Action: Plant—emmenagogue, abortifacient. Seeds—narcotic, hypnotic, antispasmodic, anodyne and emetic; used in asthma, hiccough, colic, neuralgia, hysteria, dysmenorrhoea; used as abortifa- cient (properties similar to ergot, savine and rue). (Dried seeds constitute the drug Harmal of Indian medicine.)
The plant gave flavonoids—kaem- pferol, quercetin and acacetin. Aerial parts and seeds contain alkaloids— harmine, harmaline and harmalol (called harman alkaloids). Harman alkaloids from the seeds have been suggested for use in nervous diseases, and as coronary dilators and embolic. Harmol exhibits hypertensive activity. Harmine, vasicinone, deoxyvasici- none and 8-hydroxy glucosylharmine exhibit antitumour activity.The alkaloids, harmine, harmaline and harmol exhibit antibacterial and antifungal activity.The aqueous extract of seeds exhibited significant antiviral activity in vitro against herpes virus hominis type 1, slight activity was also observed against influenza viruses A and B. The plant extract exhibits significant analgesic activity.... peganum harmala
any attempt at self-injury or self-poisoning, as often occurs in the context of acute stress, personality disorder, depression, and alcoholism. It may or may not involve suicidal intent. Treatment begins with a psychosocial assessment, on the basis of which the patient may be offered various forms of *psychotherapy and occasionally *antipsychotic medication, *lithium, or *SSRIs. If the attempt is serious, immediate treatment may be necessary in a medical ward or (more rarely), if suicidal intent persists, in a psychiatric ward. Patients who do not have a mental disorder should be assessed using the criteria set out in the Mental Capacity Act 2005 and, if found to have *capacity, are entitled to consent to or refuse treatment like any other capacitous adult. See also suicide.... deliberate self-harm
n. physical, mental, or moral damage or the threat of this. Avoiding it is one of the ethical *four principles known as *nonmaleficence. Although health service staff have a clear duty to benefit patients and avoid harming them, in practice almost all medical actions run the risk of harming the patient and in some no good effect can be achieved without a clearly harmful process (such as mastectomy or chemotherapy for breast cancer). Therefore all medical professionals should learn how to make a *risk–benefit analysis at each point of care. The risk of harm should be explained to patients and their agreement obtained at each appropriate point. Professional blame or litigation may result if this is not done and harm results. See also primum non nocere; professionalism.... harm
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