Fluphenazine Health Dictionary

A group of major antipsychotic drugs, colloquially called ‘TRANQUILLISERS’, widely used to treat psychoses (see PSYCHOSIS). They can be divided into three main groups. Chlorpromazine, methotrimeprazine and promazine are examples of group 1, usually characterised by their sedative effects and moderate antimuscarinic and extrapyramidal side-effects. Group 2 includes pericyazine, pipothiazine and thioridazine, which have moderate sedative effects but signi?cant antimuscarinic action and modest extrapyramidal side-effects. Fluphenazine, perphenazine, prochlorperazine and tri?uoperazine comprise group 3. Their sedative effects are less than for the other groups and they have little antimuscarinic action; they have marked extrapyramidal side-effects.

Uses Phenothiazines should be prescribed and used with care. The drugs di?er in predominant actions and side-effects; selection depends on the extent of sedation required and the susceptibility of the patient to extrapyramidal side-effects. The di?erences between the drugs, however, are less important than the variabilities in patients’ responses. Patients should not be prescribed more than one antipsychotic drug at a time. In the short term these therapeutically powerful drugs can be used to calm disturbed patients, whatever the underlying condition (which might have a physical or psychiatric basis). They also alleviate acute anxiety and some have antidepressant properties, while others worsen DEPRESSION (see also MENTAL ILLNESS).... phenothiazines

A group of drugs used to treat psychotic illnesses (see antipsychotic drugs) and to relieve severe nausea and vomiting (see antiemetic drugs).

The group includes chlorpromazine, fluphenazine, and perphenazine.... phenothiazine drugs

n. see fluphenazine.... modecate

n. a phenothiazine *antipsychotic drug used to treat schizophrenia, mania, anxiety, and severe agitation and to prevent and treat severe nausea and vomiting. Side-effects are similar to those of *fluphenazine.... perphenazine