 being the same as 6/60 on the Snellen chart and 0 being equivalent to 6/6 (normal visual acuity). Vision better than 6/6 is scored as a negative, e.g. –0.18.... logmar chart
(NGF) a protein (see growth factor), consisting of two polypeptide chains, that is required for the development and longevity of some neurons, including those in the sympathetic nervous system and some central nervous system and sensory neurons. Nerve growth factor is necessary for axon growth and also for initiating new neuronal connections with other cells. The role of NGFs in preventing the degeneration of brain cells is being explored in research into Alzheimer’s disease.... nerve growth factor
(PDGF) see growth factor.... platelet-derived growth factor
(TGF) a protein – a *cytokine – that controls growth, proliferation, and other functions in most cells. It plays a role in asthma and other respiratory diseases and is also involved in diseases elsewhere in the body. There are two classes: TGF-? and TGF-?.... transforming growth factor
(VEGF) a *growth factor made by both normal cells and their abnormal or malignant counterparts to stimulate new blood vessel formation (see angiogenesis). It can be targeted by a family of drugs known as *angiogenesis inhibitors, which include *bevacizumab.... vascular endothelial growth factor
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